resveratrol has been researched along with stilbenes in 7403 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.01) | 18.7374 |
| 1990's | 125 (1.69) | 18.2507 |
| 2000's | 2043 (27.60) | 29.6817 |
| 2010's | 5040 (68.08) | 24.3611 |
| 2020's | 194 (2.62) | 2.80 |
| Authors | Studies |
|---|---|
| Harima, S; Kageura, T; Matsuda, H; Morikawa, T; Toguchida, I; Yoshikawa, M | 1 |
| Go, ML; Zhang, W | 2 |
| De Mieri, M; Hamburger, M; Hering, S; Jähne, EA; Raith, M; Rueda, DC; Schöffmann, A | 1 |
| Alam, MS; Ismail, T; Khazir, J; Kumar, HM; Qurishi, Y; Sarkar, D; Shafi, S; Srinivas, J | 1 |
| Cheng, KL; Chung, MI; Ko, FN; Lin, CN; Teng, CM | 1 |
| Bieseler, B; Hain, R; Kindl, H; Schröder, G; Stöcker, R | 1 |
| Fassina, G; Froldi, G; Ragazzi, E | 1 |
| Miller, NJ; Rice-Evans, CA | 1 |
| Bernini, W; Bertelli, A; Bertelli, AA; Fregoni, M; Giannessi, D; Giovannini, L; Migliori, M | 1 |
| Diamandis, EP; Goldberg, DM; Hahn, S; Pace-Asciak, CR; Soleas, G | 1 |
| Bi, N; Tang, R; Wei, H; Wen, D | 1 |
| Kimura, Y; Kubo, M; Okuda, H | 1 |
| Frankel, EN; Kinsella, JE; Waterhouse, AL | 1 |
| Ashendel, CL; Chang, CJ; Geahlen, RL; Jayasuriya, H; Jayatilake, GS; Koonchanok, NM; Lee, ES; McLaughlin, JL | 1 |
| Mattivi, F | 1 |
| Goldberg, DM | 1 |
| Diamandis, E; Goldberg, DM; Karumanchiri, A; Ng, E; Soleas, G; Tsang, E | 1 |
| Celotti, E; Conte, LS; Ferrarini, R; Zironi, R | 1 |
| Beitz, DC; Engen, RL; Knight, TJ; Lewis, DS; Wilson, T | 1 |
| Diamandis, EP; Goldberg, DM; Hahn, SE; Pace-Asciak, CR; Rounova, O | 1 |
| Chen, CK; Pace-Asciak, CR | 1 |
| Cerletti, C; de Gaetano, G; Rotilio, D; Rotondo, S | 1 |
| Beecher, CW; Cai, L; Farnsworth, NR; Fong, HH; Jang, M; Kinghorn, AD; Mehta, RG; Moon, RC; Pezzuto, JM; Slowing, KV; Thomas, CF; Udeani, GO | 1 |
| Bavaresco, L; Bernini, W; Bertelli, A; Bertelli, AA; Fregoni, M; Giovannini, L; Migliori, M | 1 |
| Miyazawa, M; Nakamura, S; Uenobe, F | 1 |
| Bertelli, A; Bertelli, AA; Giovannini, L; Stradi, R; Tillement, JP | 1 |
| Diamandis, EP; Goldberg, DM; Soleas, GJ | 2 |
| Bertelli, A; Bertelli, AA; Giovannini, L; Stradi, R; Tillement, JP; Urien, S | 2 |
| Chanvitayapongs, S; Draczynska-Lusiak, B; Sun, AY | 1 |
| Belguendouz, L; Fremont, L; Linard, A | 1 |
| Bellini, B; Miglierini, G; Orsini, F; Pelizzoni, F | 1 |
| Bonard, EC | 1 |
| Chen, YM; Cheng, Y; James-Kracke, M; Sun, AY; Wixom, P | 1 |
| Chien, PY; Gehm, BD; Jameson, JL; McAndrews, JM | 1 |
| Okuda, T; Sato, M; Suzuki, Y; Yokotsuka, K | 1 |
| Blache, D; Durand, P; Lesgards, G; Loreau, N; Rustan, I | 1 |
| Lariccia, J; Nair, MG; Turrens, JF | 1 |
| Elleingand, E; Fontecave, M; Gerez, C; Guittet, O; Lepoivre, M | 1 |
| Mgbonyebi, OP; Russo, IH; Russo, J | 1 |
| Chang, IM; Choi, EJ; Kang, SH; Kim, Y; Min, KR; Ryu, SY; Shin, NH | 1 |
| Chen, YM; Draczynska-Lusiak, B; Sun, AY | 1 |
| Kim, Y; Lee, H; Min, KR; Ryu, SY; Shin, NH | 1 |
| Inoue, M; Kawada, N; Kuroki, T; Seki, S | 1 |
| Belguendouz, L; Frémont, L; Gozzelino, MT | 1 |
| Celardo, A; Cerletti, C; de Gaetano, G; Evangelista, V; Manarini, S; Rajtar, G; Rotillo, D; Rotondo, S | 1 |
| Kopp, P | 1 |
| Chawdhury, SH; Clément, MV; Hirpara, JL; Pervaiz, S | 1 |
| Chung, WJ; Dannenberg, AJ; Inoue, H; Jang, M; Michaluart, P; Pezzuto, JM; Subbaramaiah, K; Tanabe, T; Telang, N | 1 |
| Borriello, A; Cucciolla, V; Galletti, P; Manna, C; Pietra, VD; Racioppi, L; Ragione, FD; Soldati, G; Zappia, V | 1 |
| Cichewicz, RH; Kouzi, SA | 1 |
| Johnson, JL; Maddipati, KR | 1 |
| Bertelli, A; Bertelli, AA; Giovannini, L; Gozzini, A | 1 |
| Bertelli, A; Bertelli, AE; Bonfrate, M; Corsi, MM; De Caterina, R; Ferrara, F; Ferrero, ME; Fulgenzi, A; Giovannini, L; Pellegatta, F | 1 |
| Bertelli, A; Bertelli, AA; Corsi, MM; Ferrero, ME; Fulgenzi, A; Pellegatta, F | 1 |
| Ciolino, HP; Daschner, PJ; Yeh, GC | 1 |
| Fukuhara, K; Miyata, N | 1 |
| Evans, GL; Maran, A; Sibonga, JD; Turner, RT; Zhang, M | 1 |
| Ikeda, K; Kawai, Y; Mizutani, K; Yamori, Y | 3 |
| Argilés, JM; Baccino, FM; Carbó, N; Costelli, P; López-Soriano, FJ | 1 |
| Pendurthi, UR; Rao, LV; Williams, JT | 1 |
| de la Torre-Boronat, MC; Juan, ME; Lamuela-Raventós, RM; Planas, JM | 1 |
| Chang, IM; Jang, DS; Kang, BS; Kim, Y; Min, KR; Ryu, SY | 1 |
| Bertelli, A; Bertelli, AA; Gozzini, A; Stella, S; Stradi, R | 1 |
| Dong, Z; Goranson, A; Huang, C; Ma, WY | 1 |
| Koop, DR; Wadsworth, TL | 1 |
| Lin, JK; Lin-Shiau, SY; Tsai, SH | 1 |
| ElAttar, TM; Virji, AS | 1 |
| Jäger, U; Nguyen-Duong, H | 1 |
| Goodman, DW; Klironomos, G; Neirinck, L; Vachereau, A; Zhu, Z | 1 |
| Lu, R; Serrero, G | 2 |
| Daniel, O; Frischknecht, P; Meier, MS; Schlatter, J | 1 |
| Cheong, H; Kim, KM; Ryu, SY | 1 |
| Bertelli, AA; Miloso, M; Nicolini, G; Tredici, G | 1 |
| Hsieh, TC; Wu, JM | 4 |
| El-Mowafy, AM; White, RE | 1 |
| Darzynkiewicz, Z; Hsieh, TC; Juan, G; Wu, JM | 1 |
| Benedetti, A; Bolognini, L; Casini, A; D'Ambrosio, L; Di Sario, A; Ferretti, G; Orlandi, F; Ridolfi, F; Salzano, R; Svegliati-Baroni, G | 1 |
| Bertelli, AA | 2 |
| Jang, M; Pezzuto, JM | 2 |
| Mameli, M; Palmieri, L; Ronca, G | 1 |
| Bertelli, A; Bertelli, AA; Morin, C; Tillement, JP; Zini, R | 1 |
| Bertelli, A; Cavaletti, G; Galbiati, S; Miloso, M; Nicolini, G; Tredici, G | 1 |
| Blardi, P; De Lalla, A; Di Perri, T; Volpi, L | 1 |
| Calabrese, G | 1 |
| Bertelli, A; Bertelli, AA; Das, DK; Engelman, RM; Maulik, G; Ray, PS; Sato, M | 1 |
| Cheng, GF; Guo, Y; Wang, WJ; Zhang, JT; Zhong, M; Zhu, XY | 1 |
| Agarwal, S; Hecht, SS; Kenney, PM; Rao, AV; Trushin, N; Upadhyaya, P; Wang, M | 1 |
| Barja, G; Cadenas, S | 1 |
| Backer, JM; Burfeind, P; Darzynkiewicz, Z; Hsieh, TC; Laud, K; Traganos, F; Wu, JM | 1 |
| Belguendouz, L; Delpal, S; Frémont, L | 1 |
| Hurh, YJ; Kang, JY; Kong, G; Lee, E; Lee, SJ; Surh, YJ | 1 |
| Chen, Q; Hsieh, TC; Huang, YZ; Wei, EH; Wu, JM; Zou, JG | 1 |
| Ramirez, VD; Zheng, J | 2 |
| Bowman, ME; Dixon, RA; Ferrer, JL; Jez, JM; Noel, JP | 1 |
| Bertelli, A; Bertelli, AA; Cordis, GA; Das, DK; Maulik, G; Ray, PS | 1 |
| Chun, YJ; Guengerich, FP; Kim, MY | 1 |
| Agrò, AF; Guerrieri, P; Lorenzon, T; MacCarrone, M | 1 |
| Lin, JK; Tsai, SH | 1 |
| Cao, K; Chen, Q; Hsieh, TC; Huang, Y; Wang, N; Wu, JM; Zou, J | 1 |
| Ciolino, HP; Yeh, GC | 2 |
| Casper, RF; Jolivet, A; Milgrom, E; Quesne, M; Rogers, IM; Savouret, JF; Shirota, T | 1 |
| Blackmore, PF; Dobrydneva, Y; Williams, RL | 1 |
| Gottlieb, N | 1 |
| Surh, Y | 1 |
| Albert, L; Kátay, G; Király-Véghely, Z; Németh, ZI; Tyihák, E | 1 |
| Ioannides, CG; O'Brian, CA; Stewart, JR; Ward, NE | 1 |
| Baumgartner, G; Hamilton, G; Hejna, M; Hoffmann, O; Mallinger, R; Raderer, M; Ulsperger, E | 1 |
| DeLucia, AL; Docherty, JJ; Fu, MM; Limperos, RJ; Pokabla, CM; Stiffler, BS | 1 |
| Creasy, L; Gu, X; Kester, A; Zeece, M | 1 |
| Ho, CT; Jin, Y; Wang, M | 1 |
| Ashby, J; Odum, J; Slater, I | 1 |
| Berzas Nevado, JJ; Castañeda Peñalvo, G; Contento Salcedo, AM | 1 |
| Cole, RJ; Sobolev, VS | 1 |
| de La Torre-Boronat, MC; Ibern-Gómez, M; Lamuela-Raventós, RM; Romero-Pérez, AI | 1 |
| Bastow, KF; Iinuma, M; Ito, T; Lee, KH; Ohyama, M; Tanaka, T | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Sliwowski, Z; Stachura, J | 1 |
| de Godos, A; García-García, J; Gómez-Fernández, JC; Micol, V | 1 |
| Mitchell, SH; Young, CY; Zhu, W | 1 |
| García-Barrado, JA; Macías, P; Pinto, MC | 1 |
| Charpentier, C; Deopujari, J; Masih, I; Paul, B | 1 |
| Cichewicz, RH; Hamann, MT; Kouzi, SA | 1 |
| Bagchi, D; Das, DK; Maulik, G; Sato, M | 1 |
| Chung, WJ; Dannenberg, AJ; Michaluart, P; Subbaramaiah, K; Tanabe, T; Telang, N | 1 |
| Bertelli, A; Bertelli, AA; Das, DK; Engelman, RM; Maulik, G; Maulik, N; Ray, PS; Sato, M | 1 |
| Frémont, L | 1 |
| Chen, Y; Ho, CT; Rosen, RT; Vastano, BC; Zhou, Z; Zhu, N | 1 |
| Basly, JP; Chulia, AJ; Habrioux, G; Le Bail, JC; Marre-Fournier, F | 1 |
| Contestabile, A; Virgili, M | 1 |
| Babich, H; Reisbaum, AG; Zuckerbraun, HL | 1 |
| Martinez, J; Moreno, JJ | 1 |
| Couronné, B; Desmoulière, A; Dubuisson, L; Godichaud, S; Krisa, S; Mérillon, JM; Rosenbaum, J | 1 |
| Chapman, RA; Dumaguin, M; Gautam, SC; Janakiraman, N; Xu, YX | 1 |
| Kelly, JW; Klabunde, T; Oza, VB; Petrassi, HM; Raman, P; Sacchettini, JC | 1 |
| Bertelli, A; Bertelli, AA; Corsi, M; Diana, G; Ferrara, F; Ferrero, ME; Fulgenzi, A; Ponti, W | 1 |
| Dinan, L; Keckeis, K; Sarker, SD | 1 |
| Hendrix, KW; McMichael, RW; Sanders, TH | 1 |
| Doyle, PJ; Naderali, EK; Williams, G | 1 |
| Hipskind, JD; Paiva, NL | 1 |
| Cregor, M; Huang, T; Kissinger, CB; Kissinger, PT; Long, H; Zhu, Y | 1 |
| Ahmad, A; Farhan Asad, S; Hadi, SM; Singh, S | 1 |
| Buczyński, A; Krajewski, T; Magnuszewska, A; Olas, B; Wachowicz, B; Zbikowska, HM | 1 |
| Cabrini, L; Franconi, F; Juliano, C; Piu, L; Tadolini, B | 1 |
| Gowri, MS; Mietus-Snyder, M; Pitas, RE | 1 |
| Aggarwal, BB; Manna, SK; Mukhopadhyay, A | 1 |
| Iinuma, M; Ito, T; Nakaya, K; Riswan, S; Tanaka, T | 1 |
| Bremner, TA; Maheshwari, JG; Sacco, J; Tsan, MF; White, JE | 1 |
| Brundin, P; Burkitt, MJ; Emgard, M; Karlsson, J | 1 |
| Bakogeorgou, E; Castanas, E; Damianaki, A; Gemetzi, C; Hatzoglou, A; Kampa, M; Kouroumalis, E; Martin, PM; Notas, G; Panagiotou, S | 1 |
| Fujimoto, Y; Ikeda, N; Miura, T; Muraoka, S; Watanabe, M | 1 |
| Moreno, JJ | 1 |
| Chowrimootoo, G; Debnam, ES; Hahn, U; Kuhnle, G; Rice-Evans, C; Schroeter, H; Spencer, JP; Srai, SK | 1 |
| Andlauer, W; Fürst, P; Kolb, J; Siebert, K | 1 |
| Ikeda, K; Mizutani, K; Yamori, Y | 1 |
| Chu, Q; Gu, X; O'Dwyer, M; Zeece, M | 1 |
| Baldwin, AS; Holmes-McNary, M | 1 |
| Caderni, G; Davit, A; Sarotto, I; Tessitore, L | 1 |
| Aiello, FB; Brunetti, M; Caltagirone, S; Natali, PG; Piantelli, M; Poggi, A; Ranelletti, FO; Rossi, C | 1 |
| Ido, Y; Iinuma, M; Ito, T; Nakaya, KI; Riswan, S; Tanaka, T | 1 |
| De Santi, C; Mosca, F; Pacifici, GM; Pietrabissa, A; Spisni, R | 2 |
| Mahady, GB; Pendland, SL | 1 |
| Király-Véghely, Z; Szende, B; Tyihák, E | 1 |
| Barenghi, L; Beemster, P; Bertelli, AA; Bradamante, S; De Jong, JW; De Jonge, R; Piccinini, F | 2 |
| Badolo, L; Bergmann, C; Duranton, B; Gossé, F; Raul, F; Schneider, Y; Seiler, N; Vincent, F | 1 |
| Chen, JK; Huang, SS; Hung, LM; Lee, RS; Su, MJ | 1 |
| Fukuma, K; Kagami, J; Sankawa, U; Suh, DY | 1 |
| Nielsen, M; Ruch, RJ; Vang, O | 1 |
| Carcía-Parrilla, MC; Martínez-Ortega, MV; Troncoso, AM | 1 |
| Deitch, JA; Kirk, RI; Lerea, KM; Wu, JM | 1 |
| Christman, KL; O'Brian, CA; Stewart, JR | 1 |
| Bowers, JL; Jernigan, SC; Klinge, CM; Tyulmenkov, VV | 1 |
| Olas, B; Zbikowska, HM | 1 |
| Casper, RF; Fritz, PC; Ganss, B; Girard, B; Savouret, JF; Singh, SU; Sukhu, B; Tenenbaum, HC | 1 |
| Gil, JV; González-Candelas, L; Lamuela-Raventós, RM; Ramón, D | 1 |
| Chan, MM; Fong, D; Hwang, HS; Mattiacci, JA; Shah, A | 1 |
| Bastianetto, S; Quirion, R; Zheng, WH | 1 |
| Burkitt, MJ; Duncan, J | 1 |
| Baderschneider, B; Winterhalter, P | 1 |
| Ausserlechner, MJ; Bernhard, D; Csordas, A; Greil, R; Hübl, H; Kofler, R; Tinhofer, I; Tonko, M | 1 |
| Cantos, E; de Pascual-Teresa, S; García-Viguera, C; Tomás-Barberán, FA | 1 |
| Fischer, H; Illek, B; Kurth, MJ; Lee, V; Lizarzaburu, ME; Nantz, MH | 1 |
| Huber, J | 1 |
| Kimura, Y; Okuda, H | 2 |
| Chang, TK; Ko, HH; Lee, WB | 1 |
| Hsieh, SJ; Huang, HM; Jeng, KC; Kuo, JS; Wang, MJ | 1 |
| Doyle, PJ; Naderali, EK; Smith, SL; Williams, G | 1 |
| Davis, C; Heredia, A; Redfield, R | 1 |
| Chan, WK; Delucchi, AB | 1 |
| Ikeda, K; Mizutani, K; Nishikata, T; Yamori, Y | 1 |
| Alberto, P; Cerinic, MM; Falcini, F; Fernanda, F; Gabriele, S; Generini, S; Marco, MC; Pignone, A; Sergio, G; Simonini, G | 1 |
| Docherty, JJ; Fu, MM; Tsai, M | 1 |
| Baek, WK; Choi, YJ; Jang, MA; Jin, IN; Jun, DY; Kwon, TK; Lee, YS; Park, JW; Suh, MH; Suh, SI | 1 |
| Andrés-Lacueva, C; de La Torre-Boronat, MC; Lamuela-Raventós, RM; Romero-Pérez, AI | 1 |
| Bruder, JL; Hsieh, T; Lerea, KM; Olson, SC; Wu, JM | 1 |
| Cao, K; Hsieh, TC; Huang, Y; Len, J; Wu, JM; Yang, G; Yin, H; Zou, J | 1 |
| de Santi, C; Mosca, F; Pacifici, GM; Pietrabissa, A | 1 |
| Bartosíková, L; Karesová, P; Karpísek, M; Kollár, P; Kotolová, H; Necas, J | 1 |
| García-Foncillas, J; Jimenez, E; Perez, A; Redondo, P | 1 |
| Chen, L; Han, Y; Yang, F; Zhang, T | 1 |
| Freyberger, A; Hartmann, E; Hildebrand, H; Krötlinger, F | 1 |
| Ahmad, N; Katiyar, SK; Mukhtar, H | 1 |
| Benhamou, D; Bouaziz, H; Casper, RF; Fletcher, D; Gentilli, M; Mazoit, JX; Savouret, JF | 1 |
| Abou-Agag, LH; Aikens, ML; Benza, RL; Booyse, FM; Grenett, HE; Shows, SR; Tabengwa, EM | 1 |
| Bertelli, A; Bertelli, AA; Das, DK; Filippi, C; Giovannini, L; Longoni, BM; Migliori, M; Panichi, V | 1 |
| Bode, AM; Chen, NY; Dong, Z; Ma, WY; She, QB | 1 |
| Martínez-Tomé, M; Murcia, MA | 1 |
| Boyan, BD; Cochran, DL; Dean, DD; Liu, Y; Lohmann, CH; Schwartz, Z; Sisk, M; Sylvia, VL | 1 |
| Fowler, CJ; Hedin, HL; Jonsson, KO | 1 |
| Davis, FB; Davis, PJ; Lin, HY; Shih, A | 2 |
| Cheeke, P; Oleszek, W; Piacente, S; Pizza, C; Sitek, M; Stochmal, A | 1 |
| Park, JB | 1 |
| Bertelli, AA; Miloso, M; Nicolini, G; Rigolio, R; Tredici, G | 1 |
| Haugen, A; Mollerup, S; Ovrebø, S | 1 |
| Tou, J; Urbizo, C | 1 |
| Chang, TK; Yeung, RK | 1 |
| Chen, JK; Hung, LM; Lee, RS; Liang, HC; Su, MJ | 1 |
| Kitson, KE; Kitson, TM; Moore, SA | 1 |
| De Waard, MA; Del Sorbo, G; Schoonbeek, H | 1 |
| de la Torre-Boronat, MC; Ibern-Gómez, M; Lamuela-Raventós, RM; Roig-Pérez, S | 1 |
| Gilly, R; Mara, D; Oded, S; Zohar, K | 1 |
| Hioki, K; Kiyozuka, Y; Nakagawa, H; Senzaki, H; Shikata, N; Tsubura, A; Uemura, Y | 1 |
| Albini, A; Bianchi, L; Carafoli, F; Forti, L; Maga, G; Pagnoni, UM; Perucca, P; Prosperi, E; Savio, M; Stivala, LA; Vannini, V | 1 |
| Bielański, W; Bonior, J; Jachimczak, B; Jaworek, J; Konturek, PC; Konturek, SJ; Kot, M; Pawlik, WW; Sendur, R; Stachura, J; Tomaszewska, R | 1 |
| Adhami, VM; Afaq, F; Ahmad, N; Feyes, DK; Mukhtar, H | 1 |
| Olas, B; Wachowicz, B | 4 |
| Kaca, W; Olas, B; Saluk-Juszczak, J; Szewczuk, J; Wachowicz, B | 1 |
| Kozuki, Y; Miura, Y; Yagasaki, K | 1 |
| Brzozowski, T; Drozdowicz, D; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Ptak, A; Sliwowski, Z | 1 |
| Bertelli, AA; Ferrero, E; Ferrero, ME; Fulgenzi, A; Magni, E | 1 |
| Arous, N; Bachir, D; Galacteros, F; Garel, MC; Rodrigue, CM; Romeo, PH; Smith-Ravin, J | 1 |
| Bailey, SM; Cunningham, CC; Fialova, L; Fukui, Y; Ingelman-Sundberg, M; Janebova, M; Malbohan, I; Matsumoto, H; Mikulikova, L; Minowa, Y; Nespor, K; Neve, E; Nishitani, Y; Patel, VB; Popov, P; Sun, AY; Sun, GY; Zima, T | 1 |
| Goldberg, DM; Soleas, GJ; Yan, J | 3 |
| Angelini, M; Diamandis, EP; Goldberg, DM; Grass, L; Soleas, GJ | 1 |
| Burkhardt, S; Cabrera, J; Hardeland, R; Karbownik, M; Reiter, RJ; Tan, DX | 1 |
| Dörrie, J; Gerauer, H; Wachter, Y; Zunino, SJ | 1 |
| Barroso, CG; Domínguez, C; Guillén, DA | 1 |
| Hebbar, V; Kim, DW; Kong, AN; Mandlekar, S; Pezzuto, JM; Yu, R | 1 |
| Bedin, C; Bioulac-Sage, P; De Lédinghen, V; Desmoulière, A; Krisa, S; Monvoisin, A; Neaud, V; Payrastre, B; Rosenbaum, J | 1 |
| Bruder, JL; Hsieh, TC; Huang, YZ; Wang, ZR; Wu, JM; Zou, JG | 1 |
| Chelladurai, V; Ido, Y; Iinuma, M; Ito, T; Nakaya, K; Tanaka, T | 1 |
| Brede, O; Sprinz, H; Stojanović, S | 1 |
| Fukuhara, K; Furuta, A; Matsuoka, A; Miyata, N; Ozaki, M | 1 |
| Mahyar-Roemer, M; Roemer, K | 2 |
| Pervaiz, S | 3 |
| Anether, G; Bernhard, D; Csordas, A; Greil, R; Kofler, R; Kroemer, G; Loeffler, M; Senfter, M; Tinhofer, I | 1 |
| Miura, Y; Nihei, T; Yagasaki, K | 1 |
| Abe, I; Morita, H; Noguchi, H; Schröder, J | 1 |
| Bonomelli, A; Boulay, M; Breda, C; Buffard, D; Coutos-Thévenot, P; Esnault, R; Hain, R; Poinssot, B; Yean, H | 1 |
| Ito, Y; Yang, F; Zhang, T | 1 |
| Boyan, BD; Dean, DD; Del Toro, F; Hardin, RR; Schwartz, Z; Sylvia, VL | 1 |
| Holian, O; Walter, RJ | 1 |
| Atassi, G; Gusman, J; Malonne, H | 1 |
| Dannenberg, AJ; Subbaramaiah, K | 1 |
| Bråkenhielm, E; Cao, R; Cao, Y | 1 |
| Akoglu, B; Clausnitzer, A; Stein, J; Wolter, F | 1 |
| Igura, K; Kaji, K; Kuroda, Y; Ohta, T | 1 |
| Huang, KS; Lin, M; Wang, YH | 1 |
| Buczyński, A; Kaca, W; Olas, B; Saluk-Juszczak, J; Wachowicz, B; Zieliński, T | 1 |
| Bhat, KP; Pezzuto, JM | 2 |
| Chih, CL; Huang, SS; Hung, LM; Tsai, MC; Tsai, SK | 1 |
| Chen, YH; Lin, CH | 1 |
| Diamandis, EP; Goldberg, DM; Grass, L; Levesque, M; Soleas, GJ | 1 |
| Ardito, R; Boninsegna, A; Cittadini, A; Faraglia, B; Sgambato, A; Wolf, FI | 1 |
| Jang, JH; Surh, YJ | 2 |
| Cheng, GF; Huang, KS; Lin, M | 1 |
| Aumont, V; Battaglia, E; Krisa, S; Magdalou, J; Mérillon, JM; Netter, P; Richard, T; Sabolovic, N | 1 |
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| Fukumura, S; Hatakeyama, K; Hinotsu, S; Horio, Y; Ito, YM; Kawamura, K; Kawasaki, Y; Kozuka, N; Kuno, A; Mori, M; Nikaido, K; Seino, T; Tachi, N; Takami, A; Tsutsumi, H | 1 |
| Chin, D; de Pascual-Teresa, S; Günther, I; Kühn, G; Pallauf, K; Rimbach, G | 1 |
| Hamada, H; Horio, Y; Hosoda, R; Iwahara, N; Kuno, A; Nojima, I; Uesugi, D | 1 |
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| Kelleni, MT | 1 |
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| Apperloo, L; Bouma, EM; Dinesh Kumar, N; Moser, J; Nawijn, MC; Rodenhuis-Zybert, IA; Smit, JM; Ter Ellen, BM; Troost, B; van de Pol, DPI; van den Berge, M; van der Ende-Metselaar, HH; van der Voort, PHJ; van Gosliga, D | 1 |
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| Kmieć, Z; Siedlecka-Kroplewska, K; Wrońska, A | 1 |
| Chen, Y; Ji, S; Jia, P; Li, Y; Wang, T; Zhang, H | 1 |
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| Fujikawa, Y; Hiramatsu, K; Kamimori, M; Ohta, D; Okazawa, A; Onoda, Y; Tanimoto, H; Tsurumoto, T | 1 |
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| Gong, H; Huang, X; Li, L; Lu, F; Wang, R; Yuan, W; Zhang, L | 1 |
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| Fang, JY; Hung, CF; Lin, MH; Sung, HC; Yang, SC; Yu, HP | 1 |
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| Hamblin, MR; Homayounfal, M; Jafari, A; Loghman, A; Mirzaei, H; Roshani, M; Sheida, AH; Taghavi, T; Tamehri Zadeh, SS | 1 |
| Aguiar, GPS; Lima-Rezende, CA; Müller, LG; Oliveira, JV; Pedroso, J; Piato, A; Schneider, SE; Siebel, AM | 1 |
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| Börzsei, D; Deim, Z; Juhász, B; Lesi, ZN; Pálszabó, A; Pálszabó, P; Pósa, A; Priksz, D; Sebestyén, J; Szabó, R; Szász, A; Turcsán, Z; Varga, C; Veszelka, M | 1 |
| Alajarín, M; Beltrán, D; Berná, J; Espín, JC; Iglesias-Aguirre, CE; Puigcerver, J; Selma, MV; Vallejo, F | 1 |
| Chauhan, N; Koli, M; Nayak, SK; Singh, D; Subramanian, M | 1 |
| Ahmad, Z; Akhtar, MF; Akter, R; Al-Shaeri, M; Ashraf, GM; Karthika, C; Khan, FS; Klepacka, J; Mondal, B; Najda, A; Rahman, MH; Ramproshad, S; Saleem, A; Tagde, P; Zehravi, M | 1 |
| Bryl, A; Falkowski, M; Mrugacz, M; Zorena, K | 1 |
| Czajkowski, M; Józkowiak, M; Nowicki, A; Pawlak, M; Piotrowska-Kempisty, H; Rolle, K; Skupin-Mrugalska, P; Wawrzyniak, D; Wierzchowski, M | 1 |
| Duprey, D; Durand, P; Ghrairi, T; Ghzaiel, I; Ksila, M; Latruffe, N; Lizard, G; Masmoudi-Kouki, O; Meziane, S; Nury, T; Prost, M; Prost-Camus, E; Vejux, A; Vervandier-Fasseur, D | 1 |
| Asemi, Z; Dana, PM; Davoodvandi, A; Sharif, PM | 1 |
| Aguilar-Aguilar, E; Alajarín, M; Beltrán, D; Berná, J; Espín, JC; Iglesias-Aguirre, CE; Puigcerver, J; Selma, MV; Vallejo, F | 1 |
| Cao, YH; Fu, D; Huang, ZY; Jiang, GX; Li, CG; Li, S; Li, W; Liu, JB; Ma, YS; Shen, B; Xin, R; Zhang, J; Zou, DZ | 1 |
| Chen, X; Jia, R; Li, L; Song, X; Wang, Y; Yin, Z; Zhang, Y; Zhao, X; Zou, Y | 1 |
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| Begum, MY; Chidambaram, K; Fuloria, NK; Fuloria, S; Gan, SH; Jeyabalan, S; Khattulanuar, FS; Kumarasamy, V; Lum, PT; Maziz, MNH; Nordin, R; Rani, NNIM; Ravi, S; Safi, SZ; Sathasivam, KV; Sekar, M; Subramaniyan, V; Wu, YS | 1 |
| Bohara, RA; Gigli, G; Leporatti, S; Ragusa, A; Singh, MP; Tabassum, N | 1 |
| Li, X; Liu, X; Wang, J; Wang, S; Yin, J; Zhang, B; Zhang, X; Zhang, Y; Zhao, C | 1 |
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| Li, X; Liu, X; Wang, J; Wang, S; Xing, X; Yin, J; Zhang, B; Zhang, X; Zhang, Y | 1 |
| Arroo, R; Barut, B; Kuruüzüm-Uz, A; Özel, A; Sari, S; Şöhretoğlu, D | 1 |
| Cai, X; Kong, Q; Li, X; Ren, X; Zeng, Q | 1 |
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| Adachi, Y; Nakajima, M; Nemoto, T; Yamauchi, T | 1 |
| Behroozaghdam, M; Bishayee, A; De Greef, D; Dehghani, M; Hasani Sadi, F; Hashemi, M; Javanshir, S; Kamali, D; Mirzaei, S; Rashidi, M; Tabari, T; Zabolian, A; Zarepour, A; Zarrabi, A | 1 |
| Ganesan, K; Mohandas, S; Nagarajan, S; Ramkumar, KM; Xu, B | 1 |
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| Cielecka-Piontek, J; Miklaszewski, A; Paczkowska-Walendowska, M | 1 |
| Duan, W; Fan, P; Jiang, J; Li, S; Li, Y; Liang, Z; Mu, H; Wang, L; Wei, Y; Yuan, L | 1 |
| Amaral, MH; Krambeck, K; Santos, D; Sousa Lobo, JM | 1 |
| Kobylka, P; Kucinska, M; Kujawski, J; Lazewski, D; Murias, M; Wierzchowski, M | 1 |
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| Crowe-White, KM; DiNatale, JC | 1 |
| Chen, S; Fan, D; Huang, K; Li, Z; Liu, C; Wang, T; Zhang, Z | 1 |
| Bai, Z; Chen, L; Deng, L; Geng, H; Wang, G; Xia, C; Yao, J | 1 |
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828 review(s) available for resveratrol and stilbenes
| Article | Year |
|---|---|
Resveratrol: a molecule whose time has come? And gone?
Topics: Acyltransferases; Chromatography; Fruit; Fungi; Humans; Lipid Metabolism; Male; Mitosporic Fungi; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 1997 |
Selected phenolic compounds in cultivated plants: ecologic functions, health implications, and modulation by pesticides.
Topics: Animals; Coronary Disease; Coumarins; Ecology; Flavonoids; Herbicides; Humans; Phenols; Plants; Resveratrol; Stilbenes | 1999 |
Resveratrol, map kinases and neuronal cells: might wine be a neuroprotectant?
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Ethanol; Humans; In Vitro Techniques; Learning; Memory; Neuroblastoma; Neurons; Oxidative Stress; Phosphorylation; Rats; Resveratrol; Stilbenes | 1999 |
Nonalcoholic compounds of wine: the phytoestrogen resveratrol and moderate red wine consumption during menopause.
Topics: Clinical Trials as Topic; Estrogens, Non-Steroidal; Ethanol; Female; Humans; Isoflavones; Menopause; Phytoestrogens; Plant Preparations; Resveratrol; Stilbenes; Wine | 1999 |
Cardioprotection of red wine: role of polyphenolic antioxidants.
Topics: Antioxidants; Coronary Disease; Flavonoids; Humans; Phenols; Plant Extracts; Platelet Aggregation Inhibitors; Polymers; Polyphenols; Reperfusion Injury; Resveratrol; Stilbenes; Wine | 1999 |
Chemoprevention of cancer and cardiovascular disease by resveratrol.
Topics: Anticarcinogenic Agents; Carcinogens; Cardiovascular Diseases; Cell Cycle; Cyclin D1; Enzyme Inhibitors; Gene Expression Regulation; Growth Substances; Humans; Lipid Peroxidation; Neoplasms; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; Receptor Protein-Tyrosine Kinases; Resveratrol; Risk Factors; Rosales; Signal Transduction; Stilbenes; Transcription, Genetic; Wine | 1999 |
Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances.
Topics: Animals; Capsaicin; Catechin; Catechols; Curcumin; Diet; Fatty Alcohols; Humans; Mice; Neoplasms; Neoplasms, Experimental; Phenols; Plants, Edible; Plants, Medicinal; Resveratrol; Stilbenes | 1999 |
Biological effects of resveratrol.
Topics: Anticarcinogenic Agents; Antioxidants; Arteriosclerosis; Humans; Resveratrol; Rosales; Stilbenes; Wine | 2000 |
Analysis of resveratrol in wine by capillary electrophoresis.
Topics: Electrophoresis, Capillary; Resveratrol; Stilbenes; Wine | 2000 |
[Phytoestrogens and SERMS, alternatives to classical hormone therapy?].
Topics: Aged; Anticarcinogenic Agents; Breast Neoplasms; Estrogen Replacement Therapy; Estrogens, Non-Steroidal; Female; Genistein; Humans; Isoflavones; Middle Aged; Osteoporosis, Postmenopausal; Phytoestrogens; Plant Preparations; Postmenopause; Receptors, Estrogen; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes | 2000 |
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Endothelium, Vascular; Humans; In Vitro Techniques; Melatonin; Nitric Oxide; Oxidative Stress; Pregnatrienes; Probucol; Raynaud Disease; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Scleroderma, Systemic; Selenium; Stilbenes; Vitamin E | 2000 |
Antioxidants in chemoprevention of skin cancer.
Topics: Administration, Oral; Administration, Topical; Allyl Compounds; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Curcumin; Female; Flavonoids; Humans; Male; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Papilloma; Phenols; Phytotherapy; Plants, Medicinal; Polymers; Reactive Oxygen Species; Resveratrol; Silymarin; Skin Neoplasms; Stilbenes; Sulfides; Tea; Ultraviolet Rays; Zingiber officinale | 2001 |
[Biological activity of resveratrol].
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cardiovascular Diseases; Humans; Inflammation; Neoplasms; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2001 |
Ethanol and oxidative stress.
Topics: Alcoholism; Animals; Antioxidants; Central Nervous System Depressants; Cytochrome P-450 CYP2E1; Ethanol; Flavonoids; Humans; Liver; Liver Diseases, Alcoholic; Mice; NF-kappa B; Oxidative Stress; Phenols; Polymers; Polyphenols; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2001 |
Mechanism of cardioprotection by resveratrol, a phenolic antioxidant present in red wine (Review).
Topics: Animals; Antioxidants; Coronary Disease; Humans; Resveratrol; Stilbenes; Wine | 2001 |
Resveratrol--from the bottle to the bedside?
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Neoplasms; Resveratrol; Stilbenes | 2001 |
A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Transformation, Neoplastic; Humans; Neoplasms; Resveratrol; Stilbenes | 2001 |
The world of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Arteriosclerosis; Biological Availability; Cell Division; Gene Transfer, Horizontal; Humans; Inflammation; Intestinal Absorption; Neoplasms; Resveratrol; Stilbenes; Vitis | 2001 |
The effects of resveratrol on CYP1A1 expression and aryl hydrocarbon receptor function in vitro.
Topics: Anticarcinogenic Agents; Cytochrome P-450 CYP1A1; Humans; Neoplasms; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Biological effects of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Binding Sites; Estrogens; Heart; Humans; Light; Models, Biological; Models, Chemical; Receptors, Estrogen; Resveratrol; Stilbenes; Vasodilator Agents | 2001 |
The "French Paradox" and beyond: neuroprotective effects of polyphenols.
Topics: Antioxidants; Coronary Disease; Flavonoids; France; Free Radicals; Humans; Neurodegenerative Diseases; Neurons; Oxidative Stress; Phenols; Polymers; Polyphenols; Resveratrol; Stilbenes; Vitis | 2002 |
Botanical antioxidants for chemoprevention of photocarcinogenesis.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Apigenin; Curcumin; Flavonoids; Humans; Radiation-Protective Agents; Resveratrol; Silymarin; Skin Neoplasms; Stilbenes; Tea; Ultraviolet Rays | 2002 |
Signal transduction pathways: targets for chemoprevention of skin cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cell Transformation, Neoplastic; Disease Models, Animal; Humans; Isothiocyanates; NF-kappa B; Phytic Acid; Resveratrol; Signal Transduction; Skin Neoplasms; Stilbenes; Tea; Transcription Factor AP-1 | 2000 |
Phytoalexins from the Vitaceae: biosynthesis, phytoalexin gene expression in transgenic plants, antifungal activity, and metabolism.
Topics: Acyltransferases; Fungi; Fungicides, Industrial; Gene Expression; Phytoalexins; Plant Diseases; Plant Extracts; Plants; Plants, Genetically Modified; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Vitaceae | 2002 |
Resveratrol and cancer: a review.
Topics: Antineoplastic Agents, Phytogenic; Estrogens; Humans; Neoplasms; Polygonum; Receptors, Estrogen; Resveratrol; Stilbenes; Xenobiotics | 2002 |
Cancer chemopreventive activity of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Humans; Neoplasms; Resveratrol; Stilbenes | 2002 |
Molecular targets for nutrients involved with cancer prevention.
Topics: Anticarcinogenic Agents; Calcium; Diet; Folic Acid; Food Technology; Genistein; Humans; Neoplasms; Nutritional Physiological Phenomena; Polymorphism, Genetic; Resveratrol; Selenium; Stilbenes; Vitamin D | 2001 |
Anti-leukemia effect of resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Hematopoietic Stem Cells; Humans; Leukemia; Resveratrol; Stilbenes | 2002 |
Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer.
Topics: Antioxidants; Cardiovascular Diseases; Carotenoids; Chronic Disease; Dietary Fiber; Estrogens, Non-Steroidal; Food; Humans; Isoflavones; Isothiocyanates; Lycopene; Monoterpenes; Neoplasms; Olive Oil; Phenols; Phytoestrogens; Phytosterols; Plant Oils; Plant Preparations; Resveratrol; Stilbenes; Tea | 2002 |
Structural concepts in cancer prevention.
Topics: Anticarcinogenic Agents; Chemoprevention; Clinical Trials as Topic; Female; Humans; Male; Mass Screening; Neoplasms; Prognosis; Resveratrol; Risk Assessment; Sensitivity and Specificity; Stilbenes; Structure-Activity Relationship | 2002 |
The basis for the chemopreventive action of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cardiovascular Diseases; Humans; Neoplasms; Resveratrol; Stilbenes | 2002 |
Resveratrol and cancer: chemoprevention, apoptosis, and chemo-immunosensitizing activities.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Humans; Neoplasms; Resveratrol; Stilbenes | 2003 |
Cancer chemoprevention by resveratrol: in vitro and in vivo studies and the underlying mechanisms (review).
Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Diet; Humans; In Vitro Techniques; Models, Chemical; Neoplasms; Resveratrol; Stilbenes | 2003 |
Pharmacological studies on resveratrol.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arachidonic Acid; Cell Degranulation; Chemical and Drug Induced Liver Injury; Glucosides; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Neoplasm Metastasis; Neutrophils; Phytotherapy; Polygonum; Resveratrol; Stilbenes | 2003 |
The study of phenolic compounds as natural antioxidants in wine.
Topics: Antioxidants; Flavonoids; Free Radicals; Gallic Acid; Phenols; Polymers; Quercetin; Resveratrol; Rutin; Solutions; Spain; Spectrophotometry; Stilbenes; Wine | 2003 |
Resveratrol: a candidate nutritional substance for prostate cancer prevention.
Topics: Antineoplastic Agents, Phytogenic; Diet; ErbB Receptors; Flavonoids; Humans; Male; Phenols; Polymers; Polyphenols; Prostatic Neoplasms; Resveratrol; Stilbenes | 2003 |
From sandwiches to center stage. Peanuts pack a powerful nutritional punch.
Topics: Arachis; Coronary Disease; Fatty Acids, Monounsaturated; Health Promotion; Humans; Menu Planning; Neoplasms; Phytosterols; Resveratrol; Stilbenes; Stroke | 2003 |
The aryl hydrocarbon receptor and its xenobiotic ligands: a fundamental trigger for cardiovascular diseases.
Topics: Cardiovascular Diseases; Humans; Ligands; Nicotiana; Receptors, Aryl Hydrocarbon; Resveratrol; Smoking; Stilbenes; Xenobiotics | 2003 |
Pleiotropic effects of resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Coronary Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Isoenzymes; Neoplasms; Pain; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes | 2003 |
Wine and resveratrol: mechanisms of cancer prevention?
Topics: Alcohol Drinking; Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Chemoprevention; Humans; Mortality; Neoplasms; Resveratrol; Risk Factors; Stilbenes; Wine | 2003 |
Relationship between mechanisms, bioavailibility, and preclinical chemopreventive efficacy of resveratrol: a conundrum.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Biological Availability; Humans; Neoplasms; Palliative Care; Phenols; Resveratrol; Ribonucleotide Reductases; Rodentia; Stilbenes; Vasodilator Agents | 2003 |
Resveratrol: from grapevines to mammalian biology.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Cardiotonic Agents; Gene Expression; Mammals; Neuroprotective Agents; Resveratrol; Stilbenes; Transcription Factors; Wine | 2003 |
[Progress in cardiovascular protective effects of resveratrol].
Topics: Animals; Antioxidants; Arteriosclerosis; Cardiovascular Agents; Humans; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Vasodilator Agents | 2003 |
[Biological effects of resveratrol and other constituents of wine].
Topics: Animals; Antioxidants; Humans; Resveratrol; Stilbenes; Wine | 2003 |
Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism.
Topics: Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Humans; Intestinal Absorption; Mass Spectrometry; Resveratrol; Stilbenes | 2003 |
Redifferentiation therapy for thyroid cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Transformation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phenylacetates; Phenylbutyrates; Receptors, Cytoplasmic and Nuclear; Resveratrol; Retinoids; Stilbenes; Thyroid Neoplasms; Transcription Factors | 2004 |
Pitfalls of animal model systems in ageing research.
Topics: Aging; Animals; Biomarkers; Dehydroepiandrosterone; Humans; Models, Animal; Research; Resveratrol; Selegiline; Stilbenes | 2004 |
Transport of resveratrol, a cancer chemopreventive agent, to cellular targets: plasmatic protein binding and cell uptake.
Topics: Animals; Anticarcinogenic Agents; Biological Transport; Blood Proteins; Fatty Acids; Humans; Protein Binding; Resveratrol; Serum Albumin; Stilbenes; Tumor Cells, Cultured | 2004 |
Mechanisms of cardiovascular protection by resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Cardiovascular Agents; Cardiovascular Diseases; Cell Division; Humans; Phytoestrogens; Resveratrol; Signal Transduction; Stilbenes | 2004 |
Molecular basis of chemoprevention by resveratrol: NF-kappaB and AP-1 as potential targets.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Chemoprevention; Humans; Neoplasms; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor AP-1 | 2004 |
Cardiovascular protective effects of resveratrol.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Cholesterol; Dose-Response Relationship, Drug; Humans; Lipid Peroxidation; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Time Factors | 2004 |
Flavonoids and resveratrol as regulators of Ah-receptor activity: protection from dioxin toxicity.
Topics: Animals; Dioxins; Environmental Pollution; Flavonoids; Food Contamination; Gene Expression Regulation, Enzymologic; Humans; Molecular Structure; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2003 |
New progression in the study of protective properties of resveratrol in anticardiovascular disease.
Topics: Animals; Cardiovascular Diseases; Humans; Protective Agents; Resveratrol; Stilbenes | 2004 |
Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines?
Topics: Animals; Anticarcinogenic Agents; Colorectal Neoplasms; Humans; Phytotherapy; Polyamines; Resveratrol; Stilbenes; Vitis; Wine | 2004 |
[Pharmacological capacities of the prevention of colorectal cancer].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Calcium; Colorectal Neoplasms; Dietary Fiber; Feeding Behavior; Folic Acid; Humans; Resveratrol; Stilbenes | 2004 |
Resveratrol regulates cellular PKC alpha and delta to inhibit growth and induce apoptosis in gastric cancer cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Enzyme Activation; Fas Ligand Protein; Humans; Membrane Glycoproteins; Nitric Oxide Synthase; Protein Kinase C; Resveratrol; Stilbenes; Stomach Neoplasms | 2005 |
Metabolism and bioavailability of trans-resveratrol.
Topics: Absorption; Animals; Biological Availability; Diet; Humans; Intestinal Absorption; Organ Specificity; Rats; Resveratrol; Stilbenes; Wine | 2005 |
Resveratrol and breast cancer chemoprevention: molecular mechanisms.
Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Humans; Phosphatidylinositol 3-Kinases; Phytoestrogens; Resveratrol; Signal Transduction; Stilbenes; Xenobiotics | 2005 |
Chemotherapeutic potential of the chemopreventive phytoalexin resveratrol.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biological Availability; Cell Line, Tumor; Humans; Neoplasms; Phytoalexins; Plant Extracts; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2004 |
Nutraceuticals as anti-angiogenic agents: hopes and reality.
Topics: Angiogenesis Inhibitors; Animals; Atherosclerosis; Catechin; Curcumin; Dietary Supplements; Flavonoids; Humans; Neoplasms; Neovascularization, Pathologic; Phenols; Polyphenols; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2005 |
Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Division; Humans; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasms, Experimental; Neovascularization, Pathologic; Resveratrol; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2005 |
Resveratrol: preventing properties against vascular alterations and ageing.
Topics: Aging; Arteriosclerosis; Cardiovascular Diseases; Foam Cells; Health Promotion; Humans; Lipoproteins; Macrophages; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Oxidative Stress; Platelet Aggregation; Resveratrol; Stilbenes; Vasodilation | 2005 |
Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications.
Topics: Aging; Anti-Inflammatory Agents; Biological Availability; Fruit; Humans; Longevity; Macrophages; Mast Cells; Monocytes; Neutrophils; Plants; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Transcription Factors; Wine | 2005 |
Toward a unified theory of caloric restriction and longevity regulation.
Topics: Aging; Animals; Caloric Restriction; Cell Survival; Cytokines; Gene Expression Regulation; Glucocorticoids; Histone Deacetylases; Humans; Immunity, Innate; Longevity; Models, Biological; Models, Chemical; Niacinamide; Nicotinamide Phosphoribosyltransferase; Reactive Oxygen Species; Resveratrol; Saccharomyces cerevisiae; Sirtuins; Stilbenes | 2005 |
Genotoxicity of phytoestrogens.
Topics: Animals; Anthocyanins; Cell Proliferation; Flavonoids; Genistein; Genomic Instability; Humans; Isoflavones; Lignans; Mutagens; Phytoestrogens; Resveratrol; Stilbenes; Zearalenone | 2005 |
Resveratrol: a medical drug for acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pancreatitis; Resveratrol; Stilbenes | 2005 |
A forkhead in the road to longevity: the molecular basis of lifespan becomes clearer.
Topics: Aging; Animals; Evolution, Molecular; Flavonoids; Gene Expression Profiling; Humans; Niacinamide; Oligonucleotide Array Sequence Analysis; Phenols; Polyphenols; Reactive Oxygen Species; Receptor, Insulin; Receptors, Somatomedin; Resveratrol; RNA Interference; Sirtuins; Stilbenes; Transcription Factors | 2005 |
Unique properties of polyphenol stilbenes in the brain: more than direct antioxidant actions; gene/protein regulatory activity.
Topics: Animals; Antioxidants; Cerebrovascular Disorders; Encephalitis; Flavonoids; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Humans; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Phenols; Polyphenols; Resveratrol; Stilbenes | 2005 |
Dietary antioxidant compounds and liver health.
Topics: alpha-Tocopherol; Animals; Antioxidants; beta Carotene; Biological Availability; Carotenoids; Diet; Flavonoids; Health Promotion; Humans; Liver; Liver Diseases; Lycopene; Phenols; Polyphenols; Quercetin; Resveratrol; Stilbenes; Vitamin A | 2004 |
Modulation of signal transduction by tea catechins and related phytochemicals.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Capsaicin; Catechin; Curcumin; Genistein; Humans; Molecular Structure; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Tea; Transcription Factors | 2005 |
[Possible candidates for the compound which is expected to attenuate dioxin toxicity].
Topics: Animals; Anti-Ulcer Agents; Curcumin; Cytochrome P-450 CYP1A1; Diterpenes; Food Contamination; Humans; Mice; Mice, Inbred C57BL; Oryza; Plant Oils; Poisoning; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2005 |
Regulation of gene transcription by botanicals: novel regulatory mechanisms.
Topics: Animals; Bridged Bicyclo Compounds; Catechin; Gene Expression Regulation; Glycine max; Humans; Isoflavones; Peroxisome Proliferator-Activated Receptors; Phloroglucinol; Plants; Pregnane X Receptor; Proteasome Endopeptidase Complex; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Resveratrol; Sirtuins; Stilbenes; Terpenes; Transcription, Genetic; Ubiquitin | 2005 |
Resveratrol, a phenolic antioxidant with effects on blood platelet functions.
Topics: Animals; Antioxidants; Blood Platelets; Humans; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2005 |
Resveratrol as an anticancer nutrient: molecular basis, open questions and promises.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Cycle Proteins; Cell Death; Diet; Humans; Nitric Oxide Synthase; Phenols; Phytoestrogens; Prostaglandin-Endoperoxide Synthases; Resveratrol; Signal Transduction; Sphingolipids; Stilbenes | 2005 |
Antioxidants and myocardial ischemia: reperfusion injuries.
Topics: Animals; Antioxidants; Calcium; Endothelium, Vascular; Humans; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Reactive Oxygen Species; Resveratrol; Stilbenes | 2005 |
Structure-activity relationship of trans-resveratrol and its analogues.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Drug Design; Humans; Lipid Peroxidation; Resveratrol; Ribonucleotide Reductases; Stilbenes; Structure-Activity Relationship; Wine | 2005 |
Cancer biology and hormesis: comments on Calabrese (2005).
Topics: Adaptation, Physiological; Antineoplastic Agents; Carcinogens; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; No-Observed-Adverse-Effect Level; Resveratrol; Risk Assessment; Stilbenes; Suramin; Tamoxifen; Tumor Cells, Cultured | 2005 |
Comparative studies of the antioxidant effects of cis- and trans-resveratrol.
Topics: Animals; Antioxidants; Inflammation; Interferon-gamma; Kluyveromyces; Lipid Peroxidation; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Rats; Reactive Oxygen Species; Resveratrol; Stereoisomerism; Stilbenes | 2006 |
Resveratrol in cardioprotection: a therapeutic promise of alternative medicine.
Topics: Antioxidants; Cardiotonic Agents; Complementary Therapies; Humans; Ischemic Preconditioning; Reactive Oxygen Species; Resveratrol; Stilbenes | 2006 |
Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Cycle; Humans; Neoplasms; Radiation-Sensitizing Agents; Resveratrol; Stilbenes | 2006 |
Vascular dysfunction in aging: potential effects of resveratrol, an anti-inflammatory phytoestrogen.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes; Vasodilator Agents | 2006 |
Therapeutic potential of resveratrol: the in vivo evidence.
Topics: Aging; Animals; Heart Diseases; Humans; Inflammation; Myocardial Infarction; Neoplasms; Protective Agents; Resveratrol; Stilbenes; Stroke | 2006 |
Resveratrol--a boon for treating Alzheimer's disease?
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Brain; Caloric Restriction; Humans; Nerve Degeneration; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
[Resveratrol--evaluation of anticancer activity].
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Evaluation Studies as Topic; Humans; Neoplasm Transplantation; Neoplasms; Plant Extracts; Resveratrol; Stilbenes; Wine | 2006 |
The roles of polyphenols in cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; Cell Communication; Cyclooxygenase Inhibitors; Diet; Flavonoids; Gap Junctions; Genistein; Humans; Matrix Metalloproteinases; Neoplasms; Oxidative Stress; Phenols; Polyphenols; Prostaglandin-Endoperoxide Synthases; Quercetin; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Resveratrol modulation of signal transduction in apoptosis and cell survival: a mini-review.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Humans; Inhibitor of Apoptosis Proteins; MAP Kinase Signaling System; Microtubule-Associated Proteins; Mitochondria; Models, Biological; Neoplasm Proteins; Neoplasms; NF-kappa B; Protein-Tyrosine Kinases; Resveratrol; Signal Transduction; Stilbenes; Survivin | 2006 |
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.
Topics: Aging; Animals; Anticonvulsants; Antioxidants; Blueberry Plants; Caenorhabditis elegans; Ethosuximide; Ethylenediamines; Ginkgo biloba; Longevity; Organometallic Compounds; Plant Extracts; Resveratrol; Salicylates; Stilbenes; Tocotrienols; Trimethadione; Ubiquinone; Vitamin E | 2006 |
Botanical antioxidants in the prevention of photocarcinogenesis and photoaging.
Topics: Antioxidants; Genistein; Humans; Lythraceae; Plant Extracts; Resveratrol; Skin; Skin Aging; Skin Neoplasms; Stilbenes; Tea | 2006 |
Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets.
Topics: Alzheimer Disease; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blueberry Plants; Clinical Trials as Topic; Cognition; Curcumin; Flavonoids; Ginkgo biloba; Humans; Neurodegenerative Diseases; Parkinson Disease; Phenols; Plant Extracts; Polyphenols; Proteasome Endopeptidase Complex; Resveratrol; Signal Transduction; Stilbenes; Tea; Wine | 2006 |
Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kappaB and AP-1 as prime targets.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Mice; NF-kappa B; Resveratrol; Signal Transduction; Skin; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2006 |
Genistein and resveratrol: mammary cancer chemoprevention and mechanisms of action in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Administration, Oral; Adolescent; Age Factors; Animals; Antioxidants; Carcinogens; Cell Differentiation; Chemoprevention; Diet; Drug Administration Schedule; Drug Synergism; Estradiol; Female; Gene Expression Regulation; Genistein; Humans; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Molecular Structure; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Sexual Maturation; Soy Foods; Stilbenes; Wine | 2006 |
The proteasome as a potential target for novel anticancer drugs and chemosensitizers.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Catechin; Clinical Trials as Topic; Curcumin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Genistein; Humans; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Structure-Activity Relationship; Ubiquitin | 2006 |
SIR2: a potential target for calorie restriction mimetics.
Topics: Aging; Animals; Caenorhabditis elegans; Caloric Restriction; Enzyme Inhibitors; Humans; Longevity; Metabolic Syndrome; Models, Biological; Nerve Degeneration; Resveratrol; Saccharomyces cerevisiae; Sirtuins; Stilbenes | 2007 |
Small molecule inhibitors of Stat3 signaling pathway.
Topics: Animals; Antineoplastic Agents; Curcumin; Flavonoids; Humans; Piperidines; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Triterpenes | 2007 |
Resveratrol: a review of preclinical studies for human cancer prevention.
Topics: Animals; Anticarcinogenic Agents; Drug Screening Assays, Antitumor; Humans; Neoplasms; Resveratrol; Stilbenes | 2007 |
Resveratrol in cell fate decisions.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Electron Transport; Energy Metabolism; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
An anti-aging drug today: from senescence-promoting genes to anti-aging pill.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Cell Cycle Proteins; Cellular Senescence; Drug Delivery Systems; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Longevity; Metformin; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Saccharomyces cerevisiae Proteins; Sirolimus; Sirtuins; Stilbenes | 2007 |
Diet and cancer risk in Mediterranean countries: open issues.
Topics: Breast Neoplasms; Case-Control Studies; Diet, Mediterranean; Digestive System Neoplasms; Flavonoids; Humans; Italy; Mediterranean Region; Micronutrients; Resveratrol; Risk Factors; Stilbenes | 2006 |
Inhibitors of stress-activated protein/mitogen-activated protein kinase pathways.
Topics: 4-Butyrolactone; Animals; Flavones; Humans; Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes | 2007 |
Natural products as a gold mine for arthritis treatment.
Topics: Animals; Arthritis; Curcumin; Ergosterol; Humans; Phytotherapy; Plant Preparations; Pregnenediones; Resveratrol; Stilbenes; Triterpenes; Withania | 2007 |
[The influence of isoflavonoids on the antitumor activity of vitamin D3].
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Cholecalciferol; Colonic Neoplasms; Female; Humans; Isoflavones; Male; Mice; Prostatic Neoplasms; Receptors, Calcitriol; Resveratrol; Steroid Hydroxylases; Stilbenes; Tumor Cells, Cultured; Up-Regulation; Vitamin D3 24-Hydroxylase | 2007 |
Wine, research and cardiovascular disease: instructions for use.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Dose-Response Relationship, Drug; Humans; Plant Extracts; Rats; Research Design; Resveratrol; Stilbenes; Wine | 2007 |
The red wine hypothesis: from concepts to protective signalling molecules.
Topics: Alcohol Drinking; Animals; Arteriosclerosis; Coronary Disease; Female; Flavonoids; Humans; Hypertension; Male; Mice; Phenols; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyphenols; Rats; Resveratrol; Risk Factors; Stilbenes; Wine | 2007 |
Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential.
Topics: Cardiovascular Diseases; Cell Cycle; Chemoprevention; Chemotherapy, Adjuvant; Diabetes Mellitus; Gene Expression Regulation; Humans; Inflammation; Neoplasms; Neovascularization, Pathologic; Resveratrol; Signal Transduction; Stilbenes | 2007 |
Effect of non-alcoholic compounds of alcoholic drinks on the pancreas.
Topics: Alcoholic Beverages; Animals; Camellia sinensis; Disease Models, Animal; Ellagic Acid; Ethanol; Humans; Pancreas; Pancreatitis, Alcoholic; Plant Extracts; Quercetin; Rats; Resveratrol; Stilbenes | 2007 |
Homo obesus: a metabotrophin-deficient species. Pharmacology and nutrition insight.
Topics: Brain-Derived Neurotrophic Factor; Caloric Restriction; Energy Metabolism; Glucose; Humans; Lipid Metabolism; Nerve Growth Factor; Nutritional Physiological Phenomena; Obesity; Resveratrol; Stilbenes | 2007 |
Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Catechin; Curcumin; Humans; Indoles; Neoplasms; Resveratrol; Stilbenes | 2007 |
Resveratrol: from basic science to the clinic.
Topics: Animals; Biomedical Research; Cellular Senescence; Humans; NF-kappa B; Phytoalexins; Plants; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2007 |
Anti-inflammatory responses of resveratrol.
Topics: Anti-Inflammatory Agents; Cardiotonic Agents; Free Radicals; Humans; Inflammation; Inflammation Mediators; Models, Biological; Resveratrol; Stilbenes; Transcription Factors | 2007 |
Drug interactions involving ethanol and alcoholic beverages.
Topics: Alcoholic Beverages; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Humans; Pharmaceutical Preparations; Resveratrol; Stilbenes; Wine | 2007 |
[SIRT1/PGC-1: a neuroprotective axis?].
Topics: Acetylation; Amyloid beta-Peptides; Animals; Cells, Cultured; Humans; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Protein Processing, Post-Translational; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factors; Transcriptional Activation | 2007 |
Resveratrol as an antioxidant and pro-oxidant agent: mechanisms and clinical implications.
Topics: Antioxidants; Cell Transformation, Neoplastic; Humans; Nitrogen; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
Beneficial drugs for liver diseases.
Topics: Adrenal Cortex Hormones; Animals; Colchicine; Curcumin; Disease Models, Animal; Drug Combinations; Glycyrrhizic Acid; Humans; Interferons; Liver Diseases; Nitric Oxide; Plant Extracts; Resveratrol; S-Adenosylmethionine; Silymarin; Stilbenes; Thalidomide | 2008 |
Cell cycle control as a basis for cancer chemoprevention through dietary agents.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Cycle; Cell Proliferation; Curcumin; Cyclin-Dependent Kinases; Diet; Genistein; Humans; Neoplasms; Resveratrol; Silymarin; Stilbenes; Tea | 2008 |
AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.
Topics: Acetylation; Enzyme Activation; Enzyme Activators; Humans; Nuclear Proteins; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factors; Tumor Suppressor Protein p53 | 2007 |
Natural antioxidants in Alzheimer's disease.
Topics: Acetylcarnitine; Alzheimer Disease; Animals; Antioxidants; Cholinesterase Inhibitors; Humans; Neuroprotective Agents; Oxidative Stress; Resveratrol; Stilbenes | 2007 |
New enlightenment of French Paradox: resveratrol's potential for cancer chemoprevention and anti-cancer therapy.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cardiovascular Diseases; Cell Line, Tumor; Cell Transformation, Neoplastic; Clinical Trials as Topic; Diet; Europe; France; Gene Expression Regulation, Neoplastic; Humans; Incidence; Mice; Mice, Inbred A; Neoplasms; Resveratrol; Stilbenes; Wine | 2007 |
Cancer chemoprevention through dietary antioxidants: progress and promise.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Carotenoids; Curcumin; Dietary Supplements; Fruit; Genistein; Humans; Lycopene; Neoplasms; Oxidative Stress; Pentacyclic Triterpenes; Resveratrol; Stilbenes; Triterpenes | 2008 |
Potential for metabolic engineering of resveratrol biosynthesis.
Topics: Animals; Animals, Genetically Modified; Dietary Supplements; Forecasting; Genetic Enhancement; Plants, Genetically Modified; Resveratrol; Stilbenes | 2008 |
Sirt1 protects the heart from aging and stress.
Topics: Aging; Animals; Apoptosis; Caloric Restriction; Heart; Heart Diseases; Heart Failure; Humans; Longevity; Mice; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Resveratrol; Saccharomyces cerevisiae; Sirtuin 1; Sirtuins; Stilbenes; Up-Regulation | 2008 |
Resveratrol: a therapeutic promise for cardiovascular diseases.
Topics: Antioxidants; Cardiovascular Diseases; Flavonoids; Models, Biological; Molecular Structure; Phenols; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes; Wine | 2007 |
Modulation of sirtuins: new targets for antiageing.
Topics: Aging; Animals; Dementia; Enzyme Inhibitors; Humans; Models, Biological; Reactive Oxygen Species; Resveratrol; Sirtuins; Stilbenes | 2008 |
Effects of dietary polyphenols on gene expression in human vascular endothelial cells.
Topics: Cardiovascular Diseases; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Humans; Nitric Oxide Synthase; Oligonucleotide Array Sequence Analysis; Phenols; Polyphenols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Umbilical Veins | 2008 |
Targeting the mitochondria to augment myocardial protection.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Drug Delivery Systems; Homeostasis; Humans; Ischemic Preconditioning; Mitochondria; Multienzyme Complexes; Myocardial Reperfusion Injury; Nitrites; Organophosphorus Compounds; Protein Serine-Threonine Kinases; Resveratrol; Stilbenes; Ubiquinone | 2008 |
Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation.
Topics: Aging; Alzheimer Disease; Animals; Antioxidants; Heart Diseases; Humans; Resveratrol; Sirtuins; Skin Aging; Stilbenes; Wine | 2008 |
Sirtuins: novel targets for metabolic disease.
Topics: Base Sequence; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Enzyme Inhibitors; Humans; Metabolic Diseases; Molecular Sequence Data; Molecular Structure; Obesity; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2008 |
Resveratrol: a multitargeted agent for age-associated chronic diseases.
Topics: Aging; Cardiotonic Agents; Gene Expression Regulation; Gene Regulatory Networks; Inflammation; Intracellular Signaling Peptides and Proteins; Neoplasms; Platelet Aggregation; Resveratrol; Stilbenes; Transcription Factors | 2008 |
Resveratrol: one molecule, many targets.
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2008 |
Wine, spirits and the lung: good, bad or indifferent?
Topics: Adenocarcinoma; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Altitude Sickness; Antioxidants; Asthma; Female; Humans; Lung; Lung Neoplasms; Male; Pulmonary Disease, Chronic Obstructive; Pulmonary Edema; Respiratory Distress Syndrome; Resveratrol; Stilbenes; Sulfites; Wine | 2006 |
Resveratrol and ischemic preconditioning in the brain.
Topics: Animals; Brain Ischemia; Humans; Ischemic Preconditioning; Neuroprotective Agents; Resveratrol; Signal Transduction; Stilbenes; Synapses | 2008 |
Moderate wine consumption in the prevention of metabolic syndrome and its related medical complications.
Topics: Alcohol Drinking; Animals; Antioxidants; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Metabolic Syndrome; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Wine | 2008 |
Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Apoptosis; Carcinogens; Cell Survival; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; NF-kappa B; Protein Kinase C; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Sirtuins: novel targets for metabolic disease in drug development.
Topics: Animals; Antioxidants; Caloric Restriction; Diabetes Mellitus; Drug Design; Enzyme Activation; Humans; Insulin; Male; Mice; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Substrate Specificity | 2008 |
Molecular mechanism of apoptosis induction by resveratrol, a natural cancer chemopreventive agent.
Topics: Anticarcinogenic Agents; Apoptosis; Biological Products; Chemoprevention; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Pharmacometrics of stilbenes: seguing towards the clinic.
Topics: Humans; Resveratrol; Stilbenes | 2006 |
Potential of resveratrol in anticancer and anti-inflammatory therapy.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Arachis; Biological Availability; Cyclooxygenase Inhibitors; Fruit; Humans; Phytotherapy; Resveratrol; Stilbenes; Vitis; Wine | 2008 |
Dietary polyphenols mediated regulation of oxidative stress and chromatin remodeling in inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Chromatin Assembly and Disassembly; Curcumin; Diet; Flavonoids; Inflammation; Oxidative Stress; Phenols; Polyphenols; Resveratrol; Stilbenes | 2008 |
Resveratrol: a natural compound with pharmacological potential in neurodegenerative diseases.
Topics: Animals; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Pain; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2008 |
Resveratrol in prevention and treatment of common clinical conditions of aging.
Topics: Aged; Aging; Animals; Antioxidants; Humans; Mice; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2008 |
Trans-resveratrol: a magical elixir of eternal youth?
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Humans; Molecular Structure; Resveratrol; Sirtuins; Stilbenes | 2008 |
Resveratrol and novel potent activators of SIRT1: effects on aging and age-related diseases.
Topics: Aging; Animals; Biological Availability; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Enzyme Activation; Enzyme Activators; Humans; Inflammation; Neurodegenerative Diseases; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2008 |
Opposite effects of metabolic syndrome and calorie restriction on thrombotic disease: heads and tails of the same coin--resveratrol's role.
Topics: Animals; Blood Coagulation; Caloric Restriction; Fibrinolytic Agents; Humans; Metabolic Syndrome; Myocardial Ischemia; Resveratrol; Sirtuins; Stilbenes; Thrombosis; Ventricular Function, Left; Wine | 2009 |
Red wine and cardiovascular risks.
Topics: Alcohol Drinking; Animals; Aorta; Atherosclerosis; Cardiovascular Diseases; Color; Endothelium, Vascular; Flavonoids; Humans; Models, Animal; Phenols; Polyphenols; Resveratrol; Risk Assessment; Stilbenes; Thrombosis; Vascular Diseases; Vasodilator Agents; Wine | 2006 |
Bioactivity and structure of biophenols as mediators of chronic diseases.
Topics: Animals; Antioxidants; Biological Availability; Chronic Disease; Diet; Flavonoids; Health Promotion; Humans; Phenols; Plants, Edible; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Phytoceuticals: mighty but ignored weapons against Helicobacter pylori infection.
Topics: Flavonoids; Garlic; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Panax; Phytotherapy; Plant Preparations; Resveratrol; Stilbenes; Tea | 2008 |
Molecular engineering of resveratrol in plants.
Topics: Acyltransferases; Enhancer Elements, Genetic; Epigenesis, Genetic; Plant Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Resveratrol; Stilbenes; Transgenes | 2009 |
Alcohol in moderation, cardioprotection, and neuroprotection: epidemiological considerations and mechanistic studies.
Topics: Alcohol Drinking; Animals; Antioxidants; Cardiotonic Agents; Cardiovascular Diseases; Central Nervous System Depressants; Dementia; Ethanol; Humans; Neuroprotective Agents; Nitric Oxide; Protein Kinase C; Resveratrol; Stilbenes | 2009 |
Cancer chemoprevention and mitochondria: targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state.
Topics: Animals; Apoptosis; Capsaicin; Catechin; Chemoprevention; Disease Models, Animal; Humans; Mitochondrial Membranes; Neoplasms; Permeability; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea | 2009 |
Beneficial effects of resveratrol on atherosclerosis.
Topics: Antioxidants; Atherosclerosis; Cholesterol, LDL; Humans; Inflammation; Oxidative Stress; Phytotherapy; Platelet Aggregation; Reactive Oxygen Species; Resveratrol; Stilbenes; Vasodilator Agents; Vitis | 2008 |
Resveratrol addiction: to die or not to die.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Cardiotonic Agents; Cell Cycle; Cell Death; Cell Division; Cell Survival; Fruit; Humans; Receptors, Estrogen; Resveratrol; Stilbenes; Substance-Related Disorders | 2009 |
Phytochemicals as potential chemopreventive and chemotherapeutic agents in hepatocarcinogenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brassicaceae; Caffeine; Capsaicin; Carcinoma, Hepatocellular; Catechin; Chemoprevention; Curcumin; Flavonoids; Humans; Liver Neoplasms; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2009 |
Cardioprotective actions of grape polyphenols.
Topics: Antioxidants; Cardiovascular Diseases; Flavonoids; Fruit; Humans; Inflammation; Oxidative Stress; Phenols; Phytotherapy; Plant Preparations; Platelet Aggregation; Polyphenols; Resveratrol; Seeds; Stilbenes; Vasodilation; Vitis; Wine | 2008 |
Therapeutic potential of resveratrol in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Dementia; Flavonoids; Humans; Nerve Degeneration; Phenols; Polyphenols; Resveratrol; Stilbenes; Wine | 2008 |
The potential role of natural agents in treatment of airway inflammation.
Topics: Ambroxol; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Cystic Fibrosis; Diet; Expectorants; Humans; Justicia; Lung Diseases, Obstructive; Phytotherapy; Picrorhiza; Pneumonia; Prostaglandins; Resveratrol; Stilbenes; Treatment Outcome; Tylophora | 2007 |
Comparative neuroprotective properties of stilbene and catechin analogs: action via a plasma membrane receptor site?
Topics: Amyloid beta-Peptides; Autoradiography; Catechin; Cell Membrane; Flavonoids; Neuroprotective Agents; Phenols; Polyphenols; Prealbumin; Protein Kinase C-delta; Resveratrol; Stilbenes; Structure-Activity Relationship; Tea | 2009 |
Cellular effects of resveratrol in skeletal muscle.
Topics: Animals; Antioxidants; Diet; Humans; Muscle, Skeletal; Oxidative Stress; Proteins; Resveratrol; Stilbenes | 2009 |
[Advances in resveratrol studies].
Topics: Genetic Engineering; Plants; Resveratrol; Stilbenes | 2008 |
Resveratrol and chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cardiovascular Diseases; Drug Evaluation, Preclinical; Gene Expression Regulation; Humans; Neoplasms; Neoplasms, Hormone-Dependent; Phytoestrogens; Resveratrol; Signal Transduction; Stilbenes | 2009 |
Cellular signaling perturbation by natural products.
Topics: Antineoplastic Agents; Carotenoids; Catechin; Curcumin; Humans; Indoles; Isoflavones; Lycopene; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2009 |
Resveratrol and neurodegenerative diseases: activation of SIRT1 as the potential pathway towards neuroprotection.
Topics: Animals; Humans; Models, Biological; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Signal Transduction; Sirtuins; Stilbenes | 2009 |
Chemoprevention with phytochemicals targeting inducible nitric oxide synthase.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Benzyl Alcohols; Catechin; Chemoprevention; Coumarins; Curcumin; Flavones; Mice; Nitric Oxide Synthase Type II; Rats; Resveratrol; Sesquiterpenes; Stilbenes | 2009 |
Resveratrol: a promising agent in promoting cardioprotection against coronary heart disease.
Topics: Animals; Coronary Disease; Diabetes Mellitus; Endothelial Cells; Glucose; Glucose Transporter Type 4; Heart; Humans; Hypercholesterolemia; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2009 |
PGC-1alpha in aging and anti-aging interventions.
Topics: Aging; Animals; Antioxidants; Heat-Shock Proteins; Humans; Mitochondria; Models, Biological; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Processing, Post-Translational; Resveratrol; Stilbenes; Transcription Factors | 2009 |
Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Humans; Neoplasms; Resveratrol; Stilbenes | 2009 |
Resveratrol: its biologic targets and functional activity.
Topics: Angiogenesis Inhibitors; Animals; Humans; Models, Biological; Oxidative Stress; Resveratrol; Signal Transduction; Stilbenes | 2009 |
The pro-apoptotic action of stilbene-induced COX-2 in cancer cells: convergence with the anti-apoptotic effect of thyroid hormone.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cyclooxygenase 2; Cytokines; Enzyme Inhibitors; Humans; Neoplasms; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Thyroid Hormones | 2009 |
Sirtuin activators.
Topics: Animals; Biological Availability; Drug Delivery Systems; Drug Design; Enzyme Activators; Flavonoids; Humans; Obesity; Phenols; Polyphenols; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Wine, resveratrol and health: a review.
Topics: Anticoagulants; Antineoplastic Agents, Phytogenic; Biological Availability; Cardiovascular Agents; Diet, Mediterranean; Humans; Lipid Metabolism; Neoplasms; Protective Agents; Resveratrol; Stilbenes; Vitis; Wine | 2009 |
Metabolic benefits from Sirt1 and Sirt1 activators.
Topics: AMP-Activated Protein Kinases; Animals; Caloric Restriction; Diabetes Mellitus, Type 2; Diet; Disease Models, Animal; Energy Metabolism; Humans; Mice; Mice, Transgenic; NAD; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription, Genetic | 2009 |
Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cathepsins; Cell Cycle; Cell Division; Female; Humans; Inflammation; Leukemia; Lymphoma; Male; Neoplasms; Prostatic Neoplasms; Resveratrol; Safety; Stilbenes; Transcription Factors | 2009 |
Impact of aging on the angiogenic potential of the myocardium: implications for angiogenic therapies with emphasis on sirtuin agonists.
Topics: Aging; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Collateral Circulation; Coronary Vessels; Humans; Myocardial Ischemia; Resveratrol; Sirtuins; Stilbenes | 2009 |
The biological responses to resveratrol and other polyphenols from alcoholic beverages.
Topics: Alcoholic Beverages; Animals; Antioxidants; Flavonoids; Health; Humans; Intestinal Absorption; Phenols; Polyphenols; Resveratrol; Stilbenes | 2009 |
Resveratrol: cellular actions of a potent natural chemical that confers a diversity of health benefits.
Topics: Biological Products; Health; Humans; Resveratrol; Stilbenes | 2009 |
Could Sirt1-mediated epigenetic effects contribute to the longevity response to dietary restriction and be mimicked by other dietary interventions?
Topics: Aging; Animals; Antioxidants; Diet, Reducing; DNA; DNA Methylation; Epigenomics; Feeding Behavior; Gene Expression Regulation, Developmental; Humans; Longevity; Resveratrol; Ribonucleotide Reductases; Sirtuin 1; Stilbenes | 2009 |
Resveratrol: biologic and therapeutic implications.
Topics: Animals; Blood Glucose; Caloric Restriction; Cardiovascular Agents; Cardiovascular Diseases; Dietary Carbohydrates; Dietary Fats; Energy Intake; Homeostasis; Humans; Lipid Metabolism; Metabolic Syndrome; Molecular Structure; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Biological and medicinal properties of grapes and their bioactive constituents: an update.
Topics: Antioxidants; Fruit; Humans; Molecular Structure; Phytotherapy; Plant Extracts; Protective Agents; Resveratrol; Stilbenes; Vitis | 2009 |
Resveratrol: a natural polyphenol with multiple chemopreventive properties.
Topics: Antioxidants; Molecular Structure; Resveratrol; Stilbenes | 2009 |
Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Ligands; Mammals; Mitochondria; Models, Molecular; Protein Conformation; Resveratrol; Sirtuins; Stilbenes; Substrate Specificity; Suramin; Tissue Distribution | 2010 |
Grapes, wines, resveratrol, and heart health.
Topics: Cardiotonic Agents; Heart Diseases; Humans; Longevity; Resveratrol; Stilbenes; Vitis; Wine | 2009 |
Is the use of resveratrol in the treatment and prevention of obesity premature?
Topics: Adult; Animals; Antioxidants; Child; Drug Administration Schedule; Humans; Inflammation; Intra-Abdominal Fat; Kidney; Obesity; Phenols; Plant Extracts; Resveratrol; Stilbenes | 2009 |
NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets.
Topics: Animals; Epigenesis, Genetic; HIV Infections; Humans; Inhibitory Concentration 50; Models, Chemical; NAD; Neoplasms; Niacinamide; Protein Binding; Resveratrol; Signal Transduction; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Stilbenes | 2010 |
Bioproduction of resveratrol and stilbene derivatives by plant cells and microorganisms.
Topics: Bacteria; Biotechnology; Cell Culture Techniques; Humans; Organisms, Genetically Modified; Plants; Resveratrol; Stilbenes; Yeasts | 2009 |
Biochemical effects of SIRT1 activators.
Topics: Animals; Cardiotonic Agents; Energy Metabolism; Enzyme Activation; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin Resistance; Learning; Longevity; Memory; Mice; Models, Biological; NAD; Neoplasms; Niacinamide; O-Acetyl-ADP-Ribose; Resveratrol; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Stilbenes | 2010 |
Curcumin, resveratrol and flavonoids as anti-inflammatory, cyto- and DNA-protective dietary compounds.
Topics: Animals; Anti-Inflammatory Agents; Curcumin; Cytoprotection; DNA Damage; Flavonoids; Humans; Resveratrol; Stilbenes | 2010 |
Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Resveratrol; Stilbenes | 2010 |
Apoptosis by dietary agents for prevention and treatment of prostate cancer.
Topics: Adenocarcinoma; Aged; Animals; Apoptosis; Carotenoids; Catechin; Clinical Trials as Topic; Curcumin; Drug Screening Assays, Antitumor; Flavonoids; Flavonols; Genistein; Humans; Lycopene; Lythraceae; Male; Mice; Mice, Nude; Mice, Transgenic; Middle Aged; Neoplasm Proteins; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2010 |
Cellular mechanisms of cardioprotection by calorie restriction: state of the science and future perspectives.
Topics: Aged; Animals; Antioxidants; Apoptosis; Autophagy; Caloric Restriction; Cardiovascular Diseases; Disease Models, Animal; Forecasting; Heart Diseases; Homeostasis; Humans; Inflammation; Inflammation Mediators; Mitochondria, Heart; Mitochondrial Diseases; Obesity; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes | 2009 |
The role of Sirt1: at the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Caloric Restriction; Humans; Longevity; NAD; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Sirtuins regulate key aspects of lipid metabolism.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Caloric Restriction; Dietary Fats; Enzyme Activation; Humans; Insulin; Insulin Secretion; Lipid Metabolism; Liver; Mice; Models, Biological; Muscle, Skeletal; Obesity; Resveratrol; Sirtuins; Stilbenes | 2010 |
The potential of resveratrol against human gliomas.
Topics: Antineoplastic Agents; Brain Neoplasms; Glioma; Humans; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2010 |
Resveratrol bioavailability and toxicity in humans.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biological Availability; Biotransformation; Humans; Phytotherapy; Resveratrol; Stilbenes; Toxicity Tests | 2010 |
Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; DNA Adducts; Estrogens; Female; Humans; Male; Neoplasms; Resveratrol; Stilbenes | 2010 |
Metabolic effects of resveratrol in mammals--a link between improved insulin action and aging.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Humans; Insulin; Insulin-Secreting Cells; Longevity; Mammals; Mice; Obesity; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Emerging role of resveratrol in the treatment of severe acute pancreatitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytokines; Humans; Interleukin-1; Interleukin-6; NF-kappa B; Pancreatitis, Acute Necrotizing; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Naturally occurring phytochemicals for the prevention of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Cognition Disorders; Curcumin; Dietary Supplements; Humans; Oxidative Stress; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2010 |
[Contemporary view of plant antioxidants role in prevention of civilization diseases].
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Chronic Disease; Dietary Supplements; Flavonoids; Health Promotion; Humans; Neoplasms; Phenols; Phytotherapy; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2009 |
Antiviral activity of resveratrol.
Topics: Antioxidants; Antiviral Agents; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53; Virus Diseases; Virus Replication; Viruses | 2010 |
Resveratrol mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for chemoprevention of cancer.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Chemoprevention; Copper; DNA Damage; Humans; Lymphocytes; Neoplasms; Resveratrol; Stilbenes | 2010 |
Validation of anti-aging drugs by treating age-related diseases.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Antioxidants; Biomarkers; Chronic Disease; Humans; Hypoglycemic Agents; Metformin; Resveratrol; Sirolimus; Stilbenes; Validation Studies as Topic | 2009 |
Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Autophagy; Caenorhabditis elegans; Drosophila; Histone Acetyltransferases; Humans; I-kappa B Kinase; Longevity; Resveratrol; Saccharomyces cerevisiae; Sirtuin 1; Spermidine; Stilbenes | 2009 |
Antiangogenic effect of selected phytochemicals.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Curcumin; Humans; Plants; Resveratrol; Stilbenes | 2010 |
Antioxidant and anti-inflammatory effects of resveratrol in airway disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Humans; Inflammation; Lung Diseases, Obstructive; Oxidative Stress; Resveratrol; Stilbenes | 2010 |
Resveratrol, sirtuins, and the promise of a DR mimetic.
Topics: ADP Ribose Transferases; Animals; Diet; Diet, Reducing; Energy Metabolism; Humans; Longevity; Obesity; Primates; Resveratrol; Saccharomyces cerevisiae; Sirtuins; Stilbenes | 2010 |
Resveratrol and resveratrol analogues--structure-activity relationship.
Topics: Animals; Antineoplastic Agents; Free Radical Scavengers; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2010 |
Diabetes mellitus, inflammation, obesity: proposed treatment pathways for current and future therapies.
Topics: Adiponectin; Animals; Anti-Inflammatory Agents; Anti-Obesity Agents; Antioxidants; Diabetes Mellitus; Ghrelin; Humans; Hypoglycemic Agents; Inflammation; Leptin; Obesity; Resveratrol; Stilbenes | 2010 |
Resveratrol and red wine, healthy heart and longevity.
Topics: Aging; Anti-Inflammatory Agents; Antimutagenic Agents; Antioxidants; Cardiotonic Agents; Chemoprevention; Flavonoids; Heart; Humans; Longevity; Phenols; Platelet Aggregation Inhibitors; Polyphenols; Resveratrol; Stilbenes; Wine | 2010 |
Resveratrol, obesity and diabetes.
Topics: Animals; Diabetes Mellitus; Humans; Obesity; Resveratrol; Stilbenes | 2010 |
Resveratrol as a therapeutic agent for neurodegenerative diseases.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Antioxidants; Cell Death; Humans; Inflammation; Neurodegenerative Diseases; Neuroglia; Neurons; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Resveratrol; Stilbenes; Stroke | 2010 |
trans-Resveratrol as a neuroprotectant.
Topics: Animals; Biological Availability; Cell Line, Tumor; Cells, Cultured; Humans; Mice; Neuroprotective Agents; Rats; Resveratrol; Stilbenes; Superoxide Dismutase | 2010 |
Targeting resveratrol to mitochondria for cardiovascular diseases.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cardiovascular System; Drug Delivery Systems; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Patents as Topic; Resveratrol; Stilbenes | 2010 |
Anti-inflammatory activities of resveratrol in the brain: role of resveratrol in microglial activation.
