Page last updated: 2024-09-03

rhein-9-anthrone and dinoprostone

rhein-9-anthrone has been researched along with dinoprostone in 5 studies

Compound Research Comparison

Studies
(rhein-9-anthrone)
Trials
(rhein-9-anthrone)
Recent Studies (post-2010)
(rhein-9-anthrone)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
240229,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomyrhein-9-anthrone (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Witte, P; Geboes, K; Lemli, J; Nijs, G1
Kuwano, S; Miyawaki, Y; Nishikawa, A; Yagi, T; Yamauchi, K1
de Witte, P; Lemli, J; Nijs, G1
Horiyama, S; Kuwano, S; Miyawaki, Y; Nishikawa, A; Yagi, T; Yamauchi, K1
Ikarashi, N; Ishii, M; Kon, R; Kusunoki, Y; Machida, Y; Nagoya, C; Ochiai, W; Sugita, K; Sugiyama, K; Takayama, T; Ueda, H1

Other Studies

5 other study(ies) available for rhein-9-anthrone and dinoprostone

ArticleYear
Influence of rhein anthrone and rhein on small intestine transit rate in rats: evidence of prostaglandin mediation.
    European journal of pharmacology, 1992, Aug-06, Volume: 218, Issue:2-3

    Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Dinoprostone; Dose-Response Relationship, Drug; Gastrointestinal Transit; Intestine, Small; Male; Rats; Rats, Inbred Strains; Senna Extract; Sennosides; Time Factors

1992
Suppression of the purgative action of rhein anthrone, the active metabolite of sennosides A and B, by indomethacin in rats.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:5

    Topics: Animals; Anthracenes; Anthraquinones; Cathartics; Colon; Diarrhea; Dinoprostone; Electrolytes; Female; Gastrointestinal Transit; Indomethacin; Mucus; Rats; Rats, Inbred Strains; Senna Extract; Sennosides; Water

1991
A rapid method for the estimation of prostaglandin E2 in intestinal tissues using fluorescence derivatization.
    Prostaglandins, 1991, Volume: 42, Issue:5

    Topics: Animals; Anthracenes; Anthraquinones; Chromatography, Thin Layer; Densitometry; Dinoprostone; Intestine, Small; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Staining and Labeling

1991
Prostaglandin E2-mediated stimulation of mucus synthesis and secretion by rhein anthrone, the active metabolite of sennosides A and B, in the mouse colon.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:8

    Topics: Animals; Anthracenes; Colon; Diarrhea; Dinoprostone; Female; Mice; Mucus

1990
Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract.
    Journal of ethnopharmacology, 2014, Feb-27, Volume: 152, Issue:1

    Topics: Animals; Anthracenes; Aquaporin 3; Cell Line; Colon; Colonic Neoplasms; Diarrhea; Dinoprostone; HT29 Cells; Humans; Indomethacin; Intestinal Mucosa; Laxatives; Macrophage Activation; Male; Rats; Rats, Wistar; Rheum; Senna Extract; Sennosides

2014