rhein has been researched along with sennoside a&b in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (27.27) | 18.7374 |
| 1990's | 7 (31.82) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| de Witte, P; Geboes, K; Lemli, J; Nijs, G | 1 |
| Autore, G; Caliendo, G; Capasso, F; Pepe, A | 1 |
| Leng-Peschlow, E | 3 |
| Kuwano, S; Miyawaki, Y; Nishikawa, T; Yagi, T; Yamauchi, K | 1 |
| Lemli, J | 1 |
| Cameron, BD; Fenerty, CA; Phillips, MW | 1 |
| Odenthal, KP; Ziegler, D | 1 |
| Krumbiegel, G; Schulz, HU | 1 |
| de Witte, P | 1 |
| Grimminger, W; Witthohn, K | 1 |
| De, B; Dutta, A; Mukherjee, A; Mukhopadhyay, MJ; Saha, A | 1 |
| Choi, SB; Jang, JS; Ko, BS; Park, S; Park, SK | 1 |
| Amen, RJ; Greenway, FL; Kai-yuan, W; Liu, Z; Martin, CK; Nofziger, J; Rood, JC; Yu, Y | 1 |
| Kaukonen, AM; Laitinen, L; Marvola, M; Takala, E; Vuorela, H; Vuorela, P | 1 |
| Kobayashi, N; Koyama, J; Morita, I | 1 |
| Li, A; Wang, H; Wang, JK; Xu, XY | 1 |
| Ishizu, T; Okamura, N; Takayama, K; Tsutsumi, H | 1 |
| Arnatt, CK; Guo, C; Li, X; Wang, XY; Yu, X; Yuan, Y; Zaidi, SA; Zhang, Y | 1 |
| Deng, C; Liu, JJ; Wang, HY; Wang, J; Yan, YG; Yin, LM | 1 |
| Cheng, Y; He, Y; Qiao, B; Qu, L; Routledge, MN; Yun Gong, Y; Zhang, H | 1 |
1 review(s) available for rhein and sennoside a&b
| Article | Year |
|---|---|
Metabolism and pharmacokinetics of anthranoids.
Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Digestive System; Humans; Intestinal Absorption; Senna Extract; Sennosides | 1993 |
1 trial(s) available for rhein and sennoside a&b
| Article | Year |
|---|---|
Safety and efficacy of NT, an herbal supplement, in treating human obesity.
Topics: Adolescent; Adult; Anthraquinones; Appetite Depressants; Body Mass Index; Dietary Supplements; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Eating; Female; Freeze Drying; Gallic Acid; Humans; Middle Aged; Obesity; Phytotherapy; Pilot Projects; Senna Extract; Sennosides; Treatment Outcome; Weight Loss | 2006 |
20 other study(ies) available for rhein and sennoside a&b
| Article | Year |
|---|---|
Influence of rhein anthrone and rhein on small intestine transit rate in rats: evidence of prostaglandin mediation.
Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Transit; Intestine, Small; Male; Rats; Rats, Inbred Strains; Senna Extract; Sennosides; Time Factors | 1992 |
Perfusion of rat colon with sennosides, rhein and rheinanthrone. Concentration-related histamine release.
Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Colon; Dose-Response Relationship, Drug; Histamine Release; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains; Senna Extract; Sennosides | 1990 |
Effects of sennosides A + B and bisacodyl on rat large intestine.
Topics: Administration, Oral; Animals; Anthraquinones; Bisacodyl; Body Water; Cathartics; Colon; Cresols; Electrolytes; Feces; Female; Gastrointestinal Transit; Intestinal Absorption; Intestine, Large; NADH, NADPH Oxidoreductases; Rats; Rats, Inbred Strains; Senna Extract; Sennosides | 1989 |
Involvement of prostaglandin E-like material in the purgative action of rhein anthrone, the intraluminal active metabolite of sennosides A and B in mice.
Topics: Animals; Anthraquinones; Barium Sulfate; Cathartics; Diarrhea; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Female; Gastrointestinal Transit; Indomethacin; Mice; Mice, Inbred ICR; Polyphloretin Phosphate; Prostaglandins E; Senna Extract; Sennosides | 1988 |
Metabolism of sennosides--an overview.
Topics: Animals; Anthraquinones; Humans; Intestinal Absorption; Intestinal Mucosa; Senna Extract; Sennosides | 1988 |
Milk transfer of rhein in the rhesus monkey.
Topics: Animals; Anthraquinones; Cathartics; Female; Lactation; Macaca mulatta; Milk; Pregnancy; Senna Extract; Sennosides | 1988 |
In vitro effects of anthraquinones on rat intestine and uterus.