Topics: Animals; Anti-Inflammatory Agents; Brain; Cell Line; Humans; Inflammation; Microglia; Resveratrol; Stilbenes | 2010 |
Cancer stem cells: a novel paradigm for cancer prevention and treatment.
Topics: AC133 Antigen; Antigens, CD; Breast Neoplasms; Colonic Neoplasms; Curcumin; Female; Glycoproteins; Hedgehog Proteins; Humans; Neoplastic Stem Cells; Pancreatic Neoplasms; Peptides; Protein Serine-Threonine Kinases; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Moderate red wine consumption and cardiovascular disease risk: beyond the "French paradox".
Topics: Alcohol Drinking; Antioxidants; Atherosclerosis; Blood Pressure; Cardiovascular Diseases; Cholesterol, HDL; Coronary Artery Disease; Endothelium, Vascular; Fibrinolysis; Hemostasis; Humans; Resveratrol; Stilbenes; Wine | 2010 |
An overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders.
Topics: Animals; Apoptosis; Drug Design; Drugs, Investigational; Humans; Melatonin; Mitochondria; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes | 2010 |
Fighting cancer with red wine? Molecular mechanisms of resveratrol.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Humans; Neoplasms; Resveratrol; Stilbenes; Wine | 2009 |
Targeting mitochondria for cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Membrane Permeability; HSP90 Heat-Shock Proteins; Humans; Indoles; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pyrroles; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Anti-atherogenic effects of resveratrol.
Topics: Animals; Antioxidants; Atherosclerosis; Cardiovascular Diseases; Humans; Lipids; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2010 |
Modulation of apoptosis by natural products for cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Clinical Trials as Topic; Gossypol; Humans; Mitochondria; Neoplasms; Pentacyclic Triterpenes; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Triterpenes; Vitamin E | 2010 |
The Cardiovascular Nutrapharmacology of Resveratrol: Pharmacokinetics, Molecular Mechanisms and Therapeutic Potential
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cardiovascular System; Humans; Resveratrol; Stilbenes | 2010 |
Calorie restriction: what recent results suggest for the future of ageing research.
Topics: Animals; Antimetabolites; Biomedical Research; Biomimetics; Caloric Restriction; Deoxyglucose; Enzyme Inhibitors; Hypoglycemic Agents; Longevity; Metformin; Primates; Quality of Life; Resveratrol; Sirolimus; Stilbenes | 2010 |
Mechanisms of vascular aging: new perspectives.
Topics: Aging; Animals; Apoptosis; Atherosclerosis; Blood Vessels; Caloric Restriction; Endothelium, Vascular; Exercise; Humans; Inflammation; Oxidative Stress; Resveratrol; Stem Cells; Stilbenes; Vascular Diseases | 2010 |
Beer and its non-alcoholic compounds: role in pancreatic exocrine secretion, alcoholic pancreatitis and pancreatic carcinoma.
Topics: Beer; Catechin; Ellagic Acid; Humans; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Pancreatitis, Alcoholic; Quercetin; Resveratrol; Stilbenes | 2010 |
[Chemopreventive and chemotherapeutic effect of trans-resveratrol and its analogues in cancer].
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Neoplasms; Resveratrol; Stilbenes | 2010 |
Resveratrol and derivatives for the prevention and treatment of cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Molecular Structure; Neoplasms; Resveratrol; Stilbenes | 2010 |
Regulatory role of resveratrol on Th17 in autoimmune disease.
Topics: Autoimmune Diseases; Humans; Immunosuppressive Agents; Resveratrol; Stilbenes; Th17 Cells | 2011 |
Ageing and neurodegenerative diseases.
Topics: Aging; Antioxidants; Humans; Longevity; Neurodegenerative Diseases; Resveratrol; Stilbenes | 2010 |
Resveratrol. Monograph.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Evidence-Based Medicine; Humans; Inflammation; Metabolic Syndrome; Neoplasms; Phytotherapy; Protective Agents; Resveratrol; Stilbenes | 2010 |
Complex I disorders: causes, mechanisms, and development of treatment strategies at the cellular level.
Topics: Antioxidants; Child; Child, Preschool; Developmental Disabilities; Disease Progression; Drug Delivery Systems; Electron Transport Complex I; Energy Metabolism; Humans; Infant; Infant, Newborn; Mitochondrial Diseases; Organophosphorus Compounds; Oxidative Phosphorylation; Plastoquinone; Resveratrol; Stilbenes; Ubiquinone | 2010 |
Resveratrol: a relevant pharmacological approach for the treatment of metabolic syndrome?
Topics: Adenylate Kinase; Caloric Restriction; Humans; Metabolic Syndrome; Phytotherapy; Plant Extracts; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
The potential influence of plant polyphenols on the aging process.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Curcumin; Flavonoids; Humans; Life Expectancy; Longevity; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Vasodilator Agents | 2010 |
Resveratrol and cardiovascular health.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Health Behavior; Humans; Lipoproteins, LDL; Resveratrol; Stilbenes | 2010 |
Dietary polyphenols: focus on resveratrol, a promising agent in the prevention of cardiovascular diseases and control of glucose homeostasis.
Topics: Animals; Anti-Inflammatory Agents; Cardiovascular Diseases; Cholesterol; Glucose; Homeostasis; Humans; Macrophages; Myocardial Reperfusion Injury; Platelet Aggregation; Resveratrol; Stilbenes | 2010 |
Sirtuin family: a link to metabolic signaling and senescence.
Topics: Aging; Anti-Inflammatory Agents, Non-Steroidal; Humans; NAD; Resveratrol; Signal Transduction; Sirtuins; Stilbenes | 2010 |
Resveratrol: a multifunctional cytoprotective molecule.
Topics: Antineoplastic Agents; Antioxidants; Cell Death; Cytoprotection; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ischemic Preconditioning, Myocardial; Oxidative Stress; Phytotherapy; Plant Preparations; Reperfusion Injury; Resveratrol; Stilbenes | 2010 |
Targeting metabolic syndrome: candidate natural agents.
Topics: Animals; Anthocyanins; Berberine; China; Curcumin; Female; Flavanones; Genistein; Ginsenosides; Humans; Male; Medicine, Traditional; Metabolic Syndrome; Mice; Momordica charantia; Phytotherapy; Plant Preparations; Prevalence; Randomized Controlled Trials as Topic; Rats; Resveratrol; Stilbenes | 2010 |
Colorectal cancer: chemopreventive role of curcumin and resveratrol.
Topics: Animals; Anticarcinogenic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Humans; Resveratrol; Stilbenes | 2010 |
Chemopreventive potential of natural compounds in head and neck cancer.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Curcumin; Cyclooxygenase 2 Inhibitors; ErbB Receptors; Head and Neck Neoplasms; Humans; NF-kappa B; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2010 |
Potential of the dietary antioxidants resveratrol and curcumin in prevention and treatment of hematologic malignancies.
Topics: Antioxidants; Apoptosis; Cell Cycle; Cell Proliferation; Clinical Trials as Topic; Curcumin; Diet; Hematologic Neoplasms; Humans; Molecular Structure; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Resveratrol: challenges in translation to the clinic--a critical discussion.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Dietary Supplements; Drug Delivery Systems; Evaluation Studies as Topic; Humans; Models, Biological; Resveratrol; Stilbenes; Translational Research, Biomedical | 2010 |
Dietary lipophilic antioxidants: implications and significance in the aging process.
Topics: Antioxidants; Cardiovascular Diseases; Diet; Dietary Supplements; Free Radicals; Humans; Life Style; Longevity; Oxidative Stress; Resveratrol; Stilbenes; Ubiquinone; Vitamin A; Vitamin E | 2010 |
Bioprocess and bioreactor: next generation technology for production of potential plant-based antidiabetic and antioxidant molecules.
Topics: Antioxidants; Arachis; Bioreactors; Biotechnology; Ginsenosides; Hypoglycemic Agents; Plant Roots; Resveratrol; Stilbenes; Triterpenes | 2011 |
Effects of resveratrol and other wine polyphenols on vascular function: an update.
Topics: Antioxidants; Atherosclerosis; Blood Platelets; Cell Adhesion Molecules; Endothelium, Vascular; Flavonoids; Humans; Nitric Oxide; Oxidative Stress; Phenols; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes; Wine | 2011 |
Resveratrol commonly displays hormesis: occurrence and biomedical significance.
Topics: Animals; Apoptosis; Biomedical Research; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endpoint Determination; Humans; Models, Biological; Resveratrol; Stilbenes | 2010 |
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1.
Topics: Aging; Biological Availability; Cardiovascular Diseases; Enzyme Activators; Humans; Learning; Longevity; Memory; Neoplasms; Nervous System Diseases; Obesity; Phenols; Resveratrol; Sirtuins; Stilbenes | 2010 |
A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 2.
Topics: Aging; Biological Availability; Cardiovascular Diseases; Enzyme Activators; Humans; Longevity; Neoplasms; Nervous System Diseases; Obesity; Phenols; Resveratrol; Sirtuins; Stilbenes | 2010 |
[Structures of oligostilbenoids in dipterocarpaceaeous plants and their biological activities].
Topics: Dipterocarpaceae; Drug Discovery; Drug Evaluation, Preclinical; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2011 |
The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges.
Topics: Animals; Antioxidants; Humans; Oxidative Stress; Resveratrol; Skin; Skin Diseases; Stilbenes; Vitis | 2011 |
Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning.
Topics: Animals; Antioxidants; Biotransformation; Brain Ischemia; Caloric Restriction; Cell Death; DNA Damage; Humans; Ischemic Preconditioning; Mitochondria; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2011 |
Resveratrol and cellular mechanisms of cancer prevention.
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Bioavailability of resveratrol.
Topics: Absorption; Animals; Biological Availability; Humans; Resveratrol; Stilbenes | 2011 |
Resveratrol: a cardioprotective substance.
Topics: Animals; Cardiotonic Agents; Coronary Disease; Humans; Resveratrol; Stilbenes; Wine | 2011 |
Resveratrol in cardiovascular health and disease.
Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Cardiovascular System; Cell Survival; Health Status; Humans; Longevity; Resveratrol; Stilbenes | 2011 |
Anti-diabetic effects of resveratrol.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Resveratrol; Stilbenes | 2011 |
Effect of resveratrol on fat mobilization.
Topics: Adipogenesis; Adipose Tissue; Animals; Humans; Lipolysis; Obesity; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Transport, stability, and biological activity of resveratrol.
Topics: Animals; Antioxidants; Biological Transport, Active; Cell Membrane; Humans; Membrane Transport Proteins; Resveratrol; Stilbenes | 2011 |
Chemoprevention in experimental animals.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemoprevention; Clinical Trials as Topic; Disease Models, Animal; Humans; Neoplasms; Resveratrol; Stilbenes | 2011 |
Resveratrol modulates astroglial functions: neuroprotective hypothesis.
Topics: Animals; Astrocytes; Glutamic Acid; Humans; Neuronal Plasticity; Neuroprotective Agents; Oxidative Stress; Resveratrol; Stilbenes | 2011 |
Resveratrol and apoptosis.
Topics: Animals; Apoptosis; Cyclooxygenase 2; Humans; Integrin alphaVbeta3; Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Chemopreventive effects of resveratrol and resveratrol derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Chemoprevention; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
The beneficial effect of resveratrol on severe acute pancreatitis.
Topics: Acute Disease; Animals; Humans; Oxidative Stress; Pancreatitis; Resveratrol; Severity of Illness Index; Stilbenes | 2011 |
Neuroprotective properties of resveratrol and derivatives.
Topics: Alzheimer Disease; Animals; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Stilbenes | 2011 |
MicroRNA signatures of resveratrol in the ischemic heart.
Topics: Animals; Humans; MicroRNAs; Myocardial Ischemia; Resveratrol; Stilbenes | 2011 |
Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2011 |
The phenomenon of resveratrol: redefining the virtues of promiscuity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cassia; Drug Delivery Systems; Humans; Neoplasms; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Safety of resveratrol with examples for high purity, trans-resveratrol, resVida(®).
Topics: Animals; Drug Contamination; Humans; Reproduction; Resveratrol; Stilbenes; Toxicity Tests | 2011 |
Resveratrol and life extension.
Topics: Aging; Animals; Caloric Restriction; Humans; Life Expectancy; Longevity; Resveratrol; Stilbenes | 2011 |
Resveratrol in cancer management: where are we and where we go from here?
Topics: Animals; Chemoprevention; Disease Management; Humans; Neoplasms; Resveratrol; Stilbenes | 2011 |
Chemosensitization of tumors by resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Resistance, Neoplasm; Fruit; Humans; Neoplasms; Resveratrol; Stilbenes; Vegetables | 2011 |
Clinical trials of resveratrol.
Topics: Animals; Clinical Trials as Topic; Humans; Resveratrol; Stilbenes | 2011 |
Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy.
Topics: Animals; Cardiomegaly; Cell Survival; Coronary Vessels; Enzyme Activators; Gene Expression; Heart Failure; Humans; Myocardium; Myocytes, Cardiac; Neovascularization, Physiologic; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2011 |
Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe.
Topics: Animals; Apoptosis; Autophagy; Humans; Mitosis; Phytotherapy; Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Targeting cell signaling and apoptotic pathways by dietary agents: role in the prevention and treatment of cancer.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Clinical Trials as Topic; Curcuma; Curcumin; Diet; Disease Models, Animal; Fruit; Genistein; Humans; Neoplasms; Resveratrol; Signal Transduction; Silymarin; Stilbenes; United States; Vegetables | 2011 |
Implications of cancer stem cell theory for cancer chemoprevention by natural dietary compounds.
Topics: Alkaloids; Animals; Anticarcinogenic Agents; Benzodioxoles; beta Catenin; Carotenoids; Catechin; Cell Differentiation; Cell Proliferation; Cholecalciferol; Curcumin; Diet; Humans; Isoflavones; Isothiocyanates; Lycopene; Neoplasms; Neoplastic Stem Cells; Piperidines; Polyunsaturated Alkamides; Resveratrol; Signal Transduction; Stilbenes; Sulfoxides; Thiocyanates; Wnt Proteins | 2011 |
After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders.
Topics: Alzheimer Disease; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Neurodegenerative Diseases; Parkinson Disease; Resveratrol; Sirtuins; Stilbenes; Up-Regulation | 2011 |
Inhibitors of microglial neurotoxicity: focus on natural products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzyl Alcohols; Biological Products; Biphenyl Compounds; Catechin; Catechols; Curcumin; Encephalitis; Fatty Alcohols; Ginsenosides; Glucosides; Microglia; Molecular Structure; Nerve Degeneration; Neuroprotective Agents; Phenyl Ethers; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Perspectives for production and application of resveratrol.
Topics: Bacterial Proteins; Biotechnology; Cells, Cultured; Gene Transfer Techniques; Molecular Structure; Plants; Resveratrol; Stilbenes | 2011 |
Polyphenols: planting the seeds of treatment for the metabolic syndrome.
Topics: Animals; Antioxidants; Catechin; Curcumin; Flavonoids; Humans; Metabolic Syndrome; Phenols; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2011 |
Mitochondrial protection by resveratrol.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Humans; Mice; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
Erratum to: resveratrol and red wine, healthy heart and longevity.
Topics: Aging; Antioxidants; Cardiotonic Agents; Health Status; Heart; Humans; Longevity; Resveratrol; Stilbenes; Wine | 2011 |
Resveratrol--pills to replace a healthy diet?
Topics: Aging; Antioxidants; Chronic Disease; Diet; Dietary Supplements; Food; Humans; Resveratrol; Stilbenes | 2011 |
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Diet; Flavonoids; Fruit; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Resveratrol; Rutin; Stilbenes; Vegetables | 2011 |
The immunomodulating activities of resveratrol glucosides in humans.
Topics: Anti-Inflammatory Agents; Antioxidants; Glucosides; Humans; Immunologic Factors; Patents as Topic; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Diet and thrombosis risk: nutrients for prevention of thrombotic disease.
Topics: Alcohol Drinking; Allium; Diet; Dietary Carbohydrates; Dietary Fats; Fatty Acids; Fatty Acids, Omega-3; Fibrinolytic Agents; Flavonoids; Ginkgo biloba; Humans; Methionine; Phenols; Platelet Activation; Platelet Aggregation; Polyphenols; Receptors, Calcitriol; Resveratrol; Solanum lycopersicum; Stilbenes; Thrombosis; Vitamin B Complex; Vitamin E; Vitamin K; Zingiber officinale | 2011 |
Phytochemicals resveratrol and sulforaphane as potential agents for enhancing the anti-tumor activities of conventional cancer therapies.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Isothiocyanates; Neoplasms; Resveratrol; Stilbenes; Sulfoxides; Thiocyanates | 2012 |
Natural products of dietary origin as lead compounds in virtual screening and drug design.
Topics: Animals; Biological Products; Caffeine; Curcumin; Diet; Drug Design; Genistein; Humans; Resveratrol; Stilbenes | 2012 |
Resveratrol and its analogues: promising antitumor agents.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Humans; Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Biological aspects of altered bone remodeling in multiple myeloma and possibilities of pharmacological intervention.
Topics: Antineoplastic Agents, Phytogenic; Bone and Bones; Bone Remodeling; Bone Resorption; Boronic Acids; Bortezomib; Calcium-Binding Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Multiple Myeloma; Osteoblasts; Osteoclasts; Protease Inhibitors; Pyrazines; Resveratrol; Signal Transduction; Stilbenes; Wnt Proteins | 2011 |
Synergism between resveratrol and other phytochemicals: implications for obesity and osteoporosis.
Topics: Adipocytes; Animals; Caloric Restriction; Drug Synergism; Humans; Lipolysis; Obesity; Osteoblasts; Osteoporosis; Resveratrol; Stilbenes | 2011 |
Promise of resveratrol for easing status epilepticus and epilepsy.
Topics: Animals; Epilepsy; Hippocampus; Humans; Resveratrol; Seizures; Status Epilepticus; Stilbenes | 2011 |
The controversial links among calorie restriction, SIRT1, and resveratrol.
Topics: Animals; Caloric Restriction; Gene Knockdown Techniques; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
The effects of the dietary polyphenol resveratrol on human healthy aging and lifespan.
Topics: Aging; Animals; Humans; Longevity; Models, Biological; Resveratrol; Sirtuins; Stilbenes | 2011 |
Role of membrane dynamics processes and exogenous molecules in cellular resveratrol uptake: consequences in bioavailability and activities.
Topics: Animals; Biological Availability; Biological Transport; Cell Membrane; Endocytosis; Fatty Acids; Humans; Integrin alphaVbeta3; Lipoproteins; Membrane Fluidity; Membrane Lipids; Membrane Microdomains; Resveratrol; Serum Albumin, Bovine; Stilbenes | 2011 |
New delivery systems to improve the bioavailability of resveratrol.
Topics: Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Humans; Resveratrol; Stilbenes | 2011 |
Resveratrol in cardiovascular disease: what is known from current research?
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Antioxidants; Cardiovascular Diseases; Heart Failure; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Resveratrol and health--a comprehensive review of human clinical trials.
Topics: Animals; Biological Availability; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Dietary Supplements; Humans; Liver; Obesity; Oxidative Stress; Resveratrol; Stilbenes; Wine | 2011 |
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol.
Topics: Humans; Resveratrol; Stilbenes | 2011 |
Endocrine-active chemicals in mammary cancer causation and prevention.
Topics: Animals; Anticarcinogenic Agents; Benzhydryl Compounds; Breast; Breast Neoplasms; Diethylstilbestrol; Endocrine Disruptors; Estrogens, Non-Steroidal; Female; Genistein; Humans; Phenols; Polychlorinated Dibenzodioxins; Resveratrol; Stilbenes | 2012 |
Caloric restriction and chronic inflammatory diseases.
Topics: Adaptive Immunity; Animals; Biomimetics; Caloric Restriction; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus; Humans; Immunity, Innate; Inflammation; Inflammation Mediators; Insulin-Like Growth Factor I; Metformin; Periodontitis; Resveratrol; Signal Transduction; Sirolimus; Sirtuins; Stilbenes; TOR Serine-Threonine Kinases | 2012 |
Calorie restriction and resveratrol in cardiovascular health and disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caloric Restriction; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes; Vasodilator Agents | 2011 |
The potential role of epigenetic responses to diet in ageing.
Topics: Aging; Caloric Restriction; Diet; DNA Methylation; Epigenesis, Genetic; Humans; Longevity; Plant Extracts; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
AMP-activated protein kinase: also regulated by ADP?
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Binding Sites; Electron Transport; Energy Metabolism; Enzyme Activation; Fungal Proteins; Glucose; Glycogen; Humans; Metformin; Mitochondria; Phosphorylation; Protein Conformation; Resveratrol; Stilbenes; Transcription, Genetic; Yeasts | 2011 |
Resveratrol in the prevention and treatment of coronary artery disease.
Topics: Animals; Cardiovascular System; Coronary Artery Disease; Humans; Lipid Peroxidation; Lipids; Macrophages; Metabolic Syndrome; Muscle, Smooth, Vascular; Myocardial Reperfusion; Plaque, Atherosclerotic; Resveratrol; Stilbenes; Thrombosis; Wine | 2011 |
Ageing skin: oestrogen receptor β agonists offer an approach to change the outcome.
Topics: Antioxidants; Estrogen Receptor beta; Estrogens; Humans; Isoflavones; Reactive Oxygen Species; Resveratrol; Skin Aging; Snail Family Transcription Factors; Stilbenes; Transcription Factor AP-1; Transcription Factors; Ultraviolet Rays | 2011 |
Innovative cosmeceuticals: sirtuin activators and anti-glycation compounds.
Topics: Antioxidants; Cosmetics; Enzyme Activators; Glycation End Products, Advanced; Humans; Plant Preparations; Resveratrol; Sirtuins; Skin Aging; Stilbenes | 2011 |
Hormesis, cell death and aging.
Topics: Aging; Animals; Autophagy; Caloric Restriction; Cell Death; Hormesis; Humans; Ischemic Preconditioning; Mitochondria; Resveratrol; Stilbenes | 2011 |
[Recent anti-aging studies on caloric restriction and resveratrol].
Topics: Aging; Animals; Caloric Restriction; Group III Histone Deacetylases; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
Resveratrol and its impact on aging and thyroid function.
Topics: Adenocarcinoma, Follicular; Aging; Humans; Mitogen-Activated Protein Kinases; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Thyroid Gland; Thyroid Neoplasms; Thyrotropin; Tumor Suppressor Protein p53 | 2011 |
Administration of resveratrol: What formulation solutions to bioavailability limitations?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ants; Biological Availability; Chemistry, Pharmaceutical; Humans; Protective Agents; Resveratrol; Stilbenes | 2012 |
Role of resveratrol and its analogues in the treatment of neurodegenerative diseases: focus on recent discoveries.
Topics: Animals; Brain; Drug Discovery; Humans; Neurodegenerative Diseases; Neurons; Resveratrol; Signal Transduction; Stilbenes; Treatment Outcome | 2011 |
5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Humans; Inflammation; Lipofuscin; Lysosomes; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Models, Biological; Oxidative Stress; Resveratrol; Retina; Retinal Pigment Epithelium; Stilbenes; TOR Serine-Threonine Kinases | 2011 |
Epigenetic diet: impact on the epigenome and cancer.
Topics: Anticarcinogenic Agents; Catechin; Curcumin; Diet; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genistein; Histones; Humans; Isothiocyanates; MicroRNAs; Neoplasms; Polyphenols; Resveratrol; Stilbenes; Tea | 2011 |
The biology of aging: 1985-2010 and beyond.
Topics: Aging; Animals; Caenorhabditis elegans; Caloric Restriction; Drosophila melanogaster; Epigenesis, Genetic; Free Radicals; Gene Expression; Humans; Life Expectancy; Longevity; Mice; Mitochondria; Regenerative Medicine; Resveratrol; Stem Cells; Stilbenes; Telomerase | 2011 |
Cellular and molecular effects of resveratrol in health and disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Neurodegenerative Diseases; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2012 |
Phytochemicals in cancer prevention and therapy: truth or dare?
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carotenoids; Catechin; Curcumin; Genistein; Humans; Isothiocyanates; Lycopene; Neoplasms; Resveratrol; Stilbenes | 2010 |
Age-related cardiovascular disease and the beneficial effects of calorie restriction.
Topics: Aged; Aging; Antimutagenic Agents; Caloric Restriction; Cardiovascular Diseases; Humans; Longevity; Resveratrol; Risk Factors; Stilbenes | 2012 |
Epigenetic treatment of neurological disease.
Topics: Alzheimer Disease; Butylamines; Cell Differentiation; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Huntington Disease; Hydroxamic Acids; Neurons; Phenylbutyrates; Protein Processing, Post-Translational; Resveratrol; Stilbenes; Valproic Acid; Vorinostat | 2011 |
Chemoprevention in colorectal cancer--where we stand and what we have learned from twenty year's experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticarcinogenic Agents; Colorectal Neoplasms; Histone Deacetylase Inhibitors; Humans; Metformin; Precancerous Conditions; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes | 2012 |
Antioxidant effects of resveratrol and other stilbene derivatives on oxidative stress and *NO bioavailability: Potential benefits to cardiovascular diseases.
Topics: Animals; Antioxidants; Arginine; Biological Availability; Cardiovascular Diseases; Diet, Atherogenic; Endothelium, Vascular; Fatty Acids; Humans; Mice; Nitric Oxide; Oxidative Stress; Polyphenols; Rabbits; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Wine | 2012 |
Red wine, grapes, and better health--resveratrol.
Topics: Anti-Inflammatory Agents; Humans; Oxidative Stress; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Vitis; Wine | 2011 |
[Chemoprevention of prostate cancer].
Topics: Animals; Anticarcinogenic Agents; Carotenoids; Curcumin; Humans; Isoflavones; Lycopene; Male; Prostatic Neoplasms; Resveratrol; Stilbenes; Vitamin E | 2011 |
Resveratrol, a neuroprotective supplement for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Humans; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes | 2012 |
Resveratrol in human cancer chemoprevention--choosing the 'right' dose.
Topics: Animals; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Neoplasms; Resveratrol; Stilbenes | 2012 |
Histone deacetylases and their role in asthma.
Topics: Anti-Inflammatory Agents; Asthma; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Resveratrol; Stilbenes | 2012 |
Cardiovascular effects and molecular targets of resveratrol.
Topics: Animals; Cardiovascular Agents; Cardiovascular Diseases; Humans; Molecular Targeted Therapy; Nitric Oxide; Resveratrol; Stilbenes | 2012 |
AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications.
Topics: AMP-Activated Protein Kinase Kinases; Genes, abl; Hematologic Neoplasms; Humans; Leukemia; Metformin; Phosphatidylinositol 3-Kinase; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2011 |
Alternative medicines as emerging therapies for inflammatory bowel diseases.
Topics: Adrenal Cortex Hormones; Animals; Clinical Trials as Topic; Complementary Therapies; Humans; Inflammatory Bowel Diseases; Phytotherapy; Plants; Resveratrol; Rutin; Stilbenes | 2012 |
Dietary polyphenols and obesity.
Topics: Adipogenesis; Animals; Anthocyanins; Catechin; Cells, Cultured; Curcumin; Diet; Energy Metabolism; Fruit; Humans; Obesity; Polyphenols; Resveratrol; Stilbenes; Tea | 2010 |
Resveratrol in medicinal chemistry: a critical review of its pharmacokinetics, drug-delivery, and membrane interactions.
Topics: Animals; Antioxidants; Cell Membrane; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Resveratrol; Stilbenes | 2012 |
Old wine in a new bottle: the Warburg effect and anticancer mechanisms of resveratrol.
Topics: Animals; Copper; Glycolysis; Humans; Hydrogen-Ion Concentration; Neoplasms; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Regulation of cell death and survival by resveratrol: implications for cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Cell Death; Cell Proliferation; Cell Survival; Humans; Neoplasms; Resveratrol; Stilbenes | 2012 |
Effects of elicitors, viticultural factors, and enological practices on resveratrol and stilbenes in grapevine and wine.
Topics: Animals; Antioxidants; Humans; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes; Vitis; Wine | 2012 |
Resveratrol in cancer: cellular and mitochondrial consequences of proton transport inhibition.
Topics: Antineoplastic Agents; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Proton-Translocating ATPases; Resveratrol; Stilbenes | 2012 |
Recent advances in the study on resveratrol.
Topics: Animals; Cyclooxygenase Inhibitors; Humans; Nitric Oxide Synthase Type III; Peroxisome Proliferator-Activated Receptors; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Sirtuins as regulators of metabolism and healthspan.
Topics: Aging; Animals; Energy Metabolism; Glucose; Histones; Homeostasis; Humans; Insulin; Insulin Secretion; Lipid Metabolism; Longevity; Multigene Family; NAD; Phylogeny; Protein Processing, Post-Translational; Resveratrol; Sirtuins; Stilbenes | 2012 |
[Resveratrol: a neuroprotective polyphenol in the Mediterranean diet].
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Biological Availability; Cardiotonic Agents; Cell Survival; Cerebrovascular Disorders; Diet, Mediterranean; DNA Repair; Humans; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Peripheral Nervous System Diseases; Reperfusion Injury; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes; Trauma, Nervous System; Vitis; Wine | 2012 |
Resveratrol: potential as anticancer agent.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Fallopia japonica; Humans; Neoplasms; Outcome Assessment, Health Care; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Vitis; Wine | 2012 |
The journey of resveratrol from yeast to human.
Topics: Aging; Animals; Caloric Restriction; Energy Metabolism; Enzyme Activation; Enzyme Activators; Evidence-Based Medicine; Fungal Proteins; Humans; Phosphodiesterase Inhibitors; Resveratrol; Sirtuin 1; Stilbenes; Yeasts | 2012 |
Resveratrol and diabetic cardiac function: focus on recent in vitro and in vivo studies.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Signaling System; Muscle Proteins; Myocardium; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Colorectal cancer chemoprevention by trans-resveratrol.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Precancerous Conditions; Resveratrol; Stilbenes | 2012 |
A patent review of sirtuin activators: an update.
Topics: Animals; Anti-Obesity Agents; Dietary Supplements; Drug Design; Enzyme Activation; Enzyme Activators; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Patents as Topic; Resveratrol; Sirtuin 1; Stilbenes; Structure-Activity Relationship | 2012 |
[Metabolic homeostasis as the cornerstone of aging].
Topics: Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; Cell Transformation, Neoplastic; Drosophila melanogaster; Energy Metabolism; Homeostasis; Humans; Insulin; Insulin-Like Growth Factor I; Longevity; Membrane Transport Proteins; Mice; Models, Biological; Neoplasms; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2012 |
The anticancer effects of resveratrol: modulation of transcription factors.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Humans; Neoplasms; NF-E2-Related Factor 2; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Transcription Factors | 2012 |
Control of MicroRNA expression as a new way for resveratrol to deliver its beneficial effects.
Topics: Animals; Gene Expression Regulation; Humans; MicroRNAs; Neoplasms; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2012 |
Resveratrol and health: the starting point.
Topics: Health; Humans; Metabolic Diseases; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Anti-inflammatory effects of resveratrol and its potential use in therapy of immune-mediated diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dendritic Cells; Humans; Immune System; Lymphocytes; Macrophages; Models, Immunological; Resveratrol; Signal Transduction; Stilbenes | 2012 |
[Resveratrol--phytophenol with wide activity].
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents; Atherosclerosis; Cardiovascular Diseases; Chemoprevention; Glucose; Humans; Longevity; Neoplasms; Neurodegenerative Diseases; Resveratrol; Stilbenes | 2012 |
Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cartilage, Articular; Chondrocytes; Curcumin; Humans; Inflammation; Interleukin-1beta; Joints; Osteoarthritis; Phytochemicals; Phytotherapy; Resveratrol; Stilbenes; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2012 |
Complementary and alternative medicines in prostate cancer: from bench to bedside?
Topics: Antioxidants; Beverages; Complementary Therapies; Curcuma; Humans; Lythraceae; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Tea; Vitamin E; Vitamins | 2012 |
Are sirtuins viable targets for improving healthspan and lifespan?
Topics: Aging; Animals; Biotransformation; Caloric Restriction; Geriatrics; Health; Heterocyclic Compounds, 4 or More Rings; Humans; Life Expectancy; Mammals; Resveratrol; Sirtuin 1; Sirtuin 3; Sirtuins; Stilbenes | 2012 |
Metabolic engineering of yeast and plants for the production of the biologically active hydroxystilbene, resveratrol.
Topics: Metabolic Engineering; Plants; Resveratrol; Stilbenes; Yeasts | 2012 |
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 33.
Topics: Animals; Antioxidants; Athletic Performance; Dietary Supplements; Humans; Models, Animal; Plant Extracts; Quercetin; Resveratrol; Rhodiola; Stilbenes | 2012 |
Pleiotropic protective effects of phytochemicals in Alzheimer's disease.
Topics: Alzheimer Disease; Catechin; Curcumin; Humans; Neuroprotective Agents; NF-E2-Related Factor 2; Polyphenols; Resveratrol; Stilbenes | 2012 |
Polyphenols: key issues involved in chemoprevention of prostate cancer.
Topics: Antioxidants; Catechin; Curcumin; Flavonoids; Genistein; Humans; Male; Polyphenols; Prostatic Neoplasms; Quercetin; Resveratrol; Stilbenes | 2012 |
The effect of resveratrol on longevity across species: a meta-analysis.
Topics: Algorithms; Animals; Bayes Theorem; Caloric Restriction; Diptera; Fishes; Fungi; Humans; Life Expectancy; Longevity; Mice; Models, Statistical; Nematoda; Proportional Hazards Models; Resveratrol; Stilbenes; Wine | 2012 |
Hibiscus sabdariffa Linnaeus (Malvaceae), curcumin and resveratrol as alternative medicinal agents against metabolic syndrome.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Curcumin; Hibiscus; Humans; Metabolic Syndrome; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2013 |
The neurobiology of sirtuins and their role in neurodegeneration.
Topics: Aging; Animals; Drug Discovery; Humans; Inflammation; Neurodegenerative Diseases; Resveratrol; Sirtuins; Stilbenes; Stress, Physiological; Yeasts | 2012 |
The bioavailability and distribution of trans-resveratrol are constrained by ABC transporters.
Topics: Animals; ATP-Binding Cassette Transporters; Biological Availability; Humans; Intestinal Absorption; Resveratrol; Stilbenes | 2012 |
Resveratrol biosynthesis: plant metabolic engineering for nutritional improvement of food.
Topics: Adaptation, Physiological; Diet; Fruit; Functional Food; Humans; Metabolic Engineering; Nutritive Value; Plants, Edible; Plants, Genetically Modified; Resveratrol; Stilbenes; Vegetables | 2012 |
Drug interaction potential of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Cardiotonic Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dietary Supplements; Enzyme Inhibitors; Food-Drug Interactions; Humans; Immunologic Factors; Resveratrol; Stilbenes; Vasodilator Agents; Wine | 2012 |
[Sirtuin1 and lung disease].
Topics: Animals; Asthma; Benzamides; Humans; Lung Diseases; Lung Neoplasms; Naphthols; Protein Processing, Post-Translational; Pulmonary Disease, Chronic Obstructive; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Derivatives of resveratrol: potential agents in prevention and treatment of cardiovascular disease.
Topics: AMP-Activated Protein Kinases; Apoptosis; Cardiovascular Agents; Cardiovascular Diseases; Humans; Hydroxamic Acids; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Dietary polyphenols and mechanisms of osteoarthritis.
Topics: Cartilage, Articular; Catechin; Citrus; Curcumin; Flavones; Genistein; Humans; Lythraceae; Osteoarthritis; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2012 |
Honeybees and cell lines as models of DNA methylation and aging in response to diet.
Topics: Age Factors; Aging; Animals; Bees; Caloric Restriction; Cell Line; Diet; DNA Methylation; Energy Metabolism; Fatty Acids; Gene Expression Regulation; Genotype; Humans; Longevity; Models, Animal; Phenotype; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Resveratrol in cholesterol metabolism and atherosclerosis.
Topics: Angiogenesis Modulating Agents; Animals; Antioxidants; Atherosclerosis; Cardiotonic Agents; Cholesterol; Dietary Supplements; Humans; Resveratrol; Stilbenes; Vasodilator Agents | 2012 |
Resveratrol as a calorie restriction mimetic: therapeutic implications.
Topics: Aging; Animals; Biomimetic Materials; Caloric Restriction; Humans; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia.
Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Colorectal Neoplasms; Curcumin; Dietary Supplements; Fatty Acids, Omega-3; Humans; Resveratrol; Stilbenes; Vitamin D | 2013 |
Dietary polyphenol-derived protection against neurotoxic β-amyloid protein: from molecular to clinical.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Catechin; Cell Line; Curcumin; Diet; Humans; Models, Molecular; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Plants; Polyphenols; Resveratrol; Stilbenes; Tea | 2012 |
The fetal origins of the metabolic syndrome: can we intervene?
Topics: Antioxidants; Ascorbic Acid; Diet Therapy; Dietary Supplements; Exenatide; Fatty Acids, Omega-3; Female; Fetal Growth Retardation; Folic Acid; Humans; Hypoglycemic Agents; Melatonin; Metabolic Syndrome; Micronutrients; Peptides; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Resveratrol; Stilbenes; Venoms | 2012 |
Resveratrol role in cardiovascular and metabolic health and potential mechanisms of action.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Autophagy; Cardiovascular Diseases; Disease Models, Animal; Humans; Metabolic Diseases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
Pancreatic cancer chemoprevention by phytochemicals.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Capsaicin; Curcumin; Humans; Isothiocyanates; Pancreatic Neoplasms; Phytochemicals; Resveratrol; Stilbenes; Tea | 2013 |
Resveratrol and related compounds as antioxidants with an allosteric mechanism of action in epigenetic drug targets.
Topics: Allosteric Regulation; AMP-Activated Protein Kinases; Animals; Antioxidants; Enzyme Activation; Enzyme Activators; Epigenesis, Genetic; Humans; Molecular Structure; Oxidative Stress; Phosphorylation; Resveratrol; Sirtuin 1; Stilbenes; Structure-Activity Relationship | 2013 |
Glucan–resveratrol–vitamin C combination offers protection against toxic agents.
Topics: Animals; Ascorbic Acid; Drug Combinations; Environmental Pollutants; Glucans; Humans; Immune System; Immunity, Cellular; Immunity, Humoral; Neoplasms; Protective Agents; Resveratrol; Stilbenes; Thimerosal | 2012 |
From resveratrol to its derivatives: new sources of natural antioxidant.
Topics: Antioxidants; Brain Diseases; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes | 2013 |
Differential action of phytochemicals on platelet apoptosis: a biological overview.
Topics: Apoptosis; Benzoquinones; Blood Platelets; Humans; Plant Extracts; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Energy restriction: stepping stones towards cancer therapy.
Topics: AMP-Activated Protein Kinase Kinases; Antineoplastic Agents; Energy Metabolism; Enzyme Inhibitors; Hexokinase; Humans; Molecular Targeted Therapy; Neoplasms; Protein Kinases; Resveratrol; Stilbenes; Thiazolidinediones | 2012 |
Targeting mTOR: evaluating the therapeutic potential of resveratrol for cancer treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Humans; Molecular Targeted Therapy; Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Curcuminoids and resveratrol as anti-Alzheimer agents.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Antioxidants; Curcumin; Diarylheptanoids; Humans; Male; Resveratrol; Stilbenes; tau Proteins | 2012 |
[Effect of resveratrol on the fundus oculi. An overview].
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Fundus Oculi; Humans; Models, Biological; NF-kappa B; Resveratrol; Retina; Signal Transduction; Stilbenes | 2013 |
Resveratrol and cancer treatment: is hormesis a yet unsolved matter?
Topics: Animals; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Hormesis; Humans; Neoplasms; Resveratrol; Stilbenes | 2013 |
Diabetic complications in pregnancy: is resveratrol a solution?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Complications; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Humans; Hypoglycemic Agents; Pregnancy; Pregnancy in Diabetics; Resveratrol; Stilbenes | 2013 |
Resveratrol and clinical trials: the crossroad from in vitro studies to human evidence.
Topics: Animals; Anticarcinogenic Agents; Cardiovascular Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Evidence-Based Medicine; Humans; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Tissue Distribution; Treatment Outcome | 2013 |
Bioactive polyphenols from grapes and wine emphasized with resveratrol.
Topics: Animals; Biological Availability; Humans; Plants, Edible; Resveratrol; Stilbenes; Vitis; Wine | 2013 |
[The application of resveratrol in treating rheumatic disease: a review].
Topics: Animals; Humans; Phytotherapy; Resveratrol; Rheumatic Diseases; Stilbenes | 2012 |
Oxidative stress and potential applications of free radical scavengers in glaucoma.
Topics: Animals; Antioxidants; Apoptosis; DNA; Free Radical Scavengers; Ginkgo biloba; Glaucoma; Humans; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Resveratrol; Stilbenes; Sulfonamides; Thiophenes | 2013 |
Modulation of adipose tissue inflammation by bioactive food compounds.
Topics: Adipose Tissue; Curcumin; Endocrine Glands; Fatty Acids; Food; Humans; Inflammation; Insulin Resistance; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2013 |
Resveratrol: new avenues for a natural compound in neuroprotection.
Topics: Aging; Animals; Antioxidants; Autophagy; Biological Products; Humans; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Nutraceuticals as new treatment approaches for oral cancer: II. Green tea extracts and resveratrol.
Topics: Animals; Catechin; Dietary Supplements; Humans; Mice; Mouth Neoplasms; Plant Extracts; Resveratrol; Stilbenes; Tea | 2013 |
Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties.
Topics: Aging; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Benzofurans; Dibenzocycloheptenes; Dietary Supplements; Humans; Plants; Resorcinols; Resveratrol; Rodentia; Stilbenes | 2013 |
Focus on: The cardiovascular system: what did we learn from the French (Paradox)?
Topics: Alcohol Drinking; Alcoholic Beverages; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Binge Drinking; Cardiovascular Diseases; Cardiovascular System; Humans; Resveratrol; Stilbenes; Wine | 2010 |
Resveratrol vs. calorie restriction: data from rodents to humans.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Caloric Restriction; Dietary Supplements; Energy Metabolism; Humans; Insulin Resistance; Longevity; Oxidative Stress; Resveratrol; Risk Reduction Behavior; Rodentia; Sirtuin 1; Stilbenes | 2013 |
Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2.
Topics: Antioxidants; Catechin; Diet Therapy; Disulfides; Gene Expression Regulation; Humans; Inflammation; NF-E2-Related Factor 2; Resveratrol; Signal Transduction; Stilbenes; Sulfinic Acids | 2013 |
[Advance of resveratrol in treating diabetes mellitus].
Topics: Animals; Diabetes Mellitus, Experimental; Insulin Resistance; Resveratrol; Stilbenes | 2013 |
Effects of dietary phytophenols on the expression of microRNAs involved in mammalian cell homeostasis.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cell Differentiation; Cell Physiological Phenomena; Diet; Dietary Fiber; Fruit; Gene Expression; Homeostasis; Humans; Inflammation; MicroRNAs; Neoplasms; Phenols; Plants; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Vegetables | 2013 |
Resveratrol and analogues: a review of antioxidant activity and applications to human health.
Topics: Antioxidants; Biological Availability; Diet; Dietary Supplements; Humans; Patents as Topic; Plant Extracts; Resveratrol; Stilbenes | 2013 |
[Advance of studies on effect of resveratrol on activity of cytochrome P450].
Topics: Animals; Clinical Trials as Topic; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Humans; Resveratrol; Stilbenes | 2013 |
Review of recent data on the metabolism, biological effects, and toxicity of resveratrol in humans.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Glucose; Humans; Lipid Metabolism; Neoplasms; Resveratrol; Stilbenes | 2014 |
Neuroprotective properties and mechanisms of resveratrol in in vitro and in vivo experimental cerebral stroke models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Biological Availability; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Gerbillinae; Humans; Mice; Neuroprotective Agents; Oxidative Stress; Rats; Resveratrol; Stilbenes; Stroke | 2013 |
Protection of dietary polyphenols against oral cancer.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Biological Availability; Chemoprevention; Diet; Ellagic Acid; Flavonoids; Humans; Mouth Neoplasms; Phytotherapy; Polyphenols; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Tea | 2013 |
Regulating miRNA by natural agents as a new strategy for cancer treatment.
Topics: Animals; Antineoplastic Agents; Carotenoids; Catechin; Curcumin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lycopene; MicroRNAs; Molecular Targeted Therapy; Neoplasms; Neoplastic Stem Cells; Resveratrol; Stilbenes | 2013 |
What is new for resveratrol? Is a new set of recommendations necessary?
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Neoplasms; Practice Guidelines as Topic; Resveratrol; Stilbenes | 2013 |
Resveratrol in the management of human cancer: how strong is the clinical evidence?
Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Disease Management; Dose-Response Relationship, Drug; Humans; Neoplasms; Resveratrol; Stilbenes | 2013 |
Resveratrol analogs: promising chemopreventive agents.
Topics: Animals; Antineoplastic Agents; Chemoprevention; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
Resveratrol and its metabolites modulate cytokine-mediated induction of eotaxin-1 in human pulmonary artery endothelial cells.
Topics: Chemokine CCL11; Cytokines; Endothelial Cells; Humans; Inflammation Mediators; Pulmonary Artery; Resveratrol; Stilbenes | 2013 |
Resveratrol in primary and secondary prevention of cardiovascular disease: a dietary and clinical perspective.
Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Primary Prevention; Resveratrol; Secondary Prevention; Stilbenes; Vitis; Wine | 2013 |
Evidence for circulatory benefits of resveratrol in humans.
Topics: Animals; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes; Vasodilator Agents | 2013 |
Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis.
Topics: Animals; Bone Density; Estrogen Replacement Therapy; Humans; Osteocytes; Osteoporosis; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Resveratrol in mammals: effects on aging biomarkers, age-related diseases, and life span.
Topics: Aging; Animals; Antioxidants; Biomarkers; Cardiovascular Diseases; Humans; Longevity; Mammals; Resveratrol; Stilbenes | 2013 |
Resveratrol in metabolic health: an overview of the current evidence and perspectives.
Topics: Animals; Caloric Restriction; Clinical Trials as Topic; Dietary Supplements; Energy Metabolism; Humans; Metabolic Diseases; Obesity; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits?
Topics: Animals; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Energy Metabolism; Humans; Insurance Benefits; Obesity; Resveratrol; Stilbenes | 2013 |
Importance of lipid microdomains, rafts, in absorption, delivery, and biological effects of resveratrol.
Topics: Absorption; Animals; Apoptosis; Drug Delivery Systems; Humans; Lipid Metabolism; Membrane Microdomains; Neoplasms; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Interplay between metabolism and transport of resveratrol.
Topics: Animals; Biological Transport; Cell Line, Tumor; Energy Metabolism; Humans; Resveratrol; Stilbenes; Tissue Distribution | 2013 |
Nano- and micro-encapsulated systems for enhancing the delivery of resveratrol.
Topics: Animals; Capsules; Drug Compounding; Drug Delivery Systems; Humans; Liposomes; Nanocapsules; Resveratrol; Stilbenes | 2013 |
Resveratrol-based combinatorial strategies for cancer management.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combinatorial Chemistry Techniques; Disease Management; Humans; Neoplasms; Resveratrol; Stilbenes | 2013 |
An adipocentric perspective of resveratrol as a calorie restriction mimetic.
Topics: Adipose Tissue; Adiposity; Animals; Biomimetic Materials; Caloric Restriction; Humans; Obesity; Resveratrol; Stilbenes | 2013 |
The pig as a valuable model for testing the effect of resveratrol to prevent cardiovascular disease.
Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Disease Models, Animal; Humans; Resveratrol; Species Specificity; Stilbenes; Swine; Treatment Outcome | 2013 |
Resveratrol, from experimental data to nutritional evidence: the emergence of a new food ingredient.
Topics: Animals; Biomedical Research; Caloric Restriction; Cardiovascular Diseases; Dietary Supplements; Food; Humans; Nutritional Status; Resveratrol; Statistics as Topic; Stilbenes | 2013 |
New role of silent information regulator 1 in cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Caloric Restriction; Forkhead Box Protein O1; Forkhead Transcription Factors; Histone Deacetylases; Homeostasis; Humans; Ion Channels; Ischemic Preconditioning; Mitochondrial Proteins; Molecular Targeted Therapy; Neuroprotective Agents; NF-kappa B; PPAR gamma; Protein Processing, Post-Translational; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Uncoupling Protein 2 | 2013 |
Antioxidant effects of resveratrol in cardiovascular, cerebral and metabolic diseases.
Topics: Antioxidants; Biological Availability; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Diabetes Mellitus; Humans; Metabolic Diseases; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes | 2013 |
The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Humans; Immune Tolerance; Macrophages; Resveratrol; Sirtuin 1; Stilbenes; T-Lymphocytes | 2013 |
Medicinal chemistry of the epigenetic diet and caloric restriction.
Topics: Aging; Anticarcinogenic Agents; Caloric Restriction; Catechin; Chemistry, Pharmaceutical; Curcumin; Epigenesis, Genetic; Humans; Isothiocyanates; Resveratrol; Stilbenes; Sulfoxides | 2013 |
Complementary and alternative medicine (CAM) in prostate and bladder cancer.
Topics: Acupuncture; Antineoplastic Agents; Antioxidants; Camellia sinensis; Complementary Therapies; Drugs, Chinese Herbal; Female; Humans; Male; Plant Extracts; Prostatic Neoplasms; Resveratrol; Selenium; Silybin; Silymarin; Stilbenes; Urinary Bladder Neoplasms; Vitamin E; Vitamins | 2013 |
Resveratrol: therapeutic potential for improving cardiometabolic health.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Glucose Metabolism Disorders; Humans; Inflammation; Oxidative Stress; Resveratrol; Stilbenes | 2013 |
Resveratrol derivatives: a patent review (2009 - 2012).
Topics: Animals; Antineoplastic Agents, Phytogenic; Cosmetics; Dietary Supplements; Drug Design; Humans; Patents as Topic; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
mTOR: more targets of resveratrol?
Topics: Animals; Humans; Protein Kinase Inhibitors; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Polyphenols: benefits to the cardiovascular system in health and in aging.
Topics: Aging; Animals; Cardiovascular System; Catechin; Curcumin; Diet; Disease Models, Animal; Fruit; Heart Diseases; Humans; Olive Oil; Plant Oils; Polyphenols; Quercetin; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Chemoprevention of skin melanoma: facts and myths.
Topics: Aminoquinolines; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Chemoprevention; Curcumin; Flavonoids; Humans; Imiquimod; Melanoma; Melanoma, Cutaneous Malignant; Pigmentation; Randomized Controlled Trials as Topic; Resveratrol; Retinoids; Risk; Skin; Skin Neoplasms; Stilbenes; Tea; Treatment Outcome; Vitamin D | 2013 |
Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1.
Topics: Animals; Curcumin; Enzyme Induction; Heme Oxygenase-1; Humans; Metabolic Diseases; Resveratrol; Stilbenes | 2013 |
Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Bezafibrate; Disease Models, Animal; Energy Metabolism; Mitochondria; Mitochondrial Diseases; Mitochondrial Turnover; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Ribonucleotides; Sirtuin 1; Stilbenes; Transcription Factors; Up-Regulation | 2014 |
Effects of resveratrol supplementation on plasma lipids: a systematic review and meta-analysis of randomized controlled trials.
Topics: Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Humans; Lipid Metabolism; Lipids; Randomized Controlled Trials as Topic; Resveratrol; Risk Factors; Stilbenes; Triglycerides | 2013 |
Resveratrol: from basic studies to bedside.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomedical Research; Cellular Senescence; Clinical Trials as Topic; Humans; Neoplasms; Resveratrol; Stilbenes | 2014 |
Toxicological and pharmacological concerns on oxidative stress and related diseases.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzopyrans; Carbazoles; Carvedilol; Diabetes Mellitus; Disease Models, Animal; Ethanolamines; Humans; Hydrogen Peroxide; Inflammatory Bowel Diseases; Nebivolol; Neoplasms; Neurodegenerative Diseases; Osteoporosis; Oxidative Stress; Propanolamines; Reactive Oxygen Species; Resveratrol; Stilbenes; Vascular Diseases | 2013 |
Chemoprevention of prostate cancer by major dietary phytochemicals.
Topics: Animals; Anticarcinogenic Agents; Capsaicin; Carotenoids; Chemoprevention; Curcumin; Humans; Lycopene; Male; Phytochemicals; Prostatic Neoplasms; Resveratrol; Stilbenes | 2013 |
Small-molecule allosteric activators of sirtuins.
Topics: Allosteric Regulation; Animals; Benzimidazoles; Disease Models, Animal; Humans; Inflammation; Molecular Targeted Therapy; Resveratrol; Sirtuins; Stilbenes | 2014 |
Cyclodextrins and antioxidants.
Topics: Antioxidants; Biological Availability; Carotenoids; Cyclodextrins; Diet; Dietary Supplements; Fatty Acids; Food Industry; Functional Food; Humans; Maillard Reaction; Resveratrol; Starch; Stilbenes; Ubiquinone; Vitamins | 2014 |
Neuroprotection by resveratrol in diabetic neuropathy: concepts & mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diabetic Neuropathies; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2013 |
Resveratrol: a unique antioxidant offering a multi-mechanistic approach for treating aging skin.
Topics: Administration, Cutaneous; Animals; Antioxidants; Humans; Mitochondria; Resveratrol; Signal Transduction; Skin Aging; Stilbenes | 2013 |
Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds.
Topics: Adipokines; Animals; Carotenoids; Curcumin; Fatty Acids, Omega-3; Fatty Liver; Flavonols; Humans; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Polyphenols; Resveratrol; Stilbenes | 2014 |
Novel insights of dietary polyphenols and obesity.
Topics: Adipocytes; Animals; Catechin; Cell Differentiation; Curcumin; Diet; Humans; Obesity; Plant Extracts; Polyphenols; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Tea | 2014 |
Prodrugs of quercetin and resveratrol: a strategy under development.
Topics: Animals; Antioxidants; Humans; Prodrugs; Quercetin; Resveratrol; Stilbenes | 2014 |
Chemistry, stability and bioavailability of resveratrol.
Topics: Biological Availability; Molecular Structure; Photochemical Processes; Resveratrol; Stereoisomerism; Stilbenes | 2014 |
Resveratrol in peanuts.
Topics: Alzheimer Disease; Antioxidants; Arachis; Biological Availability; Cardiovascular Diseases; Diet; Humans; Neoplasms; Resveratrol; Stilbenes | 2014 |
Potential of resveratrol in the treatment of heart failure.
Topics: Animals; Cardiotonic Agents; Heart Failure; Humans; Resveratrol; Stilbenes; Vitis | 2014 |
Synergistic effect of resveratrol and radiotherapy in control of cancers.
Topics: Animals; Apoptosis; Cell Proliferation; Chemoradiotherapy; Humans; Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Stilbenes | 2013 |
Renal protective effects of resveratrol.
Topics: Animals; Cytoprotection; Humans; Kidney; Models, Biological; Protective Agents; Resveratrol; Stilbenes | 2013 |
Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals.
Topics: Biological Availability; Catechin; Curcumin; Emulsions; Lactic Acid; Liposomes; Micelles; Nanoparticles; Nanotechnology; Phytochemicals; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Resveratrol; Solubility; Stilbenes | 2014 |
Dietary restriction and the pursuit of effective mimetics.
Topics: Animals; Caloric Restriction; Energy Intake; Genetic Variation; Health; Humans; Longevity; Metformin; Resveratrol; Sirolimus; Stilbenes | 2014 |
Resveratrol-sulfates provide an intracellular reservoir for generation of parent resveratrol, which induces autophagy in cancer cells.
Topics: Animals; Anticarcinogenic Agents; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Humans; Intracellular Space; Resveratrol; Stilbenes; Sulfates | 2014 |
Can resveratrol help to maintain metabolic health?
Topics: Adipose Tissue; Diabetes Mellitus, Type 2; Energy Metabolism; Enzyme Activators; Exercise; Humans; Mitochondria; Muscle, Skeletal; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Military aircrew and noise-induced hearing loss: prevention and management.
Topics: Acetylcarnitine; Acetylcysteine; Aerospace Medicine; Aircraft; Anti-Inflammatory Agents; Antioxidants; Azoles; Creatine; Ear Protective Devices; Equipment Design; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Genetic Therapy; Hair Cells, Auditory; Head Protective Devices; Hearing Loss, Noise-Induced; Humans; Hyperbaric Oxygenation; Isoindoles; Magnesium; Methionine; Military Personnel; Nanomedicine; Neuroprotective Agents; Organoselenium Compounds; Regeneration; Resveratrol; Salicylic Acid; Stilbenes; Vitamins | 2013 |
Exercise- and resveratrol-mediated alterations in adipose tissue metabolism.
Topics: Adipose Tissue; Animals; Exercise; Gene Expression Regulation; Glucose; Homeostasis; Humans; Mitochondria; Resveratrol; Stilbenes; Thiazolidinediones | 2014 |
Resveratrol: why is it a promising therapy for chronic kidney disease patients?
Topics: Humans; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Oxidative Stress; Renal Insufficiency, Chronic; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Resveratrol and cancer: focus on in vivo evidence.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Resveratrol; Stilbenes | 2014 |
Pharmacologic neuroprotective strategies in neonatal brain injury.
Topics: Acetylcysteine; Allopurinol; Antioxidants; Ascorbic Acid; Biopterins; Erythropoietin; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Fructose; Humans; Hypoxia-Ischemia, Brain; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Melatonin; Memantine; Neuroprotective Agents; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Topiramate; Vitamin E; Xenon | 2014 |
Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Cell Transformation, Neoplastic; Cellular Reprogramming; Curcumin; Humans; Neoplasms; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Quercetin; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2015 |
New and emerging regulators of intestinal lipoprotein secretion.
Topics: Animals; Apolipoprotein B-100; Apolipoprotein B-48; Atherosclerosis; Bile Acids and Salts; Cholesterol; Chylomicrons; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Fats; Dipeptidyl-Peptidase IV Inhibitors; Drug Evaluation, Preclinical; Dyslipidemias; Exenatide; Fatty Acids, Nonesterified; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Humans; Incretins; Insulin; Insulin Resistance; Intestine, Small; Lipoproteins; Microbiota; Peptides; Receptors, Glucagon; Resveratrol; Secretory Rate; Stilbenes; Triglycerides; Venoms | 2014 |
Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much?
Topics: Animals; Diabetes Complications; Humans; Intracellular Signaling Peptides and Proteins; Isothiocyanates; Kelch-Like ECH-Associated Protein 1; Leupeptins; Mice; Mice, Knockout; Molecular Targeted Therapy; NF-E2-Related Factor 2; Oleanolic Acid; Oxidative Stress; Resveratrol; Stilbenes; Sulfoxides | 2014 |
Modulation of adiponectin as a potential therapeutic strategy.
Topics: Adiponectin; Antihypertensive Agents; Atherosclerosis; Bariatric Surgery; Cardiovascular Diseases; Clinical Trials as Topic; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Reducing; Exercise; Humans; Hypoglycemic Agents; Insulin Resistance; Life Style; Metabolic Syndrome; Metabolism, Inborn Errors; Obesity; Peroxisome Proliferator-Activated Receptors; Receptors, Adiponectin; Resveratrol; Stilbenes | 2014 |
Resveratrol and the eye: activity and molecular mechanisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Eye Diseases; Humans; Resveratrol; Stilbenes; Vasodilator Agents; Wine | 2014 |
Nutrition: the future of melanoma prevention?
Topics: Antioxidants; Carotenoids; Catechin; Diet; Grape Seed Extract; Humans; Lycopene; Melanoma; Nutrition Policy; Proanthocyanidins; Resveratrol; Selenium; Skin Neoplasms; Stilbenes; Vitamin D; Vitamin E | 2014 |
The multiple mechanisms of cell death triggered by resveratrol in lymphoma and leukemia.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Humans; Leukemia; Lymphoma; Models, Biological; Resveratrol; Stilbenes | 2014 |
Could resveratrol be a useful drug for the treatment of malignant hemopathies?
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Drug Therapy, Combination; Hematologic Neoplasms; Humans; Neoplasms; Patents as Topic; Resveratrol; Stilbenes | 2014 |
Resveratrol as promising natural radioprotector. A review.
Topics: Antioxidants; Cell Survival; DNA Damage; Humans; Oxidation-Reduction; Radiation Injuries; Radiation-Protective Agents; Resveratrol; Stilbenes | 2013 |
Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials.
Topics: Diabetes Mellitus, Type 2; Dietary Supplements; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin Resistance; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2014 |
AMPK at the nexus of energetics and aging.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Aspirin; Energy Metabolism; Humans; Metabolic Diseases; Metformin; Mitochondria; Neoplasms; Resveratrol; Stilbenes | 2014 |
Effect of resveratrol on blood pressure: a meta-analysis of randomized controlled trials.
Topics: Blood Pressure; Diastole; Dose-Response Relationship, Drug; Humans; MEDLINE; Randomized Controlled Trials as Topic; Regression Analysis; Resveratrol; Stilbenes; Systole | 2015 |
Resveratrol oligomers for the prevention and treatment of cancers.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Humans; Neoplasms; Polymers; Resveratrol; Stilbenes | 2014 |
Resveratrol: review on therapeutic potential and recent advances in drug delivery.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Resveratrol; Stilbenes | 2014 |
Resveratrol and diabetes.
Topics: Animals; Diabetes Mellitus; Humans; Hypoglycemic Agents; Plant Extracts; Resveratrol; Stilbenes | 2013 |
From French Paradox to cancer treatment: anti-cancer activities and mechanisms of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; France; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes; Wine | 2014 |
Resveratrol in epilepsy: preventive or treatment opportunities?
Topics: Animals; Anticonvulsants; Antioxidants; Disease Models, Animal; Epilepsy; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2014 |
Resveratrol and calcium signaling: molecular mechanisms and clinical relevance.
Topics: Animals; Autoimmune Diseases; Calcium Signaling; Humans; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Targeting cancer with nano-bullets: curcumin, EGCG, resveratrol and quercetin on flying carpets.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cell Transformation, Neoplastic; Curcumin; Drug Carriers; Humans; Lactic Acid; Mice; Nanoparticles; Neoplasms; Phytochemicals; Polyglycolic Acid; Polyhydroxyethyl Methacrylate; Polylactic Acid-Polyglycolic Acid Copolymer; Quercetin; Resveratrol; Silicon Dioxide; Stilbenes; Xenograft Model Antitumor Assays | 2014 |
Resveratrol as a protective molecule for neuroinflammation: a review of mechanisms.
Topics: Animals; Humans; Inflammation; Models, Biological; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Stilbenes | 2014 |
Effects of resveratrol and other polyphenols in hepatic steatosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Hypolipidemic Agents; Lipid Metabolism; Liver; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Extracts; Plants, Medicinal; Polyphenols; Quercetin; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
Improving the efficacy of plant polyphenols.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Humans; Mitochondria; Plants; Polyphenols; Prodrugs; Quercetin; Reactive Oxygen Species; Resveratrol; Solubility; Stilbenes | 2014 |
Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress.
Topics: Animals; Anti-Inflammatory Agents; Capsaicin; Catechin; Colchicine; Curcumin; Humans; Imidazoles; Inflammation; Niacin; Resveratrol; Stilbenes | 2014 |
Use of microRNAs in directing therapy and evaluating treatment response in colorectal cancer.
Topics: Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; MicroRNAs; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Resveratrol; Stilbenes | 2014 |
[Advances of resveratrol synthase gene in the application of genetic engineering and biofunctional investigation].
Topics: Acyltransferases; Genetic Engineering; Plants, Genetically Modified; Resveratrol; Stilbenes | 2014 |
Sirtuins and resveratrol-derived compounds: a model for understanding the beneficial effects of the Mediterranean diet.
Topics: Diet, Mediterranean; Gastrointestinal Tract; Humans; Resveratrol; Signal Transduction; Sirtuins; Stem Cells; Stilbenes | 2014 |
Resveratrol as a gene regulator in the vasculature.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Endothelium, Vascular; Gene Expression Regulation; Humans; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders.
Topics: Acetylcarnitine; Alzheimer Disease; Brain; Brain Injuries; Cinnamates; Cognition Disorders; Curcumin; Depsides; Diet; Dietary Supplements; Fatty Acids, Omega-3; Humans; Neurodegenerative Diseases; Oxidative Stress; Polyphenols; Resveratrol; Rosmarinic Acid; Stilbenes | 2014 |
The controversial world of sirtuins.
Topics: Aging; Animals; Caloric Restriction; Epigenesis, Genetic; Humans; Longevity; Resveratrol; Sirtuins; Stilbenes | 2014 |
Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus--systematic review and meta-analysis.
Topics: Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Databases, Factual; Diabetes Mellitus, Type 2; Dietary Supplements; Glycated Hemoglobin; Humans; Insulin; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Triglycerides | 2015 |
Novel strategies for preventing diabetes and obesity complications with natural polyphenols.
Topics: Adipocytes; Animals; Diabetes Mellitus; Glucose; Humans; Hypoglycemic Agents; Insulin Resistance; Obesity; Polyphenols; Resveratrol; Stilbenes | 2015 |
Resveratrol and cardiovascular health--promising therapeutic or hopeless illusion?
Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes | 2014 |
Biocatalysis and biotransformation of resveratrol in microorganisms.
Topics: Acyltransferases; Biocatalysis; Biotransformation; Escherichia coli; Glucosides; Industrial Microbiology; Metabolic Engineering; Metabolic Networks and Pathways; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2015 |
Mediterranean Way of Drinking and Longevity.
Topics: Alcohol Drinking; Cardiovascular Diseases; Diet, Mediterranean; Female; Flavonols; Humans; Liver Cirrhosis; Longevity; Male; Mediterranean Region; Neoplasms; Phenols; Resveratrol; Risk Factors; Sex Factors; Sirtuins; Stilbenes; Wine | 2016 |
Recent advances of resveratrol in nanostructured based delivery systems and in the management of HIV/AIDS.
Topics: Acquired Immunodeficiency Syndrome; Antioxidants; Drug Delivery Systems; HIV Infections; Humans; Nanostructures; Resveratrol; Stilbenes | 2014 |
Resveratrol and stroke: from chemistry to medicine.
Topics: Animals; Antioxidants; Biological Availability; Humans; Resveratrol; Stilbenes; Stroke | 2014 |
Experimental studies of the molecular pathways regulated by exercise and resveratrol in heart, skeletal muscle and the vasculature.
Topics: Animals; Blood Vessels; Exercise; Heart; Humans; Muscle, Skeletal; Resveratrol; Stilbenes | 2014 |
Resveratrol, inositol, vitamin D and K in the prevention of cardiovascular and osteoporotic risk: a novel approach in peri- and postmenopause.
Topics: Animals; Cardiovascular Diseases; Cell Line; Female; Humans; Inositol; Mice; Osteoporosis, Postmenopausal; Perimenopause; Postmenopause; Resveratrol; Risk Factors; Stilbenes; Vitamin D; Vitamin K | 2014 |
The role of phytochemicals as micronutrients in health and disease.
Topics: Cardiovascular Diseases; Catechin; Clinical Trials as Topic; Curcuma; Curcumin; Dementia; Diabetes Mellitus; Humans; Micronutrients; Neoplasms; Phytochemicals; Plant Extracts; Resveratrol; Stilbenes; Tea; Vitis; Wine | 2014 |
Regulation of microRNAs by natural agents: new strategies in cancer therapies.
Topics: Antineoplastic Agents; Biological Products; Biomarkers, Tumor; Catechin; Curcumin; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplasms; Resveratrol; RNA Stability; Stilbenes | 2014 |
Resveratrol-mediated reversal of tumor multi-drug resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Resveratrol; Stilbenes | 2014 |
Anti-aging diet and supplements: fact or fiction?
Topics: Aging; Antioxidants; Caloric Restriction; Chronic Disease; Deception; Dietary Supplements; Evidence-Based Medicine; Functional Food; Health Promotion; Hormone Replacement Therapy; Humans; Resveratrol; Stilbenes; Vitamins | 2014 |
Neuroprotective action of resveratrol.
Topics: Animals; Antioxidants; Apoptosis; Humans; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes; Synapses | 2015 |
Resveratrol and endothelial nitric oxide.
Topics: Animals; Cardiovascular Diseases; Endothelial Cells; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Binding; Resveratrol; Stilbenes | 2014 |
Dietary polyphenols for treatment of Alzheimer's disease--future research and development.
Topics: Alzheimer Disease; Animals; Coumaric Acids; Curcumin; Diet; Flavonoids; Humans; Research; Resveratrol; Stilbenes | 2014 |
The molecular targets of resveratrol.
Topics: AMP-Activated Protein Kinases; Animals; Humans; Mitochondria; NF-kappa B; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Transcriptional Activation | 2015 |
Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment.
Topics: Alzheimer Disease; Amyloid; Animals; Humans; Polyphenols; Resveratrol; Stilbenes; Vitis | 2015 |
Resveratrol supplementation affects bone acquisition and osteoporosis: Pre-clinical evidence toward translational diet therapy.
Topics: Animals; Dietary Supplements; Drug Evaluation, Preclinical; Estrogens; Humans; Osteogenesis; Osteoporosis; Resveratrol; Stilbenes | 2015 |
MTA family of proteins in prostate cancer: biology, significance, and therapeutic opportunities.
Topics: Animals; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Male; Mice; Molecular Targeted Therapy; Neovascularization, Pathologic; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Stilbenes; Trans-Activators | 2014 |
Resveratrol and its oligomers: modulation of sphingolipid metabolism and signaling in disease.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Cardiovascular Diseases; Drug Discovery; Humans; Molecular Docking Simulation; Molecular Structure; Neoplasms; Neurodegenerative Diseases; Resveratrol; Signal Transduction; Sphingolipids; Stilbenes | 2014 |
Compared binding properties between resveratrol and other polyphenols to plasmatic albumin: consequences for the health protecting effect of dietary plant microcomponents.
Topics: Binding Sites; Diet; Flavonoids; Food; Health; Humans; Plants, Edible; Polyphenols; Resveratrol; Serum Albumin; Stilbenes | 2014 |
Enhancing the delivery of resveratrol in humans: if low bioavailability is the problem, what is the solution?
Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Humans; Nanotechnology; Resveratrol; Stilbenes | 2014 |
Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer.
Topics: Acetophenones; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Benzopyrans; Cell Line, Tumor; Curcumin; Gene Expression Regulation, Neoplastic; Genistein; Humans; Membrane Proteins; Neoplasms; Polyphenols; Quercetin; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Resveratrol: anti-obesity mechanisms of action.
Topics: Adipocytes; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; CCAAT-Enhancer-Binding Proteins; Down-Regulation; Fatty Acids; Humans; Lipogenesis; Liver; Muscle, Skeletal; Obesity; PPAR gamma; Resveratrol; Stilbenes | 2014 |
A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma.
Topics: Anticarcinogenic Agents; Carcinoma, Squamous Cell; Chemoprevention; Ethanol; Genetic Predisposition to Disease; Head and Neck Neoplasms; Humans; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes | 2015 |
Resveratrol and diabetes: from animal to human studies.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin-Secreting Cells; Liver; Muscle, Skeletal; Resveratrol; Stilbenes; Translational Research, Biomedical | 2015 |
Resveratrol and obesity: Can resveratrol relieve metabolic disturbances?
Topics: Adipose Tissue, Brown; AMP-Activated Protein Kinases; Animals; Humans; Mitochondria; Obesity; Resveratrol; Sirtuins; Stilbenes | 2015 |
Resveratrol and cancer: Challenges for clinical translation.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Humans; Neoplasms; Resveratrol; Stilbenes; Translational Research, Biomedical | 2015 |
Preventive and therapeutic role of traditional Chinese herbal medicine in hepatocellular carcinoma.
Topics: Abietanes; Benzylisoquinolines; Berberine; Carcinoma, Hepatocellular; Curcumin; Drugs, Chinese Herbal; Humans; Liver Neoplasms; Medicine, Chinese Traditional; Resveratrol; Scutellaria baicalensis; Stilbenes | 2015 |
The impact of moderate wine consumption on health.
Topics: Antioxidants; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes; Vitis; Wine | 2015 |
Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases.
Topics: Animals; Blood Pressure; Cardiovascular Agents; Cardiovascular Diseases; Clinical Trials as Topic; Heart Rate; Humans; Resveratrol; Stilbenes; Vasodilation | 2015 |
Anti-inflammatory and antifibrotic effects of resveratrol in the lung.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Disease Models, Animal; Fibrosis; Humans; Inflammation; Liver Diseases; Lung; Mice; Pulmonary Disease, Chronic Obstructive; Resveratrol; Stilbenes | 2015 |
Resveratrol as a therapeutic agent for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Neuroprotective Agents; Oxidative Stress; Resveratrol; Stilbenes | 2014 |
Metabolic effects of resveratrol: addressing the controversies.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cyclic Nucleotide Phosphodiesterases, Type 4; Diabetes Mellitus, Type 2; Humans; Longevity; Neuroprotective Agents; Obesity; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Tardive dyskinesia (syndrome): Current concept and modern approaches to its management.
Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; alpha-Tocopherol; Amantadine; Anticonvulsants; Antioxidants; Antipsychotic Agents; Clonazepam; Dopamine Agents; Drugs, Chinese Herbal; Fatty Acids, Omega-3; Ginkgo biloba; Humans; Isoleucine; Isoxazoles; Leucine; Levetiracetam; Melatonin; Movement Disorders; Nootropic Agents; Piracetam; Plant Extracts; Propranolol; Pyridoxine; Resveratrol; Stilbenes; Tetrabenazine; Valine; Vitamins; Zonisamide | 2015 |
Resveratrol nanoformulations: challenges and opportunities.
Topics: Animals; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Humans; Nanoparticles; Nanotechnology; Resveratrol; Solubility; Stilbenes | 2015 |
Resveratrol and inflammation: Challenges in translating pre-clinical findings to improved patient outcomes.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Inflammation; Obesity; Resveratrol; Stilbenes; Translational Research, Biomedical | 2015 |
[The use of various diet supplements in metabolic syndrome].
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Calcium; Caloric Restriction; Diabetes Mellitus, Type 2; Dietary Supplements; Fatty Acids, Omega-3; Garlic; Humans; Magnesium; Metabolic Syndrome; Obesity; Panax; Photinia; Phytotherapy; Plant Preparations; Resveratrol; Risk Reduction Behavior; Selenium; Stilbenes; Tea; Zinc | 2015 |
Common pathways in health benefit properties of RSV in cardiovascular diseases, cancers and degenerative pathologies.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Humans; Neoplasms; Neurodegenerative Diseases; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Wine | 2015 |
The role of dietary polyphenols in the management of inflammatory bowel disease.
Topics: Animals; Curcumin; Disease Management; Fruit; Humans; Inflammatory Bowel Diseases; Oxidative Stress; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Tea | 2015 |
Suitability of Different Food Grade Materials for the Encapsulation of Some Functional Foods Well Reported for Their Advantages and Susceptibility.
Topics: Carotenoids; Dietary Supplements; Fatty Acids; Flavonoids; Food Technology; Fruit; Functional Food; Humans; Oligosaccharides; Plant Proteins; Polysaccharides; Resveratrol; Stilbenes; Technology, Pharmaceutical; Vegetables | 2016 |
Modulation of SIRT1-Foxo1 signaling axis by resveratrol: implications in skeletal muscle aging and insulin resistance.
Topics: Animals; Cellular Senescence; Forkhead Transcription Factors; Humans; Insulin Resistance; Muscle, Skeletal; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Resveratrol supplementation: Where are we now and where should we go?
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; Dietary Supplements; Exercise; Humans; Resveratrol; Stilbenes | 2015 |
Lifespan and healthspan extension by resveratrol.
Topics: Animals; Drug Design; Humans; Longevity; Resveratrol; Stilbenes | 2015 |
The pharmacology of resveratrol in animals and humans.
Topics: Animals; Clinical Trials as Topic; Humans; Periodicals as Topic; Resveratrol; Stilbenes | 2015 |
Resveratrol, tryptophanum, glycine and vitamin E: a nutraceutical approach to sleep disturbance and irritability in peri- and post-menopause.
Topics: Animals; Dietary Supplements; Female; Functional Food; Glycine; Humans; Mood Disorders; Perimenopause; Postmenopause; Resveratrol; Sleep Wake Disorders; Stilbenes; Tryptophan; Vitamin E | 2015 |
Resveratrol Protects from Toxin-Induced Parkinsonism: Plethora of Proofs Hitherto Petty Translational Value.
Topics: Animals; Humans; Inflammation; Neuroprotective Agents; Neurotoxins; Parkinsonian Disorders; Resveratrol; Stilbenes; Translational Research, Biomedical | 2016 |
Dietary phenolics against colorectal cancer--From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs.
Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Diet; Drug Screening Assays, Antitumor; Gastrointestinal Microbiome; Humans; Lythraceae; Phenols; Resveratrol; Stilbenes; Tea; Zingiber officinale | 2015 |
The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: a review.
Topics: Chromatin; Diet; DNA Methylation; Epigenesis, Genetic; Flavonoids; Genome, Human; Genomic Instability; Histone Acetyltransferases; Histone Deacetylases; Histones; Humans; Indoles; Protein Processing, Post-Translational; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol Targets in Inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Inflammation Mediators; Resveratrol; Stilbenes | 2015 |
A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer.
Topics: Animals; Catechin; Cell Proliferation; Cucurbitacins; Curcumin; Disease Models, Animal; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Neoplasms; Phytochemicals; Resveratrol; Signal Transduction; STAT Transcription Factors; Stilbenes | 2015 |
Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses.
Topics: Amino Acids; Beta vulgaris; Blood Pressure; Carotenoids; Clinical Trials as Topic; Dietary Supplements; Fatty Acids, Unsaturated; Flavonoids; Fruit and Vegetable Juices; Garlic; Humans; Hypertension; Lycopene; Magnesium; Melatonin; Meta-Analysis as Topic; Minerals; Peptides; Plant Extracts; Potassium; Probiotics; Proteins; Resveratrol; Stilbenes; Ubiquinone; Vitamins | 2015 |
Anti-tumor effects and cellular mechanisms of resveratrol.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Epithelial-Mesenchymal Transition; Humans; Matrix Metalloproteinase 9; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Impact of Dietary Antioxidants on Sport Performance: A Review.
Topics: Acetylcysteine; Antioxidants; Athletic Performance; Beta vulgaris; Beverages; Dietary Supplements; Humans; Quercetin; Resveratrol; Spirulina; Stilbenes; Vitamin E | 2015 |
Myocardial metabolism in diabetic cardiomyopathy: potential therapeutic targets.
Topics: Animals; Antioxidants; Diabetes Mellitus; Diabetic Cardiomyopathies; Humans; Mitochondria; Myocardium; Resveratrol; Stilbenes | 2015 |
Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases.
Topics: Animals; Antioxidants; Caloric Restriction; Humans; Inflammation; Longevity; Melatonin; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Chemistry and Biology of Resveratrol-Derived Natural Products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Benzofurans; Biological Products; Models, Chemical; Resveratrol; Stilbenes | 2015 |
Wine, alcohol and pills: What future for the French paradox?
Topics: Alcohol Drinking; Animals; Biological Availability; Cardiovascular Diseases; France; Humans; Polyphenols; Resveratrol; Stilbenes; Wine | 2015 |
Lack of efficacy of resveratrol on C-reactive protein and selected cardiovascular risk factors--Results from a systematic review and meta-analysis of randomized controlled trials.
Topics: Antioxidants; C-Reactive Protein; Cardiotonic Agents; Cardiovascular Diseases; Female; Humans; Male; Prognosis; Randomized Controlled Trials as Topic; Resveratrol; Risk Assessment; Severity of Illness Index; Stilbenes; Survival Rate; Treatment Outcome | 2015 |
Application of resveratrol in diabetes: rationale, strategies and challenges.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antioxidants; Carbohydrate Metabolism; Cardiotonic Agents; Diabetes Mellitus; Enzyme Activation; Glucose Transporter Type 4; Humans; Hypoglycemic Agents; Insulin Resistance; Mice; Oxidative Stress; Rats; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Regulation of redox signalling and autophagy during cardiovascular diseases-role of resveratrol.
Topics: Animals; Antioxidants; Autophagy; Cardiovascular Diseases; Humans; Oxidation-Reduction; Resveratrol; Stilbenes | 2015 |
Metabolomics of cancer cell cultures to assess the effects of dietary phytochemicals.
Topics: Cell Line, Tumor; Curcumin; Humans; Magnetic Resonance Spectroscopy; Metabolome; Metabolomics; Neoplasms; Phytochemicals; Resveratrol; Stilbenes | 2017 |
Anticarcinogenic Effects of Dietary Phytoestrogens and Their Chemopreventive Mechanisms.
Topics: Antioxidants; Chemoprevention; Genistein; Humans; Isoflavones; Phytoestrogens; Resveratrol; Stilbenes | 2015 |
Dual effect of red wine on liver redox status: a concise and mechanistic review.
Topics: Alcohol Drinking; Animals; Antioxidants; Humans; Liver; Liver Diseases, Alcoholic; Oxidation-Reduction; Oxidative Stress; Polyphenols; Resveratrol; Stilbenes; Wine | 2015 |
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerative Diseases; Resveratrol; Sirolimus; Spermidine; Stilbenes; Sulfoxides; Trehalose; Valproic Acid | 2015 |
Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cell Cycle; Humans; Molecular Targeted Therapy; Protein Processing, Post-Translational; Resveratrol; Stilbenes | 2015 |
Resveratrol, in its natural combination in whole grape, for health promotion and disease management.
Topics: Animals; Cardiovascular Diseases; Clinical Trials as Topic; Diet; Disease Management; Fruit; Humans; Metabolic Diseases; Resveratrol; Stilbenes; Vitis | 2015 |
Resveratrol nanoformulation for cancer prevention and therapy.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Humans; Nanocapsules; Neoplasms; Resveratrol; Stilbenes | 2015 |
The effects of resveratrol and SIRT1 activation on dystrophic cardiomyopathy.
Topics: Animals; Cardiomyopathies; Cardiotonic Agents; E1A-Associated p300 Protein; Enzyme Activation; Humans; Muscular Dystrophy, Duchenne; Proteolysis; Resveratrol; Sirtuin 1; Stilbenes; Ubiquitination | 2015 |
SIRT1 as a Promising Novel Therapeutic Target for Myocardial Ischemia Reperfusion Injury and Cardiometabolic Disease.
Topics: Animals; Apoptosis; Disease Models, Animal; Heterocyclic Compounds, 4 or More Rings; Humans; Metabolic Diseases; Molecular Targeted Therapy; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Resveratrol; Sirtuin 1; Stilbenes; Transcriptional Activation | 2017 |
Antioxidants in Translational Medicine.
Topics: Animals; Antioxidants; Humans; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Translational Research, Biomedical | 2015 |
Organ-Protective Effects of Red Wine Extract, Resveratrol, in Oxidative Stress-Mediated Reperfusion Injury.
Topics: Animals; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Signal Transduction; Stilbenes; Wine | 2015 |
Resveratrol, a polyphenol phytoalexin, protects against doxorubicin-induced cardiotoxicity.
Topics: Animals; Cardiotonic Agents; Cardiotoxicity; Doxorubicin; Humans; Myocytes, Cardiac; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes | 2015 |
Resveratrol: A Focus on Several Neurodegenerative Diseases.
Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Humans; Huntington Disease; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Parkinson Disease; Resveratrol; Stilbenes | 2015 |
An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cardiovascular Diseases; Central Nervous System; Humans; Kidney Diseases; Metabolic Diseases; Neuroprotective Agents; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Exploring new ways of regulation by resveratrol involving miRNAs, with emphasis on inflammation.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Gene Expression; Humans; Immunity, Innate; Inflammation; Inflammation Mediators; Lipid Metabolism; MicroRNAs; Resveratrol; RNA Interference; Stilbenes | 2015 |
Evaluating resveratrol as a therapeutic bone agent: preclinical evidence from rat models of osteoporosis.
Topics: Animals; Bone Density Conservation Agents; Dietary Supplements; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Osteoporosis; Rats; Resveratrol; Stilbenes | 2015 |
Resveratrol as a novel treatment for diseases with mTOR pathway hyperactivation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Humans; Molecular Targeted Therapy; Neoplasms; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2015 |
Therapeutic potential of resveratrol in heart failure.
Topics: Animals; Cardiotonic Agents; Heart Failure; Humans; Resveratrol; Stilbenes | 2015 |
Resveratrol and derivatives for the treatment of atrial fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiotonic Agents; Humans; Resveratrol; Stilbenes | 2015 |
Effects of pterostilbene and resveratrol on brain and behavior.
Topics: Aging; Animals; Antioxidants; Blood-Brain Barrier; Brain; Cognition Disorders; Humans; Neurodegenerative Diseases; Resveratrol; Social Behavior Disorders; Stilbenes; Treatment Outcome | 2015 |
Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans.
Topics: Aging; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Biological Availability; Humans; Models, Animal; Oxidoreductases; Resveratrol; Sirtuins; Stilbenes | 2015 |
An overview of the efficacy of resveratrol in the management of ischemic heart disease.
Topics: Animals; Cardiotonic Agents; Coronary Artery Disease; Genetic Therapy; Humans; Myocardial Reperfusion Injury; Resveratrol; Stilbenes | 2015 |
Resveratrol metabolite profiling in clinical nutrition research--from diet to uncovering disease risk biomarkers: epidemiological evidence.
Topics: Animals; Biomarkers; Cardiotonic Agents; Cardiovascular Diseases; Diet; Humans; Nutrition Assessment; Resveratrol; Stilbenes | 2015 |
Anti-Inflammatory and Organ-Protective Effects of Resveratrol in Trauma-Hemorrhagic Injury.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Humans; Resveratrol; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Wounds and Injuries | 2015 |
Resveratrol neuroprotection in stroke and traumatic CNS injury.
Topics: Animals; Antioxidants; Brain Injuries; Humans; Neuroprotection; Neuroprotective Agents; Resveratrol; Stilbenes; Stroke | 2015 |
Resveratrol in the treatment of pancreatic cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Humans; Pancreatic Neoplasms; Resveratrol; Stilbenes | 2015 |
Over-the-counter anti-oxidant therapies for use in multiple sclerosis: A systematic review.
