rhein and aloe emodin
rhein has been researched along with aloe emodin in 68 studies
Research
Studies (68)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (4.41) | 18.2507 |
| 2000's | 18 (26.47) | 29.6817 |
| 2010's | 35 (51.47) | 24.3611 |
| 2020's | 12 (17.65) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Kam, CM; Powers, JC; Zalkow, LH; Zembower, DE | 1 |
| Matsuda, H; Morikawa, T; Shimoda, H; Yoshikawa, M | 1 |
| Shang, X; Yuan, Z | 1 |
| Diao, C; Hu, D; Jin, L; Song, B; Xu, G; Yang, S; Zhou, X; Zou, Z | 1 |
| Coenye, T; Honraet, K; Nadal Jimenez, P; Nelis, HJ; Rigole, P | 1 |
| Cui, XR; Gao, L; Komada, F; Koyanagi, J; Saito, S; Shimamura, T; Suzuki, N; Tsukada, M | 1 |
| Bergonzi, MC; Bilia, AR; Bindoli, A; Chioccioli, M; Gabbiani, C; Gratteri, P; Karioti, A; Messori, L; Rigobello, MP; Scutari, G; Sorrentino, F | 1 |
| Fischer, TC; Gosch, C; Gselmann, M; Mirbeth, B; Stich, K; Thallmair, V | 1 |
| Huang, W; Li, C; Shi, DH; Wang, LT; Wang, SF | 1 |
| Cheng, YX; Luo, J; Wang, PC; Wei, W; Yan, YM; Yang, Y; Yang, YX; Zhang, LS; Zhou, XJ | 1 |
| Huang, W; Li, C; Liu, YW; Shi, DH; Wang, SF | 1 |
| Adepally, U; Banothu, V; Chakrabarti, S; Kumar, K; Luthra, T; M, S; Maddi, SR; Sen, S | 1 |
| Inui, K; Kanamitsu, K; Katayama, W; Kitakami, R; Mizuguchi, M; Nakagawa, S; Nakagawa, Y; Okada, T; Sawai, Y; Toyooka, N; Yokoyama, T | 1 |
| Grimminger, W; Witthohn, K | 1 |
| Kuwano, S; Yagi, T; Yamauchi, K | 1 |
| He, J; Jiang, C | 1 |
| Correia, H; Fonseca, G; Fraile, G; Marcano, E; Marín, M; Sánchez, Y; Vargas, F; Velásquez, M | 1 |
| Shang, XY; Yuan, ZB | 1 |
| Chen, XG; Jia, W; Zheng, WJ | 1 |
| Bi, S; Kan, Y; Song, D; Tian, Y; Xu, D; Zhang, H; Zhou, X | 1 |
| Kobayashi, N; Koyama, J; Morita, I | 1 |
| Chou, GX; Lu, YH; Wei, DZ; Zhang, YZ; Zhu, EY | 1 |
| Chen, L; Duan, D; Luo, H; Xu, X; Zhuang, Y | 1 |
| Dong, H; Liu, Y; Song, R; Tian, Y; Xu, F; Zhang, Z | 1 |
| Deng, KW; He, FY; Liu, PA; Liu, WL; Zhou, HH | 1 |
| Bae, JJ; Bak, JP; Choung, ES; Kang, SC; Kwak, JH; Lee, CM; Yoo, HS; Zee, OP | 1 |
| Bian, BL; Fan, MX; Li, PY; Li, XM; Wang, HJ | 1 |
| Chen, S; Dong, J; Hashi, Y; Wan, L; Wang, H | 1 |
| Chen, YY; Chiang, SY; Chung, JG; Lai, TY; Liao, CL; Lin, JG; Ma, YS; Tang, NY; Yang, JS | 1 |
| Dong, H; Liu, Y; Song, R; Xu, F; Zhang, Z | 1 |
| Li, YX; Liu, Y; Suo, XB; Wu, YH | 1 |
| Fang, F; Jin, C; Kong, WJ; Wang, HJ; Wang, JB; Xiao, XH; Zhao, HP; Zhao, YL | 2 |
| Cheng, KM; Deng, X; Li, W; Liang, J; Xia, X; Yang, GL; Zhao, LC | 1 |
| Liang, YF; Zhang, ZX | 1 |
| Deng, JG; He, Y; Hu, XY; Yuan, YF | 1 |
| Chen, GY; Gong, HL; Huang, X; Tang, WF; Wang, J | 1 |
| Chen, GY; Chen, WW; Tang, WF; Wan, MH; Xiang, J; Yu, Q; Zhao, XL | 1 |
