retinol has been researched along with crocin in 61 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.64) | 18.7374 |
| 1990's | 2 (3.28) | 18.2507 |
| 2000's | 8 (13.11) | 29.6817 |
| 2010's | 41 (67.21) | 24.3611 |
| 2020's | 9 (14.75) | 2.80 |
| Authors | Studies |
|---|---|
| Bors, W; Erben-Russ, M; Michel, C; Saran, M | 1 |
| Abe, K; Saito, H; Shoyama, Y; Sugiura, M | 1 |
| Kwan, YW; Li, N; Lin, G; Min, ZD | 1 |
| Alonso, GL; Blázquez, I; Carmona, M; Díaz-Plaza, EM; Ordoudi, SA; Tsimidou, MZ; Zalacain, A | 1 |
| Asai, A; Nagao, A; Nakano, T; Takahashi, M | 1 |
| Baek, NI; Kim, DH; Lee, IA; Lee, JH | 1 |
| Eyanagi, R; Fujiwara, M; Iwasaki, K; Mishima, K; Ochiai, T; Shimeno, H; Shoyama, Y; Soeda, S; Tanaka, H; Toda, A | 1 |
| Bathaie, SZ; Bolhasani, A; Hoshyar, R; Moosavi-Movahedi, AA; Ranjbar, B; Sabouni, F | 1 |
| Hellenbrand, N; Hensel, A; Lechtenberg, M; Niehues, M; Schepmann, D; Wünsch, B | 1 |
| Li, GL; Li, L; Pang, Z; Xiao, YQ; Zhang, C | 1 |
| Befani, CD; Koliakos, GG; Nenadis, N; Ordoudi, SA; Tsimidou, MZ | 1 |
| Alonso, GL; Anastasaki, EG; Carmona, M; Kanakis, CD; Maggi, L; Pappas, C; Polissiou, MG; Zalacain, A | 1 |
| Cho, KH; Hong, JW; Jung, HJ; Jung, WS; Kang, I; Lee, EH; Lee, JY; Min, BD; Nam, KN; Park, JH; Park, SU; Park, YM | 1 |
| Chen, Y; Liu, SJ; Yang, ZL; Zhang, LH; Zhang, XT | 1 |
| Aritake, K; Huang, ZL; Masaki, M; Shoyama, Y; Tanaka, H; Urade, Y | 1 |
| Inukai, T; Mizukami, H; Nagatoshi, M; Nagatsu, A; Owaki, M; Sota, M; Terasaka, K | 1 |
| Hosseinzadeh, H; Nassiri-Asl, M | 1 |
| Galvin, K; Kyriakoudi, A; O'Brien, NM; O'Callaghan, YC; Tsimidou, MZ | 1 |
| Ahrazem, O; Gómez Gómez, L; Granell, A; Rambla, JL; Rubio Moraga, A | 1 |
| Hensel, A; Lautenschläger, M; Lechtenberg, M; Sendker, J | 1 |
| Allmaier, G; Koulakiotis, NS; Pittenauer, E; Tsarbopoulos, A | 1 |
| Bathaie, SZ; Farajzade, A; Hoshyar, R | 1 |
| Kim, SC; Kim, SH; Lee, JM; Lee, PC; Park, CB | 1 |
| Alonso, GL; Carmona, M; D'Alessandro, AM; Di Cesare, E; Festuccia, C; Gravina, GL; Jannini, EA; Lenzi, A; Llorens, S; Mancini, A; Scarsella, L; Tatone, C | 1 |
| Brandt, S; Düfer, M; Galla, HJ; Hensel, A; Hüwel, S; Lautenschläger, M; Riehemann, K; Sendker, J | 1 |
| Broadhead, GK; Chang, A; Grigg, J; McCluskey, P | 1 |
| Alonso, GL; Carmona, M; D'Alessandro, AM; Llorens, S; Mancini, A; Nava, E; Serrano-Díaz, J | 1 |
| Huang, ZQ; Jiang, SJ; Li, HN; Li, SH; Li, Y; Ling, Y; Ren, ZQ; Zhang, F; Zhang, Y; Zhou, WE | 1 |
| Dawalbhakta, M; Telang, M | 1 |
| Ahrazem, O; Diretto, G; Gómez-Gómez, L; Molina, RV; Pallotti, C; Parra-Vega, V; Prieto, A; Rivas-Sendra, A; Rubio-Moraga, Á; Seguí-Simarro, JM | 1 |