Topics: Animals; Antioxidants; Catechin; Ginkgo biloba; Humans; Multiple Sclerosis; Nonprescription Drugs; Quercetin; Resveratrol; Stilbenes; Thioctic Acid | 2015 |
Resveratrol and anti-atherogenic effects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Humans; Resveratrol; Stilbenes | 2015 |
Ovarian actions of resveratrol.
Topics: Animals; Clinical Trials as Topic; Female; Humans; Ovarian Diseases; Ovary; Resveratrol; Stilbenes | 2015 |
Assessing the aftermath of an alcohol-fueled weekend: Alcohol-induced DNA damage and faulty repairs may raise the risk of certain cancers, but resveratrol could provide some relief.
Topics: Alcohol-Related Disorders; Anticarcinogenic Agents; Binge Drinking; DNA Damage; Female; Humans; Male; Neoplasms; Prognosis; Resveratrol; Risk Assessment; Stilbenes; Treatment Outcome | 2015 |
Properties and molecular mechanisms of resveratrol: a review.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Cycle; Gene Expression Regulation, Neoplastic; Humans; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Reviewing the Role of Resveratrol as a Natural Modulator of Microglial Activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammation; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Stilbenes | 2015 |
Exercise Pills: At the Starting Line.
Topics: Acetylcarnitine; Animals; Biomimetic Materials; Catechin; Exercise; Fibronectins; Humans; Molecular Targeted Therapy; Pyrrolidines; Resveratrol; Stilbenes; Thiazoles; Thiophenes | 2015 |
Resveratrol: A potential challenger against gastric cancer.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle; Cell Proliferation; Cellular Senescence; Diet; Disease Progression; Epigenesis, Genetic; Helicobacter pylori; Humans; Life Style; Mice; Mice, Nude; Neoplasm Transplantation; Polyphenols; Quality of Life; Resveratrol; Signal Transduction; Stilbenes; Stomach Neoplasms | 2015 |
Resveratrol, sirtuins, and viruses.
Topics: Animals; Antiviral Agents; Biological Products; Humans; Resveratrol; Sirtuins; Stilbenes; Viruses | 2015 |
Nutrients and ageing: what can we learn about ageing interactions from animal biology?
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Diet; Humans; Longevity; Mole Rats; Oxidative Stress; Resveratrol; Stilbenes | 2016 |
Phytochemical Compounds and Protection from Cardiovascular Diseases: A State of the Art.
Topics: Animals; Cardiovascular Diseases; Humans; Mice; Phytochemicals; Plant Extracts; Protective Agents; Resveratrol; Stilbenes | 2015 |
The role and potential mechanism of resveratrol in the prevention and control of epilepsy.
Topics: Animals; Anticonvulsants; Epilepsy; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2015 |
Enhancing Activity of Anticancer Drugs in Multidrug Resistant Tumors by Modulating P-Glycoprotein through Dietary Nutraceuticals.
Topics: Abietanes; Alkaloids; Allyl Compounds; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Benzodioxoles; beta Carotene; Biflavonoids; Capsaicin; Catechin; Catechols; Curcumin; Dietary Supplements; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fatty Alcohols; Furocoumarins; Humans; Indoles; Limonins; Neoplasms; Phytotherapy; Piperidines; Polyunsaturated Alkamides; Proanthocyanidins; Quercetin; Resveratrol; Stilbenes; Sulfides; Tea; Triterpenes; Xanthophylls | 2015 |
Natural polyphenols based new therapeutic avenues for advanced biomedical applications.
Topics: Aging; Animals; Anti-Infective Agents; Antioxidants; Catechin; Food Hypersensitivity; Humans; Models, Biological; Neoplasms; Polyphenols; Renal Insufficiency; Resveratrol; Stilbenes; Stroke | 2015 |
Novel promising therapeutics against chronic neuroinflammation and neurodegeneration in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Biological Products; Chronic Disease; Curcumin; Fish Oils; Humans; Inflammation; Neurodegenerative Diseases; Neurofibrillary Tangles; Neuroprotective Agents; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2016 |
[Pharmacological therapy of age-related macular degeneration based on etiopathogenesis].
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Aspirin; Bosentan; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Folic Acid; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infliximab; Lutein; Macular Degeneration; Melatonin; PPAR gamma; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Resveratrol; Stilbenes; Sulfonamides; Trimetazidine; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin D; Xanthophylls | 2015 |
Experimental evidence of pharmacological management of anchorage in Orthodontics: A systematic review.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antioxidants; Bone Remodeling; Celecoxib; Clodronic Acid; Diclofenac; Diphosphonates; Humans; Imidazoles; Interferon-gamma; Isoxazoles; Lactones; Mice; Orthodontic Anchorage Procedures; Osteoclasts; Osteoprotegerin; Pamidronate; Rats; Resveratrol; Stilbenes; Sulfones; Tooth Mobility; Tooth Movement Techniques; Zoledronic Acid | 2015 |
Critical review of resveratrol in xenobiotic-induced hepatotoxicity.
Topics: Antioxidants; Chemical and Drug Induced Liver Injury; Humans; Liver Failure, Acute; Resveratrol; Stilbenes; Xenobiotics | 2015 |
Natural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic Infection.
Topics: Biological Products; Chronic Disease; Curcumin; Hepatitis C; HIV Infections; Humans; Immunity, Cellular; Immunologic Factors; Inflammation; Resveratrol; Silymarin; Stilbenes | 2015 |
Inhibition of IAPP Aggregation and Toxicity by Natural Products and Derivatives.
Topics: Catechin; Curcumin; Diabetes Mellitus, Type 2; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Resveratrol; Stilbenes | 2016 |
Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biological Products; Cancer Vaccines; Chemoprevention; Cytarabine; Dietary Supplements; Humans; Neoplasms; Phytochemicals; Resveratrol; Stilbenes | 2016 |
Beneficial action of resveratrol: How and why?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Autistic Disorder; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Cytochrome P-450 CYP1A1; Diabetes Mellitus, Type 2; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-17; Lipoxins; Metabolic Syndrome; NF-kappa B; Resveratrol; Stilbenes; Transcription Factors; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2016 |
A Comprehensive Review on the Chemotherapeutic Potential of Piceatannol for Cancer Treatment, with Mechanistic Insights.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Neoplasms; Resveratrol; Stilbenes | 2016 |
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Humans; Metformin; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Thiazolidinediones; Wound Healing | 2016 |
Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Molecular Targeted Therapy; Plant Extracts; Resveratrol; Stilbenes | 2016 |
Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules.
Topics: Adipocytes; Adipogenesis; Adiponectin; Adipose Tissue; Animals; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Fatty Acid Synthase, Type I; Fatty Acid-Binding Proteins; Gene Expression Regulation; Genistein; Humans; Hydroxycholesterols; Mice; Obesity; PPAR gamma; Protein Isoforms; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Role of Natural Stilbenes in the Prevention of Cancer.
Topics: Animals; Chemoprevention; Clinical Trials as Topic; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
Resveratrol and the mitochondria: From triggering the intrinsic apoptotic pathway to inducing mitochondrial biogenesis, a mechanistic view.
Topics: Animals; Apoptosis; Humans; Mitochondria; Neoplasms; Neurodegenerative Diseases; Resveratrol; Stilbenes | 2016 |
Cadmium Protection Strategies--A Hidden Trade-Off?
Topics: Animals; Antioxidants; Cadmium; Cell Line; Chelating Agents; Endoplasmic Reticulum Stress; Environmental Pollutants; Fibroblasts; Flavonoids; Glutathione; Humans; Inactivation, Metabolic; Metallothionein; Mitochondria; Mitophagy; Oxidative Stress; Resveratrol; Stilbenes; Zebrafish | 2016 |
Pharmacological activities and structure-modification of resveratrol analogues.
Topics: Animals; Antioxidants; Benzene Derivatives; Heterocyclic Compounds; Humans; Resveratrol; Stilbenes; Structure-Activity Relationship | 2015 |
Combination chemoprevention with grape antioxidants.
Topics: Animals; Anthocyanins; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Catechin; Cell Line, Tumor; Chemoprevention; Disease Models, Animal; Humans; Kaempferols; Neoplasms; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Vitis | 2016 |
Modulation of leptin resistance by food compounds.
Topics: Agouti-Related Protein; Animals; Blood-Brain Barrier; Caffeine; Eating; Food; Hypothalamus; Leptin; Low Density Lipoprotein Receptor-Related Protein-2; Neurons; Neuropeptide Y; Obesity; Pentacyclic Triterpenes; Pro-Opiomelanocortin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptors, Leptin; Resveratrol; Saponins; Stilbenes; Taurine; Triterpenes | 2016 |
Resveratrol as a Potential Therapeutic Candidate for the Treatment and Management of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2016 |
Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?
Topics: Animals; Anticarcinogenic Agents; Area Under Curve; Brassica; Chemoprevention; Curcumin; Disease Models, Animal; Exercise; Gene Expression Profiling; Glucosinolates; Glycoside Hydrolases; Humans; Isothiocyanates; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Nitriles; Nutrigenomics; Nutritional Sciences; Oxidation-Reduction; Phytochemicals; Resveratrol; Signal Transduction; Silymarin; Stilbenes; Sulfoxides | 2016 |
Impact of nanotechnology on the delivery of natural products for cancer prevention and therapy.
Topics: Animals; Anticarcinogenic Agents; Biological Products; Catechin; Cell Line, Tumor; Chemoprevention; Curcumin; Disease Models, Animal; Humans; Nanoparticles; Nanotechnology; Neoplasms; Resveratrol; Stilbenes | 2016 |
[The role of resveratrol in the regulation of cell metabolism--a review].
Topics: Caloric Restriction; Humans; Longevity; Resveratrol; Sirtuin 1; Stilbenes; Vitis; Wine; Yeasts | 2016 |
Anti-Oxidant, Anti-Inflammatory and Anti-Angiogenic Properties of Resveratrol in Ocular Diseases.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Eye Diseases; Gene Expression Regulation; Humans; Resveratrol; Stilbenes | 2016 |
[Resveratrol in Pharmaceutical Chemistry].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Blood Glucose; Cardiovascular System; Chemistry, Pharmaceutical; Dietary Supplements; Humans; Hungary; Obesity; Resveratrol; Solubility; Stilbenes | 2015 |
Inhibition of Glycogen Synthase Kinase-3: An Emerging Target in the Treatment of Traumatic Brain Injury.
Topics: Animals; Brain Injuries, Traumatic; Drug Delivery Systems; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Humans; Neuroprotective Agents; Resveratrol; Stilbenes; Treatment Outcome | 2016 |
Resveratrol and Alzheimer's Disease: Mechanistic Insights.
Topics: Alzheimer Disease; Animals; Autophagy; Humans; Mitochondria; Nerve Degeneration; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
Resveratrol and Its Analogs As Antitumoral Agents For Breast Cancer Treatment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Proliferation; Female; Humans; Resveratrol; Stilbenes | 2016 |
Resveratrol Inhibition of Cellular Respiration: New Paradigm for an Old Mechanism.
Topics: Animals; Antioxidants; Cell Respiration; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2016 |
Therapeutic Potential of Resveratrol in Lymphoid Malignancies.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Humans; Lymphoma; Multiple Myeloma; Resveratrol; Stilbenes | 2016 |
[Biological multifunctionality of resveratrol and its derivatives].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antiviral Agents; Cardiotonic Agents; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2015 |
Resveratrol and Ophthalmic Diseases.
Topics: Animals; Dietary Supplements; Eye Diseases; Food Analysis; Humans; Resveratrol; Stilbenes | 2016 |
Antioxidant effects of resveratrol in the cardiovascular system.
Topics: Animals; Antioxidants; Cardiovascular System; Humans; Resveratrol; Stilbenes | 2017 |
Targeting cancer stem-like cells using dietary-derived agents - Where are we now?
Topics: Animals; Anticarcinogenic Agents; Catechin; Cell Line, Tumor; Curcumin; Diet; Disease Models, Animal; Flavonoids; Humans; Isothiocyanates; Neoplasms; Neoplastic Stem Cells; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Sulfoxides; Vitamin A | 2016 |
Effects of exercise training and resveratrol on vascular health in aging.
Topics: Adaptation, Physiological; Aging; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Exercise; Humans; Muscle, Skeletal; Oxidation-Reduction; Resveratrol; Stilbenes; Vascular Stiffness | 2016 |
Wine Resveratrol: From the Ground Up.
Topics: Fruit; Gene Expression Regulation, Plant; Resveratrol; Sirtuins; Stilbenes; Vitis; Wine | 2016 |
Resveratrol and Myopathy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Energy Metabolism; Gene Expression Regulation; Humans; Muscular Diseases; Resveratrol; Stilbenes | 2016 |
Nutritional immunology: function of natural killer cells and their modulation by resveratrol for cancer prevention and treatment.
Topics: Antineoplastic Agents, Phytogenic; Diet; Humans; Killer Cells, Natural; Neoplasms; Nutritional Physiological Phenomena; Plants, Edible; Resveratrol; Stilbenes | 2016 |
Resveratrol and Cardiovascular Diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Dietary Fats; Humans; Resveratrol; Stilbenes; Wine | 2016 |
The Use of Stilbene Scaffold in Medicinal Chemistry and Multi- Target Drug Design.
Topics: Alzheimer Disease; Antineoplastic Agents, Phytogenic; Bibenzyls; Chemistry, Pharmaceutical; Drug Design; Humans; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
The physiological effects of resveratrol and its potential application in high altitude medicine.
Topics: Altitude; Humans; Hypoxia; Polycythemia; Resveratrol; Stilbenes | 2015 |
Roles of Dietary Phytoestrogens on the Regulation of Epithelial-Mesenchymal Transition in Diverse Cancer Metastasis.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Genistein; Humans; Indoles; Kaempferols; Neoplasm Metastasis; Neoplasms; Phytoestrogens; Resveratrol; Stilbenes | 2016 |
In vitro assays in natural products research - a matter of concentration and relevance to in vivo administration using resveratrol, α-mangostin/γ-mangostin and xanthohumol as examples.
Topics: Animals; Biological Products; Dietary Supplements; Flavonoids; Humans; Propiophenones; Resveratrol; Stilbenes; Xanthones | 2017 |
Caloric restriction: beneficial effects on brain aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Biomimetics; Brain; Caloric Restriction; Energy Metabolism; Humans; Resveratrol; Sirolimus; Stilbenes | 2016 |
Energetic interventions for healthspan and resiliency with aging.
Topics: Aging; Caloric Restriction; Diet; Energy Intake; Exercise; Female; Humans; Longevity; Male; Metformin; Resveratrol; Sirolimus; Stilbenes | 2016 |
Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents.
Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Food; Humans; Isothiocyanates; Phytochemicals; Resveratrol; Stilbenes; Sulfoxides | 2016 |
Antireduction: an ancient strategy fit for future.
Topics: Animals; Antioxidants; Catechin; Fumarates; Humans; Oxidants; Oxygen; Resveratrol; Stilbenes | 2016 |
Plant Phenols and Autophagy.
Topics: Animals; Antioxidants; Autophagy; Curcumin; Humans; Phenols; Plant Proteins; Plants; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Challenges in Analyzing the Biological Effects of Resveratrol.
Topics: Alzheimer Disease; Animals; Antioxidants; Biological Availability; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Humans; Metabolic Diseases; Neoplasms; Phytochemicals; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2016 |
Resveratrol: A Potential Hippocampal Plasticity Enhancer.
Topics: Aging; Animals; Disease Models, Animal; Fatigue; Hippocampus; Neurogenesis; Neuronal Plasticity; Resveratrol; Stilbenes; Stress, Physiological; Stroke | 2016 |
Small Molecules as SIRT Modulators.
Topics: Humans; Imidazoles; Naphthalenes; Neoplasms; Neurodegenerative Diseases; Polyphenols; Pyrimidinones; Resveratrol; Sirtuins; Small Molecule Libraries; Stilbenes; Triterpenes | 2018 |
Polyphenol compounds and PKC signaling.
Topics: Curcumin; Humans; Neoplasms; Polyphenols; Protein Kinase C; Resveratrol; Signal Transduction; Stilbenes | 2016 |
The Effects of Resveratrol Supplementation in Overweight and Obese Humans: A Systematic Review of Randomized Trials.
Topics: Anti-Inflammatory Agents; Dietary Supplements; Humans; Obesity; Overweight; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes; Weight Loss | 2016 |
[Effects of resveratrol-induced cellular autophagy in control of neurodegenerative diseases].
Topics: Alzheimer Disease; Autophagy; Humans; Huntington Disease; Neurodegenerative Diseases; Parkinson Disease; Resveratrol; Stilbenes | 2016 |
Strategies for enhancing resveratrol production and the expression of pathway enzymes.
Topics: Anti-Inflammatory Agents; Antioxidants; Cell Culture Techniques; Escherichia coli; Metabolic Engineering; Plant Cells; Plants; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2016 |
Resveratrol: How Much Wine Do You Have to Drink to Stay Healthy?
Topics: Coronary Disease; Diet; Dietary Supplements; Fruit; Glycosides; Humans; Inflammation; Metabolic Diseases; Neurodegenerative Diseases; Phytotherapy; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Wine | 2016 |
The effects of resveratrol intervention on risk markers of cardiovascular health in overweight and obese subjects: a pooled analysis of randomized controlled trials.
Topics: Biomarkers; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Cholesterol; Humans; Insulin Resistance; Meta-Analysis as Topic; Obesity; Overweight; Randomized Controlled Trials as Topic; Reproducibility of Results; Resveratrol; Risk Factors; Stilbenes | 2016 |
Multiplicity of effects and health benefits of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Arachis; Blood Glucose; Fruit; Humans; Hypoglycemic Agents; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 2016 |
Role of phytochemicals in the inhibition of epithelial-mesenchymal transition in cancer metastasis.
Topics: Antineoplastic Agents, Phytogenic; Carotenoids; Epithelial-Mesenchymal Transition; Flavonoids; Gene Expression; Humans; Isoflavones; Neoplasm Metastasis; Phenols; Phytochemicals; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Tea | 2016 |
Slowing ageing by design: the rise of NAD
Topics: Aging; Allosteric Regulation; Animals; Clinical Trials as Topic; Enzyme Activators; Humans; NAD; Resveratrol; Sirtuins; Stilbenes | 2016 |
Efficacy of Resveratrol Supplementation against Non-Alcoholic Fatty Liver Disease: A Meta-Analysis of Placebo-Controlled Clinical Trials.
Topics: Cholesterol; Female; Humans; Lipoproteins; Male; Non-alcoholic Fatty Liver Disease; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2016 |
Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Checkpoints; Colorectal Neoplasms; Curcumin; Humans; Neovascularization, Pathologic; NF-E2-Related Factor 2; Phytochemicals; Resveratrol; Stilbenes | 2016 |
Role of angiogenic factors of herbal origin in regulation of molecular pathways that control tumor angiogenesis.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Artemisinins; Catechin; Cell Proliferation; Curcumin; Humans; Neoplasms; Neovascularization, Pathologic; Plant Extracts; Resveratrol; Stilbenes; Triterpenes | 2016 |
Anticancer Efficacy of Polyphenols and Their Combinations.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Biological Availability; Catechin; Cell Line, Tumor; Cell Proliferation; Curcumin; Disease Models, Animal; Humans; Micronutrients; Neoplasms; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Tea | 2016 |
Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the Clinical Evidence?
Topics: Animals; Clinical Trials as Topic; Cognition Disorders; Curcumin; Female; Humans; Male; Resveratrol; Stilbenes | 2016 |
The effects of resveratrol on aging vessels.
Topics: Aging; Animals; Antioxidants; Arteriosclerosis; Autophagy; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Oxidative Stress; Resveratrol; Stilbenes | 2016 |
Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review.
Topics: Antineoplastic Agents; Catechin; Coumaric Acids; Dietary Supplements; Dioxoles; Drug Synergism; Drug Therapy, Combination; Humans; Lignans; Neoplasms; Resveratrol; Stilbenes; Tocotrienols | 2016 |
Modulatory Mechanism of Nociceptive Neuronal Activity by Dietary Constituent Resveratrol.
Topics: Animals; Dietary Supplements; Inflammation; Nociceptors; Pain Management; Resveratrol; Stilbenes | 2016 |
Resveratrol and Lifespan in Model Organisms.
Topics: Animals; Clinical Trials as Topic; Humans; Longevity; Resveratrol; Stilbenes | 2016 |
Targeting extracellular matrix remodeling in disease: Could resveratrol be a potential candidate?
Topics: Extracellular Matrix; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors | 2017 |
Research Problems Associated with Resveratrol (trans-3, 5, 4'- trihydroxystilbene; RSV) and Various Strategies to Overcome those Problems (Review).
Topics: Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Humans; Resveratrol; Solubility; Stilbenes | 2017 |
Unraveling the Anticancer Effect of Curcumin and Resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Curcumin; Humans; Neoplasms; Resveratrol; Stilbenes | 2016 |
Treatment of cardiovascular pathology with epigenetically active agents: Focus on natural and synthetic inhibitors of DNA methylation and histone deacetylation.
Topics: Animals; Antioxidants; Cardiovascular Diseases; DNA Methylation; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Humans; Resveratrol; Stilbenes | 2017 |
The paradoxical pro- and antiangiogenic actions of resveratrol: therapeutic applications in cancer and diabetes.
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Neoplasms; Resveratrol; Stilbenes | 2016 |
Anti-metastatic potential of resveratrol and its metabolites by the inhibition of epithelial-mesenchymal transition, migration, and invasion of malignant cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Epithelial-Mesenchymal Transition; Fruit; Humans; Neoplasm Invasiveness; Neoplasms; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes | 2016 |
Anti-obesity effects of resveratrol: comparison between animal models and humans.
Topics: Animals; Anti-Obesity Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Obesity; Resveratrol; Stilbenes | 2016 |
Resveratrol as an anti-cancer agent: A review.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Disease Models, Animal; Fruit; Humans; Neoplasms; Phytoalexins; Phytochemicals; Resveratrol; Sesquiterpenes; Stilbenes; Vitis | 2018 |
A focus on resveratrol and ocular problems, especially cataract: From chemistry to medical uses and clinical relevance.
Topics: Animals; Antioxidants; Cataract; Glaucoma; Humans; Lipid Peroxidation; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
In vitro and in vivo experimental hepatotoxic models in liver research: applications to the assessment of potential hepatoprotective drugs.
Topics: Animals; Biomedical Research; Disease Models, Animal; Down-Regulation; Drug Discovery; Galactosamine; Humans; Lipopolysaccharides; Liver Failure, Acute; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Resveratrol regulates gene transcription via activation of stimulus-responsive transcription factors.
Topics: Animals; Humans; Resveratrol; Signal Transduction; Stilbenes; Transcription Factors; Transcription, Genetic; Transcriptional Activation | 2017 |
Sirtuins and nonalcoholic fatty liver disease.
Topics: Animals; Down-Regulation; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Non-alcoholic Fatty Liver Disease; Resveratrol; Sirtuins; Stilbenes | 2016 |
Antidiabetic Effects of Resveratrol: The Way Forward in Its Clinical Utility.
Topics: Animals; Diabetes Mellitus; Humans; Hypoglycemic Agents; Resveratrol; Stilbenes | 2016 |
Alternative treatment methods attenuate the development of NAFLD: A review of resveratrol molecular mechanisms and clinical trials.
Topics: Complementary Therapies; Hepatocytes; Humans; Insulin Resistance; Lipid Metabolism; Liver; Non-alcoholic Fatty Liver Disease; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2017 |
Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Rheumatoid; Biological Availability; Disease Models, Animal; Humans; Resveratrol; Stilbenes | 2017 |
Health-beneficial nutraceuticals-myth or reality?
Topics: Biological Products; Diet; Dietary Supplements; Health; Hormesis; Humans; Polyphenols; Resveratrol; Stilbenes | 2017 |
Walking a Tightrope: A Perspective of Resveratrol Effects on Breast Cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Breast; Breast Neoplasms; Cell Proliferation; Female; Humans; Resveratrol; Stilbenes; Wine | 2018 |
Liver fibrosis and hepatic stellate cells: Etiology, pathological hallmarks and therapeutic targets.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; CD4-Positive T-Lymphocytes; Disease Progression; Fatty Liver, Alcoholic; Hepatic Stellate Cells; Humans; Interleukins; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Liver Cirrhosis; Macrophages; MicroRNAs; Molecular Targeted Therapy; Non-alcoholic Fatty Liver Disease; Resveratrol; Schistosomiasis; Signal Transduction; Stilbenes; T-Lymphocytes, Regulatory; Triterpenes; Ursodeoxycholic Acid; Ursolic Acid; Virus Diseases | 2016 |
Patent Survey of Resveratrol, Taxol, Podophyllotoxin, Withanolides and Their Derivatives Used in Anticancer Therapy.
Topics: Humans; Neoplasms; Paclitaxel; Patents as Topic; Podophyllotoxin; Resveratrol; Stilbenes; Withanolides | 2017 |
Potential benefits of phytochemicals against Alzheimer's disease.
Topics: Alkaloids; Alzheimer Disease; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Galantamine; Ginkgo biloba; Humans; Melissa; Panax; Phytochemicals; Plant Extracts; Resveratrol; Rivastigmine; Salvia officinalis; Stilbenes; Terpenes | 2017 |
Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD).
Topics: Animals; Biological Products; Catechin; Curcumin; Fructose; Humans; Inflammation; Insulin Resistance; Lipogenesis; Mitochondria; Non-alcoholic Fatty Liver Disease; Resveratrol; Stilbenes | 2017 |
Some Important Dietary Polyphenolic Compounds: An Anti-inflammatory and Immunoregulatory Perspective.
Topics: Aldehydes; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Curcumin; Cyclopentane Monoterpenes; Diet; Humans; Neutrophils; Phenols; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2018 |
Targeting miRNAs by polyphenols: Novel therapeutic strategy for cancer.
Topics: Catechin; Curcumin; Gene Expression Regulation, Neoplastic; Genistein; Humans; MicroRNAs; Neoplasms; Polyphenols; Resveratrol; Signal Transduction; Stilbenes | 2017 |
NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension.
Topics: Acetophenones; Animals; Humans; Hypertension, Pulmonary; NADPH Oxidases; Onium Compounds; Resveratrol; Stilbenes | 2017 |
Current evidence for AMPK activation involvement on resveratrol-induced neuroprotection in cerebral ischemia.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Brain; Brain Ischemia; Cell Survival; Energy Metabolism; Mice; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes | 2018 |
An Overview of Stress-Induced Resveratrol Synthesis in Grapes: Perspectives for Resveratrol-Enriched Grape Products.
Topics: Fertilizers; Fruit; Light; Metals; Ozone; Pesticides; Plant Diseases; Resveratrol; Signal Transduction; Stilbenes; Stress, Physiological; Ultrasonics; Ultraviolet Rays; Up-Regulation; Vitis; Wine | 2017 |
Nutrition, metabolism, and targeting aging in nonhuman primates.
Topics: Aging; Animals; Caloric Restriction; Fibroblast Growth Factors; Humans; Longevity; Macaca mulatta; Nutritional Status; Peroxisome Proliferator-Activated Receptors; Research; Resveratrol; Sirolimus; Stilbenes | 2017 |
Cancer chemoprevention - selected molecular mechanisms.
Topics: Anticarcinogenic Agents; Apoptosis; Catechols; Chemoprevention; Curcumin; Fatty Alcohols; Humans; Neoplasms; Neovascularization, Pathologic; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Implications of Resveratrol on Glucose Uptake and Metabolism.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Transport; Carbohydrate Metabolism; Diabetes Mellitus, Type 2; Drug Synergism; Glucose; Homeostasis; Humans; Neoplasms; Polyphenols; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol as MDR reversion molecule in breast cancer: An overview.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; DNA Repair; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Female; Humans; Inactivation, Metabolic; Phytoestrogens; Resveratrol; Stilbenes | 2017 |
Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease: Systematic Review and Meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bias; Biomarkers; Blood Glucose; Cytokines; Humans; Lipids; Non-alcoholic Fatty Liver Disease; Randomized Controlled Trials as Topic; Resveratrol; Severity of Illness Index; Stilbenes | 2017 |
Cardiovascular Protective Effects and Clinical Applications of Resveratrol.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Cardiotonic Agents; Cardiovascular Diseases; Humans; Hypolipidemic Agents; Phenols; Plant Extracts; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2017 |
Seeking new anti-cancer agents from autophagy-regulating natural products.
Topics: Antineoplastic Agents; Autophagy; Biological Products; Camptothecin; Humans; Irinotecan; Molecular Structure; Paclitaxel; Resveratrol; Stilbenes | 2017 |
Chinese Herbal Medicine for the Optimal Management of Polycystic Ovary Syndrome.
Topics: Androgens; Berberine; Drugs, Chinese Herbal; Female; Ginsenosides; Glucosides; Humans; Insulin Resistance; Monoterpenes; Phenanthrenes; Phytotherapy; Polycystic Ovary Syndrome; Resveratrol; Stilbenes; Theca Cells | 2017 |
Dietary factors in rheumatic autoimmune diseases: a recipe for therapy?
Topics: Autoimmune Diseases; Capsaicin; Chocolate; Coffee; Curcumin; Diet; Fatty Acids, Omega-3; Humans; Microbiota; Resveratrol; Rheumatic Diseases; Sodium Chloride; Stilbenes | 2017 |
Polyphenol nanoformulations for cancer therapy: experimental evidence and clinical perspective.
Topics: Antineoplastic Agents; Antioxidants; Biological Availability; Catechin; Curcumin; Drug Delivery Systems; Humans; Nanocomposites; Nanoparticles; Neoplasms; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2017 |
Resveratrol and endometriosis: In vitro and animal studies and underlying mechanisms (Review).
Topics: Animals; Biological Availability; Endometriosis; Female; Humans; Inflammation; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy.
Topics: Animals; Anticarcinogenic Agents; Antioxidant Response Elements; Antioxidants; Curcumin; Cysteine Proteinase Inhibitors; Diabetic Nephropathies; Enzyme Inhibitors; Humans; Isothiocyanates; Leupeptins; Molecular Targeted Therapy; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Rutin; Signal Transduction; Stilbenes; Sulfoxides; Trace Elements; Zinc | 2017 |
Cellular and Molecular Targets of Resveratrol on Lymphoma and Leukemia Cells.
Topics: Anticarcinogenic Agents; Humans; Leukemia; Lymphoma; Resveratrol; Stilbenes | 2017 |
Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.
Topics: Berberine; Cardiovascular Diseases; Curcumin; Gene Expression Regulation; Glycogen Synthase Kinase 3; Humans; Inflammation; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Neurodegenerative Diseases; Osteoarthritis; Phosphatidylinositol 3-Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol, 4' Acetoxy Resveratrol, R-equol, Racemic Equol or S-equol as Cosmeceuticals to Improve Dermal Health.
Topics: Cosmeceuticals; Equol; Estradiol; Gene Expression Regulation; Humans; Molecular Structure; Phytochemicals; Phytoestrogens; Polyphenols; Protein Binding; Receptors, Estrogen; Resveratrol; Skin Physiological Phenomena; Stilbenes | 2017 |
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apigenin; Artemisinins; Drugs, Chinese Herbal; Emodin; Flavanones; Glucuronates; Humans; Medicine, Chinese Traditional; Pancreas; Pancreatitis; Patient Safety; Phytotherapy; Plant Extracts; Pyrazines; Resveratrol; Rheum; Salvia miltiorrhiza; Stilbenes; Sulfates | 2017 |
Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Biomarkers, Tumor; Chemoprevention; Clinical Trials as Topic; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Outcome Assessment, Health Care; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Childhood cancer chemotherapy-induced bone damage: pathobiology and protective effects of resveratrol and other nutraceuticals.
Topics: Antimetabolites, Antineoplastic; Bone Resorption; Cell Differentiation; Child; Dietary Supplements; Humans; Methotrexate; Neoplasms; Protective Agents; Resveratrol; Stilbenes | 2017 |
Resveratrol and pterostilbene as a microRNA-mediated chemopreventive and therapeutic strategy in prostate cancer.
Topics: Antineoplastic Agents, Phytogenic; Chemoprevention; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Prostatic Neoplasms; Resveratrol; Stilbenes | 2017 |
Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue.
Topics: Adipose Tissue; Animals; Endothelium, Vascular; Mice; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes | 2017 |
Nanoparticle formulations to enhance tumor targeting of poorly soluble polyphenols with potential anticancer properties.
Topics: Biological Availability; Curcumin; Drug Compounding; Humans; Nanoparticles; Neoplasms; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2017 |
Resveratrol derivatives as a pharmacological tool.
Topics: Animals; Humans; Mitochondria; Oxidative Stress; Prodrugs; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging.
Topics: Aging; Animals; Antioxidants; Brain; Humans; Oxidative Stress; Polyphenols; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Regulation of stilbene biosynthesis in plants.
Topics: Biosynthetic Pathways; Environment; Gene Expression Regulation, Plant; Plant Proteins; Plants; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Antioxidant dietary approach in treatment of fatty liver: New insights and updates.
Topics: Animals; Anthocyanins; Antioxidants; Carotenoids; Catechin; Coumestrol; Curcumin; Energy Metabolism; Fatty Liver; Glucosinolates; Humans; Imidoesters; Isothiocyanates; Lipogenesis; Mitochondria; Non-alcoholic Fatty Liver Disease; Nutritional Sciences; Oxidative Stress; Oximes; Polyphenols; Quercetin; Resveratrol; Stilbenes; Sulfoxides; Xanthophylls | 2017 |
The Role of Oxidative Stress Modulators in Breast Cancer.
Topics: Animals; Ascorbic Acid; Breast Neoplasms; Carotenoids; Female; Humans; Melatonin; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Tocopherols | 2018 |
Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Mice; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Effects of Resveratrol and Other Polyphenols on the Most Common Brain Age-Related Diseases.
Topics: Age Factors; Animals; Brain; Humans; Molecular Structure; Neurodegenerative Diseases; Polyphenols; Resveratrol; Stilbenes | 2017 |
Protective molecular mechanisms of resveratrol in UVR-induced Skin carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Autophagy; Carcinogenesis; Cell Cycle; Gene Expression; Humans; Resveratrol; Skin Neoplasms; Stilbenes; Ultraviolet Rays | 2018 |
Antiobesity effects of resveratrol: which tissues are involved?
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anti-Obesity Agents; Humans; Liver; Muscle, Skeletal; Obesity; Resveratrol; Stilbenes | 2017 |
Resveratrol for Alzheimer's disease.
Topics: Alzheimer Disease; Blood-Brain Barrier; Double-Blind Method; Humans; Resveratrol; Sirtuins; Stilbenes; Treatment Outcome | 2017 |
Significance of Resveratrol in Clinical Management of Chronic Diseases.
Topics: Aging; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus; Dose-Response Relationship, Drug; Humans; Neoplasms; Obesity; Polyphenols; Resveratrol; Stilbenes | 2017 |
Resveratrol as a Natural Autophagy Regulator for Prevention and Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Autophagy; Brain; Cognition; Humans; Inflammation Mediators; MicroRNAs; Neuroprotective Agents; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol and diabetes: A critical review of clinical studies.
Topics: Animals; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Humans; Hypoglycemic Agents; Resveratrol; Stilbenes | 2017 |
The grapes and wrath: using resveratrol to treat the pathophysiology of hemorrhagic shock.
Topics: Animals; Antioxidants; Disease Models, Animal; Humans; Oxidative Stress; Resuscitation; Resveratrol; Shock, Hemorrhagic; Stilbenes | 2017 |
Therapeutic applications of resveratrol and its derivatives on periodontitis.
Topics: Anti-Inflammatory Agents; Fibroblasts; Glucosides; Humans; Periodontitis; Porphyromonas gingivalis; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol in the foodomics era: 1:25,000.
Topics: Antioxidants; Biological Availability; Food; Humans; Metabolomics; Resveratrol; Stilbenes; Wine | 2017 |
Natural Modulators of Endosomal Toll-Like Receptor-Mediated Psoriatic Skin Inflammation.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Cytokines; Dermatitis; Endosomes; Humans; Imiquimod; Indazoles; Isonicotinic Acids; Mice; Psoriasis; Resveratrol; Signal Transduction; Skin; Stilbenes; Toll-Like Receptor 7; Toll-Like Receptor 8; Toll-Like Receptor 9; Toll-Like Receptors | 2017 |
Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer.
Topics: Adaptive Immunity; Animals; Autoimmune Diseases; Autophagy; Benzylisoquinolines; Cholecalciferol; Humans; Immune System Diseases; Immunity, Innate; Indoles; Infections; Isoquinolines; Lysosomes; Maprotiline; Metformin; Neoplasms; Phenols; Pyrroles; Resveratrol; Sirolimus; Spermidine; Stilbenes; Tetrahydroisoquinolines; Trehalose | 2017 |
A Critical Assessment of the Therapeutic Potential of Resveratrol Supplements for Treating Mitochondrial Disorders.
Topics: Adenosine Triphosphate; Apoptosis; Dietary Supplements; Humans; Mitochondria; Mitochondrial Diseases; Oxidative Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Biological actions and molecular effects of resveratrol, pterostilbene, and 3'-hydroxypterostilbene.
Topics: Apoptosis; Humans; Resveratrol; Stilbenes | 2017 |
Dietary (Poly)phenols, Brown Adipose Tissue Activation, and Energy Expenditure: A Narrative Review.
Topics: Adipose Tissue, Brown; Adrenergic Agonists; Animals; Anti-Obesity Agents; Body Weight; Diet; Disease Models, Animal; Energy Metabolism; Flavonoids; Humans; Obesity; Polyphenols; Resveratrol; Stilbenes; Tea; Thermogenesis; Uncoupling Protein 1 | 2017 |
Antioxidants: Wonder drugs or quackery?
Topics: alpha-Tocopherol; Antioxidants; beta Carotene; Free Radicals; Humans; Nostrums; Quackery; Resveratrol; Stilbenes | 2017 |
Biological Mechanisms by Which Antiproliferative Actions of Resveratrol Are Minimized.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes; Thyroid Hormones; Treatment Failure | 2017 |
Resveratrol and inflammatory bowel disease.
Topics: Anti-Inflammatory Agents; Antioxidants; Humans; Inflammatory Bowel Diseases; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol and cancer treatment: updates.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Progression; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Does phytoestrogen supplementation improve cognition in humans? A systematic review.
Topics: Cognition; Dietary Supplements; Humans; Phytoestrogens; Resveratrol; Stilbenes | 2017 |
Comprehensive review on the antimicrobial potency of the plant polyphenol Resveratrol.
Topics: Animals; Anti-Infective Agents; Drug Synergism; Humans; Models, Biological; Polyphenols; Resveratrol; Stilbenes | 2017 |
Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol: from diet to topical usage.
Topics: Animals; Cardiovascular Diseases; Cosmetics; Humans; Resveratrol; Skin; Stilbenes | 2017 |
Resveratrol and Amyloid-Beta: Mechanistic Insights.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Humans; Neurons; Resveratrol; Stilbenes | 2017 |
A comprehensive review of the health perspectives of resveratrol.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Resveratrol; Stilbenes | 2017 |
Red Wine, Resveratrol and Atrial Fibrillation.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Atrial Fibrillation; Humans; Myocytes, Cardiac; Polyphenols; Resveratrol; Stilbenes; Wine | 2017 |
Epigenetic Regulatory Mechanisms Induced by Resveratrol.
Topics: Acetylation; Animals; Chromatin Assembly and Disassembly; DNA Methylation; DNA Modification Methylases; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histone Demethylases; Histones; Humans; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Therapeutic Versatility of Resveratrol Derivatives.
Topics: Antineoplastic Agents; Antioxidants; Cardiovascular Agents; Humans; Molecular Structure; Neuroprotective Agents; Resveratrol; Stilbenes | 2017 |
Effects of Resveratrol against Lung Cancer: In Vitro and In Vivo Studies.
Topics: Cell Line, Tumor; Cell Survival; Humans; Lung Neoplasms; Resveratrol; Stilbenes | 2017 |
The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity.
Topics: Animals; Antioxidants; Curcumin; Disease Models, Animal; Humans; Mice; Obesity; Quercetin; Rats; Resveratrol; Stilbenes | 2017 |
Cardiovascular and Antiobesity Effects of Resveratrol Mediated through the Gut Microbiota.
Topics: Animals; Anti-Obesity Agents; Cardiovascular Diseases; Diet, High-Fat; Energy Metabolism; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Obesity; Resveratrol; Stilbenes | 2017 |
Resveratrol, pterostilbene, and dementia.
Topics: Alzheimer Disease; Animals; Antioxidants; Biological Transport; Blood-Brain Barrier; Brain; Clinical Trials as Topic; Cognitive Dysfunction; Dementia; Disease Models, Animal; Humans; Maze Learning; Neuroprotective Agents; Resveratrol; Stilbenes | 2018 |
Resveratrol-Induced Effects on Body Fat Differ Depending on Feeding Conditions.
Topics: Adipose Tissue; Animals; Body Weight; Clinical Trials as Topic; Diet; Drug Evaluation, Preclinical; Energy Metabolism; Humans; Obesity; Resveratrol; Stilbenes | 2017 |
Anti-Aging Drugs - Prospect of Longer Life?
Topics: Animals; Humans; Longevity; Metformin; NAD; Quality of Life; Resveratrol; Sirolimus; Stilbenes | 2018 |
Role of resveratrol in regulation of cellular defense systems against oxidative stress.
Topics: Animals; Antioxidants; Catalase; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; NF-E2 Transcription Factor; NF-kappa B; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2018 |
Resveratrol Role in Autoimmune Disease-A Mini-Review.
Topics: Animals; Autoimmune Diseases; Humans; Molecular Structure; Resveratrol; Stilbenes | 2017 |
The Role of Resveratrol in Cancer Therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Neoplasms; Resveratrol; Stilbenes | 2017 |
Dietary Polyphenols in the Prevention of Stroke.
Topics: Animals; Diet; Humans; Nitric Oxide; Oxidative Stress; Oxidoreductases; Polyphenols; Protective Agents; Quercetin; Resveratrol; Stilbenes; Stroke | 2017 |
Targeting cancer stem cells and signaling pathways by resveratrol and pterostilbene.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Carcinogenesis; Cell Communication; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Proteins; Neoplastic Stem Cells; Resveratrol; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2018 |
Resveratrol, human health and winemaking perspectives.
Topics: Diet; Dietary Supplements; Humans; Oxidative Stress; Plant Diseases; Polyphenols; Resveratrol; Stilbenes; Vitis; Wine | 2019 |
Effect of resveratrol and pterostilbene on aging and longevity.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cardiovascular Diseases; Cataract; Cellular Senescence; Humans; Inflammation; Longevity; Neoplasms; Neurodegenerative Diseases; NF-E2-Related Factor 2; Osteoporosis; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Telomere Homeostasis | 2018 |
Chemoprevention by resveratrol and pterostilbene: Targeting on epigenetic regulation.
Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Bone Diseases; Cardiovascular Diseases; Chemoprevention; DNA Methylation; Epigenesis, Genetic; Histones; Humans; MicroRNAs; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Resveratrol; Stilbenes | 2018 |
Resveratrol as a potential therapeutic drug for respiratory system diseases.
Topics: Animals; Humans; Respiration Disorders; Resveratrol; Stilbenes | 2017 |
Beneficial Properties of Phytochemicals on NLRP3 Inflammasome-Mediated Gout and Complication.
Topics: Animals; Antioxidants; Crystallization; Diet; Flavonoids; Gout; Humans; Inflammasomes; Interleukin-1beta; NLR Family, Pyrin Domain-Containing 3 Protein; Phytochemicals; Phytotherapy; Resveratrol; Stilbenes; Uric Acid | 2018 |
Metabolism and pharmacokinetics of resveratrol and pterostilbene.
Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Clinical Trials as Topic; Glucuronosyltransferase; Half-Life; Humans; Injections, Intravenous; Mice; Rats; Resveratrol; Solubility; Stilbenes | 2018 |
Antiobesity molecular mechanisms of action: Resveratrol and pterostilbene.
Topics: Adipocytes; Adipokines; Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anti-Obesity Agents; Diet, High-Fat; Energy Metabolism; Gastrointestinal Microbiome; Gene Expression; Humans; Obesity; Resveratrol; Signal Transduction; Stilbenes; Thermogenesis | 2018 |
Oral delivery system enhanced the bioavailability of stilbenes: Resveratrol and pterostilbene.
Topics: Administration, Oral; Animals; Biological Availability; Drug Delivery Systems; Emulsions; Half-Life; Humans; Liposomes; Nanoparticles; Rats; Resveratrol; Solubility; Stilbenes; Swine | 2018 |
Novel insights into the pharmacological effects of resveratrol on the management of depression: a short review.
Topics: Animals; Antidepressive Agents; Cytokines; Depression; Disease Progression; Humans; Hypothalamo-Hypophyseal System; Oxidative Stress; Pituitary-Adrenal System; Resveratrol; Stilbenes | 2017 |
Regulation of Cell Signaling Pathways and miRNAs by Resveratrol in Different Cancers.
Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; MicroRNAs; Neoplasms; Receptors, Notch; Resveratrol; Signal Transduction; Smad Proteins; STAT Transcription Factors; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Transforming Growth Factor beta1; Treatment Outcome; Wnt Signaling Pathway; Zinc Finger Protein GLI1 | 2018 |
Potential of resveratrol in mitigating metabolic disturbances induced by ethanol.
Topics: Animals; Antioxidants; Ethanol; Humans; Lipid Metabolism; Liver; Liver Diseases; Metabolic Diseases; Resveratrol; Stilbenes | 2018 |
Biological Activities of Stilbenoids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cardiotonic Agents; Cell Line, Tumor; Humans; Hypoglycemic Agents; Models, Animal; Neuroprotective Agents; Resveratrol; Stilbenes | 2018 |
Curcumin and dietary polyphenol research: beyond drug discovery.
Topics: Animals; Anthocyanins; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Cell Line; Curcumin; Drug Discovery; Fibroblast Growth Factors; Humans; Insulin; Insulin Resistance; Nuclear Proteins; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Transcription Factors | 2018 |
An Interplay between Senescence, Apoptosis and Autophagy in Glioblastoma Multiforme-Role in Pathogenesis and Therapeutic Perspective.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Autophagy; Brain Neoplasms; Cellular Senescence; Dacarbazine; Disease Models, Animal; DNA Damage; Glioblastoma; Humans; Mice; Resveratrol; Stilbenes; Temozolomide | 2018 |
Dendrimers for Drug Delivery.
Topics: Dendrimers; Drug Delivery Systems; Drug Liberation; Indomethacin; Resveratrol; Stilbenes | 2018 |
Cerebral Blood Flow Measurements in Adults: A Review on the Effects of Dietary Factors and Exercise.
Topics: Alcohol Drinking; Brain; Caffeine; Cerebrovascular Circulation; Cognition; Cognitive Aging; Diet; Dietary Supplements; Exercise; Fatty Acids, Omega-3; Humans; Resveratrol; Stilbenes | 2018 |
[Progress in regulation of drug transporters and metabolic enzymes by resveratrol].
Topics: Animals; Biological Transport; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Membrane Transport Proteins; Resveratrol; Stilbenes | 2016 |
Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Inflammation; Mice; Neoplasms; Obesity; Rats; Respiratory Tract Diseases; Resveratrol; Stilbenes | 2018 |
Multi-effects of Resveratrol on stem cell characteristics: Effective dose, time, cell culture conditions and cell type-specific responses of stem cells to Resveratrol.
Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Resveratrol; Stem Cell Transplantation; Stem Cells; Stilbenes; Structure-Activity Relationship | 2018 |
Resveratrol Boosts Cognitive Function by Targeting SIRT1.
Topics: Animals; Apoptosis; Autophagy; Cognition; Cognitive Dysfunction; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Resveratrol: An overview of its anti-cancer mechanisms.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Autophagy; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Female; Humans; Inflammasomes; Male; Mice; Neoplasm Metastasis; NF-E2-Related Factor 2; Phytoalexins; Rats; Resveratrol; Sesquiterpenes; Skin Neoplasms; Stilbenes | 2018 |
Heterologous production of resveratrol in bacterial hosts: current status and perspectives.
Topics: Bacteria; Bacterial Proteins; Biosynthetic Pathways; Biotechnology; Gene Expression Regulation, Bacterial; Genetic Engineering; Industrial Microbiology; Malonyl Coenzyme A; Metabolic Engineering; Microorganisms, Genetically-Modified; Resveratrol; Stilbenes | 2018 |
Protective effects of Vitis vinifera (grapes) and one of its biologically active constituents, resveratrol, against natural and chemical toxicities: A comprehensive review.
Topics: Animals; Antioxidants; Fruit; Humans; Phenols; Plant Extracts; Protective Agents; Resveratrol; Stilbenes; Vitis | 2018 |
Prevention from radiation damage by natural products.
Topics: Antioxidants; Ascorbic Acid; Curcumin; DNA Damage; Flavonoids; Humans; Lipid Peroxidation; Neoplasms; Phytochemicals; Plants; Polyphenols; Radiation Injuries; Radiation-Protective Agents; Radiotherapy; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
Resveratrol as a Novel Anti-Herpes Simplex Virus Nutraceutical Agent: An Overview.
Topics: Animals; Antiviral Agents; Dietary Supplements; Disease Models, Animal; Herpes Simplex; Humans; Resveratrol; Simplexvirus; Stilbenes; Treatment Outcome | 2018 |
Biosynthesis of resveratrol and piceatannol in engineered microbial strains: achievements and perspectives.
Topics: Biosynthetic Pathways; Corynebacterium glutamicum; Escherichia coli; Metabolic Engineering; Microorganisms, Genetically-Modified; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Synthetic Biology | 2019 |
Hybrid
Topics: Antineoplastic Agents, Phytogenic; Chemistry, Pharmaceutical; Coumarins; Curcumin; Humans; Oleanolic Acid; Resveratrol; Stilbenes; Structure-Activity Relationship | 2019 |
Overview of Cellular Mechanisms and Signaling Pathways of Piceatannol.
Topics: Animals; Cardiovascular Diseases; Cell Cycle; Fabaceae; Humans; Neoplasms; Neuroprotection; Phytotherapy; Protein Kinase Inhibitors; Resveratrol; Signal Transduction; Stilbenes | 2020 |
Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity.
Topics: Animals; Antineoplastic Agents; Cellular Senescence; Humans; Neoplasms; Resveratrol; Stilbenes; Telomerase | 2019 |
Detection of Biomedically Relevant Stilbenes from Wines by Mass Spectrometry.
Topics: Humans; Mass Spectrometry; Resveratrol; Stilbenes; Wine | 2019 |
Resveratrol: a review of plant sources, synthesis, stability, modification and food application.
Topics: Animals; Humans; Plant Extracts; Plants; Resveratrol; Stilbenes | 2020 |
Tumor PD-L1 Induction by Resveratrol/Piceatannol May Function as a Search, Enhance, and Engage ("SEE") Signal to Facilitate the Elimination of "Cold, Non-Responsive" Low PD-L1-Expressing Tumors by PD-L1 Blockade.
Topics: Animals; Antineoplastic Agents; B7-H1 Antigen; Humans; Neoplasms; Resveratrol; Stilbenes | 2019 |
Aza- and Azo-Stilbenes: Bio-Isosteric Analogs of Resveratrol.
Topics: Antioxidants; Aza Compounds; Azo Compounds; Molecular Structure; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2020 |
Effects of resveratrol and its derivative pterostilbene on brown adipose tissue thermogenic activation and on white adipose tissue browning process.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Cells, Cultured; Energy Metabolism; Humans; Organelle Biogenesis; Oxidative Phosphorylation; Resveratrol; Stilbenes; Thermogenesis | 2020 |
The roles of resveratrol on cardiac mitochondrial function in cardiac diseases.
Topics: Antioxidants; Heart Diseases; Humans; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2021 |
Resveratrol: A Fair Race Towards Replacing Sulfites in Wines.
Topics: Food Storage; Humans; Phenols; Phytochemicals; Resveratrol; Stilbenes; Sulfites; Vitis; Wine | 2020 |
Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease.
Topics: Animals; Benzoquinones; Biological Products; Biomimetics; Caffeic Acids; Curcumin; Cytokines; Exosomes; Humans; Inflammation; Inflammatory Bowel Diseases; Insecta; Macromolecular Substances; Nanomedicine; Oxidative Stress; Phenylethyl Alcohol; Phytochemicals; Plant Extracts; Polysaccharides; Quercetin; Resveratrol; Stilbenes; Transcription Factors; Translational Research, Biomedical; Vasoactive Intestinal Peptide; Zingiber officinale | 2020 |
Resveratrol and other Stilbenes: Effects on Dysregulated Gene Expression in Cancers and Novel Delivery Systems.
Topics: Antineoplastic Agents, Phytogenic; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Liposomes; Molecular Structure; Nanoparticles; Neoplasms; Resveratrol; Stilbenes | 2021 |
More Than Resveratrol: New Insights into Stilbene-Based Compounds.
Topics: Animals; Bibenzyls; Drug Discovery; Humans; Resveratrol; Stilbenes | 2020 |
The estrogenic activity of resveratrol: a comprehensive review of
Topics: Animals; Endocrine Disruptors; Estrogens; Humans; Phytoestrogens; Receptors, Estrogen; Receptors, G-Protein-Coupled; Resveratrol; Stilbenes | 2020 |
Resveratrol, a Molecule with Anti-Inflammatory and Anti-Cancer Activities: Natural Product to Chemical Synthesis.
Topics: Anti-Inflammatory Agents; Biological Products; Biosynthetic Pathways; Humans; Resveratrol; Stilbenes | 2021 |
Recent Advances in Synthesis, Bioactivity, and Pharmacokinetics of Pterostilbene, an Important Analog of Resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Humans; Hypoglycemic Agents; Inactivation, Metabolic; Intestinal Absorption; Mice; Neuroprotective Agents; Resveratrol; Stilbenes; Tissue Distribution | 2020 |
Resveratrol and cardiovascular system-the unfulfilled hopes.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cardiovascular System; Humans; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2021 |
The Potential of Resveratrol to Act as a Caloric Restriction Mimetic Appears to Be Limited: Insights from Studies in Mice.
Topics: Animals; Caloric Restriction; Humans; Insulin; Mice; Resveratrol; Sirtuin 1; Stilbenes | 2021 |
Nonhormonal Treatment for Endometriosis Focusing on Redox Imbalance.
Topics: Animals; Antioxidants; Cabergoline; Dopamine Agonists; Endometriosis; Female; Glucosides; Humans; Methemoglobin; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Simvastatin; Stilbenes; Superoxides | 2021 |
Resveratrol and Cardiac Fibrosis Prevention and Treatment.
Topics: Animals; Fibrosis; Heart; Humans; Myocardial Infarction; Myocardium; Resveratrol; Stilbenes | 2022 |
The role of resveratrol in diabetes and obesity associated with insulin resistance.
Topics: Animals; Diabetes Mellitus; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Resveratrol; Stilbenes | 2023 |
Natural Product-Based Hybrids as Potential Candidates for the Treatment of Cancer: Focus on Curcumin and Resveratrol.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biological Products; Curcumin; Drug Delivery Systems; Gold; Humans; Metal Nanoparticles; Neoplasms; Resveratrol; Stilbenes | 2021 |
Review on target domains and natural compound-based inhibitors of fatty acid synthase for anticancer drug discovery.
Topics: Antineoplastic Agents; Biological Products; Catalytic Domain; Drug Discovery; Drug Screening Assays, Antitumor; Fatty Acid Synthases; Flavonoids; Humans; Polyphenols; Protein Binding; Resveratrol; Stilbenes; Structure-Activity Relationship | 2021 |
Recent Advances in Health Benefits of Stilbenoids.
Topics: Resveratrol; Stilbenes | 2021 |
Enhancing Bioavailability of Nutraceutically Used Resveratrol and Other Stilbenoids.
Topics: Animals; Biological Availability; Dietary Supplements; Drug Delivery Systems; Humans; Resveratrol; Stilbenes | 2021 |
Resveratrol and cyclodextrins, an easy alliance: Applications in nanomedicine, green chemistry and biotechnology.
Topics: Biotechnology; Cyclodextrins; Humans; Nanomedicine; Resveratrol; Stilbenes | 2021 |
Resveratrol as a modulatory of apoptosis and autophagy in cancer therapy.
Topics: Apoptosis; Autophagy; Humans; Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2022 |
The science of resveratrol, formulation, pharmacokinetic barriers and its chemotherapeutic potential.
Topics: Biological Availability; Humans; Neoplasms; Pharmaceutical Preparations; Resveratrol; Stilbenes | 2022 |
Stilbenes: Characterization, bioactivity, encapsulation and structural modifications. A review of their current limitations and promising approaches.
Topics: Anti-Inflammatory Agents; Antioxidants; Humans; Resveratrol; Stilbenes | 2023 |
Review on chemical compositions and biological activities of peanut (Arachis hypogeae L.).
Topics: Anti-Inflammatory Agents; Antioxidants; Arachis; Resveratrol; Stilbenes | 2022 |
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
Topics: Humans; Neurodegenerative Diseases; Polyphenols; Resveratrol; Stilbenes; Structure-Activity Relationship | 2022 |
In the shadow of resveratrol: biological activities of epsilon-viniferin.
Topics: Benzofurans; Humans; Resveratrol; Stilbenes | 2022 |
Health benefits of polyphenols: A concise review.
Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Flavonoids; Functional Food; Humans; Lignans; Lipids; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea | 2022 |
The bioactivities of resveratrol and its naturally occurring derivatives on skin.
Topics: Animals; Antioxidants; Cosmetics; Resveratrol; Skin; Skin Diseases; Stilbenes | 2021 |
Applications of resveratrol in the treatment of gastrointestinal cancer.
Topics: Antioxidants; Gastrointestinal Neoplasms; Humans; Neoplasms; Polyphenols; Resveratrol; Stilbenes | 2022 |
Involvement of Resveratrol against Brain Cancer: A Combination Strategy with a Pharmaceutical Approach.
Topics: Antioxidants; Brain; Brain Neoplasms; Drug Delivery Systems; Humans; Pharmaceutical Preparations; Resveratrol; Stilbenes | 2022 |
The Role of Resveratrol in Eye Diseases-A Review of the Literature.
Topics: Antioxidants; Glaucoma; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2022 |
Resveratrol Effects on Molecular Pathways and MicroRNAs in Gastrointestinal Cancers.
Topics: Fruit; Gastrointestinal Neoplasms; Humans; MicroRNAs; Resveratrol; Stilbenes | 2023 |
Research Progress in Elucidating the Mechanisms Underlying Resveratrol Action on Lung Cancer.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Lung Neoplasms; Male; Resveratrol; Signal Transduction; Stilbenes | 2023 |
Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol.
Topics: Anti-Inflammatory Agents; Antiviral Agents; NF-kappa B; Resveratrol; Stilbenes | 2022 |
Chemistry, Biosynthesis and Pharmacology of Viniferin: Potential Resveratrol-Derived Molecules for New Drug Discovery, Development and Therapy.
Topics: Antioxidants; Antiviral Agents; Drug Discovery; Pharmaceutical Preparations; Resveratrol; Stilbenes | 2022 |
Recent Overview of Resveratrol's Beneficial Effects and Its Nano-Delivery Systems.
Topics: Antioxidants; Nanoparticle Drug Delivery System; Polyphenols; Resveratrol; Stilbenes | 2022 |
Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Docetaxel; Doxorubicin; Female; Humans; Paclitaxel; Polyphenols; Resveratrol; Stilbenes; Tumor Microenvironment; Water | 2022 |
New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects.
Topics: Antioxidants; Health Promotion; Humans; NF-E2-Related Factor 2; Resveratrol; Stilbenes | 2022 |
Polydatin: Pharmacological Mechanisms, Therapeutic Targets, Biological Activities, and Health Benefits.
Topics: Female; Glucosides; Humans; Polyphenols; Resveratrol; Stilbenes | 2022 |
Benefits of skin application of piceatannol-A minireview.
Topics: Antioxidants; Humans; Resveratrol; Skin; Stilbenes | 2023 |
Effects of resveratrol supplementation on nitric oxide-mediated vascular outcomes in hypertension: A systematic review.
Topics: Animals; Antioxidants; Dietary Supplements; Endothelium, Vascular; Humans; Hypertension; Nitric Oxide; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes | 2022 |
Progress in the Preclinical and Clinical Study of Resveratrol for Vascular Metabolic Disease.
Topics: Endothelial Cells; Fatty Acids; Humans; Lipid Metabolism; Metabolic Diseases; Resveratrol; Stilbenes; Vascular Diseases | 2022 |
Mechanism of Resveratrol-Induced Programmed Cell Death and New Drug Discovery against Cancer: A Review.
Topics: Antineoplastic Agents; Apoptosis; Drug Discovery; Humans; Neoplasms; Resveratrol; Stilbenes | 2022 |
Resveratrol and SIRT1: Antiaging Cornerstones for Oocytes?
Topics: Aging; Animals; Antioxidants; Mammals; Oocytes; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes | 2022 |
Beneficial Effects of ε-Viniferin on Obesity and Related Health Alterations.
Topics: Animals; Diabetes Mellitus, Type 2; Female; Humans; Male; Mice; Obesity; Resveratrol; Stilbenes; Vitis | 2023 |
Production of high molecular-ordered stilbene oligomers for the study of their biological activity: total synthesis, bio-catalyzed synthesis and production by plant systems.
Topics: Catalysis; Resveratrol; Stilbenes | 2023 |
Between the Devil and the Deep Blue Sea-Resveratrol, Sulfotransferases and Sulfatases-A Long and Turbulent Journey from Intestinal Absorption to Target Cells.
Topics: Animals; Antioxidants; Humans; Intestinal Absorption; Resveratrol; Stilbenes; Sulfatases; Sulfotransferases | 2023 |
Sirtuins, resveratrol and the intertwining cellular pathways connecting them.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Humans; NF-kappa B; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2023 |
Stilbenes, a Versatile Class of Natural Metabolites for Inflammation-An Overview.
Topics: Animals; Fruit; Humans; Inflammation; Resveratrol; Stilbenes; Vitis | 2023 |
Analytics, Properties and Applications of Biologically Active Stilbene Derivatives.
Topics: Antifungal Agents; COVID-19; Humans; Preservatives, Pharmaceutical; Resveratrol; Stilbenes | 2023 |
Resveratrol, a Multitasking Molecule That Improves Skeletal Muscle Health.
Topics: Animals; Caloric Restriction; Humans; Muscle, Skeletal; Polyphenols; Resveratrol; Stilbenes | 2023 |
The Pharmacological Properties of Red Grape Polyphenol Resveratrol: Clinical Trials and Obstacles in Drug Development.
Topics: Antioxidants; Drug Development; Polyphenols; Resveratrol; Stilbenes; Vitis | 2023 |
158 trial(s) available for resveratrol and stilbenes
| Article | Year |
|---|---|
Effects of red wine and wine polyphenol resveratrol on platelet aggregation in vivo and in vitro.
Topics: Animals; China; Humans; Hypercholesterolemia; In Vitro Techniques; Lipids; Male; Platelet Aggregation; Rabbits; Rats; Resveratrol; Stilbenes; Wine | 2002 |
Inhibition by red wine extract, resveratrol, of cytokine release by alveolar macrophages in COPD.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bronchoalveolar Lavage Fluid; Cytokines; Female; Humans; In Vitro Techniques; Interleukin-1; Macrophages, Alveolar; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Resveratrol; Smoke; Smoking; Stilbenes; Wine | 2003 |
Selective COX-2 inhibition by a Pterocarpus marsupium extract characterized by pterostilbene, and its activity in healthy human volunteers.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Inhibitory Concentration 50; Leukocytes, Mononuclear; Male; Phenols; Phytotherapy; Plant Extracts; Pterocarpus; Resveratrol; Stilbenes | 2005 |
Effects of resveratrol on vascular tone and endothelial function of human saphenous vein and internal mammary artery.
Topics: Acetylcholine; Antioxidants; Coronary Artery Bypass; Endothelium, Vascular; Female; Follow-Up Studies; Humans; In Vitro Techniques; Indomethacin; Male; Mammary Arteries; Middle Aged; Myocardial Ischemia; Norepinephrine; Resveratrol; Saphenous Vein; Stilbenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Acute responses to phytoestrogens in small arteries from men with coronary heart disease.
Topics: Administration, Oral; Adult; Aged; Arteries; Coronary Disease; Genistein; Humans; Male; Middle Aged; Nitric Oxide; Phytoestrogens; Resveratrol; Stilbenes; Time Factors; Treatment Outcome; Vasodilation | 2006 |
Diagnostic performance of urinary resveratrol metabolites as a biomarker of moderate wine consumption.
Topics: Adult; Alcohol Drinking; Biomarkers; Cohort Studies; Cross-Over Studies; Female; Humans; Male; Multicenter Studies as Topic; Predictive Value of Tests; Prospective Studies; Resveratrol; ROC Curve; Sensitivity and Specificity; Single-Blind Method; Stilbenes; Wine | 2006 |
Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent.
Topics: Adult; Anticarcinogenic Agents; Area Under Curve; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasms; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2007 |
Resveratrol, at concentrations attainable with moderate wine consumption, stimulates human platelet nitric oxide production.
Topics: Adult; Blood Platelets; Cell Adhesion Molecules; Cells, Cultured; Female; Humans; Male; Microfilament Proteins; Middle Aged; NADPH Oxidases; Nitrates; Nitric Oxide; Nitrites; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Wine | 2008 |
Effect of food on the pharmacokinetic profile of trans-resveratrol.
Topics: Administration, Oral; Adult; Antioxidants; Area Under Curve; Biological Availability; Confidence Intervals; Cross-Over Studies; Fasting; Female; Food; Half-Life; Humans; Male; Resveratrol; Stilbenes; Wine | 2008 |
Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers.
Topics: Adult; Biological Availability; Circadian Rhythm; Double-Blind Method; Female; Humans; Kinetics; Male; Placebos; Resveratrol; Stilbenes | 2009 |
Inhibition of low-density lipoprotein oxidation by Nagano purple grape (Vitis viniferaxVitis labrusca).
Topics: Adult; Anthocyanins; Antioxidants; Cholesterol, LDL; Fruit; Glucosides; Humans; Lipid Peroxidation; Male; Middle Aged; Plant Preparations; Resveratrol; Stilbenes; Vitis | 2009 |
Intake of red wine increases the number and functional capacity of circulating endothelial progenitor cells by enhancing nitric oxide bioavailability.
Topics: AC133 Antigen; Adult; Alcoholic Beverages; Antigens, CD; Antigens, CD34; Arginine; Beer; Biological Availability; Biomarkers; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Endothelial Cells; Enzyme Inhibitors; Ethanol; Female; Flow Cytometry; Glycoproteins; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prospective Studies; Proto-Oncogene Proteins c-akt; Resveratrol; Stem Cells; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor Receptor-2; Vasodilation; Wine | 2010 |
Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation.
Topics: Adolescent; Adult; Cerebrovascular Circulation; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Frontal Lobe; Hemoglobins; Humans; Male; Resveratrol; Spectroscopy, Near-Infrared; Stilbenes; Vasodilator Agents; Young Adult | 2010 |
Effects of dietary resveratrol supplementation on egg production and antioxidant status.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Female; Oviposition; Resveratrol; Stilbenes | 2010 |
Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects.
Topics: Adult; Area Under Curve; Chromatography, Liquid; Diarrhea; Diet; Drug Administration Schedule; Drug Combinations; Drug Tolerance; Ethanol; Female; Humans; Male; Middle Aged; Pharmacokinetics; Quercetin; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2010 |
An antiinflammatory and reactive oxygen species suppressive effects of an extract of Polygonum cuspidatum containing resveratrol.
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Cytokines; Fallopia japonica; Gene Expression Regulation; Humans; Inflammation Mediators; Insulin; Leptin; Lipids; Oxidative Stress; Placebos; Plant Extracts; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure.
Topics: Brachial Artery; Cardiovascular Diseases; Cross-Over Studies; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Obesity; Overweight; Placebos; Resveratrol; Risk Factors; Stilbenes; Vasodilation | 2011 |
Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer study.
Topics: Adult; Antineoplastic Agents, Phytogenic; Carcinogens; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Activation; Female; Health; Healthy Volunteers; Humans; Inactivation, Metabolic; Male; Middle Aged; Pharmaceutical Preparations; Resveratrol; Stilbenes; Young Adult | 2010 |
Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cell Growth Processes; Colorectal Neoplasms; Combined Modality Therapy; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Middle Aged; Resveratrol; Stilbenes | 2010 |
Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis.
Topics: Abdominal Pain; Adult; Antineoplastic Agents, Phytogenic; Area Under Curve; Chromatography, High Pressure Liquid; Diarrhea; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucuronides; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Metabolic Clearance Rate; Middle Aged; Nausea; Resveratrol; Stilbenes; Young Adult | 2010 |
A sensitive resveratrol assay with a simple probe methylene blue by resonance light scattering technique.
Topics: Absorption; Biological Assay; Calibration; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Ions; Light; Limit of Detection; Male; Methylene Blue; Microscopy, Electron, Scanning; Reference Standards; Resveratrol; Scattering, Radiation; Spectrometry, Fluorescence; Static Electricity; Stilbenes; Time Factors | 2011 |
Resveratrol protects quail hepatocytes against heat stress: modulation of the Nrf2 transcription factor and heat shock proteins.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cells, Cultured; Diet; Female; Heat-Shock Proteins; Hepatocytes; Hot Temperature; NF-E2-Related Factor 2; Oviposition; Oxidative Stress; Quail; Resveratrol; Stilbenes | 2012 |
Resveratrol-containing gel for the treatment of acne vulgaris: a single-blind, vehicle-controlled, pilot study.
Topics: Acne Vulgaris; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Carboxymethylcellulose Sodium; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Female; Humans; Hydrogels; Male; Pharmaceutical Vehicles; Photography; Pilot Projects; Propionibacterium acnes; Resveratrol; Single-Blind Method; Stilbenes; Treatment Outcome; Young Adult | 2011 |
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.
Topics: Adult; Blood Platelets; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Insulin Resistance; Male; Middle Aged; Oxidative Stress; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Tyrosine | 2011 |
Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases--safety, pharmacokinetics, and pharmacodynamics.
Topics: Aged; Antineoplastic Agents, Phytogenic; Caspase 3; Combined Modality Therapy; Double-Blind Method; Female; Hepatectomy; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Pilot Projects; Placebos; Postoperative Complications; Resveratrol; Stilbenes; Titanium | 2011 |
CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Embryo, Mammalian; Female; Glutamic Acid; Humans; L-Lactate Dehydrogenase; Male; Middle Aged; Motor Neurons; Neuroprotective Agents; Pregnancy; Rats; Resveratrol; Riluzole; Stilbenes | 2011 |
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
Topics: Adipose Tissue; Alanine Transaminase; AMP-Activated Protein Kinase Kinases; Blood Glucose; Blood Pressure; Caloric Restriction; Citrate (si)-Synthase; Cross-Over Studies; Double-Blind Method; Energy Metabolism; Fatty Acids; Glycerol; Heat-Shock Proteins; Humans; Liver; Male; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Netherlands; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Kinases; Resveratrol; Sirtuin 1; Stilbenes; Switzerland; Transcription Factors; Triglycerides | 2011 |
Modified resveratrol Longevinex improves endothelial function in adults with metabolic syndrome receiving standard treatment.
Topics: Aged; Diabetes Mellitus; Drug Compounding; Endothelium, Vascular; Female; Humans; Hyperlipidemias; Hypertension; Insulin Resistance; Life Style; Male; Metabolic Syndrome; Middle Aged; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents | 2011 |
Pilot study of resveratrol in older adults with impaired glucose tolerance.
Topics: Aged; Antioxidants; Blood Glucose; Endothelium, Vascular; Female; Glucose Intolerance; Homeostasis; Humans; Male; Pilot Projects; Resveratrol; Stilbenes | 2012 |
Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease.
Topics: Aged; Antioxidants; Brachial Artery; Coronary Artery Disease; Double-Blind Method; Endothelium, Vascular; Erythrocyte Deformability; Female; Humans; Male; Myocardial Infarction; Placebos; Platelet Aggregation; Resveratrol; Stilbenes; Vasodilation; Ventricular Function, Left | 2012 |
Trans-resveratrol alters mammary promoter hypermethylation in women at increased risk for breast cancer.
Topics: Breast; Breast Neoplasms; Cyclin D2; Dinoprostone; DNA Methylation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Middle Aged; Promoter Regions, Genetic; Resveratrol; Risk Factors; Stilbenes; Tumor Suppressor Proteins | 2012 |
High urinary levels of resveratrol metabolites are associated with a reduction in the prevalence of cardiovascular risk factors in high-risk patients.
Topics: Aged; Biomarkers; Biotransformation; Blood Glucose; Cardiovascular Diseases; Chromatography, Liquid; Cross-Sectional Studies; Diet, Mediterranean; Female; Heart Rate; Humans; Linear Models; Lipoproteins, HDL; Male; Middle Aged; Multivariate Analysis; Prevalence; Resveratrol; Solid Phase Extraction; Spain; Stilbenes; Tandem Mass Spectrometry; Triglycerides; Wine | 2012 |
One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Female; Fibrinolysis; Fruit; Humans; Inflammation; Male; Middle Aged; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Time Factors; Vitis | 2012 |
Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
Topics: Aged; Apolipoproteins B; Cardiovascular Diseases; Dietary Supplements; Female; Follow-Up Studies; Humans; Kidney; Lipids; Lipoproteins, LDL; Liver; Male; Middle Aged; Plant Extracts; Resveratrol; Stilbenes; Thyroid Function Tests; Vitis | 2012 |
Effect of the intake of resveratrol, resveratrol phosphate, and catechin-rich grape seed extract on markers of oxidative stress and gene expression in adult obese subjects.
Topics: Adult; Antioxidants; Biomarkers; Catechin; Dietary Supplements; Female; Gene Expression; Grape Seed Extract; Humans; Male; Microarray Analysis; Middle Aged; Obesity; Organophosphates; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus.
Topics: Administration, Oral; Aged; Blood Glucose; Body Mass Index; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; India; Male; Middle Aged; Nitrogen; Prospective Studies; Resveratrol; Risk Factors; Stilbenes | 2012 |
Pharmacokinetics of resveratrol metabolic profile in healthy humans after moderate consumption of red wine and grape extract tablets.
Topics: Adult; Dietary Supplements; Glucosides; Humans; Male; Plant Extracts; Resveratrol; Stilbenes; Tablets; Vitis; Wine; Young Adult | 2012 |
Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium.
Topics: Atherosclerosis; Double-Blind Method; Endothelium, Vascular; Female; Gene Expression Regulation; Humans; Male; Resveratrol; Stilbenes | 2013 |
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance.
Topics: Adipose Tissue; Antioxidants; Body Composition; Dietary Supplements; Double-Blind Method; Drug Administration Schedule; Female; Gene Expression Regulation; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Liver; Middle Aged; Muscle, Skeletal; Placebo Effect; Resveratrol; Stilbenes | 2012 |
Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of life.
Topics: Administration, Oral; Aged; Angina, Stable; Borates; C-Reactive Protein; Dietary Supplements; Double-Blind Method; Female; Fructose; Humans; Inflammation Mediators; Lipids; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Quality of Life; Resveratrol; Stilbenes | 2013 |
High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.
Topics: Adolescent; Adult; Aged; Antioxidants; Body Composition; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Energy Metabolism; Gene Expression Regulation; Humans; Insulin Resistance; Male; Middle Aged; Obesity; Pilot Projects; Resveratrol; Stilbenes; Young Adult | 2013 |
A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Creatinine; Dehydration; Drug Resistance, Neoplasm; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Multiple Myeloma; Pyrazines; Recurrence; Remission Induction; Resveratrol; Salvage Therapy; Stilbenes; Treatment Failure; Vomiting | 2013 |
Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral blood mononuclear cells: a triple-blind, placebo-controlled, one-year clinical trial in patients with stable coronary artery disease.
Topics: Adiponectin; Anti-Inflammatory Agents; Coronary Artery Disease; Dietary Supplements; Down-Regulation; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Plant Extracts; Research Design; Resveratrol; Stilbenes; Transcription Factors; Treatment Outcome; Vitis | 2013 |
In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota.
Topics: Actinobacteria; Adult; Bibenzyls; Dietary Supplements; Feces; Female; Fermentation; Humans; Hydroxylation; Kinetics; Male; Middle Aged; Molecular Structure; Molecular Typing; Phenols; Resveratrol; Stereoisomerism; Stilbenes; Young Adult | 2013 |
Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial.
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; C-Reactive Protein; Cardiovascular Diseases; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Placebo Effect; Resveratrol; Risk Factors; Smoking; Stilbenes; Triglycerides | 2013 |
Optimization of trans-Resveratrol bioavailability for human therapy.
Topics: Administration, Oral; Adult; Aged; Animals; Antioxidants; Biological Availability; Capsules; Chromatography, High Pressure Liquid; Cross-Over Studies; Female; Humans; Male; Mice; Middle Aged; Powders; Resveratrol; Stilbenes | 2013 |
One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Coronary Artery Disease; Cytokines; Diabetes Mellitus, Type 2; Dietary Supplements; Gene Expression Regulation; Humans; Hypertension; Inflammation; Leukocytes, Mononuclear; Male; MicroRNAs; Middle Aged; Models, Molecular; Plant Extracts; Resveratrol; Stilbenes; Transcriptome; Vitis | 2013 |
Resveratrol ameliorates the oxidative damage induced by arsenic trioxide in the feline lung.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Arsenic Trioxide; Arsenicals; Cat Diseases; Cats; Deoxyguanosine; Female; Gene Expression Regulation, Enzymologic; Lung Diseases; Male; Oxidative Stress; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects.
Topics: Antioxidants; Blood Glucose; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Fasting; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Humans; Incretins; Male; Middle Aged; Obesity; Postprandial Period; Resveratrol; Stilbenes; Time Factors; Treatment Outcome | 2013 |
Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
Topics: Adult; Aged; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Mass Index; Brachial Artery; Carotid Arteries; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Obesity; Overweight; Postmenopause; Resveratrol; Stilbenes; Stroop Test; Surveys and Questionnaires; Vasodilation | 2013 |
Enhanced antioxidant effect of trans-resveratrol: potential of binary systems with polyethylene glycol and cyclodextrin.
Topics: Aged; Antioxidants; beta-Cyclodextrins; Cell Line; Chemistry, Pharmaceutical; Colorimetry; Excipients; Female; Humans; Hydrogen Peroxide; Keratinocytes; Middle Aged; Polyethylene Glycols; Reactive Oxygen Species; Resveratrol; Single-Blind Method; Skin Aging; Solubility; Stilbenes | 2014 |
Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men.
Topics: Aged; Cardiovascular System; Cholesterol, LDL; Double-Blind Method; Epoprostenol; Exercise; Humans; Male; Muscle, Skeletal; Oxygen Consumption; Resveratrol; Sedentary Behavior; Stilbenes; Thromboxane-A Synthase; Triglycerides; Vascular Cell Adhesion Molecule-1 | 2013 |
Reduction of facial redness with resveratrol added to topical product containing green tea polyphenols and caffeine.
Topics: Administration, Cutaneous; Adult; Antioxidants; Caffeine; Dermatologic Agents; Drug Combinations; Facial Dermatoses; Female; Humans; Male; Polyphenols; Resveratrol; Stilbenes; Tea; Time Factors; Treatment Outcome | 2013 |
Effect of an extra-virgin olive oil enriched with probiotics or antioxidants on functional dyspepsia: a pilot study.
Topics: Antioxidants; Carotenoids; Diet; Dietary Fats, Unsaturated; Dyspepsia; Humans; Lacticaseibacillus rhamnosus; Limosilactobacillus reuteri; Lycopene; Olive Oil; Pilot Projects; Plant Oils; Probiotics; Resveratrol; Saccharomyces; Selenium; Stilbenes; Ubiquinone | 2013 |
Aortic wave velocity: a noninvasive method to measure the stiffness of arteries and the clinical results of supplements that appear to improve arterial stiffness.
Topics: Adult; Aged; Aging; Arginine; Cardiovascular Diseases; Carnosine; Dietary Supplements; Female; Glycation End Products, Advanced; Guanidines; Humans; Male; Middle Aged; Pulse Wave Analysis; Resveratrol; Risk Factors; Stilbenes; Vascular Stiffness | 2013 |
Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle SIRT1 expression and energy expenditure.
Topics: AMP-Activated Protein Kinases; Basal Metabolism; Diabetes Mellitus, Type 2; Double-Blind Method; Energy Metabolism; Exercise; Glucose Transporter Type 4; Humans; Insulin Resistance; Male; Middle Aged; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Exertion; Plant Extracts; Rest; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors; Vitis | 2014 |
The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adult; Aged; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Gene Expression Profiling; Humans; Male; Middle Aged; Obesity; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes; Treatment Outcome; Wnt Signaling Pathway | 2014 |
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.
Topics: Animals; beta-Thalassemia; Catalase; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Erythropoiesis; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Male; Mice; Peroxiredoxins; Resveratrol; Stilbenes | 2014 |
Resveratrol enhances TNF-α production in human monocytes upon bacterial stimulation.
Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Cytokines; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Monocytes; NF-kappa B; Phosphorylation; Pilot Projects; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Young Adult | 2014 |
High-dose resveratrol treatment for 2 weeks inhibits intestinal and hepatic lipoprotein production in overweight/obese men.
Topics: Adult; Analysis of Variance; Apolipoprotein B-100; Apolipoprotein B-48; Biomarkers; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Lipoproteins; Liver; Male; Middle Aged; Obesity; Ontario; Overweight; Resveratrol; Stilbenes; Time Factors; Treatment Outcome; Triglycerides | 2013 |
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway.
Topics: Aged; Antineoplastic Agents, Phytogenic; beta Catenin; Cell Line, Tumor; Cell Nucleus; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 7; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Resveratrol; RNA, Long Noncoding; RNA, Neoplasm; Stilbenes; Wnt Signaling Pathway | 2013 |
Resveratrol metabolic fingerprinting after acute and chronic intakes of a functional beverage in humans.
Topics: Adult; Beverages; Chromatography, High Pressure Liquid; Double-Blind Method; Eating; Female; Functional Food; Gastrointestinal Tract; Humans; Male; Metabolome; Middle Aged; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Vitis | 2014 |
Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects.
Topics: Adult; Antioxidants; Body Mass Index; Catechin; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Energy Metabolism; Female; Humans; Lipid Metabolism; Male; Middle Aged; Overweight; Oxidation-Reduction; Polyphenols; Postprandial Period; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
Efficacy of food supplement to improve metabolic syndrome parameters in patients affected by moderate to severe psoriasis during anti-TNFα treatment.
Topics: Adult; Animals; Antioxidants; Biomarkers; Body Mass Index; Cholesterol, HDL; Dietary Fats, Unsaturated; Dietary Supplements; Etanercept; Euphausiacea; Female; Follow-Up Studies; Humans; Immunoglobulin G; Immunosuppressive Agents; Male; Metabolic Syndrome; Middle Aged; Psoriasis; Receptors, Tumor Necrosis Factor; Resveratrol; Seeds; Selenium; Severity of Illness Index; Stilbenes; Thioctic Acid; Treatment Outcome; Triglycerides; Tumor Necrosis Factor-alpha; Ubiquinone; Vitamin E; Vitis | 2013 |
Exercise training, but not resveratrol, improves metabolic and inflammatory status in skeletal muscle of aged men.
Topics: Aged; Citrate (si)-Synthase; Cyclooxygenase 1; Double-Blind Method; Exercise; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; I-kappa B Proteins; Male; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Stilbenes; Transcription Factors; Tumor Necrosis Factor-alpha | 2014 |
Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in black-boned chickens.
Topics: Animals; Antioxidants; Biomarkers; Chickens; Female; Gene Expression Regulation; Growth Hormone; Heat-Shock Proteins; Insulin-Like Growth Factor I; Resveratrol; RNA, Messenger; Stilbenes | 2014 |
Resveratrol does not benefit patients with nonalcoholic fatty liver disease.
Topics: Abdominal Fat; Adult; Aged; Australia; Gastrointestinal Agents; Humans; Insulin Resistance; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Placebos; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
Development of a lozenge for oral transmucosal delivery of trans-resveratrol in humans: proof of concept.
Topics: Administration, Mucosal; Administration, Oral; Adult; Biological Availability; Chemistry, Pharmaceutical; Humans; Male; Resveratrol; Ribose; Stilbenes; Water | 2014 |
Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation.
Topics: Adult; Alkaloids; Benzodioxoles; Cerebrovascular Circulation; Cognition; Cognition Disorders; Cohort Studies; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Frontal Lobe; Humans; Intestinal Absorption; Male; Nootropic Agents; Pilot Projects; Piperidines; Polyunsaturated Alkamides; Resveratrol; Spectroscopy, Near-Infrared; Stilbenes; Task Performance and Analysis; Young Adult | 2014 |
Resveratrol levels and all-cause mortality in older community-dwelling adults.
Topics: Aged; Cardiovascular Diseases; Cohort Studies; Female; Humans; Incidence; Inflammation; Italy; Male; Mortality; Neoplasms; Prevalence; Prospective Studies; Resveratrol; Stilbenes | 2014 |
A novel red grape cells complex: health effects and bioavailability of natural resveratrol.
Topics: Adult; Animals; Biological Availability; Carrageenan; Cross-Over Studies; Edema; Humans; Indomethacin; Inflammation; Lipoproteins, LDL; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitis | 2014 |
Safety and metabolic outcomes of resveratrol supplementation in older adults: results of a twelve-week, placebo-controlled pilot study.
Topics: Aged; Anthropometry; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Blood Pressure; Dietary Supplements; Female; Humans; Male; Overweight; Pilot Projects; Resveratrol; Stilbenes; Waist Circumference | 2014 |
Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
Topics: Aged; Aged, 80 and over; Antioxidants; Blood Glucose; Case-Control Studies; Cognition; Fasting; Female; Follow-Up Studies; Glycated Hemoglobin; Hippocampus; Humans; Leptin; Male; Memory; Middle Aged; Neuropsychological Tests; Quercetin; Resveratrol; Stilbenes | 2014 |
Resveratrol plus carboxymethyl-β-glucan reduces nasal symptoms in children with pollen-induced allergic rhinitis.
Topics: Administration, Intranasal; Allergens; Anti-Allergic Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Glucans; Cetirizine; Child; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Male; Pollen; Resveratrol; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Stilbenes; Treatment Outcome | 2014 |
An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo.
Topics: Acetylation; Adipose Tissue; Adult; AMP-Activated Protein Kinases; Blood Glucose; Cross-Over Studies; Double-Blind Method; Glycerol; Humans; Insulin; Male; Mitochondria; Muscle, Skeletal; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2014 |
Effect of resveratrol on exercise capacity: a randomized placebo-controlled crossover pilot study.
