Page last updated: 2024-09-03

rhenium-186 hedp and docetaxel anhydrous

rhenium-186 hedp has been researched along with docetaxel anhydrous in 4 studies

Compound Research Comparison

Studies
(rhenium-186 hedp)
Trials
(rhenium-186 hedp)
Recent Studies (post-2010)
(rhenium-186 hedp)
Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010) (docetaxel anhydrous)
75321912,1103,2166,920

Protein Interaction Comparison

ProteinTaxonomyrhenium-186 hedp (IC50)docetaxel anhydrous (IC50)
Kinesin-like protein KIF11Homo sapiens (human)0.0014
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)5.0119

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bloemendal, HJ; de Haas, MJ; de Klerk, JM; O'Sullivan, JM; van Bezooijen, BP; van Dodewaard-de Jong, JM; Wilson, RH1
Bloemendal, HJ; de Klerk, JM; Geldof, AA; Hendrikse, NH; Lange, R; Paap, M; ter Heine, R; Tromp, AM; van Wieringen, WN1
Bloemendal, HJ; Bouman-Wammes, EW; de Klerk, JMH; van den Eertwegh, AJM; van Dodewaard-de Jong, JM; Verheul, HMW1
Beeker, A; Bloemendal, HJ; de Klerk, JMH; Hoekstra, OS; Jonker, MA; Los, M; O'Sullivan, JM; Oprea-Lager, DE; van den Berg, HP; van den Eertwegh, AJM; van Dodewaard-de Jong, JM; Verheul, HMW1

Trials

3 trial(s) available for rhenium-186 hedp and docetaxel anhydrous

ArticleYear
A phase I study of combined docetaxel and repeated high activity 186Re-HEDP in castration-resistant prostate cancer (CRPC) metastatic to bone (the TAXIUM trial).
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:11

    Topics: Aged; Bone Neoplasms; Chemoradiotherapy; Docetaxel; Etidronic Acid; Humans; Male; Middle Aged; Orchiectomy; Organometallic Compounds; Prostatic Neoplasms; Radiotherapy Dosage; Taxoids; Treatment Outcome

2011
A Phase 1 Trial of Cabazitaxel Combined With 188Re-Hydroxyethylidene Diphosphonate in Patients With Metastatic Castration-Resistant Prostate Cancer Who Progressed on or After a Docetaxel-Containing Treatment: The ReCab Trial.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Etidronic Acid; Humans; Male; Middle Aged; Neoplasm Metastasis; Organometallic Compounds; Prostatic Neoplasms, Castration-Resistant; Taxoids; Treatment Outcome

2017
A randomised, phase II study of repeated rhenium-188-HEDP combined with docetaxel and prednisone versus docetaxel and prednisone alone in castration-resistant prostate cancer (CRPC) metastatic to bone; the Taxium II trial.
    European journal of nuclear medicine and molecular imaging, 2017, Volume: 44, Issue:8

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Disease-Free Survival; Docetaxel; Etidronic Acid; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Organometallic Compounds; Prednisone; Prostatic Neoplasms, Castration-Resistant; Taxoids

2017

Other Studies

1 other study(ies) available for rhenium-186 hedp and docetaxel anhydrous

ArticleYear
Cytotoxic Effects of the Therapeutic Radionuclide Rhenium-188 Combined with Taxanes in Human Prostate Carcinoma Cell Lines.
    Cancer biotherapy & radiopharmaceuticals, 2017, Volume: 32, Issue:1

    Topics: Antineoplastic Agents; Bone Neoplasms; Cell Line, Tumor; Chemoradiotherapy; Chemotherapy, Adjuvant; DNA Repair; Docetaxel; Dose-Response Relationship, Drug; Etidronic Acid; Humans; Male; Organometallic Compounds; Prostatic Neoplasms; Radiation-Sensitizing Agents; Radiopharmaceuticals; Taxoids

2017