| Aa, J; Chen, T; Fei, F; Feng, S; Geng, J; Huang, J; Li, S; Sun, R; Wang, G; Wang, J; Wang, P; Yang, N; Yu, X; Zhang, Y; Zhao, Y; Zhen, L; Zhu, X; Zhu, Y | 1 |
| Bathaie, SZ; Jafarisani, M; Mousavi, MF | 1 |
| Khan, TH; Patel, S; Sarwat, M | 1 |
| Hosseinzadeh, H; Rameshrad, M; Razavi, BM | 1 |
| Ahrazem, O; Argandoña, J; Diretto, G; Gómez-Gómez, L; Granell, A; Julve, JM; Orzáez, D; Rubio-Moraga, Á | 1 |
| Hosseini, A; Hosseinzadeh, H; Razavi, BM | 1 |
| Hayakawa, T; Hori, S; Inoue, E; Masui, R; Shimizu, Y; Sudoh, K; Tsubonoya, T | 1 |
| Alonso Salinas, GL; Alonso, GL; Chaouqi, S; Jiménez-Monreal, AM; José Bagur, M; Llorens, S; Martínez-Tomé, M | 1 |
| Avan, A; Ferns, GA; Hassanian, SM; Kermanshahi, B; Kermanshahi, F; Khazaei, M; Khorasanchi, Z; Parizadeh, MR; Ryzhikov, M; Shafiee, M | 1 |
| Al-Babili, S; Aprea, G; Azad, NH; Demurtas, OC; Diretto, G; Ferrante, P; Frigerio, L; Frusciante, S; Giuliano, G; Mi, J; Pietrella, M; Romano, E; Taddei, AR | 1 |
| Dalla, C; Gikas, E; Karkoula, E; Kokras, N; Lemonakis, N; Skaltsounis, AL; Tsarbopoulos, A | 1 |
| Arzi, L; Hoshyar, R; Jafarzadeh, N; Riazi, G; Sadeghizadeh, M | 2 |
| D'Archivio, AA; Di Donato, F; Foschi, M; Maggi, MA; Ruggieri, F | 1 |
| Amel Farzad, S; Ghasim, H; Hashemi, M; Kalalinia, F; Pishavar, E; Ramezani, M | 1 |
| Brunetti, L; Chiavaroli, A; Ferrante, C; Leone, S; Leporini, L; Menghini, L; Orlando, G; Recinella, L | 1 |
| Cardile, V; Crascì, L; Graziano, ACE; Musumeci, T; Panico, AM; Puglia, C; Puglisi, G; Raciti, G; Salerno, L; Santonocito, D | 1 |
| Angelis, A; Gikas, E; Halabalaki, M; Karkoula, E; Koulakiotis, NS; Skaltsounis, AL; Tsarbopoulos, A | 1 |
| Chu, J; Ding, F; He, B; Liu, F; Shao, W; Wu, B | 1 |
| Colapietro, A; D'Alessandro, AM; Festuccia, C; Mancini, A | 1 |
| Bai, C; Chen, Y; Deng, L; Du, L; Hu, Y; Li, X; Liu, X; Liu, Y; Sun, L; Wang, W; Wang, Z; Xia, Q; Yin, T; Zhang, H | 1 |
| Brown, J; Heitmar, R; Kyrou, I | 1 |
| Bi, C; Dai, L; He, P; Sun, Y; Wang, W; Ye, L; Zhang, X; Zhao, D; Zheng, J | 1 |
| Ayanmanesh, M; Csupor, D; Horváth, A; Khamushi, A; Kiss, T; Mahmoodi Sourestani, M; Mottaghipisheh, J; Tóth, B | 1 |
| Arab, FL; Mahmoudi, M; Nikkhah, K; Rastin, M; Tabasi, NS; Yousefi, F | 1 |
| Chu, X; Guan, S; Jin, W; Liang, Y; Wang, H; Xue, Y; Zhang, J; Zhang, Y | 1 |
| Bisti, S; Maggi, MA; Picco, C | 1 |
| Cerdá-Bernad, D; Frutos, MJ; Pastor, JJ; Valero-Cases, E | 1 |
| Hosseini, SM; Khodaverdi, E; Mehri, S; Mohajeri, SA; Sepahi, S; Soheili, ZS; Tavakkol-Afshari, J | 1 |
| Bordes, A; Lemée, L; Suchareau, M | 1 |
| Emami, SA; Jafari, F; Javadi, B; Salmasi, Z; Tayarani-Najaran, Z; Tayarani-Najjaran, M | 1 |
13 review(s) available for retinol and crocin
| Article | Year |
|---|---|
Avicenna's (Ibn Sina) the Canon of Medicine and saffron (Crocus sativus): a review.
