retinamide and axerophthene

retinamide has been researched along with axerophthene* in 1 studies

Other Studies

1 other study(ies) available for retinamide and axerophthene

Article	Year
HINT predictive analysis of binding between retinol binding protein and hydrophobic ligands. Bioorganic & medicinal chemistry letters, 2000, Sep-18, Volume: 10, Issue:18 The interaction between the retinol binding protein and four ligands was evaluated using HINT, a software based on experimental LogP values of individual atoms. A satisfactory correlation was found between the HINT scores and the experimental dissociation constants of three of the ligands, fenretinide, N-ethylretinamide and all-trans retinol, despite their hydrophobic nature. A prediction is made for the binding affinity of the fourth ligand, axerophtene, not yet determined in solution. Topics: Algorithms; Antineoplastic Agents; Diterpenes; Fenretinide; Humans; Ligands; Models, Molecular; Protein Binding; Retinol-Binding Proteins; Solubility; Tretinoin; Vitamin A	2000

Article

Year

HINT predictive analysis of binding between retinol binding protein and hydrophobic ligands.

Bioorganic & medicinal chemistry letters, 2000, Sep-18, Volume: 10, Issue:18

The interaction between the retinol binding protein and four ligands was evaluated using HINT, a software based on experimental LogP values of individual atoms. A satisfactory correlation was found between the HINT scores and the experimental dissociation constants of three of the ligands, fenretinide, N-ethylretinamide and all-trans retinol, despite their hydrophobic nature. A prediction is made for the binding affinity of the fourth ligand, axerophtene, not yet determined in solution.

Topics: Algorithms; Antineoplastic Agents; Diterpenes; Fenretinide; Humans; Ligands; Models, Molecular; Protein Binding; Retinol-Binding Proteins; Solubility; Tretinoin; Vitamin A

2000