Topics: Adolescent; Adult; Aged; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Tolerance; Female; Humans; Male; Middle Aged; Pilot Projects; Resveratrol; Stilbenes; Young Adult | 2014 |
Modulation of growth and immunity by dietary supplementation with resveratrol in young chickens receiving conventional vaccinations.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Proliferation; Chickens; Crosses, Genetic; Cytokines; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Flow Cytometry; Insulin-Like Growth Factor I; Liver; NF-kappa B; Receptors, Somatotropin; Resveratrol; Spleen; Stilbenes; T-Lymphocytes; Vaccination | 2014 |
A pilot clinical study of resveratrol in postmenopausal women with high body mass index: effects on systemic sex steroid hormones.
Topics: Adult; Body Mass Index; Demography; Estrogens; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Pilot Projects; Postmenopause; Resveratrol; Stilbenes | 2014 |
Effect of resveratrol administration on metabolic syndrome, insulin sensitivity, and insulin secretion.
Topics: Adiposity; Adult; Area Under Curve; Biomarkers; Blood Glucose; Body Mass Index; Cholesterol, HDL; Double-Blind Method; Female; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Mexico; Middle Aged; Predictive Value of Tests; Resveratrol; Stilbenes; Time Factors; Treatment Outcome; Triglycerides; Weight Loss | 2014 |
Resveratrol plus carboxymethyl-β-glucan may affect respiratory infections in children with allergic rhinitis.
Topics: Adolescent; Child; Child, Preschool; Chitin; Drug Combinations; Fallopia japonica; Female; Glucans; Humans; Male; Nasal Sprays; Recurrence; Respiratory Tract Infections; Resveratrol; Rhinitis, Allergic; Stilbenes; Treatment Outcome | 2014 |
Resveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humans.
Topics: Adaptation, Physiological; Biopsy; Double-Blind Method; Exercise; Exercise Test; Female; Gene Expression; Humans; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Oxygen; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Young Adult | 2014 |
Resveratrol supplementation improves inflammatory biomarkers in patients with nonalcoholic fatty liver disease.
Topics: Adult; Alanine Transaminase; Anthropometry; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Cytokines; Diet; Dietary Supplements; Double-Blind Method; Exercise; Fatty Liver; Female; Humans; Inflammation Mediators; Keratin-18; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2014 |
Effect of dietary resveratrol in ameliorating aflatoxin B1-induced changes in broiler birds.
Topics: Aflatoxin B1; Animal Feed; Animals; Apoptosis; Biomarkers; Chickens; Diet; Gene Expression Regulation; Male; Oxidative Stress; Poultry Diseases; Resveratrol; Stilbenes; Weight Gain | 2015 |
Resveratrol increases bone mineral density and bone alkaline phosphatase in obese men: a randomized placebo-controlled trial.
Topics: Absorptiometry, Photon; Alkaline Phosphatase; Antioxidants; Bone and Bones; Bone Density; Double-Blind Method; Humans; Male; Metabolic Syndrome; Middle Aged; Obesity; Patient Compliance; Resveratrol; Stilbenes | 2014 |
Resveratrol plus carboxymethyl-β-glucan in children with recurrent respiratory infections: a preliminary and real-life experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Glucans; Child; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Life Change Events; Male; Recurrence; Respiratory Tract Infections; Resveratrol; Stilbenes; Treatment Outcome; Vasodilator Agents | 2014 |
Dietary resveratrol supplementation improves meat quality of finishing pigs through changing muscle fiber characteristics and antioxidative status.
Topics: Animals; Antioxidants; Chemical Phenomena; China; Crosses, Genetic; Diet; Food Quality; Gene Expression Regulation, Developmental; Glycolysis; Lipid Peroxidation; Male; Meat; Mechanical Phenomena; Muscle Fibers, Skeletal; Myosin Heavy Chains; Orchiectomy; Resveratrol; Shear Strength; Skeletal Muscle Myosins; Stilbenes; Sus scrofa | 2015 |
Effects of chronic resveratrol supplementation in military firefighters undergo a physical fitness test--a placebo-controlled, double blind study.
Topics: Adult; Alanine Transaminase; Antioxidants; Aspartate Aminotransferases; Creatine Kinase; Dietary Supplements; Double-Blind Method; Firefighters; Glutathione Peroxidase; Humans; Interleukin-6; Male; Military Personnel; Oxidative Stress; Physical Fitness; Placebo Effect; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Cytokines; Double-Blind Method; Female; Homeostasis; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Resveratrol; Stilbenes; Ultrasonography; Young Adult | 2015 |
Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin.
Topics: Administration, Cutaneous; Adult; Antioxidants; Cosmetic Techniques; Drug Combinations; Female; Flavonoids; Gene Expression Regulation; Humans; Hyperpigmentation; Middle Aged; Prospective Studies; Rejuvenation; Resveratrol; Skin Absorption; Skin Aging; Stilbenes; Vitamin E | 2014 |
Effect of resveratrol on the pharmacokinetics of carbamazepine in healthy human volunteers.
Topics: Adult; Area Under Curve; Carbamazepine; Chromatography, Liquid; Cytochrome P-450 CYP3A; Drug Interactions; Half-Life; Healthy Volunteers; Humans; Male; Mass Spectrometry; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2015 |
Resveratrol does not influence metabolic risk markers related to cardiovascular health in overweight and slightly obese subjects: a randomized, placebo-controlled crossover trial.
Topics: Aged; Apolipoprotein A-I; Biomarkers; Cardiovascular Diseases; Cross-Over Studies; Female; Humans; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Obesity; Overweight; Resveratrol; Stilbenes | 2015 |
An open-label trial in Friedreich ataxia suggests clinical benefit with high-dose resveratrol, without effect on frataxin levels.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Antioxidants; Deoxyguanosine; F2-Isoprostanes; Female; Fourier Analysis; Frataxin; Friedreich Ataxia; Humans; Iron-Binding Proteins; Leukocytes, Mononuclear; Male; Middle Aged; Resveratrol; RNA, Messenger; Stilbenes; Treatment Outcome; Young Adult | 2015 |
Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men.
Topics: Aged; Androgens; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Dihydrotestosterone; Double-Blind Method; Humans; Male; Metabolic Syndrome; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Regression Analysis; Resveratrol; Stilbenes; Testosterone; Testosterone Congeners | 2015 |
Anti-Inflammatory Effects of Resveratrol in Patients with Ulcerative Colitis: A Randomized, Double-Blind, Placebo-controlled Pilot Study.
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Colitis, Ulcerative; Double-Blind Method; Female; Humans; Male; Middle Aged; Pilot Projects; Quality of Life; Resveratrol; Stilbenes; Surveys and Questionnaires; Young Adult | 2015 |
A combination of isolated phytochemicals and botanical extracts lowers diastolic blood pressure in a randomized controlled trial of hypertensive subjects.
Topics: Adult; Antihypertensive Agents; Antioxidants; Blood Pressure; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hypertension; Magnoliopsida; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type III; Phytochemicals; Phytotherapy; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2016 |
Aterofisiol(®) in carotid plaque evolution.
Topics: Adult; Aged; Aspirin; Carotid Stenosis; Dietary Supplements; Double-Blind Method; Endarterectomy, Carotid; Fatty Acids, Omega-3; Female; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Proanthocyanidins; Prospective Studies; Resveratrol; Stilbenes; Vitamins | 2015 |
The effects of resveratrol supplementation on cardiovascular risk factors in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Topics: Adult; Alanine Transaminase; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Blood Pressure; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Fatty Liver; Female; Humans; Insulin Resistance; Lipid Metabolism; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Extracts; Resveratrol; Risk Factors; Stilbenes; Triglycerides | 2015 |
Proposed trial: safety and efficacy of resveratrol for the treatment of non-alcoholic fatty liver disease (NAFLD) and associated insulin resistance in adolescents who are overweight or obese adolescents - rationale and protocol.
Topics: Administration, Oral; Adolescent; Dietary Supplements; Double-Blind Method; Female; Humans; Insulin Resistance; Male; Non-alcoholic Fatty Liver Disease; Overweight; Pediatric Obesity; Resveratrol; Stilbenes | 2015 |
The effectiveness of different neuroprotective agents in facial nerve injury: An experimental study.
Topics: Animals; Caspase 3; Caspase 6; Dexamethasone; Electrophysiology; Facial Nerve Injuries; Immunohistochemistry; In Situ Nick-End Labeling; Nerve Regeneration; Neuroprotective Agents; Oxytocin; Prospective Studies; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans.
Topics: Adolescent; Adult; Affect; Blood Pressure; Cerebrovascular Circulation; Cognition; Diet; Dietary Supplements; Double-Blind Method; Female; Fruit; Humans; Male; Resveratrol; Sleep; Stilbenes; Surveys and Questionnaires; Task Performance and Analysis; Vegetables; Young Adult | 2015 |
A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Resveratrol; Stilbenes | 2015 |
Resveratrol improves delayed r-tPA treatment outcome by reducing MMPs.
Topics: Aged; Antioxidants; Female; Fibrinolytic Agents; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Resveratrol; Stilbenes; Stroke; Time Factors; Tissue Plasminogen Activator; Treatment Outcome | 2016 |
[Preliminary data on the effectiveness of resveratrol in a new formulation in treatment of hot flushes].
Topics: Cross-Over Studies; Double-Blind Method; Female; Hot Flashes; Humans; Italy; Menopause; Middle Aged; Pilot Projects; Quality of Life; Resveratrol; Stilbenes; Treatment Outcome | 2015 |
Administration of resveratrol for 5 wk has no effect on glucagon-like peptide 1 secretion, gastric emptying, or glycemic control in type 2 diabetes: a randomized controlled trial.
Topics: Aged; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Energy Intake; Female; Gastric Emptying; Glucagon-Like Peptide 1; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Male; Postprandial Period; Resveratrol; Stilbenes | 2016 |
White bread enriched with polyphenol extracts shows no effect on glycemic response or satiety, yet may increase postprandial insulin economy in healthy participants.
Topics: Adansonia; Adult; Antioxidants; Bread; Cross-Over Studies; Female; Food Handling; Food, Fortified; Fruit; Glycemic Index; Grape Seed Extract; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Plant Extracts; Postprandial Period; Resveratrol; Satiety Response; Single-Blind Method; Stilbenes; Tea; Young Adult | 2016 |
Influence of exercise training with resveratrol supplementation on skeletal muscle mitochondrial capacity.
Topics: Adolescent; Alkaloids; Benzodioxoles; Dietary Supplements; Double-Blind Method; Exercise; Female; Humans; Linear Models; Longitudinal Studies; Male; Mitochondria; Muscle, Skeletal; Physical Endurance; Piperidines; Polyunsaturated Alkamides; Resveratrol; Spectroscopy, Near-Infrared; Stilbenes; Young Adult | 2016 |
Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers.
Topics: Adult; Area Under Curve; Chlorzoxazone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Fasting; Half-Life; Healthy Volunteers; Herb-Drug Interactions; Humans; Male; Plant Extracts; Resveratrol; Stilbenes; Young Adult | 2016 |
Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Male; Middle Aged; Peritoneal Dialysis; Prospective Studies; Resveratrol; Stilbenes; Ultrafiltration | 2016 |
[Resveratrol increases sirtuin 1 expression in peripheral blood mononuclear cells of premature infants and inhibits the oxidative stress induced by hyperoxia in vivo].
Topics: Female; Humans; Hyperoxia; Infant, Newborn; Infant, Premature; Leukocytes, Mononuclear; Lipid Peroxidation; Male; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease.
Topics: Antioxidants; Double-Blind Method; Female; Humans; Male; Non-alcoholic Fatty Liver Disease; Prospective Studies; Resveratrol; Stilbenes | 2016 |
Resveratrol Supplementation in Schizophrenia Patients: A Randomized Clinical Trial Evaluating Serum Glucose and Cardiovascular Risk Factors.
Topics: Adult; Aged; Antioxidants; Blood Glucose; Cardiovascular Diseases; Cholesterol; Dietary Supplements; Double-Blind Method; Humans; Male; Middle Aged; Plant Extracts; Resveratrol; Risk Factors; Schizophrenia; Stilbenes; Triglycerides; Young Adult | 2016 |
Effect of Resveratrol-Based Nutritional Supplement on Choroidal Thickness: A Pilot Study.
Topics: Administration, Oral; Adult; Antioxidants; Choroid; Dietary Supplements; Double-Blind Method; Female; Follow-Up Studies; Healthy Volunteers; Humans; Male; Pilot Projects; Prospective Studies; Resveratrol; Stilbenes; Tomography, Optical Coherence; Young Adult | 2016 |
Clinical Evaluation of Effects of Chronic Resveratrol Supplementation on Cerebrovascular Function, Cognition, Mood, Physical Function and General Well-Being in Postmenopausal Women-Rationale and Study Design.
Topics: Affect; Aged; Aged, 80 and over; Cerebrovascular Circulation; Clinical Protocols; Cognition; Cognition Disorders; Dementia; Dietary Supplements; Double-Blind Method; Female; Health Status; Humans; Mental Health; Middle Aged; Neuropsychological Tests; New South Wales; Phytoestrogens; Postmenopause; Regional Blood Flow; Research Design; Resveratrol; Risk Factors; Stilbenes; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2016 |
Low dose resveratrol improves cerebrovascular function in type 2 diabetes mellitus.
Topics: Aged; Blood Flow Velocity; Cerebrovascular Circulation; Cerebrovascular Disorders; Cognition; Cognition Disorders; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Middle Cerebral Artery; Posterior Cerebral Artery; Resveratrol; Stilbenes; Time Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Vasodilation; Victoria | 2016 |
Alterations of antioxidant status in asymptomatic hypercholesterolemic individuals after resveratrol intake.
Topics: Adult; Aged; Antioxidants; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Drug Synergism; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Nutritional Status; Oxidative Stress; Resveratrol; Stilbenes; Triglycerides; Vitamin E; Waist Circumference; Young Adult | 2015 |
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial.
Topics: Adult; Blood Glucose; Catechin; Dietary Supplements; Double-Blind Method; Energy Metabolism; Fasting; Female; Humans; Insulin; Insulin Resistance; Intra-Abdominal Fat; Lipid Metabolism; Male; Mitochondria; Muscles; Obesity; Plant Extracts; Postprandial Period; Resveratrol; Stilbenes | 2016 |
Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Cell Line; Cross-Over Studies; Female; Glutathione; Glutathione Disulfide; Hep G2 Cells; Hesperidin; Humans; Lactoylglutathione Lyase; Male; Middle Aged; Models, Biological; Obesity; Overweight; Pyruvaldehyde; Resveratrol; Stilbenes; Young Adult | 2016 |
Efficacy of an orlistat-resveratrol combination for weight loss in subjects with obesity: A randomized controlled trial.
Topics: Adult; Aged; Anthropometry; Anti-Obesity Agents; Body Mass Index; Caloric Restriction; Diet; Double-Blind Method; Drug Therapy, Combination; Energy Intake; Female; Humans; Lactones; Leptin; Male; Mexico; Middle Aged; Obesity; Orlistat; Placebos; Resveratrol; Stilbenes; Treatment Outcome; Triglycerides; Weight Loss | 2016 |
Lack of glucuronidation products of trans-resveratrol in plasma and urine of cats.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cats; Diet; Female; Male; Resveratrol; Specific Pathogen-Free Organisms; Stilbenes | 2017 |
The efficacy of resveratrol in controlling hypertension: study protocol for a randomized, crossover, double-blinded, placebo-controlled trial.
Topics: Clinical Protocols; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Outcome Assessment, Health Care; Resveratrol; Sample Size; Stilbenes | 2016 |
Acute Resveratrol Consumption Improves Neurovascular Coupling Capacity in Adults with Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aged, 80 and over; Attention; Blood Flow Velocity; Cerebral Arteries; Cerebrovascular Circulation; Cognition; Cognition Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Middle Aged; Neurovascular Coupling; New South Wales; Resveratrol; Stilbenes; Time Factors; Trail Making Test; Treatment Outcome; Ultrasonography, Doppler, Transcranial; Vasodilation | 2016 |
Six months of resveratrol supplementation has no measurable effect in type 2 diabetic patients. A randomized, double blind, placebo-controlled trial.
Topics: Biomarkers; C-Reactive Protein; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Health Status; Humans; Inflammation Mediators; Italy; Resveratrol; Stilbenes; Time Factors; Treatment Outcome | 2016 |
Effects of Resveratrol Supplementation in Nrf2 and NF-κB Expressions in Nondialyzed Chronic Kidney Disease Patients: A Randomized, Double-Blind, Placebo-Controlled, Crossover Clinical Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Humans; Leukocytes, Mononuclear; Male; Middle Aged; NF-E2-Related Factor 2; NF-kappa B; Pilot Projects; Renal Insufficiency, Chronic; Resveratrol; Stilbenes | 2016 |
A randomized, controlled trial of the effects of resveratrol administration in performance horses with lameness localized to the distal tarsal joints.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Gait; Hindlimb; Horse Diseases; Horses; Injections, Intra-Articular; Lameness, Animal; Male; Osteoarthritis; Physical Conditioning, Animal; Resveratrol; Stilbenes; Tarsal Joints; Treatment Outcome | 2016 |
Resveratrol Supplementation and Oxidative/Anti-Oxidative Status in Patients with Ulcerative Colitis: A Randomized, Double-Blind, Placebo-controlled Pilot Study.
Topics: Adult; Antioxidants; Colitis, Ulcerative; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Pilot Projects; Prospective Studies; Quality of Life; Resveratrol; Stilbenes; Superoxide Dismutase; Surveys and Questionnaires | 2016 |
Effects of Resveratrol on Polycystic Ovary Syndrome: A Double-blind, Randomized, Placebo-controlled Trial.
Topics: Adult; Antioxidants; Dehydroepiandrosterone Sulfate; Double-Blind Method; Female; Humans; Insulin; Insulin Resistance; Outcome Assessment, Health Care; Polycystic Ovary Syndrome; Resveratrol; Stilbenes; Testosterone | 2016 |
Resveratrol improves treatment outcome and laboratory parameters in patients with Takayasu arteritis: A randomized double-blind and placebo-controlled trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Sedimentation; C-Reactive Protein; Female; Humans; Male; Middle Aged; Resveratrol; Stilbenes; Takayasu Arteritis; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2017 |
The Impact of Resveratrol Supplementation on Blood Glucose, Insulin, Insulin Resistance, Triglyceride, and Periodontal Markers in Type 2 Diabetic Patients with Chronic Periodontitis.
Topics: Blood Glucose; Chronic Periodontitis; Double-Blind Method; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Resveratrol; Stilbenes; Triglycerides | 2017 |
Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial.
Topics: Adult; Aged; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Metformin; Middle Aged; Resveratrol; Stilbenes | 2016 |
Serum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: A randomized trial.
Topics: Biomarkers; Caloric Restriction; Female; Gene Expression Regulation; Humans; Lipids; Male; Middle Aged; Overweight; Prospective Studies; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study.
Topics: Anxiety; Depression; Dietary Supplements; Double-Blind Method; Drug Combinations; Equol; Female; Hot Flashes; Humans; Menopause; Middle Aged; Phytoestrogens; Quality of Life; Resveratrol; Sexual Dysfunction, Physiological; Sleep; Stilbenes; Treatment Outcome; Vagina | 2017 |
Effects of Resveratrol on Cognitive Performance, Mood and Cerebrovascular Function in Post-Menopausal Women; A 14-Week Randomised Placebo-Controlled Intervention Trial.
Topics: Affect; Aged; Aged, 80 and over; Cerebrovascular Circulation; Cognition; Dietary Supplements; Double-Blind Method; Female; Humans; Middle Aged; Phytoestrogens; Postmenopause; Resveratrol; Stilbenes; Surveys and Questionnaires | 2017 |
Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer's disease.
Topics: Activities of Daily Living; Adaptive Immunity; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL5; Cognition Disorders; Cytokines; Double-Blind Method; Encephalitis; Female; Fibroblast Growth Factor 2; Follow-Up Studies; Humans; Male; Matrix Metalloproteinase 9; Mental Status Schedule; Peptide Fragments; Resveratrol; Stilbenes; tau Proteins | 2017 |
A Placebo-Controlled Double-Blinded Randomized Pilot Study of Combination Phytotherapy in Biochemically Recurrent Prostate Cancer.
Topics: Aged; Antineoplastic Agents, Phytogenic; Behavioral Symptoms; Biomarkers, Tumor; Brassica; Curcuma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; Quality of Life; Radiotherapy; Resveratrol; Stilbenes; Symptom Assessment; Tea; Time Factors; Treatment Outcome | 2017 |
No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial.
Topics: Absorptiometry, Photon; Adipose Tissue; Antioxidants; Blood Glucose; Blood Pressure; Blotting, Western; Body Composition; C-Reactive Protein; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Fructosamine; Humans; Insulin; Insulin Resistance; Interleukin-6; Intra-Abdominal Fat; Leptin; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolic Syndrome; Middle Aged; Muscle, Skeletal; Quadriceps Muscle; Real-Time Polymerase Chain Reaction; Receptors, Urokinase Plasminogen Activator; Resveratrol; Stilbenes; Triglycerides | 2017 |
Effects of 6 months of resveratrol versus placebo on pentraxin 3 in patients with type 2 diabetes mellitus: a double-blind randomized controlled trial.
Topics: Adult; Aged; Antioxidants; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Resveratrol; Serum Amyloid P-Component; Stilbenes; Treatment Outcome | 2017 |
Resveratrol Improves Vascular Function and Mitochondrial Number but Not Glucose Metabolism in Older Adults.
Topics: Aged; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Glucose; Humans; Male; Metabolism; Mitochondria; Resveratrol; Stilbenes | 2017 |
Resveratrol supplementation reduces pain experience by postmenopausal women.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Dietary Supplements; Double-Blind Method; Female; Humans; Middle Aged; Osteoarthritis; Pain; Pain Measurement; Phytoestrogens; Postmenopause; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women.
Topics: Adaptation, Physiological; Age Factors; Aged; Aged, 80 and over; Antioxidants; Double-Blind Method; Exercise; Female; Humans; Male; Muscle Fatigue; Muscle, Skeletal; Resveratrol; Satellite Cells, Skeletal Muscle; Stilbenes | 2017 |
The Repeated Administration of Resveratrol Has Measurable Effects on Circulating T-Cell Subsets in Humans.
Topics: Adult; Antioxidants; Cell Movement; Cell Proliferation; Chemokines; Female; Humans; Male; Middle Aged; Oxidative Stress; Receptors, Antigen, T-Cell, gamma-delta; Resveratrol; Stilbenes; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2017 |
Gut microbiota composition in relation to the metabolic response to 12-week combined polyphenol supplementation in overweight men and women.
Topics: Absorptiometry, Photon; Adult; Bacteroidetes; Catechin; Double-Blind Method; Energy Metabolism; Faecalibacterium prausnitzii; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Muscle, Skeletal; Overweight; Polyphenols; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol Ameliorates Arterial Stiffness Assessed by Cardio-Ankle Vascular Index in Patients With Type 2 Diabetes Mellitus.
Topics: Administration, Oral; Ankle Brachial Index; Antioxidants; Atherosclerosis; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidative Stress; Resveratrol; Retrospective Studies; Stilbenes; Treatment Outcome; Vascular Stiffness | 2017 |
Resveratrol in Hepatitis C Patients Treated with Pegylated-Interferon-α-2b and Ribavirin Reduces Sleep Disturbance.
Topics: Acetylcysteine; Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Blood Glucose; Body Mass Index; C-Reactive Protein; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Lactoferrin; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; Quality of Life; Recombinant Proteins; Resveratrol; Ribavirin; Sleep Wake Disorders; Stilbenes; Surveys and Questionnaires | 2017 |
Resveratrol supplementation improves lipid and glucose metabolism in high-fat diet-fed blunt snout bream.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Cyprinidae; Diet; Diet, High-Fat; Dietary Fats; Dietary Supplements; Glucose; Lipid Metabolism; Models, Biological; Resveratrol; Stilbenes | 2018 |
Evolution of pain at 3 months by oral resveratrol in knee osteoarthritis (ARTHROL): protocol for a multicentre randomised double-blind placebo-controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; France; Humans; Knee Joint; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Research Design; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol improves efficacy of oral amoxicillin against childhood fast breathing pneumonia in a randomized placebo-controlled double blind clinical trial.
Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Child, Preschool; China; Double-Blind Method; Female; Humans; Infant; Male; Pneumonia; Respiratory System Agents; Resveratrol; Stilbenes; Treatment Outcome | 2018 |
Impact of sirtuin-1 expression on H3K56 acetylation and oxidative stress: a double-blind randomized controlled trial with resveratrol supplementation.
Topics: Acetylation; Adult; Aged; Antioxidants; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Down-Regulation; Female; Histones; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
The effects of resveratrol on markers of oxidative stress in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Adult; Aged; Antioxidants; Biomarkers; Body Weight; C-Reactive Protein; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Humans; Hydrogen Peroxide; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Placebos; Protein Carbonylation; Resveratrol; Stilbenes | 2018 |
Beneficial effects of acute trans-resveratrol supplementation in treated hypertensive patients with endothelial dysfunction.
Topics: Antioxidants; Aorta; Blood Pressure; Brachial Artery; Cholesterol, LDL; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Resveratrol; Sex Factors; Stilbenes; Vasodilation | 2018 |
Resveratrol in Patients with Minimal Hepatic Encephalopathy.
Topics: Adult; Aged; Antioxidants; Female; Hepatic Encephalopathy; Humans; Male; Middle Aged; Resveratrol; Stilbenes | 2018 |
The Oral Bioavailability of Trans-Resveratrol from a Grapevine-Shoot Extract in Healthy Humans is Significantly Increased by Micellar Solubilization.
Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Benzofurans; Biomarkers; Caco-2 Cells; Cross-Over Studies; Dietary Supplements; Enterocytes; Female; Humans; Intestinal Absorption; Male; Micelles; Phenols; Plant Extracts; Plant Shoots; Renal Elimination; Resveratrol; Single-Blind Method; Solubility; Stilbenes; Vitis | 2018 |
Effects of 90 Days of Resveratrol Supplementation on Cognitive Function in Elders: A Pilot Study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Cognition; Female; Humans; Male; Overweight; Pilot Projects; Psychomotor Performance; Resveratrol; Stilbenes | 2018 |
Efficacy and safety of resveratrol, an oral hemoglobin F-augmenting agent, in patients with beta-thalassemia intermedia.
Topics: Administration, Oral; Adolescent; Adult; Alkaloids; Benzodioxoles; beta-Thalassemia; Double-Blind Method; Female; Fetal Hemoglobin; Humans; Iran; Male; Piperidines; Polyunsaturated Alkamides; Resveratrol; Stilbenes; Treatment Outcome; Up-Regulation; Young Adult | 2018 |
Comparison of the effects of resveratrol and its derivative pterostilbene on hepatic oxidative stress and mitochondrial dysfunction in piglets challenged with diquat.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Diquat; Energy Metabolism; Gene Expression Regulation; Glutathione; Herbicides; Liver; Male; Mitochondrial Diseases; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Superoxides; Swine | 2020 |
Modulation of Energy Sensing by Leucine Synergy with Natural Sirtuin Activators: Effects on Health Span.
Topics: AMP-Activated Protein Kinases; Animals; Humans; Insulin Resistance; Leucine; Longevity; Mice, Obese; Prediabetic State; Resveratrol; Sirtuin 1; Stilbenes | 2020 |
Antioxidant Activity with Increased Endogenous Levels of Vitamin C, E and A Following Dietary Supplementation with a Combination of Glutathione and Resveratrol Precursors.
Topics: Acetylcysteine; Aged; Alanine; Antioxidants; Ascorbic Acid; Dietary Supplements; Erythrocytes; Female; Glucosides; Glutamine; Glutathione; Glycine; Humans; Ketoglutaric Acids; Male; Middle Aged; Neopterin; Oxidation-Reduction; Resveratrol; Stilbenes; Sulfhydryl Compounds; Vitamin A; Vitamin E; Vitamins | 2020 |
Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study.
Topics: Adolescent; Adult; Antioxidants; Child; Creatine Kinase; Female; Humans; Japan; Male; Motor Activity; Muscle Strength; Muscle Weakness; Muscular Dystrophies; Resveratrol; Stilbenes; Young Adult | 2020 |
Sirtuin 1 and Vascular Function in Healthy Women and Men: A Randomized Clinical Trial Comparing the Effects of Energy Restriction and Resveratrol.
Topics: Adult; Female; Glucose; Humans; Insulin; Lipids; Male; Resveratrol; Sirtuin 1; Stilbenes | 2023 |
6417 other study(ies) available for resveratrol and stilbenes
| Article | Year |
|---|---|
Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.
Topics: Anthraquinones; Emodin; Gallic Acid; Glucosides; Lipopolysaccharides; Macrophage Activation; Macrophages; Naphthalenes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Plant Extracts; Plants, Medicinal; Rheum; Stilbenes; Structure-Activity Relationship | 2000 |
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Humans; Mice; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators.
Topics: Animals; Oocytes; Orchidaceae; Patch-Clamp Techniques; Plant Extracts; Plant Roots; Plant Stems; Protein Subunits; Receptors, GABA-A; Stilbenes; Xenopus laevis | 2014 |
Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Mice; Monophenol Monooxygenase; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
An antiplatelet principle of Veratrum formosanum.
Topics: Alkaloids; Animals; Cevanes; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Platelet Aggregation Inhibitors; Rabbits; Resveratrol; Stilbenes | 1992 |
Expression of a stilbene synthase gene in Nicotiana tabacum results in synthesis of the phytoalexin resveratrol.
Topics: Acyltransferases; Arachis; Enzyme Induction; Genes, Plant; Genes, Synthetic; Immunity, Innate; Kanamycin Resistance; Nicotiana; Phytophthora; Plant Proteins; Plants, Toxic; Protoplasts; Recombinant Fusion Proteins; Resveratrol; RNA, Messenger; Stilbenes; Transformation, Genetic; Ultraviolet Rays | 1990 |
Resveratrol activity on guinea pig isolated trachea from normal and albumin-sensitized animals.
Topics: Adrenergic beta-Antagonists; Animals; Ethanolamines; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Masoprocol; Muscle Contraction; Ovalbumin; Propranolol; Quinacrine; Resveratrol; Stilbenes; Trachea | 1988 |
Antioxidant activity of resveratrol in red wine.
Topics: Antioxidants; Resveratrol; Stilbenes; Wine | 1995 |
Antiplatelet activity of synthetic and natural resveratrol in red wine.
Topics: Humans; Platelet Aggregation Inhibitors; Reference Values; Resveratrol; Stilbenes; Wine | 1995 |
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.
Topics: Arteriosclerosis; Coronary Disease; Eicosanoids; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Quercetin; Resveratrol; Stilbenes; Wine | 1995 |
[Constituents of the petroleum ether and ethyl acetate extract fractions from Dracaena cochinensis (Lour.) S.C. Chen].
Topics: Chlorobenzenes; Drugs, Chinese Herbal; Flavonoids; Resveratrol; Stilbenes | 1995 |
Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes.
Topics: Arachidonic Acid; Autoradiography; Calcimycin; Cell Degranulation; Cyclic AMP; Fatty Acids, Unsaturated; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Leukotriene C4; Lysosomes; Muramidase; Neutrophils; Plant Roots; Plants, Medicinal; Resveratrol; Stilbenes; Structure-Activity Relationship | 1995 |
Inhibition of human LDL oxidation by resveratrol.
Topics: Coronary Disease; Humans; Lipoproteins, LDL; Oxidation-Reduction; Resveratrol; Stilbenes; Wine | 1993 |
Kinase inhibitors from Polygonum cuspidatum.
Topics: Animals; Cattle; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Plants, Medicinal; Protein-Tyrosine Kinases; Rats; Resveratrol; Spectrophotometry, Ultraviolet; Stereoisomerism; Stilbenes; Thymus Gland | 1993 |
Solid phase extraction of trans-resveratrol from wines for HPLC analysis.
Topics: Cardiovascular Diseases; Chromatography, High Pressure Liquid; Humans; Italy; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Wine | 1993 |
More on antioxidant activity of resveratrol in red wine.
Topics: Aged; Antioxidants; Cell Line; Eicosanoids; Humans; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 1996 |
Method to assay the concentrations of phenolic constituents of biological interest in wines.
Topics: Antioxidants; Carbohydrate Sequence; Catechin; Chromatography, High Pressure Liquid; Molecular Sequence Data; Phenols; Platelet Aggregation Inhibitors; Quercetin; Resveratrol; Rutin; Stilbenes; Wine | 1996 |
Resveratrol content of some wines obtained from dried Valpolicella grapes: Recioto and Amarone.
Topics: Cardiovascular Diseases; Chromatography, High Pressure Liquid; Desiccation; Fruit; Mitosporic Fungi; Plant Diseases; Reproducibility of Results; Resveratrol; Stilbenes; Wine | 1996 |
Resveratrol promotes atherosclerosis in hypercholesterolemic rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Disease Models, Animal; Kidney; Lipoproteins; Liver; Male; Platelet Aggregation Inhibitors; Rabbits; Resveratrol; Stilbenes | 1996 |
Wines and grape juices as modulators of platelet aggregation in healthy human subjects.
Topics: Adult; Beverages; Blood Platelets; Fruit; Humans; In Vitro Techniques; Lipoxygenase; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Thromboxane B2; Wine | 1996 |
Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents | 1996 |
Red wine, aspirin and platelet function.
Topics: Aspirin; Blood Platelets; Cathepsin G; Cathepsins; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Serine Endopeptidases; Serotonin; Stilbenes; Thrombin; Wine | 1996 |
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Cell Differentiation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Female; Fruit; Humans; Inflammation; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Neoplasms, Experimental; Peroxidases; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Resveratrol; Skin Neoplasms; Stilbenes; Tumor Cells, Cultured | 1997 |
Antiplatelet activity of cis-resveratrol.
Topics: Collagen; Female; Humans; In Vitro Techniques; Male; Platelet Aggregation Inhibitors; Resveratrol; Stereoisomerism; Stilbenes | 1996 |
Antimutagenic effect of resveratrol against Trp-P-1.
Topics: 4-Nitroquinoline-1-oxide; Antimutagenic Agents; Carbolines; Furylfuramide; Methylnitronitrosoguanidine; Mutagenicity Tests; Mutagens; Resveratrol; Salmonella typhimurium; SOS Response, Genetics; Stilbenes | 1997 |
Plasma, urine and tissue levels of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after short-term or prolonged administration of red wine to rats.
Topics: Animals; Chromatography, High Pressure Liquid; Male; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tissue Distribution; Wine | 1996 |
Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after red wine oral administration in rats.
Topics: Administration, Oral; Animals; Biological Availability; Kidney; Liver; Male; Myocardium; Rats; Rats, Wistar; Resveratrol; ROC Curve; Stilbenes; Tissue Distribution; Wine | 1996 |
Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Death; Lipid Peroxidation; Oxidative Stress; PC12 Cells; Peroxides; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; tert-Butylhydroperoxide; Vitamin E | 1997 |
Resveratrol inhibits metal ion-dependent and independent peroxidation of porcine low-density lipoproteins.
Topics: Animals; Anticarcinogenic Agents; Copper; Dose-Response Relationship, Drug; Flavonoids; Lipid Peroxidation; Lipoproteins, LDL; Resveratrol; Stereoisomerism; Stilbenes; Swine | 1997 |
Synthesis of biologically active polyphenolic glycosides (combretastatin and resveratrol series).
Topics: Antineoplastic Agents; Bibenzyls; Cell Division; Ganglia, Spinal; Glucosides; Glycosylation; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitosis; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Tumor Cells, Cultured | 1997 |
[The virtues of grapes].
Topics: Anticarcinogenic Agents; Humans; Resveratrol; Stilbenes; Wine | 1997 |
Ethanol-induced cell death by lipid peroxidation in PC12 cells.
Topics: Animals; Antioxidants; Cell Death; Ethanol; Fatty Acids, Unsaturated; Ferrous Compounds; Fluorescent Dyes; Iron Chelating Agents; L-Lactate Dehydrogenase; Lipid Peroxidation; Neurons; PC12 Cells; Pentetic Acid; Rats; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thiobarbituric Acid Reactive Substances | 1997 |
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor.
Topics: Breast Neoplasms; Cardiovascular Diseases; Cell Division; Estradiol; Estrogens, Non-Steroidal; Female; Genes, Reporter; Humans; Isoflavones; Organ Specificity; Phytoestrogens; Plant Preparations; Receptors, Estrogen; Resveratrol; Rosales; Stilbenes; Transcriptional Activation; Tumor Cells, Cultured; Wine | 1997 |
Contents of resveratrol, piceid, and their isomers in commercially available wines made from grapes cultivated in Japan.
Topics: Chromatography, High Pressure Liquid; Glucosides; Isomerism; Japan; Reproducibility of Results; Resveratrol; Rosales; Stilbenes; Wine | 1997 |
Gas chromatographic analysis of resveratrol in plasma, lipoproteins and cells after in vitro incubations.
Topics: Animals; Calibration; Chromatography, Gas; Erythrocytes; Humans; Linear Models; Lipoproteins, LDL; Platelet Aggregation Inhibitors; Rats; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes | 1997 |
Resveratrol has no effect on lipoprotein profile and does not prevent peroxidation of serum lipids in normal rats.
Topics: Animals; Antioxidants; Female; Hydroxyl Radical; Lipid Peroxidation; Lipids; Lipoproteins; Rats; Reference Values; Resveratrol; Stilbenes | 1997 |
Resveratrol, a remarkable inhibitor of ribonucleotide reductase.
Topics: Animals; DNA, Neoplasm; Enzyme Inhibitors; Free Radicals; Humans; Mice; Nucleic Acid Synthesis Inhibitors; Recombinant Fusion Proteins; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tumor Cells, Cultured; Tyrosine | 1998 |
Antiproliferative effect of synthetic resveratrol on human breast epithelial cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured | 1998 |
Oxyresveratrol as the potent inhibitor on dopa oxidase activity of mushroom tyrosinase.
Topics: Basidiomycota; Enzyme Inhibitors; Levodopa; Monophenol Monooxygenase; Resveratrol; Stilbenes; Structure-Activity Relationship | 1998 |
Oxidized lipoproteins activate NF-kappaB binding activity and apoptosis in PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; Consensus Sequence; Lipoproteins, LDL; Lipoproteins, VLDL; NF-kappa B; Oxidation-Reduction; PC12 Cells; Promoter Regions, Genetic; Rats; Resveratrol; Signal Transduction; Stilbenes | 1998 |
Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles.
Topics: Animals; Cyclooxygenase Inhibitors; Male; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Resveratrol; Seminal Vesicles; Sheep; Stilbenes | 1998 |
Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells.
Topics: Actins; Animals; Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Gene Expression Regulation; Inositol Phosphates; Kupffer Cells; Liver; Male; Nitric Oxide; Phosphotyrosine; Quercetin; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 1998 |
Interaction of transresveratrol with plasma lipoproteins.
Topics: Analysis of Variance; Animals; Antioxidants; Fatty Acids, Unsaturated; Lipoproteins; Protein Binding; Resveratrol; Serum Albumin, Bovine; Stilbenes; Swine; Thiobarbituric Acid Reactive Substances | 1998 |
Evaluation of kinetic parameters of natural phytoalexin in resveratrol orally administered in wine to rats.
Topics: Administration, Oral; Animals; Biological Availability; Evaluation Studies as Topic; Male; Metabolic Clearance Rate; Phytoalexins; Plant Extracts; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Wine | 1998 |
Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte function.
Topics: Blood Platelets; Calcium; Cell Aggregation; Cell Survival; Cytoplasmic Granules; Enzyme Inhibitors; Flow Cytometry; Humans; In Vitro Techniques; Lipoxygenase; Neutrophils; Phosphorylation; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; Signal Transduction; Stilbenes; Tyrosine | 1998 |
Resveratrol, a phytoestrogen found in red wine. A possible explanation for the conundrum of the 'French paradox'?
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Breast Neoplasms; Estrogens, Non-Steroidal; Female; France; Humans; Isoflavones; Mammary Neoplasms, Experimental; Mice; Phytoestrogens; Plant Preparations; Plants; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 1998 |
Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells.
Topics: Antibodies, Monoclonal; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Neoplasm; Fas Ligand Protein; fas Receptor; Female; HL-60 Cells; Humans; Immunoglobulin G; Immunoglobulin kappa-Chains; Lymphocytes; Membrane Glycoproteins; Membrane Lipids; Neoplasm Proteins; Phosphatidylserines; Resveratrol; Rosales; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 1998 |
Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Breast; Cells, Cultured; Cyclooxygenase 2; Enzyme Induction; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Isoenzymes; Membrane Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Resveratrol arrests the cell division cycle at S/G2 phase transition.
Topics: Anticarcinogenic Agents; Cell Differentiation; Cell Division; DNA Replication; G2 Phase; HL-60 Cells; Humans; Resveratrol; S Phase; Stilbenes | 1998 |
Biotransformation of resveratrol to piceid by Bacillus cereus.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Bacillus cereus; Biotransformation; Enzyme Inhibitors; Glucosides; Models, Biological; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 1998 |
Paradoxical effects of resveratrol on the two prostaglandin H synthases.
Topics: Animals; Arachidonic Acid; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Enzyme Activation; Female; Indomethacin; Isoenzymes; Male; Oxidation-Reduction; Phenol; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Prostaglandins H; Resveratrol; Sheep; Stilbenes | 1998 |
Plasma and tissue resveratrol concentrations and pharmacological activity.
Topics: Animals; Humans; Male; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Resveratrol; Stilbenes; Time Factors; Wine | 1998 |
Activity in vitro of resveratrol on granulocyte and monocyte adhesion to endothelium.
Topics: Antioxidants; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Granulocytes; Humans; Intercellular Adhesion Molecule-1; Lipopolysaccharides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Protein-Tyrosine Kinases; Resveratrol; Saphenous Vein; Stilbenes; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 1998 |
Phytoalexin resveratrol (3-4'-5-trihydroxystilbene) modulates granulocyte and monocyte endothelial adhesion.
Topics: Antibodies, Monoclonal; Cell Adhesion; Cell Line; Endothelium, Vascular; Granulocytes; Humans; Monocytes; Platelet Aggregation Inhibitors; Resveratrol; Saphenous Vein; Stilbenes; U937 Cells; Vascular Cell Adhesion Molecule-1 | 1998 |
Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; Cytosol; Humans; Liver Neoplasms; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 1998 |
Resveratrol as a new type of DNA-cleaving agent.
Topics: Antineoplastic Agents, Phytogenic; Copper; DNA; DNA Damage; Hydroxyl Radical; Resveratrol; Stilbenes | 1998 |
Is resveratrol an estrogen agonist in growing rats?
Topics: Administration, Oral; Animals; Body Weight; Cholesterol; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Growth; Organ Size; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Uterus; Weaning | 1999 |
Resveratrol stimulates the proliferation and differentiation of osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Drug Interactions; Estrogen Antagonists; Estrogens, Non-Steroidal; Isoflavones; Mice; Mitogens; Osteoblasts; Phytoestrogens; Plant Preparations; Procollagen-Proline Dioxygenase; Resveratrol; Stilbenes; Tamoxifen | 1998 |
Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumour model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; Flow Cytometry; Liver Neoplasms, Experimental; Rats; Resveratrol; Stilbenes; Wine | 1999 |
Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine.
Topics: Alcohol Drinking; Cardiovascular Physiological Phenomena; Cells, Cultured; DNA; Endothelium, Vascular; Flavonoids; Humans; Phenols; Polymers; Polyphenols; Resveratrol; RNA, Messenger; Stilbenes; Thromboplastin; Transcription Factors; Transcription, Genetic; Wine | 1999 |
Determination of trans-resveratrol in plasma by HPLC.
Topics: Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Humans; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Resveratrol; Stereoisomerism; Stilbenes | 1999 |
Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production.
Topics: Adult; Animals; Antioxidants; Cell Line; Dose-Response Relationship, Drug; Humans; Luminescent Measurements; Mice; Monocytes; Neutrophils; Reactive Oxygen Species; Resveratrol; Stilbenes; Zymosan | 1999 |
Stability of resveratrol over time and in the various stages of grape transformation.
Topics: Antioxidants; Drug Stability; Fermentation; Food Handling; Resveratrol; Rosales; Stilbenes; Time Factors | 1998 |
Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Epidermal Cells; Mice; Resveratrol; Stilbenes; Transcriptional Activation; Tumor Suppressor Protein p53 | 1999 |
Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Cytokines; Gene Expression Regulation; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Quercetin; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha; Wine | 1999 |
Suppression of nitric oxide synthase and the down-regulation of the activation of NFkappaB in macrophages by resveratrol.
Topics: Animals; Cell Line; DNA-Binding Proteins; Down-Regulation; Enzyme Inhibitors; Flavonoids; Gene Expression; Gene Expression Regulation, Enzymologic; Lipopolysaccharides; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nuclear Proteins; Phosphorylation; Resveratrol; RNA, Messenger; Stilbenes | 1999 |
Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Division; Cisplatin; DNA, Neoplasm; Dose-Response Relationship, Drug; Humans; Indomethacin; Quercetin; Resveratrol; Stilbenes; Tongue Neoplasms; Tumor Cells, Cultured | 1999 |
Relaxant effect of trans-resveratrol on isolated porcine coronary arteries.
Topics: Animals; Coronary Vessels; Endothelium, Vascular; Fluorides; Histamine; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Channel Blockers; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes; Swine; Tetraethylammonium Compounds; Vasodilation; Vasodilator Agents | 1999 |
Determination of trans-resveratrol in human plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Reference Standards; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stilbenes | 1999 |
Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Division; Culture Media; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Receptor, IGF Type 1; Resveratrol; RNA, Messenger; Rosales; Stilbenes; Transcriptional Activation; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1999 |
Anti-allergic action of resveratrol and related hydroxystilbenes.
Topics: Anti-Allergic Agents; Cell Line; Resveratrol; Stilbenes | 1999 |
Resveratrol-induced activation of the mitogen-activated protein kinases, ERK1 and ERK2, in human neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neuroblastoma; Osmolar Concentration; Phosphorylation; Resveratrol; Stilbenes; Time Factors; Tretinoin; Tumor Cells, Cultured | 1999 |
Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines.
Topics: Adenocarcinoma; Apoptosis; Cell Cycle; Cell Division; Flow Cytometry; G1 Phase; Gene Expression Regulation; Growth Inhibitors; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured | 1999 |
Resveratrol inhibits MAPK activity and nuclear translocation in coronary artery smooth muscle: reversal of endothelin-1 stimulatory effects.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Inhibitors; Muscle, Smooth, Vascular; Phosphorylation; Resveratrol; Stilbenes; Swine; Tyrosine | 1999 |
Extract of wine phenolics improves aortic biomechanical properties in stroke-prone spontaneously hypertensive rats (SHRSP).
Topics: Animals; Aorta; Biomechanical Phenomena; Diet; Endothelium, Vascular; Male; Muscle Relaxation; Phenols; Rats; Rats, Inbred SHR; Resveratrol; Rosales; Stilbenes; Tea; Wine | 1999 |
Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2.
Topics: Animals; Anticarcinogenic Agents; Cattle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Endothelium, Vascular; G2 Phase; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pulmonary Artery; Resveratrol; S Phase; Stilbenes; Tumor Suppressor Protein p53 | 1999 |
The Na+/H+ exchanger modulates the fibrogenic effect of oxidative stress in rat hepatic stellate cells.
Topics: Animals; Antioxidants; Carcinogens; Cell Cycle; Cell Division; Cells, Cultured; Collagen; Culture Media; Ferric Compounds; Fluoresceins; Fluorescent Dyes; Kinetics; Liver; Liver Cirrhosis, Experimental; Malondialdehyde; Nitrilotriacetic Acid; Oxidative Stress; Rats; Resveratrol; Sodium-Hydrogen Exchangers; Stilbenes; Thiobarbituric Acid Reactive Substances | 1999 |
Recent progress in research on wine and its components and their favorable effects on health.
Topics: Health; Humans; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 1999 |
Cancer chemopreventive activity of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Benzidines; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Mice; Mutagenicity Tests; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidases; Phenylbutazone; Prostaglandin-Endoperoxide Synthases; Resveratrol; Salmonella typhimurium; Stilbenes | 1999 |
Effect of resveratrol and some other natural compounds on tyrosine kinase activity and on cytolysis.
Topics: Anti-Infective Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Male; Phytoalexins; Placenta; Plant Extracts; Prostatic Hyperplasia; Protein-Tyrosine Kinases; Reactive Oxygen Species; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Time Factors; Wine | 1999 |
Effects of resveratrol on the rat brain respiratory chain.
Topics: Adenosine Triphosphatases; Animals; Antioxidants; Brain; Citric Acid Cycle; Electron Transport; Electron Transport Complex III; Enzyme Inhibitors; Free Radical Scavengers; In Vitro Techniques; Male; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Rats; Rats, Wistar; Resveratrol; Stilbenes | 1999 |
Stimulation of endogenous adenosine release by oral administration of quercetin and resveratrol in man.
Topics: Adenosine; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Humans; Male; Platelet Aggregation Inhibitors; Quercetin; Resveratrol; Stilbenes; Time Factors | 1999 |
Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Female; Interleukin-6; Ion Transport; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Resveratrol; Stilbenes; Thymus Gland | 1999 |
Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzo(a)pyrene; Butylated Hydroxyanisole; Carotenoids; Curcumin; Female; Inositol; Lung Neoplasms; Lycopene; Mice; Mice, Inbred A; Nitrosamines; Resveratrol; Stilbenes; Umbelliferones | 1999 |
Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Female; Gene Expression; Genes, fos; Genes, jun; Genes, myc; Glutathione; Glutathione Reductase; Hydrogen Peroxide; Isoenzymes; Membrane Proteins; Mice; Oxidative Stress; Peroxidase; Prostaglandin-Endoperoxide Synthases; Resveratrol; RNA, Messenger; Skin; Stilbenes; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 1998 |
Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Bromates; Carcinogens; Cyclic N-Oxides; DNA Damage; Kidney; Male; Melatonin; Nitrogen Oxides; Organ Size; Rats; Rats, Wistar; Resveratrol; Spin Labels; Stilbenes; Vitamin E | 1999 |
Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Cycle; Chemoprevention; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; Resveratrol; Stilbenes; Transfection | 1999 |
Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids.
Topics: Amidines; Animals; Anthocyanins; Antioxidants; Binding, Competitive; Catechin; CHO Cells; Cholesterol Esters; Copper; Cricetinae; Endocytosis; Fatty Acids, Unsaturated; Flavonoids; Lipid Peroxidation; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Phenols; Phospholipids; Polymers; Proanthocyanidins; Receptors, LDL; Resveratrol; Stilbenes; Swine; Wine | 1999 |
Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells.
Topics: Anticarcinogenic Agents; Antioxidants; Apoptosis; Cell Division; Cell Nucleus; Cell Survival; DNA; DNA Fragmentation; Electrophoresis, Agar Gel; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Time Factors | 1999 |
Resveratrol inhibits copper ion-induced and azo compound-initiated oxidative modification of human low density lipoprotein.
Topics: Amidines; Azo Compounds; Copper; Electrophoresis, Agar Gel; Free Radical Scavengers; Humans; Lipoproteins, LDL; Malondialdehyde; Oxidation-Reduction; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Time Factors | 1999 |
Piceatannol, a stilbene phytochemical, inhibits mitochondrial F0F1-ATPase activity by targeting the F1 complex.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain; Cerebral Cortex; Enzyme Inhibitors; Female; In Vitro Techniques; Mitochondria; Mitochondria, Liver; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes; Swine | 1999 |
Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Topics: Acyltransferases; Amino Acid Sequence; Cerulenin; Chalcone; Crystallography, X-Ray; Flavanones; Flavonoids; Models, Molecular; Molecular Sequence Data; Mutagenesis; Plants; Protein Conformation; Resveratrol; Sequence Homology, Amino Acid; Stilbenes | 1999 |
The red wine antioxidant resveratrol protects isolated rat hearts from ischemia reperfusion injury.
Topics: Animals; Antioxidants; Free Radicals; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Peroxides; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wine | 1999 |
Resveratrol is a selective human cytochrome P450 1A1 inhibitor.
Topics: Cell Membrane; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Escherichia coli; Gene Expression; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Resveratrol; Stilbenes | 1999 |
Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity.
Topics: Apoptosis; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Humans; K562 Cells; Lipoxygenase; Lipoxygenase Inhibitors; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes | 1999 |
Suppression of mitogenesis and regulation of cell cycle traverse by resveratrol in cultured smooth muscle cells.
Topics: Animals; Antioxidants; Aorta; Cattle; Cell Cycle; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Resveratrol; Stilbenes; Thymidine | 1999 |
Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cytochrome P-450 CYP1A1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Humans; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Tumor Cells, Cultured | 1999 |
Resveratrol has antagonist activity on the aryl hydrocarbon receptor: implications for prevention of dioxin toxicity.
Topics: Anticarcinogenic Agents; Biological Transport; Cell Nucleus; Environmental Pollutants; Gene Expression Regulation; Humans; Ligands; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets.
Topics: Adult; Barium; Blood Platelets; Calcium; Calcium Channel Blockers; Calcium Channels; Egtazic Acid; Estrogens, Non-Steroidal; Genistein; Humans; Inhibitory Concentration 50; Isoflavones; Phytoestrogens; Plant Preparations; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Thapsigargin; Thrombin; Time Factors | 1999 |
"Soybean" in a Haystack? pinpointing an anti-cancer effect.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Colorectal Neoplasms; Garlic; Glycine max; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Resveratrol; Selenium; Stilbenes; Tea | 1999 |
Identification and measurement of resveratrol and formaldehyde in parts of white and blue grape berries.
Topics: Chromatography, High Pressure Liquid; Formaldehyde; Resveratrol; Rosales; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Stilbenes | 1998 |
Resveratrol preferentially inhibits protein kinase C-catalyzed phosphorylation of a cofactor-independent, arginine-rich protein substrate by a novel mechanism.
Topics: Animals; Arginine; Brain; Catalysis; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Kinetics; Phosphatidylserines; Phosphorylation; Protamines; Protein Kinase C; Rats; Resveratrol; Stilbenes; Substrate Specificity | 1999 |
Resveratrol pretreatment desensitizes AHTO-7 human osteoblasts to growth stimulation in response to carcinoma cell supernatants.
Topics: Alkaline Phosphatase; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma, Renal Cell; Cell Differentiation; Cell Line; Culture Media, Conditioned; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Kidney Neoplasms; Lung; Male; Osteoblasts; Pancreatic Neoplasms; Phytoestrogens; Plant Preparations; Prostatic Neoplasms; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 1999 |
Resveratrol inhibition of herpes simplex virus replication.
Topics: Animals; Antiviral Agents; Cell Cycle; Cell Line; Chlorocebus aethiops; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Immediate-Early Proteins; Mice; Resveratrol; Stilbenes; Vero Cells; Virus Latency; Virus Replication | 1999 |
Capillary electrophoretic determination of resveratrol in wines.
Topics: Antioxidants; Electrophoresis, Capillary; Isomerism; Resveratrol; Sensitivity and Specificity; Stilbenes; Wine | 1999 |
Evaluation of resveratrol derivatives as potential antioxidants and identification of a reaction product of resveratrol and 2, 2-diphenyl-1-picryhydrazyl radical.
Topics: Antioxidants; Bepridil; Biphenyl Compounds; Free Radical Scavengers; Free Radicals; Humans; Indicators and Reagents; Picrates; Resveratrol; Rosales; Stilbenes | 1999 |
Resveratrol and red wine consumption.
Topics: Administration, Oral; Animals; Bone Density; Cholesterol, HDL; Estrogens, Non-Steroidal; Female; Humans; Isoflavones; Ovariectomy; Phytoestrogens; Plant Preparations; Protective Agents; Rats; Receptors, Estrogen; Resveratrol; Stilbenes; Tumor Cells, Cultured; Uterus; Wine | 1999 |
Simultaneous determination of cis- and trans-resveratrol in wines by capillary zone electrophoresis.
Topics: Anticarcinogenic Agents; Electrophoresis, Capillary; Humans; Resveratrol; Stilbenes; Wine | 1999 |
trans-resveratrol content in commercial peanuts and peanut products.
Topics: Arachis; Chromatography, High Pressure Liquid; Food Handling; Resveratrol; Stilbenes | 1999 |
Piceid, the major resveratrol derivative in grape juices.
Topics: Beverages; Glucosides; Molecular Structure; Platelet Aggregation Inhibitors; Resveratrol; Rosales; Species Specificity; Stereoisomerism; Stilbenes | 1999 |
Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives.
Topics: Acetates; Biopolymers; Cell Division; Drug Screening Assays, Antitumor; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured | 1999 |
Benefits of the grape.
Topics: Antioxidants; Heart Diseases; Humans; Male; Neoplasms; Resveratrol; Rosales; Stilbenes; Wine | 1999 |
Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Gastric Mucosa; Gastrins; Gene Expression Regulation, Enzymologic; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Time Factors | 1999 |
The cancer chemopreventive agent resveratrol is incorporated into model membranes and inhibits protein kinase C alpha activity.
Topics: Acrylamide; Animals; Anticarcinogenic Agents; Calorimetry, Differential Scanning; Diffusion; Enzyme Activation; Fluorescence; Inhibitory Concentration 50; Isoenzymes; Liposomes; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membranes, Artificial; Micelles; Octoxynol; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Protein Kinase C; Protein Kinase C-alpha; Resveratrol; Stilbenes; Temperature; Thermodynamics | 1999 |
Resveratrol inhibits the expression and function of the androgen receptor in LNCaP prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Nuclear Receptor Coactivators; Oncogene Proteins; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Resveratrol; RNA, Messenger; Stilbenes; Tissue Kallikreins; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1999 |
Resveratrol is a potent inhibitor of the dioxygenase activity of lipoxygenase.
Topics: Antioxidants; Humans; Lipoxygenase Inhibitors; Resveratrol; Rosales; Stilbenes | 1999 |
Occurrence of resveratrol and pterostilbene in age-old darakchasava, an ayurvedic medicine from India.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Chromatography, High Pressure Liquid; Hypoglycemic Agents; India; Medicine, Ayurvedic; Phenols; Plant Extracts; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 1999 |
Dimerization of resveratrol by the grapevine pathogen Botrytis cinerea.
Topics: Animals; Biotransformation; Botrytis; Chlorocebus aethiops; Cyclooxygenase Inhibitors; Dimerization; HIV-1; Humans; Resveratrol; Rosales; Stilbenes; Vero Cells | 2000 |
Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin.
Topics: Animals; Antioxidants; Blood Pressure; Coronary Vessels; Emodin; Fluoresceins; Free Radical Scavengers; Gamma Rays; Hydroxyl Radical; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Oxidative Stress; Peroxides; Polygonaceae; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2000 |
Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.
Topics: Antineoplastic Agents, Phytogenic; Breast; Cell Line; Cyclooxygenase 2; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Transcription, Genetic | 1999 |
Myocardial protection with red wine extract.
Topics: Animals; Antioxidants; Blood Pressure; Drug Interactions; Ethanol; Free Radical Scavengers; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Contraction; Myocardial Infarction; Perfusion; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Time Factors; Wine | 2000 |
Isolation and identification of stilbenes in two varieties of Polygonum cuspidatum.
Topics: Chromatography, High Pressure Liquid; Glucosides; Magnetic Resonance Spectroscopy; Plant Roots; Polygonaceae; Resveratrol; Stilbenes | 2000 |
Estrogenic/antiestrogenic and scavenging properties of (E)- and (Z)-resveratrol.
Topics: Cell Division; Computer Simulation; Estradiol Congeners; Estrogen Antagonists; Free Radical Scavengers; Genes, Reporter; Humans; Iron; Luciferases; Oxidation-Reduction; Receptors, Estrogen; Resveratrol; Stereoisomerism; Stilbenes; Tumor Cells, Cultured; Vitellogenins | 2000 |
Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Kainic Acid; Male; Neuroprotective Agents; Olfactory Pathways; Rats; Rats, Wistar; Resveratrol; Stilbenes; Wine | 2000 |
In vitro response of human gingival epithelial S-G cells to resveratrol.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Count; Cell Division; Cell Line; Cell Survival; Coloring Agents; Cyclophosphamide; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Fibroblasts; Gingiva; Humans; Indicators and Reagents; Keratinocytes; Neutral Red; Oxazines; Resveratrol; Stilbenes; Tongue Neoplasms; Xanthenes | 2000 |
Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase 2; Flavonoids; Hydrogen Peroxide; In Vitro Techniques; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Phenols; Polymers; Polyphenols; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2000 |
Deactivation of cultured human liver myofibroblasts by trans-resveratrol, a grapevine-derived polyphenol.
Topics: Actins; Antioxidants; Cell Division; Cell Movement; Cells, Cultured; Enzyme Activation; Fibroblasts; Gene Expression; Humans; Liver; Matrix Metalloproteinase 2; Microscopy, Electron; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Procollagen; Resveratrol; RNA, Messenger; Stem Cells; Stilbenes | 2000 |
Resveratrol selectively inhibits leukemia cells: a prospective agent for ex vivo bone marrow purging.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Marrow Purging; Bone Marrow Transplantation; Cell Division; DNA Fragmentation; Dose-Response Relationship, Drug; Graft Survival; HL-60 Cells; Humans; Leukemia, Experimental; Male; Mice; Mice, Inbred C3H; Resveratrol; Stilbenes; Tumor Cells, Cultured; U937 Cells; Whole-Body Irradiation | 2000 |
Rational design of potent human transthyretin amyloid disease inhibitors.
Topics: Amino Acid Sequence; Amyloid Neuropathies; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Binding Sites; Cardiomyopathies; Crystallography, X-Ray; Dicarboxylic Acids; Diclofenac; Drug Design; Flurbiprofen; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; ortho-Aminobenzoates; Oxazines; Prealbumin; Protein Structure, Quaternary; Resveratrol; Stilbenes; Structure-Activity Relationship; Thermodynamics | 2000 |
Resveratrol, a natural stilbene in grapes and wine, enhances intraphagocytosis in human promonocytes: a co-factor in antiinflammatory and anticancer chemopreventive activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Candida albicans; Cell Division; Humans; Monocytes; Phagocytosis; Phosphatidylserines; Resveratrol; Rosales; Stilbenes; U937 Cells; Wine | 1999 |
Resveratrol-type oligostilbenes from Iris clarkei antagonize 20-hydroxyecdysone action in the Drosophila melanogaster B(II) cell line.
Topics: Animals; Benzofurans; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drosophila melanogaster; Ecdysterone; Flavonoids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plants; Radioimmunoassay; Resveratrol; Seeds; Stilbenes | 2000 |
Occurrence of resveratrol in edible peanuts.
Topics: Arachis; Chromatography, High Pressure Liquid; Platelet Aggregation Inhibitors; Resveratrol; Seeds; Spain; Stilbenes; Virginia; Wine | 2000 |
Resveratrol induces vasorelaxation of mesenteric and uterine arteries from female guinea-pigs.
Topics: Acetylcholine; Animals; Arteries; Calcimycin; Enzyme Inhibitors; Female; Guinea Pigs; Indomethacin; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Platelet Aggregation Inhibitors; Potassium Chloride; Resveratrol; Stilbenes; Uterus; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2000 |
Constitutive accumulation of a resveratrol-glucoside in transgenic alfalfa increases resistance to Phoma medicaginis.
Topics: Acyltransferases; Ascomycota; Base Sequence; Chromatography, High Pressure Liquid; DNA Primers; Glucosides; Magnetic Resonance Spectroscopy; Medicago sativa; Plants, Genetically Modified; Resveratrol; RNA, Messenger; Stilbenes | 2000 |
Liquid chromatography with multichannel electrochemical detection for the determination of trans-resveratrol in rat blood utilizing an automated blood sampling device.
Topics: Animals; Automation; Calibration; Chromatography, Liquid; Platelet Aggregation Inhibitors; Quality Control; Rats; Reference Standards; Reproducibility of Results; Resveratrol; Stereoisomerism; Stilbenes | 2000 |
DNA breakage by resveratrol and Cu(II): reaction mechanism and bacteriophage inactivation.
Topics: Animals; Anticarcinogenic Agents; Bacteriophage lambda; Cattle; Copper; DNA; DNA Damage; Dose-Response Relationship, Drug; Endoribonucleases; Formazans; Free Radical Scavengers; Ions; Neoplasms; Phenanthrolines; Reactive Oxygen Species; Resveratrol; Spectrophotometry; Stilbenes; Thymus Gland; Time Factors; Ultraviolet Rays | 2000 |
Inhibitory effect of resveratrol on free radical generation in blood platelets.
Topics: Animals; Antioxidants; Blood Platelets; Free Radicals; Humans; Hydrogen Peroxide; In Vitro Techniques; Luminescent Measurements; Oxygen; Reactive Oxygen Species; Resveratrol; Singlet Oxygen; Stilbenes; Superoxides; Swine; Thrombin | 1999 |
Resveratrol inhibition of lipid peroxidation.
Topics: Antioxidants; Ascorbic Acid; Bepridil; Biphenyl Compounds; Chromans; Free Radical Scavengers; Free Radicals; In Vitro Techniques; Iron; Lipid Peroxidation; Liposomes; Picrates; Resveratrol; Stilbenes; Vitamin E | 2000 |
Class A scavenger receptor up-regulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation.
Topics: Calcium; Cell Differentiation; Cell Line; Cell Nucleus; Culture Media, Conditioned; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Kinetics; Lipoproteins, LDL; Macrophages; Membrane Proteins; Mitogen-Activated Protein Kinases; Monocytes; Muscle, Smooth; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Receptors, Immunologic; Receptors, Scavenger; Resveratrol; RNA, Messenger; Scavenger Receptors, Class A; Stilbenes; Sulfonamides; Transcription, Genetic; Transfection; Up-Regulation | 2000 |
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation.
Topics: Apoptosis; Biological Transport; Caspase Inhibitors; Cell Line; Cell Nucleus; Ceramides; Cytotoxicity, Immunologic; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Lipid Peroxidation; Lipopolysaccharides; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2000 |
Oligostilbenoids in stem bark of Vatica rassak.
Topics: Benzofurans; Glucosides; Plant Extracts; Plant Stems; Resveratrol; Stilbenes; Trees | 2000 |
Resveratrol induces Fas signalling-independent apoptosis in THP-1 human monocytic leukaemia cells.
Topics: Analysis of Variance; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line; Fas Ligand Protein; fas Receptor; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoblotting; Jurkat Cells; Leukemia, Monocytic, Acute; Membrane Glycoproteins; Resveratrol; Stilbenes | 2000 |
trans-resveratrol protects embryonic mesencephalic cells from tert-butyl hydroperoxide: electron paramagnetic resonance spin trapping evidence for a radical scavenging mechanism.
Topics: Animals; Antioxidants; Coumarins; Electron Spin Resonance Spectroscopy; Female; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; L-Lactate Dehydrogenase; Mesencephalon; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Spin Labels; Stilbenes; tert-Butylhydroperoxide | 2000 |
Red wine may reduce oral cancer risks.
Topics: Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Division; Humans; Mouth Neoplasms; Quercetin; Resveratrol; Stilbenes; Wine | 2000 |
Potent inhibitory action of red wine polyphenols on human breast cancer cells.
Topics: Antioxidants; Breast Neoplasms; Catechin; Cell Division; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Estradiol; Female; Flavonoids; Flow Cytometry; Humans; Hydrogen Peroxide; Phenols; Polymers; Progesterone; Reactive Oxygen Species; Receptors, Steroid; Resveratrol; Stilbenes; Time Factors; Tumor Cells, Cultured; Wine | 2000 |
Antioxidative and prooxidative action of stilbene derivatives.
Topics: Animals; Antioxidants; Catechin; Chromans; Diethylstilbestrol; DNA Damage; Ferric Compounds; Free Radical Scavengers; Lipid Peroxidation; Microsomes, Liver; Oxidation-Reduction; Phycoerythrin; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2000 |
Resveratrol modulates arachidonic acid release, prostaglandin synthesis, and 3T6 fibroblast growth.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arachidonic Acid; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Fibroblasts; Mice; Phospholipases A; Platelet-Derived Growth Factor; Prostaglandins; Reactive Oxygen Species; Resveratrol; Stilbenes | 2000 |
Resveratrol is absorbed in the small intestine as resveratrol glucuronide.
Topics: Animals; Antioxidants; Biological Transport, Active; Glucuronides; Ileum; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Jejunum; Kinetics; Male; Perfusion; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2000 |
Inhibition of mitochondrial proton F0F1-ATPase/ATP synthase by polyphenolic phytochemicals.
Topics: Animals; Enzyme Inhibitors; Female; Flavonoids; Genistein; Mitochondria; Phenols; Polymers; Proton-Translocating ATPases; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes | 2000 |
Resveratrol attenuates ovariectomy-induced hypertension and bone loss in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Bone Density; Disease Models, Animal; Female; Femur; Hypertension; Osteoporosis; Ovariectomy; Rats; Rats, Inbred SHR; Resveratrol; Stilbenes | 2000 |
Assessment of resveratrol bioavailability in the perfused small intestine of the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chromatography, High Pressure Liquid; Electrochemistry; In Vitro Techniques; Intestine, Small; Male; Mass Spectrometry; Perfusion; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resveratrol; Solvents; Stilbenes | 2000 |
Resveratrol inhibits AGEs-induced proliferation and collagen synthesis activity in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fulvestrant; Glycation End Products, Advanced; Male; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Procollagen-Proline Dioxygenase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Estrogen; Resveratrol; Stilbenes; Stroke; Time Factors; Transforming Growth Factor beta | 2000 |
Chemopreventive properties of trans-resveratrol are associated with inhibition of activation of the IkappaB kinase.
Topics: Anticarcinogenic Agents; Cell Line; Chloramphenicol O-Acetyltransferase; Enzyme Activation; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; I-kappa B Kinase; Luciferases; NF-kappa B; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Transfection; Tumor Necrosis Factor-alpha; U937 Cells | 2000 |
Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; bcl-2-Associated X Protein; Carcinogens; Cell Division; Colon; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Growth Inhibitors; Intestinal Mucosa; Male; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Rectum; Resveratrol; Stilbenes | 2000 |
Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential.
Topics: Animals; Anticarcinogenic Agents; Apigenin; Catechin; Cell Division; Curcumin; Female; Flavonoids; Growth Inhibitors; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Transplantation; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2000 |
Stilbenoids isolated from stem bark of Shorea hemsleyana.
Topics: Magnetic Resonance Spectroscopy; Malvaceae; Plant Stems; Resveratrol; Stilbenes | 2000 |
Sulphation of resveratrol, a natural product present in grapes and wine, in the human liver and duodenum.
Topics: Adult; Aged; Biological Availability; Duodenum; Humans; Kinetics; Liver; Mefenamic Acid; Middle Aged; Molecular Structure; Phosphoadenosine Phosphosulfate; Quercetin; Resveratrol; Rosales; Salicylic Acid; Stilbenes; Sulfates; Sulfotransferases; Wine | 2000 |
Resveratrol inhibits the growth of Helicobacter pylori in vitro.
Topics: Antioxidants; Helicobacter pylori; Humans; Microbial Sensitivity Tests; Resveratrol; Stilbenes | 2000 |
Dose-dependent effect of resveratrol on proliferation and apoptosis in endothelial and tumor cell cultures.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Humans; Mitosis; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2000 |
Does resveratrol induce pharmacological preconditioning?
Topics: Adenosine; Animals; Antioxidants; Cardiovascular Physiological Phenomena; Heart; Ischemic Preconditioning, Myocardial; Male; Muscle Contraction; Myocardial Infarction; Myocardial Ischemia; Myocardium; Phosphates; Phosphorylation; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow; Reperfusion Injury; Resveratrol; Stilbenes | 2000 |
Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Cycle; Cell Division; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Resveratrol; Rosales; Stilbenes; Wine | 2000 |
Cardioprotective effect of resveratrol, a natural antioxidant derived from grapes.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Chi-Square Distribution; Free Radical Scavengers; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Statistics, Nonparametric; Stilbenes; Tachycardia, Ventricular; Ventricular Fibrillation | 2000 |
Evidence for catalytic cysteine-histidine dyad in chalcone synthase.
Topics: Acyltransferases; Amino Acid Substitution; Binding Sites; Catalysis; Cysteine; Diethyl Pyrocarbonate; Enzyme Inhibitors; Escherichia coli; Flavanones; Flavonoids; Histidine; Hydrogen-Ion Concentration; Iodoacetamide; Malonyl Coenzyme A; Mutagenesis, Site-Directed; Plants; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2000 |
Resveratrol reverses tumor-promoter-induced inhibition of gap-junctional intercellular communication.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Cell Communication; Cells, Cultured; Connexin 43; DDT; Dose-Response Relationship, Drug; Epithelial Cells; Gap Junctions; Isoquinolines; Liver; Microinjections; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Resveratrol; RNA, Messenger; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Resveratrol content in wines and musts from the south of Spain.
Topics: Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Climate; Filtration; Resveratrol; Rosales; Spain; Spectrophotometry, Ultraviolet; Stilbenes; Temperature; Wine | 2000 |
Resveratrol decreases early signaling events in washed platelets but has little effect on platelet in whole blood.
Topics: Adult; Blood Platelets; Humans; MAP Kinase Signaling System; Platelet Aggregation; Platelet Aggregation Inhibitors; Plateletpheresis; Resveratrol; Signal Transduction; Stilbenes | 2000 |
Effects of resveratrol on the autophosphorylation of phorbol ester-responsive protein kinases: inhibition of protein kinase D but not protein kinase C isozyme autophosphorylation.
Topics: Anticarcinogenic Agents; Carcinogens; Dose-Response Relationship, Drug; Humans; Intercellular Signaling Peptides and Proteins; Peptides; Phorbol Esters; Phosphorylation; Protein Kinase C; Recombinant Proteins; Resveratrol; Stilbenes | 2000 |
Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta.
Topics: Animals; Cell Division; CHO Cells; Consensus Sequence; Cricetinae; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Genes, Reporter; Humans; Receptors, Estrogen; Response Elements; Resveratrol; Stilbenes; Transfection | 2000 |
Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Blood Platelets; Chromans; Platelet Adhesiveness; Resveratrol; Selenic Acid; Selenium Compounds; Sodium Selenite; Stilbenes; Swine; Vitamin E | 2000 |
Inhibition of dioxin effects on bone formation in vitro by a newly described aryl hydrocarbon receptor antagonist, resveratrol.
Topics: Alkaline Phosphatase; Animals; Biomarkers; Bone Marrow Cells; Calcification, Physiologic; Cell Culture Techniques; Cell Differentiation; Chick Embryo; Collagen; Enzyme Inhibitors; Osteogenesis; Polychlorinated Dibenzodioxins; Rats; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2000 |
The use of transgenic yeasts expressing a gene encoding a glycosyl-hydrolase as a tool to increase resveratrol content in wine.
Topics: Aspergillus niger; beta-Glucosidase; Candida; Glycoside Hydrolases; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Transgenes; Wine | 2000 |
Synergy between ethanol and grape polyphenols, quercetin, and resveratrol, in the inhibition of the inducible nitric oxide synthase pathway.
Topics: Animals; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Ethanol; Flavonoids; Gene Expression; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenols; Polymers; Quercetin; Resveratrol; Rosales; Stilbenes | 2000 |
Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Hippocampus; Lipoxygenase Inhibitors; Neuroprotective Agents; Nitric Oxide; Nitrites; Protein Kinase C; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Wine | 2000 |
Effects of trans-resveratrol on copper-dependent hydroxyl-radical formation and DNA damage: evidence for hydroxyl-radical scavenging and a novel, glutathione-sparing mechanism of action.
Topics: Antioxidants; Ascorbic Acid; Copper; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione; Humans; Hydrogen Peroxide; Hydroxyl Radical; In Vitro Techniques; Resveratrol; Stilbenes | 2000 |
Isolation and characterization of novel stilbene derivatives from Riesling wine.
Topics: Antioxidants; Dimerization; Glucosides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Chemical; Resveratrol; Stilbenes; Wine | 2000 |
Resveratrol causes arrest in the S-phase prior to Fas-independent apoptosis in CEM-C7H2 acute leukemia cells.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase Inhibitors; Caspases; Cell Separation; Dose-Response Relationship, Drug; Doxycycline; Fas Ligand Protein; fas Receptor; Flow Cytometry; Humans; Interphase; Jurkat Cells; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Recombinant Fusion Proteins; Resveratrol; S Phase; Stilbenes; Time Factors; Transfection; Transgenes; Tumor Cells, Cultured | 2000 |
Effect of postharvest ultraviolet irradiation on resveratrol and other phenolics of cv. Napoleon table grapes.
Topics: Anthocyanins; Antioxidants; Chromatography, High Pressure Liquid; Glucosides; Phenols; Resveratrol; Rosales; Stilbenes; Ultraviolet Rays | 2000 |
Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids.
Topics: Aged; Apigenin; Biological Availability; Duodenum; Female; Flavonoids; Flavonols; Fruit; Humans; Kaempferols; Kinetics; Liver; Male; Middle Aged; Quercetin; Resveratrol; Stilbenes; Substrate Specificity; Sulfates; Sulfotransferases; Vegetables; Wine | 2000 |
Structural determinants for activation and block of CFTR-mediated chloride currents by apigenin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenocarcinoma; Anesthetics, Local; Apigenin; Biological Transport; Calcium Channel Blockers; Chlorides; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Lidocaine; Lung; Lung Neoplasms; ortho-Aminobenzoates; Quinidine; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2000 |
Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumour growth and lung metastasis in Lewis lung carcinoma-bearing mice.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cattle; DNA; Drug Screening Assays, Antitumor; Endothelium, Vascular; Female; Glucosides; Humans; Mice; Mice, Inbred C57BL; Organ Size; Phytotherapy; Plants, Medicinal; Resveratrol; Ribonucleotide Reductases; Spleen; Stilbenes; Swine; T-Lymphocytes; Thymus Gland; Umbilical Veins; Wine | 2000 |
Trans-resveratrol modulates the catalytic activity and mRNA expression of the procarcinogen-activating human cytochrome P450 1B1.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Catalysis; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Humans; Oxazines; Resveratrol; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2000 |
Resveratrol inhibits interleukin-6 production in cortical mixed glial cells under hypoxia/hypoglycemia followed by reoxygenation.
Topics: Animals; Antioxidants; Cerebral Cortex; Hyperglycemia; Hypoxia; Interleukin-6; Neuroglia; NF-kappa B; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2001 |
The mechanism of resveratrol-induced vasorelaxation differs in the mesenteric resistance arteries of lean and obese rats.
Topics: Acetylcholine; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Indomethacin; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Obesity; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Synergistic inhibition of HIV-1 in activated and resting peripheral blood mononuclear cells, monocyte-derived macrophages, and selected drug-resistant isolates with nucleoside analogues combined with a natural product, resveratrol.
Topics: Cell Division; Didanosine; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Macrophages; Nucleosides; Resveratrol; Stilbenes; Virus Replication; Zalcitabine; Zidovudine | 2000 |
Resveratrol, a red wine constituent, is a mechanism-based inactivator of cytochrome P450 3A4.
Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Kinetics; Mixed Function Oxygenases; Resveratrol; Spodoptera; Stilbenes; Wine | 2000 |
Phytoestrogens attenuate oxidative DNA damage in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats.
Topics: Animals; Base Sequence; Cells, Cultured; DNA Damage; DNA Primers; Estrogens, Non-Steroidal; Genistein; Glutathione; Glutathione Peroxidase; Glycation End Products, Advanced; Hypertension; Isoflavones; Muscle, Smooth, Vascular; Oxidation-Reduction; Oxidative Stress; Phytoestrogens; Plant Preparations; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Stroke | 2000 |
Resveratrol selectively inhibits Neisseria gonorrhoeae and Neisseria meningitidis.
Topics: Bacteria; Fungi; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Neisseria meningitidis; Resveratrol; Stilbenes | 2001 |
Chemopreventive agent resveratrol, a natural product derived from grapes, reversibly inhibits progression through S and G2 phases of the cell cycle in U937 cells.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Count; Cell Cycle; Cell Cycle Proteins; Cell Division; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Humans; Resveratrol; Rosales; S Phase; Stilbenes; Time Factors; U937 Cells | 2001 |
Method for the quantitative extraction of resveratrol and piceid isomers in grape berry skins. Effect of powdery mildew on the stilbene content.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Botrytis; Glucosides; Mitosporic Fungi; Plant Diseases; Platelet Aggregation Inhibitors; Resveratrol; Rosales; Stilbenes | 2001 |
Induced cytoskeletal changes in bovine pulmonary artery endothelial cells by resveratrol and the accompanying modified responses to arterial shear stress.
Topics: Actin Cytoskeleton; Animals; Calcium Signaling; Cardiotonic Agents; Cattle; Cell Adhesion; Cell Division; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Microtubules; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein-Tyrosine Kinases; Pulmonary Artery; Resveratrol; Signal Transduction; Stilbenes; Stress, Mechanical | 2001 |
Effect of resveratrol on intimal hyperplasia after endothelial denudation in an experimental rabbit model.
Topics: Animals; Antioxidants; Cattle; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Graft Occlusion, Vascular; Hyperplasia; Iliac Artery; Male; Muscle, Smooth, Vascular; Rabbits; Resveratrol; Stilbenes; Tunica Intima | 2000 |
Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver.
Topics: Adult; Aged; Apigenin; Catechin; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Flavonols; Glucuronic Acid; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Kaempferols; Kinetics; Liver; Male; Microsomes, Liver; Middle Aged; Quercetin; Reproducibility of Results; Resveratrol; Rosales; Stilbenes; Wine | 2000 |
[Experimental study of resveratrol and flavonoids in red wine with regard to their possible hypolipemic effects].
Topics: Animals; Antioxidants; Cholesterol; Fenofibrate; Flavonoids; Hypercholesterolemia; Hypolipidemic Agents; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Wine | 2000 |
N-acetylcysteine downregulates vascular endothelial growth factor production by human keratinocytes in vitro.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Cell Culture Techniques; Cell Division; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Growth Factors; Female; Humans; Keratinocytes; Lymphokines; Quercetin; Resveratrol; Stilbenes; Thymidine; Tritium; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
High-speed counter-current chromatography separation and purification of resveratrol and piceid from Polygonum cuspidatum.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Glucosides; Isomerism; Magnetic Resonance Spectroscopy; Polygonaceae; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2001 |
Differential response of immature rat uterine tissue to ethinylestradiol and the red wine constituent resveratrol.
Topics: Animals; Body Weight; Estradiol Congeners; Estrogen Receptor alpha; Estrogens, Non-Steroidal; Ethinyl Estradiol; Female; Gene Expression; Immunohistochemistry; Organ Size; Peroxidase; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Progesterone; Resveratrol; RNA, Messenger; Sexual Maturation; Stilbenes; Uterus | 2001 |
Resveratrol decreases hyperalgesia induced by carrageenan in the rat hind paw.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Foot; Hindlimb; Hyperalgesia; Isoenzymes; Kinetics; Male; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Vocalization, Animal | 2001 |
Polyphyenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells.
Topics: Catechin; Cells, Cultured; Dactinomycin; Endothelium, Vascular; Fibrinolysis; Flavonoids; Gene Expression; Humans; Luciferases; Nucleic Acid Synthesis Inhibitors; Phenols; Polymers; Promoter Regions, Genetic; Quercetin; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tissue Plasminogen Activator; Transfection; Umbilical Veins; Urokinase-Type Plasminogen Activator | 2001 |
Resveratrol, a polyphenol found in wine, reduces ischemia reperfusion injury in rat kidneys.
Topics: Animals; Antioxidants; Ischemia; Kidney; Lipid Peroxidation; Male; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2001 |
Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line; Enzyme Activation; Epidermal Cells; Epidermis; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Resveratrol; Serine; Stilbenes; Transcriptional Activation; Tumor Suppressor Protein p53 | 2001 |
Antioxidant activity of resveratrol compared with common food additives.
Topics: Antioxidants; Dose-Response Relationship, Drug; Fatty Acids; Food Additives; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Oxidation-Reduction; Phospholipids; Resveratrol; Stilbenes | 2001 |
Both cyclooxygenase-1 and cyclooxygenase-2 mediate osteoblast response to titanium surface roughness.
Topics: Alkaline Phosphatase; Biocompatible Materials; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Isoenzymes; Materials Testing; Membrane Proteins; Nitrobenzenes; Osteoblasts; Osteocalcin; Phenotype; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Sulfonamides; Surface Properties; Titanium; Transforming Growth Factor beta | 2001 |
Investigation into the rapid effects of 17 beta-estradiol and neuroactive steroids upon beta-amyloid(25-35)-induced activation of phosphoinositide-specific phospholipase C in human platelets.
Topics: Amyloid beta-Peptides; Blood Platelets; Calcium; Estradiol; Estrogens, Non-Steroidal; Hemostatics; Homeostasis; Humans; Peptide Fragments; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Platelet Aggregation Inhibitors; Pregnanolone; Progesterone; Resveratrol; Serotonin; Spectrometry, Fluorescence; Steroids; Stilbenes; Thrombin | 2000 |
Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinase.
Topics: 3T3 Cells; Animals; Cell Fractionation; Cell Line; Cell Nucleus; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nuclear Proteins; Oligonucleotides, Antisense; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Receptors, Thyroid Hormone; Resveratrol; Serine; Stilbenes; Thyroxine; Transfection; Triiodothyronine; Tumor Suppressor Protein p53 | 2001 |
Resveratrol and other phenolics from the bark of Yucca schidigera roezl.
Topics: Flavonoids; Liliaceae; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Phenols; Plant Stems; Plants, Medicinal; Resveratrol; Spectrometry, Mass, Fast Atom Bombardment; Stilbenes | 2001 |
Inhibition of glucose and dehydroascorbic acid uptakes by resveratrol in human transformed myelocytic cells.
Topics: Animals; Cell Line, Transformed; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Dehydroascorbic Acid; Glucose; Glucose Transporter Type 1; Granulocytes; HL-60 Cells; Humans; Monosaccharide Transport Proteins; Resveratrol; Stilbenes | 2001 |
Anti-apoptotic effect of trans-resveratrol on paclitaxel-induced apoptosis in the human neuroblastoma SH-SY5Y cell line.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Caspase 7; Caspases; Humans; Neuroblastoma; Paclitaxel; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Lung carcinogenesis: resveratrol modulates the expression of genes involved in the metabolism of PAH in human bronchial epithelial cells.