Topics: Carotenoids; Cosmetics; Crocus; Cyclohexenes; Herbal Medicine; History, Medieval; Incunabula as Topic; Plant Extracts; Terpenes; Vitamin A | 2013 |
A review of the chemistry and uses of crocins and crocetin, the carotenoid natural dyes in saffron, with particular emphasis on applications as colorants including their use as biological stains.
Topics: Animals; Carotenoids; Coloring Agents; Crocus; Flowers; Humans; Plant Extracts; Vitamin A | 2014 |
Efficacy and Safety of Saffron Supplementation: Current Clinical Findings.
Topics: Affect; Animals; Antioxidants; Cardiovascular System; Carotenoids; Clinical Trials as Topic; Cognition; Crocus; Cyclohexenes; Disease Models, Animal; Humans; Oxidative Stress; Phytotherapy; Plant Preparations; Reproduction; Terpenes; Vision, Ocular; Vitamin A; Zeaxanthins | 2016 |
Patents on Therapeutic and Cosmetic Applications of Bioactives of Crocus Sativus L. and their Production through Synthetic Biology Methods: A Review.
Topics: Animals; Biological Factors; Carotenoids; Cosmeceuticals; Crocus; Cyclohexenes; Databases, Factual; Humans; Metabolic Diseases; Nervous System Diseases; Patents as Topic; Plant Extracts; Synthetic Biology; Terpenes; Vitamin A | 2017 |
Mechanism behind the anti-tumour potential of saffron (Crocus sativus L.): The molecular perspective.
Topics: Animals; Antineoplastic Agents; Carotenoids; Crocus; Cyclohexenes; Humans; Terpenes; Vitamin A | 2017 |
Saffron and its derivatives, crocin, crocetin and safranal: a patent review.
Topics: Animals; Carotenoids; Crocus; Cyclohexenes; Drug Design; Humans; Patents as Topic; Plant Extracts; Terpenes; Vitamin A | 2018 |
Pharmacokinetic Properties of Saffron and its Active Components.
Topics: Animals; Carotenoids; Crocus; Humans; Vitamin A | 2018 |
Saffron: An Old Medicinal Plant and a Potential Novel Functional Food.
Topics: Antidepressive Agents; Antineoplastic Agents; Antioxidants; Carotenoids; Color; Crocus; Cyclohexenes; Functional Food; Glucosides; Humans; Phytochemicals; Plants, Medicinal; Spices; Terpenes; Vitamin A | 2017 |
Crocus sativus a natural food coloring and flavoring has potent anti-tumor properties.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carotenoids; Cell Cycle; Crocus; Cyclohexenes; Female; Food Coloring Agents; Glucosides; Humans; Male; Secondary Metabolism; Terpenes; Vitamin A | 2018 |
Phytotherapic use of the Crocus sativus L. (Saffron) and its potential applications: A brief overview.
Topics: Alzheimer Disease; Animals; Atherosclerosis; Carotenoids; Crocus; Cyclohexenes; Depression; Glucosides; Humans; Neoplasms; Phytotherapy; Plant Extracts; Sexual Dysfunction, Physiological; Terpenes; Vitamin A | 2018 |
Crocetin and Crocin from Saffron in Cancer Chemotherapy and Chemoprevention.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Carotenoids; Chemoprevention; Crocus; Humans; Neoplasms; Vitamin A | 2019 |
Saffron (
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Carotenoids; Crocus; Eye; Eye Diseases; Humans; Neuroprotective Agents; Phytotherapy; Plant Extracts; Vitamin A | 2019 |
Saffron bioactives crocin, crocetin and safranal: effect on oxidative stress and mechanisms of action.