| Feng, SX; Li, JS; Qu, LB; Shi, YM; Zhao, D | 1 |
| Ishizu, T; Okamura, N; Takayama, K; Tsutsumi, H | 1 |
| Cai, B; Cai, H; Chen, J; Guo, H; Li, H; Liu, X; Wu, L; Zhang, K; Zhang, Y | 1 |
| Badria, FA; Ibrahim, AS | 1 |
| Cai, BC; Chen, LH; Li, JS; Liu, X; Peng, WW; Yang, GM; Zhang, YX | 1 |
| Asres, K; Bisrat, D; Terefe, G; Tewabe, Y | 1 |
| Hu, CJ; Jia, TZ; Xiao, HB; Zhang, XZ; Zhao, N | 1 |
| Chao, PD; Chen, MY; Hou, YC; Lin, SP; Peng, YH; Tsai, SY; Yu, CP | 1 |
| Li, HL; Shi, YB; Wang, H; Wang, HQ; Yang, YB; Zhang, CA; Zhang, XY; Zhang, ZY; Zhu, ZJ | 1 |
| Sun, YS; Wang, JH; Yang, SF | 1 |
| Gong, XH; Li, Y; Li, YX; Peng, C; Yuan, A; Zeng, DW; Zhang, RQ; Zhao, MJ | 1 |
| Dong, LC; Dong, X; Fan, YX; Li, HJ; Li, P; Ma, J; Yu, Q | 1 |
| Hou, YC; Hsieh, YW; Lin, HJ; Lin, SP; Shia, CS; Yu, CP | 1 |
| Chao, PL; Hou, YC; Huang, CY; Lin, SP; Yang, MS; Yu, CP | 1 |
| Li, J; Li, JY; Ren, HY; Su, H; Tang, WF; Wu, FS; Zhang, YM; Zhao, XL | 1 |
| Cai, Y; Fu, YJ; Jiang, SS; Jiang, XY; Peng, M; Peng, XQ; Shi, MQ; Wu, Y; Xu, Y; Yang, SY | 1 |
| Liu, QH; Sun, YW; Tong, XL; Wang, F; Wen, J; Zhang, X | 1 |
| Deng, C; Liu, JJ; Wang, HY; Wang, J; Yan, YG; Yin, LM | 1 |
| Baek, J; Brailsford, AD; Buddeberg, BS; Cho, BK; Cho, MJ; Choi, DH; Choi, K; Choi, YH; Cowan, DA; Gordon, IL; Hamblin, MR; Jang, JH; Kaelin Agten, A; Khalil, A; Kim, HJ; Kim, JH; Kim, KH; Kim, SI; Kim, SK; Kim, SW; Ko, JS; Koga, S; Lavery, LA; Lee, JH; Lee, JY; Li, H; Li, K; Liu, C; Liu, Q; Luo, X; Ma, MH; Majidin, WNM; Nong, F; O'Driscoll, JM; Osawa, M; Park, GE; Park, J; Park, SH; Pei, M; Phi, JH; Sakaue, H; Sengoku, Y; Sharma, R; Son, Y; Takagi, H; Thein, MS; Thilaganathan, B; Wakabayashi, H; Walker, C; Washington, K; Wason, J; Wen, B; Wojek, N; Yang, H; Zhao, Z; Zhou, L | 1 |
| Chewchinda, S; Sithisarn, P | 1 |
| Chen, J; Li, D; Lv, B; Qin, S; Wang, D; Xu, D; Xu, F; Zhang, W; Zhang, Y; Zhang, Z | 1 |
| Liu, Y; Mapa, MST; Sprando, RL | 1 |
| Alalaiwe, A; Chuang, SY; Fang, JY; Huang, TH; Lin, CF; Nguyen, TMH; Wang, PW | 1 |
| Fang, B; Huo, X; Ma, X; Sun, C; Tian, X; Wang, Y; Wu, F; Zhang, B; Zhang, Y; Zhao, T | 1 |
| Chen, XJ; Duan, J; Feng, Y; Guo, Y; Li, B; Li, H; Li, M; Li, S; Liu, H; Liu, K; Liu, M; Shi, R; Wang, D; Wang, X; Zhao, L | 1 |
| Chen, Q; Fang, B; Feng, L; Huo, X; Lv, X; Ma, X; Mei, Q; Sun, C; Tian, X; Wang, C; Wang, Y; Wu, F; Zhang, Y | 1 |
| Ahn, SH; Nguyen, LTH; Shin, HM; Yang, IJ | 1 |
| Wang, L; Yang, Y; Zhao, S; Zhou, G | 1 |
| Chen, W; Li, S; Ma, Y; Wu, X; Zhang, H | 1 |
| Chen, W; Li, S; Ma, Y | 1 |
Other Studies
68 other study(ies) available for rhein and aloe emodin
| Article | Year |
|---|---|
Novel anthraquinone inhibitors of human leukocyte elastase and cathepsin G.