Topics: Anticarcinogenic Agents; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bronchi; Cell Line, Transformed; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Epithelial Cells; Epoxide Hydrolases; Gene Expression; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; Lung Neoplasms; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Resveratrol inhibits the formation of phosphatidic acid and diglyceride in chemotactic peptide- or phorbol ester-stimulated human neutrophils.
Topics: Choline; Chromatography, Thin Layer; Diglycerides; Drug Interactions; Ethanol; Ethanolamine; Glycerophosphates; Glycerophospholipids; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphatidylcholines; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Effect of trans-resveratrol on 7-benzyloxy-4-trifluoromethylcoumarin O-dealkylation catalyzed by human recombinant CYP3A4 and CYP3A5.
Topics: Catalysis; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Inhibitors; Humans; Indicators and Reagents; Kinetics; Mixed Function Oxygenases; Recombinant Proteins; Resveratrol; Stilbenes | 2001 |
Beneficial effects of astringinin, a resveratrol analogue, on the ischemia and reperfusion damage in rat heart.
Topics: Animals; Antioxidants; Free Radical Scavengers; Heart; Hemodynamics; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide; Nitrites; Rats; Resveratrol; Stilbenes; Tachycardia, Ventricular; Ventricular Fibrillation | 2001 |
Interaction of sheep liver cytosolic aldehyde dehydrogenase with quercetin, resveratrol and diethylstilbestrol.
Topics: Aldehyde Dehydrogenase; Animals; Binding Sites; Catalytic Domain; Cytosol; Diethylstilbestrol; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liver; Models, Molecular; NAD; Protein Conformation; Quercetin; Resveratrol; Sheep; Stilbenes | 2001 |
The ABC transporter BcatrB affects the sensitivity of Botrytis cinerea to the phytoalexin resveratrol and the fungicide fenpiclonil.
Topics: Amino Acid Sequence; ATP-Binding Cassette Transporters; Botrytis; Cloning, Molecular; Molecular Sequence Data; Pyrroles; Resveratrol; Sequence Homology, Amino Acid; Stilbenes; Virulence | 2001 |
Resveratrol and piceid levels in natural and blended peanut butters.
Topics: Absorption; Arachis; Chromatography, High Pressure Liquid; Food Handling; Glucosides; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2000 |
Resveratrol and a novel tyrosinase in Carignan grape juice.
Topics: Antioxidants; Beverages; Fruit; Kinetics; Molecular Weight; Monophenol Monooxygenase; Resveratrol; Stilbenes; Substrate Specificity; Wine | 2001 |
Resveratrol inhibits human breast cancer cell growth and may mitigate the effect of linoleic acid, a potent breast cancer cell stimulator.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Cell Division; Female; Humans; Linoleic Acid; Membrane Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol.
Topics: Animals; Antioxidants; Cell Cycle; Cells, Cultured; DNA Polymerase I; DNA Replication; DNA-Binding Proteins; Humans; Lipid Peroxidation; Microsomes, Liver; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Replication Protein A; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Involvement of cyclooxygenase-derived prostaglandin E2 and nitric oxide in the protection of rat pancreas afforded by low dose of lipopolysaccharide.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ceruletide; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Indomethacin; Isoenzymes; Lactones; Lipopolysaccharides; Male; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitrobenzenes; Organ Size; Pancreas; Pancreatitis; Penicillamine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Resveratrol; S-Nitroso-N-Acetylpenicillamine; Stilbenes; Sulfonamides; Sulfones | 2001 |
Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; CDC2-CDC28 Kinases; Cell Division; Cyclin D1; Cyclin D2; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Phosphotransferases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
The effect of resveratrol on the platelet secretory process induced by endotoxin and thrombin.
Topics: Adenine Nucleotides; Animals; Blood Platelets; Blood Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Hemostatics; Lipopolysaccharides; Platelet Aggregation Inhibitors; Proteus mirabilis; Resveratrol; Stilbenes; Swine; Thrombin | 2001 |
Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Hepatocellular; Cell Division; Hypoxanthine; Liver Neoplasms; Neoplasm Invasiveness; Rats; Resveratrol; Stilbenes; Tumor Cells, Cultured; Xanthine Oxidase | 2001 |
Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Gastric Mucosa; Gastrins; Indomethacin; Interleukin-1; Isoenzymes; Lactones; Male; Meloxicam; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stomach Ulcer; Sulfonamides; Sulfones; Thiazines; Thiazoles; Tumor Necrosis Factor-alpha | 2001 |
In vivo inhibition of TNFalpha-induced vascular permeability by resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Liver; Liver Circulation; Male; Mice; Mice, Inbred BALB C; Recombinant Proteins; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2001 |
Resveratrol, a natural dietary phytoalexin, possesses similar properties to hydroxyurea towards erythroid differentiation.
Topics: Anemia, Sickle Cell; Antioxidants; Blotting, Western; Cell Differentiation; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythroid Precursor Cells; Fetal Hemoglobin; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Hemoglobins; Humans; Hydroxyurea; Leukemia, Erythroblastic, Acute; Models, Biological; Proto-Oncogene Proteins p21(ras); Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotide Reductases; Stem Cells; Stilbenes; Time Factors | 2001 |
Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice.
Topics: Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Carcinoma, Lewis Lung; CD4-CD8 Ratio; Cell Cycle; Disease Models, Animal; DNA; Female; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Organ Size; Polygonaceae; Resveratrol; Spleen; Stilbenes; Thymus Gland; Tumor Cells, Cultured | 2001 |
Measurement of trans-resveratrol, (+)-catechin, and quercetin in rat and human blood and urine by gas chromatography with mass selective detection.
Topics: Animals; Calibration; Catechin; Gas Chromatography-Mass Spectrometry; Humans; Quality Control; Quercetin; Rats; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes | 2001 |
Absorption of trans-resveratrol in rats.
Topics: Animals; Antioxidants; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2001 |
DNA oxidatively damaged by chromium(III) and H(2)O(2) is protected by the antioxidants melatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine, resveratrol and uric acid.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Chromatography, High Pressure Liquid; Chromium Compounds; Deoxyguanosine; DNA Damage; Hydrogen Peroxide; Kynuramine; Melatonin; Molecular Structure; Resveratrol; Stilbenes; Uric Acid | 2001 |
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 9; Caspases; Enzyme Activation; Fas Ligand Protein; fas Receptor; Humans; Intracellular Membranes; Leukocytes, Mononuclear; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes; Translocation, Genetic; Tumor Cells, Cultured | 2001 |
Automated solid-phase extraction for sample preparation followed by high-performance liquid chromatography with diode array and mass spectrometric detection for the analysis of resveratrol derivatives in wine.
Topics: Automation; Calibration; Chromatography, High Pressure Liquid; Mass Spectrometry; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Wine | 2001 |
Resveratrol inhibits phorbol ester and UV-induced activator protein 1 activation by interfering with mitogen-activated protein kinase pathways.
Topics: Anticarcinogenic Agents; Carcinogens; Drug Interactions; Enzyme Activation; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Estrogen; Resveratrol; src-Family Kinases; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tyrosine; Ultraviolet Rays | 2001 |
Trans-resveratrol, a grapevine-derived polyphenol, blocks hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Flavonoids; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase Kinases; Neoplasm Invasiveness; Phenols; Phosphorylation; Poly(ADP-ribose) Polymerases; Polymers; Polyphenols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Resveratrol; RNA, Messenger; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2001 |
Hopeafuran and a C-glucosyl resveratrol isolated from stem wood of Hopea utilis.
Topics: Benzofurans; Molecular Structure; Plant Stems; Resveratrol; Rosales; Spectrum Analysis; Stilbenes; Wood | 2001 |
Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation.
Topics: 2-Propanol; Animals; Antioxidants; Carbon Tetrachloride; Egg Yolk; Free Radical Scavengers; Lipid Peroxidation; Peroxides; Pulse Radiolysis; Resveratrol; Stilbenes; Time Factors | 2001 |
Ultrasensitive assay for three polyphenols (catechin, quercetin and resveratrol) and their conjugates in biological fluids utilizing gas chromatography with mass selective detection.
Topics: Calibration; Catechin; Gas Chromatography-Mass Spectrometry; Humans; Quality Control; Quercetin; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes | 2001 |
Resveratrol, a naturally occurring polyphenol, induces sister chromatid exchanges in a Chinese hamster lung (CHL) cell line.
Topics: Animals; Cell Division; Cell Line; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; Flavonoids; Lung; Mutagenicity Tests; Mutagens; Phenols; Polymers; Polyphenols; Resveratrol; Sister Chromatid Exchange; Stilbenes | 2001 |
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.
Topics: Anticarcinogenic Agents; Apoptosis; Apoptosis Inducing Factor; Biological Transport; Caspase 2; Caspase 3; Caspase 6; Caspase 9; Caspases; Cytochrome c Group; DNA; Enzyme Activation; Flavoproteins; Humans; Membrane Proteins; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 25; Resveratrol; Rosales; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2001 |
Inhibitory effect of resveratrol on proteinuria, hypoalbuminemia and hyperlipidemia in nephritic rats.
Topics: Administration, Oral; Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Basement Membrane; Blood Urea Nitrogen; Body Weight; Cholesterol; Disease Models, Animal; Eating; Glomerulonephritis; Hyperlipidemias; Hypoproteinemia; Kidney; Kidney Glomerulus; Liver; Male; Organ Size; Proteinuria; Rabbits; Rats; Rats, Wistar; Resveratrol; Stilbenes; Triglycerides | 2001 |
Novel polyketides synthesized with a higher plant stilbene synthase.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Arachis; Asteraceae; Base Sequence; DNA Primers; DNA, Complementary; Kinetics; Malonyl Coenzyme A; Molecular Sequence Data; Recombinant Proteins; Resveratrol; Sequence Alignment; Sequence Homology, Amino Acid; Stilbenes; Structure-Activity Relationship; Substrate Specificity | 2001 |
In vitro tolerance to Botrytis cinerea of grapevine 41B rootstock in transgenic plants expressing the stilbene synthase Vst1 gene under the control of a pathogen-inducible PR 10 promoter.
Topics: Acyltransferases; Botrytis; Medicago sativa; Nicotiana; Plant Diseases; Plant Leaves; Plant Roots; Plants, Genetically Modified; Plants, Toxic; Promoter Regions, Genetic; Recombinant Fusion Proteins; Resveratrol; Rosales; Stilbenes; Ultraviolet Rays | 2001 |
Large-scale separation of resveratrol, anthraglycoside A and anthraglycoside B from Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.
Topics: Anthracenes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Glycosides; Polygonum; Resveratrol; Spectrum Analysis; Stilbenes | 2001 |
Effects of 1alpha,25-(OH)(2)D(3) on rat growth zone chondrocytes are mediated via cyclooxygenase-1 and phospholipase A(2).
Topics: Alkaline Phosphatase; Animals; Arachidonic Acid; Blotting, Northern; Calcitriol; Cells, Cultured; Chondrocytes; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Growth Plate; Indomethacin; Isoenzymes; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Membrane Proteins; Nitrobenzenes; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Proteoglycans; Rats; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Sulfonamides; Thymidine; Umbelliferones | 2001 |
Resveratrol inhibits the proliferation of normal human keratinocytes in vitro.
Topics: Antineoplastic Agents; Calcium; Cell Count; Cell Division; Cells, Cultured; Humans; Indicators and Reagents; Ionomycin; Ionophores; Keratinocytes; Resveratrol; Stilbenes; Tetrazolium Salts; Thymidine | 2001 |
Resveratrol inhibits the expression of cyclooxygenase-2 in mammary epithelial cells.
Topics: Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epithelial Cells; Female; Humans; Isoenzymes; Mammary Glands, Animal; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes | 2001 |
Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes.
Topics: Allantois; Angiogenesis Inhibitors; Animals; Cell Division; Chick Embryo; Chorion; Cornea; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Fibroblast Growth Factor 2; Fibrosarcoma; Lymphokines; Mice; Mitogen-Activated Protein Kinases; Neoplasms; Neovascularization, Pathologic; Neovascularization, Physiologic; Resveratrol; Rosales; Stilbenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wine; Wound Healing | 2001 |
Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines.
Topics: Alkaline Phosphatase; Anticarcinogenic Agents; Apoptosis; Caco-2 Cells; Caspase 3; Caspases; Cell Cycle; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; G2 Phase; Humans; Immunoblotting; Proto-Oncogene Proteins; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured | 2001 |
Resveratrol and quercetin inhibit angiogenesis in vitro.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cattle; Cell Division; Cell Movement; Cells, Cultured; Endothelium, Vascular; Neovascularization, Physiologic; Quercetin; Resveratrol; Stilbenes | 2001 |
Four new stilbene dimers from the lianas of Gnetum hainanense.
Topics: China; Chromatography, High Pressure Liquid; Cycadopsida; Dimerization; Mass Spectrometry; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism; Stilbenes | 2001 |
Antioxidant activity of resveratrol in endotoxin-stimulated blood platelets.
Topics: Animals; Antioxidants; Blood Platelets; Endotoxins; Hemostatics; Lipopolysaccharides; Luminescent Measurements; Reactive Oxygen Species; Regression Analysis; Resveratrol; Stilbenes; Superoxides; Swine; Thiobarbituric Acid Reactive Substances; Thrombin | 2001 |
Resveratrol exhibits cytostatic and antiestrogenic properties with human endometrial adenocarcinoma (Ishikawa) cells.
Topics: Adenocarcinoma; Alkaline Phosphatase; Antigens, CD; Antineoplastic Agents, Phytogenic; CDC2-CDC28 Kinases; Cell Survival; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Down-Regulation; Drug Interactions; Endometrial Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha1; Protein Serine-Threonine Kinases; Receptors, Estrogen; Receptors, Progesterone; Resveratrol; RNA, Messenger; S Phase; Stilbenes; Transcriptional Activation; Tumor Cells, Cultured | 2001 |
Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia.
Topics: Animals; Blood Gas Analysis; Brain Ischemia; Dose-Response Relationship, Drug; Hemodynamics; Hydrogen-Ion Concentration; Infarction, Middle Cerebral Artery; Ligation; Male; Rats; Rats, Long-Evans; Resveratrol; Stilbenes; Vasodilator Agents | 2001 |
On-line identification of trans- and cis-resveratrol by nonaqueous capillary electrophoresis/fluorescence spectroscopy at 77 K.
Topics: Acetates; Acetonitriles; Cold Temperature; Electrophoresis, Capillary; Isomerism; Methanol; Photochemistry; Resveratrol; Sodium Cholate; Solubility; Solvents; Spectrometry, Fluorescence; Stilbenes | 2001 |
Do wine polyphenols modulate p53 gene expression in human cancer cell lines?
Topics: Antioxidants; Breast Neoplasms; Caffeic Acids; Catechin; Colonic Neoplasms; Flavonoids; Fluoroimmunoassay; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Models, Structural; Phenols; Polymers; Quercetin; Resveratrol; Stilbenes; Time Factors; Tumor Cells, Cultured; Wine | 2001 |
Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Breast; Cell Cycle; Cell Division; Cell Line, Transformed; Comet Assay; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Fibroblasts; Flow Cytometry; Humans; Mice; Nucleosomes; Oxidation-Reduction; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Protective effects of resveratrol on hydrogen peroxide-induced apoptosis in rat pheochromocytoma (PC12) cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Survival; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Hydrogen Peroxide; In Situ Nick-End Labeling; NF-kappa B; Nucleosomes; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2001 |
Anti-inflammatory tetramers of resveratrol from the roots of Vitis amurensis and the conformations of the seven-membered ring in some oligostilbenes.
Topics: Anti-Inflammatory Agents; Biopolymers; Molecular Conformation; Plant Roots; Resveratrol; Spectrum Analysis; Stilbenes; Vitis | 2001 |
Regioselective and stereospecific glucuronidation of trans- and cis-resveratrol in human.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Glucuronic Acid; Glucuronosyltransferase; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes, Liver; Molecular Conformation; Recombinant Proteins; Resveratrol; Stilbenes; UDP-Glucuronosyltransferase 1A9 | 2001 |
Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves.
Topics: Adenosine; Animals; Blotting, Western; Calcitonin Gene-Related Peptide; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Denervation; Digestive System; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Gene Expression Regulation, Enzymologic; Indomethacin; Ischemic Preconditioning; Isoenzymes; Lactones; Male; Membrane Proteins; Neurons, Afferent; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfones; Theophylline; Time Factors | 2001 |
Bcl-2 overexpression attenuates resveratrol-induced apoptosis in U937 cells by inhibition of caspase-3 activity.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Chromosomal Proteins, Non-Histone; Cyclin-Dependent Kinases; Cyclins; Cytochrome c Group; Flow Cytometry; Humans; Inhibitor of Apoptosis Proteins; Isoenzymes; Microtubule-Associated Proteins; Neoplasm Proteins; Phospholipase C gamma; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Survivin; Transfection; Type C Phospholipases; U937 Cells; Viral Proteins | 2001 |
Resveratrol inhibits intestinal tumorigenesis and modulates host-defense-related gene expression in an animal model of human familial adenomatous polyposis.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Cell Division; Disease Models, Animal; Gene Expression Regulation; Immunity, Cellular; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Treatment Outcome | 2001 |
Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cytochrome P-450 CYP1A1; Enzyme Stability; Gene Silencing; Humans; Receptors, Aryl Hydrocarbon; Resveratrol; RNA Processing, Post-Transcriptional; RNA Stability; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2001 |
[Chemical research on stilbenes from Veratrum macckii Reg].
Topics: Drugs, Chinese Herbal; Molecular Structure; Resveratrol; Stilbenes; Veratrum | 1998 |
Postharvest induction modeling method using UV irradiation pulses for obtaining resveratrol-enriched table grapes: a new "functional" fruit?
Topics: Anthocyanins; Ascorbic Acid; Chromatography, High Pressure Liquid; Diet; Food Technology; Health Promotion; Kinetics; Models, Theoretical; Phenols; Resveratrol; Sensation; Stilbenes; Ultraviolet Rays; Vitis | 2001 |
Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Ductal, Breast; Estrogens; Female; Humans; Luciferases; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Progesterone; Response Elements; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Sepsis-induced alteration in T-cell Ca(2+) signaling in neonatal rats.
Topics: Animals; Animals, Newborn; Bacteroides Infections; Calcium; Concanavalin A; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Escherichia coli Infections; Isoenzymes; Lymphocyte Activation; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Resveratrol; Sepsis; Signal Transduction; Spleen; Stilbenes; Sulfonamides; T-Lymphocytes | 2001 |
Involvement of the retinoblastoma (pRb)-E2F/DP pathway during antiproliferative effects of resveratrol in human epidermoid carcinoma (A431) cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; G1 Phase; Humans; Resveratrol; Retinoblastoma Protein; Stilbenes; Transcription Factors; Tumor Cells, Cultured | 2001 |
Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts.
Topics: Adolescent; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Caspase 3; Caspases; Cell Nucleus; Child; Child, Preschool; DNA Fragmentation; Dose-Response Relationship, Drug; fas Receptor; Female; Humans; Infant; Leukemia, Lymphoid; Male; Membrane Potentials; Mitochondria; Resveratrol; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2001 |
Resveratrol analog, 3,5,2',4'-tetramethoxy-trans-stilbene, potentiates the inhibition of cell growth and induces apoptosis in human cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Nucleus; Flow Cytometry; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2001 |
Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Microsomes, Liver; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Resveratrol; Stilbenes; Wine | 2001 |
Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production.
Topics: Adjuvants, Immunologic; Animals; Cell Division; Cells, Cultured; Cytokines; Immunity, Cellular; Interleukin-2; Lymphocytes; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; NF-kappa B; Resveratrol; RNA, Messenger; Stilbenes | 2001 |
Resveratrol-induced inactivation of human gastric adenocarcinoma cells through a protein kinase C-mediated mechanism.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Division; DNA, Neoplasm; Humans; Mitogen-Activated Protein Kinases; Protein Kinase C; Resveratrol; Stilbenes; Stomach Neoplasms; Tumor Cells, Cultured | 2001 |
Protective effect of resveratrol against intracortical FeCl3-induced model of posttraumatic seizures in rats.
Topics: Animals; Antioxidants; Brain; Chlorides; Electroencephalography; Epilepsy, Post-Traumatic; Female; Ferric Compounds; Free Radicals; Glutathione; Injections, Intraventricular; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Resveratrol; Seizures; Stilbenes | 2001 |
Stilbene compounds and stilbene synthase expression during ripening, wilting, and UV treatment in grape cv. Corvina.
Topics: Acyltransferases; Blotting, Northern; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic; Ultraviolet Rays; Vitis | 2001 |
Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2.
Topics: Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; NADP; Oxazines; Recombinant Proteins; Resveratrol; Stilbenes; Substrate Specificity | 2001 |
Different effects of genistein and resveratrol on oxidative DNA damage in vitro.
Topics: Anticarcinogenic Agents; Antioxidants; Copper; DNA; DNA Damage; Genistein; Hydrogen Peroxide; Hydroquinones; Oxidation-Reduction; Resveratrol; Stilbenes | 2002 |
Effect of estradiol, diethylstilbestrol, and resveratrol on F0F1-ATPase activity from mitochondrial preparations of rat heart, liver, and brain.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Binding, Competitive; Brain; Diethylstilbestrol; Digitonin; Enzyme Activation; Enzyme Inhibitors; Estradiol; Hydrolysis; Iodine Radioisotopes; L-Lactate Dehydrogenase; Male; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Proton-Translocating ATPases; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Resveratrol; Serum Albumin, Bovine; Solubility; Stilbenes | 2001 |
Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines.
Topics: 3T3 Cells; Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cell Survival; Electron Transport Complex IV; Enzyme Inhibitors; Female; Humans; Kinetics; Mice; Protein Denaturation; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 2002 |
Resveratrol induces colon tumor cell apoptosis independently of p53 and precede by epithelial differentiation, mitochondrial proliferation and membrane potential collapse.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Differentiation; Cell Division; Colonic Neoplasms; Epithelial Cells; Humans; Membrane Potentials; Mitochondria; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Inhibition of protein kinase D by resveratrol.
Topics: Animals; COS Cells; Enzyme Inhibitors; Phosphorylation; Protein Kinase C; Resveratrol; Serine; Stilbenes | 2001 |
Effects of resveratrol on human immune cell function.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunity, Cellular; Killer Cells, Natural; Lymphocyte Activation; Monocytes; Resveratrol; Stilbenes; T-Lymphocytes, Cytotoxic | 2001 |
Effects of resveratrol on oxidative modification of human low density lipoprotein.
Topics: Animals; Antioxidants; Azo Compounds; Cells, Cultured; Copper; Dose-Response Relationship, Drug; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Malondialdehyde; Mice; Oxidation-Reduction; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Time Factors | 2000 |
Analysis of trans-resveratrol by laser desorption coupled with resonant ionization spectrometry. Application to trans-resveratrol content in vine leaves and grape skin.
Topics: Lasers; Mass Spectrometry; Plant Leaves; Reproducibility of Results; Resveratrol; Stilbenes; Vitis | 2001 |
An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine.
Topics: Antioxidants; Beverages; Chromatography, Liquid; Fruit; Light; Mass Spectrometry; Reproducibility of Results; Resveratrol; Stilbenes; Vitis; Wine | 2002 |
The possible implication of trans-Resveratrol in the cardioprotective effects of long-term moderate wine consumption.
Topics: Animals; Aorta; Cardiotonic Agents; In Vitro Techniques; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Resveratrol; Stereoisomerism; Stilbenes; Superoxides; Vasodilation; Xanthine Oxidase | 2002 |
Effect of resveratrol on the expression of autocrine growth modulators in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Estradiol; Humans; Insulin-Like Growth Factor I; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Transforming Growth Factor beta3; Tumor Cells, Cultured | 2001 |
The daily oral administration of high doses of trans-resveratrol to rats for 28 days is not harmful.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Arachis; Body Weight; Drinking; Eating; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors; Viscera; Vitis; Wine | 2002 |
Vaticanol C, a novel resveratrol tetramer, inhibits cell growth through induction of apoptosis in colon cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Colonic Neoplasms; DNA, Neoplasm; Humans; Molecular Weight; Plant Epidermis; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Anti-hepatoma activity of resveratrol in vitro.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Humans; In Vitro Techniques; Liver Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Ultra-low-temperature non-aqueous capillary electrophoretic separation--77 K fluorescence spectroscopic detection for the on-line identification of photo-converted analytes of trans-resveratrol.
Topics: Cold Temperature; Electrophoresis, Capillary; Photochemistry; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2002 |
Effects of resveratrol, a flavinoid found in red wine, on infarct size in an experimental model of ischemia/reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Pressure; Body Weight; Flavonoids; Heart Rate; Heart Ventricles; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Regional Blood Flow; Resveratrol; Risk Factors; Stilbenes; Wine | 2001 |
Simultaneous determination of trans-resveratrol and sorbic acid in wine by capillary zone electrophoresis.
Topics: Electrophoresis, Capillary; Resveratrol; Sorbic Acid; Stilbenes; Time Factors; Wine | 2002 |
Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Arthrodermataceae; Cell Division; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Resveratrol; Skin; Staphylococcus aureus; Stilbenes; Trichophyton | 2002 |
Resveratrol: phytoestrogen effects on reproductive physiology and behavior in female rats.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrogens, Non-Steroidal; Estrous Cycle; Female; Isoflavones; Organ Size; Ovariectomy; Ovary; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Reproduction; Resveratrol; Sexual Behavior, Animal; Stilbenes; Uterus; Vagina | 2002 |
Mechanism of resveratrol-mediated suppression of tissue factor gene expression.
Topics: Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Lipopolysaccharides; Monocytes; Neoplasm Proteins; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Resveratrol; RNA, Messenger; RNA, Neoplasm; Stilbenes; Thromboplastin; Transcription Factor AP-1; Transcription Factor RelA; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2002 |
Effect of resveratrol on growth of 4T1 breast cancer cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Dose-Response Relationship, Drug; Female; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYP1B1.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Chemoprevention; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured; Wine | 2002 |
Peanut roots as a source of resveratrol.
Topics: Antioxidants; Arachis; Chromatography, High Pressure Liquid; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Mass Spectrometry; Peanut Oil; Plant Oils; Plant Roots; Resveratrol; Seasons; Stilbenes | 2002 |
Resveratrol activates membrane-bound guanylyl cyclase in coronary arterial smooth muscle: a novel signaling mechanism in support of coronary protection.
Topics: Animals; Coronary Vessels; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; omega-N-Methylarginine; Platelet Aggregation Inhibitors; Protective Agents; Resveratrol; Sheep; Signal Transduction; Stilbenes | 2002 |
Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism.
Topics: Adenocarcinoma, Follicular; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Papillary; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Resveratrol; RNA, Messenger; Stilbenes; Thyroid Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
The action of dietary phytochemicals quercetin, catechin, resveratrol and naringenin on estrogen-mediated gene expression.
Topics: Animals; Apolipoproteins; Catechin; Chickens; Cytosol; Dose-Response Relationship, Drug; Drug Combinations; Estradiol; Estrogen Antagonists; Estrogens, Non-Steroidal; Flavanones; Flavonoids; Gene Expression; Liver; Male; Plant Preparations; Protein Precursors; Quercetin; Resveratrol; RNA-Binding Proteins; RNA, Messenger; Stilbenes | 2002 |
Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.
Topics: Apoptosis; Blotting, Western; Cell Division; Cytokines; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation; Growth Differentiation Factor 15; Humans; Resveratrol; RNA, Messenger; Stilbenes; Structure-Activity Relationship; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.
Topics: Anticarcinogenic Agents; Apoptosis; Biomarkers, Tumor; Cell Cycle; Cell Division; Cyclin D1; Cyclins; DNA Primers; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunoblotting; Luciferases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotide Reductases; RNA, Messenger; RNA, Neoplasm; S Phase; Stilbenes; Tumor Cells, Cultured | 2002 |
Resveratrol acts as a natural profungicide and induces self-intoxication by a specific laccase.
Topics: Amino Acid Sequence; Antifungal Agents; Arachis; Base Sequence; Botrytis; DNA, Fungal; Gene Expression; Genes, Fungal; Hydrolyzable Tannins; Laccase; Molecular Sequence Data; Mutagenesis; Oxidoreductases; Phenols; Plant Leaves; Prodrugs; Resveratrol; Sequence Homology, Amino Acid; Stilbenes; Virulence; Vitis | 2002 |
Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line; DNA Fragmentation; Epidermis; Gene Expression Regulation; Genes, p53; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Recombinant Proteins; Resveratrol; Stilbenes; Transcription, Genetic; Transfection | 2002 |
The protective effect of resveratrols on ischaemia-reperfusion injuries of rat hearts is correlated with antioxidant efficacy.
Topics: Animals; Biphenyl Compounds; Disease Models, Animal; Free Radical Scavengers; Humans; Lipoproteins, LDL; Male; Myocardial Ischemia; Oxidation-Reduction; Picrates; Protective Agents; Rats; Rats, Inbred WKY; Reperfusion Injury; Resveratrol; Stilbenes; Superoxides | 2002 |
Effect of resveratrol on platelet aggregation in vivo and in vitro.
Topics: Animals; Arteriosclerosis; Cholesterol, LDL; Humans; Lipids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Resveratrol; Stilbenes | 2002 |
Differential regulation of neutrophil phospholipase d activity and degranulation.
Topics: Catechin; Cell Degranulation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phosphatidic Acids; Phospholipase D; Resveratrol; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate | 2002 |
Benefits of resveratrol in women's health.
Topics: Animals; Anthocyanins; Anticarcinogenic Agents; Antioxidants; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Female; Free Radicals; Heart Diseases; Humans; Isoflavones; Phytoestrogens; Plant Preparations; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Ventricular Fibrillation | 2001 |
Inhibition of gastric cancer cell proliferation by resveratrol: role of nitric oxide.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; DNA; Humans; Hydrogen Peroxide; Ionomycin; Ionophores; NADP; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oxidants; Protein Kinase C; Reactive Oxygen Species; Resveratrol; Stilbenes; Stomach Neoplasms; Superoxides; Tumor Cells, Cultured | 2002 |
Potential cancer-chemopreventive activities of wine stilbenoids and flavans extracted from grape (Vitis vinifera) cell cultures.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Biflavonoids; Catechin; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Isoenzymes; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Oxygen Consumption; Phenols; Plant Extracts; Proanthocyanidins; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Vitis; Wine | 2001 |
[In vitro protection of cerebral mitochondrial function by E-resveratrol in anoxia followed by re-oxygenation].
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Cerebral Cortex; Cytochrome c Group; Dose-Response Relationship, Drug; Hypoxia, Brain; Mitochondria; Rats; Resveratrol; Stilbenes | 2001 |
Resveratrol induces prostate cancer cell entry into s phase and inhibits DNA synthesis.
Topics: Androgens; Animals; Antineoplastic Agents, Phytogenic; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Division; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Humans; Male; Mice; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Resveratrol; S Phase; Stilbenes; Tumor Suppressor Proteins | 2002 |
Stable isotope labeling pattern of resveratrol and related natural stilbenes.
Topics: Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Resveratrol; Stilbenes | 2002 |
A comparison of the anticarcinogenic properties of four red wine polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Catechin; Flavonoids; Gallic Acid; Mice; Phenols; Polymers; Quercetin; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Wine | 2002 |
Comparison of the antinociceptive effect of celecoxib, diclofenac and resveratrol in the formalin test.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Female; Formaldehyde; Inflammation; Pain; Pyrazoles; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfonamides | 2002 |
Interactive gene expression pattern in prostate cancer cells exposed to phenolic antioxidants.
Topics: Anticarcinogenic Agents; Antioxidants; Carcinoma; DNA, Neoplasm; Ellagic Acid; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Oligonucleotide Array Sequence Analysis; Phenols; Prostatic Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2002 |
Pharmacological preconditioning with resveratrol: role of nitric oxide.
Topics: Animals; Apoptosis; Enzyme Inhibitors; Gene Expression; Guanidines; Heart Ventricles; Ischemic Preconditioning; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2002 |
Pharmacological preconditioning with resveratrol: an insight with iNOS knockout mice.
Topics: Animals; Apoptosis; Enzyme Inhibitors; Gene Expression; Guanidines; Heart; Ischemic Preconditioning; Kinetics; Male; Malondialdehyde; Mice; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Resveratrol; RNA, Messenger; Stilbenes | 2002 |
Determination of antioxidant power of red and white wines by a new electrochemical method and its correlation with polyphenolic content.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Electrochemistry; Flavonoids; Phenols; Polymers; Polyphenols; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Wine | 2002 |
Plant foods and herbal sources of resveratrol.
Topics: Animals; Arachis; Biological Availability; Glycine max; Intestinal Absorption; Plants, Edible; Resveratrol; Stilbenes; Tea; Vitis; Wine | 2002 |
[Effects of isorhapotigenin and resveratrol on function of peripheral blood polymorphonuclear leukocytes from rabbits].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis, Leukocyte; Glucuronidase; Neutrophils; Rabbits; Resveratrol; Stilbenes | 1998 |
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.
Topics: Anticarcinogenic Agents; Antioxidants; Cucumis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Organ Culture Techniques; Peroxides; Phenols; Prostaglandin-Endoperoxide Synthases; Resveratrol; Singlet Oxygen; Stilbenes | 2002 |
Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Biopolymers; Cell Division; Drug Screening Assays, Antitumor; Fungi; Humans; Microbial Sensitivity Tests; Organophosphates; Prodrugs; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured | 2002 |
Protective effect of resveratrol against pentylenetetrazole-induced seizures and its modulation by an adenosinergic system.
Topics: Adenosine; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Pentylenetetrazole; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Resveratrol; Seizures; Stilbenes; Theophylline | 2002 |
Inhibition of vascular smooth muscle cell proliferation with red wine and red wine polyphenols.
Topics: Animals; Antioxidants; Cattle; Cell Division; Cells, Cultured; Flavonoids; L-Lactate Dehydrogenase; Muscle, Smooth, Vascular; Phenols; Polymers; Polyphenols; Resveratrol; Stilbenes; Trypan Blue; Wine | 2002 |
Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay.
Topics: Acetylcysteine; Antioxidants; Ascorbic Acid; Breast Neoplasms; Cell Division; Cell Survival; Drug Interactions; Estrogens, Non-Steroidal; Flavonoids; Humans; Isoflavones; Kaempferols; Phytoestrogens; Plant Extracts; Plant Preparations; Plants; Quercetin; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vitamin E | 2002 |
Principal component analysis of biogenic amines and polyphenols in Hungarian wines.
Topics: Biogenic Amines; Chromatography; Flavonoids; Hungary; Phenols; Polymers; Polyphenols; Resveratrol; Spectrophotometry; Stilbenes; Wine | 2002 |
Analysis of resveratrol-induced apoptosis in human B-cell chronic leukaemia.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Cell Division; Gene Expression; Genes, bcl-2; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Bile; Biotransformation; Enterohepatic Circulation; Glucuronides; Intestinal Absorption; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tissue Distribution | 2002 |
A culture of mistrust.
Topics: Antineoplastic Agents; Calcium; Carotenoids; Communication Barriers; Diet; Humans; Lycopene; Mass Media; Medical Oncology; Neoplasms; Resveratrol; Solanum lycopersicum; Stilbenes; Wine | 2002 |
Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats.
Topics: Animals; Brain; Disease Models, Animal; Drug Administration Schedule; Free Radicals; Hand Strength; Ischemic Attack, Transient; Male; Malondialdehyde; Middle Cerebral Artery; Motor Activity; Muscle, Skeletal; Oxidative Stress; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reference Values; Reperfusion Injury; Resveratrol; Stilbenes; Stroke; Time Factors | 2002 |
Resveratrol, a component of wine and grapes, in the prevention of kidney disease.
Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Ischemia; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury; Resveratrol; Stilbenes; Vitis; Wine | 2002 |
Resveratrol, a natural product derived from grapes, is a new inducer of differentiation in human myeloid leukemias.
Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion Molecules; Cell Differentiation; Cell Division; Drug Synergism; Humans; Leukemia, Myeloid; NF-kappa B; Resveratrol; Stilbenes; Superoxides; Tretinoin; Tumor Cells, Cultured; Vitis | 2002 |
Resveratrol modulates rat macrophage functions.
Topics: Adjuvants, Immunologic; Animals; Dose-Response Relationship, Drug; Kluyveromyces; Macrophages; Male; Nitrites; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2002 |
Anti-aromatase chemicals in red wine.
Topics: Aromatase Inhibitors; Enzyme Inhibitors; Quercetin; Resveratrol; Rutin; Stilbenes; Wine | 2002 |
Disparate in vitro and in vivo antileukemic effects of resveratrol, a natural polyphenolic compound found in grapes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Flavonoids; In Vitro Techniques; Leukemia; Male; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Phenols; Polymers; Polyphenols; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vitis | 2002 |
Resveratrol enhances the differentiation induced by butyrate in caco-2 colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Butyrates; Caco-2 Cells; Cell Differentiation; Colonic Neoplasms; Drug Synergism; Humans; Resveratrol; Stilbenes | 2002 |
Comparative evaluation of the effect of antioxidants in the conservation of ram semen.
Topics: alpha-Tocopherol; Animals; Antioxidants; Glutathione Peroxidase; Hydrocarbons; Lipid Peroxidation; Male; Resveratrol; Semen Preservation; Sheep; Spermatozoa; Stilbenes; Tocopherols; Vitamin E | 2002 |
On-line EPR study of free radicals induced by peroxidase/H(2)O(2) in human low-density lipoprotein.
Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Nitroso Compounds; Oxidants; Resveratrol; Spin Trapping; Stilbenes; Temperature | 2002 |
Resveratrol, a chemopreventive agent, disrupts the cell cycle control of human SW480 colorectal tumor cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Colorectal Neoplasms; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA Replication; Enzyme Induction; Flow Cytometry; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured | 2002 |
Aryl hydrocarbon receptor is required for prevention of blood clotting and for the development of vasculature and bone in the embryos of medaka fish, Oryzias latipes.
Topics: Acetylcysteine; Animals; Base Sequence; Benzoflavones; Blood Coagulation; Blood Vessels; Bone and Bones; Conserved Sequence; DNA, Complementary; Evolution, Molecular; Gene Expression Regulation; Oryzias; Phenotype; Piperonyl Butoxide; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Sequence Homology, Nucleic Acid; Stilbenes | 2002 |
Inhibition of cancer growth by resveratrol is related to its low bioavailability.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Cell Adhesion; Cell Division; Half-Life; In Vitro Techniques; Integrin alpha4beta1; Liver; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Rabbits; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tissue Distribution; Vascular Cell Adhesion Molecule-1 | 2002 |
Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; DNA Mutational Analysis; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Prostatic Neoplasms; Proto-Oncogene Proteins p21(ras); Resveratrol; RNA, Messenger; Serine; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Resveratrol inhibits the growth and induces the apoptosis of both normal and leukemic hematopoietic cells.
Topics: Apoptosis; Bone Marrow Cells; Cell Division; Humans; Leukemia; Resveratrol; Stilbenes | 2002 |
Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Artemia; Benzodioxoles; Biphenyl Compounds; Cocarcinogenesis; Female; Free Radical Scavengers; Herpesvirus 4, Human; Lethal Dose 50; Mice; Mice, Inbred ICR; Phenols; Picrates; Plant Oils; Resveratrol; Sesame Oil; Skin Neoplasms; Stilbenes; Sunflower Oil; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2002 |
Efficiency and structure-activity relationship of the antioxidant action of resveratrol and its analogs.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain Chemistry; Erythrocytes; Hemolysis; Hydrogen Peroxide; Indicators and Reagents; Kidney; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Resveratrol; Stilbenes; Structure-Activity Relationship | 2002 |
Resveratrol modulates human mammary epithelial cell O-acetyltransferase, sulfotransferase, and kinase activation of the heterocyclic amine carcinogen N-hydroxy-PhIP.
Topics: Acetyltransferases; Anticarcinogenic Agents; Biotransformation; Breast; Carcinogens; DNA Adducts; Epithelial Cells; Female; Humans; Imidazoles; Phosphotransferases; Pyridines; Resveratrol; Stilbenes; Sulfotransferases | 2002 |
Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action.
Topics: Cells, Cultured; Diethylstilbestrol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Combinations; Electrophoresis; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Fulvestrant; Lipopolysaccharides; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Plant Extracts; Resveratrol; Stilbenes; Structure-Activity Relationship | 2002 |
The interaction of resveratrol with ferrylmyoglobin and peroxynitrite; protection against LDL oxidation.
Topics: Antioxidants; Drug Interactions; Humans; In Vitro Techniques; Lipoproteins, LDL; Metmyoglobin; Oxidation-Reduction; Peroxynitrous Acid; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2002 |
Anti-platelet effects of different phenolic compounds from Yucca schidigera Roezl. bark.
Topics: Adenosine Diphosphate; Animals; Drug Evaluation, Preclinical; Phenols; Plant Bark; Plant Preparations; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Structure-Activity Relationship; Swine; Thiobarbituric Acid Reactive Substances; Thrombin; Yucca | 2002 |
Resveratrol and vitamin C as antioxidants in blood platelets.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Lipid Peroxidation; Luminescent Measurements; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxides; Swine; Thiobarbituric Acid Reactive Substances | 2002 |
Suppression of N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumorigenesis in F344 rats by resveratrol.
Topics: Animals; Carcinogenicity Tests; Cyclooxygenase 1; Cyclooxygenase 2; Dimethylnitrosamine; Dinoprostone; Disease Models, Animal; Esophageal Neoplasms; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic | 2002 |
Inhibition of protein kinase CKII activity by resveratrol, a natural compound in red wine and grapes.
Topics: Adenosine Triphosphate; Anticarcinogenic Agents; Casein Kinase II; Catalysis; Enzyme Inhibitors; HeLa Cells; Humans; Indicators and Reagents; Kinetics; Phosphorylation; Protein Serine-Threonine Kinases; Resveratrol; Stilbenes; Vitis; Wine | 2002 |
Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Carcinogens; Cell Division; Cyclooxygenase 2; Female; Humans; Immunohistochemistry; Isoenzymes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Resveratrol induces apoptosis in LNCaP cells and requires hydroxyl groups to decrease viability in LNCaP and DU 145 cells.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Survival; Diethylstilbestrol; Estrogens, Non-Steroidal; Humans; Hydroxyl Radical; Male; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Trans-resveratrol oral administration does not affect the enzymatic activities in rat small intestine.
Topics: Administration, Oral; Animals; Intestine, Small; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2002 |
Induction of neutral endopeptidase and angiotensin-converting enzyme activity of SK-N-SH cells in vitro by quercetin and resveratrol.
Topics: Angiotensin-Converting Enzyme Inhibitors; Brain Neoplasms; Cell Count; Cell Division; Cell Line; Enzyme Induction; Enzyme Inhibitors; Humans; Kinetics; Neprilysin; Neuroblastoma; Peptidyl-Dipeptidase A; Protease Inhibitors; Quercetin; Resveratrol; Stilbenes; Tumor Cells, Cultured; Wine | 2002 |
A role for cyclooxygenase-2 in lipopolysaccharide-induced anorexia in rats.
Topics: Analgesics, Non-Narcotic; Animals; Anorexia; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eating; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfonamides | 2002 |
Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Drug Interactions; Enzyme Activation; Hypertrophy; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases; Stilbenes | 2002 |
Neuroprotective effect of estradiol and phytoestrogens on MPP+-induced cytotoxicity in neuronal PC12 cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Blotting, Western; Carrier Proteins; Cell Death; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Estradiol; Estrogens, Non-Steroidal; Isoflavones; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neuroprotective Agents; PC12 Cells; Phytoestrogens; Plant Preparations; Quercetin; Rats; Receptors, Estrogen; Resveratrol; Stilbenes | 2002 |
Resveratrol affects in a different way primary versus fixed DNA damage induced by H(2)O(2) in mammalian cells in vitro.
Topics: Animals; Antioxidants; CHO Cells; Chromosome Aberrations; Comet Assay; Cricetinae; DNA Damage; Drug Interactions; Flow Cytometry; Fluoresceins; Free Radical Scavengers; Hydrogen Peroxide; Reactive Oxygen Species; Resveratrol; Stilbenes | 2002 |
Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats.
Topics: Animals; Antioxidants; Behavior, Animal; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Injections, Intraventricular; Learning; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2002 |
Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase.
Topics: Cells, Cultured; Electrophoretic Mobility Shift Assay; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Enzyme Induction; Estrogen Antagonists; Estrogens, Non-Steroidal; Flavonoids; Humans; Isoflavones; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nuclease Protection Assays; Phenols; Phytoalexins; Phytoestrogens; Plant Extracts; Plant Preparations; Polymers; Polyphenols; Promoter Regions, Genetic; Receptors, Estrogen; Resveratrol; RNA Stability; RNA, Messenger; Sesquiterpenes; Stilbenes; Terpenes; Up-Regulation; Wine | 2002 |
Resveratrol suppresses agonist-induced monocyte adhesion to cultured human endothelial cells.
Topics: Cell Adhesion; Cytokines; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; E-Selectin; Endothelium, Vascular; Humans; Monocytes; Resveratrol; RNA, Messenger; Stilbenes; Tumor Cells, Cultured; Umbilical Veins | 2002 |
Antioxidant effects of resveratrol and its analogues against the free-radical-induced peroxidation of linoleic acid in micelles.
Topics: alpha-Tocopherol; Antioxidants; Cetrimonium; Cetrimonium Compounds; Electrochemistry; Free Radicals; Kinetics; Linoleic Acid; Lipid Peroxidation; Micelles; Molecular Structure; Resveratrol; Sodium Dodecyl Sulfate; Stilbenes; Wine | 2002 |
Low dose of resveratrol enhanced immune response of mice.
Topics: Adjuvants, Immunologic; Animals; Dinitrofluorobenzene; Hypersensitivity, Delayed; Immunity; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-2; Mice; Mice, Inbred BALB C; Resveratrol; Spleen; Stilbenes; T-Lymphocyte Subsets | 2002 |
Effects of resveratrol on the G(0)-G(1) transition and cell cycle progression of mitogenically stimulated human lymphocytes.
Topics: Acridine Orange; Angiogenesis Inhibitors; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cyclin D2; Cyclin D3; Cyclin E; Cyclins; DNA; Flow Cytometry; G1 Phase; Humans; Immunohistochemistry; Lymphocytes; Mitogens; Proliferating Cell Nuclear Antigen; Resting Phase, Cell Cycle; Resveratrol; Retinoblastoma Protein; RNA; Stilbenes; Time Factors | 2002 |
Dermal wound healing properties of redox-active grape seed proanthocyanidins.
Topics: Animals; Anthocyanins; Cell Line, Transformed; Drug Evaluation, Preclinical; Endothelial Growth Factors; Epithelial Cells; Feasibility Studies; Gene Expression Regulation; Genes, Reporter; Glutathione; Humans; Intercellular Signaling Peptides and Proteins; Keratinocytes; Luciferases; Lymphokines; Male; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; Oxidants; Oxidation-Reduction; Phytotherapy; Plant Extracts; Proanthocyanidins; Resveratrol; Seeds; Skin; Stilbenes; Tenascin; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitis; Wound Healing; Wounds, Stab | 2002 |
Postharvest stilbene-enrichment of red and white table grape varieties using UV-C irradiation pulses.
Topics: Chromatography, High Pressure Liquid; Food Irradiation; Food, Organic; Gas Chromatography-Mass Spectrometry; Kinetics; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2002 |
Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Survival; Colorectal Neoplasms; Humans; Membrane Potentials; Mitochondria; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
The peripheral antinociceptive effect of resveratrol is associated with activation of potassium channels.
Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; ATP-Binding Cassette Transporters; Charybdotoxin; Female; Glipizide; Glyburide; KATP Channels; Morphine; Narcotics; Peripheral Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Tolbutamide | 2002 |
The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Survival; Enzyme Inhibitors; Humans; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tumor Cells, Cultured | 2002 |
Antioxidative activity of resveratrol and its derivatives isolated from seeds of Paeonia lactiflora.
Topics: Animals; Antioxidants; Deoxyribose; Hepatocytes; Hydroxyl Radical; Lipid Peroxidation; Microsomes, Liver; Molecular Structure; Paeonia; Rats; Resveratrol; Seeds; Stilbenes | 2002 |
Resveratrol- induced apoptosis is mediated by p53-dependent pathway in Hep G2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; fas Receptor; Growth Inhibitors; Humans; Kinetics; Liver Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Resveratrol inhibits proliferation and induces apoptosis in human pancreatic cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Division; Coloring Agents; DNA; Dose-Response Relationship, Drug; Humans; In Situ Nick-End Labeling; Kinetics; Pancreatic Neoplasms; Propidium; Resveratrol; Stilbenes; Thymidine; Tumor Cells, Cultured | 2002 |
Effects of resveratrol and ethanol on production of pro-inflammatory factors from endotoxin activated murine macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Synergism; Endotoxins; Ethanol; Interleukin-1; Interleukin-6; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2002 |
Flavonoid effects relevant to cancer.
Topics: Breast Neoplasms; Cell Division; Cell Survival; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Non-Steroidal; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Humans; Isoflavones; Phosphorylation; Phytoestrogens; Plant Preparations; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Hormonal and genotoxic activity of resveratrol.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Fluorescein-5-isothiocyanate; Humans; Kinetochores; Lymphoma; Metaphase; Mice; Micronucleus Tests; Molecular Structure; Protein Binding; Receptors, Estrogen; Resveratrol; Stilbenes; Time Factors; Tubulin; Tumor Cells, Cultured | 2002 |
[Role of free radicals in blood platelet activation].
Topics: Antioxidants; Chromans; Free Radicals; Humans; Platelet Aggregation; Resveratrol; Stilbenes | 2002 |
Molecular analysis on the chemopreventive properties of resveratrol, a plant polyphenol microcomponent.
Topics: Antineoplastic Agents, Phytogenic; Cell Division; Colonic Neoplasms; Flow Cytometry; Genistein; Hepatoblastoma; Humans; In Vitro Techniques; Neoplasms; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured | 2002 |
Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin.
Topics: Animals; Collagen; Dose-Response Relationship, Drug; Fibrinogen; Flavonoids; Lipopolysaccharides; Phenols; Platelet Activation; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Polymers; Polyphenols; Proteus mirabilis; Resveratrol; Stilbenes; Swine; Thrombin | 2002 |
The 4'-hydroxy group is responsible for the in vitro cytogenetic activity of resveratrol.
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytogenetic Analysis; Dose-Response Relationship, Drug; Micronucleus Tests; Mutagenicity Tests; Resveratrol; Sister Chromatid Exchange; Stilbenes; Structure-Activity Relationship | 2002 |
Antimicrobial resveratrol tetramers from the stem bark of Vatica oblongifoliassp. oblongifolia.
Topics: Ericales; Malaysia; Methicillin Resistance; Molecular Conformation; Molecular Structure; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Plant Stems; Plants, Medicinal; Resveratrol; Staphylococcus aureus; Stilbenes | 2002 |
Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-beta-D-glucopyranosides.
Topics: Drug Stability; Electrophoresis, Capillary; Glucosides; Resveratrol; Stilbenes; Wine | 2002 |
Resveratrol protects against global cerebral ischemic injury in gerbils.
Topics: Animals; Brain Ischemia; Cell Death; Gerbillinae; Hippocampus; Male; Neuroglia; Neurons; Reperfusion Injury; Resveratrol; Stilbenes | 2002 |
Kinetic evaluation of the reactivity of flavonoids as radical scavengers.
Topics: Catechin; Flavonoids; Free Radical Scavengers; Free Radicals; Hesperidin; Kinetics; Molecular Structure; Polymers; Propyl Gallate; Quercetin; Resveratrol; Stilbenes; Structure-Activity Relationship | 2002 |
Comparative antiproliferative and apoptotic effects of resveratrol, epsilon-viniferin and vine-shots derived polyphenols (vineatrols) on chronic B lymphocytic leukemia cells and normal human lymphocytes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Benzofurans; Caspase 3; Caspases; Cell Division; Flavonoids; Humans; Intracellular Membranes; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Membrane Potentials; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenols; Plant Extracts; Polymers; Polyphenols; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Vitis | 2002 |
Antioxidants induce different phenotypes by a distinct modulation of signal transduction.
Topics: Antioxidants; Apoptosis; DNA-Binding Proteins; DNA, Complementary; Early Growth Response Protein 1; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Models, Chemical; Phenotype; Phenylethyl Alcohol; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Pyrrolidines; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Thiocarbamates; Time Factors; Transcription Factors; Up-Regulation | 2002 |
Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antioxidants; Cells, Cultured; Colforsin; DNA-Binding Proteins; Drugs, Chinese Herbal; Gene Expression; Humans; Luciferases; Melanocytes; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Promoter Regions, Genetic; Resveratrol; Skin Pigmentation; Stilbenes; Swine; Thioctic Acid; Transcription Factors; Ultraviolet Rays | 2002 |
Improving postharvest resistance in fruits by external application of trans-resveratrol.
Topics: Agriculture; Botrytis; Food Preservation; Fruit; Malus; Plant Diseases; Resveratrol; Stilbenes; Vitis | 2003 |
Effect of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Caspase 7; Caspases; Cell Death; Cell Line; DNA; Humans; Immunoblotting; Mitogen-Activated Protein Kinases; Neuroblastoma; Paclitaxel; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Resveratrol; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2003 |
Human, rat, and mouse metabolism of resveratrol.
Topics: Animals; Female; Hepatocytes; Humans; Mice; Mice, Inbred BALB C; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Resveratrol; Species Specificity; Stilbenes | 2002 |
Inhibition of free radical-induced peroxidation of rat liver microsomes by resveratrol and its analogues.
Topics: Amidines; Animals; Antioxidants; Ascorbic Acid; Drug Design; Free Radicals; Kinetics; Lipid Peroxidation; Microsomes, Liver; Molecular Structure; Oxygen Consumption; Rats; Resveratrol; Stilbenes; Structure-Activity Relationship; Thiobarbituric Acid Reactive Substances | 2003 |
Inhibition of protein kinase C by resveratrol.
Topics: Calcium; Cardiotonic Agents; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Isoenzymes; Phosphatidylserines; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2003 |
[Studies on chemical constituents of Maackia amurensis Rupr. et. Maxim].
Topics: Isoflavones; Maackia; Plants, Medicinal; Resveratrol; Stilbenes; Trees | 2001 |
trans-Resveratrol and grape disease resistance. A dynamical study by high-resolution laser-based techniques.
Topics: Botrytis; Ethylenes; Fruit; Immunity, Innate; Oils, Volatile; Plant Diseases; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Vitis | 2003 |
Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspases; Cell Survival; Curcumin; Humans; Male; Membrane Glycoproteins; Prostatic Neoplasms; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
Effect of natural phenols on the catalytic activity of cytochrome P450 2E1.
Topics: Animals; Binding, Competitive; Catalysis; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Female; Hydrolyzable Tannins; Hydroxylation; Inhibitory Concentration 50; Kinetics; Mice; Microsomes, Liver; Molecular Structure; Phenols; Resveratrol; Stilbenes; Substrate Specificity | 2002 |
[Estrogenicity of trans-resveratrol in immature mice in vivo].
Topics: Animals; Endometrium; Epithelial Cells; Estrogens, Non-Steroidal; Female; Isoflavones; Mice; Phytoestrogens; Plant Preparations; Resveratrol; Stilbenes; Vagina | 2002 |
[Determination of resveratrol in grape wine by high performance liquid chromatography].
Topics: Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Resveratrol; Stilbenes; Vitis; Wine | 1999 |
Absorption of three wine-related polyphenols in three different matrices by healthy subjects.
Topics: Administration, Oral; Adult; Antioxidants; Catechin; Chromatography, Gas; Flavonoids; Glucose; Humans; Male; Middle Aged; Models, Chemical; Phenols; Polymers; Quercetin; Resveratrol; Stilbenes; Time Factors; Wine | 2003 |
Resveratrol is a potent inducer of apoptosis in human melanoma cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Division; DNA Fragmentation; Humans; MAP Kinase Signaling System; Melanoma; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2003 |
Sequestering ability of butylated hydroxytoluene, propyl gallate, resveratrol, and vitamins C and E against ABTS, DPPH, and hydroxyl free radicals in chemical and biological systems.
Topics: Antioxidants; Apomorphine; Ascorbic Acid; Benzothiazoles; beta Carotene; Biphenyl Compounds; Butylated Hydroxytoluene; Hydrogen Peroxide; Hydroxyl Radical; Oxidation-Reduction; Paraquat; Picrates; Propyl Gallate; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Sulfonic Acids; Vitamin E | 2003 |
Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.
Topics: Animals; Baculoviridae; Chromatography, Liquid; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Insecta; Isoenzymes; Mass Spectrometry; Molecular Structure; Recombinant Proteins; Resveratrol; Stilbenes | 2003 |
Differential expression of genes induced by resveratrol in LNCaP cells: P53-mediated molecular targets.
Topics: Acetyltransferases; Apoptosis; Apoptotic Protease-Activating Factor 1; Cell Cycle Proteins; Flow Cytometry; G1 Phase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Male; NF-kappa B; Oligonucleotide Array Sequence Analysis; p300-CBP Transcription Factors; Prostatic Neoplasms; Proteins; Resveratrol; Stilbenes; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
Protective effect of trans-resveratrol on gentamicin-induced nephrotoxicity.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Antioxidants; Electrolytes; Gentamicins; Glomerular Filtration Rate; Hydro-Lyases; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Renal Circulation; Resveratrol; Stilbenes | 2002 |
Effect of red wine and wine polyphenol resveratrol on endothelial function in hypercholesterolemic rabbits.
Topics: Administration, Oral; Animals; Endothelin-1; Endothelium, Vascular; Hypercholesterolemia; Hypolipidemic Agents; Male; Nitric Oxide; Phenols; Rabbits; Resveratrol; Stilbenes; Vasodilation; Wine | 2003 |
[Studies on the inhibition of polyhydroxylated aromatic compounds against HIV-1 integrase].
Topics: Coumarins; HIV Integrase; HIV Integrase Inhibitors; HIV-1; Inhibitory Concentration 50; Naphthoquinones; Polycyclic Aromatic Hydrocarbons; Resveratrol; Stilbenes | 2002 |
Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice.
Topics: Administration, Topical; Animals; Antioxidants; Female; Hydrogen Peroxide; Lipid Peroxidation; Mice; Mice, Hairless; Prostaglandin-Endoperoxide Synthases; Radiation Injuries, Experimental; Resveratrol; Skin; Stilbenes; Ultraviolet Rays | 2003 |
Postharvest UV-C-irradiated grapes as a potential source for producing stilbene-enriched red wines.
Topics: Chromatography, High Pressure Liquid; Color; Fruit; Hydrogen-Ion Concentration; Mass Spectrometry; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis; Wine | 2003 |
Resveratrol content of Palomino fino grapes: influence of vintage and fungal infection.
Topics: Botrytis; Fruit; Plant Diseases; Resveratrol; Stilbenes; Vitis | 2003 |
Resveratrol acts as an estrogen receptor (ER) agonist in breast cancer cells stably transfected with ER alpha.
Topics: Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Receptors, Estrogen; Resveratrol; RNA, Messenger; Stilbenes; Transcriptional Activation; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2003 |
Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation.
Topics: Animals; Antioxidants; Ascorbic Acid; Cell Differentiation; Cell Division; Cells, Cultured; CHO Cells; Chromans; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; G2 Phase; Glutathione; Glutathione Disulfide; Mitosis; Oxidation-Reduction; Reactive Oxygen Species; Resting Phase, Cell Cycle; Resveratrol; S Phase; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue | 2003 |
Olive oil and red wine antioxidant polyphenols inhibit endothelial activation: antiatherogenic properties of Mediterranean diet phytochemicals.
Topics: Animals; Antioxidants; Arteriosclerosis; Cattle; Cell Adhesion; Cells, Cultured; Diet; Endothelium, Vascular; Flavonoids; Gene Expression Regulation; Humans; Iridoid Glucosides; Iridoids; NF-kappa B; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Oils; Polyphenols; Pyrans; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transcription, Genetic; U937 Cells; Vascular Cell Adhesion Molecule-1; Wine | 2003 |
Comparative characterization of peanuts grown by aquatic floating cultivation and field cultivation for seed and resveratrol production.
Topics: Agriculture; Arachis; Resveratrol; Seeds; Soil; Stilbenes; Temperature; Water | 2003 |
Oxidation of resveratrol catalyzed by soybean lipoxygenase.
Topics: Chromatography, High Pressure Liquid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Lipoxygenase; Lipoxygenase Inhibitors; Oxidation-Reduction; Resveratrol; Stilbenes | 2003 |
The bactericidal effects of Lactobacillus acidophilus, garcinol and Protykin compared to clarithromycin, on Helicobacter pylori.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antioxidants; Cell Division; Clarithromycin; Coculture Techniques; Dose-Response Relationship, Drug; Helicobacter pylori; Lactobacillus acidophilus; Resveratrol; Stilbenes; Terpenes; Time Factors | 2003 |
Distribution of [14C]-trans-resveratrol, a cancer chemopreventive polyphenol, in mouse tissues after oral administration.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Autoradiography; Biological Availability; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Male; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes; Tissue Distribution | 2003 |
Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.
Topics: Adenosine Triphosphate; Casein Kinase II; COP9 Signalosome Complex; Curcumin; Dichlororibofuranosylbenzimidazole; DNA-Binding Proteins; Emodin; Enzyme Inhibitors; Erythrocytes; HeLa Cells; Humans; Multiprotein Complexes; Peptide Hydrolases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Subunits; Proteins; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Resveratrol; Signal Transduction; Stilbenes; Substrate Specificity; Tumor Suppressor Protein p53; Ubiquitins | 2003 |
Low dose effects of bisphenol A on sexual differentiation of the brain and behavior in rats.
Topics: Animals; Benzhydryl Compounds; Brain; Diethylstilbestrol; Disorders of Sex Development; Drug Administration Schedule; Exploratory Behavior; Female; Male; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Resveratrol; Sexual Behavior, Animal; Stilbenes | 2003 |
Genome-scale analysis of resveratrol-induced gene expression profile in human ovarian cancer cells using a cDNA microarray.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Nucleus; DNA, Complementary; Female; Gene Expression Regulation, Neoplastic; Genome; Humans; NAD(P)H Dehydrogenase (Quinone); Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes; Time Factors; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Resveratrol induces apoptosis in human esophageal carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Esophageal Neoplasms; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2003 |
Estrogenic activity in white and red wine extracts.
Topics: Animals; beta-Galactosidase; Breast Neoplasms; CHO Cells; Cricetinae; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Gene Expression; Genes, Reporter; Humans; Plant Extracts; Receptors, Estrogen; Response Elements; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Tamoxifen; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Vitis; Wine | 2003 |
Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells.
Topics: Animals; Antimutagenic Agents; Blood Proteins; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; DNA Replication; Gamma Rays; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Retinoblastoma Protein; Ribosomal Protein S6 Kinases, 70-kDa; S Phase; Serine; Stilbenes; Transcription, Genetic; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2003 |
Resveratrol provides late-phase cardioprotection by means of a nitric oxide- and adenosine-mediated mechanism.
Topics: Adenosine; Animals; Cardiotonic Agents; Coronary Circulation; Enzyme Inhibitors; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Theophylline; Time Factors; Vasodilator Agents | 2003 |
Resveratrol, a red wine constituent polyphenol, prevents superoxide-dependent inflammatory responses induced by ischemia/reperfusion, platelet-activating factor, or oxidants.
Topics: Animals; Antioxidants; Cell Adhesion; Flavonoids; Free Radicals; Hypoxanthine; Inflammation; Leukocytes; Leukotriene B4; Male; Oxidants; Phenols; Platelet Activating Factor; Polyphenols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Time Factors; Xanthine Oxidase | 2003 |
Upregulation and activation of eNOS by resveratrol.
Topics: Antioxidants; Cardiotonic Agents; Enzyme Activation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Up-Regulation; Wine | 2003 |
Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Ascorbic Acid; Catechin; Chromium; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Hydrogen Peroxide; Inhibitory Concentration 50; Iron; Melatonin; Oxidative Stress; Resveratrol; Stilbenes; Thioctic Acid; Xanthurenates | 2003 |
Resveratrol-induced G2 arrest through the inhibition of CDK7 and p34CDC2 kinases in colon carcinoma HT29 cells.
Topics: Antineoplastic Agents; cdc25 Phosphatases; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; G2 Phase; HT29 Cells; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2003 |
Resveratrol-induced modification of polyamine metabolism is accompanied by induction of c-Fos.
Topics: Acetyltransferases; Adenocarcinoma; Adenosylmethionine Decarboxylase; Anticarcinogenic Agents; Base Sequence; Caco-2 Cells; Catechin; Colonic Neoplasms; DNA Primers; Gene Expression Regulation; Humans; Ornithine Decarboxylase; Polyamines; Proto-Oncogene Proteins c-fos; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2003 |
In vitro assessment of inhibition by natural polyphenols of metabolic activation of procarcinogens by human CYP1A1.
Topics: Anticarcinogenic Agents; Benzo(a)pyrene; Biotransformation; Carcinogens; Catechin; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Flavonoids; Humans; In Vitro Techniques; Phenols; Polymers; Resveratrol; Stilbenes | 2003 |
Oral administration of trans-resveratrol to guinea pigs increases cardiac DT-diaphorase and catalase activities, and protects isolated atria from menadione toxicity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Catalase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; NAD(P)H Dehydrogenase (Quinone); Reactive Oxygen Species; Resveratrol; Stilbenes; Subcellular Fractions; Superoxide Dismutase; Vitamin K 3 | 2003 |
Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Death; Cell Nucleus; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; In Situ Nick-End Labeling; Membrane Potentials; Microscopy, Fluorescence; Mitochondria; NF-kappa B; Oxidative Stress; Oxygen; PC12 Cells; Peroxides; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Tetrazolium Salts; Thiazoles | 2003 |
[Effects of resveratrol on Ca2+, Mg(2+)-ATPase activities after spinal cord trauma in rats].
Topics: Animals; Ca(2+) Mg(2+)-ATPase; Drugs, Chinese Herbal; Female; Male; Methylprednisolone; Rats; Rats, Sprague-Dawley; Resveratrol; Spinal Cord Injuries; Stilbenes | 2002 |
Inhibition of cell transformation by resveratrol and its derivatives: differential effects and mechanisms involved.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Epidermal Growth Factor; G1 Phase; Gene Expression Regulation; Genes, p53; Mice; Resveratrol; Stilbenes | 2003 |
Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.
Topics: Acute Disease; Aged; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow; Cell Division; Female; Humans; Interleukin-1; Leukemia, Myeloid; Male; Middle Aged; NF-kappa B; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured | 2003 |
p21Cip1 gene expression is modulated by Egr1: a novel regulatory mechanism involved in the resveratrol antiproliferative effect.
Topics: Cell Differentiation; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA-Binding Proteins; Early Growth Response Protein 1; Erythroid Precursor Cells; Gene Expression Regulation; Globins; Humans; Immediate-Early Proteins; K562 Cells; Promoter Regions, Genetic; Resveratrol; Stilbenes; Transcription Factors; Transcriptional Activation | 2003 |
Glycosylation of resveratrol protects it from enzymic oxidation.
Topics: Biotransformation; Flavonoids; Fruit; Glycosylation; Kinetics; Molecular Conformation; Molecular Structure; Monophenol Monooxygenase; Phenols; Polymers; Polyphenols; Resveratrol; Stilbenes | 2003 |
The egr-1 gene is induced by DNA-damaging agents and non-genotoxic drugs in both normal and neoplastic human cells.
Topics: Animals; Antineoplastic Agents; Cell Line; DNA; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Gene Expression Regulation; Genes, Reporter; Humans; Immediate-Early Proteins; MAP Kinase Signaling System; Mitomycin; Mutagens; Nucleic Acid Synthesis Inhibitors; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Resveratrol; Stilbenes; Topotecan; Transcription Factors; Tumor Suppressor Protein p53; Zinc Fingers | 2003 |
Phytoestrogen regulation of a Vitamin D3 receptor promoter and 1,25-dihydroxyvitamin D3 actions in human breast cancer cells.
Topics: Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Blotting, Western; Breast Neoplasms; Calcitriol; Cell Cycle; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal; Flow Cytometry; Genes, Reporter; Genistein; Humans; Isoflavones; Phytoestrogens; Plant Preparations; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Receptors, Calcitriol; Resveratrol; Stilbenes; Tamoxifen; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Up-Regulation | 2003 |
Different short- and long-term effects of resveratrol on nuclear factor-kappaB phosphorylation and nuclear appearance in human endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; NF-kappa B; NF-kappa B p50 Subunit; Phosphorylation; Resveratrol; Serine; Signal Transduction; Stilbenes; Transcription Factor RelA; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Resveratrol transport and metabolism by human intestinal Caco-2 cells.
Topics: Absorption; Biological Transport; Biotransformation; Caco-2 Cells; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Platelet Aggregation Inhibitors; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2003 |
Resveratrol induces downregulation in survivin expression and apoptosis in HTLV-1-infected cell lines: a prospective agent for adult T cell leukemia chemotherapy.
Topics: Adult; Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line; Cysteine Proteinase Inhibitors; Down-Regulation; Flow Cytometry; Gene Expression; HTLV-I Infections; Humans; Inhibitor of Apoptosis Proteins; Leukemia-Lymphoma, Adult T-Cell; Microtubule-Associated Proteins; Neoplasm Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Survivin | 2002 |
Synthesis and evaluation of cytotoxicity of stilbene analogues.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Phytoalexins; Plant Extracts; Resveratrol; Sesquiterpenes; Stilbenes; Structure-Activity Relationship; Terpenes; Tumor Cells, Cultured | 2003 |
Effects of p-nonylphenol and resveratrol on body and organ weight and in vivo fertility of outbred CD-1 mice.
Topics: Acrosome; Animals; Animals, Outbred Strains; Body Weight; Environmental Pollutants; Female; Fertility; Genitalia, Female; Genitalia, Male; Infertility, Male; Isoflavones; Kidney; Litter Size; Liver; Male; Mice; Organ Size; Ovarian Follicle; Phenols; Phytoestrogens; Plant Preparations; Pregnancy; Resveratrol; Sex Ratio; Spermatogenesis; Stilbenes | 2003 |
Density functional theory calculations for resveratrol.
Topics: Antioxidants; Free Radicals; Models, Chemical; Molecular Structure; Oxidation-Reduction; Resveratrol; Stilbenes; Structure-Activity Relationship; Thermodynamics | 2003 |
Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol.
Topics: Adult; Axilla; Cosmetics; Cross Reactions; Dermatitis, Allergic Contact; Diagnosis, Differential; Glycols; Groin; Humans; Male; Patch Tests; Pentanes; Resveratrol; Stilbenes | 2003 |
Differential effects of quercetin and resveratrol on Band 3 tyrosine phosphorylation signalling of red blood cells.
Topics: Anion Exchange Protein 1, Erythrocyte; Antioxidants; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Precursors; Erythrocyte Membrane; Erythrocytes; Humans; Intracellular Signaling Peptides and Proteins; Peroxynitrous Acid; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quercetin; Resveratrol; Signal Transduction; src-Family Kinases; Stilbenes; Syk Kinase; Tyrosine | 2003 |
Suppression of IL-8 gene transcription by resveratrol in phorbol ester treated human monocytic cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Electrophoretic Mobility Shift Assay; Humans; Interleukin-8; NF-kappa B; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; U937 Cells | 2003 |
Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzyl Alcohols; Cell Line; Coumarins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Induction; Enzyme Inhibitors; Flavones; Flavonoids; Food; Gene Expression Regulation; Genistein; I-kappa B Proteins; Interferon-gamma; Isoenzymes; Isothiocyanates; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Transcription Factor RelA | 2003 |
Enhanced MTT-reducing activity under growth inhibition by resveratrol in CEM-C7H2 lymphocytic leukemia cells.
Topics: Antioxidants; Apoptosis; Artifacts; Cell Division; Colorimetry; Dose-Response Relationship, Drug; Electron Transport; Formazans; Growth Inhibitors; Histocytochemistry; Humans; Indicators and Reagents; Leukemia, T-Cell; Mitochondria; NAD; NADP; Organ Specificity; Oxidation-Reduction; Resveratrol; Stilbenes; Subcellular Fractions; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2003 |
Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Antineoplastic Agents, Phytogenic; Arachidonic Acids; Breast Neoplasms; Cell Division; Cyclic AMP; Cyclic GMP; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; Receptors, Estrogen; Resveratrol; Rolipram; Stilbenes; Tamoxifen; Tumor Cells, Cultured | 2003 |
[Studies on chemical constituents of oligostilbenes from Vitis davidii Foex].
Topics: Benzofurans; Phenols; Plants, Medicinal; Resveratrol; Stilbenes; Vitis | 2001 |
Nanomolar level of resveratrol (trans-3,5,4'-trihydroxystilbene) is required, but is not sufficient, to inhibit the growth of human monocytoid tumor cells through an apoptotic-like mechanism.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Fluorescent Antibody Technique; Humans; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Monocytes; Resveratrol; Stilbenes; U937 Cells | 2002 |
[Resveratrol promote permeability transition pore opening mediated by Ca2+].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Female; Ion Channels; Membrane Potentials; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2003 |
Neuraminidase inhibitors from Reynoutria elliptica.
Topics: Drugs, Chinese Herbal; Emodin; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Neuraminidase; Polygonaceae; Resveratrol; Stilbenes; Structure-Activity Relationship | 2003 |
Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes.
Topics: Antioxidants; Catalase; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Glutathione Reductase; Glutathione Transferase; Hexylresorcinol; Humans; Hydrogen Peroxide; Lymphocytes; Oxidants; Oxidation-Reduction; Peroxidases; Resveratrol; Stilbenes; Time Factors | 2003 |
Effects of resveratrol on lymphocyte proliferation and cytokine release.
Topics: Adult; Animals; Antioxidants; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Humans; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Phytohemagglutinins; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2003 |
Resveratrol and red wine extracts inhibit the growth of CagA+ strains of Helicobacter pylori in vitro.
Topics: Adenocarcinoma; Amoxicillin; Antigens, Bacterial; Antineoplastic Agents, Phytogenic; Bacterial Proteins; Chemoprevention; Gastrointestinal Neoplasms; Helicobacter pylori; Humans; Penicillins; Phenols; Plant Extracts; Resveratrol; Stilbenes; Wine | 2003 |
Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages.
Topics: Alcoholic Beverages; Benzofurans; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Microsomes, Liver; Phenols; Plant Extracts; Polymers; Polyphenols; Resveratrol; Stilbenes | 2003 |
The effect of plant phenolics on the formation of 7,12-dimethylbenz[a]anthracene-DNA adducts and TPA-stimulated polymorphonuclear neutrophils chemiluminescence in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chlorogenic Acid; DNA; DNA Adducts; Enzyme Inhibitors; Humans; Hydrolyzable Tannins; Hydroxybenzoates; Luminescent Measurements; Male; Methylcholanthrene; Neutrophils; Phenols; Rats; Rats, Wistar; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2003 |
Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines.
Topics: Anticarcinogenic Agents; BRCA1 Protein; BRCA2 Protein; Breast Neoplasms; DNA Primers; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2003 |
Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Division; Colonic Neoplasms; Enzyme Activation; Humans; Membrane Potentials; Mitochondria; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2003 |
Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats.
Topics: Animals; Antioxidants; Cell Division; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Dose-Response Relationship, Drug; Fruit; Hypolipidemic Agents; Lipid Peroxides; Lipids; Liver; Liver Neoplasms, Experimental; Male; Neoplasm Metastasis; Neoplasm Transplantation; Rats; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Triglycerides; Tumor Cells, Cultured; Vitis; Wine | 2003 |
Effects of resveratrol on secondary damages after acute spinal cord injury in rats.
Topics: Acute Disease; Animals; Edema; Female; L-Lactate Dehydrogenase; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Stilbenes | 2003 |
Potential mechanism by which resveratrol, a red wine constituent, protects neurons.
Topics: Animals; Antioxidants; Cells, Cultured; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Mice; Molecular Structure; Neurons; Neuroprotective Agents; Phenols; Resveratrol; Stilbenes; Wine | 2003 |
Antitumor and immunomodulatory activity of resveratrol on experimentally implanted tumor of H22 in Balb/c mice.
Topics: Adjuvants, Immunologic; Animals; Antibody-Producing Cells; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Erythrocytes; Immunoglobulin G; Liver Neoplasms, Experimental; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Resveratrol; Sheep; Stilbenes; Tumor Necrosis Factor-alpha | 2003 |
Resveratrol and quercetin down-regulate tissue factor expression by human stimulated vascular cells.
Topics: Active Transport, Cell Nucleus; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Humans; I-kappa B Proteins; Monocytes; Proto-Oncogene Proteins c-rel; Quercetin; Resveratrol; Stilbenes; Thromboplastin; Umbilical Veins; Wine | 2003 |
Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agents.
Topics: Antineoplastic Agents; Apoptosis; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Isomerism; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Functional evaluation of novel single nucleotide polymorphisms and haplotypes in the promoter regions of CYP1B1 and CYP1A1 genes.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Primers; Gene Expression Regulation, Enzymologic; Genotype; Haplotypes; Humans; Luciferases; Lung Neoplasms; Mutagenesis, Site-Directed; Mutation; Polycyclic Aromatic Hydrocarbons; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Resveratrol; Ribonucleotide Reductases; Stilbenes; White People | 2003 |
[The neuroprotection of resveratrol in the experimental cerebral ischemia].
Topics: Animals; Brain Edema; Brain Ischemia; Male; Neuroprotective Agents; NF-kappa B; Rats; Rats, Wistar; Resveratrol; Stilbenes; Transcription Factor RelA | 2003 |
Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cell Line, Tumor; Colonic Neoplasms; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Flow Cytometry; Genes, Dominant; Genetic Vectors; Humans; Immunoblotting; Ligands; Lipid Metabolism; Membrane Glycoproteins; Membrane Microdomains; Microscopy, Fluorescence; Mitochondria; Precipitin Tests; Protein Conformation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Transfection | 2003 |
Effects of dietary antioxidants and 2-amino-3-methylimidazo[4,5-f]- quinoline (IQ) on preneoplastic lesions and on oxidative damage, hormonal status, and detoxification capacity in the rat.
Topics: Animals; Antioxidants; Biomarkers; Carotenoids; Colon; Comet Assay; Diet; Glutathione Transferase; Hormones; Immunohistochemistry; Liver; Lycopene; Male; Oxidation-Reduction; Oxidative Stress; Placenta; Precancerous Conditions; Quercetin; Quinolines; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2003 |
Inhibitory effects of resveratrol derivatives from dipterocarpaceae plants on tyrosinase activity.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Ericales; Mice; Molecular Structure; Monophenol Monooxygenase; Pyrones; Resveratrol; Stilbenes; Structure-Activity Relationship | 2003 |
Resveratrol modulates apoptosis and oxidation in human blood mononuclear cells.
Topics: Antioxidants; Apoptosis; Cell Membrane Permeability; Cells, Cultured; Culture Media; gamma-Glutamyltransferase; Glutathione Transferase; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes | 2003 |
Direct HPLC analysis of quercetin and trans-resveratrol in red wine, grape, and winemaking byproducts.
Topics: Chromatography, High Pressure Liquid; Fruit; Quercetin; Resveratrol; Stilbenes; Vitis; Wine | 2003 |
Resveratrol and non-ethanolic components of wine in experimental cardiology.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Humans; Resveratrol; Stilbenes; Wine | 2003 |
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Topics: Acetylation; Caloric Restriction; Catalysis; Cell Line; Cell Survival; Cellular Senescence; Flavonoids; Histone Deacetylases; Humans; Kinetics; Longevity; Phenols; Polymers; Polyphenols; Recombination, Genetic; Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes; Tumor Suppressor Protein p53; Wine | 2003 |
Differentiation-dependent levels of benzofuran-type resveratrol dimers in root cultures of Anigozanthos preissii.
Topics: Benzofurans; Dimerization; Magnetic Resonance Spectroscopy; Magnoliopsida; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Resveratrol; Stilbenes | 2003 |
Longevity research. In vino vitalis? Compounds activate life-extending genes.
Topics: Aging; Animals; Caloric Restriction; Flavonoids; Gene Expression Regulation; Histone Deacetylases; Humans; Longevity; Phenols; Polymers; Polyphenols; Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes; Vitis; Wine | 2003 |
Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Caco-2 Cells; Cell Cycle; Cell Division; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gout Suppressants; Humans; Microtubules; Mitosis; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Polymers; Resveratrol; Stilbenes; Tubulin; Tubulin Modulators; Vinblastine | 2003 |
Comparative analysis of the phenolic content of selected Chilean, Canadian and American Merlot red wines.
Topics: Antioxidants; Canada; Catechin; Chile; Chromatography, High Pressure Liquid; Phenols; Quercetin; Resveratrol; Rutin; Stilbenes; United States; Wine | 2003 |
Involvement of p21WAF1/CIP1, pRB, Bax and NF-kappaB in induction of growth arrest and apoptosis by resveratrol in human lung carcinoma A549 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspases; Cell Cycle; Cell Death; Cell Division; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Models, Biological; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Retinoblastoma Protein; S Phase; Stilbenes; Time Factors; Transcription, Genetic; Transfection; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
Resveratrol suppresses growth of Ishikawa cells through down-regulation of EGF.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Epidermal Growth Factor; Female; Humans; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors | 2003 |
Ageing: a toast to long life.
Topics: Acetylation; Animals; Caloric Restriction; Flavonoids; Histone Deacetylases; Humans; Longevity; NAD; Phenols; Polymers; Polyphenols; Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes; Wine | 2003 |
Resveratrol in raw and baked blueberries and bilberries.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Fruit; Hot Temperature; Mass Spectrometry; Resveratrol; Stilbenes; Vaccinium; Vaccinium myrtillus | 2003 |
Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses.
Topics: Animals; Cell Line; Chromium; DNA Damage; Electron Spin Resonance Spectroscopy; Lipid Peroxidation; Mice; NF-kappa B; Reactive Oxygen Species; Resveratrol; Stilbenes | 2003 |
Estrogen receptor beta isoforms exhibit differences in ligand-activated transcriptional activity in an estrogen response element sequence-dependent manner.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetinae; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Humans; Isomerism; Ligands; Rats; Receptors, Estrogen; Response Elements; Resveratrol; Stilbenes; Transcriptional Activation; Transfection | 2004 |
Resveratrol and two monomethylated stilbenes from Israeli Rumex bucephalophorus and their antioxidant potential.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Israel; Molecular Structure; Plant Roots; Plants, Medicinal; Resveratrol; Rumex; Stilbenes | 2003 |
[Inhibition of dexamethasone, indomethacin and resveratrol on matrix metalloproteinase-9 and the mechanism of inhibition].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Croton Oil; Dexamethasone; Ear Diseases; Edema; Humans; Indomethacin; Male; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred ICR; Random Allocation; Resveratrol; Stilbenes; U937 Cells | 2003 |
Effect of ochratoxin A-producing Aspergilli on stilbenic phytoalexin synthesis in grapes.
Topics: Aspergillus; Fruit; Kinetics; Ochratoxins; Phytoalexins; Plant Extracts; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Vitis | 2003 |
Membrane-rigidifying effects of anti-cancer dietary factors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apigenin; Catechin; Cell Division; Cell Membrane; Diet; Flavonoids; Fluorescence Polarization; Genistein; Isoflavones; Liposomes; Membrane Fluidity; Membrane Lipids; Mice; Multiple Myeloma; Phenols; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2002 |
Effect of resveratrol on some activities of isolated and in whole blood human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis; Dose-Response Relationship, Drug; Humans; Hypochlorous Acid; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitrites; Resveratrol; Stilbenes; Superoxides; Zymosan | 2003 |
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol.
Topics: Acyltransferases; Antioxidants; Coenzyme A Ligases; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Transformation, Genetic; Wine | 2003 |
Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; CDC2 Protein Kinase; Cell Cycle Proteins; Cyclin B; Cyclin B1; Cyclin D1; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Resveratrol; Stilbenes | 2003 |
Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling.
Topics: Acyltransferases; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Division; Cell Line, Tumor; Ceramides; Enzyme Inhibitors; Female; Humans; Models, Biological; Neoplasm Metastasis; Resveratrol; Serine C-Palmitoyltransferase; Signal Transduction; Sphingomyelins; Stilbenes | 2003 |
Inhibition of vascular endothelial growth factor-induced angiogenesis by resveratrol through interruption of Src-dependent vascular endothelial cadherin tyrosine phosphorylation.
Topics: Antigens, CD; Antioxidants; Cadherins; Cell Division; Cell Movement; Cells, Cultured; CSK Tyrosine-Protein Kinase; Drug Interactions; Endothelium, Vascular; Humans; Neovascularization, Physiologic; Phosphorylation; Protein-Tyrosine Kinases; Resveratrol; src-Family Kinases; Stilbenes; Tyrosine; Vascular Endothelial Growth Factor A | 2003 |
Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Survival; Cerebellar Neoplasms; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Humans; Medulloblastoma; Membrane Glycoproteins; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2003 |
Profound negative regulatory effects by resveratrol on vascular smooth muscle cells: a role of p53-p21(WAF1/CIP1) pathway.
Topics: Aorta; Apoptosis; Cell Division; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Replication; Dose-Response Relationship, Drug; Humans; Muscle, Smooth, Vascular; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2003 |
ROS are required for rapid reactivation of Na+/Ca2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes.
Topics: Animals; Antioxidants; Cells, Cultured; Chromans; Diazoxide; Free Radical Scavengers; Guinea Pigs; Heart Ventricles; Hypoxia; Metalloporphyrins; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sodium-Calcium Exchanger; Stilbenes | 2004 |
Effects of resveratrol on acoustic trauma.
Topics: Animals; Antioxidants; Auditory Threshold; Cochlea; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Noise-Induced; Male; Oxidative Stress; Random Allocation; Rats; Rats, Inbred F344; Reactive Oxygen Species; Resveratrol; Stilbenes | 2003 |
Synergistic protection of PC12 cells from beta-amyloid toxicity by resveratrol and catechin.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Cell Count; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Lipid Peroxidation; PC12 Cells; Peptide Fragments; Rats; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Thiobarbiturates | 2003 |
Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility.
Topics: Alprostadil; Animals; Aspirin; Cell Membrane; Cryopreservation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Male; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Resveratrol; Semen; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes; Sulfonamides; Tolmetin; Turkeys | 2003 |
Drinking your health? It's too early to say.
Topics: Diet; Health; Humans; Longevity; Models, Biological; Reproducibility of Results; Resveratrol; Stilbenes; Wine; Yeasts | 2003 |
Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: effect on nitrosative and oxidative stress derived from microglial cells.