Topics: Antioxidants; Carotenoids; Crocus; Cyclohexenes; Oxidative Stress; Plant Extracts; Terpenes; Vitamin A | 2022 |
48 other study(ies) available for retinol and crocin
| Article | Year |
|---|---|
Determination of sulfite radical (SO.3-) reaction rate constants by means of competition kinetics.
Topics: Carotenoids; Fatty Acids, Unsaturated; Free Radicals; Glutathione; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Phenols; Quercetin; Sulfites; Vitamin A | 1987 |
Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in vivo.
Topics: Animals; Carotenoids; Ethanol; Hippocampus; Long-Term Potentiation; Male; Memory; Plant Extracts; Rats; Rats, Wistar; Vitamin A | 1994 |
Simultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatography.
Topics: Carotenoids; Chromatography, High Pressure Liquid; Liliaceae; Spectrophotometry, Ultraviolet; Vitamin A | 1999 |
Screening method for the detection of artificial colours in saffron using derivative UV-Vis spectrometry after precipitation of crocetin.
Topics: Antioxidants; Carotenoids; Chemical Precipitation; Condiments; Crocus; Food Coloring Agents; Food Contamination; Hydrogen-Ion Concentration; Hydrolysis; Spectrum Analysis; Spices; Ultraviolet Rays; Vitamin A | 2005 |
Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice.
Topics: Administration, Oral; Animals; Carotenoids; Glucuronides; Hydrolysis; Intestinal Absorption; Male; Mice; Mice, Inbred ICR; Vitamin A | 2005 |
Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite Crocetin.
Topics: Animals; Body Weight; Carotenoids; Cholesterol, LDL; Diet; Fruit; Gardenia; Hypercholesterolemia; Hypolipidemic Agents; Lipase; Lipids; Male; Mice; Mice, Inbred ICR; Organ Size; Triglycerides; Vitamin A | 2005 |
Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo.
Topics: Animals; Antioxidants; Brain Infarction; Carotenoids; Caspase 3; Cell Hypoxia; Cell Survival; Crocus; Cyclohexenes; Disease Models, Animal; Glucosides; Glutamate-Cysteine Ligase; Glutathione; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Membrane Lipids; Mice; Molecular Structure; Neurons; Neuroprotective Agents; PC12 Cells; Rats; Structure-Activity Relationship; Terpenes; Time Factors; Vitamin A | 2007 |
Interaction of saffron carotenoids as anticancer compounds with ctDNA, Oligo (dG.dC)15, and Oligo (dA.dT)15.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carotenoids; Cattle; Circular Dichroism; Crocus; DNA; Molecular Conformation; Molecular Structure; Oligodeoxyribonucleotides; Poly dA-dT; Spectrometry, Fluorescence; Vitamin A | 2007 |
Quality and functionality of saffron: quality control, species assortment and affinity of extract and isolated saffron compounds to NMDA and sigma1 (sigma-1) receptors.
Topics: Carotenoids; Crocus; Cyclohexanones; Cyclohexenes; Flowers; Glucosides; Plant Extracts; Quality Control; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Reference Standards; Sigma-1 Receptor; Terpenes; Vitamin A | 2008 |
[Content comparison of diterpenoid pigments in different processed products of Gardenia jasminoides].
Topics: Carotenoids; Chromatography, High Pressure Liquid; Diterpenes; Drugs, Chinese Herbal; Gardenia; Reproducibility of Results; Vitamin A | 2008 |
Further examination of antiradical properties of Crocus sativus stigmas extract rich in crocins.
Topics: Antioxidants; Carotenoids; Crocus; Flowers; Free Radical Scavengers; Humans; Monocytes; Plant Extracts; Reactive Oxygen Species; Vitamin A | 2009 |
Quantification of crocetin esters in saffron (Crocus sativus L.) using Raman spectroscopy and chemometrics.
Topics: Calibration; Carotenoids; Chromatography, High Pressure Liquid; Color; Crocus; Esters; Least-Squares Analysis; Quality Control; Reproducibility of Results; Spectrum Analysis, Raman; Vitamin A | 2010 |
Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Brain; Carotenoids; Cytokines; Interferon-gamma; Lipopolysaccharides; Male; Mice; Microglia; Neurons; NF-kappa B; Nitric Oxide; Peptide Fragments; Rats; Reactive Oxygen Species; Vitamin A | 2010 |
[Determination of geniposide, crocin and crocetin in different processing products of fructus gardeniae by HPLC-ELSD].
