Compounds > rhinacanthone
Page last updated: 2024-09-05

rhinacanthone and itraconazole

rhinacanthone has been researched along with itraconazole in 1 studies

*Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis. [MeSH]

*Itraconazole: A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis. [MeSH]

Compound Research Comparison

Studies
(rhinacanthone)		Trials
(rhinacanthone)		Recent Studies (post-2010)
(rhinacanthone)		Studies
(itraconazole)		Trials
(itraconazole)		Recent Studies (post-2010) (itraconazole)
5022494108

Protein Interaction Comparison

ProteinTaxonomyrhinacanthone (IC50)itraconazole (IC50)
Tyrosine-protein kinase FynHomo sapiens (human)3.89
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.666
Cytochrome P450 3A4Homo sapiens (human)0.4256
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.2
C-X-C chemokine receptor type 1Homo sapiens (human)2.5676
CruzipainTrypanosoma cruzi3
Vasopressin V2 receptorHomo sapiens (human)3.476
C-C chemokine receptor type 4Homo sapiens (human)3.2689
Lanosterol 14-alpha demethylaseHomo sapiens (human)3.6
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Gong, Q; Hu, J; Li, X; Wang, P; Zhang, X1

Reviews

1 review(s) available for rhinacanthone and itraconazole

ArticleYear
A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; Drug Discovery; Humans; Naphthoquinones; Neoplasms; Tabebuia

2021