Topics: Anthraquinones; Cathepsin G; Cathepsins; Humans; Leukocyte Elastase; Pancreatic Elastase; Serine Endopeptidases; Structure-Activity Relationship | 1992 |
Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity.
Topics: Anthraquinones; Cell Division; Cells, Cultured; Emodin; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Genistein; Humans; Isoflavones; Phytoestrogens; Plant Preparations; Polygonaceae; Protein Binding; Receptors, Estrogen; Structure-Activity Relationship | 2001 |
Determination of active components in rhubarb and study of their hydrophobicity by micellar electrokinetic chromatography.
Topics: Anthraquinones; Calibration; Chromatography, Micellar Electrokinetic Capillary; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Plant Extracts; Rheum; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Styrenes; Thermodynamics | 2003 |
Isolation and inhibitory activity against ERK phosphorylation of hydroxyanthraquinones from rhubarb.
Topics: Animals; Anthraquinones; Antifungal Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, Gel; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Mice; Microwaves; NIH 3T3 Cells; Phosphorylation; Plant Extracts; Rheum; Spectrum Analysis | 2006 |
In vitro inhibition of Streptococcus mutans biofilm formation on hydroxyapatite by subinhibitory concentrations of anthraquinones.
Topics: Anthraquinones; Anti-Bacterial Agents; Biofilms; Durapatite; Microbial Sensitivity Tests; Streptococcus mutans | 2007 |
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones.
Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Boraginaceae; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lithospermum; Magnetic Resonance Spectroscopy; Naphthoquinones; Rheum; Spectrometry, Mass, Electrospray Ionization | 2008 |
Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones.
Topics: Amino Acid Sequence; Anthracenes; Inhibitory Concentration 50; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Perylene; Sequence Homology, Amino Acid; Thioredoxin-Disulfide Reductase | 2011 |
Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora.
Topics: Agrochemicals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Drug Stability; Erwinia amylovora; Flowers; Germination; Hydrogen-Ion Concentration; Malus; Microbial Sensitivity Tests; Naphthoquinones; Plant Diseases; Quinones; Toxicity Tests | 2012 |
Synthesis, biological evaluation and molecular modeling of aloe-emodin derivatives as new acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Anthraquinones; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Kinetics; Molecular Docking Simulation; Protein Binding; Structure-Activity Relationship; Tacrine | 2013 |
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.
Topics: Anthraquinones; Aspergillus fumigatus; Cell Survival; Diabetic Nephropathies; Dose-Response Relationship, Drug; Extracellular Matrix; Glycosides; Humans; Interleukin-6; Mesangial Cells; Molecular Structure; Naphthalenes; Renal Insufficiency, Chronic; Rumex; Structure-Activity Relationship | 2013 |
Design, synthesis and molecular modeling of aloe-emodin derivatives as potent xanthine oxidase inhibitors.
Topics: Aloe; Animals; Anthraquinones; Catalytic Domain; Cattle; Drug Design; Enzyme Inhibitors; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship; Xanthine Oxidase | 2014 |
Discovery of novel pyrido-pyrrolidine hybrid compounds as alpha-glucosidase inhibitors and alternative agent for control of type 1 diabetes.