Topics: Carotenoids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Gardenia; Iridoids; Quality Control; Reproducibility of Results; Technology, Pharmaceutical; Vitamin A | 2011 |
Crocin promotes non-rapid eye movement sleep in mice.
Topics: Administration, Oral; Animals; Carotenoids; Crocus; Dose-Response Relationship, Drug; Electroencephalography; Injections, Intraperitoneal; Mice; Sleep Stages; Sleep, REM; Time; Vitamin A | 2012 |
UGT75L6 and UGT94E5 mediate sequential glucosylation of crocetin to crocin in Gardenia jasminoides.
Topics: Alkylation; Carotenoids; Cells, Cultured; Dietary Supplements; Food Coloring Agents; Fruit; Gardenia; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucosides; Glucosyltransferases; Isoenzymes; Phylogeny; Plant Proteins; Recombinant Proteins; RNA, Messenger; Seedlings; Substrate Specificity; Uridine Diphosphate Glucose; Vitamin A | 2012 |
Changes in total and individual crocetin esters upon in vitro gastrointestinal digestion of saffron aqueous extracts.
Topics: Animals; Antioxidants; Carotenoids; Cell Survival; Comet Assay; Crocus; Digestion; Esterification; Fruit; Gardenia; Gastric Mucosa; Humans; Intestinal Mucosa; Models, Biological; Molecular Structure; Monocytes; Mouth Mucosa; Pancreatic Juice; Plant Extracts; Spices; U937 Cells; Vitamin A | 2013 |
Crocins with high levels of sugar conjugation contribute to the yellow colours of early-spring flowering crocus tepals.
Topics: beta Carotene; Carotenoids; Color; Crocus; Flowers; Gene Expression; Geranylgeranyl-Diphosphate Geranylgeranyltransferase; Glucose; Glucosyltransferases; Phylogeny; Plant Proteins; Rhamnose; Spectrometry, Mass, Electrospray Ionization; Spices; Tandem Mass Spectrometry; Vitamin A | 2013 |
Effective isolation protocol for secondary metabolites from saffron: semi-preparative scale preparation of crocin-1 and trans-crocetin.
Topics: Antidepressive Agents; Carotenoids; Crocus; Flowers; Neuroprotective Agents; Phytotherapy; Plant Extracts; Secondary Metabolism; Vitamin A | 2014 |
In-chain neutral hydrocarbon loss from crocin apocarotenoid ester glycosides and the crocetin aglycon (Crocus sativus L.) by ESI-MS(n) (n=2, 3).
Topics: Carotenoids; Crocus; Flowers; Glycosylation; Hydrocarbons; Models, Molecular; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Vitamin A | 2013 |
Proposed cytotoxic mechanisms of the saffron carotenoids crocin and crocetin on cancer cell lines.
Topics: Carotenoids; Cell Line, Tumor; Crocus; Cytotoxins; Female; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; NF-E2-Related Factor 2; Reactive Oxygen Species; Vitamin A | 2014 |
Antitumor effects of saffron-derived carotenoids in prostate cancer cell models.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cadherins; Carotenoids; Cell Line; Cell Line, Tumor; Cell Transdifferentiation; Crocus; Epithelial-Mesenchymal Transition; Humans; Male; Mice; Mice, Nude; NIH 3T3 Cells; Plant Extracts; Prostatic Neoplasms; Vitamin A | 2014 |
Intestinal formation of trans-crocetin from saffron extract (Crocus sativus L.) and in vitro permeation through intestinal and blood brain barrier.
Topics: Animals; Biological Availability; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Carotenoids; Crocus; Glycosylation; Humans; Intestinal Absorption; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Plant Extracts; Swine; Vitamin A | 2015 |
Effects of Crocetin Esters and Crocetin from Crocus sativus L. on Aortic Contractility in Rat Genetic Hypertension.