Topics: Animals; Antioxidants; Biphenyl Compounds; Blotting, Western; Cells, Cultured; Fluorescein; Fluoresceins; Free Radical Scavengers; Hydrazines; Mice; Microglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Picrates; Plant Extracts; Rats; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2003 |
Inhibition of cyclic strain-induced endothelin-1 gene expression by resveratrol.
Topics: Antioxidants; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Mitogen-Activated Protein Kinases; NADPH Oxidases; Periodicity; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Stress, Mechanical; Transcription Factor AP-1; Transcription, Genetic | 2003 |
Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor alpha in mice.
Topics: Animals; Brain; Cattle; Dose-Response Relationship, Drug; Fenofibrate; Haplorhini; Humans; Mice; Mice, Knockout; Receptors, Cytoplasmic and Nuclear; Resveratrol; Stilbenes; Stroke; Transcription Factors | 2003 |
Resveratrol inhibits matrix metalloproteinase-9 transcription in U937 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Humans; Matrix Metalloproteinase 9; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transcription, Genetic; U937 Cells | 2003 |
Immunomodulatory activity of resveratrol: discrepant in vitro and in vivo immunological effects.
Topics: Animals; Antioxidants; Cell Division; Cytokines; Hematopoietic Stem Cells; Immunity; Interferon-gamma; Interleukin-12; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred C3H; Resveratrol; Stilbenes | 2003 |
Possible role of cell surface H+ -ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells.
Topics: Adenosine Triphosphate; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Division; Cell Line; Cell Membrane; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Precursors; Extracellular Space; Humans; Intracellular Signaling Peptides and Proteins; Oligomycins; Peptides; Potassium Cyanide; Protein-Tyrosine Kinases; Proton-Translocating ATPases; Resveratrol; Ribonucleotide Reductases; Stilbenes; Syk Kinase; Umbilical Veins | 2003 |
Prepubertal resveratrol exposure accelerates N-methyl-N-nitrosourea-induced mammary carcinoma in female Sprague-Dawley rats.
Topics: Age Factors; Alkylating Agents; Animals; Body Weight; Dose-Response Relationship, Drug; Estrous Cycle; Female; Isoflavones; Mammary Neoplasms, Experimental; Methylnitrosourea; Phytoestrogens; Plant Preparations; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2003 |
Red wine, resveratrol, Chlamydia pneumoniae and the French connection.
Topics: Azithromycin; Chlamydophila Infections; Chlamydophila pneumoniae; Coronary Artery Disease; Female; France; Humans; Male; Microbial Sensitivity Tests; Platelet Aggregation Inhibitors; Primary Prevention; Prognosis; Resveratrol; Risk Assessment; Stilbenes; United States; Wine | 2003 |
[Quantitative analysis of resveratrol from grape seeds and grape skins by high performance liquid chromatography method].
Topics: Chromatography, High Pressure Liquid; Resveratrol; Seeds; Stilbenes; Vitis | 2003 |
Modeling the co-antioxidant behavior of monofunctional phenols. Applications to some relevant compounds.
Topics: alpha-Tocopherol; Antioxidants; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Models, Chemical; Phenols; Resveratrol; Stilbenes; Thermodynamics | 2003 |
Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC delta signal transduction.
Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Cell Line, Tumor; Cloning, Molecular; DNA Primers; Female; Gene Expression Regulation, Enzymologic; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Plasmids; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-delta; Resveratrol; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection; Uterine Cervical Neoplasms | 2004 |
Inhibitory effect of resveratrol on angiotensin II-induced cardiomyocyte hypertrophy.
Topics: Acetylcysteine; Angiotensin II; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Hypertrophy; Leucine; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myosin Heavy Chains; Phosphorylation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection; Ventricular Myosins | 2004 |
Inhibition of osteoclast formation by 3-methylcholanthrene, a ligand for arylhydrocarbon receptor: suppression of osteoclast differentiation factor in osteogenic cells.
Topics: Animals; Carcinogens; Carrier Proteins; Drug Interactions; Male; Membrane Glycoproteins; Methylcholanthrene; Mice; Osteoclasts; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2004 |
Effect of topically applied resveratrol on cutaneous herpes simplex virus infections in hairless mice.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Drug Resistance, Viral; Fatty Alcohols; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Resveratrol; Stilbenes | 2004 |
Nonaqueous capillary electrophoretic separation of polyphenolic compounds in wine using coated capillaries at high pH in methanol.
Topics: Chemical Phenomena; Chemistry, Physical; Coated Materials, Biocompatible; Electrophoresis, Capillary; Flavonoids; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Methanol; Resveratrol; Stilbenes; Wine | 2003 |
Syntheses and radical scavenging activities of resveratrol derivatives.
Topics: Antioxidants; Free Radical Scavengers; Resveratrol; Stilbenes | 2004 |
Dietary resveratrol does not affect intestinal tumorigenesis in Apc(Min/+) mice.
Topics: Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Diet; Dinoprostone; Glucuronides; Intestinal Neoplasms; Isoenzymes; Kinetics; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes | 2004 |
Grape polyphenol resveratrol and the related molecule 4-hydroxystilbene induce growth inhibition, apoptosis, S-phase arrest, and upregulation of cyclins A, E, and B1 in human SK-Mel-28 melanoma cells.
Topics: Apoptosis; Cell Cycle; Cell Division; Cyclin A; Cyclin B; Cyclin B1; Cyclin E; Cyclins; Fruit; Humans; Melanoma; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured; Vitis | 2003 |
Antifungal activity of stilbenes in in vitro bioassays and in transgenic Populus expressing a gene encoding pinosylvin synthase.
Topics: Acyltransferases; Agrobacterium tumefaciens; Antifungal Agents; Fungi; Gene Expression; Plants, Genetically Modified; Populus; Resveratrol; Stilbenes; Transformation, Genetic | 2004 |
Resveratrol inhibits cell proliferation and induces apoptosis of human breast carcinoma MCF-7 cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Primers; Female; Humans; Neoplasm Proteins; Phytotherapy; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Vitis; Wine | 2004 |
Constitutive expression of CYP1A1 in bovine cumulus oocyte-complexes in vitro: mechanisms and biological implications.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Blood; Cattle; Cellular Senescence; Cytochrome P-450 CYP1A1; DNA-Binding Proteins; Female; Gene Expression; Oocytes; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Transcription Factors | 2004 |
Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol.
Topics: Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Brain Neoplasms; Breast Neoplasms; Caspase Inhibitors; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cysteine Proteinase Inhibitors; DNA Primers; Female; Humans; Male; Melanoma; Membrane Glycoproteins; Pancreatic Neoplasms; Prostatic Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2004 |
Determination of phenolic constituents of biological interest in red wine by capillary electrophoresis with electrochemical detection.
Topics: Catechin; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Phenols; Reproducibility of Results; Resveratrol; Stilbenes; Wine | 2004 |
Resveratrol antagonizes EGFR-dependent Erk1/2 activation in human androgen-independent prostate cancer cells with associated isozyme-selective PKC alpha inhibition.
Topics: Androgens; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Isoenzymes; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Kinase C; Protein Kinase C-alpha; Resveratrol; Stilbenes | 2004 |
Resveratrol-induced autophagocytosis in ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Female; Humans; Kinetics; Microscopy, Fluorescence; Ovarian Neoplasms; Plasmids; Resveratrol; Stilbenes | 2004 |
Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; bcl-X Protein; Caspases; Cell Cycle; Cell Line, Tumor; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; G2 Phase; Humans; Immunoblotting; Intracellular Membranes; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Membrane Potentials; Mitochondria; Models, Biological; Multiple Myeloma; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Time Factors; Transcription Factor AP-1 | 2004 |
Resveratrol derivatives potently induce apoptosis in human promyelocytic leukemia cells.
Topics: Apoptosis; Aryl Hydrocarbon Hydroxylases; Cell Cycle; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Flow Cytometry; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia; Resveratrol; RNA, Messenger; Stilbenes | 2003 |
Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation.
Topics: Antioxidants; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Glycogen Synthase Kinase 3; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Polymerase Chain Reaction; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Resveratrol; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2004 |
Isorhapontigenin and resveratrol suppress oxLDL-induced proliferation and activation of ERK1/2 mitogen-activated protein kinases of bovine aortic smooth muscle cells.
Topics: Animals; Anticarcinogenic Agents; Aorta; Cattle; Cell Division; Cells, Cultured; Enzyme Activation; Hydrogen Peroxide; Lipoproteins, LDL; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Resveratrol; Signal Transduction; Stilbenes | 2004 |
In Methuselah's Mould.
Topics: Aging; Animals; Diet; Flavonoids; Humans; Longevity; Phenols; Polyphenols; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2004 |
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Chemoprevention; Colorectal Neoplasms; Drug Design; Hydroxylation; Isomerism; Mice; Resveratrol; Stilbenes; Tissue Distribution | 2004 |
Styrylquinazolines: a new class of inhibitors on prostaglandin E2 production in lipopolysaccharide-activated macrophage cells.
Topics: Cell Line; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation, Enzymologic; Isoenzymes; Lipopolysaccharides; Macrophage Activation; Macrophages; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Quinazolines; Resveratrol; Stilbenes; Styrenes | 2004 |
Phenylpropanoid glycosides from Orobanche caerulescens.
Topics: Adult; Antioxidants; Cholesterol, LDL; Glucosides; Glycosides; Humans; Inhibitory Concentration 50; Lipid Peroxidation; Male; Orobanche; Phenols; Phytotherapy; Plant Components, Aerial; Plant Extracts; Resveratrol; Stilbenes | 2004 |
Differential recognition of resveratrol isomers by the human estrogen receptor-alpha: molecular dynamics evidence for stereoselective ligand binding.
Topics: Binding Sites; Estrogen Receptor alpha; Humans; In Vitro Techniques; Isoflavones; Ligands; Models, Molecular; Phytoestrogens; Plant Preparations; Receptors, Estrogen; Resveratrol; Stereoisomerism; Stilbenes; Thermodynamics | 2004 |
Urinary and plasma levels of resveratrol and quercetin in humans, mice, and rats after ingestion of pure compounds and grape juice.
Topics: Animals; Antineoplastic Agents; Antioxidants; Beverages; Biological Availability; Fruit; Humans; Mice; Quercetin; Rats; Resveratrol; Stilbenes; Vitis | 2004 |
Resveratrol, a red wine constituent polyphenol, protects from ischemia-reperfusion damage of the ovaries.
Topics: Animals; Antioxidants; Female; Flavonoids; Ovarian Diseases; Ovary; Phenols; Phytotherapy; Polyphenols; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes; Torsion Abnormality; Vitis; Wine | 2004 |
Resveratrol inhibits drug-induced apoptosis in human leukemia cells by creating an intracellular milieu nonpermissive for death execution.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Daunorubicin; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia; Mitochondria; NADPH Oxidases; Oxidation-Reduction; Resveratrol; Stilbenes; Superoxides; Vincristine | 2004 |
Antiproliferative effect of resveratrol in human prostate carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Caspases; Cell Division; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Humans; Male; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation | 2003 |
A mechanistic study on the nuclease activities of some hydroxystilbenes.
Topics: Catechols; Copper; Deoxyribonucleases; DNA; DNA Damage; Oxidation-Reduction; Oxygen; Plasmids; Resorcinols; Resveratrol; Stilbenes; Structure-Activity Relationship; Superoxides | 2004 |
On-line identification of trans-resveratrol in red wine using a sweeping technique combined with capillary electrophoresis/77 K fluorescence spectroscopy.
Topics: Anticarcinogenic Agents; Chromatography, Micellar Electrokinetic Capillary; Cold Temperature; Cryopreservation; Flow Injection Analysis; Isomerism; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Wine | 2004 |
Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Hypoxanthine; Interferon-gamma; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Stilbenes; Xanthine Oxidase | 2004 |
Comparative study of estrogenic potencies of estradiol, tamoxifen, bisphenol-A and resveratrol with two in vitro bioassays.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Benzhydryl Compounds; Biological Assay; Estradiol; Estrogens, Non-Steroidal; Immunoenzyme Techniques; Phenols; Receptors, Estrogen; Resveratrol; Sensitivity and Specificity; Stilbenes; Tamoxifen; Yeasts | 2004 |
Heyneanol A induces apoptosis via cytochrome c release and caspase activation in human leukemic U937 cells.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cytochromes c; DNA, Neoplasm; Enzyme Activation; G1 Phase; Humans; Mitochondria; Plant Roots; Poly(ADP-ribose) Polymerases; Resveratrol; Stilbenes; U937 Cells; Vitis | 2004 |
Scientific community. Aging research's family feud.
Topics: Aging; Animals; Australia; Biotechnology; Caloric Restriction; Histone Deacetylases; History, 20th Century; History, 21st Century; Humans; Longevity; NAD; Niacinamide; Nicotinamidase; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Stilbenes; United States | 2004 |
Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Creatine Kinase; Gene Expression; Heart Rate; L-Lactate Dehydrogenase; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2004 |
Interaction among phenols in food fortification: negative synergism on antioxidant capacity.
Topics: Antioxidants; Catechin; Drug Interactions; Ethanol; Food, Fortified; Phenols; Quercetin; Resveratrol; Solutions; Stilbenes | 2004 |
Resveratrol inhibits phenotypic and functional maturation of murine bone marrow-derived dendritic cells.
Topics: Animals; Antigens, CD; B7-1 Antigen; B7-2 Antigen; Bone Marrow Cells; Cell Differentiation; Dendritic Cells; Down-Regulation; Endocytosis; Immunosuppressive Agents; Interleukin-12; Lymphocyte Culture Test, Mixed; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes; T-Lymphocytes; Vitis | 2004 |
Correlation of sister chromatid exchange formation through homologous recombination with ribonucleotide reductase inhibition.
Topics: Alkylating Agents; Animals; CHO Cells; Cricetinae; Cricetulus; Crossing Over, Genetic; DNA Replication; Enzyme Inhibitors; Hydroxyurea; Mitomycin; Protein Subunits; Resveratrol; Ribonucleotide Reductases; Sister Chromatid Exchange; Stilbenes; Structure-Activity Relationship; Time Factors | 2004 |
Resveratrol, a polyphenol found in grapes, suppresses oxidative damage and stimulates apoptosis during early colonic inflammation in rats.
Topics: Animals; Antioxidants; Apoptosis; Colitis; Flavonoids; Inflammation; Male; Oxidative Stress; Phenols; Polyphenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vitis | 2004 |
Resveratrol is a peroxidase-mediated inactivator of COX-1 but not COX-2: a mechanistic approach to the design of COX-1 selective agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Binding Sites; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Hydroquinones; Inhibitory Concentration 50; Isoenzymes; Kinetics; Membrane Proteins; Models, Chemical; Oxygen; Peroxidase; Peroxidases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Resveratrol; Spectrophotometry; Stilbenes; Structure-Activity Relationship; Time Factors | 2004 |
Say yes to sirtuin; no to lamp shades.
Topics: Cellular Senescence; Enzyme Inhibitors; Humans; Resveratrol; Stilbenes; Wit and Humor as Topic | 2004 |
Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C.
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cytotoxins; Enzyme Activation; Female; Hippocampus; Neurons; Neuroprotective Agents; Peptide Fragments; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2004 |
Pro-oxidant activity of low doses of resveratrol inhibits hydrogen peroxide-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Caspases; HL-60 Cells; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Oxidants; Resveratrol; Stilbenes; Superoxides | 2003 |
Phytoalexin resveratrol attenuates the mutagenicity of the heterocyclic amines 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Topics: Animals; Antimutagenic Agents; Cell Line; Cricetinae; Imidazoles; Mutagens; Phytoalexins; Plant Extracts; Quinoxalines; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2004 |
Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Division; Cell Line; Cell Line, Tumor; Disease Models, Animal; Endothelium, Vascular; Flow Cytometry; Glioma; Kinetics; Neovascularization, Pathologic; Rats; Resveratrol; Stilbenes; Umbilical Veins | 2004 |
Modulation of androgen receptor-dependent transcription by resveratrol and genistein in prostate cancer cells.
Topics: Amino Acid Sequence; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genistein; Humans; Male; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-raf; Receptors, Androgen; Resveratrol; Signal Transduction; Stilbenes; Transfection | 2004 |
Resveratrol derivatives and their role as potassium channels modulators.
Topics: Animals; Mice; Molecular Structure; Potassium Channels, Voltage-Gated; Rats; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2004 |
Human hepatic cell uptake of resveratrol: involvement of both passive diffusion and carrier-mediated process.
Topics: Biological Availability; Biological Transport, Active; Carrier Proteins; Cell Line; Cell Line, Tumor; Diffusion; Hepatoblastoma; Hepatocytes; Humans; Metabolic Clearance Rate; Resveratrol; Stilbenes; Temperature; Tissue Distribution | 2004 |
Regioselective oxidative coupling of 4-hydroxystilbenes: synthesis of resveratrol and epsilon-viniferin (E)-dehydrodimers.
Topics: Benzofurans; Catalysis; Combinatorial Chemistry Techniques; Indicators and Reagents; Molecular Structure; Oxidation-Reduction; Resveratrol; Stereoisomerism; Stilbenes | 2004 |
Potent induction of cellular antioxidants and phase 2 enzymes by resveratrol in cardiomyocytes: protection against oxidative and electrophilic injury.
Topics: Aldehydes; Animals; Antibiotics, Antineoplastic; Antioxidants; Catalase; Cell Survival; Cells, Cultured; Doxorubicin; Enzyme Induction; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Myocytes, Cardiac; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Xanthine Oxidase | 2004 |
Inhibitory effects of Polygonum cuspidatum water extract (PCWE) and its component resveratrol [correction of rasveratrol] on acyl-coenzyme A-cholesterol acyltransferase activity for cholesteryl ester synthesis in HepG2 cells.
Topics: Animals; Cell Division; Cell Line; Cholesterol Esters; Dose-Response Relationship, Drug; Fallopia japonica; Hepatocytes; Humans; Microsomes, Liver; Plant Extracts; Plant Roots; Rats; Resveratrol; Sterol O-Acyltransferase; Stilbenes; Water | 2004 |
Protective effect of resveratrol against 6-hydroxydopamine-induced impairment of renal p-aminohippurate transport.
Topics: Animals; Antioxidants; Biological Transport; Cephaloridine; Cisplatin; Culture Media; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Cortex; Male; Oxidopamine; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2004 |
Inhibitory effects of Scutellaria barbata D. Don on human uterine leiomyomal smooth muscle cell proliferation through cell cycle analysis.
Topics: Antineoplastic Agents; Berberine; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Flavonoids; Flow Cytometry; Humans; Leiomyoma; Myocytes, Smooth Muscle; Myometrium; Plant Extracts; Plant Stems; Resveratrol; Scutellaria; Stilbenes; Tumor Cells, Cultured; Uterine Neoplasms | 2004 |
Resveratrol inhibits the release of mediators from bone marrow-derived mouse mast cells in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Dose-Response Relationship, Drug; Female; Histamine; Leukotrienes; Mast Cells; Mice; Mice, Inbred BALB C; Phytotherapy; Plants, Medicinal; Prostaglandin D2; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2004 |
Resveratrol protects against 4-HNE induced oxidative stress and apoptosis in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Aldehydes; Angiogenesis Inhibitors; Animals; Apoptosis; Cell Death; Dose-Response Relationship, Drug; Mice; Oxidative Stress; Resveratrol; Stilbenes | 2004 |
DNA damage in healthy term neonate.
Topics: Antioxidants; Colostrum; Coumarins; DNA Damage; Fetal Blood; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Hymecromone; Infant, Newborn; Leukocytes, Mononuclear; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Phenols; Polyphenols; Quercetin; Resveratrol; Rutin; Stilbenes | 2004 |
Estrogenic effects of resveratrol in breast cancer cells expressing mutant and wild-type estrogen receptors: role of AF-1 and AF-2.
Topics: Breast Neoplasms; Cell Line, Tumor; Estrogens; Humans; Resveratrol; RNA, Messenger; Stilbenes; Transforming Growth Factor alpha | 2004 |
Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin.
Topics: Administration, Topical; Animals; Blotting, Western; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Down-Regulation; Female; Immunohistochemistry; Leukocytes; Mice; Mice, Hairless; Mitogen-Activated Protein Kinase Kinases; Molecular Structure; Proliferating Cell Nuclear Antigen; Radiation Injuries, Experimental; Resveratrol; Skin; Stilbenes; Time Factors; Tumor Suppressor Protein p53; Ultraviolet Rays; Up-Regulation | 2004 |
Antioxidants in Sicilian wines: analytic and compositive aspects.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Glucosides; Microscopy, Electron; Resveratrol; Sicily; Stilbenes; Wine | 2003 |
Evidence for resveratrol-induced preservation of brain mitochondria functions after hypoxia-reoxygenation.
Topics: Animals; Antioxidants; Apoptosis; Cell Hypoxia; Cytochromes c; Dose-Response Relationship, Drug; In Vitro Techniques; Lipid Peroxidation; Membrane Fluidity; Mitochondria; Oxygen; Prosencephalon; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2003 |
Effect of resveratrol and catechin on PC12 tyrosine kinase activities and their synergistic protection from beta-amyloid toxicity.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Cell Proliferation; Drug Synergism; Flow Cytometry; PC12 Cells; Peptide Fragments; Protein-Tyrosine Kinases; Rats; Resveratrol; Stilbenes | 2003 |
Wine and tumors: study of resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes; Wine | 2003 |
Resveratrol structure and ceramide-associated growth inhibition in prostate cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Ceramides; Humans; Male; Prostatic Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors | 2003 |
Differential regulation of resveratrol on lipopolysacchride-stimulated human macrophages with or without IFN-gamma pre-priming.
Topics: Antigen-Presenting Cells; Antigens, CD; B7-2 Antigen; Cell Death; Cell Differentiation; Cell Survival; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-12; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Phenotype; Recombinant Proteins; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Thymidine; Tumor Necrosis Factor-alpha | 2004 |
Enhanced radiation-induced apoptosis of cancer cell lines after treatment with resveratrol.
Topics: Apoptosis; Cell Division; Cell Survival; Dose-Response Relationship, Radiation; Female; HeLa Cells; Humans; Radiation Tolerance; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2004 |
Resveratrol inhibits TCDD-induced expression of CYP1A1 and CYP1B1 and catechol estrogen-mediated oxidative DNA damage in cultured human mammary epithelial cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Breast; Cell Division; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA; DNA Damage; Electrophoretic Mobility Shift Assay; Epithelial Cells; Estradiol; Estrogens, Catechol; Female; Humans; Oxidative Stress; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2004 |
Effects of resveratrol on the expression of a panel of genes interacting with the BRCA1 oncosuppressor in human breast cell lines.
Topics: Antineoplastic Agents, Phytogenic; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Fibrocystic Breast Disease; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Receptors, Estrogen; Resveratrol; Stilbenes; Transcription, Genetic; Tumor Suppressor Proteins | 2004 |
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
Topics: Base Sequence; Cell Line, Tumor; Cell Survival; DNA Primers; Histone Deacetylases; Humans; NF-kappa B; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic | 2004 |
Polyphenol glucosylating activity in cell suspensions of grape (Vitis vinifera).
Topics: Cells, Cultured; Flavonoids; Fruit; Glucosyltransferases; Glycosylation; Phenols; Polyphenols; Resveratrol; Stilbenes; Vitis | 2004 |
Resveratrol inhibits benzo[a]pyrene-DNA adduct formation in human bronchial epithelial cells.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Bronchi; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; Epithelial Cells; Gene Expression; Humans; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2004 |
Identification of a p53-dependent pathway in the induction of apoptosis of human breast cancer cells by the natural product, resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Astrocytoma; Blotting, Western; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Transcriptional Activation; Tumor Suppressor Protein p53 | 2004 |
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Biological Transport; Caloric Restriction; Cell Line; DNA-Binding Proteins; Gene Deletion; Gene Expression; Humans; Lipid Metabolism; Lipolysis; Longevity; Mice; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Co-Repressor 2; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Resveratrol; RNA Interference; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factors; Triglycerides | 2004 |
In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Keratinocytes; Melanoma; Necrosis; Poly(ADP-ribose) Polymerases; Resveratrol; S Phase; Stilbenes; Temozolomide; Time Factors | 2004 |
Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cell Line; Dexamethasone; Granulocyte-Macrophage Colony-Stimulating Factor; Inflammation; Kinetics; Lung; Quercetin; Respiratory Mucosa; Resveratrol; Stilbenes; Transfection | 2004 |
[Effect of resveratrol alone and its combination with cyclosporin A on the immune function of human peripheral blood T lymphocytes].
Topics: Cyclosporine; Drug Synergism; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Resveratrol; Stilbenes; T-Lymphocytes | 2003 |
Differential regulation of CYP1A1 and CYP1B1 expression in resveratrol-treated human medulloblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Flow Cytometry; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Medulloblastoma; Membrane Glycoproteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors | 2004 |
Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Estradiol; Female; Humans; Phosphorylation; Protein Processing, Post-Translational; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2004 |
Alteration in phase I and II enzyme activities and polycyclic aromatic hydrocarbons-DNA adduct formation by plant phenolics in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Benzo(a)pyrene; DNA Adducts; Dose-Response Relationship, Drug; Epidermis; Female; Hydroxybenzoates; Mice; Polycyclic Aromatic Hydrocarbons; Resveratrol; Stilbenes | 2004 |
In vitro effects of the polyphenols resveratrol, mangiferin and (-)-epigallocatechin-3-gallate on the scuticociliate fish pathogen Philasterides dicentrarchi.
Topics: Analysis of Variance; Animals; Antiprotozoal Agents; Catechin; Dose-Response Relationship, Drug; Fish Diseases; Flatfishes; In Vitro Techniques; Oligohymenophorea; Protozoan Infections, Animal; Resveratrol; Stilbenes; Xanthones | 2004 |
The protective effects of resveratrol against changes in blood platelet thiols induced by platinum compounds.
Topics: Antioxidants; Blood Platelets; Cisplatin; Cysteine; Dipeptides; Glutathione; Humans; In Vitro Techniques; Oxidative Stress; Resveratrol; Stilbenes; Sulfhydryl Compounds | 2004 |
In vitro effects of resveratrol on the viability and infectivity of the microsporidian Encephalitozoon cuniculi.
Topics: Animals; Cell Line; Culture Media; Encephalitozoon cuniculi; Haplorhini; Resveratrol; Spores, Protozoan; Stilbenes; Vasodilator Agents | 2004 |
Three new resveratrol oligomers from the stem bark of Vatica pauciflora.
Topics: Ericales; Indonesia; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Resveratrol; Stereoisomerism; Stilbenes | 2004 |
New stilbene derivatives from Calligonum leucocladum.
Topics: Drug Resistance, Multiple; Glucosides; Methicillin Resistance; Molecular Structure; Oxacillin; Plants, Medicinal; Polygonaceae; Resveratrol; Staphylococcus aureus; Stilbenes; Uzbekistan | 2004 |
Resveratrol induces FasL-related apoptosis through Cdc42 activation of ASK1/JNK-dependent signaling pathway in human leukemia HL-60 cells.
Topics: Angiogenesis Inhibitors; Apoptosis; Blotting, Western; cdc42 GTP-Binding Protein; Enzyme Activation; Fas Ligand Protein; Flow Cytometry; Fluorescent Antibody Technique; HL-60 Cells; Humans; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Membrane Glycoproteins; Resveratrol; Signal Transduction; Stilbenes; Transfection | 2005 |
Resveratrol, a red wine polyphenol, protects spinal cord from ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Flavonoids; Free Radical Scavengers; Male; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Paraplegia; Phenols; Polyphenols; Rabbits; Reperfusion Injury; Resveratrol; Spinal Cord; Spinal Cord Ischemia; Stilbenes; Wine | 2004 |
The effects of antioxidants on peroxynitrite-induced changes in platelet proteins.
Topics: Antioxidants; Blood Platelets; Blood Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Nitrates; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Resveratrol; Stilbenes; Tyrosine | 2004 |
Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB.
Topics: Alleles; Antioxidants; Biological Transport; Dose-Response Relationship, Drug; HeLa Cells; Humans; NF-kappa B; Oxidative Stress; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proto-Oncogene Proteins c-abl; Resveratrol; Serine; src-Family Kinases; Stilbenes | 2004 |
Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; Enzyme Induction; Liver; Lung; Male; Mice; Mice, Inbred BALB C; Microsomes; Ornithine Decarboxylase; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes | 2004 |
Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Mice; Neuroblastoma; Resveratrol; Stilbenes | 2004 |
Benzothiadiazole enhances resveratrol and anthocyanin biosynthesis in grapevine, meanwhile improving resistance to Botrytis cinerea.
Topics: Anthocyanins; Botrytis; Plant Diseases; Resveratrol; Stilbenes; Thiadiazoles; Vitis | 2004 |
Inhibition of inducible nitric oxide synthase expression by yuccaol C from Yucca schidigera roezl.
Topics: Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Electrophoretic Mobility Shift Assay; Enzyme Repression; Escherichia coli; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Phenols; Plant Extracts; Resveratrol; Spiro Compounds; Stilbenes; Yucca | 2004 |
Resveratrol to the rescue.
Topics: Animals; Drosophila; Longevity; Nematoda; Resveratrol; Sirtuins; Stilbenes | 2004 |
Sirtuin activators mimic caloric restriction and delay ageing in metazoans.
Topics: Aging; Alleles; Animal Feed; Animals; Caenorhabditis elegans; Caloric Restriction; Drosophila melanogaster; Feeding Behavior; Female; Fertility; Flavonoids; Flavonols; Genotype; Longevity; Male; Mutation; Phenols; Polyphenols; Resveratrol; Sirtuins; Stilbenes; Survival Rate; Time Factors | 2004 |
Resveratrol, pterostilbene, and piceatannol in vaccinium berries.
Topics: Antioxidants; Fruit; Phenols; Resveratrol; Species Specificity; Stilbenes; Vaccinium | 2004 |
Hypoxia-inducible factor 1alpha- mediated resistance to phenolic anticancer.
Topics: Animals; Antineoplastic Agents; Antioxidants; Blotting, Western; Capsaicin; Catechin; Cell Line, Tumor; Cell Survival; DNA-Binding Proteins; Drug Resistance, Neoplasm; Hypoxia-Inducible Factor 1; Nuclear Proteins; Resveratrol; Stilbenes; Time Factors; Transcription Factors; Transfection | 2004 |
Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Humans; Inhibitor of Apoptosis Proteins; Jurkat Cells; Microtubule-Associated Proteins; Neoplasm Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Survivin | 2004 |
Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes.
Topics: Antioxidants; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Humans; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Recombinant Proteins; Resveratrol; Stilbenes | 2004 |
Effects of resveratrol on gene expression in renal cell carcinoma.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Renal Cell; Chemoprevention; Disease Progression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Phenols; Resveratrol; Ribonucleotide Reductases; Stilbenes; Vasodilator Agents | 2004 |
trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Eukaryotic Initiation Factor-4E; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Luciferases; MAP Kinase Signaling System; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphoproteins; Proteasome Endopeptidase Complex; Protein Biosynthesis; Resveratrol; Ribosomal Protein S6 Kinases; RNA, Messenger; Stilbenes; Time Factors; Transcription Factors; Transfection; Vascular Endothelial Growth Factor A | 2004 |
[Chemopreventive effect of resveratrol to cancer].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Croton Oil; Ear Diseases; Edema; Epithelial Cells; Female; Male; Mice; Mice, Inbred ICR; Micronucleus Tests; Mutagenicity Tests; Ornithine Decarboxylase; Papilloma; Resveratrol; Salmonella typhimurium; Skin Neoplasms; Stilbenes | 2004 |
3,4',5-Trihydroxy-trans-stilbene (resveratrol) inhibits human cytomegalovirus replication and virus-induced cellular signaling.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cytomegalovirus; DNA Replication; DNA, Viral; Electrophoretic Mobility Shift Assay; ErbB Receptors; Fibroblasts; Humans; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Binding; Resveratrol; Signal Transduction; Sp1 Transcription Factor; Stilbenes; Time Factors; Viral Plaque Assay; Viral Proteins; Virus Replication | 2004 |
Expression of the grapevine stilbene synthase gene VST1 in papaya provides increased resistance against diseases caused by Phytophthora palmivora.
Topics: Acyltransferases; Carica; Disease Susceptibility; Gene Expression Regulation, Plant; Phytophthora; Plant Diseases; Plants, Genetically Modified; Resveratrol; RNA, Messenger; RNA, Plant; Stilbenes; Up-Regulation; Vitis | 2004 |
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.
Topics: 3T3 Cells; Animals; Axons; Axotomy; Benzamides; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Ganglia, Spinal; Humans; Lentivirus; Mice; Mutation; NAD; Naphthols; Nerve Tissue Proteins; Neuroprotective Agents; Nicotinamide-Nucleotide Adenylyltransferase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes; Ubiquitin-Protein Ligases; Vincristine; Wallerian Degeneration | 2004 |
Effect of trans-resveratrol on the thrombogenicity and atherogenicity in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Carotid Artery Thrombosis; Cholesterol; Diet, Atherogenic; Dietary Fats; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Aggregation; Radiation Injuries, Experimental; Receptors, LDL; Resveratrol; Stilbenes; Thrombophilia; Triglycerides | 2004 |
Prevention and repair of DNA damage by selected phytochemicals as measured by single cell gel electrophoresis.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinogens; Cell Culture Techniques; Comet Assay; Cricetinae; Cricetulus; Curcumin; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Ellagic Acid; Fibroblasts; Indoles; Methylnitronitrosoguanidine; Resveratrol; Stilbenes | 2004 |
Determination of piceid and resveratrol in Spanish wines deriving from Monastrell (Vitis vinifera L.) grape variety.
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fruit; Glucosides; Magnetic Resonance Spectroscopy; Resveratrol; Spain; Stilbenes; Vitis; Wine | 2004 |
Analysis of resveratrol as a lung cancer chemopreventive agent in A/J mice exposed to benzo[a]pyrene.
Topics: Angiogenesis Inhibitors; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Chemoprevention; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Female; Gene Expression Regulation, Neoplastic; Lung Neoplasms; Mice; Phenols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2004 |
Phytochemical analysis and anti-allergic study of Agave intermixta Trel. and Cissus sicyoides L.
Topics: Agave; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cissus; Diosgenin; Histamine Release; Male; Mast Cells; Plant Extracts; Plant Leaves; Plant Stems; Rats; Rats, Wistar; Resveratrol; Sapogenins; Stilbenes | 2004 |
Overexpression of c-Jun induced by quercetin and resverol inhibits the expression and function of the androgen receptor in human prostate cancer cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Humans; Male; Phenols; Prostatic Neoplasms; Proto-Oncogene Proteins c-jun; Quercetin; Receptors, Androgen; Resveratrol; Stilbenes; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 2004 |
Mitochondrial phospholipid bilayer structure is ruined after liver oxidative injury in vivo.
Topics: Animals; Anisotropy; Carbon Tetrachloride; Electron Spin Resonance Spectroscopy; Lipid Bilayers; Liver; Membrane Fluidity; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Phospholipids; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2004 |
Resveratrol-associated renal toxicity.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Dose-Response Relationship, Drug; Female; Intubation, Gastrointestinal; Kidney; Kidney Diseases; Leukocyte Count; Male; No-Observed-Adverse-Effect Level; Organ Size; Rats; Resveratrol; Sex Characteristics; Stilbenes | 2004 |
Fast determination of the total free resveratrol content in wine by direct-exposure-probe, positive-ion chemical ionization and collision-induced-dissociation mass spectrometry.
Topics: Antioxidants; Reproducibility of Results; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Time Factors; Wine | 2004 |
High absorption but very low bioavailability of oral resveratrol in humans.
Topics: Administration, Oral; Adult; Antineoplastic Agents, Phytogenic; Biological Availability; Biotransformation; Chromatography, High Pressure Liquid; Feces; Female; Half-Life; Humans; Injections, Intravenous; Intestinal Absorption; Male; Mass Spectrometry; Resveratrol; Stilbenes; Sulfates | 2004 |
Inhibition of osteogenesis in vitro by a cigarette smoke-associated hydrocarbon combined with Porphyromonas gingivalis lipopolysaccharide: reversal by resveratrol.
Topics: Alveolar Bone Loss; Animals; Benzo(a)pyrene; Cells, Cultured; Drug Synergism; In Vitro Techniques; Lipopolysaccharides; Male; Nicotiana; Osteogenesis; Porphyromonas gingivalis; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Smoke; Stilbenes | 2004 |
Inhibition of thrombin-induced signaling by resveratrol and quercetin: effects on adenosine nucleotide metabolism in endothelial cells and platelet-neutrophil interactions.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Antioxidants; Blood Platelets; Cell Communication; Cells, Cultured; Chemotaxis; Coculture Techniques; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Neutrophils; Platelet Aggregation Inhibitors; Quercetin; Resveratrol; Signal Transduction; Stilbenes; Thrombin | 2004 |
Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress.
Topics: Animals; Antioxidants; Astrocytes; Caffeic Acids; Cell Survival; Enzyme Induction; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Resveratrol; RNA, Messenger; Stilbenes | 2004 |
Pharmacological preconditioning with resveratrol: role of CREB-dependent Bcl-2 signaling via adenosine A3 receptor activation.
Topics: Adenosine A3 Receptor Antagonists; Animals; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Heart; Male; Myocardial Infarction; Myocytes, Cardiac; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A3; Resveratrol; Signal Transduction; Stilbenes; Theophylline | 2005 |
Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity.
Topics: Administration, Oral; Anti-HIV Agents; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Didanosine; Dose-Response Relationship, Drug; Drug Synergism; Glucuronides; HIV Infections; Humans; Hydrolysis; Leukocytes, Mononuclear; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors | 2004 |
Crystal structure of quinone reductase 2 in complex with resveratrol.
Topics: Binding, Competitive; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Humans; K562 Cells; Protein Binding; Quinone Reductases; Resveratrol; RNA Interference; Stilbenes; Transfection; Vitamin K 3 | 2004 |
Inhibition of COX isoforms by nutraceuticals.
Topics: Biflavonoids; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Isoenzymes; Isoflavones; Membrane Proteins; Neoplasms; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Resveratrol; Ruscus; Stilbenes | 2004 |
EPR evaluation of the antiradical activity of wines containing high concentrations of resveratrol.
Topics: Drug Evaluation, Preclinical; Drug Synergism; Electron Spin Resonance Spectroscopy; Flavonoids; Free Radical Scavengers; Free Radicals; Italy; Phenols; Polyphenols; Resveratrol; Stilbenes; Vitis; Wine | 2004 |
Influence of lipophilicity on the interactions of hydroxy stilbenes with cytochrome P450 3A4.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Hydroxyl Radical; Kinetics; Oxidation-Reduction; Protein Binding; Resveratrol; Solvents; Stilbenes; Substrate Specificity; Testosterone | 2004 |
trans-Resveratrol, quercetin, (+)-catechin, and (-)-epicatechin content in south Italian monovarietal wines: relationship with maceration time and marc pressing during winemaking.
Topics: Catechin; Food Handling; Fruit; Italy; Quercetin; Resveratrol; Stilbenes; Time Factors; Vitis; Wine | 2004 |
Effect of resveratrol and in combination with 5-FU on murine liver cancer.
Topics: Animals; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Cell Cycle Proteins; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Liver Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Resveratrol; Stilbenes; Survival Rate | 2004 |
A fine balancing act of type III polyketide synthase.
Topics: Acyltransferases; Chalcones; Resveratrol; Stilbenes | 2004 |
An aldol switch discovered in stilbene synthases mediates cyclization specificity of type III polyketide synthases.
Topics: Acyltransferases; Amino Acid Sequence; Crystallography, X-Ray; Cyclization; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Resveratrol; Stilbenes; Substrate Specificity | 2004 |
Identification and purification of resveratrol targeting proteins using immobilized resveratrol affinity chromatography.
Topics: Adsorption; Biomarkers, Tumor; Cell Line, Tumor; Chromatography, Affinity; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Male; Neoplasm Proteins; Prostatic Neoplasms; Protein Binding; Protein Interaction Mapping; Resveratrol; Stilbenes | 2004 |
Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA Damage; Enzyme Induction; Estrogen Receptor beta; Estrogens; Genistein; Humans; Ligands; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Phytoestrogens; Response Elements; Resveratrol; Stilbenes; Transcription, Genetic | 2005 |
Induction of the paraoxonase-1 gene expression by resveratrol.
Topics: Aryldialkylphosphatase; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Chromosome Mapping; Enzyme Induction; Estrogen Receptor alpha; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Liver Neoplasms; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Response Elements; Resveratrol; Stilbenes; Transcriptional Activation; Transfection; Xenobiotics | 2004 |
G2/M cell cycle arrest and induction of apoptosis by a stilbenoid, 3,4,5-trimethoxy-4'-bromo-cis-stilbene, in human lung cancer cells.
Topics: Analysis of Variance; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; DNA Fragmentation; Flow Cytometry; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2004 |
Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Membrane Proteins; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Protein Structure, Secondary; Resveratrol; Sheep; Stilbenes; Structure-Activity Relationship | 2004 |
Resveratrol: a whiff that induces a biologically specific tsunami.
Topics: Angiogenesis Inhibitors; Antioxidants; Chemoprevention; Clinical Trials as Topic; Humans; Neoplasms; Phenols; Resveratrol; Ribonucleotide Reductases; Stilbenes; Vasodilator Agents | 2004 |
The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.
Topics: Amyloid; Antioxidants; Binding Sites; Binding, Competitive; Carrier Proteins; Crystallography, X-Ray; Diethylstilbestrol; Dose-Response Relationship, Drug; Drug Design; Electrons; Escherichia coli; Humans; Hydrogen Bonding; Kinetics; Ligands; Models, Chemical; Models, Molecular; Prealbumin; Protein Binding; Protein Conformation; Resveratrol; Stilbenes; Thyroxine | 2004 |
Differential sensitivity to resveratrol-induced apoptosis of human chronic myeloid (K562) and acute lymphoblastic (HSB-2) leukemia cells.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Proliferation; Cell Survival; Cytochromes c; Enzyme Activation; Glutathione; Humans; K562 Cells; Leukemia; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2004 |
Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.
Topics: Animals; Blood Proteins; Cachexia; Cells, Cultured; Chymotrypsin; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; I-kappa B Proteins; Male; Mice; Mice, Inbred Strains; Muscle Fibers, Skeletal; Muscle, Skeletal; Neoplasms, Experimental; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Proteoglycans; Resveratrol; Stilbenes; Ubiquitins; Weight Loss | 2004 |
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinoma; Caspases; Cell Line, Tumor; Colonic Neoplasms; fas Receptor; Flow Cytometry; Humans; Ligands; Lipid Metabolism; Lipids; Membrane Glycoproteins; Membrane Microdomains; Mitochondria; Nystatin; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Resveratrol; Signal Transduction; Stilbenes; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Necrosis Factor-alpha | 2004 |
A novel assay for replicative lifespan in Saccharomyces cerevisiae.
Topics: Colony Count, Microbial; Culture Media; Galactose; Glucose; Histone Deacetylases; Mutagenesis, Insertional; Oxidants; Oxidative Stress; Oxygen Consumption; Paraquat; Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Stilbenes | 2004 |
Phytoestrogens in common herbs regulate prostate cancer cell growth in vitro.
Topics: Antineoplastic Agents, Hormonal; Catechin; Cell Cycle; Cell Division; Curcumin; DNA Fragmentation; Humans; Male; Phytoestrogens; Prostatic Neoplasms; Quercetin; Receptors, Estrogen; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2004 |
Resveratrol and propolis as necrosis or apoptosis inducers in human prostate carcinoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Male; Necrosis; Propolis; Prostatic Neoplasms; Reactive Oxygen Species; Resveratrol; Stilbenes | 2004 |
Alterations in activating protein 1 composition correlate with phenotypic differentiation changes induced by resveratrol in human melanoma.
Topics: Antioxidants; Apoptosis; Cell Cycle; Cell Line; Cell Line, Tumor; Humans; Infant, Newborn; Melanocytes; Melanoma; Phenotype; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2005 |
Resveratrol may be a powerful cancer-fighting ally.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Line, Tumor; Histone Deacetylases; Humans; Neoplasms; NF-kappa B p50 Subunit; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factors; Tumor Necrosis Factor-alpha | 2004 |
Inhibition of cardiac fibroblast proliferation and myofibroblast differentiation by resveratrol.
Topics: Angiotensin II; Animals; Antioxidants; Cell Differentiation; Cell Division; Cells, Cultured; Drug Interactions; Epidermal Growth Factor; Fibroblasts; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Vasoconstrictor Agents | 2005 |
[Effects of meteorological factors and mineral elements on the content of resveratrol in Polygonum cuspidatum rootstalk].
Topics: Calcium; Copper; Fallopia japonica; Iron; Meteorological Concepts; Minerals; Plant Roots; Regression Analysis; Resveratrol; Stilbenes | 2004 |
Differential antioxidant properties of red wine in water soluble and lipid soluble peroxyl radical generating systems.
Topics: Amidines; Animals; Antioxidants; Azo Compounds; Catechin; In Vitro Techniques; Lipids; Lipoproteins, LDL; Nitriles; Oxidants; Oxidation-Reduction; Peroxides; Quercetin; Rabbits; Resveratrol; Rutin; Solubility; Stilbenes; Vitamin E; Water; Wine | 2004 |
Liquid chromatography-electrospray tandem mass spectrometry of cis-resveratrol and trans-resveratrol: development, validation, and application of the method to red wine, grape, and winemaking byproducts.
Topics: Chromatography, Liquid; Food Handling; Fruit; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Vitis; Wine | 2004 |
Inhibition sites in F1-ATPase from bovine heart mitochondria.
Topics: Animals; ATPase Inhibitory Protein; Aurovertins; Bacillus; Binding Sites; Binding, Competitive; Cattle; Inhibitory Concentration 50; Melitten; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Models, Molecular; Molecular Structure; Peptides; Proteins; Resveratrol; Rhodamines; Stilbenes | 2005 |
Inhibitory effect of epidermal growth factor on resveratrol-induced apoptosis in prostate cancer cells is mediated by protein kinase C-alpha.
Topics: Apoptosis; Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2004 |
Effects of uvalino, a new autochthonous wine, on the inhibition of the production of hydroxyl radicals.
Topics: Antioxidants; Cyclic N-Oxides; Drug Evaluation, Preclinical; Electron Spin Resonance Spectroscopy; Hydrogen Peroxide; Hydroxyl Radical; Iron; Medicine, Traditional; Resveratrol; Spin Trapping; Stilbenes; Wine | 2004 |
Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia.
Topics: Analysis of Variance; Animals; Coronary Circulation; Disease Models, Animal; Hemodynamics; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Sensitivity and Specificity; Stilbenes; Survival Rate | 2004 |
Structural basis for antioxidant activity of trans-resveratrol: ab initio calculations and crystal and molecular structure.
Topics: Antioxidants; Crystallization; Hydrogen Bonding; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2004 |
Mechanism-based inactivation of COX-1 by red wine m-hydroquinones: a structure-activity relationship study.
Topics: Cardiotonic Agents; Catechin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hydroquinones; Isoenzymes; Molecular Structure; Peroxidase; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Resveratrol; Stilbenes; Structure-Activity Relationship; Wine | 2004 |
Resveratrol-induced cell growth inhibition and apoptosis is associated with modulation of phosphoglycerate mutase B in human prostate cancer cells: two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and mass spectrometry evaluation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Electrophoresis, Polyacrylamide Gel; Humans; Male; Mass Spectrometry; Phosphoglycerate Mutase; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2004 |
The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry.
Topics: Caffeic Acids; Candida albicans; Chromatography, High Pressure Liquid; Ergosterol; Fluconazole; Lanosterol; Naphthalenes; Phenols; Resveratrol; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Squalene; Stilbenes | 2005 |
Resveratrol inhibits cell cycle progression in U937 cells.
Topics: Anticarcinogenic Agents; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Growth Inhibitors; Humans; Neoplasms; Resveratrol; Stilbenes; U937 Cells | 2005 |
Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells.
Topics: Aorta; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Muscle, Smooth, Vascular; Resveratrol; Stilbenes | 2005 |
Resveratrol inhibits nitric oxide and TNF-alpha production by lipopolysaccharide-activated microglia.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; I-kappa B Proteins; Lipopolysaccharides; Mice; Microglia; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2005 |
Drinking red wine may prevent cancer.
Topics: Anticarcinogenic Agents; Antioxidants; Humans; Neoplasms; Resveratrol; Stilbenes; Wine | 2004 |
Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Blood Pressure; Blotting, Western; Cardiomegaly; Dose-Response Relationship, Drug; Echocardiography; Enzyme Activation; Free Radicals; Glutathione Peroxidase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Heart Ventricles; Hydrogen Peroxide; L-Lactate Dehydrogenase; Leucine; Lipid Peroxidation; Malondialdehyde; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Chemical; Myocytes, Cardiac; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Superoxide Dismutase; Time Factors; Transcription Factor AP-1 | 2005 |
Electrophysiological effects of resveratrol on guinea pig papillary muscles.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Papillary Muscles; Resveratrol; Stilbenes | 2004 |
Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Blotting, Western; Cattle; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Flavonoids; Fulvestrant; Humans; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Microcirculation; Models, Biological; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenols; Phosphorylation; Polyphenols; Resveratrol; Serine; Signal Transduction; Stilbenes; Tamoxifen; Time Factors; Transfection; Umbilical Veins; Wine | 2005 |
Potential utility of natural polyphenols for reversing fat-induced insulin resistance.
Topics: Adipocytes; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Flavonoids; Humans; I-kappa B Kinase; Insulin Resistance; Models, Biological; Phenols; Polyphenols; Probenecid; Protein Serine-Threonine Kinases; Resveratrol; Silybin; Silymarin; Stilbenes | 2005 |
Anti-angiogenic activity of resveratrol, a natural compound from medicinal plants.
Topics: Angiogenesis Inhibitors; Animals; Cell Adhesion; Cell Division; Cell Movement; Endothelial Cells; Humans; Male; Matrix Metalloproteinase Inhibitors; Plants, Medicinal; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2005 |
FADD-dependent apoptosis induction in Jurkat leukemia T-cells by the resveratrol analogue, 3,4,5-trihydroxy-trans-stilbene.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Fas-Associated Death Domain Protein; Humans; Jurkat Cells; Resveratrol; Stilbenes | 2005 |
Resveratrol inhibits phorbol ester-induced cyclooxygenase-2 expression in mouse skin: MAPKs and AP-1 as potential molecular targets.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cyclooxygenase 2; Female; Gene Expression Regulation, Enzymologic; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Resveratrol; Skin; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2004 |
Antinociceptive effect of trans-resveratrol in rats: Involvement of an opioidergic mechanism.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; India; Injections, Intraperitoneal; Male; Morphine; Naloxone; Pain Measurement; Phytoalexins; Plant Extracts; Rats; Rats, Wistar; Receptors, Opioid; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Time Factors | 2004 |
Anticancer activity of resveratrol on implanted human primary gastric carcinoma cells in nude mice.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Division; DNA Primers; Humans; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Stomach Neoplasms; Transplantation, Heterologous | 2005 |
Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators.
Topics: Animals; Biochemistry; Cell Line; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Humans; Polychlorinated Dibenzodioxins; Rabbits; Receptors, Aryl Hydrocarbon; Receptors, Estradiol; Resveratrol; Stilbenes; Toxicity Tests; Transcriptional Activation | 2005 |
Effect of resveratrol on microcirculation disorder and lung injury following severe acute pancreatitis in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Lung; Male; Microcirculation; Pancreatitis; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Resveratrol reduces oxidative stress induced by platinum compounds in blood platelets.
Topics: Animals; Blood Platelets; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Oxidative Stress; Oxygen; Platinum Compounds; Resveratrol; Stilbenes; Swine | 2004 |
Effect of resveratrol on activation of nuclear factor kappa-B and inflammatory factors in rat model of acute pancreatitis.
Topics: Acute Disease; Animals; Antioxidants; Cholagogues and Choleretics; Disease Models, Animal; Interleukin-8; Male; NF-kappa B; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Resveratrol; Severity of Illness Index; Stilbenes; Taurocholic Acid; Tumor Necrosis Factor-alpha | 2005 |
Resveratrol protects against peroxynitrite-induced thiol oxidation in blood platelets.
Topics: Antioxidants; Blood Platelets; Cysteine; Dipeptides; Glutathione; Humans; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Resveratrol; Stilbenes; Sulfhydryl Compounds | 2004 |
Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma.
Topics: Annexin A5; Apoptosis; Catechin; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Curcuma; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Eosinophils; Flow Cytometry; Humans; Leukemia; Necrosis; Plant Extracts; Radiation Tolerance; Radiation, Ionizing; Resveratrol; Signal Transduction; Stilbenes; Time Factors; X-Rays | 2005 |
Effects of dietary chemopreventive phytochemicals on P-glycoprotein function.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Capsaicin; Catechols; Chemoprevention; Curcumin; Diet; Dose-Response Relationship, Drug; Fatty Alcohols; Humans; KB Cells; Plant Extracts; Resveratrol; Rhodamine 123; Stilbenes; Vinblastine | 2005 |
Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling.
Topics: Animals; Cells, Cultured; Cytokines; DNA; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; NF-kappa B; Oligonucleotide Array Sequence Analysis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stereoisomerism; Stilbenes | 2005 |
Scientists discover new approaches to manipulating AIDS virus.
Topics: Anti-HIV Agents; Genes, Viral; HIV; Humans; Resveratrol; Stilbenes; Virus Replication | 2004 |
Germination of peanut kernels to enhance resveratrol biosynthesis and prepare sprouts as a functional vegetable.
Topics: Antioxidants; Arachis; Diet; Germination; Resveratrol; Seedlings; Seeds; Stilbenes; Time Factors; Vegetables | 2005 |
Inhibiting effects of resveratrol and its glucoside piceid against Venturia inaequalis, the causal agent of apple scab.
Topics: Ascomycota; Chemical Phenomena; Chemistry, Physical; Fungicides, Industrial; Germination; Glucosides; Malus; Plant Diseases; Resveratrol; Solubility; Stilbenes | 2005 |
Hop as an interesting source of resveratrol for brewers: optimization of the extraction and quantitative study by liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humulus; Mass Spectrometry; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2005 |
Cardiology patient pages. Red wine and your heart.
Topics: Alcohol Drinking; Animals; Antioxidants; Arteriosclerosis; Cohort Studies; Cricetinae; Dose-Response Relationship, Drug; Female; Fibrinolytic Agents; Flavonoids; Follow-Up Studies; Gene Expression Regulation; Humans; Male; Middle Aged; Myocardial Infarction; Phenols; Phytotherapy; Polyphenols; Rabbits; Resveratrol; Risk; Stilbenes; Stroke; Wine | 2005 |
Resveratrol protects against neurotoxicity induced by kainic acid.
Topics: Animals; Biological Availability; Cell Death; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Male; Neuroglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2004 |
Effect of resveratrol and beta-sitosterol in combination on reactive oxygen species and prostaglandin release by PC-3 cells.
Topics: 6-Ketoprostaglandin F1 alpha; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Drug Synergism; Humans; Male; Phospholipases A; Prostaglandins; Reactive Oxygen Species; Resveratrol; Sitosterols; Stilbenes | 2005 |
Regulation of the human vitamin D3 receptor promoter in breast cancer cells is mediated through Sp1 sites.
Topics: Binding Sites; Breast Neoplasms; Consensus Sequence; CpG Islands; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Exons; Humans; Mutation; Promoter Regions, Genetic; Receptors, Calcitriol; Resveratrol; Sp1 Transcription Factor; Stilbenes; Transcriptional Activation; Tumor Cells, Cultured; Vitamin D | 2005 |
Chemo-enzymatic synthesis and cell-growth inhibition activity of resveratrol analogues.
Topics: Anticarcinogenic Agents; Candida; Catalysis; Cell Division; Fibroblasts; Humans; Hydrogenation; Lipase; Male; Methylation; Molecular Structure; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2005 |
A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts.
Topics: Apoptosis; Cell Division; Cell Line, Transformed; Fibroblasts; Humans; Mitochondria; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2005 |
Resveratrol interference with the cell cycle protects human neuroblastoma SH-SY5Y cell from paclitaxel-induced apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclin B; Cyclin B1; Cyclins; Flow Cytometry; G2 Phase; Humans; Immunoblotting; Maturation-Promoting Factor; Mitosis; Neuroblastoma; Paclitaxel; Resveratrol; Stilbenes | 2005 |
Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53-independent manner.
Topics: Activating Transcription Factor 3; Antineoplastic Agents; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; HCT116 Cells; Humans; Indoles; Resveratrol; Stilbenes; Trans-Activators; Tumor Suppressor Protein p53 | 2005 |
Ellagic acid and quercetin interact synergistically with resveratrol in the induction of apoptosis and cause transient cell cycle arrest in human leukemia cells.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Drug Synergism; Ellagic Acid; Humans; Leukemia; Quercetin; Resveratrol; Stilbenes | 2005 |
Resveratrol inhibits hepatoma cell invasion by suppressing gene expression of hepatocyte growth factor via its reactive oxygen species-scavenging property.
Topics: Animals; Carcinoma, Hepatocellular; Free Radical Scavengers; Gene Expression; Hepatocyte Growth Factor; Hypoxanthine; Liver Neoplasms; Male; Neoplasm Invasiveness; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Cells, Cultured; Xanthine Oxidase | 2004 |
Viniferin formation by COX-1: evidence for radical intermediates during co-oxidation of resveratrol.
Topics: Benzofurans; Catalysis; Chromatography, High Pressure Liquid; Cyclooxygenase 1; Mass Spectrometry; Models, Chemical; Molecular Structure; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Resorcinols; Resveratrol; Stilbenes; Structure-Activity Relationship | 2005 |
Inhibition of leukotriene biosynthesis by stilbenoids from Stemona species.
Topics: Alkaloids; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Leukotrienes; Molecular Structure; Plants, Medicinal; Resveratrol; Stemonaceae; Stilbenes; Thailand | 2005 |
Inhibition of 5-aminolevulinic acid-induced DNA damage by melatonin, N1-acetyl-N2-formyl-5-methoxykynuramine, quercetin or resveratrol.
Topics: Aminolevulinic Acid; Antioxidants; DNA; DNA Damage; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Kynuramine; Melatonin; Photosensitizing Agents; Porphyria, Acute Intermittent; Quercetin; Resveratrol; Stilbenes | 2005 |
Substrate-specific activation of sirtuins by resveratrol.
Topics: Antioxidants; Binding, Competitive; DNA, Ribosomal; Dose-Response Relationship, Drug; Fungal Proteins; Gene Silencing; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; In Vitro Techniques; Kinetics; Models, Chemical; Niacinamide; Peptides; Protein Binding; Recombination, Genetic; Resveratrol; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes; Substrate Specificity; Telomere; Time Factors; Transcription, Genetic; Tumor Suppressor Protein p53 | 2005 |
Resveratrol derivatives from Upuna borneensis.
Topics: Chromatography, Thin Layer; Ericales; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Resveratrol; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Stilbenes | 2005 |
Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells.
Topics: Biological Transport; Caco-2 Cells; Cell Membrane; Glucosides; Humans; Intestinal Mucosa; Kinetics; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Monosaccharide Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Resveratrol; Sodium-Glucose Transporter 1; Stilbenes | 2005 |
Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) on adenoma development in the Apc(Min+) mouse and cyclooxygenase-2 in human-derived colon cancer cells.
Topics: Adenoma; Animals; Antineoplastic Agents, Phytogenic; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 2; Diet; Dinoprostone; Female; Genes, APC; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tissue Distribution | 2005 |
Resveratrol-induced apoptosis in MCF-7 human breast cancer cells involves a caspase-independent mechanism with downregulation of Bcl-2 and NF-kappaB.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calpain; Caspase 3; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Nucleus; Chromones; Collagen; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Estrogens; Flow Cytometry; Humans; Immunoblotting; Immunoprecipitation; Matrix Metalloproteinase 9; Membrane Potentials; Mitochondria; Models, Biological; Morpholines; NF-kappa B; Nitrites; Oxygen; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Time Factors | 2005 |
Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Lung; Lymphocytes; Mammary Neoplasms, Animal; Mice; Mice, Transgenic; Neoplasm Metastasis; Receptor, ErbB-2; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Spleen; Stilbenes; Time Factors | 2005 |
Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition.
Topics: Antioxidants; Cell Death; Cell Line; Cell Proliferation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Hydrogen Peroxide; Mitogen-Activated Protein Kinase 1; Oxidative Stress; Pigment Epithelium of Eye; Resveratrol; Retinal Diseases; Signal Transduction; Stilbenes; Wine | 2005 |
Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4'-trimethoxystilbene.
Topics: Angiogenesis Inhibitors; Animals; Aorta; Cell Line, Transformed; Cell Proliferation; Chickens; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred BALB C; Microtubules; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Zebrafish | 2005 |
[Analysis for four isomers of resveratrol in red wine by high performance liquid chromatography].
Topics: beta-Glucosidase; Chromatography, High Pressure Liquid; Resveratrol; Stereoisomerism; Stilbenes; Wine | 2004 |
[Analysis of resveratrol by pressurized-capillary electrochromatography].
Topics: Capillary Electrochromatography; Chromatography, Liquid; Electrophoresis, Capillary; Molecular Structure; Pressure; Resveratrol; Stilbenes; Wine | 2004 |
Effect of resveratrol on high glucose-induced stress in human leukemia K562 cells.
Topics: Apoptosis; Base Sequence; DNA Primers; Enzyme Activation; Glucose; Humans; JNK Mitogen-Activated Protein Kinases; K562 Cells; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2005 |
Inhibition of blood platelet adhesion and secretion by different phenolics from Yucca schidigera Roezl. bark.
Topics: Animals; Blood Platelets; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Fibrinogen; Phenols; Plant Extracts; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Swine; Yucca | 2005 |
Resveratrol derivatives from the roots of Vitis thunbergii.
Topics: Antioxidants; Benzofurans; Biflavonoids; Catechin; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Roots; Plants, Medicinal; Platelet Aggregation Inhibitors; Proanthocyanidins; Resveratrol; Stilbenes; Taiwan; Vitis | 2005 |
Synergistic action of resveratrol, an ingredient of wine, with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Differentiation; Cytarabine; Deoxyribonucleotides; DNA; Drug Synergism; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Resveratrol; Ribavirin; Ribonucleotide Reductases; Stilbenes | 2005 |
Adsorption and desorption properties of trans-resveratrol on cellulose cotton.
Topics: Adsorption; Cellulose; Gossypium; Molecular Structure; Resveratrol; Solvents; Stilbenes; Temperature | 2005 |
Resveratrol, an extract of red wine, inhibits lipopolysaccharide induced airway neutrophilia and inflammatory mediators through an NF-kappaB-independent mechanism.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Budesonide; Cytokines; Dinoprostone; DNA; Gene Expression; Inflammation; Inflammation Mediators; Lipopolysaccharides; Lung; Male; Neutrophils; NF-kappa B; Nitric Oxide Synthase Type II; Peritoneum; Peroxidase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Wine | 2005 |
The cancer chemopreventive agent resveratrol induces tensin, a cell-matrix adhesion protein with signaling and antitumor activities.
Topics: Actins; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cycloheximide; Cytoplasm; Cytoskeleton; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; K562 Cells; Microfilament Proteins; Neoplasm Invasiveness; Neoplasms; Phosphatidylinositol 3-Kinases; Protein Synthesis Inhibitors; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Tensins; Time Factors | 2005 |
Resveratrol treatment controls microbial flora, prolongs shelf life, and preserves nutritional quality of fruit.
Topics: Food Preservation; Fruit; Fungi; Fungicides, Industrial; Nutritive Value; Resveratrol; Solanum lycopersicum; Stilbenes; Vitis | 2005 |
Toxicogenomics of resveratrol in rat liver.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Gene Expression Regulation; Genomics; Liver; Male; Oligonucleotide Array Sequence Analysis; Rats; Resveratrol; Sex Factors; Stilbenes | 2005 |
Antioxidant, prooxidant and cytotoxic activity of hydroxylated resveratrol analogues: structure-activity relationship.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Hydroxylation; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship | 2005 |
Mechanism of human SIRT1 activation by resveratrol.
Topics: Antioxidants; Binding Sites; Binding, Competitive; Cell Cycle; Chromatography, High Pressure Liquid; Coloring Agents; Coumarins; Crystallography, X-Ray; Gene Silencing; Histidine; Histone Deacetylases; Humans; Immunoprecipitation; Kinetics; Models, Chemical; Models, Molecular; Peptides; Protein Binding; Protein Conformation; Resveratrol; Rhodamines; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes; Substrate Specificity; Time Factors; Tumor Suppressor Protein p53 | 2005 |
Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling.
Topics: Adaptor Proteins, Signal Transducing; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Communication; Cell Cycle; Fas-Associated Death Domain Protein; Humans; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2005 |
Resveratrol-induced gene expression profiles in human prostate cancer cells.
Topics: Androgens; Antineoplastic Agents, Phytogenic; Cell Cycle; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Resveratrol; Stilbenes; Transcription, Genetic; Tumor Cells, Cultured; Wine | 2005 |
Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation.
Topics: Animals; Aortic Diseases; Arteriosclerosis; Catechin; Cricetinae; Disease Models, Animal; Hypercholesterolemia; Male; Mesocricetus; Quercetin; Resveratrol; Stilbenes; Wine | 2005 |
Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.
Topics: Amino Acid Sequence; Animals; Binding Sites; DNA Nucleotidyltransferases; DNA Replication; DNA-Directed DNA Polymerase; Humans; Kinetics; Mammals; Molecular Structure; Nucleic Acid Synthesis Inhibitors; Protein Binding; Resveratrol; Stilbenes; Structure-Activity Relationship; Substrate Specificity | 2005 |
Plant-derived anti-inflammatory compounds affect MIF tautomerase activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Caffeic Acids; Cattle; Curcumin; Enzyme Inhibitors; Humans; In Vitro Techniques; Intramolecular Oxidoreductases; Kidney; Macrophage Migration-Inhibitory Factors; Phenols; Phenylpyruvic Acids; Phloretin; Phytotherapy; Plants, Medicinal; Resveratrol; Stilbenes | 2005 |
Bioactivity and metabolism of trans-resveratrol orally administered to Wistar rats.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Diet; Erythrocytes; Feces; Glucuronides; Glutathione Transferase; Kidney; Liver; Magnetic Resonance Spectroscopy; Male; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfates | 2005 |
Effects of resveratrol, piceatannol, tri-acetoxystilbene, and genistein on the inflammatory response of human peripheral blood leukocytes.
Topics: Cell Survival; Cyclooxygenase 2; Dinoprostone; Gene Expression; Genistein; Humans; Inflammation; Interferon-gamma; Interleukin-1; Interleukin-6; Interleukin-8; Leukocytes; Leukocytes, Mononuclear; Lipopolysaccharides; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2005 |
Resveratrol and breast cancer risk.
Topics: Adult; Anticarcinogenic Agents; Breast Neoplasms; Case-Control Studies; Diet; Female; Fruit; Humans; Incidence; Middle Aged; Odds Ratio; Resveratrol; Risk Factors; Stilbenes; Switzerland; Wine | 2005 |
Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.
Topics: Breast Neoplasms; Cell Proliferation; Female; Humans; Iridaceae; Isoflavones; Molecular Structure; Phenols; Plants, Medicinal; Resveratrol; Rhizome; Stilbenes; Thailand; Tumor Cells, Cultured | 2005 |
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes.
Topics: Acetylation; Animals; Biological Transport; Cell Nucleus; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gluconeogenesis; Glucose; Green Fluorescent Proteins; Hepatocytes; Hydrogen Peroxide; Kinetics; Mice; Oxidative Stress; Phosphorylation; Photobleaching; Recombinant Fusion Proteins; Resveratrol; Sirtuins; Stilbenes; Transcription Factors; Transfection | 2005 |
Effects of different fractions of a red wine non-alcoholic extract on ischemia-reperfusion injury.
Topics: Animals; Argentina; Blood Pressure; Cardiotonic Agents; Flavonols; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Ventricular Function, Left; Wine | 2005 |
Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.
Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Antineoplastic Agents, Phytogenic; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Forkhead Transcription Factors; Homozygote; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Mutant Strains; Nerve Tissue Proteins; Neurons; Peptides; Resveratrol; Serotonin Plasma Membrane Transport Proteins; Sirtuins; Stilbenes; Transcription Factors | 2005 |
[Neuroprotection by resveratrol against cytotoxicity of oxidized low density lipoprotein in PC12 cells].
Topics: Animals; Cell Survival; Lipoproteins, LDL; Neuroprotective Agents; PC12 Cells; Rats; Resveratrol; Stilbenes | 2005 |
trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in healthy rats.
Topics: Animals; Antioxidants; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Seminiferous Tubules; Sperm Count; Spermatogenesis; Spermatozoa; Stilbenes; Testosterone; Vasodilator Agents; Vitis | 2005 |
Resveratrol and estradiol exert disparate effects on cell migration, cell surface actin structures, and focal adhesion assembly in MDA-MB-231 human breast cancer cells.
Topics: Actins; Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Membrane; Cell Movement; Cytoskeleton; Epidermal Growth Factor; ErbB Receptors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Humans; Protein-Tyrosine Kinases; Pseudopodia; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2005 |
Resveratrol, a polyphenolic phytoalexin protects against cyclosporine-induced nephrotoxicity through nitric oxide dependent mechanism.
Topics: Animals; Antioxidants; Blood Pressure; Blood Urea Nitrogen; Creatinine; Cyclosporine; Enzyme Inhibitors; Immunosuppressive Agents; Kidney; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Phytoalexins; Plant Extracts; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Weight Loss | 2005 |
[Study on thermostability and photo-isomerization of trans-resveratrol by high performance liquid chromatography and liquid chromatography-electrospray ionization-mass spectrometry].
Topics: Chromatography, High Pressure Liquid; Hot Temperature; Isomerism; Mass Spectrometry; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2004 |
Comparison of the phytoestrogen trans-resveratrol (3,4',5-trihydroxystilbene) structures from x-ray diffraction and solution NMR.
Topics: Binding Sites; Computer Simulation; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Phytoestrogens; Prealbumin; Protein Binding; Resveratrol; Stilbenes; X-Ray Diffraction | 2005 |
Interaction of resveratrol and genistein with nucleic acids.
Topics: Anticarcinogenic Agents; DNA; Genistein; Hydrogen Bonding; Resveratrol; RNA; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2005 |
Resveratrol-induced apoptotic death in human U251 glioma cells.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cytochromes c; Cytoplasm; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glioma; Humans; Kinetin; L-Lactate Dehydrogenase; Phenols; Poly(ADP-ribose) Polymerases; Polyphenols; Proto-Oncogene Proteins c-bcl-2; Purines; Resveratrol; Signal Transduction; Stilbenes; Subcellular Fractions; Time Factors; Up-Regulation | 2005 |
Effects of a phenolic compound, resveratrol, on the renal function and costimulatory adhesion molecule CD86 expression in rat kidneys with ischemia/reperfusion injury.
Topics: Animals; Antigens, CD; B7-2 Antigen; Creatinine; Endothelium, Vascular; Ischemia; Kidney; Kidney Cortex; Kidney Function Tests; Kidney Glomerulus; Membrane Glycoproteins; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; RNA, Messenger; Stilbenes | 2005 |
Bioavailability of trans-resveratrol from red wine in humans.
Topics: Adult; Biological Availability; Chromatography, High Pressure Liquid; Dietary Fats; Fasting; Food; Glucuronides; Humans; Intestinal Absorption; Male; Mass Spectrometry; Resveratrol; Stilbenes; Wine | 2005 |
Trans- and cis-resveratrol increase cytoplasmic calcium levels in A7r5 vascular smooth muscle cells.
Topics: Animals; Aorta; Calcium; Cell Line; Cytoplasm; Drug Synergism; Embryo, Mammalian; Imidazoles; Muscle, Smooth, Vascular; Nickel; Nifedipine; Rats; Resveratrol; Stereoisomerism; Stilbenes; Thapsigargin | 2005 |
Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Female; Inhibitor of Apoptosis Proteins; Mice; Mice, Hairless; Microtubule-Associated Proteins; Neoplasms, Radiation-Induced; Phosphorylation; Repressor Proteins; Resveratrol; RNA, Messenger; Skin Neoplasms; Stilbenes; Survivin; Ultraviolet Rays | 2005 |
Inhibition of influenza A virus replication by resveratrol.
Topics: Animals; Cell Line; Enzyme Inhibitors; Female; Gene Expression; Influenza A virus; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oxidation-Reduction; Resveratrol; Stilbenes; Viral Proteins; Virus Replication | 2005 |
Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Epidermal Growth Factor; Intracellular Signaling Peptides and Proteins; Male; Mice; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Diverse effects of natural antioxidants on cyclosporin cytotoxicity in rat renal tubular cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Cyclosporine; Epithelium; Fluoresceins; Glutathione; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxides; Phenylethyl Alcohol; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Vitamin E | 2005 |
Effects of trans-resveratrol from Polygonum cuspidatum on bone loss using the ovariectomized rat model.
Topics: Absorptiometry, Photon; Alendronate; Analysis of Variance; Animals; Bone and Bones; Bone Density; Calcium; Disease Models, Animal; Fallopia japonica; Female; Femur; Osteoporosis; Ovariectomy; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Weight Gain | 2005 |
Divergent effects of resveratrol, a polyphenolic phytostilbene, on free radical levels and type of cell death induced by the histone deacetylase inhibitors butyrate and trichostatin A.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Butyrates; Cell Death; Cell Line, Tumor; Enzyme Inhibitors; Female; Free Radicals; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Intestinal Mucosa; Kinetics; Mammary Neoplasms, Animal; Mice; Necrosis; Resveratrol; Stilbenes | 2005 |
Magnetic resonance spectroscopic comparison of the effects of resveratrol (3,4',5-trihydroxy stilbene) to conjugated equine estrogen, tibolone and raloxifene on ovariectomized rat brains.
Topics: Animals; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Magnetic Resonance Spectroscopy; Norpregnenes; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2005 |
Does reduction of circulating prostaglandin E2 reduce fetal hypothalamic-pituitary-adrenal axis activity?
Topics: Adrenocorticotropic Hormone; Animals; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Female; Heart Rate, Fetal; Hydrocortisone; Hypothalamo-Hypophyseal System; Maternal-Fetal Exchange; Pituitary-Adrenal System; Placenta; Pregnancy; Pregnancy, Animal; Resveratrol; Sheep; Stilbenes; Sulfonamides | 2005 |
Jasmonates and Na-orthovanadate promote resveratrol production in Vitis vinifera cv. Barbera cell cultures.
Topics: Acetates; Cells, Cultured; Cyclopentanes; Oxylipins; Plant Growth Regulators; Resveratrol; Stilbenes; Time Factors; Vanadates; Vitis | 2005 |
Resveratrol affects X-ray induced apoptosis and cell cycle delay in human cells in vitro.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Extracts; Cell Line; Comet Assay; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Lymphocytes; Resveratrol; S Phase; Stilbenes; Time Factors; Tumor Suppressor Protein p53; X-Rays | 2005 |
Resveratrol reduces ischemia reperfusion injury after experimental testicular torsion.
Topics: Animals; Antioxidants; Male; Models, Animal; Rats; Reperfusion Injury; Resveratrol; Spermatic Cord Torsion; Stilbenes; Vasodilator Agents | 2005 |
Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Binding Sites; Blotting, Northern; Blotting, Western; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hydrogen Peroxide; Luciferases; Male; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transfection | 2005 |
Resveratrol-mediated activation of cAMP response element-binding protein through adenosine A3 receptor by Akt-dependent and -independent pathways.
Topics: Adenosine A3 Receptor Antagonists; Animals; Apoptosis; Biotransformation; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Enzyme Inhibitors; Heart Function Tests; In Situ Nick-End Labeling; Male; Mitogen-Activated Protein Kinases; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
MAGIC-OL Resveratrol.
Topics: Diet; Fruit; Health Promotion; Heart Diseases; Humans; Resveratrol; Stilbenes | 2005 |
[Determination of the contents of resveratrols and piceids in wines by high performance liquid chromatography with solid phase extraction].
Topics: Chromatography, High Pressure Liquid; Glucosides; Indicators and Reagents; Resveratrol; Solid Phase Extraction; Stereoisomerism; Stilbenes; Wine | 2005 |
Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells.
Topics: Animals; Base Sequence; DNA Primers; Enzyme Induction; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Membrane Proteins; PC12 Cells; Phosphorylation; Rats; Repressor Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2005 |
Effect of resveratrol in experimental osteoarthritis in rabbits.
Topics: Animals; Cartilage; Disease Models, Animal; Inflammation; Osteoarthritis; Rabbits; Resveratrol; Stilbenes | 2005 |
Production of stilbenoids from the callus of Arachis hypogaea: a novel source of the anticancer compound piceatannol.
Topics: Antineoplastic Agents; Arachis; Chromatography, High Pressure Liquid; Resveratrol; Stilbenes; Tissue Culture Techniques; Ultraviolet Rays | 2005 |
Determination of stilbenes in hop pellets from different cultivars.
Topics: Chromatography, High Pressure Liquid; Flavonoids; Glucosides; Humulus; Phenols; Polyphenols; Resveratrol; Species Specificity; Stilbenes | 2005 |
[Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons].
Topics: Animals; Disease Models, Animal; Glutamine; Huntington Disease; Mammals; Mutation; Nematoda; Peptides; Resveratrol; Sirtuins; Stilbenes | 2005 |
Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry.
Topics: Antioxidants; Calibration; Chromatography, Liquid; Diet; Glucosides; Glucuronides; Humans; Lipoproteins, LDL; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry | 2005 |
The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).
Topics: Activating Transcription Factor 3; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Chromans; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disulfides; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Male; Mice; Mice, Nude; Microarray Analysis; Neoplasm Invasiveness; Resveratrol; RNA, Messenger; Stilbenes; Sulindac; Thiazolidinediones; Transcription Factors; Transplantation, Heterologous; Troglitazone; Up-Regulation | 2005 |
Resveratrol inhibits Na+ currents in rat dorsal root ganglion neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ganglia, Spinal; Membrane Potentials; NAV1.7 Voltage-Gated Sodium Channel; Neural Inhibition; Neurons, Afferent; Neuropeptides; Nociceptors; Pain; Rats; Resveratrol; Sodium Channels; Stilbenes | 2005 |
Prooxidant activity of resveratrol in the presence of copper ions: mutagenicity in plasmid DNA.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Copper; DNA; DNA Damage; DNA Mutational Analysis; Escherichia coli; Gene Deletion; Guanine; Lac Operon; Mutagens; Oxidants; Plasmids; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2005 |
Resveratrol-Cu(II) induced DNA breakage in human peripheral lymphocytes: implications for anticancer properties.
Topics: Antineoplastic Agents; Comet Assay; Copper; DNA; DNA Damage; Humans; Lymphocytes; Molecular Structure; Plasmids; Reactive Oxygen Species; Resveratrol; Stilbenes | 2005 |
Inhibition of the respiratory burst by resveratrol in human monocytes: correlation with inhibition of PI3K signaling.
Topics: Acridines; Extracellular Signal-Regulated MAP Kinases; Fluorescent Dyes; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Signal Transduction; Stilbenes; U937 Cells | 2005 |
Chronic administration of resveratrol prevents biochemical cardiovascular changes in fructose-fed rats.
Topics: Administration, Oral; Animal Feed; Animals; Antioxidants; Arteriosclerosis; Biomarkers; Blood Pressure; Follow-Up Studies; Fructose; Heart Ventricles; Hypertension; Insulin Resistance; Lipid Peroxidation; Male; Mesenteric Arteries; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Resveratrol; Risk Factors; Spectrophotometry; Stilbenes; Sweetening Agents; Thiobarbituric Acid Reactive Substances; Time Factors | 2005 |
Estimation of trans-resveratrol in herbal extracts and dosage forms by high-performance thin-layer chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dosage Forms; Plant Extracts; Plant Preparations; Resveratrol; Statistics as Topic; Stilbenes | 2005 |
Resveratrol may reduce oxidative stress induced by platinum compounds in human plasma, blood platelets and lymphocytes.
Topics: Antineoplastic Agents; Antioxidants; Blood; Blood Platelets; Cell Survival; Cells, Cultured; Cisplatin; Comet Assay; Dinoprost; DNA Damage; Humans; Lipid Peroxidation; Lymphocytes; Male; Oxidative Stress; Oxidoreductases; Plasma; Platinum Compounds; Reactive Oxygen Species; Resveratrol; Selenium Compounds; Stilbenes | 2005 |
Resveratrol and curcumin reduce the respiratory burst of Chlamydia-primed THP-1 cells.
Topics: Antioxidants; Apoptosis; Cell Line; Chlamydophila pneumoniae; Curcumin; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Macrophages; NADPH Oxidases; Respiratory Burst; Resveratrol; Stilbenes | 2005 |
Analysis of trans-resveratrol by laser ionization mass spectrometry and HPLC with fluorescence detection. Comparison between both techniques.
Topics: Chromatography, High Pressure Liquid; Plant Leaves; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Vitis | 2005 |
Determination of the phytoalexin resveratrol (3,5,4'-trihydroxystilbene) in peanuts and pistachios by high-performance liquid chromatographic diode array (HPLC-DAD) and gas chromatography-mass spectrometry (GC-MS).
Topics: Arachis; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Genotype; Phytoalexins; Pistacia; Plant Extracts; Resveratrol; Seeds; Sesquiterpenes; Stilbenes; Terpenes | 2005 |
FcepsilonRI cross-linking activates a type II phosphatidylinositol 4-kinase in RBL 2H3 cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; beta-Cyclodextrins; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Cells, Cultured; Cholesterol; Enzyme Inhibitors; Hypersensitivity, Immediate; Mast Cells; Membrane Microdomains; Rats; Receptors, IgE; Resveratrol; Stilbenes | 2005 |
Immunosuppression by combined use of cyclosporine and resveratrol in a rat liver transplantation model.
Topics: Animals; Antioxidants; Cyclosporine; Drug Therapy, Combination; Graft Survival; Immunosuppression Therapy; Liver Transplantation; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Rats, Wistar; Resveratrol; Stilbenes | 2005 |
Potential mechanism of blood vessel protection by resveratrol, a component of red wine.
Topics: Animals; Aorta; Cells, Cultured; Color; Electrophoretic Mobility Shift Assay; Heme Oxygenase-1; Male; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; NF-kappa B; Promoter Regions, Genetic; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wine | 2005 |
Relationship between vasodilation capacity and phenolic content of Spanish wines.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Catechin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endothelium, Vascular; Flavonoids; In Vitro Techniques; Kaempferols; Male; Phenols; Polyphenols; Quercetin; Rats; Rats, Wistar; Resveratrol; Rutin; Spain; Stilbenes; Vasodilation; Vasodilator Agents; Wine | 2005 |
Does resveratrol prevent free radical-induced acute pancreatitis?
Topics: Acute Disease; Amylases; Animals; Antioxidants; Diethylstilbestrol; Free Radicals; Male; Pancreatitis; Rats; Rats, Wistar; Resveratrol; Stilbenes; tert-Butylhydroperoxide | 2005 |
Resveratrol inhibits neuronal discharges in rat hippocampal CA1 area.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Electrophysiology; Glutamic Acid; Hippocampus; Male; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Effects of resveratrol on delayed afterdepolarization and triggered activity induced by ouabain in guinea pig papillary muscles.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Guinea Pigs; Male; Microelectrodes; Ouabain; Papillary Muscles; Resveratrol; Stilbenes | 2005 |
Production of ex vivo lipopolysaccharide-induced tumor necrosis factor-alpha, interleukin-1beta, and interleukin-6 is suppressed by trans-resveratrol in a concentration-dependent manner.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Immunologic; Enzyme-Linked Immunosorbent Assay; Interleukin-1; Interleukin-6; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2005 |
Chemopreventive properties of trans-resveratrol against the cytotoxicity of chloroacetanilide herbicides in vitro.
Topics: Acetamides; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Chlorocebus aethiops; Flow Cytometry; Herbicides; Humans; Receptors, Estrogen; Resveratrol; Stilbenes; Toluidines; Vero Cells | 2005 |
Fungicidal effect of resveratrol on human infectious fungi.
Topics: Antifungal Agents; Candida albicans; Hemolysis; Humans; Microbial Sensitivity Tests; Resveratrol; Stilbenes | 2005 |
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA-Binding Proteins; Female; Humans; Ovarian Neoplasms; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Resveratrol; Ribonucleotide Reductases; S Phase; Signal Transduction; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrosine | 2005 |
Inhibition of melanoma cell proliferation by resveratrol is correlated with upregulation of quinone reductase 2 and p53.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Quinone Reductases; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography.
Topics: Animals; Cell Line, Tumor; Fluorine Radioisotopes; Humans; Male; Models, Animal; Molecular Structure; Positron-Emission Tomography; Rats; Rats, Wistar; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes; Tumor Cells, Cultured | 2005 |
Determination of stilbenes (delta-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, epsilon-viniferin) in Brazilian wines.
Topics: Benzofurans; Brazil; Chromatography, High Pressure Liquid; Glucosides; Magnetic Resonance Spectroscopy; Resorcinols; Resveratrol; Stilbenes; Wine | 2005 |
Activity of NADPH-cytochrome P-450 reductase of the human heart, liver and lungs in the presence of (-)-epigallocatechin gallate, quercetin and resveratrol: an in vitro study.
Topics: Anti-Bacterial Agents; Antioxidants; Catechin; Diet; Doxorubicin; Enzyme Activation; Heart; Herbicides; Humans; In Vitro Techniques; Liver; Lung; Male; Microsomes, Liver; Myocardium; NADPH-Ferrihemoprotein Reductase; Paraquat; Quercetin; Resveratrol; Stilbenes | 2005 |
Effects of resveratrol, raloxifene, tibolone and conjugated equine estrogen on vaginal squamous cell maturation of ovariectomized rats.
Topics: Animals; Epithelial Cells; Estrogens, Conjugated (USP); Female; Norpregnenes; Ovariectomy; Ovary; Papanicolaou Test; Raloxifene Hydrochloride; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vagina; Vaginal Smears | 2005 |
Resveratrol inhibits rhabdomyosarcoma cell proliferation.
Topics: Anticarcinogenic Agents; Biopsy, Needle; Blotting, Western; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Immunohistochemistry; Resveratrol; Rhabdomyosarcoma; Risk Factors; Sensitivity and Specificity; Stilbenes; Tumor Cells, Cultured | 2005 |
Resveratrol regulates insulin-like growth factor-II in breast cancer cells.