Topics: alpha-Glucosidases; Animals; Binding Sites; Blood Proteins; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Drug Discovery; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Male; Mice; Molecular Docking Simulation; Molecular Structure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Solubility; Streptozocin; Structure-Activity Relationship; Thermodynamics | 2020 |
Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.
Topics: Amyloid Neuropathies, Familial; Anthraquinones; Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Xanthones | 2021 |
Analytics of senna drugs with regard to the toxicological discussion of anthranoids.
Topics: Anthraquinones; Cathartics; Chromatography, High Pressure Liquid; Emodin; Prodrugs; Risk Factors; Senna Extract; Sennosides | 1993 |
The synergistic purgative action of aloe-emodin anthrone and rhein anthrone in mice: synergism in large intestinal propulsion and water secretion.
Topics: Animals; Anthraquinones; Body Water; Cathartics; Drug Synergism; Emodin; Female; Intestine, Large; Mice; Mice, Inbred ICR; Senna Extract | 1997 |
Simultaneous determination of Aloe-emodin and Rhein by synchronous fluorescence spectroscopy.
Topics: Anthraquinones; Drug Combinations; Emodin; Hydrogen-Ion Concentration; Indicators and Reagents; Spectrometry, Fluorescence | 2002 |
Studies on the photostability and phototoxicity of aloe-emodin, emodin and rhein.
Topics: Acetylcholinesterase; Aloe; Anthraquinones; Dermatitis, Phototoxic; Drug Stability; Emodin; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Linoleic Acid; Lipid Peroxidation; Photochemistry; Reactive Oxygen Species; Ultraviolet Rays | 2002 |
[Determination of six effective components in Rheum by cyclodextrin modified micellar electrokinetic chromatography].
Topics: Anthraquinones; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Emodin; Plants, Medicinal; Quality Control; Rheum; Stilbenes | 2002 |
[Determination of active anthraquinones in Rheum and its tea preparations by micellar electrokinetic capillary electrophoresis].
Topics: Anthraquinones; Chromatography, Micellar Electrokinetic Capillary; Emodin; Plant Preparations; Plants, Medicinal; Rheum | 2004 |
Spectroscopic characterization of effective components anthraquinones in Chinese medicinal herbs binding with serum albumins.
Topics: Anthraquinones; Binding Sites; Drugs, Chinese Herbal; Emodin; Humans; Models, Molecular; Molecular Structure; Serum Albumin; Serum Albumin, Bovine | 2005 |
Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis.
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Emodin; Glucosides; Molecular Structure; Reproducibility of Results; Rheum; Senna Extract; Sennosides | 2007 |
Preparative isolation and purification of hydroxyanthraquinones from Rheum tanguticum Maxim. on normal phase silica gel: using a Flash Master Personal system.
Topics: Anthraquinones; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Emodin; Glucosides; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Plants, Medicinal; Rheum; Silica Gel; Silicon Dioxide; Spectrophotometry, Ultraviolet | 2007 |
In situ synthesis of molecularly imprinted polymers on glass microspheres in a column.
Topics: Acrylamide; Anthraquinones; Chromatography, Liquid; Emodin; Glass; Methacrylates; Microscopy, Electron, Scanning; Microspheres; Molecular Imprinting; Molecular Structure; Nitriles; Polymers; Pressure; Rheology; Solid Phase Extraction | 2007 |
Rapid simultaneous quantification of five active constituents in rat plasma by high-performance liquid chromatography/tandem mass spectrometry after oral administration of Da-Cheng-Qi decoction.
Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2008 |
[A new qualitative and quantitative analytical method of chromatographic fingerprints: total quantum statistical moment].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Ecosystem; Emodin; Plant Roots; Plants, Medicinal; Quantum Theory; Rheum | 2008 |
Anti-proliferative effects of estrogen receptor-modulating compounds isolated from Rheum palmatum.
Topics: Anthraquinones; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Emodin; Estrogen Receptor Modulators; Humans; Inhibitory Concentration 50; Plant Roots; Receptors, Estrogen; Recombinant Proteins; Rheum | 2008 |
[Studies on chemical constituents and volatile oil of Xiaochengqi decoction].