Topics: Animals; Aorta; Carotenoids; Crocus; Disease Models, Animal; Esters; Hypertension; Male; Muscle, Smooth, Vascular; Plant Extracts; Rats; Rats, Inbred SHR; Vitamin A | 2015 |
Determination of gardenia yellow colorants in soft drink, pastry, instant noodles with ultrasound-assisted extraction by high performance liquid chromatography-electrospray ionization tandem mass spectrum.
Topics: Beijing; Carbonated Beverages; Carotenoids; Chromatography, High Pressure Liquid; Coloring Agents; Food Analysis; Gardenia; Iridoids; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Vitamin A | 2016 |
Unraveling Massive Crocins Transport and Accumulation through Proteome and Microscopy Tools during the Development of Saffron Stigma.
Topics: Carotenoids; Crocus; Gene Expression Regulation, Plant; Plant Proteins; Plastids; Proteome; Terpenes; Vitamin A | 2017 |
Sensitive analysis and simultaneous assessment of pharmacokinetic properties of crocin and crocetin after oral administration in rats.
Topics: Administration, Oral; Animals; Biological Availability; Carotenoids; Chromatography, Liquid; Female; Injections, Intravenous; Linear Models; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Vitamin A | 2017 |
Saffron carotenoids (crocin and crocetin) binding to human serum albumin as investigated by different spectroscopic methods and molecular docking.
Topics: Binding Sites; Carotenoids; Circular Dichroism; Crocus; Fluorescence; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Vitamin A | 2018 |
Evolutionarily distinct carotenoid cleavage dioxygenases are responsible for crocetin production in Buddleja davidii.
Topics: Buddleja; Carotenoids; Computer Simulation; Dioxygenases; Escherichia coli; Evolution, Molecular; Flowers; Gene Expression Regulation, Plant; Phylogeny; Plant Proteins; Recombinant Fusion Proteins; Vitamin A; Zeaxanthins | 2017 |
Effects of saffron and its constituents, crocin-1, crocin-2, and crocetin on α-synuclein fibrils.
Topics: alpha-Synuclein; Carotenoids; Crocus; Plant Extracts; Vitamin A | 2018 |
Candidate Enzymes for Saffron Crocin Biosynthesis Are Localized in Multiple Cellular Compartments.
Topics: Aldehyde Dehydrogenase; Carotenoids; Crocus; Gene Expression Profiling; Gene Expression Regulation, Plant; Glycosylation; Glycosyltransferases; Green Fluorescent Proteins; Immunohistochemistry; Microscopy, Confocal; Nicotiana; Organ Specificity; Plant Proteins; Plants, Genetically Modified; Vitamin A | 2018 |
Trans-crocin 4 is not hydrolyzed to crocetin following i.p. administration in mice, while it shows penetration through the blood brain barrier.
Topics: Animals; Biological Availability; Biological Transport; Blood-Brain Barrier; Brain Chemistry; Carotenoids; Chromatography, High Pressure Liquid; Male; Mice; Vitamin A | 2018 |
A Comparative Study on Anti-Invasion, Antimigration, and Antiadhesion Effects of the Bioactive Carotenoids of Saffron on 4T1 Breast Cancer Cells Through Their Effects on Wnt/β-Catenin Pathway Genes.
Topics: Animals; beta Catenin; Breast Neoplasms; Carotenoids; Cell Adhesion; Cell Movement; Crocus; Female; Humans; Mice; Neoplasm Metastasis; Plant Extracts; Tumor Cells, Cultured; Vitamin A; Wnt Signaling Pathway | 2018 |
UHPLC Analysis of Saffron (
Topics: Carotenoids; Chromatography, High Pressure Liquid; Coloring Agents; Crocus; Esters; Glucosides; Mass Spectrometry; Neural Networks, Computer; Plant Extracts; Tracheophyta; Vitamin A | 2018 |
Comparison of the effect of crocin and crocetin, two major compounds extracted from saffron, on osteogenic differentiation of mesenchymal stem cells.
Topics: Animals; Carotenoids; Cell Differentiation; Cells, Cultured; Crocus; Male; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Plant Extracts; Rats; Rats, Wistar; Vitamin A | 2018 |
Nanotechnological Approach to Increase the Antioxidant and Cytotoxic Efficacy of Crocin and Crocetin.