Topics: Angiogenesis Inhibitors; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Female; Humans; Insulin-Like Growth Factor II; Resveratrol; RNA, Messenger; Stilbenes | 2005 |
Resveratrol inhibits polyphosphoinositide metabolism in activated platelets.
Topics: Blood Platelets; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Cells, Cultured; Down-Regulation; Humans; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphotransferases (Alcohol Group Acceptor); Platelet Activation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Thrombin; Transferases (Other Substituted Phosphate Groups) | 2005 |
Protective effect of resveratrol against renal oxidative stress in cholestasis.
Topics: Animals; Antioxidants; Biopsy, Needle; Cholestasis; Disease Models, Animal; Female; Immunohistochemistry; Injections, Intraperitoneal; Kidney Diseases; Ligation; Male; Oxidative Stress; Primary Prevention; Probability; Random Allocation; Rats; Rats, Inbred Strains; Resveratrol; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric; Stilbenes; Survival Rate | 2005 |
The chemopreventive agent resveratrol stimulates cyclic AMP-dependent chloride secretion in vitro.
Topics: Animals; Anticarcinogenic Agents; Butyrates; Cell Differentiation; Cell Line, Tumor; Chlorides; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Humans; In Vitro Techniques; Jejunum; Male; Mice; Mice, Inbred BALB C; Resveratrol; Signal Transduction; Stilbenes; Time Factors | 2005 |
Resveratrol modulates gene expression associated with apoptosis, proliferation and cell cycle in cells with mutated human c-Ha-Ras, but does not alter c-Ha-Ras mRNA or protein expression.
Topics: Animals; Apoptosis; Base Sequence; Cell Cycle; Cell Line; Cell Proliferation; Gene Expression; Genes, p53; Genes, ras; Humans; Mice; Mutation; ras Proteins; Resveratrol; RNA, Messenger; Stilbenes | 2005 |
Protective effect of resveratrol against oxidative stress in cholestasis.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cholestasis; Chronic Disease; Cytokines; Cytoprotection; Glutathione; Injections, Intraperitoneal; Liver; Liver Cirrhosis, Biliary; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Resveratrol; Stilbenes | 2005 |
Effect of resveratrol on matrix metalloproteinase-2 (MMP-2) and Secreted Protein Acidic and Rich in Cysteine (SPARC) on human cultured glioblastoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Glioblastoma; Humans; Matrix Metalloproteinase 2; Osteonectin; Resveratrol; RNA, Messenger; Stilbenes | 2005 |
Caffeic acid phenethyl ester (CAPE) prevents transformation of human cells by arsenite (As) and suppresses growth of As-transformed cells.
Topics: Antioxidants; Apoptosis; Arsenites; Caffeic Acids; Catechin; Cell Growth Processes; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cytokines; Drug Interactions; Flow Cytometry; Humans; Oligonucleotide Array Sequence Analysis; Osteosarcoma; Phenylethyl Alcohol; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2005 |
Resveratrol induces apoptosis and differentiation in acute promyelocytic leukemia (NB4) cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Proliferation; DNA Damage; Humans; Leukemia, Promyelocytic, Acute; Resveratrol; Stilbenes; Tretinoin; Tumor Cells, Cultured | 2005 |
Effect of resveratrol on angiogenesis and platelet/fibrin-accelerated tumor growth in the chick chorioallantoic membrane model.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line; Chick Embryo; Chorioallantoic Membrane; Colonic Neoplasms; Endothelium, Vascular; Fibroblast Growth Factor 2; Fibrosarcoma; Flavonoids; Humans; Neovascularization, Pathologic; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2005 |
Resveratrol prolongs allograft survival after liver transplantation in rats.
Topics: Animals; Graft Survival; Immunosuppressive Agents; Liver Transplantation; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Rats, Wistar; Resveratrol; Stilbenes; T-Lymphocytes; Transplantation, Homologous | 2005 |
Resveratrol, a polyphenolic compound in red wine, protects against oxidized LDL-induced cytotoxicity in endothelial cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Calcium; Caspase 3; Caspases; Catalase; Cell Survival; Cells, Cultured; Cytochromes c; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Flavonoids; Flow Cytometry; Humans; In Situ Nick-End Labeling; Intracellular Space; Lipoproteins, LDL; Membrane Potentials; Microscopy, Fluorescence; Mitochondrial Membranes; Phenols; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Wine | 2006 |
In vitro polyphenol effects on activity, expression and secretion of pancreatic bile salt-dependent lipase.
Topics: alpha-Amylases; Animals; Cell Line, Tumor; Flavonoids; Humans; Pancreas; Phenols; Polyphenols; Rats; Resveratrol; RNA, Messenger; Sterol Esterase; Stilbenes; Wine | 2005 |
A proposed molecular basis for the selective resveratrol inhibition of the PGHS-1 peroxidase activity.
Topics: Binding Sites; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Models, Molecular; Peroxidases; Protein Structure, Tertiary; Resveratrol; Stilbenes; Substrate Specificity | 2005 |
Resveratrol inhibits type II phosphatidylinositol 4-kinase: a key component in pathways of phosphoinositide turn over.
Topics: 1-Phosphatidylinositol 4-Kinase; Cell Adhesion; Cell Line; Cloning, Molecular; Enzyme Activation; Enzyme Inhibitors; Humans; Jurkat Cells; Phosphatidylinositols; Resveratrol; Stilbenes | 2005 |
The red wine polyphenol, resveratrol, exerts acute direct actions on guinea-pig ventricular myocytes.
Topics: Animals; Calcium; Cell Size; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Guinea Pigs; Heart Ventricles; Intracellular Space; Male; Membrane Potentials; Myocytes, Cardiac; Phenols; Polyphenols; Resveratrol; Stilbenes; Vasodilator Agents; Ventricular Function; Wine | 2005 |
Simple and rapid method for cis- and trans-resveratrol and piceid isomers determination in wine by high-performance liquid chromatography using chromolith columns.
Topics: Chromatography, High Pressure Liquid; Glucosides; Resveratrol; Stereoisomerism; Stilbenes; Wine | 2005 |
[Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].
Topics: Anthraquinones; Emodin; Glucosides; Plant Roots; Plants, Medicinal; Principal Component Analysis; Quality Control; Resveratrol; Rumex; Seasons; Stilbenes | 2005 |
Protective effects of resveratrol against oxidative/nitrative modifications of plasma proteins and lipids exposed to peroxynitrite.
Topics: Blood Proteins; Deferoxamine; Humans; Lipid Peroxidation; Lipids; Oxidation-Reduction; Peroxynitrous Acid; Resveratrol; Stilbenes; Tyrosine | 2006 |
Trans-resveratrol, a red wine ingredient, inhibits voltage-activated potassium currents in rat hippocampal neurons.
Topics: Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Hippocampus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Inhibition of cyclo-oxygenase-2 expression in mouse macrophages by 4-(3-methyl-but-1-enyl)-3,5,3',4'-tetrahydroxystilbene, a resveratrol derivative from peanuts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachis; Blotting, Western; Cyclooxygenase Inhibitors; Lipopolysaccharides; Macrophages; Mice; Phytotherapy; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Resveratrol; RNA, Messenger; Seeds; Stilbenes | 2005 |
Optimization of solid-phase extraction using artificial neural networks in combination with experimental design for determination of resveratrol by capillary zone electrophoresis in wines.
Topics: Chemical Fractionation; Electrophoresis, Capillary; Multivariate Analysis; Neural Networks, Computer; Resveratrol; Stilbenes; Wine | 2005 |
Specific inhibition of MyD88-independent signaling pathways of TLR3 and TLR4 by resveratrol: molecular targets are TBK1 and RIP1 in TRIF complex.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Antigens, Differentiation; Cell Line; Cyclooxygenase 2; GTPase-Activating Proteins; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Poly I-C; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Receptors, Cell Surface; Receptors, Immunologic; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptors | 2005 |
Effect of resveratrol on herpes simplex virus vaginal infection in the mouse.
Topics: Animals; Antiviral Agents; Drug Evaluation, Preclinical; Female; Herpes Genitalis; Herpesvirus 1, Human; Herpesvirus 2, Human; Mice; Placebos; Resveratrol; Stilbenes; Survival Analysis; Vaginal Diseases; Viral Plaque Assay; Virus Replication | 2005 |
Dosage effects of resveratrol on ethanol-induced cell death in the human K562 cell line.
Topics: Adenosine Triphosphate; Apoptosis; Caspase 3; Caspases; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Ethanol; Humans; K562 Cells; L-Lactate Dehydrogenase; MAP Kinase Kinase 4; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors | 2006 |
Triacylglycerol-mediated oxidative stress inhibits nitric oxide production in rat isolated hepatocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Nucleus; Cells, Cultured; Emulsions; Hepatocytes; Lipid Metabolism; Lipids; Nitric Oxide; Nitrites; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha | 2005 |
Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Atherosclerosis; Body Weight; Cholesterol, Dietary; Dose-Response Relationship, Drug; Ethanol; Femoral Artery; Hypercholesterolemia; Lipids; Male; Rabbits; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents; Wine | 2005 |
[Preliminary study on anti-tumor function of resveratrol and its immunological mechanism].
Topics: Animals; Antibody Formation; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; Interleukin-2; Interleukin-8; Laryngeal Neoplasms; Mice; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2005 |
Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation.
Topics: Animals; Antioxidants; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Drug Antagonism; Endothelium, Vascular; Gene Expression; Intercellular Adhesion Molecule-1; Interleukin-6; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Quercetin; rac1 GTP-Binding Protein; Resveratrol; S-Nitroso-N-Acetylpenicillamine; STAT3 Transcription Factor; Stilbenes; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Resveratrol suppresses interferon-gamma-induced biochemical pathways in human peripheral blood mononuclear cells in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Ionophores; Kynurenine; Monocytes; Neopterin; Phytohemagglutinins; Resveratrol; Stilbenes; Tryptophan; Tumor Necrosis Factor-alpha | 2005 |
Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cell Line; Gene Expression Regulation; Humans; Molecular Structure; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Quercetin; Resveratrol; Stilbenes; Wine | 2005 |
Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress.
Topics: Aldehydes; Animals; Antioxidants; Aorta; Catalase; Cells, Cultured; Cytoprotection; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Isoenzymes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Up-Regulation; Wine; Xanthine Oxidase | 2006 |
Enhancement of NF-kappaB activity by resveratrol in cytokine-exposed mesangial cells.
Topics: Alkaline Phosphatase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Line, Tumor; Chemokine CCL2; Cytokines; Gene Expression Regulation; Glomerulonephritis; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Kidney Glomerulus; Male; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2005 |
Polyphenol interaction with the T47D human breast cancer cell line.
Topics: Breast Neoplasms; Catechin; Cell Cycle; Cell Division; Cell Line, Tumor; Flavonoids; Humans; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Phenols; Polyphenols; Quercetin; Resveratrol; S Phase; Stilbenes; Wine | 2005 |
SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Bromodeoxyuridine; Cells, Cultured; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Immunohistochemistry; Lentivirus; Lysine; Microglia; Microscopy, Fluorescence; Models, Biological; Models, Genetic; Neurons; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2005 |
Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Homocysteine; Humans; Leukocytes; Resveratrol; Stilbenes | 2005 |
Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor.
Topics: Animals; Collagen; Coronary Circulation; Coronary Vessels; Drug Combinations; Endothelial Cells; Heart Ventricles; Heme Oxygenase-1; Humans; In Vitro Techniques; Laminin; Male; Metalloporphyrins; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Organ Size; Proteoglycans; Protoporphyrins; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thioredoxins; Vascular Endothelial Growth Factor A | 2005 |
[Research on resveratrol's effects on suppressing growth and inducing apoptosis of GBC cells].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Gallbladder Neoplasms; Humans; Immunohistochemistry; Mice; Plants, Medicinal; Resveratrol; Stilbenes | 2005 |
A validated HPLC method for the quantitative analysis of trans-resveratrol and trans-piceid in Hungarian wines.
Topics: Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Glucosides; Mass Spectrometry; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Wine | 2005 |
The grape component resveratrol interferes with the function of chemoattractant receptors on phagocytic leukocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Calcium; Chemokine CXCL12; Chemokines, CXC; Chemotactic Factors; Chemotaxis, Leukocyte; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-8; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Phagocytes; Receptors, Formyl Peptide; Resveratrol; Stilbenes; Superoxides; Vitis | 2004 |
Resveratrol reduces intracellular free calcium concentration in rat ventricular myocytes.
Topics: Animals; Calcium; Calcium Channels; Heart Ventricles; Intracellular Fluid; Male; Myocytes, Cardiac; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Resveratrol; Sarcoplasmic Reticulum; Stilbenes | 2005 |
Resveratrol-induced apoptosis is enhanced in acute lymphoblastic leukemia cells by modulation of the mitochondrial permeability transition pore.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Isoquinolines; Jurkat Cells; Membrane Potentials; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Hypoxia; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Stilbenes; Tongue Neoplasms; Transcriptional Activation; Vascular Endothelial Growth Factors | 2005 |
A study of mechanisms involved in vasodilatation induced by resveratrol in isolated porcine coronary artery.
Topics: Animals; Calcium; Coronary Circulation; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Potassium Chloride; Prostaglandins; Receptors, Adrenergic, beta; Resveratrol; Serotonin; Serotonin Agents; Stilbenes; Swine; Vasodilation; Vasodilator Agents | 2006 |
Effects of resveratrol in storage solution on adhesion molecule expression and nitric oxide synthesis in vein grafts.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion Molecules; Coronary Artery Bypass; Humans; Nitric Oxide; Peroxidase; Resveratrol; Saphenous Vein; Stilbenes | 2005 |
Identification of the major metabolites of resveratrol in rat urine by HPLC-MS/MS.
Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2005 |
[Effects of resveratrol on isolated thoracic aorta rings of rats].
Topics: Animals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelium, Vascular; Female; Glyburide; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents | 2005 |
Effect of some phenolic compounds and beverages on pepsin activity during simulated gastric digestion.
Topics: Animals; Caseins; Catechin; Digestion; Enzyme Activation; Flavonoids; Gastric Mucosa; Hemoglobins; Kinetics; Meat; Pepsin A; Phenols; Polyphenols; Protein Denaturation; Quercetin; Resveratrol; Stilbenes; Swine; Tea; Wine | 2005 |
Role of peptide primary sequence in polyphenol-protein recognition: an example with neurotensin.
Topics: Amino Acid Sequence; Flavonoids; Glucosides; Hydrolyzable Tannins; Models, Molecular; Neurotensin; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phenols; Polyphenols; Proteins; Protons; Resveratrol; Stilbenes | 2005 |
Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II).
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Binding Sites; Cations, Divalent; Copper; DNA; DNA Damage; Hydroxyl Radical; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship | 2006 |
Synthesis of a resveratrol analogue with high ceramide-mediated proapoptotic activity on human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Ceramides; Drug Screening Assays, Antitumor; Female; Humans; Resveratrol; Stilbenes; Structure-Activity Relationship | 2005 |
Resveratrol may reduce apoptosis of rat testicular germ cells after experimental testicular torsion.
Topics: Animals; Apoptosis; Immunohistochemistry; Male; Rats; Rats, Wistar; Resveratrol; Spermatic Cord Torsion; Spermatozoa; Statistics, Nonparametric; Stilbenes; Testis | 2005 |
[The effects of resveratrol on the activation, proliferation and cytokine expression of murine T lymphocytes].
Topics: Animals; Cell Proliferation; Cells, Cultured; Cytokines; Flow Cytometry; Gene Expression; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Male; Mice; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; T-Lymphocytes | 2005 |
A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.
Topics: Animals; Asparagine; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Endoplasmic Reticulum; Fungal Proteins; Gene Expression Profiling; Glutamine; Heat-Shock Proteins; Longevity; Resveratrol; RNA Interference; Sirtuins; Stilbenes; Transcription, Genetic | 2005 |
Mechanism of induction of muscle protein degradation by angiotensin II.
Topics: Active Transport, Cell Nucleus; Angiotensin I; Angiotensin II; Animals; Blood Proteins; Cell Line; Enzyme Activation; I-kappa B Kinase; Luciferases; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Naphthalenes; NF-kappa B; Proteasome Endopeptidase Complex; Protein Kinase C; Proteoglycans; Resveratrol; Signal Transduction; Stilbenes; Transcriptional Activation | 2006 |
Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation.
Topics: Apoptosis; Calcitriol; Carrier Proteins; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Macrophage Colony-Stimulating Factor; Membrane Glycoproteins; Multiple Myeloma; Osteoblasts; Osteocalcin; Osteoclasts; Osteopontin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Calcitriol; Resveratrol; Sialoglycoproteins; Stilbenes | 2005 |
Phytoestrogen resveratrol suppresses steroidogenesis by rat adrenocortical cells by inhibiting cytochrome P450 c21-hydroxylase.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Bucladesine; Cells, Cultured; Corticosterone; Male; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Resveratrol; Steroid 21-Hydroxylase; Stilbenes | 2005 |
SIR2 calls upon the ER.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Endoplasmic Reticulum; Forkhead Transcription Factors; Homeodomain Proteins; Longevity; Membrane Proteins; Resveratrol; Sirtuins; Stilbenes; Transcription Factors | 2005 |
Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: involvement of cyclooxygenases and heat shock protein 70.
Topics: Animals; Ceruletide; Cyclooxygenase Inhibitors; Edema; HSP70 Heat-Shock Proteins; Interleukin-1; Interleukin-10; Ischemic Preconditioning; Lactones; Male; Pancreatitis; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfones | 2005 |
Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin-resveratrol hybrids.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Coumarins; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Structure; Muscle, Smooth, Vascular; Norepinephrine; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Resveratrol; Stilbenes; Thrombin; Time Factors; Vasodilator Agents; Vasomotor System | 2006 |
Oxidation of dietary polyphenolics by hydroperoxidase activity of lipoxygenase.
Topics: Flavanones; Flavonoids; Glutathione; Hydrogen Peroxide; Lipoxygenase; Oxidation-Reduction; Peroxidase; Phenols; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2005 |
High salt culture conditions suppress proliferation of rat C6 glioma cell by arresting cell-cycle progression at S-phase.
Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Culture Media; Early Growth Response Protein 1; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Glioma; Hypertonic Solutions; Irinotecan; Osmolar Concentration; Rats; Resveratrol; S Phase; Sodium Chloride; Stilbenes | 2005 |
Resveratrol, a polyphenolic phytoalexin, attenuates diabetic nephropathy in rats.
Topics: Animals; Antioxidants; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glutathione; Kidney; Kidney Function Tests; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Phenols; Phytoalexins; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Stilbenes; Superoxide Dismutase; Terpenes | 2006 |
Preparative isolation and purification of five compounds from the Chinese medicinal herb Polygonum cuspidatum Sieb. et Zucc by high-speed counter-current chromatography.
Topics: Anthracenes; Chromatography, High Pressure Liquid; Countercurrent Distribution; Emodin; Fallopia japonica; Glucosides; Glycosides; Molecular Structure; Plant Preparations; Reproducibility of Results; Resveratrol; Stilbenes | 2005 |
Resveratrol, a natural red wine polyphenol, reduces ischemia-reperfusion-induced spinal cord injury.
Topics: Animals; Male; Phenols; Rabbits; Reperfusion Injury; Resveratrol; Spinal Cord Injuries; Stilbenes; Wine | 2005 |
Invited commentary.
Topics: Animals; Phenols; Rabbits; Reperfusion Injury; Resveratrol; Spinal Cord Injuries; Stilbenes; Wine | 2005 |
Resveratrol inhibits gentamicin-induced mesangial cell contraction.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Cell Size; Cells, Cultured; Enzyme Inhibitors; Gentamicins; Glomerular Mesangium; Muscle Contraction; Muscle, Smooth; NADP; NADPH Oxidases; Rats; Resveratrol; Stilbenes | 2006 |
Protective effect of nitric oxide pathway in resveratrol renal ischemia-reperfusion injury in rats.
Topics: Angiogenesis Inhibitors; Animals; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits TNF-alpha-induced proliferation and matrix metalloproteinase expression in human vascular smooth muscle cells.
Topics: Angiogenesis Inhibitors; Aorta; Cell Cycle; Cell Division; Cells, Cultured; Genes, Reporter; Humans; Matrix Metalloproteinase 9; Metalloproteases; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Promoter Regions, Genetic; Resveratrol; Stilbenes; Transfection; Tumor Necrosis Factor-alpha | 2005 |
The introduction of the stilbene synthase gene enhances the natural antiradical activity of Lycopersicon esculentum mill.
Topics: Acyltransferases; Animals; Antioxidants; Apoptosis; Diet; Electron Spin Resonance Spectroscopy; Free Radicals; Lipid Peroxidation; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Oxidative Stress; Plants, Genetically Modified; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Solanum lycopersicum; Stilbenes | 2006 |
Resveratrol reduces the elevated level of MMP-9 induced by cerebral ischemia-reperfusion in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Cortex; Disease Models, Animal; Gene Expression; Ischemic Attack, Transient; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neuroprotective Agents; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stroke | 2006 |
Resveratrol protects against 4-hydroxynonenal-induced apoptosis by blocking JNK and c-JUN/AP-1 signaling.
Topics: Aldehydes; Animals; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Caspases; Cytochromes c; Dose-Response Relationship, Drug; Drug Antagonism; Fibroblasts; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mitochondria; Resveratrol; Signal Transduction; Stilbenes; Swiss 3T3 Cells; Transcription Factor AP-1 | 2006 |
Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Caspases; Cold Temperature; Cytochromes c; Dose-Response Relationship, Drug; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Mitochondria, Liver; Mitochondrial Membranes; Mitochondrial Swelling; Necrosis; Oxidative Phosphorylation; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; Resveratrol; Stilbenes; Time Factors | 2005 |
Possible role of nitric oxide in the protective effect of resveratrol in 5/6th nephrectomized rats.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Pressure; Body Weight; Disease Models, Animal; Eating; Enzyme Inhibitors; Kidney Function Tests; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Proteinuria; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Resveratrol; Stilbenes; Survival Rate | 2006 |
Synthesis and anti-inflammatory activity of resveratrol analogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzene Derivatives; Ear, External; Edema; Indicators and Reagents; Mannich Bases; Mice; Pyridines; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2005 |
Chemopreventive effect of trans-resveratrol--a phytoalexin against colonic aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine induced colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antigens, Nuclear; Carcinogens; Cell Proliferation; Colon; Colonic Neoplasms; Enzyme Inhibitors; Intestinal Mucosa; Male; Nuclear Proteins; Phytoalexins; Plant Extracts; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Thiobarbituric Acid Reactive Substances | 2006 |
Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Coronary Vessels; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 4; Interleukin-1; Muscle, Smooth, Vascular; Pregnancy-Associated Plasma Protein-A; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Vitis; Wine | 2006 |
The grape-derived polyphenol resveratrol differentially affects epidermal and platelet-derived growth factor signaling in human liver myofibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Fibroblast Growth Factors; Fibroblasts; Flavonoids; Humans; Liver; Liver Cirrhosis; Myoblasts; Phenols; Platelet-Derived Growth Factor; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Vitis | 2006 |
Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Resveratrol; Stilbenes; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2006 |
Antiproliferative and antiangiogenic effects of 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, in human umbilical vascular endothelial cells.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Capillaries; Cattle; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Cytochrome P-450 CYP1A1; DNA Replication; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Flow Cytometry; Focal Adhesion Protein-Tyrosine Kinases; G1 Phase; Growth Inhibitors; Humans; Methylcholanthrene; Phosphorylation; Receptors, Aryl Hydrocarbon; Resting Phase, Cell Cycle; Resveratrol; Serum Albumin, Bovine; Signal Transduction; Stilbenes; Thymidine; Time Factors; Tritium; Tumor Necrosis Factor-alpha; Umbilical Veins; Up-Regulation | 2006 |
Elicitation of resveratrol in peanut kernels by application of abiotic stresses.
Topics: Antioxidants; Arachis; Chromatography, High Pressure Liquid; Indicators and Reagents; Phenolphthaleins; Phenols; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Ultrasonics | 2005 |
Time-dependent resveratrol-mediated mRNA and protein expression associated with cell cycle in WR-21 cells containing mutated human c-Ha-Ras.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cyclin G; Cyclin G1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression; Genes, p53; Genes, ras; Humans; Mice; Mutation; Proto-Oncogene Proteins c-mdm2; Resveratrol; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salivary Gland Neoplasms; Stilbenes; Time Factors; Tumor Suppressor Protein p53 | 2006 |
Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor.
Topics: DNA-(Apurinic or Apyrimidinic Site) Lyase; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Melanocytes; Melanoma; Recombinant Proteins; Resveratrol; Stilbenes | 2005 |
Resveratrol inhibits vascular smooth muscle cell proliferation and induces apoptosis.
Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Antioxidants; Aorta, Thoracic; Apoptosis; Blotting, Western; Cattle; Cell Proliferation; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Flow Cytometry; In Situ Nick-End Labeling; In Vitro Techniques; Muscle, Smooth, Vascular; Proliferating Cell Nuclear Antigen; Resveratrol; Stilbenes | 2005 |
Role of nitric oxide in resveratrol-induced renal protective effects of ischemic preconditioning.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Ischemic Preconditioning; Kidney; Kidney Diseases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2005 |
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Cyclooxygenase 2; Diet; Injections, Subcutaneous; Isothiocyanates; Male; Membrane Proteins; Mesocricetus; Neoplasms, Experimental; Nitrosamines; Pancreatic Neoplasms; Resveratrol; Stilbenes; Sulfoxides; Thiocyanates | 2006 |
Effect of resveratrol on peritoneal macrophages in rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Culture Media; Disease Models, Animal; Interleukin-1; Macrophages, Peritoneal; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Pancreatitis; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Systemic Inflammatory Response Syndrome; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Modified cyclodextrins are chemically defined glucan inducers of defense responses in grapevine cell cultures.
Topics: beta-Cyclodextrins; Botrytis; Cells, Cultured; Cyclodextrins; Isoenzymes; Kinetics; Peroxidase; Phytoalexins; Plant Extracts; Plant Stems; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Vitis | 2006 |
Encapsulating drugs in biodegradable ultrafine fibers through co-axial electrospinning.
Topics: Anti-Bacterial Agents; Antioxidants; Biocompatible Materials; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Electrochemistry; Gentamicins; Materials Testing; Microscopy, Electron; Nanostructures; Polyesters; Resveratrol; Stilbenes | 2006 |
Insulin-like growth factor II mediates resveratrol stimulatory effect on cathepsin D in breast cancer cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cathepsin D; Cell Line, Tumor; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor II; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Resveratrol; RNA, Messenger; Stilbenes | 2006 |
Resveratrol enhances radiosensitivity of human non-small cell lung cancer NCI-H838 cells accompanied by inhibition of nuclear factor-kappa B activation.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; NF-kappa B; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Stilbenes | 2005 |
Resveratrol mimics ischemic preconditioning in the brain.
Topics: Animals; Antioxidants; Cell Death; Glucose; Hippocampus; Hypoxia, Brain; Ischemic Preconditioning; Neuroprotective Agents; Organ Culture Techniques; Propidium; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
An improved synthesis of resveratrol.
Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Resveratrol; Stilbenes | 2006 |
Resveratrol, a natural ingredient of grape skin: antiarrhythmic efficacy and ionic mechanisms.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relationship, Drug; Fruit; Guinea Pigs; Ion Channel Gating; Muscle Cells; Plant Extracts; Rats; Rats, Wistar; Resveratrol; Stilbenes; Survival Rate; Treatment Outcome; Vitis | 2006 |
[Recent development and future direction of anti-aging therapy by supplements].
Topics: Aging; Antioxidants; Curcumin; Dietary Supplements; Forecasting; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2005 |
Effect of resveratrol on L-type calcium current in rat ventricular myocytes.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Heart Ventricles; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vanadates | 2006 |
Plant polyphenols mobilize endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage: a putative mechanism for anticancer properties.
Topics: Antineoplastic Agents; Antioxidants; Chelating Agents; Comet Assay; Copper; DNA Damage; Flavonoids; Gallic Acid; Humans; Lymphocytes; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2006 |
Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds.
Topics: Benzhydryl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Proliferation; Chlordecone; Cyclic AMP Response Element-Binding Protein; Diethylstilbestrol; Dose-Response Relationship, Drug; eIF-2 Kinase; Endosulfan; Estradiol; Estrogens; Female; Humans; Mitogen-Activated Protein Kinase Kinases; Phenols; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes; Structure-Activity Relationship; Transcription Factors; Transfection; Tumor Cells, Cultured | 2006 |
Proteomics analysis of the actions of grape seed extract in rat brain: technological and biological implications for the study of the actions of psychoactive compounds.
Topics: Animals; Brain; Brain Chemistry; Catechin; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Genistein; Image Processing, Computer-Assisted; Mass Spectrometry; Nerve Tissue Proteins; Peptide Mapping; Plant Extracts; Proteomics; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitis | 2006 |
Sulfation of resveratrol in human liver: evidence of a major role for the sulfotransferases SULT1A1 and SULT1E1.
Topics: Adolescent; Adult; Aged; Arylsulfotransferase; Chromatography, Liquid; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Middle Aged; Protein Isoforms; Recombinant Proteins; Resveratrol; Stilbenes; Sulfates; Sulfotransferases | 2005 |
Rapid synthesis of triazole-modified resveratrol analogues via click chemistry.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Triazoles | 2006 |
Resveratrol induces apoptosis of human malignant B cells by activation of caspase-3 and p38 MAP kinase pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Lymphoma, B-Cell; Multiple Myeloma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Stilbenes | 2006 |
Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Glucose; Glycogen; Hepatocytes; Hyperglycemia; Insulin; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors; Wine | 2006 |
Effect of resveratrol on pancreatic oxygen free radicals in rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Free Radicals; Male; Malondialdehyde; Neutrophils; Oxygen; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2006 |
Effects of trans-resveratrol on hypertension-induced cardiac hypertrophy using the partially nephrectomized rat model.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Agents; Endothelin-1; Hypertension, Renal; Male; Myocardium; Nephrectomy; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
High-performance liquid chromatography spectrometric analysis of trans-resveratrol in rat plasma.
Topics: Animals; Chromatography, High Pressure Liquid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stilbenes | 2006 |
Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1.
Topics: Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; DNA; Heart; Heart Function Tests; Male; Microcirculation; Molecular Structure; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NF-kappa B; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Binding; Rats; Rats, Sprague-Dawley; Resveratrol; Sp1 Transcription Factor; Stilbenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Ventricular Function, Left | 2006 |
Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.
Topics: Aging; Animals; Cognition; Cyprinodontiformes; Dose-Response Relationship, Drug; Locomotion; Longevity; Neurofibrils; Resveratrol; Stilbenes; Survival Analysis | 2006 |
Determination of trans-resveratrol in grapes by pressurised liquid extraction and fast high-performance liquid chromatography.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Methanol; Polystyrenes; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes; Temperature; Vitis | 2006 |
Resveratrol down-regulates the growth and telomerase activity of breast cancer cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Female; Flow Cytometry; Humans; Microscopy, Confocal; Resveratrol; Stilbenes; Telomerase; Time Factors | 2006 |
Resveratrol affects CYP1A expression in rainbow trout hepatocytes.
Topics: Animals; beta-Naphthoflavone; Cells, Cultured; Cycloheximide; Cytochrome P-450 CYP1A1; Dactinomycin; DNA Primers; Enzyme Inhibitors; Gene Expression Regulation; Hepatocytes; Oncorhynchus mykiss; Protein Synthesis Inhibitors; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2006 |
Resveratrol, a natural diphenol, reduces metastatic growth in an experimental cancer model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Carcinoma, Lewis Lung; Cell Line, Tumor; Dose-Response Relationship, Drug; Eating; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Resveratrol; Stilbenes | 2007 |
Resveratrol decreases calcium sensitivity of vascular smooth muscle and enhances cytosolic calcium increase in endothelium.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Mitral Valve; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Potassium Chloride; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cyclooxygenase 2; Electrophoretic Mobility Shift Assay; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; I-kappa B Kinase; Immunohistochemistry; Immunoprecipitation; Mice; Mice, Inbred ICR; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Skin; Stilbenes; Sulfones; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2006 |
The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Gene Expression Regulation; Inflammation; Male; Membrane Proteins; NF-kappa B; Peroxidase; Phytoalexins; Prostaglandin D2; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha; Wine | 2006 |
Modulation of DNA intercalation by resveratrol and genistein.
Topics: Acridine Orange; Anticarcinogenic Agents; Coloring Agents; DNA; DNA Damage; Ethidium; Genistein; Intercalating Agents; Nucleic Acid Conformation; Resveratrol; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stilbenes | 2006 |
Resveratrol is efficiently glucuronidated by UDP-glucuronosyltransferases in the human gastrointestinal tract and in Caco-2 cells.
Topics: Caco-2 Cells; Gastrointestinal Tract; Glucuronides; Glucuronosyltransferase; Humans; Liver; Microsomes; Resveratrol; Stilbenes | 2006 |
Antioxidant activity and inhibition of alpha-glucosidase by trans-resveratrol, piceid, and a novel trans-stilbene from the roots of Israeli Rumex bucephalophorus L.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glucosides; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Plant Roots; Polygonaceae; Resveratrol; Stilbenes | 2006 |
Resveratrol reduces renal and lung injury caused by sepsis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Collagen; Disease Models, Animal; Female; Glutathione; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Ligation; Lung; Lung Diseases; Male; Malondialdehyde; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Sepsis; Stilbenes; Tumor Necrosis Factor-alpha | 2006 |
Bifunctional effect of resveratrol on the expression of ErbB2 in human breast cancer cell.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Nucleus; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Mutation; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Receptor, ErbB-2; Receptors, Growth Factor; Resveratrol; Stilbenes; Transcription Factor AP-2 | 2006 |
Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis.
Topics: Apoptosis; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Nucleus; DNA Replication; Humans; Multiple Myeloma; Neoplasm Invasiveness; NF-kappa B; Resveratrol; Stilbenes | 2006 |
[Research of a new kind of biological response modifier to anti-laryngocarcinoma].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Humans; Interleukin-2; Interleukin-8; Laryngeal Neoplasms; Male; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2005 |
Beneficial effect of resveratrol on cholecystokinin-induced experimental pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Body Weight; Calcium; Catalase; Creatinine; Glutathione; Glutathione Peroxidase; Immunohistochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Lipase; Liver; Male; NF-kappa B; Nitric Oxide Synthase Type III; Organ Size; Pancreas; Pancreatitis; Rats; Rats, Wistar; Resveratrol; Sincalide; Stilbenes; Superoxide Dismutase; Time Factors; Triglycerides; Tumor Necrosis Factor-alpha | 2006 |
The effect of resveratrol in experimental cataract model formed by sodium selenite.
Topics: Animals; Antioxidants; Cataract; Disease Models, Animal; Glutathione; Lens, Crystalline; Lipid Peroxidation; Malondialdehyde; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium Selenite; Stilbenes | 2006 |
Unlocking the secrets of longevity genes.
Topics: Aging; Animals; Diet; DNA, Ribosomal; Energy Intake; Energy Metabolism; Humans; Insulin; Insulin-Like Growth Factor I; Longevity; Mutation; NAD; Repetitive Sequences, Nucleic Acid; Resveratrol; Saccharomyces cerevisiae; Sirtuins; Stilbenes; Stress, Physiological | 2006 |
Suppression of human monocyte tissue factor induction by red wine phenolics and synthetic derivatives of resveratrol.
Topics: Cells, Cultured; Dietary Supplements; Drug Synergism; Gene Expression Regulation; Humans; Monocytes; Phenol; Quercetin; Resveratrol; Stilbenes; Structure-Activity Relationship; Thromboplastin; Wine | 2007 |
Nepalensinols D-G, new resveratrol oligomers from Kobresia nepalensis (Cyperaceae) as potent inhibitors of DNA topoisomerase II.
Topics: Cyperaceae; Enzyme Inhibitors; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenols; Plant Stems; Resveratrol; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Stilbenes; Topoisomerase II Inhibitors | 2006 |
Resveratrol oligomers and their O-glucosides from Cotylelobium lanceolatum.
Topics: Ericales; Glucosides; Isomerism; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Resveratrol; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Stilbenes; Structure-Activity Relationship | 2006 |
Apoptosis of lymphocytes in allograft in a rat liver transplantation model induced by resveratrol.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Graft Rejection; Immunosuppressive Agents; Liver Transplantation; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Rats, Wistar; Resveratrol; Stilbenes; T-Lymphocytes; Transplantation, Homologous | 2006 |
Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 6; Caspases; Cell Line, Tumor; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Lamin Type A; Proteomics; Resveratrol; Signal Transduction; Stilbenes; Transgenes; Tumor Suppressor Protein p53 | 2006 |
Resveratrol prevents CsA inhibition of proliferation and osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells through an ER/NO/cGMP pathway.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Female; Mesenchymal Stem Cells; Mice; Nitric Oxide; Osteoblasts; Receptors, Estrogen; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Potentiation of a survival signal in the ischemic heart by resveratrol through p38 mitogen-activated protein kinase/mitogen- and stress-activated protein kinase 1/cAMP response element-binding protein signaling.
Topics: Animals; Cardiotonic Agents; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Ischemia; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Resveratrol, a red wine constituent polyphenol, protects gastric tissue against the oxidative stress in cholestatic rats.
Topics: Animals; Antioxidants; Bile Ducts; Cholestasis; Gastric Mucosa; Glutathione; Ligation; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Resveratrol; Stilbenes; Stomach | 2006 |
[Preventive effect of trans-resveratrol on hypertension-induced cardiac hypertrophy in partially nephrectomized rats].
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Endothelin-1; Hypertension; Male; Myocardium; Nephrectomy; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Protective effect of resveratrol, a polyphenolic phytoalexin on glycerol-induced acute renal failure in rat kidney.
Topics: Acute Kidney Injury; Animals; Enzyme Inhibitors; Glycerol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Female; Gene Expression; Humans; Male; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Stilbenes | 2006 |
Protective effects of resveratrol on spleen and ileum in rats subjected to ischemia-reperfusion.
Topics: Animals; Disease Models, Animal; Glutathione; Ileum; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Spleen; Stilbenes; Vasodilator Agents | 2006 |
Bax and Bak are the critical complementary effectors of colorectal cancer cell apoptosis by chemopreventive resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Colorectal Neoplasms; Humans; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Biosynthesis of plant-specific stilbene polyketides in metabolically engineered Escherichia coli.
Topics: Acyltransferases; Arabidopsis; Arabidopsis Proteins; Arachis; Biotransformation; Caffeic Acids; Cloning, Molecular; Coenzyme A Ligases; Coumaric Acids; Escherichia coli; Genetic Engineering; Kinetics; Resveratrol; Stilbenes | 2006 |
Resveratrol and propolis extract: an insight into the morphological and molecular changes induced in DU145 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Therapy, Combination; Flow Cytometry; Humans; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Propolis; Prostatic Neoplasms; Resveratrol; Stilbenes | 2006 |
Effects of long-term treatment with resveratrol and subcutaneous and oral estradiol administration on the pituitary-thyroid-axis.
Topics: Administration, Oral; Animal Feed; Animals; Arachis; Cardiotonic Agents; Cell Culture Techniques; Estradiol; Female; Injections, Subcutaneous; Neurosecretory Systems; Ovariectomy; Pituitary Gland; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thyroid Gland; Thyrotropin, beta Subunit; Vasodilator Agents; Wine | 2006 |
[Simultaneous determination of resveratrol, emodin, chrysophanol, physcion, in root of Polygonam cuspidatum and its extract by HPLC].
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Plant Roots; Plants, Medicinal; Quality Control; Resveratrol; Stilbenes | 2006 |
[Study on the preparation of resveratrol chitosan nanoparticles with free amino groups on the surface].
Topics: Chitosan; Drug Compounding; Drug Delivery Systems; Nanostructures; Particle Size; Resveratrol; Stilbenes | 2006 |
Specific plasma membrane binding sites for polyphenols, including resveratrol, in the rat brain.
Topics: Animals; Binding Sites; Brain; Cell Membrane; Dose-Response Relationship, Drug; Flavonoids; Male; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2006 |
Resveratrol and its glycon piceid are stable polyphenols.
Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Drug Stability; Flavonoids; Fruit; Glucosides; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Time Factors; Vitis | 2006 |
Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism.
Topics: Antimony; Antineoplastic Agents; Cell Proliferation; HL-60 Cells; Humans; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2006 |
Relative effects of phenolic constituents from Yucca schidigera Roezl. bark on Kaposi's sarcoma cell proliferation, migration, and PAF synthesis.
Topics: Antineoplastic Agents; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Bark; Plant Extracts; Platelet Activating Factor; Resveratrol; Sarcoma, Kaposi; Spiro Compounds; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Yucca | 2006 |
Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone.
Topics: Antioxidants; Aryl Hydrocarbon Receptor Nuclear Translocator; Caco-2 Cells; Cell Line; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Hydroquinones; Mutation; Oxazines; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Stilbenes; Transfection | 2006 |
Protection of peroxynitrite-induced DNA damage by dietary antioxidants.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Catechin; Deoxyguanosine; Diet; DNA; DNA Damage; Free Radical Scavengers; Humans; Molsidomine; Peroxynitrous Acid; Resveratrol; Stilbenes; Triterpenes; U937 Cells; Ursolic Acid | 2006 |
Glucuronidation of trans-resveratrol by human liver and intestinal microsomes and UGT isoforms.
Topics: Animals; Dose-Response Relationship, Drug; Glucuronides; Glucuronosyltransferase; Humans; Insecta; Isoenzymes; Microsomes, Liver; Resveratrol; Stilbenes; UDP-Glucuronosyltransferase 1A9 | 2006 |
Neuroprotective effects of resveratrol on cerebral ischemia-induced neuron loss mediated by free radical scavenging and cerebral blood flow elevation.
Topics: Animals; Blood Pressure; Brain Ischemia; Free Radical Scavengers; Heart Rate; Hippocampus; Male; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2006 |
The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cancer cells.
Topics: Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Primers; Humans; Kinetics; Promoter Regions, Genetic; Resveratrol; RNA, Messenger; Stilbenes; Testosterone; Wine | 2006 |
Resveratrol suppresses tumor necrosis factor-alpha-induced fractalkine expression in endothelial cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Adhesion; Cell Line; Cells, Cultured; Chemokine CX3CL1; Chemokines, CX3C; CX3C Chemokine Receptor 1; Ectodysplasins; Endothelial Cells; Gene Expression; Humans; Intestinal Mucosa; Intestines; Kidney; Macrophages; Membrane Proteins; Microvilli; Monocytes; Myocardium; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors | 2006 |
Effects of long-term treatment with resveratrol and subcutaneous and oral estradiol administration on pituitary function in rats.
Topics: Administration, Oral; Animals; Drug Administration Schedule; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Glycoprotein Hormones, alpha Subunit; Luteinizing Hormone, beta Subunit; Ovariectomy; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, LHRH; Resveratrol; RNA, Messenger; Stilbenes; Time Factors; Transcription, Genetic | 2006 |
Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 2; Caspase 3; Caspase 8; Caspase 9; Caspases; Colonic Neoplasms; Cytochromes c; Cytosol; Endodeoxyribonucleases; Fibroblasts; Green Fluorescent Proteins; HCT116 Cells; Humans; Mice; Mitochondria; Poly(ADP-ribose) Polymerases; Protein Conformation; Resveratrol; Stilbenes | 2006 |
Potent inhibitory effects of resveratrol derivatives on progression of prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Humans; Male; Prostatic Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2006 |
Strategies for comparing gene expression profiles from different microarray platforms: application to a case-control experiment.
Topics: Breast Neoplasms; Case-Control Studies; Computational Biology; DNA, Complementary; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Meta-Analysis as Topic; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes | 2006 |
[Resveratrol induces HepG2 cell apoptosis by depolarizing mitochondrial membrane].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Membrane Potentials; Mitochondrial Membranes; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits insulin responses in a SirT1-independent pathway.
Topics: Animals; Cells, Cultured; Depression, Chemical; Fatty Acid Synthases; Glucokinase; Glucose-6-Phosphatase; GRB2 Adaptor Protein; Hepatocytes; Histone Deacetylase Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Protein Subunits; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage.
Topics: Animals; Apoptosis Inducing Factor; Cell Death; Cell Line; DNA Damage; Enzyme Inhibitors; Gene Expression Regulation; Humans; Mice; Models, Biological; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity.
Topics: Animals; Blood Platelets; Brain; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Isomerism; Male; Metabolic Clearance Rate; Monoamine Oxidase; Norepinephrine; Rats; Rats, Sprague-Dawley; Resveratrol; Serotonin; Stilbenes; Structure-Activity Relationship; Synaptosomes | 2006 |
Effect of resveratrol on nitrate tolerance in isolated human internal mammary artery.
Topics: Catalase; Drug Tolerance; Endothelium, Vascular; Humans; Hydrogen Peroxide; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; NAD; Nitroglycerin; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Vasodilation | 2006 |
Effects of resveratrol on mast cell degranulation and tyrosine phosphorylation of the signaling components of the IgE receptor.
Topics: Animals; Cell Degranulation; Cell Line, Tumor; Mast Cells; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Resveratrol; Stilbenes; Veratrum | 2006 |
NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration.
Topics: Animals; Axons; Mice; Mice, Inbred C57BL; Mice, Transgenic; NAD; Nerve Tissue Proteins; Nicotinamide-Nucleotide Adenylyltransferase; Point Mutation; Resveratrol; Sciatic Neuropathy; Stilbenes; Wallerian Degeneration | 2007 |
Use of resveratrol to improve the effectiveness of cisplatin and doxorubicin: study in human gynecologic cancer cell lines and in rodent heart.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bradycardia; Cardiotonic Agents; Cell Division; Cell Survival; Cells, Cultured; Cisplatin; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Female; Humans; Long QT Syndrome; Mice; Myocytes, Cardiac; Ovarian Neoplasms; Rats; Resveratrol; Stilbenes; Uterine Neoplasms | 2006 |
Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Lewis Lung; Caspase 3; Caspase 9; Caspases; Cell Proliferation; Female; Fibroblast Growth Factor 2; Mice; Mice, Inbred C57BL; Proliferating Cell Nuclear Antigen; Resveratrol; Stilbenes | 2006 |
Effects of neonatal resveratrol exposure on adult male and female reproductive physiology and behavior.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Female; Male; Ovary; Phytoestrogens; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Reproduction; Resveratrol; Seminal Vesicles; Sexual Behavior, Animal; Stilbenes; Testis; Uterus | 2006 |
Analysis of the resveratrol-binding protein using phage-displayed random peptide library.
Topics: Breast; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Humans; Mammary Glands, Human; Peptide Library; Peptides; Resveratrol; Stilbenes | 2006 |
The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery.
Topics: 4-Aminopyridine; Anti-Arrhythmia Agents; Charybdotoxin; Coronary Artery Bypass; Coronary Disease; Glyburide; Humans; Male; Mammary Arteries; Middle Aged; Muscle Relaxation; Muscle, Smooth, Vascular; Neurotoxins; Potassium Channel Blockers; Potassium Channels; Resveratrol; Scorpion Venoms; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents; Wine | 2006 |
Differential modulation of ovine fetal ACTH secretion by PGHS-1 and PGHS-2.
Topics: Adrenocorticotropic Hormone; Animals; Blood Gas Analysis; Blood Pressure; Brain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fetus; Heart Rate; Hydrocortisone; Hypotension; Hypothalamo-Hypophyseal System; Pituitary-Adrenal System; Pregnancy; Pregnancy, Animal; Resveratrol; Sheep; Stilbenes; Sulfonamides | 2006 |
Effect of natural analogues of trans-resveratrol on cytochromes P4501A2 and 2E1 catalytic activities.
Topics: Animals; Catalytic Domain; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Inhibitory Concentration 50; Kinetics; Liver; Mice; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in beta-amyloid-treated C6 glioma cells.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Glioma; Neuroglia; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type II; Protein Transport; Rats; Resveratrol; Stilbenes; Transcriptional Activation | 2006 |
Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fusion Proteins, bcr-abl; G1 Phase; Humans; Leukemia, Promyelocytic, Acute; Resting Phase, Cell Cycle; Resveratrol; Stilbenes; Structure-Activity Relationship; Terphenyl Compounds | 2006 |
Resveratrol and the pharmacology of aging: a new vertebrate model to validate an old molecule.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caenorhabditis elegans; Dose-Response Relationship, Drug; Drosophila; Killifishes; Longevity; Models, Animal; Resveratrol; Stilbenes | 2006 |
Acid-promoted reaction of the stilbene antioxidant resveratrol with nitrite ions: mild phenolic oxidation at the 4'-hydroxystiryl sector triggering nitration, dimerization, and aldehyde-forming routes.
Topics: Acids; Aldehydes; Antioxidants; Dimerization; Ions; Molecular Structure; Nitrites; Oxidation-Reduction; Resveratrol; Stilbenes | 2006 |
Structure-activity relationship studies of resveratrol and its analogues by the reaction kinetics of low density lipoprotein peroxidation.
Topics: alpha-Tocopherol; Antioxidants; Copper; Humans; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors | 2006 |
In vitro effects of genistein and resveratrol on the production of interferon-gamma (IFNgamma) and interleukin-10 (IL-10) by stimulated murine splenocytes.
Topics: Animals; Cell Survival; Genistein; In Vitro Techniques; Interferon-gamma; Interleukin-10; Male; Mice; Mice, Inbred C57BL; Phytoestrogens; Phytotherapy; Plants, Medicinal; Resveratrol; Spleen; Stilbenes | 2006 |
c-Myc downregulation: a critical molecular event in resveratrol-induced cell cycle arrest and apoptosis of human medulloblastoma cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Down-Regulation; Flow Cytometry; Fluorescent Antibody Technique; Genes, myc; Humans; Immunohistochemistry; Medulloblastoma; Neoplasm Proteins; Oligonucleotides, Antisense; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; S Phase; Stilbenes; Transfection | 2006 |
Apoptosis in a tissue-like culture model of human colorectal adenoma cells.
Topics: Adenoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Culture Techniques; Collagen; Colorectal Neoplasms; Drug Evaluation, Preclinical; Models, Biological; Quercetin; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2006 |
Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3'-kinase/Akt pathway and Bcl-2 family proteins.
Topics: Androgens; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Microscopy, Fluorescence; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Catalase; Diet; Glutathione; Intestinal Neoplasms; Lipid Peroxidation; Male; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2006 |
Comparison of ozone and UV-C treatments on the postharvest stilbenoid monomer, dimer, and trimer induction in var. 'Superior' white table grapes.
Topics: Fruit; Ozone; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2006 |
Regulation of proliferation and gene expression in cultured human aortic smooth muscle cells by resveratrol and standardized grape extracts.
Topics: Aorta; Apoptosis Inducing Factor; Cardiotonic Agents; Cell Proliferation; Cells, Cultured; Chromatography, Affinity; Electron Transport Complex IV; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heat-Shock Proteins; Humans; Muscle Relaxation; Muscle, Smooth, Vascular; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide Synthase Type III; Plant Extracts; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Vitis; Wine | 2006 |
Resveratrol inhibits proliferation of human epidermoid carcinoma A431 cells by modulating MEK1 and AP-1 signalling pathways.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dimerization; DNA-Binding Proteins; Dose-Response Relationship, Drug; Flavonoids; Gene Expression; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-jun; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Transcription Factor AP-1 | 2006 |
Cardioprotective effect of resvaratrol pretreatment on myocardial ischemia-reperfusion induced injury in rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Free Radical Scavengers; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Up-Regulation | 2006 |
Effects of resveratrol on endothelial progenitor cells and their contributions to reendothelialization in intima-injured rats.
Topics: Angiogenesis Inhibitors; Animals; Aorta, Abdominal; Aorta, Thoracic; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Male; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stem Cells; Stilbenes; Tunica Intima; Up-Regulation | 2006 |
Gerontology: eat your cake and have it.
Topics: Aging; Animals; Caloric Restriction; Cellular Senescence; Drug Evaluation, Preclinical; Drug Industry; Energy Intake; Energy Metabolism; Geriatrics; Ghrelin; Humans; Insulin; Longevity; Metformin; Peptide Hormones; Randomized Controlled Trials as Topic; Reproduction; Resveratrol; Sirtuins; Stilbenes; Time Factors | 2006 |
Possible inhibition of group I intron RNA by resveratrol and genistein.
Topics: Candida albicans; Genistein; Introns; Resveratrol; RNA; Stilbenes | 2006 |
Resveratrol enhances UVA-induced DNA damage in HaCaT human keratinocytes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; Deoxyguanosine; DNA; DNA Damage; Humans; Keratinocytes; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Structure-Activity Relationship; Ultraviolet Rays | 2005 |
Integrin alphaVbeta3 contains a receptor site for resveratrol.
Topics: Apoptosis; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Integrin alphaVbeta3; Integrin beta3; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2006 |
Transgenic peas (Pisum sativum) expressing polygalacturonase inhibiting protein from raspberry (Rubus idaeus) and stilbene synthase from grape (Vitis vinifera).
Topics: Acyltransferases; Fungal Proteins; Gene Expression Regulation, Plant; Gene Transfer Techniques; Pisum sativum; Plant Proteins; Plants, Genetically Modified; Polygalacturonase; Resveratrol; Rhizobium; Rosaceae; Stilbenes; Vitis | 2006 |
Comparative study of natural antioxidants - curcumin, resveratrol and melatonin - in cadmium-induced oxidative damage in mice.
Topics: Animals; Antioxidants; Cadmium; Catalase; Curcumin; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Melatonin; Mice; Mice, Inbred Strains; Oxidative Stress; Resveratrol; Stilbenes | 2006 |
Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells.
Topics: Adipocytes; Animals; Calcification, Physiologic; Cell Differentiation; Cell Line; Enzyme Inhibitors; Mesenchymal Stem Cells; Mice; Niacinamide; Osteoblasts; Osteogenesis; PPAR gamma; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2006 |
Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: Novel cellular mechanisms involving the ERKs/p53 cascade.
Topics: Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Humans; Osteosarcoma; Poly(ADP-ribose) Polymerases; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2006 |
Modulatory effects of resveratrol, citroflavan-3-ol, and plant-derived extracts on oxidative stress in U937 cells.
Topics: Antioxidants; Arctostaphylos; Cell Survival; DNA Damage; Echinacea; Flavonoids; Humans; Hydrogen Peroxide; Olea; Oxidative Stress; Phenols; Plant Extracts; Plant Leaves; Polyphenols; Resveratrol; Seeds; Stilbenes; tert-Butylhydroperoxide; U937 Cells; Vitis | 2006 |
Potential pro-inflammatory action of resveratrol in vascular smooth muscle cells from normal and diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Genistein; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Resveratrol; Stilbenes; Tissue Culture Techniques | 2006 |
[Contents comparison of resveratrol and polydatin in the wild Polygonum cuspidatum plant and its tissue cultures].
Topics: Biomass; Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Plant Leaves; Plant Roots; Plant Stems; Plants, Medicinal; Reproducibility of Results; Resveratrol; Rhizome; Seedlings; Stilbenes; Tissue Culture Techniques | 2006 |
Resveratrol induces apoptotic cell death in rat H4IIE hepatoma cells but necrosis in C6 glioma cells.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Line; Cell Survival; Comet Assay; DNA Damage; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioma; Necrosis; Rats; Resveratrol; Stilbenes | 2006 |
Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism.
Topics: Acetyltransferases; Antineoplastic Agents, Phytogenic; Biogenic Polyamines; Caco-2 Cells; Cell Growth Processes; Colonic Neoplasms; Enzyme Activation; HCT116 Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Pyridines; Resveratrol; Stilbenes; Transcription, Genetic; Transfection | 2006 |
Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway.
Topics: Animals; Animals, Newborn; Blotting, Western; Cell Count; Cell Death; Enzyme Inhibitors; Glucose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Hypoxia, Brain; Male; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Oncogene Protein v-akt; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes | 2006 |
[Resveratrol promotes Ca2+-induced Ca2+ release from rat liver cell mitochondria mediated by Ca2+].
Topics: Animals; Calcium; Cells, Cultured; Female; Hepatocytes; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2006 |
[Effects of resveratrol on growth inhibition and gap-junctional intercellular communication of HepG2 cells].
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Communication; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gap Junctions; Humans; Liver Neoplasms; Resveratrol; S Phase; Stilbenes | 2006 |
Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Survival; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; K562 Cells; Leukemia; Mice; Oxidants; Protein-Tyrosine Kinases; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2006 |
Distribution of [3H]trans-resveratrol in rat tissues following oral administration.
Topics: Absorption; Administration, Oral; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Glucuronides; Kidney; Liver; Lung; Male; Myocardium; Rats; Rats, Sprague-Dawley; Resveratrol; Spleen; Stilbenes; Tissue Distribution; Tritium | 2006 |
Dietary supplementation of resveratrol suppresses colonic tumour incidence in 1,2-dimethylhydrazine-treated rats by modulating biotransforming enzymes and aberrant crypt foci development.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents, Phytogenic; Bacteria; Carcinogens; Colon; Colonic Neoplasms; Dietary Supplements; Disease Models, Animal; Feces; Glycoside Hydrolases; Intestinal Mucosa; Male; Nitroreductases; Polysaccharide-Lyases; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfatases | 2006 |
Resveratrol, a polyphenolic phytoalexin attenuates thermal hyperalgesia and cold allodynia in STZ-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Cold Temperature; Diabetes Mellitus, Experimental; Hot Temperature; Hyperalgesia; Immersion; Male; Phytoalexins; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes | 2006 |
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Apigenin; Atherosclerosis; Benzopyrans; Carcinoma, Hepatocellular; Cell Line, Tumor; Diabetes Mellitus, Experimental; Enzyme Activation; Flavonoids; Glucose; Humans; Hypolipidemic Agents; Lipid Metabolism; Lipids; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Multienzyme Complexes; Phenols; Phosphorylation; Polyphenols; Protein Serine-Threonine Kinases; Receptors, LDL; Resveratrol; Stilbenes | 2006 |
Inhibition of excitatory synaptic transmission by trans-resveratrol in rat hippocampus.
Topics: Animals; Antioxidants; Cell Membrane; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resveratrol; Stilbenes; Synaptic Transmission | 2006 |
Resveratrol suppresses nuclear factor-kappaB in herpes simplex virus infected cells.
Topics: Animals; Antiviral Agents; Cell Nucleus; Chlorocebus aethiops; Cytoplasm; DNA, Viral; Electrophoretic Mobility Shift Assay; Herpesvirus 1, Human; Herpesvirus 2, Human; I-kappa B Proteins; Microscopy, Fluorescence; NF-kappa B; NF-KappaB Inhibitor alpha; Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Stilbenes; Transcription Factor RelA; Vero Cells; Virus Replication | 2006 |
Effect of resveratrol on NF-kappaB activity in rat peritoneal macrophages.
Topics: Animals; Antioxidants; Immunohistochemistry; Interleukin-1; Lipopolysaccharides; Macrophages, Peritoneal; Male; NF-kappa B; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
[Effects of light intensity on resveratrol and polydatin production in Rumex gmelini root].
Topics: Glucosides; Plant Roots; Resveratrol; Rumex; Seasons; Stilbenes; Sunlight; Time Factors | 2006 |
Production of resveratrol in recombinant microorganisms.
Topics: Acyltransferases; Biotechnology; Coenzyme A Ligases; Coumaric Acids; Escherichia coli; Nicotiana; Recombination, Genetic; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Vitis | 2006 |
Pharmacological evidence for the participation of NO-cyclic GMP-PKG-K+ channel pathway in the antiallodynic action of resveratrol.
Topics: Animals; Antioxidants; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Female; Glyburide; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides; Potassium; Rats; Rats, Wistar; Resveratrol; Spine; Stilbenes | 2006 |
Resveratrol inhibition of varicella-zoster virus replication in vitro.
Topics: Antiviral Agents; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Fibroblasts; Herpesvirus 3, Human; Humans; Immediate-Early Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Stilbenes; Trans-Activators; Viral Envelope Proteins; Viral Plaque Assay; Virus Attachment; Virus Inactivation; Virus Replication | 2006 |
Resveratrol regulates the expression of LXR-alpha in human macrophages.
Topics: Cell Line, Tumor; DNA-Binding Proteins; Gene Expression Regulation; Humans; Lipid Metabolism; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2006 |
Resveratrol increases glutamate uptake and glutamine synthetase activity in C6 glioma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Rats; Resveratrol; Stilbenes | 2006 |
Cell based screening of inhibitors of transthyretin aggregation.
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Lineage; Cell Survival; Diflunisal; Drug Evaluation, Preclinical; Humans; Methionine; Microfibrils; Neurons; Prealbumin; Resveratrol; Stilbenes; Valine | 2006 |
Resveratrol, a natural phenolic compound may reduce carbonylation proteins induced by peroxynitrite in blood platelets.
Topics: Antioxidants; Blood Platelets; Carbon; Colorimetry; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Lipid Peroxidation; Oxygen; Peroxynitrous Acid; Phenol; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2006 |
Effect of resveratrol on proliferation and telomerase activity of human colon cancer cells in vitro.
Topics: Angiogenesis Inhibitors; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; DNA-Binding Proteins; Humans; Resveratrol; Stilbenes; Telomerase | 2006 |
A specific method for measurement of equine active myeloperoxidase in biological samples and in in vitro tests.
Topics: Animals; Body Fluids; Curcumin; Enzyme-Linked Immunosorbent Assay; Horse Diseases; Horses; Neutrophils; Peroxidase; Resveratrol; Sensitivity and Specificity; Stilbenes; Temperature; Time Factors | 2006 |
Neuroprotection by resveratrol against traumatic brain injury in rats.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Xanthine Oxidase | 2007 |
The beneficial effect of resveratrol on rat bladder contractility and oxidant damage following ischemia/reperfusion.
Topics: Animals; Female; Glutathione; In Vitro Techniques; Lipid Peroxidation; Male; Muscle Contraction; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Urinary Bladder | 2006 |
[Quantitative determination of the (E) - and (Z) -diastereomers of resveratrol and resveratrol glucoside in the roots of Polygonum cuspidatum by HPLC and elementary study on their fluorescence].
Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Fluorescence; Glucosides; Plant Roots; Plants, Medicinal; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes | 2006 |
Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Nucleus; Cyclooxygenase 2; E1A-Associated p300 Protein; Female; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Resveratrol; Serine; Signal Transduction; Stilbenes; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2006 |
Mitochondria as the primary target of resveratrol-induced apoptosis in human retinoblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Caspases; Cell Cycle; Cell Proliferation; Cytochromes c; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Membrane Potentials; Mitochondria; Quinone Reductases; Resveratrol; Retinal Neoplasms; Retinoblastoma; Ribonucleotide Reductases; RNA, Messenger; Stilbenes; Time Factors; Tumor Cells, Cultured | 2006 |
Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Cell Survival; Glutathione; Huntington Disease; Injections, Intraperitoneal; Lipid Peroxidation; Male; Motor Activity; Neurons; Neuroprotective Agents; Neurotoxins; Nitro Compounds; Propionates; Rats; Rats, Wistar; Resveratrol; Retention, Psychology; Stereotyped Behavior; Stilbenes; Succinate Dehydrogenase | 2006 |
Induction of quinone reductase NQO1 by resveratrol in human K562 cells involves the antioxidant response element ARE and is accompanied by nuclear translocation of transcription factor Nrf2.
Topics: Antioxidants; Base Sequence; Cell Nucleus; DNA Primers; Electrophoretic Mobility Shift Assay; Humans; K562 Cells; Microscopy, Fluorescence; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Protein Transport; Resveratrol; Stilbenes; Transcription, Genetic | 2006 |
Electrochemical sensing DNA damage with nano-titanium dioxide and repair with a medicinal herb species resveratrol.
Topics: Antioxidants; Biosensing Techniques; Chromatography, High Pressure Liquid; DNA Damage; DNA Repair; Drugs, Chinese Herbal; Electrochemistry; Molecular Structure; Nanotechnology; Reactive Oxygen Species; Resveratrol; Stilbenes; Surface Properties; Titanium | 2007 |
[Inhibitory effect of resveratrol on the proliferation of synoviocytes in rheumatoid arthritis and its mechanism in vitro].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Depression, Chemical; Female; Humans; Male; Middle Aged; Resveratrol; Stilbenes; Synovial Membrane | 2006 |
[Effect of resveratrol on the cognitive ability of Alzheimeros mice].
Topics: Alzheimer Disease; Animals; Antioxidants; Cognition; Female; Galactose; Mice; Ovariectomy; Random Allocation; Resveratrol; Stilbenes | 2006 |
Increased transport of resveratrol across monolayers of the human intestinal Caco-2 cells is mediated by inhibition and saturation of metabolites.
Topics: Algorithms; Animals; Anticarcinogenic Agents; Biological Transport, Active; Biotransformation; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Glucuronides; Humans; Liver; Male; Rats; Rats, Wistar; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Sulfates | 2006 |
Resveratrol inhibits aggregation of platelets from high-risk cardiac patients with aspirin resistance.
Topics: Adult; Aged; Aspirin; Drug Resistance; Female; Heart Diseases; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2006 |
Estradiol and resveratrol stimulating effect on osteocalcin, but not osteonectin and collagen-1alpha gene expression in primary culture of rat calvarial osteoblast-like cells.
Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Benzophenones; Bridged Bicyclo Compounds; Cell Proliferation; Cells, Cultured; Collagen Type I; Dose-Response Relationship, Drug; Estradiol; Gene Expression; Genistein; Linuron; Osteoblasts; Osteocalcin; Osteonectin; Phenols; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Silymarin; Skull; Stilbenes | 2006 |
Oncogenicity evaluation of resveratrol in p53(+/-) (p53 knockout) mice.
Topics: Administration, Oral; Anemia; Aniline Compounds; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Chemoprevention; Cholesterol; Dose-Response Relationship, Drug; Female; Hydronephrosis; Kidney; Liver; Longevity; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Urinary Bladder | 2007 |
Detection and quantitation of resveratrol in tomato fruit (Lycopersicon esculentum Mill.).
Topics: Anticarcinogenic Agents; Antioxidants; Fruit; Resveratrol; Solanum lycopersicum; Stilbenes; Time Factors; Vitis | 2006 |
Resveratrol improves ischemia/reperfusion-induced oxidative renal injury in rats.
Topics: Acridines; Animals; Antioxidants; Blood Urea Nitrogen; Creatine; Glutathione; Kidney Diseases; L-Lactate Dehydrogenase; Luminol; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2006 |
Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition.
Topics: Antioxidants; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Cell Adhesion; Cells, Cultured; Coronary Vessels; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Hydrogen Peroxide; Intercellular Adhesion Molecule-1; Interleukin-6; Monocytes; NF-kappa B; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Pyrrolidines; Resveratrol; Stilbenes; Thiocarbamates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2006 |
Inhibition of phosphatidylinositol 3-kinase-mediated glucose metabolism coincides with resveratrol-induced cell cycle arrest in human diffuse large B-cell lymphomas.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Chromones; Enzyme Inhibitors; Glucose; Glycolysis; Humans; Lymphoma, Large B-Cell, Diffuse; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Resveratrol; Stilbenes | 2006 |
[Research on resveratrol's mechanism of immunity in anti-aging].
Topics: Aging; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Female; Interleukin-6; Interleukin-8; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Plants, Medicinal; Resveratrol; Stilbenes; Superoxide Dismutase | 2006 |
Cytotoxic and biochemical effects of 3,3',4,4',5,5'-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cytarabine; Deoxyribonucleotides; Drug Evaluation, Preclinical; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; NF-kappa B; Pyrogallol; Resveratrol; Ribonucleotide Reductases; Ribonucleotides; Stilbenes; Tumor Necrosis Factor-alpha; Wine | 2006 |
[Effect of resveratrol on lipopolysaccharide-induced activation of rat peritoneal macrophages].
Topics: Animals; Cytokines; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Male; NF-kappa B; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2006 |
Resveratrol is rapidly metabolized in athymic (nu/nu) mice and does not inhibit human melanoma xenograft tumor growth.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Diet; Drug Implants; Humans; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Oxidation-Reduction; Resveratrol; Stilbenes; Transplantation, Heterologous | 2006 |
Resveratrol impairs the formation of MDA-MB-231 multicellular tumor spheroids concomitant with ceramide accumulation.
Topics: Breast Neoplasms; Cell Aggregation; Ceramides; Female; Humans; Resveratrol; Spheroids, Cellular; Stilbenes; Tumor Cells, Cultured | 2007 |
Resveratrol or higher arterial blood pressure protects the spinal cord from ischemia-reperfusion injury?
Topics: Animals; Blood Pressure; Disease Models, Animal; Ischemic Preconditioning; Rabbits; Reperfusion Injury; Resveratrol; Spinal Cord Ischemia; Stilbenes; Swine; Vasodilator Agents | 2006 |
SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity.
Topics: Acetylation; Apoptosis; bcl-2-Associated X Protein; Cell Transformation, Neoplastic; DNA-Binding Proteins; Down-Regulation; Enzyme Inhibitors; Gamma Rays; Genes, Reporter; HeLa Cells; Humans; Luciferases; Niacinamide; Nuclear Proteins; Oligonucleotides, Antisense; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-mdm2; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic; Transfection; Tumor Protein p73; Tumor Suppressor Proteins | 2007 |
Synthesis and cytotoxic evaluation of a series of resveratrol derivatives modified in C2 position.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; KB Cells; Resveratrol; Stilbenes; Structure-Activity Relationship | 2007 |
Inhibition of swarming and virulence factor expression in Proteus mirabilis by resveratrol.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; Genetic Complementation Test; Humans; Movement; Mutation; Proteus mirabilis; Resveratrol; Stilbenes; Virulence Factors | 2006 |
Resveratrol engages selective apoptotic signals in gastric adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Line, Tumor; Electron Transport Complex IV; Fas-Associated Death Domain Protein; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Stomach Neoplasms; Survivin; Tumor Suppressor Protein p53 | 2006 |
[Resveratrol inhibits expression of EMMPRIN from macrophages].
Topics: Anilides; Antineoplastic Agents, Phytogenic; Basigin; Blotting, Western; Breast Neoplasms; Cell Differentiation; Cell Line; Cell Line, Tumor; Coculture Techniques; Dose-Response Relationship, Drug; Female; Humans; Luciferases; Macrophages; Matrix Metalloproteinase 9; Monocytes; Pioglitazone; PPAR gamma; Recombinant Fusion Proteins; Resveratrol; Stilbenes; Thiazolidinediones; U937 Cells | 2006 |
Effects of resveratrol and methylprednisolone on biochemical, neurobehavioral and histopathological recovery after experimental spinal cord injury.
Topics: Animals; Glutathione; Male; Malondialdehyde; Methylprednisolone; Motor Activity; Neuroprotective Agents; Nitric Oxide; Rats; Rats, Wistar; Resveratrol; Spinal Cord; Spinal Cord Injuries; Stilbenes; Xanthine Oxidase | 2006 |
Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells.
Topics: beta-Glucosidase; Biological Transport; Caco-2 Cells; Chromatography, High Pressure Liquid; Epithelial Cells; Glucosides; Humans; Intestinal Absorption; Intestine, Small; Lactase-Phlorizin Hydrolase; Membrane Glycoproteins; Resveratrol; Stilbenes; Wine | 2006 |
Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Flavanones; Flavones; Flavonoids; Humans; Kaempferols; Liver Transplantation; Luteolin; Receptors, Aryl Hydrocarbon; Resveratrol; Smoking; Stilbenes | 2007 |
Anti-mitotic properties of resveratrol analog (Z)-3,5,4'-trimethoxystilbene.
Topics: Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Mitosis; Resveratrol; Stereoisomerism; Stilbenes; Tubulin; Tubulin Modulators | 2006 |
Diverse resveratrol sensitization to apoptosis induced by anticancer drugs in sensitive and resistant leukemia cells.
Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Busulfan; Cell Cycle; Cell Line, Tumor; Cycloheximide; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Gemcitabine; Humans; Leukemia; Paclitaxel; Resveratrol; Stilbenes | 2006 |
Cardioprotective effect of resveratrol via HO-1 expression involves p38 map kinase and PI-3-kinase signaling, but does not involve NFkappaB.
Topics: Animals; Apoptosis; Cardiotonic Agents; Heart; Heme Oxygenase-1; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Metalloporphyrins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protoporphyrins; Rats; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Using unnatural protein fusions to engineer resveratrol biosynthesis in yeast and Mammalian cells.
Topics: Acyltransferases; Ammonia-Lyases; Arabidopsis Proteins; Cell Line; Cloning, Molecular; Coenzyme A Ligases; Humans; Kidney; Protein Engineering; Recombinant Fusion Proteins; Resveratrol; Rhodobacter sphaeroides; Saccharomyces cerevisiae; Stilbenes | 2006 |
Plant phenolics inhibit neutrophil elastase.
Topics: Catechin; Genistein; Humans; Hydrolyzable Tannins; Leukocyte Elastase; Phenols; Phenylethyl Alcohol; Plant Extracts; Proteinase Inhibitory Proteins, Secretory; Resveratrol; Stilbenes | 2006 |
Resveratrol inhibits cell growth and induces apoptosis of rat C6 glioma cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Glioma; In Situ Nick-End Labeling; Mice; Rats; Resveratrol; Stilbenes | 2007 |
High content of resveratrol in lettuce transformed with a stilbene synthase gene of Parthenocissus henryana.
Topics: Acyltransferases; Apoptosis; Blotting, Northern; HeLa Cells; Humans; Lactuca; Plants, Genetically Modified; Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Transfection; Vitaceae | 2006 |
The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Breast Neoplasms; Cell Line; Cell Line, Tumor; Dogs; Female; Folic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Methotrexate; Mitoxantrone; Neoplasm Proteins; Rabbits; Resveratrol; Stilbenes; Topotecan | 2007 |
Resveratrol alleviates bleomycin-induced lung injury in rats.
Topics: Administration, Oral; Animals; Antibiotics, Antineoplastic; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Glutathione; Lipid Peroxidation; Lung; Male; Malondialdehyde; Neutrophil Infiltration; Peroxidase; Pulmonary Fibrosis; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
[Effects of resveratrol on pig primary preadipocytes proliferation, differentiation and transcription expression of Sirt1 gene].
Topics: Adipocytes; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Resveratrol; RNA, Messenger; Sirtuin 1; Stem Cells; Stilbenes; Swine; Transcription, Genetic | 2006 |
Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway.
Topics: Aldehydes; Animals; Antioxidants; Brain Ischemia; Cells, Cultured; Flavonoids; Flavonols; Ion Channels; Male; Mitochondria; NAD; Naphthalenes; Neural Conduction; Neurotoxicity Syndromes; Neurotoxins; Niacinamide; Pyridines; Rats; Rats, Long-Evans; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Transcriptional Activation; Zinc | 2006 |
Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells.
Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endometrial Neoplasms; Female; HeLa Cells; Humans; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Uterine Neoplasms | 2006 |
[Comparison of resveratrol content of Smilax china from different habitats].
Topics: Altitude; China; Chromatography, High Pressure Liquid; Ecosystem; Plants, Medicinal; Quality Control; Reproducibility of Results; Resveratrol; Rhizome; Smilax; Stilbenes | 2006 |
[HPLC fingerprint of Rhizoma Polygoni Cuspidati].
Topics: Chromatography, High Pressure Liquid; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Quality Control; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical | 2006 |
Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Multiple Myeloma; Neoplasm Invasiveness; Plants, Medicinal; Polygonum; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.
Topics: Apoptosis; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; MAP Kinase Signaling System; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes; Transcription Factor CHOP; Transcription, Genetic | 2007 |
Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; G1 Phase; G2 Phase; Humans; Liver Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2006 |
Resveratrol binding to human serum albumin.
Topics: Angiogenesis Inhibitors; Binding Sites; Circular Dichroism; Humans; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Resveratrol; Serum Albumin; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2006 |
Resveratrol inhibits macrophage expression of EMMPRIN by activating PPARgamma.
Topics: Anilides; Anti-Inflammatory Agents, Non-Steroidal; Basigin; Cell Differentiation; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; I-kappa B Proteins; Macrophages; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Phosphorylation; Pioglitazone; PPAR gamma; Promoter Regions, Genetic; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Thiazolidinediones; Time Factors; Transfection; Tumor Necrosis Factor-alpha; U937 Cells | 2007 |
Protective effects of resveratrol in ischemia-reperfusion injury of skeletal muscle: A clinically relevant animal model for lower extremity ischemia.
Topics: Animals; Disease Models, Animal; Lower Extremity; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Treatment Outcome; Vasodilator Agents | 2006 |
[Studies on active substance of anticancer effect in Polygonum cuspidatum].
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Epithelial Cells; Fallopia japonica; Female; Humans; Liver Neoplasms; Plants, Medicinal; Rats; Resveratrol; Rhizome; Stilbenes | 2006 |
Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (acai).
Topics: Amino Acids; Arecaceae; Chromatography, High Pressure Liquid; Fatty Acids; Flavonoids; Freeze Drying; Fruit; Metals, Heavy; Molecular Structure; Resveratrol; Sterols; Stilbenes | 2006 |
Protective effect of resveratrol against oxidative damage of UVA irradiated HaCaT cells.
Topics: Cell Line, Transformed; DNA Damage; Glutathione Peroxidase; Humans; Keratinocytes; Malondialdehyde; Oxidative Stress; Radiation-Protective Agents; Resveratrol; Stilbenes; Superoxide Dismutase; Ultraviolet Rays | 2006 |
Resveratrol inhibits firefly luciferase.
Topics: Animals; Antioxidants; Cell Line; Genes, Reporter; Luciferases, Firefly; Mice; Resveratrol; Stilbenes | 2006 |
Syntheses of hydroxy substituted 2-phenyl-naphthalenes as inhibitors of tyrosinase.
Topics: Agaricales; Crystallography, X-Ray; Dealkylation; Enzyme Inhibitors; Hydroquinones; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Monophenol Monooxygenase; Morus; Naphthalenes; Pyrones; Resveratrol; Stilbenes | 2007 |
Resveratrol, an ingredient of wine, acts synergistically with Ara-C and tiazofurin in HL-60 human promyelocytic leukemia cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Free Radical Scavengers; Free Radicals; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Resveratrol; Ribavirin; Stilbenes | 2006 |
Expression of osteoblast marker genes in rat calvarial osteoblast-like cells, and effects of the endocrine disrupters diphenylolpropane, benzophenone-3, resveratrol and silymarin.
Topics: Animals; Benzhydryl Compounds; Benzophenones; Biomarkers; Cell Proliferation; Cells, Cultured; DNA, Complementary; Endocrine System; Gene Expression Regulation; Osteoblasts; Phenols; Rats; Rats, Wistar; Resveratrol; Silymarin; Skull; Stilbenes | 2006 |
Resveratrol inhibits insulin secretion from rat pancreatic islets.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phytoalexins; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Cytotoxic resveratrol oligomers from the tree bark of Dipterocarpus hasseltii.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Ericales; Mice; Phytotherapy; Plant Bark; Plant Extracts; Resveratrol; Stilbenes; Structure-Activity Relationship | 2006 |
Potassium channels-mediated vasorelaxation of rat aorta induced by resveratrol.
Topics: 4-Aminopyridine; Animals; Antioxidants; Aorta; Charybdotoxin; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Glyburide; In Vitro Techniques; Male; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Scorpion Venoms; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2006 |
Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Biological Transport; Caco-2 Cells; Catechin; Cell Line, Tumor; Chalcones; Flavonoids; Gene Expression; Humans; Hydroquinones; Indoles; Isothiocyanates; Maleates; Molecular Structure; Neoplasm Proteins; Plant Extracts; Quercetin; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Silymarin; Stilbenes; Sulfoxides; Thiocyanates; Transfection | 2007 |
Resveratrol affords protection against peroxynitrite-mediated endothelial cell death: A role for intracellular glutathione.
Topics: Animals; Apoptosis; Buthionine Sulfoximine; Cattle; Cell Shape; Cells, Cultured; Cytoprotection; Endothelial Cells; Glutathione; Peroxynitrous Acid; Resveratrol; Stilbenes | 2006 |
A votre santé: now in pill form?
Topics: Animals; Clinical Trials as Topic; Health; Humans; Mice; Obesity; Reproducibility of Results; Resveratrol; Sirtuins; Stilbenes | 2006 |
Determination of stoichiometric coefficients and apparent formation constants for beta-cyclodextrin complexes of trans-resveratrol using reversed-phase liquid chromatography.
Topics: beta-Cyclodextrins; Chromatography, High Pressure Liquid; Methanol; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Thermodynamics; Water | 2006 |
Resveratrol improves health and survival of mice on a high-calorie diet.
Topics: Acetylation; Adenylate Kinase; Animals; Energy Intake; Health; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Obesity; Oligonucleotide Array Sequence Analysis; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Stilbenes; Survival Rate; Trans-Activators; Transcription Factors | 2006 |
Medicine: grapes versus gluttony.
Topics: Animals; Caloric Restriction; Energy Intake; Health; Humans; Insulin Resistance; Longevity; Mice; Obesity; Resveratrol; Stilbenes | 2006 |
Resveratrol induces apoptosis in transformed follicular lymphoma OCI-LY8 cells: evidence for a novel mechanism involving inhibition of BCL6 signaling.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Transformed; DNA-Binding Proteins; Genes, myc; Genes, p53; Humans; Lymphoma, B-Cell; Lymphoma, Follicular; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-6; Resveratrol; Stilbenes | 2006 |
Endocrine disruptors and rat adrenocortical function: studies on freshly dispersed and cultured cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Benzhydryl Compounds; Benzophenones; Cell Count; Cell Culture Techniques; Cell Separation; Cells, Cultured; Corticosterone; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Phenols; Rats; Rats, Wistar; Resveratrol; Silymarin; Stilbenes; Time Factors; Zona Fasciculata; Zona Reticularis | 2006 |
Extractable amounts of trans-resveratrol in seed and berry skin in Vitis evaluated at the germplasm level.
Topics: Fruit; Genotype; Resveratrol; Seeds; Stilbenes; Vitis | 2006 |
Quantitation of trans-resveratrol and detection of its metabolites in human plasma and urine by high performance liquid chromatography.
Topics: Angiogenesis Inhibitors; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2007 |
Assignment of the 1H and 13C NMR signals of some hydroxyphenylcoumarins.
Topics: Carbon Isotopes; Chemistry, Pharmaceutical; Coumarins; Hydrogen; Magnetic Resonance Spectroscopy; Reference Standards; Resveratrol; Stilbenes | 2007 |
Effect of resveratrol on alcohol-induced mortality and liver lesions in mice.
Topics: Alanine Transaminase; Alcoholism; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drinking; Eating; Interleukin-1; Liver; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes; Transaminases; Tumor Necrosis Factor-alpha | 2006 |
In vitro electrophysiological mechanisms for antiarrhythmic efficacy of resveratrol, a red wine antioxidant.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Cells, Cultured; Dose-Response Relationship, Drug; Electrophysiology; Heart Conduction System; In Vitro Techniques; Male; Membrane Potentials; Myocardial Reperfusion Injury; Myocytes, Cardiac; Potassium Channels; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium Channels; Stilbenes; Treatment Outcome; Wine | 2007 |
Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells.
Topics: Annexin A5; Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Nucleus Size; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Resveratrol; Stilbenes; Thymidine; Tritium | 2006 |
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Topics: Acetylation; Adult; Animals; Dietary Fats; Energy Metabolism; Gene Expression Regulation; Humans; Insulin Resistance; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mitochondria, Muscle; Motor Activity; Muscle Fibers, Skeletal; Obesity; Oxidative Phosphorylation; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polymorphism, Single Nucleotide; Resveratrol; Sirtuin 1; Sirtuins; Specific Pathogen-Free Organisms; Stilbenes; Trans-Activators; Transcription Factors | 2006 |
The suppressive effect of resveratrol on protein kinase C theta in peripheral blood T lymphocytes in a rat liver transplantation model.
Topics: Animals; Gene Expression Regulation, Enzymologic; Isoenzymes; Liver Transplantation; Male; Models, Animal; Protein Kinase C; Protein Kinase C-theta; Rats; Rats, Sprague-Dawley; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; T-Lymphocytes; Vasodilator Agents | 2006 |
Effects of resveratrol in inflammatory arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cartilage; Female; Injections, Intra-Articular; Knee Joint; Lipopolysaccharides; Proteoglycans; Rabbits; Resveratrol; Stilbenes; Synovial Membrane | 2007 |
The red wine antioxidant resveratrol prevents cardiomyocyte injury following ischemia-reperfusion via multiple sites and mechanisms.
Topics: Animals; Antioxidants; Carotid Arteries; Dose-Response Relationship, Drug; Endothelial Cells; Heart; Humans; Hypoxia; In Vitro Techniques; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2007 |
Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D.
Topics: Caspase Inhibitors; Cathepsin D; Cathepsin L; Cathepsins; Cell Death; Cell Line; Colorectal Neoplasms; Cysteine Endopeptidases; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; HT29 Cells; Humans; Lysosomes; Resveratrol; Stilbenes; Time Factors | 2007 |
Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB.
Topics: Antioxidants; Cell Line; Combinatorial Chemistry Techniques; Cyclooxygenase 2 Inhibitors; Humans; NF-kappa B; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2006 |
Strong cardioprotective effect of resveratrol, a red wine polyphenol, on isolated rat hearts after ischemia/reperfusion injury.
Topics: Animals; Cardiotonic Agents; Heart Rate; In Vitro Techniques; Male; Malondialdehyde; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Phenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Wine | 2007 |
The effect of oil components on the physicochemical properties and drug delivery of emulsions: tocol emulsion versus lipid emulsion.
Topics: Animals; Antioxidants; Biphenyl Compounds; Carotid Stenosis; Chemistry, Pharmaceutical; Coconut Oil; Disease Models, Animal; Drug Carriers; Drug Compounding; Emulsions; Hemolysis; Male; Micelles; Oils; Particle Size; Phosphatidylcholines; Picrates; Plant Oils; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes; Surface-Active Agents; Technology, Pharmaceutical; Time Factors; Vitamin E | 2007 |
The dietary antioxidant resveratrol affects redox changes of PPARalpha activity.
Topics: Acyl-CoA Oxidase; Animals; Antioxidants; DNA; Electrophoretic Mobility Shift Assay; Glutathione; Maleates; Oxidation-Reduction; Oxidative Stress; PPAR alpha; Rats; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2007 |
Nongenomic activation of the GC-A enzyme by resveratrol and estradiol downstream from membrane estrogen receptors in human coronary arterial cells.