Topics: Anthraquinones; Biphenyl Compounds; Cinnamates; Cyclohexenes; Cymenes; Drugs, Chinese Herbal; Emodin; Gallic Acid; Gas Chromatography-Mass Spectrometry; Lignans; Limonene; Monoterpenes; Oils, Volatile; Sitosterols; Terpenes | 2008 |
[Identification and determination of major constituents in Polygonum cuspidatum Sieb. et Zucc. by high performance liquid chromatography/electrospray ionization-ion trap-time-of-flight mass spectrometry].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2009 |
Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
Topics: 14-3-3 Proteins; Anthraquinones; Ataxia Telangiectasia Mutated Proteins; Biomarkers, Tumor; BRCA1 Protein; Cell Cycle Proteins; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; DNA-Activated Protein Kinase; DNA-Binding Proteins; Emodin; Enzyme Inhibitors; Exonucleases; Exoribonucleases; Gene Expression; Humans; Neoplasm Proteins; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Tongue Neoplasms; Tumor Suppressor Proteins | 2010 |
Pharmacokinetic comparison in rats of six bioactive compounds between Da-Cheng-Qi decoction and its parent herbal medicines.
Topics: Animals; Anthraquinones; Area Under Curve; Biphenyl Compounds; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Female; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2010 |
[Liposomal encapsulation of free anthraquinones in rhizoma et radix rhei and its quality control].
Topics: Anthraquinones; Calcium; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Drugs, Chinese Herbal; Emodin; Liposomes; Particle Size; Quality Control; Reproducibility of Results; Rheum; Rhizome | 2010 |
[Tissue distribution of free anthraquinones in SD rats after orally administered extracts from raw and prepared rhubarbs].
Topics: Administration, Oral; Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Female; Male; Plant Roots; Plants, Medicinal; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum; Tandem Mass Spectrometry; Tissue Distribution | 2011 |
The use of response surface methodology to optimize the ultrasound-assisted extraction of five anthraquinones from Rheum palmatum L.
Topics: Anthraquinones; Emodin; Rheum; Ultrasonics | 2011 |
A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract.
Topics: Administration, Oral; Animals; Anthraquinones; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Female; Kidney; Liver; Male; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rheum; Spleen; Tandem Mass Spectrometry; Tissue Distribution | 2011 |
[Study on chemical constituents from the root of Hemerocallis citrina].
Topics: Anthraquinones; Hemerocallis; Microwaves; Plant Roots; Plants, Edible; Plants, Medicinal; Powders; Spectrophotometry, Ultraviolet | 2011 |
Synthesis and anti-tumor activity evaluation of rhein-aloe emodin hybrid molecule.
Topics: Anthraquinones; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Molecular Structure | 2012 |
Effect of formula compatibility on the pharmacokinetics of components from Dachengqi Decoction [See Text] in rats.
Topics: Administration, Oral; Animals; Anthraquinones; Biphenyl Compounds; Drug Incompatibility; Emodin; Flavanones; Hesperidin; Lignans; Male; Plant Extracts; Rats; Rats, Sprague-Dawley | 2012 |
Effect of acute pancreatitis on the pharmacokinetics of Chinese herbal ointment Liu-He-Dan in anaesthetized rats.
Topics: Administration, Cutaneous; Amylases; Animals; Anthraquinones; Arginine; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Male; Ointments; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley | 2013 |
Comparative pharmacokinetics of five rhubarb anthraquinones in normal and thrombotic focal cerebral ischemia-induced rats.
Topics: Animals; Anthraquinones; Brain Ischemia; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum | 2013 |
The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice.
Topics: Animals; Anthracenes; Anthraquinones; Bacteria; Cathartics; Constipation; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Emodin; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred Strains; Monosaccharides; Phytotherapy; Rheum; Senna Extract; Sennosides | 2012 |
Comparative pharmacokinetics study of three anthraquinones in rat plasma after oral administration of Radix et Rhei Rhizoma extract and Dahuang Fuzi Tang by high performance liquid chromatography-mass spectrometry.
Topics: Aconitum; Administration, Oral; Animals; Anthraquinones; Asarum; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Male; Mass Spectrometry; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum; Sensitivity and Specificity; Time Factors | 2013 |
Evaluation of natural anthracene-derived compounds as antimitotic agents.
Topics: Anthracenes; Anthraquinones; Antimitotic Agents; Antineoplastic Agents; Dose-Response Relationship, Drug; Emodin; Mitosis; Onions; Plant Roots; Time Factors | 2013 |
Comparative pharmacokinetics of aloe-emodin, rhein and emodin determined by liquid chromatography-mass spectrometry after oral administration of a rhubarb peony decoction and rhubarb extract to rats.