Topics: Antineoplastic Agents; Antioxidants; Biological Availability; Carotenoids; Cell Line, Tumor; Cytotoxins; Drug Delivery Systems; Humans; Nanoparticles; Vitamin A | 2019 |
Rapid isolation and characterization of crocins, picrocrocin, and crocetin from saffron using centrifugal partition chromatography and LC-MS.
Topics: Acetates; Butanols; Carotenoids; Centrifugation; Chromatography, Liquid; Crocus; Cyclohexenes; Ethanol; Glucosides; Heptanes; Mass Spectrometry; Molecular Structure; Solvents; Terpenes; Vitamin A; Water | 2018 |
Efficient Synthesis of Crocins from Crocetin by a Microbial Glycosyltransferase from Bacillus subtilis 168.
Topics: Bacillus subtilis; Bacterial Proteins; Carotenoids; Glycosylation; Glycosyltransferases; Vitamin A | 2018 |
Comparative anti-arthritic investigation of iridoid glycosides and crocetin derivatives from Gardenia jasminoides Ellis in Freund's complete adjuvant-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carotenoids; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Freund's Adjuvant; Gardenia; Iridoid Glycosides; Iridoids; Male; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vitamin A | 2019 |
Construction of Escherichia coli cell factories for crocin biosynthesis.
Topics: Biosynthetic Pathways; Carotenoids; Crocus; Dioxygenases; Escherichia coli; Gardenia; Genes, Plant; Glycosyltransferases; Metabolic Engineering; Plant Proteins; Vitamin A | 2019 |
Anti-metastatic properties of a potent herbal combination in cell and mice models of triple negative breast cancer.
Topics: Animals; Carotenoids; Cell Line; Cell Proliferation; Herbal Medicine; Humans; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Triple Negative Breast Neoplasms; Vitamin A | 2020 |
Comprehensive chemotaxonomic analysis of saffron crocus tepal and stamen samples, as raw materials with potential antidepressant activity.
Topics: Antidepressive Agents; Carotenoids; Chromatography, High Pressure Liquid; Crocus; Cyclohexenes; Flavonoids; Flowers; Glucosides; Kaempferols; Monosaccharides; Plant Extracts; Quercetin; Terpenes; Vitamin A | 2020 |
Comparative assessment of immunomodulatory, proliferative, and antioxidant activities of crocin and crocetin on mesenchymal stem cells.
Topics: Antioxidants; Apoptosis; Carotenoids; Cell Proliferation; Cells, Cultured; Crocus; Humans; Immunomodulation; Mesenchymal Stem Cells; Multiple Sclerosis; Nitric Oxide; Plant Extracts; Vitamin A | 2021 |
Inhibitory effects of four active components in saffron on human ether-a-go-go-related gene (hERG) K+ currents.
Topics: Arrhythmias, Cardiac; Carotenoids; Crocus; Cyclohexenes; ERG1 Potassium Channel; Glucosides; Humans; Phytochemicals; Terpenes; Vitamin A | 2020 |
Saffron: Chemical Composition and Neuroprotective Activity.
Topics: Adenosine Triphosphate; Animals; Calcium; Carotenoids; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Crocus; Disease Models, Animal; Flowers; HEK293 Cells; Humans; Light; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Plant Extracts; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Retina; Retinal Degeneration; Vitamin A | 2020 |
Retinoprotective Effects Of Crocin And Crocetin via Anti-Angiogenic Mechanism in High Glucose-Induced Human Retinal Pigment Epithelium Cells.
Topics: Carotenoids; Glucose; Humans; Retinal Pigment Epithelium; Vascular Endothelial Growth Factor A; Vitamin A | 2021 |
Improved quantification method of crocins in saffron extract using HPLC-DAD after qualification by HPLC-DAD-MS.
Topics: Air; Carotenoids; Chromatography, High Pressure Liquid; Crocus; Food Analysis; Food Storage; Light; Mass Spectrometry; Plant Extracts; Vitamin A | 2021 |
Inhibitory effect of saffron, crocin, crocetin, and safranal against adipocyte differentiation in human adipose-derived stem cells.
Topics: Adipocytes; Carotenoids; Cell Differentiation; Crocus; Cyclohexenes; Humans; Mesenchymal Stem Cells; Obesity; Plant Extracts; PPAR gamma; Terpenes; Vitamin A | 2022 |