Topics: Acetylcholine; Animals; Anthraquinones; Colon; Female; Gastrointestinal Motility; Ileum; In Vitro Techniques; Rats; Rats, Inbred Strains; Senna Extract; Sennosides; Uterine Contraction | 1988 |
[Mode of action of anthraquinone laxatives on the rat].
Topics: Animals; Anthraquinones; Cathartics; Colon; Female; Rats; Rats, Inbred Strains; Senna Extract; Sennosides | 1987 |
Sennoside-induced secretion is not caused by changes in mucosal permeability or Na+,K(+)-ATPase activity.
Topics: Animals; Anthraquinones; Ca(2+) Mg(2+)-ATPase; Cathartics; Cell Membrane Permeability; Erythritol; Female; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; NADH, NADPH Oxidoreductases; Rats; Rats, Wistar; Senna Extract; Sennosides; Sodium; Sodium-Potassium-Exchanging ATPase | 1993 |
Rhein and aloe-emodin kinetics from senna laxatives in man.
Topics: Adolescent; Adult; Anthraquinones; Cassia; Cathartics; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Intestinal Absorption; Male; Plant Extracts; Plantago; Plants, Medicinal; Senna Extract; Sennosides | 1993 |
Analytics of senna drugs with regard to the toxicological discussion of anthranoids.
Topics: Anthraquinones; Cathartics; Chromatography, High Pressure Liquid; Emodin; Prodrugs; Risk Factors; Senna Extract; Sennosides | 1993 |
Genotoxicity of sennosides on the bone marrow cells of mice.
Topics: Administration, Oral; Animals; Anthraquinones; Bone Marrow Cells; Cassia; Cathartics; Chromosome Aberrations; Male; Mice; Mutagens; Plant Extracts; Plants, Medicinal; Senna Extract; Sennosides | 1998 |
Insulin sensitizing and alpha-glucoamylase inhibitory action of sennosides, rheins and rhaponticin in Rhei Rhizoma.
Topics: Adipocytes; Animals; Anthraquinones; Blood Pressure; Body Weight; Cell Differentiation; Cell Line; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Ethanol; Fibroblasts; Glucan 1,4-alpha-Glucosidase; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Senna Extract; Sennosides; Solvents; Stilbenes; Triglycerides | 2006 |
Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2).
Topics: Absorption; Acetaminophen; Anthraquinones; Beverages; Caco-2 Cells; Carbon Radioisotopes; Cathartics; Cell Membrane Permeability; Digoxin; Furosemide; Humans; Ketoprofen; Mannitol; Plant Leaves; Propranolol; Senna Extract; Sennosides; Verapamil | 2007 |
Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis.
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Emodin; Glucosides; Molecular Structure; Reproducibility of Results; Rheum; Senna Extract; Sennosides | 2007 |
[Comparative studies on purgative potency among three spieces of certified rhubarb].
Topics: Animals; Anthraquinones; Cathartics; Cell Membrane; China; Chromatography, High Pressure Liquid; Colon; Drugs, Chinese Herbal; Epithelial Cells; Female; Male; Mice; Mice, Inbred ICR; Rheum; Senna Extract; Sennosides; Sodium-Potassium-Exchanging ATPase; Species Specificity | 2006 |
The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice.
Topics: Animals; Anthracenes; Anthraquinones; Bacteria; Cathartics; Constipation; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Emodin; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred Strains; Monosaccharides; Phytotherapy; Rheum; Senna Extract; Sennosides | 2012 |
Small molecule inhibits activity of scavenger receptor A: Lead identification and preliminary studies.
Topics: Animals; Anthraquinones; Antineoplastic Agents; beta-Galactosidase; Dendritic Cells; Drug Design; Humans; Interferon Regulatory Factor-3; Lymphocyte Activation; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Poly I-C; Scavenger Receptors, Class A; Senna Extract; Sennosides; Small Molecule Libraries; Structure-Activity Relationship; T-Lymphocytes; Toll-Like Receptors; Transcription Factors | 2015 |
[The Effect in Extraction of Different Ratio of Dahuang-Taoren for Ten Kinds of Chemical Constituents from Rhizoma Rhei].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Rheum; Rhizome; Senna Extract; Sennosides | 2016 |
Identification of rhein as the metabolite responsible for toxicity of rhubarb anthraquinones.
Topics: Animals; Anthraquinones; Apoptosis; Autophagy; Biotransformation; Cathartics; Chromatography, High Pressure Liquid; Colon; Diarrhea; Feces; Gastrointestinal Microbiome; HT29 Cells; Humans; Laxatives; Male; Rats, Sprague-Dawley; Rheum; Sennosides | 2020 |