Topics: Aloe; Animals; Anthraquinones; Area Under Curve; Calibration; Cathartics; Chromatography, High Pressure Liquid; Linear Models; Male; Mass Spectrometry; Organization and Administration; Paeonia; Plant Extracts; Quality Control; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Rheum | 2013 |
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
[Metabolomics analysis revealing multiple compounds changed in rhubarb after processing].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Food Handling; Food Preservation; Metabolomics; Multivariate Analysis; Principal Component Analysis; Rheum; Tandem Mass Spectrometry | 2014 |
Serum concentrations of anthraquinones after intake of Folium Sennae and potential modulation on P-glycoprotein.
Topics: Administration, Oral; Animals; Anthraquinones; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Glucuronides; Humans; Male; Plant Leaves; Plants, Medicinal; Rats, Sprague-Dawley; Senna Plant | 2014 |
Simultaneous determination of five anthraquinones in a Chinese traditional preparation by RP-HPLC using an improved extraction procedure.
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Emodin | 2014 |
[Optimization of ionic liquid based microwave assisted extraction of five anthraquinones from Polygonum cuspidatum by response surface method].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Ionic Liquids; Microwaves; Plant Roots; Rhizome; Technology, Pharmaceutical; Temperature | 2014 |
The Influence of Aconitum carmichaelii Debx. on the Pharmacokinetic Characteristics of Main Components in Rheum palmatum L.
Topics: Aconitum; Administration, Oral; Animals; Anthraquinones; Drug Interactions; Drugs, Chinese Herbal; Emodin; Male; Plant Extracts; Plant Roots; Rats, Sprague-Dawley; Rheum; Rhizome | 2015 |
Synergistic effects of rhubarb-gardenia herb pair in cholestatic rats at pharmacodynamic and pharmacokinetic levels.
Topics: 1-Naphthylisothiocyanate; Alanine Transaminase; Alkaline Phosphatase; Animals; Anthraquinones; Aspartate Aminotransferases; Bilirubin; Cholestasis; Drug Synergism; Emodin; Fruit; Gardenia; Iridoids; Liver; Male; Plant Extracts; Protective Agents; Rats, Sprague-Dawley; Rheum; Rhizome | 2015 |
Analysis of the pharmacokinetics and metabolism of aloe-emodin following intravenous and oral administrations in rats.
Topics: Administration, Oral; Animals; Anthraquinones; Chromatography, High Pressure Liquid; Infusions, Intravenous; Rats | 2016 |
Aloe activated P-glycoprotein and CYP 3A: a study on the serum kinetics of aloe and its interaction with cyclosporine in rats.
Topics: Aloe; Animals; Anthraquinones; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 CYP3A; Kinetics; Male; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley | 2017 |
Pharmacokinetics and pharmacodynamics of Da-Cheng-Qi decoction in the liver of rats with severe acute pancreatitis.
Topics: Acute Disease; Alanine Transaminase; Animals; Anthraquinones; Aspartate Aminotransferases; Biphenyl Compounds; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Flavanones; Hesperidin; Inflammation; Lignans; Liver; Male; Pancreatitis; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2017 |
[Effects of wine processed Rheum palmatum on tissue distribution of aloe-emodin, rhein and emodin in rats].
Topics: Animals; Anthraquinones; Emodin; Rats; Rats, Sprague-Dawley; Rheum; Tissue Distribution; Wine | 2017 |
[Comparative Study on Boiling Powder and Traditional Herbal Pieces of Rhubarb].
Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Powders; Rats; Rats, Sprague-Dawley; Rheum | 2016 |
[The Effect in Extraction of Different Ratio of Dahuang-Taoren for Ten Kinds of Chemical Constituents from Rhizoma Rhei].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Rheum; Rhizome; Senna Extract; Sennosides | 2016 |
Topics: Adult; Anabolic Agents; Androgens; Animals; Anthraquinones; Birth Weight; Body Mass Index; Carbon Isotopes; Cardiac Output; Case-Control Studies; Chromatography, High Pressure Liquid; Doping in Sports; Drugs, Chinese Herbal; Echocardiography; Emodin; Estranes; Exercise; Female; Gas Chromatography-Mass Spectrometry; Glucosides; Glycolysis; Hemodynamics; Hemoglobins; Herb-Drug Interactions; Humans; Hypothermia, Induced; Lactic Acid; Linear Models; Male; Monoterpenes; Muscle, Skeletal; Myoglobin; Nandrolone; Obesity; Oxygen Consumption; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Pregnant Women; Prospective Studies; Pulmonary Gas Exchange; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Steroids; Substance Abuse Detection; Sulfates; Tandem Mass Spectrometry; Testosterone | 2018 |
Simultaneous HPTLC Determination of Rhein and Aloe-emodin in Senna alata Leaves from Thailand and their Commercial Products.
Topics: Anthraquinones; Chromatography, Thin Layer; Plant Leaves; Reproducibility of Results; Senna Plant; Sensitivity and Specificity; Thailand | 2017 |
Network Pharmacology and Bioactive Equivalence Assessment Integrated Strategy Driven Q-markers Discovery for Da-Cheng-Qi Decoction to Attenuate Intestinal Obstruction.
Topics: Algorithms; Animals; Anthraquinones; Biomarkers, Pharmacological; Biphenyl Compounds; Data Mining; Drugs, Chinese Herbal; Flavanones; HT29 Cells; Humans; Intestinal Obstruction; Lignans; Male; Phosphatidylinositol 3-Kinases; Rats, Sprague-Dawley; Reproducibility of Results; Therapeutic Equivalency | 2020 |
Anthraquinones inhibit cytochromes P450 enzyme activity in silico and in vitro.
Topics: Animals; Anthraquinones; Computer Simulation; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Emodin; Humans; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Quantitative Structure-Activity Relationship; Recombinant Proteins | 2021 |
A systematic comparison of the effect of topically applied anthraquinone aglycones to relieve psoriasiform lesion: The evaluation of percutaneous absorption and anti-inflammatory potency.
Topics: Administration, Topical; Animals; Anthraquinones; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Emodin; HaCaT Cells; Humans; Imiquimod; Inflammation; Keratinocytes; Macrophages; Mice; Psoriasis; Rheum; Skin Absorption; Swine | 2022 |
Simultaneous Determination of Ten Active Components From Jinhongtang Granule in Rat Plasma by LC-MS/MS and its Application to a Comparative Pharmacokinetic Study in Normal and Sepsis Rats In Vivo and In Vitro.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Liquid; COVID-19; Drugs, Chinese Herbal; Glucosides; Rats; Reproducibility of Results; Sepsis; Tandem Mass Spectrometry | 2023 |
Pharmacokinetic characteristics of emodin in polygoni Multiflori Radix Praeparata.
Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Emodin; Glycosides; Polygonum; Rats; Rats, Sprague-Dawley | 2023 |
UGTs-mediated metabolic interactions contribute to enhanced anti-inflammation activity of Jinhongtang.
Topics: Animals; Anti-Inflammatory Agents; COVID-19; Emodin; Humans; Lipopolysaccharides; Mice; Rats; Sepsis | 2023 |
Anti-Psoriatic Effect of
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Emodin; Interleukin-17; Mice; Psoriasis; Rheum | 2022 |
Soluble Protein Content, Bioactive Compounds and the Antioxidant Activity in Seeds of Ten Rheum tanguticum Lines from Qinghai-Tibet Plateau.
Topics: Anthraquinones; Antioxidants; Emodin; Rheum; Seeds; Tibet | 2023 |
Prediction and verification of the active ingredients and potential targets of Erhuang Quzhi Granules on non-alcoholic fatty liver disease based on network pharmacology.
Topics: Animals; Drugs, Chinese Herbal; Emodin; Lipids; Mice; Molecular Docking Simulation; Network Pharmacology; NF-kappa B; Non-alcoholic Fatty Liver Disease; Tumor Necrosis Factor-alpha | 2023 |
Active ingredients of Erhuang Quzhi Granules for treating non-alcoholic fatty liver disease based on the NF-κB/NLRP3 pathway.
Topics: Animals; Curcumin; Emodin; Inflammasomes; Molecular Docking Simulation; Molecular Structure; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Non-alcoholic Fatty Liver Disease | 2023 |