Topics: Cells, Cultured; Coronary Vessels; Cyclic GMP; Enzyme Inhibitors; Estradiol; Guanylate Cyclase; Humans; Muscle, Smooth, Vascular; Receptors, Estrogen; Resveratrol; Stilbenes | 2007 |
Neuroprotective effects of resveratrol against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats.
Topics: Acetylcholinesterase; Administration, Oral; Animals; Antioxidants; Behavior, Animal; Brain; Cognition Disorders; Colchicine; Glutathione; Injections, Intraventricular; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neuroprotective Agents; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Space Perception; Stilbenes; Tubulin Modulators | 2007 |
Resveratrol binds to the sulfonylurea receptor (SUR) and induces apoptosis in a SUR subtype-specific manner.
Topics: Animals; Apoptosis; ATP-Binding Cassette Transporters; Caspases; Cell Adhesion; Cell Line; Etoposide; Female; Humans; Hypoglycemic Agents; Islets of Langerhans; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Recombinant Proteins; Resveratrol; Stilbenes; Sulfonylurea Receptors; Transfection | 2007 |
Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati.
Topics: Borates; Chemical Fractionation; Chromatography, High Pressure Liquid; Fallopia japonica; Imidazoles; Microwaves; Resveratrol; Solvents; Stilbenes | 2007 |
Hopeaphenol: the first resveratrol tetramer in wines from North Africa.
Topics: Africa, Northern; Algeria; Chromatography, High Pressure Liquid; Flavonoids; Flavonols; Magnetic Resonance Spectroscopy; Phenols; Polyphenols; Resveratrol; Stilbenes; Wine | 2006 |
Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Animals, Newborn; Antioxidants; Cell Survival; Cytotoxins; DNA Damage; Dopamine; Dose-Response Relationship, Drug; Glutathione; Mesencephalon; Methylnitronitrosoguanidine; Neurons; Neuroprotective Agents; Niacinamide; Organ Culture Techniques; Quercetin; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Sirtuins; Sodium Azide; Stilbenes; Thrombin; Tumor Suppressor Protein p53 | 2007 |
Design and synthesis of compounds that extend yeast replicative lifespan.
Topics: Cell Line; Cell Proliferation; Cell Survival; Cellular Senescence; Dose-Response Relationship, Drug; Drug Design; Enzyme Activation; Flavonoids; Flavonols; Humans; Molecular Structure; Resveratrol; Saccharomyces cerevisiae; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
DNA damage induced by resveratrol and its synthetic analogues in the presence of Cu (II) ions: mechanism and structure-activity relationship.
Topics: Copper; DNA; DNA Damage; HL-60 Cells; Humans; Jurkat Cells; Models, Biological; Plasmids; Reactive Oxygen Species; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Structure-Activity Relationship | 2006 |
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Caspase 3; Cell Proliferation; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Multiple Myeloma; NF-kappa B; Proto-Oncogene Proteins c-akt; Pyrazines; Resveratrol; STAT3 Transcription Factor; Stilbenes; Syndecan-1; Thalidomide; Tumor Cells, Cultured | 2007 |
The rolB gene-induced overproduction of resveratrol in Vitis amurensis transformed cells.
Topics: Bacterial Proteins; beta-Glucosidase; Drug Resistance; p-Fluorophenylalanine; Phenylalanine; Plant Diseases; Plant Tumors; Plants, Genetically Modified; Resveratrol; Rhizobium; Stilbenes; Transfection; Vitis | 2007 |
HPLC-tandem mass spectrometric method to characterize resveratrol metabolism in humans.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Drug Stability; Humans; Lipoproteins, LDL; Male; Middle Aged; Quality Control; Resveratrol; Sensitivity and Specificity; Stereoisomerism; Stilbenes; Tandem Mass Spectrometry; Wine | 2007 |
In vino veritas: a tale of two sirt1s?
Topics: Acetylation; Administration, Oral; Aging; Animals; Diabetes Mellitus, Type 2; Energy Metabolism; Glucose; Homeostasis; Humans; Insulin; Longevity; Male; Mice; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors | 2006 |
Protection of lipids from oxidation by epicatechin, trans-resveratrol, and gallic and caffeic acids in intestinal model systems.
Topics: Animals; Antioxidants; Body Fluids; Caffeic Acids; Catechin; Gallic Acid; Intestinal Mucosa; Linoleic Acids; Lipid Peroxidation; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2006 |
Resveratrol and curcumin suppress immune response through CD28/CTLA-4 and CD80 co-stimulatory pathway.
Topics: Animals; Antigens, CD; Antigens, Differentiation; Antineoplastic Agents; B-Lymphocytes; B7-1 Antigen; CD28 Antigens; CD4-Positive T-Lymphocytes; CD40 Antigens; Cell Proliferation; Cell Survival; Cells, Cultured; Concanavalin A; CTLA-4 Antigen; Curcumin; Flow Cytometry; Immunoglobulin G; Lipopolysaccharides; Lymphocytes; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes | 2007 |
Determination of resveratrol in wine by photochemically induced second-derivative fluorescence coupled with liquid-liquid extraction.
Topics: Molecular Structure; Photochemistry; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Wine | 2007 |
Can we slow aging?
Topics: Aging; Humans; Longevity; Resveratrol; Stilbenes; United States; Wine | 2006 |
Statin and resveratrol in combination induces cardioprotection against myocardial infarction in hypercholesterolemic rat.
Topics: Animals; Apoptosis; beta Catenin; Drug Therapy, Combination; Gene Expression Regulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipid Metabolism; Male; Myocardial Infarction; Nitric Oxide Synthase Type III; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Protein Transport; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A | 2007 |
Inhibition of S1P by polyphenols prevents inflammation and angiogenesis: NFkappaB, a downstream effector?
Topics: Animals; Anti-Inflammatory Agents; Cell Movement; Flavonoids; Humans; Inflammation; Lysophospholipids; Neovascularization, Pathologic; NF-kappa B; Phenols; Polyphenols; Propiophenones; Resveratrol; Sphingosine; Stilbenes; Vitis | 2007 |
Resveratrol, a polyphenolic phytostilbene, inhibits endothelial monocyte chemotactic protein-1 synthesis and secretion.
Topics: Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; GTP-Binding Protein alpha Subunits, Gi-Go; Heme Oxygenase-1; Humans; Interleukin-1beta; NF-kappa B; Nitric Oxide; Promoter Regions, Genetic; Resveratrol; Ribonucleotide Reductases; RNA Stability; RNA, Messenger; Signal Transduction; Stilbenes; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2007 |
New resveratrol tetramers from the stem bark of Upuna borneensis.
Topics: Ericales; Molecular Structure; Plant Bark; Plant Extracts; Plant Stems; Resveratrol; Stilbenes | 2005 |
Two novel trimeric resveratrol derivatives from Cotylelobium lanceolatum.
Topics: Ericales; Molecular Structure; Resveratrol; Stilbenes | 2005 |
Synthesis and cytotoxic evaluation of a series of resveratrol derivatives.
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Drug Screening Assays, Antitumor; Humans; KB Cells; Molecular Structure; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2006 |
Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages.
Topics: Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Lipoproteins, LDL; NADP; Oxidative Stress; Resveratrol; Stilbenes | 2007 |
Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF-alpha.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Drug Therapy, Combination; Hot Temperature; Insulin; Male; Mice; Nitric Oxide; Pain; Pain Measurement; Phytotherapy; Plant Extracts; Plants, Medicinal; Resveratrol; Stilbenes; Streptozocin; Tumor Necrosis Factor-alpha | 2007 |
Biological activity of acetylated phenolic compounds.
Topics: Acetylation; Animals; Chromatography, High Pressure Liquid; Phenylethyl Alcohol; Platelet Activating Factor; Platelet Aggregation; Rabbits; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2007 |
Gentamicin-induced nephrotoxicity in rats ameliorated and healing effects of resveratrol.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Catalase; Creatinine; Gentamicins; Glutathione; Glutathione Transferase; Kidney; Kidney Diseases; Kidney Tubules; Lipid Peroxidation; Male; Malondialdehyde; Potassium; Rats; Rats, Wistar; Resveratrol; Sodium; Stilbenes; Urea | 2007 |
Protective effect of (4-methoxybenzylidene)-(3-methoxynophenyl)amine against neuronal cell death induced by oxygen and glucose deprivation in rat organotypic hippocampal slice culture.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Benzyl Compounds; Brain Ischemia; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Drug; Glucose; Hippocampus; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2007 |
Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels.
Topics: 4-Aminopyridine; Animals; Aorta, Thoracic; Benzimidazoles; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Large-Conductance Calcium-Activated Potassium Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Peptides; Potassium Chloride; Quinoxalines; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2007 |
Modulation of pregnane X receptor- and electrophile responsive element-mediated gene expression by dietary polyphenolic compounds.
Topics: Catechin; Cell Line, Tumor; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dietary Supplements; Flavonoids; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase-1; Humans; Phenols; Plant Extracts; Polyphenols; Pregnane X Receptor; Promoter Regions, Genetic; Quercetin; Receptors, Steroid; Response Elements; Resveratrol; Stilbenes; Syzygium; Thymus Plant | 2007 |
Resveratrol increases vascular oxidative stress resistance.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Hydrogen Peroxide; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
Resveratrol: ready for prime time?
Topics: Animals; Heart; Humans; Hypercholesterolemia; Resveratrol; Stilbenes | 2007 |
Attenuation of ischemia/reperfusion injury in rats by the anti-inflammatory action of resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood Pressure; Cell Adhesion Molecules; Enzyme Induction; Heart Function Tests; In Situ Nick-End Labeling; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2006 |
Comparison of extraction methods for the quantification of selected phytochemicals in peanuts (Arachis hypogaea).
Topics: Arachis; Chromatography, High Pressure Liquid; Isoflavones; Microwaves; Reproducibility of Results; Resveratrol; Sonication; Stilbenes | 2007 |
Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Brain; Diabetes Mellitus, Experimental; Hot Temperature; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Neuralgia; Nitric Oxide; Pain Threshold; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Tumor Necrosis Factor-alpha | 2007 |
Resveratrol: why it matters in HIV.
Topics: Animals; HIV Infections; Humans; Resveratrol; Stilbenes | 2006 |
The activation by estrogen receptor agonists of the BK(Ca)-channel in human cardiac fibroblasts.
Topics: Calcium; Estradiol; Estradiol Congeners; Fibroblasts; Fulvestrant; Heart; Humans; Large-Conductance Calcium-Activated Potassium Channels; Myocardium; Nitriles; Receptors, Estrogen; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors | 2007 |
[The study in resveratrol function to acute lung injury sourced from severe acute pancreatitis].
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Progression; Gene Expression Regulation; Lung; Male; Nitric Oxide Synthase Type II; Pancreatitis; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2006 |
Cerebral angiogenesis induced by resveratrol contributes to relieve cerebral ischemic-reperfusion injury.
Topics: Angiogenesis Inhibitors; Animals; Brain; Brain Ischemia; Humans; Models, Cardiovascular; Models, Neurological; Neovascularization, Physiologic; Reperfusion Injury; Resveratrol; Stilbenes | 2007 |
Bioactive bibenzyl derivatives and fluorenones from Dendrobium nobile.
Topics: Antioxidants; Bibenzyls; Biphenyl Compounds; Dendrobium; Drugs, Chinese Herbal; Fluorenes; Nitric Oxide; Picrates; Plant Stems; Plants, Medicinal; Resveratrol; Sesquiterpenes, Germacrane; Stilbenes | 2007 |
Resveratrol inhibits pancreatic cancer cell proliferation through transcriptional induction of macrophage inhibitory cytokine-1.
Topics: Antineoplastic Agents, Phytogenic; Bone Morphogenetic Proteins; Cell Division; Cell Line, Tumor; Dactinomycin; Gene Expression Regulation, Neoplastic; Growth Differentiation Factor 15; Humans; Nucleic Acid Synthesis Inhibitors; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Resveratrol; RNA, Small Interfering; Stilbenes; Transcription, Genetic; Transfection; Up-Regulation | 2007 |
Central nervous system protection by resveratrol in streptozotocin-induced diabetic rats.
Topics: Animals; Central Nervous System Diseases; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Free Radical Scavengers; Glutathione; Hyperglycemia; Lipid Peroxidation; Male; Malondialdehyde; Medulla Oblongata; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Spinal Cord; Stilbenes; Vasodilator Agents; Xanthine Oxidase | 2007 |
Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver.
Topics: Animals; Antioxidants; Catalase; Central Nervous System Depressants; Diet; Ethanol; Glutathione Peroxidase; Glutathione Reductase; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2007 |
Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Lung Neoplasms; Oxidation-Reduction; Phosphotransferases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sensitivity and Specificity; Stilbenes; Structure-Activity Relationship; Transcription, Genetic; Tumor Cells, Cultured | 2007 |
Resveratrol does not ameliorate muscle wasting in different types of cancer cachexia models.
Topics: Animals; Body Weight; Cachexia; Carcinoma, Lewis Lung; Disease Models, Animal; Energy Intake; Fish Oils; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscle, Skeletal; Neoplasms, Experimental; NF-kappa B; Organ Size; Random Allocation; Rats; Rats, Wistar; Resveratrol; Sarcoma, Yoshida; Stilbenes | 2007 |
Mesocarp localization of a bi-functional resveratrol/hydroxycinnamic acid glucosyltransferase of Concord grape (Vitis labrusca).
Topics: Acyltransferases; Amino Acid Sequence; Coumaric Acids; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucosides; Glucosyltransferases; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Structure; Phylogeny; Recombinant Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Stilbenes; Substrate Specificity; Vitis | 2007 |
Climate not cultivars in the NO-ing of red wines.
Topics: Cell Line; Climate; Flavonoids; Geography; Humans; Nitric Oxide; Phenols; Polyphenols; Resveratrol; Stilbenes; Up-Regulation; Vasodilator Agents; Vitis; Wine | 2007 |
Activation of endothelial nitric oxide synthase by red wine polyphenols: impact of grape cultivars, growing area and the vinification process.
Topics: Cell Line; Climate; Dose-Response Relationship, Drug; Endothelial Cells; Fermentation; Flavonoids; Genes, Reporter; Geography; Humans; Luciferases; Nitric Oxide; Nitric Oxide Synthase; Phenols; Polyphenols; Resveratrol; Stilbenes; Up-Regulation; Vasodilator Agents; Vitis; Wine | 2007 |
Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatography, High Pressure Liquid; Enzyme Induction; Enzymes; Flow Cytometry; Glucuronosyltransferase; Humans; Liver Neoplasms; Mass Spectrometry; Metabolic Detoxication, Phase II; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfotransferases; Time Factors; Tritium | 2007 |
Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Neural Conduction; Oxidative Stress; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resveratrol; Sciatic Nerve; Stilbenes | 2007 |
[Cheers !].
Topics: Acetylation; Animals; Antioxidants; Caloric Restriction; Heat-Shock Proteins; Humans; Insulin Resistance; Longevity; Mice; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Processing, Post-Translational; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors; Wine | 2007 |
Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1.
Topics: Apigenin; Arylsulfotransferase; Catechin; Cell Proliferation; Diet; Flavonoids; Humans; Kinetics; Phenols; Polymorphism, Single Nucleotide; Polyphenols; Quercetin; Recombinant Proteins; Resveratrol; Stilbenes; Sulfates; Sulfotransferases; Tumor Cells, Cultured | 2007 |
Stereospecific determination of cis- and trans-resveratrol in rat plasma by HPLC: application to pharmacokinetic studies.
Topics: Animals; Caffeine; Calibration; Chromatography, High Pressure Liquid; Drug Stability; Molecular Structure; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stereoisomerism; Stilbenes | 2007 |
Resveratrol-induced cell inhibition of growth and apoptosis in MCF7 human breast cancer cells are associated with modulation of phosphorylated Akt and caspase-9.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 9; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Oncogene Protein v-akt; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes | 2006 |
Live forever?
Topics: Antioxidants; Humans; Longevity; Resveratrol; Stilbenes; Wine | 2007 |
Characterization of immunological activities of peanut stilbenoids, arachidin-1, piceatannol, and resveratrol on lipopolysaccharide-induced inflammation of RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Arachis; Cell Line; Inflammation; Lipopolysaccharides; Macrophages; Mice; Resveratrol; Stilbenes | 2007 |
Quinone reductase induction activity of methoxylated analogues of resveratrol.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biomarkers; Cell Line, Tumor; Enzyme Induction; Mice; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes | 2007 |
A study of the formulation design of acoustically active lipospheres as carriers for drug delivery.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coconut Oil; Drug Carriers; Drug Compounding; Drug Delivery Systems; Emulsions; Erythrocytes; Excipients; Fluorocarbons; Hemolysis; Humans; In Vitro Techniques; Liposomes; Particle Size; Plant Oils; Poloxamer; Polyethylene Glycols; Resveratrol; Stilbenes; Ultrasonics | 2007 |
Resveratrol sensitization of DU145 prostate cancer cells to ionizing radiation is associated to ceramide increase.
Topics: Cell Death; Cell Line, Tumor; Ceramides; Humans; Male; Prostatic Neoplasms; Radiation-Sensitizing Agents; Resveratrol; Stilbenes | 2007 |
Resveratrol ameliorates experimental autoimmune myocarditis.
Topics: Animals; Autoimmune Diseases; Cardiomegaly; Cardiomyopathy, Dilated; Cardiotonic Agents; Chemotaxis, Leukocyte; Disease Models, Animal; Electrocardiography; Female; Inflammation; Leukocytes, Mononuclear; Myocarditis; Myosins; Rats; Rats, Inbred Lew; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Resveratrol attenuates ischemia - reperfusion-induced leukocyte - endothelial cell adhesive interactions and prolongs allograft survival across the MHC barrier.
Topics: Animals; Cell Adhesion; Endothelial Cells; Endothelium, Vascular; Graft Survival; Histocompatibility; Leukocyte Rolling; Leukocytes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Skin Transplantation; Stilbenes; Transplantation, Homologous; Venules | 2007 |
The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation.
Topics: Animals; Cell Line; Chalcones; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Energy Metabolism; Gene Expression Profiling; Gene Expression Regulation; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kaempferols; Myoblasts; Oxygen Consumption; Rats; Resveratrol; RNA Interference; Stilbenes; Triiodothyronine | 2007 |
Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells.
Topics: Adenosine Triphosphatases; Animals; Calcium Channel Blockers; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Egtazic Acid; Estradiol; Fulvestrant; Genistein; Leydig Cells; Male; Mibefradil; Mice; Phosphoproteins; Phytoestrogens; Progesterone; Quercetin; Receptors, Estrogen; Resveratrol; RNA, Messenger; Stilbenes; Stimulation, Chemical; Vanadates; Verapamil | 2007 |
Biotransformation of piceid in Polygonum cuspidatum to resveratrol by Aspergillus oryzae.
Topics: Aspergillus oryzae; Biomass; Biotransformation; Fallopia japonica; Fermentation; Glucosides; Hydrolysis; Molecular Structure; Resveratrol; Stilbenes; Sulfuric Acids | 2007 |
Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats.
Topics: Androstadienes; Animals; Antioxidants; Blood Glucose; Carboxy-Lyases; Chromones; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Hypoglycemic Agents; Liver; Male; Morpholines; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Vitis; Wortmannin | 2007 |
Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cells.
Topics: Actins; Adenocarcinoma; Breast Neoplasms; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Movement; Cytoskeleton; Dose-Response Relationship, Drug; Epidermal Growth Factor; Estradiol; Estrogens; Female; Genes, Dominant; Humans; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Pseudopodia; rac GTP-Binding Proteins; Recombinant Fusion Proteins; Resveratrol; Stilbenes; Transfection | 2007 |
Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells.
Topics: Apoptosis; Casein Kinase II; Caspase 3; Catechin; Cell Proliferation; Drug Therapy, Combination; Humans; Immunoblotting; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Resveratrol; Signal Transduction; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2007 |
Acute dilatation to phytoestrogens and estrogen receptor subtypes expression in small arteries from women with coronary heart disease.
Topics: Aged; Arteries; Case-Control Studies; Endothelium, Vascular; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genistein; Humans; Middle Aged; Myocardial Infarction; Phenols; Phytoestrogens; Postmenopause; Pyrazoles; Resveratrol; Stilbenes; Subcutaneous Fat, Abdominal; Vasodilation; Vasodilator Agents | 2008 |
Mitochondria biogenesis induced by resveratrol against brain ischemic stroke.
Topics: Animals; Antioxidants; Brain Ischemia; DNA, Mitochondrial; Flavonoids; Humans; Hypoxia; Mice; Mitochondria; Models, Biological; Phenols; Polyphenols; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Stilbenes; Stroke | 2007 |
Role of FoxO1 in FFA-induced oxidative stress in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Diabetes Mellitus; Fatty Acids, Nonesterified; Forkhead Box Protein O1; Forkhead Transcription Factors; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
Effect of wine phenolics on cytokine-induced C-reactive protein expression.
Topics: C-Reactive Protein; Cell Line; Cytokines; Gene Expression; Humans; MAP Kinase Signaling System; Phenols; Quercetin; Resveratrol; RNA, Messenger; Stilbenes; Wine | 2007 |
Resveratrol-induced mitochondrial dysfunction and apoptosis are associated with Ca2+ and mCICR-mediated MPT activation in HepG2 cells.
Topics: Apoptosis; Calcium Signaling; Cell Line, Tumor; Cell Membrane Permeability; Cytochromes c; Dose-Response Relationship, Drug; Humans; Ion Channel Gating; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Resveratrol; Stilbenes; Time Factors | 2007 |
Interaction of resveratrol and its trimethyl and triacetyl derivatives with biomembrane models studied by differential scanning calorimetry.
Topics: Absorption; Acetylation; Calorimetry, Differential Scanning; Dimyristoylphosphatidylcholine; Kinetics; Liposomes; Methylation; Phase Transition; Resveratrol; Stilbenes | 2007 |
Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat.
Topics: Animals; Antioxidants; Brain; Catalase; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Lipid Peroxidation; Male; Malondialdehyde; Nerve Tissue Proteins; Peroxidases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2007 |
Resveratrol induces apoptosis in chemoresistant cancer cells via modulation of AMPK signaling pathway.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Drug Resistance, Neoplasm; Etoposide; HT29 Cells; Humans; Multienzyme Complexes; Protein Serine-Threonine Kinases; Resveratrol; Signal Transduction; Stilbenes | 2007 |
Antioxidative effects of plant polyphenols: from protection of G protein signaling to prevention of age-related pathologies.
Topics: Aged, 80 and over; Aging; Alzheimer Disease; Antioxidants; Curcumin; Female; Flavonoids; Genistein; GTP-Binding Proteins; Humans; Oxidative Stress; Phenols; Plant Preparations; Polyphenols; Resveratrol; Signal Transduction; Stilbenes | 2007 |
Protective effects of piceatannol against beta-amyloid-induced neuronal cell death.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Dose-Response Relationship, Drug; Neurons; Neuroprotective Agents; PC12 Cells; Peptide Fragments; Rats; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits IL-1 beta-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cartilage, Articular; Caspase 3; Caspase Inhibitors; Cells, Cultured; Chondrocytes; Collagen Type II; Enzyme Activation; Humans; Hydrolysis; Interleukin-1beta; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Resveratrol; Stilbenes | 2007 |
Neuroprotective effects of natural products: interaction with intracellular kinases, amyloid peptides and a possible role for transthyretin.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Biological Products; Catechin; Cells, Cultured; Flavonoids; Hippocampus; Maze Learning; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Peptides; Phenols; Phosphotransferases; Polyphenols; Prealbumin; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Tretinoin | 2007 |
[Ideas, research and ethics of scientific journals].
Topics: Alcoholic Intoxication; Animals; Chemical and Drug Induced Liver Injury; Ethics, Professional; Liver Diseases; Mice; Parenteral Nutrition, Total; Periodicals as Topic; Professional Misconduct; Publishing; Research Support as Topic; Resveratrol; Stilbenes | 2007 |
An effective sample preparation approach for screening the anticancer compound piceatannol using HPLC coupled with UV and fluorescence detection.
Topics: Antineoplastic Agents; Arachis; Chromatography, High Pressure Liquid; Fallopia japonica; Plant Extracts; Reproducibility of Results; Resveratrol; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stilbenes; Vitis | 2007 |
Resveratrol/phloroglucinol glycosides from the roots of Lysidice rhodostegia.
Topics: Antioxidants; Fabaceae; Glycosides; Molecular Conformation; Phloroglucinol; Plant Extracts; Plant Roots; Resveratrol; Stilbenes | 2007 |
Vibrational spectroscopy of resveratrol.
Topics: Resveratrol; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Stilbenes; Vibration | 2007 |
Obesity: do grapes hold the answer?
Topics: Animals; Diet; Enzyme Activation; Flavonoids; Humans; Mice; Obesity; Phenols; Polyphenols; Resveratrol; Sirtuins; Stilbenes; Vitis | 2007 |
Resveratrol prevents fibrosis, NF-kappaB activation and TGF-beta increases induced by chronic CCl4 treatment in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bilirubin; Carbon Tetrachloride; Glutathione; Glutathione Disulfide; Glycogen; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; NF-kappa B; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Transforming Growth Factor beta | 2008 |
Resveratrol stimulates AMP kinase activity in neurons.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Enzyme Activation; Ganglia, Spinal; Male; Mice; Mitochondria; Neurites; Neurons; Neurons, Afferent; Phosphorylation; Protein Serine-Threonine Kinases; Resveratrol; Ribonucleotides; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Inhibition of human recombinant cytochromes P450 CYP1A1 and CYP1B1 by trans-resveratrol methyl ethers.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Enzyme Inhibitors; Humans; Methyl Ethers; Recombinant Proteins; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibition of Propionibacterium acnes.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoyl Peroxide; Dose-Response Relationship, Drug; Erythromycin; Keratolytic Agents; Microbial Sensitivity Tests; Propionibacterium acnes; Resveratrol; Stilbenes | 2007 |
Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Endoplasmic Reticulum; Gene Expression Regulation; Glucose; Glycoproteins; Humans; Lactic Acid; Mice; Molecular Weight; Oxidoreductases; PPAR gamma; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Evidence for a trade-off between survival and fitness caused by resveratrol treatment of Caenorhabditis elegans.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Survival; Cellular Senescence; Flavonoids; Helminth Proteins; Metabolic Networks and Pathways; Models, Chemical; Oxidative Stress; Paraquat; Phenols; Polyphenols; Resveratrol; Stilbenes; Time Factors; Wine | 2007 |
Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation; Golgi Apparatus; Humans; Intramolecular Oxidoreductases; Levodopa; Melanins; Melanocytes; Microphthalmia-Associated Transcription Factor; Resveratrol; RNA Processing, Post-Transcriptional; Stilbenes; Transcription, Genetic | 2007 |
Determination of trans-resveratrol in wine by micro-HPLC with fluorescence detection.
Topics: Calibration; Chromatography, High Pressure Liquid; Reproducibility of Results; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Wine | 2007 |
Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport; Cell Line; Enzyme Activation; Glucose; Insulin; Mice; Models, Biological; Multienzyme Complexes; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2007 |
The influence of wine polyphenols on reactive oxygen and nitrogen species production by murine macrophages RAW 264.7.
Topics: Animals; Catechin; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide Synthase Type II; Oxidative Stress; Phenols; Polyphenols; Quercetin; Reactive Nitrogen Species; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors; Wine | 2008 |
Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells.
Topics: Anticarcinogenic Agents; Carcinoma; Chromones; Female; Flavonoids; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Neovascularization, Pathologic; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Phosphoinositide-3 Kinase Inhibitors; Repressor Proteins; Resveratrol; RNA, Small Interfering; Stilbenes; Transcriptional Activation; Transfection; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2007 |
Differential expression of genes induced by resveratrol in human breast cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Fibrocystic Breast Disease; Gene Expression Regulation, Neoplastic; Humans; Receptors, Estrogen; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Transcription, Genetic | 2006 |
Resveratrol improves ifosfamide-induced Fanconi syndrome in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Antioxidants; Blood Urea Nitrogen; Cytokines; Fanconi Syndrome; Female; Glutathione; Ifosfamide; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Luminescence; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Urinary Bladder | 2007 |
In which period of injury is resveratrol treatment effective: ischemia or reperfusion?
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Enzyme Inhibitors; Hindlimb; Immunohistochemistry; Ischemic Preconditioning; Lumbar Vertebrae; Malondialdehyde; Microscopy, Electron; Movement; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Peroxidase; Rabbits; Recovery of Function; Reperfusion; Reperfusion Injury; Resveratrol; Spinal Cord Injuries; Stilbenes; Time Factors; Treatment Outcome | 2007 |
Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway.
Topics: Breast Neoplasms; Glycogen Synthase Kinase 3; Humans; Male; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostatic Neoplasms; Protein Binding; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Receptors, Androgen; Receptors, Estrogen; Resveratrol; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2007 |
Prevention of concentric hypertrophy and diastolic impairment in aortic-banded rats treated with resveratrol.
Topics: Animals; Aorta; Dose-Response Relationship, Drug; Hypertension; Hypertrophy, Left Ventricular; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Stroke Volume; Treatment Outcome; Ultrasonography; Vasodilator Agents; Ventricular Dysfunction, Left | 2007 |
Resveratrol attenuates oxidative-induced DNA damage in C6 Glioma cells.
Topics: Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Glioma; Hydrogen Peroxide; Mice; Oxidative Stress; Propidium; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits proliferation of cultured rat cardiac fibroblasts: correlated with NO-cGMP signaling pathway.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiovascular Agents; Cell Proliferation; Cell Size; Cells, Cultured; Cyclic GMP; Fibroblasts; Intracellular Space; L-Lactate Dehydrogenase; Male; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2007 |
Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes.
Topics: Cell Line; Cell Separation; Cell Survival; Chromones; Flavonoids; Flow Cytometry; Gene Expression Regulation; Humans; Kinetics; Monocytes; Morpholines; NG-Nitroarginine Methyl Ester; Reactive Oxygen Species; Receptors, CCR2; Resveratrol; RNA, Messenger; Stilbenes | 2007 |
Simultaneous determination of trans-resveratrol-3-O-glucoside and its two metabolites in rat plasma using liquid chromatography with ultraviolet detection.
Topics: Animals; Chromatography, Liquid; Glucosides; Rats; Rats, Wistar; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stilbenes | 2007 |
Molecular imprinted polymer-based chemiluminescence imaging sensor for the detection of trans-resveratrol.
Topics: Luminescent Measurements; Microarray Analysis; Microscopy, Electron, Scanning; Microspheres; Polyvinyl Alcohol; Resveratrol; Stilbenes | 2007 |
Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Breast Neoplasms; Cell Line, Tumor; Estrogen Replacement Therapy; Estrogens; Female; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; Humans; Mice; Osteoporosis, Postmenopausal; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Resveratrol; Risk Factors; src-Family Kinases; Stilbenes; Transforming Growth Factor beta | 2007 |
Inhibition of gap junctional intercellular communication and activation of mitogen-activated protein kinase by tumor-promoting organic peroxides and protection by resveratrol.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Cell Communication; Dose-Response Relationship, Drug; Epithelial Cells; Gap Junctions; Glutathione; Humans; Liver; Mitogen-Activated Protein Kinases; Oxidants; Peroxides; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Time Factors | 2007 |
Effect of formaldehyde and resveratrol on the viability of Vero, HepG2 and MCF-7 cells.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Chlorocebus aethiops; Disinfectants; Formaldehyde; Liver Neoplasms; Receptors, Estrogen; Resveratrol; Stilbenes; Vero Cells | 2007 |
[Effects of matrine, oxymatrine and resveratrol on HERG channel expression].
Topics: Alkaloids; Anti-Arrhythmia Agents; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluorescent Antibody Technique; Humans; Matrines; Membrane Potentials; Patch-Clamp Techniques; Plants, Medicinal; Quinolizines; Resveratrol; Sophora; Stilbenes | 2007 |
[Role of formaldehyde and its reaction products in mechanism of action of some plant ingredients].
Topics: Angiogenesis Inhibitors; Formaldehyde; Indicators and Reagents; Plant Extracts; Plants; Resveratrol; Stilbenes | 2007 |
[Resveratrol restored the structural and functional association between M3 receptor and connexin 43 gap junction proteins in ischemia-reperfusion injury of isolated rat heart].
Topics: Animals; Connexin 43; Electrocardiography; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Protective Agents; Random Allocation; Rats; Rats, Wistar; Receptor, Muscarinic M3; Resveratrol; Stilbenes; Superoxide Dismutase | 2007 |
De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity.
Topics: Caco-2 Cells; Cell Proliferation; Ceramides; Enzyme Inhibitors; Humans; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; PPAR gamma; Proto-Oncogene Proteins c-myc; Resveratrol; Spermine; Stilbenes | 2007 |
Adenosine arrests apoptosis in lymphocytes but not in phagocytes from primary leucocyte cultures of the teleost fish, Sparus aurata L.
Topics: Adenosine; Animals; Apoptosis; Cells, Cultured; Lymphocytes; Microscopy, Electron, Transmission; Phagocytes; Resveratrol; Sea Bream; Staurosporine; Stilbenes | 2007 |
Do we age on Sirt1 expression?
Topics: Aging; Caloric Restriction; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Longevity; Myocardium; Oxidative Stress; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Chronic resveratrol enhances endothelium-dependent relaxation but does not alter eNOS levels in aorta of spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Endothelium; Hydrogen Peroxide; Hypertension; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents | 2007 |
Neuroprotective effects of resveratrol against traumatic brain injury in immature rats.
Topics: Animals; Animals, Newborn; Antioxidants; Anxiety; Brain Injuries; Cell Death; Cognition Disorders; Hippocampus; Injections, Intraperitoneal; Memory; Memory Disorders; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Treatment Outcome | 2007 |
Resveratrol-induced apoptosis is associated with activation of p53 and inhibition of protein translation in T47D human breast cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Poly Adenosine Diphosphate Ribose; Protein Biosynthesis; Resveratrol; Ribosomal Protein S6; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2007 |
Resveratrol oligomers from Vitis amurensis attenuate beta-amyloid-induced oxidative stress in PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Caspase 3; Cell Survival; DNA Fragmentation; Enzyme Activation; Molecular Structure; Oxidative Stress; PC12 Cells; Peptide Fragments; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Vitis | 2007 |
Resveratrol and trimethylated resveratrol protect from acute liver damage induced by CCl4 in the rat.
Topics: Acute Disease; Alanine Transaminase; Animals; Antioxidants; Carbon Tetrachloride Poisoning; Disease Models, Animal; gamma-Glutamyltransferase; Glutathione; Glutathione Disulfide; Lipid Peroxidation; Liver; Liver Diseases; Male; Methylation; Molecular Structure; Rats; Rats, Wistar; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Resveratrol is a class IA phosphoinositide 3-kinase inhibitor.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Enzyme Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Mice; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Ribonucleotide Reductases; Signal Transduction; Sirtuins; Stilbenes | 2007 |
Resveratrol-induced growth inhibition in MDA-MB-231 breast cancer cells is associated with mitogen-activated protein kinase signaling and protein translation.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Enzyme Activation; Female; Humans; MAP Kinase Signaling System; Neoplasm Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Protein Kinase Inhibitors; Resveratrol; Ribosomal Protein S6; Serum; Stilbenes | 2007 |
Resveratrol increases glutamate uptake, glutathione content, and S100B secretion in cortical astrocyte cultures.
Topics: Animals; Antioxidants; Astrocytes; Cells, Cultured; Glial Fibrillary Acidic Protein; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Nerve Growth Factors; Rats; Rats, Wistar; Resveratrol; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stilbenes | 2007 |
Inhibition of the activity of human lymphocyte Kv1.3 potassium channels by resveratrol.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Kv1.3 Potassium Channel; Lymphocytes; Membrane Potentials; Resveratrol; Stilbenes; Time Factors | 2006 |
Effects of phytoestrogens and 17beta-estradiol on vasoconstriction elicited by reactive oxygen species.
Topics: Animals; Cattle; Coronary Vessels; Estradiol; Genistein; Hydrogen Peroxide; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oxygen; Phytoestrogens; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Vasoconstriction | 2007 |
Developing a high-throughput system for the screening of cytochrome P450 1A1--inhibitory polyphenols.
Topics: Cell Line, Tumor; Cytochrome P-450 CYP1A1; Flavonoids; Humans; Microsomes; Recombinant Proteins; Resveratrol; Stilbenes; Toxicity Tests; Transfection | 2007 |
Dual bioactivity of resveratrol fatty alcohols: differentiation of neural stem cells and modulation of neuroinflammation.
Topics: Animals; Cell Differentiation; Cell Line; Fatty Alcohols; Inflammation; Mice; Nervous System; Resveratrol; Stem Cells; Stilbenes | 2007 |
Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: activation of SIRT2, an NAD-dependent tubulin deacetylase.
Topics: Acetylation; Animals; Axons; Cells, Cultured; Drug Resistance; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubules; Resveratrol; RNA, Small Interfering; Sirtuin 2; Sirtuins; Stilbenes; Tubulin; Wallerian Degeneration | 2007 |
Low concentrations of resveratrol potentiate the antiplatelet effect of prostaglandins.
Topics: Cardiotonic Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Drug Synergism; Enzyme Activation; Humans; Phosphorylation; Platelet Aggregation Inhibitors; Prostaglandins; Protein Kinase C; Resveratrol; src-Family Kinases; Stilbenes | 2007 |
[Study on the effect of resveratrol on metastasis-associated ability of ovarian carcinoma HO-8910PM cells in vitro].
Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drugs, Chinese Herbal; Female; Flow Cytometry; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Plants, Medicinal; Resveratrol; Stilbenes | 2007 |
Transgenic alfalfa that accumulates piceid (trans-resveratrol-3-O-beta-D-glucopyranoside) requires the presence of beta-glucosidase to inhibit the formation of aberrant crypt foci in the colon of CF-1 mice.
Topics: Acyltransferases; Animals; beta-Glucosidase; Colonic Neoplasms; Disease Models, Animal; Female; Glucosides; Humans; Medicago sativa; Mice; Mice, Inbred Strains; Plants, Genetically Modified; Precancerous Conditions; Random Allocation; Resveratrol; Stilbenes | 2007 |
Resveratrol enhances insulin secretion by blocking K(ATP) and K(V) channels of beta cells.
Topics: Animals; Blood Glucose; Cell Line, Tumor; Cricetinae; Diabetes Mellitus, Experimental; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Membrane Potentials; Mice; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
Production and secretion of resveratrol in hairy root cultures of peanut.
Topics: Arachis; Gas Chromatography-Mass Spectrometry; Isomerism; Molecular Structure; Plant Roots; Resveratrol; Rhizobium; Stilbenes | 2007 |
Resveratrol-induced inhibition of insulin secretion from rat pancreatic islets: evidence for pivotal role of metabolic disturbances.
Topics: Animals; Carrier Proteins; Cell Survival; Colforsin; Estradiol; Fulvestrant; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Rats; Rats, Wistar; Receptors, Estrogen; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2007 |
cis- and trans-Resveratrol are glucuronidated in rat brain, olfactory mucosa and cultured astrocytes.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Cricetinae; Cricetulus; Glucuronides; Glucuronosyltransferase; In Vitro Techniques; Isoenzymes; Microsomes, Liver; Olfactory Mucosa; Rats; Rats, Wistar; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes | 2007 |
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.
Topics: Acetylation; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Cells, Cultured; Cyclin-Dependent Kinase 5; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Mutation; Nerve Degeneration; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2007 |
Comparative analysis of the effects of resveratrol in two apoptotic models: inhibition of complex I and potassium deprivation in cerebellar neurons.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Animals, Newborn; Antioxidants; Apoptosis; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Electron Transport Complex I; Gene Expression Regulation; Neurons; Potassium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirtuin 1; Sirtuins; Stilbenes; Time Factors | 2007 |
Benzo[a]pyrene-induced cytochrome P450 1A and DNA binding in cultured trout hepatocytes - inhibition by plant polyphenols.
Topics: Animals; Benzo(a)pyrene; Cells, Cultured; Cytochrome P-450 Enzyme System; DNA; Flavones; Flavonoids; Hepatocytes; Phenols; Plants; Polyphenols; Protein Binding; Resveratrol; Stilbenes; Trout | 2007 |
Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation: protective role of Mediterranean diet polyphenolic antioxidants.
Topics: Antioxidants; Cell Adhesion; Cells, Cultured; Diet, Mediterranean; Dose-Response Relationship, Drug; Endothelial Cells; Flavonoids; Homocysteine; Humans; Hyperhomocysteinemia; I-kappa B Proteins; Monocytes; Mutation; NADPH Oxidases; Phenols; Phenylethyl Alcohol; Phosphorylation; Polyphenols; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Protein Transport; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor RelA; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2007 |
Effect of resveratrol on proliferation and differentiation of embryonic cardiomyoblasts.
Topics: Animals; Cell Differentiation; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Myoblasts, Cardiac; Myocytes, Cardiac; Rats; Resveratrol; Stilbenes | 2007 |
Resveratrol protects vascular endothelial cell from ox-LDL-induced reduction in antithrombogenic activity.
Topics: Antioxidants; Blood Platelets; Calcium; Cells, Cultured; Coculture Techniques; Cyclic GMP; Endothelial Cells; Humans; Intracellular Membranes; Lipoproteins, LDL; Nitric Oxide; Nitric Oxide Synthase Type III; Osmolar Concentration; Platelet Aggregation; Resveratrol; Stilbenes; Thrombosis | 2007 |
Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures.
Topics: Animals; Astrocytes; Cerebral Cortex; Glutamic Acid; Glutathione; Hydrogen Peroxide; Immunohistochemistry; Nerve Growth Factors; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stilbenes | 2008 |
Transport of a cancer chemopreventive polyphenol, resveratrol: interaction with serum albumin and hemoglobin.
Topics: Animals; Anticarcinogenic Agents; Binding Sites; Biological Transport, Active; Cattle; Hemoglobins; Humans; In Vitro Techniques; Models, Molecular; Protein Conformation; Resveratrol; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry; Stilbenes | 2007 |
Novel method for quantitative determination of amyloid fibrils of alpha-synuclein and amyloid beta/A4 protein by using resveratrol.
Topics: alpha-Synuclein; Amyloid; Amyloid beta-Peptides; Amyloidosis; Benzothiazoles; Humans; Protein Structure, Quaternary; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thiazoles | 2007 |
A compound in red wine makes mice live longer, healthier.
Topics: Animals; Antioxidants; Longevity; Mice; Resveratrol; Stilbenes; Wine | 2007 |
Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats.
Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Ligation; Male; Malondialdehyde; Middle Cerebral Artery; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Long-Evans; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2007 |
New insights into mechanism for the effect of resveratrol preconditioning against cerebral ischemic stroke: Possible role of matrix metalloprotease-9.
Topics: Blood-Brain Barrier; Brain Ischemia; Humans; Matrix Metalloproteinase 9; Models, Neurological; Neovascularization, Pathologic; Resveratrol; Stilbenes; Vasodilator Agents | 2008 |
Resveratrol protects SH-SY5Y neuroblastoma cells from apoptosis induced by dopamine.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cytoprotection; Dopamine; Humans; Membrane Potential, Mitochondrial; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2007 |
'Bridged' stilbene derivatives as selective cyclooxygenase-1 inhibitors.
Topics: Animals; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Indenes; Male; Models, Molecular; Molecular Structure; Muscles; Naphthalenes; Resveratrol; Stilbenes; Structure-Activity Relationship | 2007 |
Combinatorial synthesis, reversed-phase and normal-phase high-performance liquid chromatography elution data and liquid chromatography/positive atmospheric pressure chemical ionization tandem mass spectra of methoxylated and glycosylated resveratrol analo
Topics: Antineoplastic Agents, Phytogenic; Atmosphere; Chromatography, High Pressure Liquid; Combinatorial Chemistry Techniques; Glycosylation; Phenols; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2007 |
Induction of apoptosis by rhapontin having stilbene moiety, a component of rhubarb (Rheum officinale Baillon) in human stomach cancer KATO III cells.
Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Free Radical Scavengers; Humans; Molecular Structure; Resveratrol; Rheum; Stilbenes; Time Factors | 2007 |
Resveratrol-induced depression of the mechanical and electrical activities of the rat heart is reversed by glyburide: evidence for possible K(ATP) channels activation.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Depression, Chemical; Female; Glyburide; Heart; Male; Myocardial Contraction; Nitric Oxide; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
Chronic treatment with resveratrol induces redox stress- and ataxia telangiectasia-mutated (ATM)-dependent senescence in p53-positive cancer cells.
Topics: Anticarcinogenic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; HCT116 Cells; Humans; Mitochondria; Neoplasms; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2007 |
Resveratrol induces apoptosis, influences IL-6 and exerts immunomodulatory effect on mouse lymphocytic leukemia both in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; BALB 3T3 Cells; Cell Line, Tumor; Interleukin-6; Leukemia, Lymphoid; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Resveratrol; Stilbenes | 2007 |
Acteoside inhibits human promyelocytic HL-60 leukemia cell proliferation via inducing cell cycle arrest at G0/G1 phase and differentiation into monocyte.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Differentiation; Cell Division; Epidermal Growth Factor; G1 Phase; Glucosides; HL-60 Cells; Humans; Muscle Cells; Phenols; Resting Phase, Cell Cycle; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2007 |
Does resveratrol activate yeast Sir2 in vivo?
Topics: Cellular Senescence; Histone Deacetylases; Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Sirtuins; Stilbenes | 2007 |
Molecular mechanisms of resveratrol (3,4,5-trihydroxy-trans-stilbene) and its interaction with TNF-related apoptosis inducing ligand (TRAIL) in androgen-insensitive prostate cancer cells.
Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Caspases; Cell Survival; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Neoplasm; Fas-Associated Death Domain Protein; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured | 2007 |
Moderate consumption of red wine (cabernet sauvignon) improves ischemia-induced neovascularization in ApoE-deficient mice: effect on endothelial progenitor cells and nitric oxide.
Topics: Adult Stem Cells; Animals; Apolipoproteins E; Cell Movement; Cells, Cultured; Endothelium, Vascular; Hindlimb; Humans; Hypercholesterolemia; Ischemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Nitric Oxide; Resveratrol; Stilbenes; Wine | 2007 |
Resveratrol inhibits nitric oxide and prostaglandin E2 production by lipopolysaccharide-activated C6 microglia.
Topics: Animals; Astrocytoma; Cell Division; Cell Line, Tumor; Cell Nucleus; Cyclooxygenase 2; Dinoprostone; Gene Expression; Lipopolysaccharides; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits heregulin-beta1-mediated matrix metalloproteinase-9 expression and cell invasion in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neuregulin-1; Phosphorylation; Receptor, ErbB-2; Resveratrol; Stilbenes; Tissue Inhibitor of Metalloproteinases | 2008 |
SIRT1 activation confers neuroprotection in experimental optic neuritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axonal Transport; Axons; Dose-Response Relationship, Drug; Electroretinography; Mice; Mice, Inbred Strains; Neuroprotective Agents; Niacinamide; Optic Neuritis; Photoreceptor Cells, Vertebrate; Pyridinium Compounds; Resveratrol; Retinal Ganglion Cells; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
p38 mitogen-activated protein kinase mediates sidestream cigarette smoke-induced endothelial permeability.
Topics: Blood-Air Barrier; Blotting, Western; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Antibody Technique; Humans; Imidazoles; Myosin Light Chains; p38 Mitogen-Activated Protein Kinases; Pulmonary Artery; Pyridines; Resveratrol; rho GTP-Binding Proteins; Stilbenes; Tobacco Smoke Pollution | 2007 |
Constitutive expression of a grapevine stilbene synthase gene in transgenic hop (Humulus lupulus L.) yields resveratrol and its derivatives in substantial quantities.
Topics: Acyltransferases; Gene Expression; Humulus; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis | 2007 |
Different sorption behaviors for wine polyphenols in contact with oak wood.
Topics: Adsorption; Anthocyanins; Flavonoids; Glucosides; Kinetics; Phenols; Polyphenols; Quercus; Resveratrol; Stilbenes; Wine; Wood | 2007 |
Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase.
Topics: Animals; Apoptosis; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression Regulation; Heart Diseases; Heme Oxygenase (Decyclizing); In Situ Nick-End Labeling; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; RNA, Messenger; Stilbenes; Streptozocin; Superoxide Dismutase; Thioredoxins; Vascular Endothelial Growth Factor A | 2007 |
Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production.
Topics: Animals; Antioxidants; Aorta; Apoptosis; Biopterins; Cell Cycle; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Female; Guanosine Triphosphate; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Resveratrol; Stilbenes | 2007 |
[Application of macroporous resin in purification for effective part from Polygonum cuspidatum].
Topics: Adsorption; Anthraquinones; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Plants, Medicinal; Resins, Synthetic; Resveratrol; Stilbenes; Technology, Pharmaceutical; Temperature | 2007 |
[Study on drug release in vitro and rat intestinal absorption of resveratrol nanoliposomes].
Topics: Administration, Oral; Animals; Delayed-Action Preparations; Drug Compounding; Fallopia japonica; Ileum; Intestinal Absorption; Liposomes; Male; Nanoparticles; Particle Size; Plants, Medicinal; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
Resveratrol suppresses prostate cancer progression in transgenic mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Crosses, Genetic; Disease Progression; Female; Heterozygote; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Prostatic Neoplasms; Resveratrol; Stilbenes | 2007 |
[Comparison of micellar electrokinetic chromatography and microcolumn high performance liquid chromatography for resveratrol analysis].
Topics: Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Resveratrol; Stilbenes | 2007 |
Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation.
Topics: Cell Differentiation; Cell Proliferation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Endoplasmic Reticulum; Enzyme Activation; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Osteocalcin; Resveratrol; RNA, Messenger; Sp7 Transcription Factor; Stilbenes; Transcription Factors | 2007 |
Glucan and resveratrol complex--possible synergistic effects on immune system.
Topics: Animals; Antigens, CD; beta-Glucans; Cytokines; Drug Synergism; Female; Immunologic Factors; Mice; Mice, Inbred BALB C; Phagocytosis; Plant Extracts; Resveratrol; Stilbenes | 2007 |
[Resveratrol and newly synthetized resveratrol analogs in therapy of prostate carcinoma].
Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Humans; Male; Prostatic Neoplasms; Resveratrol; S Phase; Stilbenes; Structure-Activity Relationship; Tumor Stem Cell Assay | 2007 |
Oligomers of resveratrol and ferulic acid prepared by peroxidase-catalyzed oxidation and their protective effects on cardiac injury.
Topics: Animals; Cell Line; Coumaric Acids; Fruit; Heart; Heart Diseases; Momordica charantia; Myocardium; Oxidation-Reduction; Peroxidase; Rats; Resveratrol; Stilbenes | 2007 |
Effects of resveratrol on glycerol-induced renal injury.
Topics: Animals; Antioxidants; Blotting, Western; Glycerol; Heme Oxygenase-1; Immunohistochemistry; Kidney Cortex; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Lymphocytes; Macrophages; Male; Malondialdehyde; NF-kappa B; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tyrosine | 2007 |
Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols.
Topics: Animals; Binding Sites; Cattle; Crystallography, X-Ray; Enzyme Inhibitors; Flavonoids; Models, Molecular; Phenols; Polyphenols; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Proton-Translocating ATPases; Resveratrol; Stilbenes | 2007 |
Effect of resveratrol on baroreceptor activity of carotid sinus in anesthetized male rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Animals; Carotid Sinus; Male; NG-Nitroarginine Methyl Ester; Pressoreceptors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vanadates | 2007 |
[Metabolism of trans-resveratrol-3-O-glucoside in vitro in rat tissues].
Topics: Animals; Duodenum; Female; Gastric Mucosa; Glucosides; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
Protease-activated receptor 4-mediated Ca2+ signaling in mouse lung alveolar epithelial cells.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Estrenes; Gene Expression; Mice; Mice, Inbred C57BL; Oligopeptides; Pulmonary Alveoli; Pyrrolidinones; Receptor, PAR-1; Receptors, Thrombin; Resveratrol; RNA, Messenger; Stilbenes; Thapsigargin; Thrombin | 2007 |
A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens.
Topics: Animals; Biological Assay; Cations, Divalent; Cattle; Cell Line, Tumor; Dose-Response Relationship, Drug; Estrogens; Flavanones; Genistein; Humans; Mutant Proteins; Phytoestrogens; Promoter Regions, Genetic; Receptors, Estrogen; Resveratrol; Stilbenes; Transcription, Genetic; Xenobiotics | 2007 |
Resveratrol, a component of red wine, elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and potassium channels.
Topics: Animals; Antioxidants; Arterioles; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Flavonoids; Guanylate Cyclase; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Potassium Channel Blockers; Potassium Channels; Quinoxalines; Resveratrol; Retinal Artery; Stilbenes; Swine; Vasodilation; Vasodilator Agents; Video Recording; Wine | 2007 |
Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides.
Topics: Animals; Bile; Biological Availability; Glucuronides; Liver; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Perfusion; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfobromophthalein; Taurocholic Acid | 2008 |
[Resveratrol helps restore spermatogenesis after testis injury induced by 2,5-hexanedione].
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Hexanones; Immunohistochemistry; Male; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Seminiferous Epithelium; Spermatogenesis; Stilbenes; Testicular Diseases; Testis | 2007 |
Pomegranate polyphenols and resveratrol protect the neonatal brain against hypoxic-ischemic injury.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Birth Injuries; Calpain; Caspase 3; Caspase Inhibitors; Disease Models, Animal; Enzyme Activation; Female; Flavonoids; Hypoxia-Ischemia, Brain; Lythraceae; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Plant Extracts; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome | 2007 |
In vitro antileishmanial activity of resveratrol and its hydroxylated analogues against Leishmania major promastigotes and amastigotes.
Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Leishmania major; Macrophages; Mice; Resveratrol; Stilbenes | 2007 |
Antiproliferative and pro-apoptotic activity of novel phenolic derivatives of resveratrol.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Cell Membrane; Cell Proliferation; G2 Phase; Humans; Membrane Potentials; Necrosis; Oxidative Stress; Phenols; Reactive Oxygen Species; Resveratrol; Stilbenes; U937 Cells | 2007 |
Pharmacological concentration of resveratrol suppresses aromatase in JEG-3 cells.
Topics: Aromatase; Aromatase Inhibitors; Cell Line; Dose-Response Relationship, Drug; Enzyme Repression; Estrogens; Genes, Reporter; Humans; Luciferases; Placenta; Promoter Regions, Genetic; Recombinant Proteins; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic; Transfection | 2007 |
Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Line, Tumor; Humans; Membrane Potentials; Mice; Mitochondria; Neoplasm Transplantation; Neuroblastoma; Resveratrol; Stilbenes; Transplantation, Heterologous | 2007 |
Resveratrol content in strawberry fruit is affected by preharvest conditions.
Topics: Agriculture; Environment; Fragaria; Fruit; Genotype; Resveratrol; Seeds; Stilbenes | 2007 |
The effect of resveratrol on a cell model of human aging.
Topics: Aging; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p16; Fibroblasts; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Profiling; Humans; Niacinamide; Oligonucleotide Array Sequence Analysis; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Identifying the estrogen receptor coactivator PELP1 in autophagosomes.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Autophagy; Cell Cycle; Cell Proliferation; Co-Repressor Proteins; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lysosomes; Microtubule-Associated Proteins; Models, Biological; Phosphoproteins; Protein Transport; Receptors, Estrogen; Resveratrol; Salivary Gland Neoplasms; Stilbenes; Trans-Activators; Transcription Factors; Tumor Cells, Cultured | 2007 |
Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cellular Senescence; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Male; Oncogene Protein v-akt; Oncogene Proteins; Plant Extracts; Prostatic Neoplasms; Protein Deglycase DJ-1; Protein Processing, Post-Translational; Resveratrol; Seeds; Signal Transduction; Stilbenes; Tumor Cells, Cultured; Vitis | 2007 |
Effects of trans- and cis-resveratrol on Ca2+ handling in A7r5 vascular myocytes.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Blood Vessels; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Fluorescent Dyes; Fura-2; Membrane Potentials; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Rats; Resveratrol; Ryanodine; Stereoisomerism; Stilbenes | 2007 |
Progress curve analysis of CYP1A2 inhibition: a more informative approach to the assessment of mechanism-based inactivation?
Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dihydralazine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Models, Biological; NADP; Paroxetine; Pyrazines; Resveratrol; Stilbenes; Theophylline; Thiones; Thiophenes | 2007 |
Resveratrol sensitizes androgen independent prostate cancer cells to death-receptor mediated apoptosis through multiple mechanisms.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Chromones; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Gene Silencing; Humans; Inhibitor of Apoptosis Proteins; Male; Morpholines; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptors, Death Domain; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Ubiquitin-Protein Ligases | 2007 |
Strong synergistic induction of CYP1A1 expression by andrographolide plus typical CYP1A inducers in mouse hepatocytes.
Topics: Andrographis; Animals; Benz(a)Anthracenes; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Gene Expression Regulation; Hepatocytes; Male; Mice; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits glucose metabolism in human ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Autophagy; Caspases; Cell Growth Processes; Cell Line, Tumor; Deoxyglucose; Female; Glucose; Humans; Ovarian Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Tritium | 2007 |
4-(6-Hydroxy-2-naphthyl)-1,3-bezendiol: a potent, new tyrosinase inhibitor.
Topics: Agaricales; Animals; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroquinones; Kinetics; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Naphthalenes; Naphthols; Phenols; Pyrones; Resorcinols; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits the activity of equine neutrophil myeloperoxidase by a direct interaction with the enzyme.
Topics: Animals; Enzyme Inhibitors; Horses; Neutrophils; Peroxidase; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets.
Topics: Animals; Antioxidants; Arachidonic Acid; Biomarkers; Blood Platelets; Glucaric Acid; Humans; Lipid Peroxidation; Oxidative Stress; Platelet Aggregation; Protein Carbonylation; Rabbits; Resveratrol; Stilbenes; Superoxides; Thrombin | 2008 |
Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Calcium; Calpain; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Mitochondria; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2007 |
Modulation of Sirt1 by resveratrol and nicotinamide alters proliferation and differentiation of pig preadipocytes.
Topics: Adipocytes; Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Forkhead Transcription Factors; Gene Expression Regulation, Developmental; Male; Niacinamide; Resveratrol; RNA, Messenger; Sirtuins; Stilbenes; Swine; Time Factors | 2008 |
Evaluation of different compounds as quorum sensing inhibitors in Pseudomonas aeruginosa.
Topics: Acetylcysteine; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromobacterium; Drug Evaluation, Preclinical; Garlic; Humans; Lincosamides; Macrolides; Plant Extracts; Pseudomonas aeruginosa; Quorum Sensing; Resveratrol; Stilbenes | 2007 |
Inhibitory mechanisms of resveratrol in platelet activation: pivotal roles of p38 MAPK and NO/cyclic GMP.
Topics: Animals; Calcium; Collagen; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Mice; Nitrates; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositols; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Resveratrol; Stilbenes; Thromboxane A2 | 2007 |
Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells.
Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leukemia-Lymphoma, Adult T-Cell; Lithium Chloride; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phytoalexins; Proto-Oncogene Proteins c-akt; Receptors, Notch; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Signal Transduction; Stilbenes; Terpenes; Time Factors; Tumor Suppressor Protein p53 | 2007 |
Stabilization and encapsulation of photosensitive resveratrol within yeast cell.
Topics: Biological Availability; Biphenyl Compounds; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Compounding; Drug Stability; Drug Storage; Free Radical Scavengers; Hot Temperature; Light; Microscopy, Confocal; Microscopy, Fluorescence; Particle Size; Picrates; Powders; Resveratrol; Saccharomyces cerevisiae; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2008 |
Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor.
Topics: Animals; Apoptosis; Encephalomyelitis, Autoimmune, Experimental; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Resveratrol; Stilbenes; T-Lymphocyte Subsets | 2007 |
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.
Topics: Adenylate Kinase; Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Drosophila melanogaster; Humans; Longevity; Male; Metabolic Detoxication, Phase II; Resveratrol; Sirtuins; Stilbenes | 2007 |
Effects of resveratrol (trans-3,5,4'-trihydroxystilbene) treatment on cardiac remodeling following myocardial infarction.
Topics: Animals; Cardiotonic Agents; Echocardiography; Hemodynamics; Male; Myocardial Infarction; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Ventricular Remodeling | 2007 |
[Effect of different light intensity on Polygonum cuspidatum callus].
Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Light; Plant Leaves; Plant Stems; Plants, Medicinal; Resveratrol; Stilbenes; Tissue Culture Techniques | 2007 |
[Roles of potassium channel in effects of resveratrol on isolated myocardial contractility and heart rate research in guinea pig].
Topics: Animals; Barium Compounds; Cardiotonic Agents; Chlorides; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Heart Rate; In Vitro Techniques; KATP Channels; Male; Myocardial Contraction; Plants, Medicinal; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Potassium Channels, Inwardly Rectifying; Resveratrol; Stilbenes; Tetraethylammonium | 2007 |
Resveratrol induces catalytic bioscavenger paraoxonase 1 expression and protects against chemical warfare nerve agent toxicity in human cell lines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryldialkylphosphatase; Butyrylcholinesterase; Cell Line; Chemical Warfare Agents; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Mice; Resveratrol; Sarin; Soman; Stilbenes | 2008 |
Effects of resveratrol on number and activity of endothelial progenitor cells from human peripheral blood.
Topics: Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; G1 Phase; Humans; Neovascularization, Physiologic; Phytoestrogens; Resting Phase, Cell Cycle; Resveratrol; S Phase; Stem Cells; Stilbenes; Time Factors; Vascular Endothelial Growth Factor A | 2007 |
Occurrence of resveratrol and piceid in American and European hop cones.
Topics: Chromatography, High Pressure Liquid; Europe; Glucosides; Humulus; Mass Spectrometry; Resveratrol; Species Specificity; Stilbenes; Time Factors; United States | 2007 |
SIRT1 is involved in glucocorticoid-mediated control of uncoupling protein-3 gene transcription.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Fatty Acids; Glucocorticoids; Ion Channels; Male; Membrane Potential, Mitochondrial; Mice; Mitochondrial Proteins; Muscle Proteins; Muscle, Skeletal; MyoD Protein; Oxidation-Reduction; p300-CBP Transcription Factors; Protein Processing, Post-Translational; Rats; Reactive Oxygen Species; Receptors, Glucocorticoid; Repressor Proteins; Response Elements; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic; Uncoupling Protein 3 | 2007 |
Bax-inhibiting peptide protects cells from polyglutamine toxicity caused by Ku70 acetylation.
Topics: Acetylation; Animals; Antigens, Nuclear; bcl-2-Associated X Protein; Caspases; Cell Death; Cell Line; Cyclic AMP Response Element-Binding Protein; Cytoprotection; DNA Fragmentation; DNA-Binding Proteins; Histone Acetyltransferases; Humans; Ku Autoantigen; Mutant Proteins; Peptides; Protein Binding; Protein Conformation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vacuoles | 2007 |
Effects of resveratrol, a grape polyphenol, on catecholamine secretion and synthesis in cultured bovine adrenal medullary cells.
Topics: Acetylcholine; Adrenal Medulla; Animals; Antioxidants; Calcium; Catecholamines; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Female; Flavonoids; Histamine; Ion Transport; Membrane Potentials; omega-Agatoxin IVA; omega-Conotoxin GVIA; Oocytes; Phenols; Polyphenols; Potassium; Receptors, Nicotinic; Resveratrol; Sodium; Stilbenes; Tyrosine; Veratridine; Vitis; Xenopus | 2007 |
Total synthesis of resveratrol-based natural products: a chemoselective solution.
Topics: Biological Products; Resveratrol; Stilbenes | 2007 |
Genomics: vine work.
Topics: Genes, Plant; Genome, Plant; Genomics; Plant Diseases; Resveratrol; Sequence Analysis, DNA; Stilbenes; Vitis; Wine | 2007 |
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B.
Topics: Animals; Chromatin; Down-Regulation; Gene Expression Regulation; Insulin; Insulin Resistance; Mice; Mice, Knockout; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Cytidine; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2007 |
Evaluation of resveratrol and piceatannol cytotoxicity in macrophages, T cells, and skin cells.
Topics: Animals; Antioxidants; Cell Proliferation; Cell Survival; Glutathione; Humans; Lipid Peroxidation; Macrophages; Mice; Resveratrol; Skin; Stilbenes; T-Lymphocytes; Tumor Cells, Cultured | 2007 |
Resveratrol induces pro-apoptotic endoplasmic reticulum stress in human colon cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspases; Colonic Neoplasms; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Eukaryotic Initiation Factor-2; Flow Cytometry; Heat-Shock Proteins; HT29 Cells; Humans; Molecular Chaperones; Nuclear Proteins; Phosphorylation; Regulatory Factor X Transcription Factors; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1 | 2007 |
Pretreatment effect of resveratrol on streptozotocin-induced diabetes in rats.
Topics: Animals; Antioxidants; Catalase; Copper; Diabetes Mellitus, Experimental; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin; Zinc | 2007 |
Resveratrol: is there any effect on healthy subject?
Topics: Animals; Antioxidants; Catalase; Copper; Diabetes Mellitus, Experimental; Humans; Male; Malondialdehyde; Nitric Oxide; Nitrogen; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Zinc | 2007 |
Resveratrol tetramers with a C6-C3 or a C1 unit from Upuna borneensis.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Dipterocarpaceae; Flavonoids; Molecular Structure; Phenols; Plant Stems; Polyphenols; Resveratrol; Spectrum Analysis; Stilbenes | 2007 |
Hypoxia enhances LPA-induced HIF-1alpha and VEGF expression: their inhibition by resveratrol.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lysophospholipids; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Stilbenes; Transfection; Vascular Endothelial Growth Factor A | 2007 |
Enteral resveratrol supplementation attenuates intestinal epithelial inducible nitric oxide synthase activity and mucosal damage in experimental necrotizing enterocolitis.
Topics: Administration, Oral; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Enterocolitis, Necrotizing; Female; Ileum; Intestinal Mucosa; Male; Microvilli; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Pregnancy; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
Changes in the phytochemical composition and profile of raw, boiled, and roasted peanuts.
Topics: Arachis; Flavonoids; Food Handling; Genistein; Hot Temperature; Phenols; Polyphenols; Resveratrol; Seeds; Stilbenes | 2007 |
Changing of antioxidant enzyme activity on the biliary obstructed rats treated with resveratrol.
Topics: Animals; Antioxidants; Bile Ducts; Bilirubin; Cholestasis; Erythrocytes; Ligation; Liver; Male; Nitric Oxide; Oxidoreductases; Rats; Resveratrol; Stilbenes | 2007 |
Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia.
Topics: Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Down-Regulation; Encephalitis; Free Radical Scavengers; Free Radicals; Gliosis; Inflammation Mediators; Lipopolysaccharides; Microglia; Oxidative Stress; Rats; Resveratrol; Stilbenes | 2007 |
Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation.
Topics: Animals; Apoptosis; Cell Line; Coculture Techniques; Flavonoids; Fluorescent Antibody Technique; Gene Expression; In Situ Nick-End Labeling; Inflammation; Interleukin-1alpha; Lipopolysaccharides; Microglia; Neurons; Neuroprotective Agents; Phenols; Polyphenols; Quercetin; Rats; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2008 |
Resveratrol modulates roscovitine-mediated cell cycle arrest of human MCF-7 breast cancer cells.
Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA; Female; Flow Cytometry; Humans; Purines; Resveratrol; Roscovitine; Stilbenes | 2008 |
Antimyeloma effects of resveratrol through inhibition of angiogenesis.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Proliferation; Fibroblast Growth Factor 2; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Multiple Myeloma; Resveratrol; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A | 2007 |
The dietary antioxidants resveratrol and quercetin protect cells from exogenous pro-oxidative damage.
Topics: Antioxidants; Cell Count; Cell Division; Cell Line, Tumor; Cell Survival; Diet; Dinoprostone; HT29 Cells; Humans; Hydrogen Peroxide; Oxidants; Oxidative Stress; Quercetin; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes; Vascular Endothelial Growth Factor A | 2008 |
Resveratrol modulates phagocytosis of bacteria through an NF-kappaB-dependent gene program.
Topics: Animals; Cell Line; Escherichia coli; Gene Expression Regulation; Humans; Macrophages; Mice; NF-kappa B; Phagocytosis; Receptors, Immunologic; Resveratrol; Staphylococcus aureus; Stilbenes; Toll-Like Receptor 2 | 2008 |
The effect of resveratrol on prevention of the development of postoperative adhesions in a rat model.
Topics: Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Postoperative Complications; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Tissue Adhesions | 2007 |
[Study on the stability of resveratrol in rhizoma polygoni cuspidati].
Topics: Antineoplastic Agents, Phytogenic; Drug Stability; Drugs, Chinese Herbal; Fallopia japonica; Hot Temperature; Hydrogen-Ion Concentration; Plants, Medicinal; Resveratrol; Solvents; Spectrophotometry, Ultraviolet; Stilbenes | 2007 |
Protective effects of resveratrol on ethanol-induced apoptosis in embryonic stem cells and disruption of embryonic development in mouse blastocysts.
Topics: Animals; Antioxidants; Apoptosis; Blastocyst; Calcium; Caspase 3; Caspase 9; Cell Line; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryonic Development; Embryonic Stem Cells; Enzyme Activation; Ethanol; Female; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Mitochondria; Nitric Oxide; p21-Activated Kinases; Pregnancy; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors; Up-Regulation | 2007 |
Effect of resveratrol on 17beta-estradiol sulfation by human hepatic and jejunal S9 and recombinant sulfotransferase 1E1.
Topics: Arylsulfotransferase; Estradiol; Female; Humans; Jejunum; Liver; Male; Microsomes; Microsomes, Liver; Phytoestrogens; Recombinant Proteins; Resveratrol; Stilbenes; Sulfates; Sulfotransferases | 2008 |
Comparison of the contents of various antioxidants of sea buckthorn berries using CE.
Topics: Antioxidants; Ascorbic Acid; Catechin; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Estonia; Flavonoids; Fruit; Hippophae; Quercetin; Resveratrol; Stilbenes | 2007 |
Resveratrol induces the heat-shock response and protects human cells from severe heat stress.
Topics: Cell Line; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Molecular Chaperones; Oxidative Stress; Promoter Regions, Genetic; Resveratrol; Stilbenes; Tunicamycin | 2008 |
Inhibition of caspases and intracellular free Ca2+ concentrations are involved in resveratrol protection against apoptosis in rat primary neuron cultures.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Calcium; Caspase Inhibitors; Caspases; Cell Culture Techniques; Cerebral Cortex; Intracellular Fluid; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2007 |
Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Cell Proliferation; Cells, Cultured; Chondrocytes; Humans; Interleukin-1beta; Poly(ADP-ribose) Polymerases; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2008 |
Induction of full-length survival motor neuron by polyphenol botanical compounds.
Topics: Alternative Splicing; Catechin; Cells, Cultured; Curcumin; Cyclic AMP Response Element-Binding Protein; Exons; Flavonoids; Humans; Models, Biological; Nerve Tissue Proteins; Phenols; Plants; Polyphenols; Resveratrol; RNA Precursors; RNA-Binding Proteins; SMN Complex Proteins; Stilbenes; Survival of Motor Neuron 1 Protein; Survival of Motor Neuron 2 Protein; Up-Regulation | 2008 |
Resveratrol inhibits TNF-alpha-induced changes of adipokines in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Interleukin-6; Mice; Resveratrol; Serpin E2; Serpins; Stilbenes; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2007 |
Immortalization of epithelial progenitor cells mediated by resveratrol.
Topics: Adult; Cell Separation; Cell Survival; Cells, Cultured; Enzyme Activation; Epithelial Cells; Female; Humans; Progesterone; Receptors, Estrogen; Resveratrol; Stem Cells; Stilbenes; Telomerase | 2008 |
[Effect of resveratrol on heart function of rats with adriamycin-induced heart failure].
Topics: Animals; Doxorubicin; Heart; Heart Failure; Male; Malondialdehyde; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2007 |
Piceatannol inhibits melanogenesis by its antioxidative actions.
Topics: Animals; Antioxidants; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Glutathione; Glutathione Disulfide; Inhibitory Concentration 50; Melanins; Melanocytes; Melanoma, Experimental; Mice; Molecular Structure; Monophenol Monooxygenase; Pyrones; Reactive Oxygen Species; Resveratrol; Stilbenes | 2007 |
Effects of resveratrol on skeletal muscle in ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Hindlimb; Injections, Intraperitoneal; Male; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2007 |
Resveratrol is pro-apoptotic and thyroid hormone is anti-apoptotic in glioma cells: both actions are integrin and ERK mediated.
Topics: Apoptosis; Brain Neoplasms; Cyclooxygenase 2; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glioma; Humans; Integrin alphaVbeta3; Phosphorylation; Protein Kinase C; Resveratrol; Stilbenes; Thyroxine | 2008 |
Effect of low doses of red wine and pure resveratrol on circulating endothelial progenitor cells.
Topics: Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Stem Cells; Stilbenes; Tumor Necrosis Factor-alpha; Wine | 2008 |
Playng defense against Lou Gehrig's disease.
Topics: Amyotrophic Lateral Sclerosis; Animals; Axons; Brain; Cell Death; Exercise; Humans; Male; Motor Neurons; Nerve Degeneration; Nerve Growth Factors; Resveratrol; RNA Interference; Spinal Cord; Stem Cell Transplantation; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2007 |
Resveratrol (trans-resveratrol, 3,5,4'-trihydroxy-trans-stilbene) glucuronidation exhibits atypical enzyme kinetics in various protein sources.
Topics: Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Microsomes; Recombinant Proteins; Resveratrol; Stilbenes | 2008 |
Melanoma vasculogenic mimicry is strongly related to reactive oxygen species level.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Capillaries; Caspase 3; Cell Line, Tumor; Cytochromes c; Female; Humans; Melanoma; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Reactive Oxygen Species; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2007 |
Comparative studies of the antioxidant effects of a naturally occurring resveratrol analogue -- trans-3,3',5,5'-tetrahydroxy-4'-methoxystilbene and resveratrol -- against oxidation and nitration of biomolecules in blood platelets.
Topics: Adult; Antioxidants; Blood Platelets; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Glutathione; Humans; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Plant Bark; Protein Carbonylation; Resveratrol; Stilbenes; Sulfhydryl Compounds; Yucca | 2008 |
[Effects of resveratrol on inflammatory process induced by focal cerebral ischemia-reperfusion in rats].
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Neuroprotective Agents; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2007 |
Optimization of trans-resveratrol concentration and sensory properties of peanut kernels by slicing and ultrasound treatment, using response surface methodology.
Topics: Antioxidants; Arachis; Consumer Behavior; Food Handling; Food Technology; Nutritive Value; Odorants; Particle Size; Resveratrol; Stilbenes; Taste; Time Factors; Ultrasonics | 2007 |
Delivery of cytoplasmic proteins to autophagosomes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Cell Line, Tumor; Co-Repressor Proteins; Cytoplasm; Endosomal Sorting Complexes Required for Transport; Estrogen Receptor beta; Humans; Microtubule-Associated Proteins; Phagosomes; Phosphoproteins; Protein Transport; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators; Transcription Factors | 2008 |
Evaluation of antitumor effects of two vine stalk oligomers of resveratrol on a panel of lymphoid and myeloid cell lines: comparison with resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Enzyme Activation; fas Receptor; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Membrane Potentials; Mitochondrial Membranes; Plants; Resveratrol; Stilbenes | 2007 |
High performance liquid chromatographic method for the determination and pharmacokinetic studies of oxyresveratrol and resveratrol in rat plasma after oral administration of Smilax china extract.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Molecular Structure; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Resveratrol; Smilax; Stilbenes | 2008 |
Molecular mechanisms of p21 and p27 induction by 3-methylcholanthrene, an aryl-hydrocarbon receptor agonist, involved in antiproliferation of human umbilical vascular endothelial cells.
Topics: Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Gene Expression Regulation; Humans; Luciferases; Methylcholanthrene; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Receptors, Aryl Hydrocarbon; Response Elements; Resveratrol; Sequence Deletion; Stilbenes; Time Factors; Tritium; Umbilical Cord | 2008 |
Detection, characterization, and quantification of resveratrol glycosides in transgenic arabidopsis over-expressing a sorghum stilbene synthase gene by liquid chromatography/tandem mass spectrometry.
Topics: Acyltransferases; Arabidopsis; Chromatography, High Pressure Liquid; DNA, Plant; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glycosides; Glycosylation; Plant Extracts; Plants, Genetically Modified; Resveratrol; Sorghum; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2007 |
Clusterin mediates TRAIL resistance in prostate tumor cells.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Clusterin; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Janus Kinases; Male; Prostatic Neoplasms; Proto-Oncogene Proteins pp60(c-src); Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; RNA, Small Interfering; STAT Transcription Factors; Stilbenes; Taxoids; TNF-Related Apoptosis-Inducing Ligand | 2007 |
Resveratrol attenuates cisplatin-induced nephrotoxicity in rats.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Creatinine; Drug Therapy, Combination; Ectodysplasins; Kidney Tubular Necrosis, Acute; Kidney Tubules; Macrophages; Male; Monocytes; Proteinuria; Rats; Rats, Wistar; Resveratrol; Stilbenes; T-Lymphocytes; Urination | 2008 |
Resveratrol potentiates genistein's antiadipogenic and proapoptotic effects in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Genistein; Lipid Metabolism; Lipolysis; Mice; Mitogen-Activated Protein Kinases; PPAR gamma; Resveratrol; Stilbenes | 2007 |
Effects of resveratrol on calcium regulation in rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Male; Organ Size; Pancreatitis; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Severity of Illness Index; Stilbenes; Taurocholic Acid; Time Factors | 2008 |
Effect of winemaking practices on color indexes and selected bioactive phenolics of Aglianico wine.
Topics: Adult; Anthocyanins; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Color; Food Handling; Food Technology; Humans; Italy; Pectins; Phenols; Quercetin; Resveratrol; Rutin; Stilbenes; Sulfur Dioxide; Taste; Time Factors; Viscosity; Vitis; Wine | 2007 |
Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri.
Topics: Animals; Anticarcinogenic Agents; Apoptosis Regulatory Proteins; Cell Death; Female; Humans; Maternal Exposure; Neuropeptides; Ovarian Follicle; Polycyclic Aromatic Hydrocarbons; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Aryl Hydrocarbon; Resveratrol; Smoking; Stilbenes; Tobacco Smoke Pollution; Transplantation, Heterologous | 2007 |
Redox regulation of resveratrol-mediated switching of death signal into survival signal.
Topics: Animals; Cardiotonic Agents; Cell Death; Cell Survival; Cisplatin; Drug Antagonism; Genes, bcl-2; Male; Mice; Mice, Transgenic; Myocardial Reperfusion Injury; Myocytes, Cardiac; NADH, NADPH Oxidoreductases; Organ Specificity; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Resveratrol; RNA, Antisense; Signal Transduction; Stilbenes; Thioredoxins | 2008 |
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Topics: Acetylation; Allosteric Site; Animals; Blood Glucose; Caloric Restriction; Catalytic Domain; Cell Line; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Drosophila melanogaster; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin; Male; Mice; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Zucker; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2007 |
Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Enzyme Inhibitors; Epigenesis, Genetic; Gene Silencing; Genes, Dominant; Humans; Lipid Metabolism; Lysosomes; Phagosomes; Phosphatidylinositol 3-Kinases; Phosphotransferases; Resveratrol; Stilbenes | 2008 |
[Increasing the content of active constituents in Polygonum cuspidatum hairy root by gene transformation technology].
Topics: Acyltransferases; DNA Primers; DNA, Plant; Drugs, Chinese Herbal; Fallopia japonica; Genetic Vectors; Glucosides; Molecular Sequence Data; Plant Roots; Plants, Genetically Modified; Plants, Medicinal; Resveratrol; Rhizobium; Stilbenes; Transformation, Genetic | 2007 |
Candicidal action of resveratrol isolated from grapes on human pathogenic yeast C. albicans.
Topics: Antifungal Agents; Candida albicans; Cell Cycle; Cytosol; Erythrocytes; Humans; Microbial Viability; Mycelium; Resveratrol; Stilbenes; Trehalose; Vitis | 2007 |
Resveratrol inhibits the secretion of vascular endothelial growth factor and subsequent proliferation in human leukemia U937 cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; Stilbenes; U937 Cells; Vascular Endothelial Growth Factor A | 2007 |
Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Blood Pressure; Electrocardiography; Endothelin-1; Glucose Transporter Type 4; Heart Rate; In Situ Nick-End Labeling; In Vitro Techniques; Insulin; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Obesity; Rats; Rats, Zucker; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Interaction of beta-lactoglobulin with resveratrol and its biological implications.
Topics: Biological Availability; Circular Dichroism; Lactoglobulins; Protein Structure, Secondary; Protein Structure, Tertiary; Resveratrol; Solubility; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stilbenes | 2008 |
Isocratic chromatography of resveratrol and piceid after previous generation of fluorescent photoproducts: wine analysis without sample preparation.
Topics: Chromatography, Liquid; Fluorescent Dyes; Glucosides; Isomerism; Molecular Structure; Resveratrol; Stilbenes; Surface Properties; Wine | 2007 |
Effect of resveratrol, tyrosol and beta-sitosterol on oxidised low-density lipoprotein-stimulated oxidative stress, arachidonic acid release and prostaglandin E2 synthesis by RAW 264.7 macrophages.
Topics: Animals; Antioxidants; Arachidonic Acid; Atherosclerosis; Cells, Cultured; Dinoprostone; Hydrogen Peroxide; Lipid Metabolism; Lipoproteins, LDL; Macrophages; Mice; Olive Oil; Oxidative Stress; Phenylethyl Alcohol; Plant Oils; Protein Binding; Resveratrol; Sitosterols; Stilbenes; Wine | 2008 |
Metabolism of resveratrol in breast cancer cell lines: impact of sulfotransferase 1A1 expression on cell growth inhibition.
Topics: Antineoplastic Agents, Phytogenic; Arylsulfotransferase; Breast Neoplasms; Cell Proliferation; Chromatography, High Pressure Liquid; Chromatography, Liquid; DNA Primers; Female; Gene Expression Regulation, Enzymologic; Growth Inhibitors; Humans; Mass Spectrometry; Neoplasms, Hormone-Dependent; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2008 |
Optimization and validation of a chromatographic method for the simultaneous quantification of six bioactive compounds in Rhizoma et Radix Polygoni Cuspidati.
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Molecular Structure; Reproducibility of Results; Resveratrol; Rhizome; Stilbenes; Technology, Pharmaceutical | 2008 |
Molecular mechanisms of resveratrol action in lung cancer cells using dual protein and microarray analyses.
Topics: Anticarcinogenic Agents; Carcinoma; Cell Cycle; Cell Division; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2007 |
Chemoprotective action of resveratrol and genistein from apoptosis induced in human peripheral blood lymphocytes.
Topics: Adult; Anticarcinogenic Agents; Antimutagenic Agents; Apoptosis; Cell Separation; Flow Cytometry; Genistein; Humans; Lymphocytes; Resveratrol; Stilbenes | 2008 |
Analgesic resveratrol?
Topics: Analgesics; Animals; Cyclooxygenase Inhibitors; Rats; Resveratrol; Stilbenes | 2008 |
Concentrations of resveratrol and derivatives in foods and estimation of dietary intake in a Spanish population: European Prospective Investigation into Cancer and Nutrition (EPIC)-Spain cohort.
Topics: Adult; Age Factors; Aged; Cohort Studies; Databases, Factual; Diet, Mediterranean; Feeding Behavior; Female; Food Analysis; Glucosides; Humans; Male; Middle Aged; Resveratrol; Sex Factors; Spain; Stilbenes; Wine | 2008 |
A pilot study of evaluation of the antioxidative activity of resveratrol and its analogue in a 6-month feeding test in young adult mice.
Topics: Animals; Antioxidants; Body Weight; Diet; Feeding Behavior; Female; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Micronucleus Tests; Pilot Projects; Resveratrol; Stilbenes | 2008 |
Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
Topics: Acetylation; Adenoviridae; Animals; Blotting, Western; Cell Line, Tumor; Early Growth Response Protein 1; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genetic Therapy; Humans; Mice; Mice, Nude; Rats; Resveratrol; Sirtuins; Stilbenes; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2008 |
The protective effect of resveratrol on the intestinal mucosal barrier in rats with severe acute pancreatitis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Endotoxins; Intestinal Mucosa; Male; Pancreas; Pancreatitis; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
[Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].
Topics: Anthraquinones; Ecosystem; Emodin; Fertilizers; Glucosides; Nitrogen; Phosphorus; Plant Roots; Plants, Medicinal; Potassium; Regression Analysis; Resveratrol; Rumex; Soil; Stilbenes | 2007 |
Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.
Topics: Antioxidants; Cells, Cultured; Down-Regulation; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Lung; NF-E2-Related Factor 2; Oxidative Stress; Protein Transport; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Smoking; Stilbenes | 2008 |
Fate of resveratrol and piceid through different hop processings and storage times.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Food Handling; Glucosides; Humulus; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2008 |
Resveratrol reverses hydrogen peroxide-induced proliferative effects in human coronary smooth muscle cells: a novel signaling mechanism.
Topics: Antioxidants; Cell Line; Cell Proliferation; Coronary Vessels; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Oxidants; Protein Kinase Inhibitors; Resveratrol; Stilbenes | 2008 |
Resveratrol-induced apoptosis in human breast cancer cells is mediated primarily through the caspase-3-dependent pathway.
Topics: Antioxidants; Apoptosis; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Female; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Resveratrol; Stilbenes | 2008 |
Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol Ester Transfer Proteins; Cricetinae; Dietary Fats; Enzyme Inhibitors; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Lipids; Liver; Male; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors; Triglycerides | 2008 |
Effect of grape polyphenols on oxidative stress in canine lens epithelial cells.
Topics: Animals; Cells, Cultured; Dogs; Epithelial Cells; Free Radical Scavengers; Grape Seed Extract; Lens, Crystalline; Oxidative Stress; Plant Extracts; Proanthocyanidins; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD.
Topics: Antioxidants; Cell Line; Deoxyribonuclease (Pyrimidine Dimer); Dose-Response Relationship, Drug; Escherichia coli Proteins; Fibroblasts; Humans; Oxidative Stress; Resveratrol; Stilbenes; Superoxide Dismutase; Up-Regulation | 2008 |
Resveratrol modulates DNA double-strand break repair pathways in an ATM/ATR-p53- and -Nbs1-dependent manner.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cell Line; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Nuclear Proteins; Protein Serine-Threonine Kinases; Recombination, Genetic; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2008 |
Take a break--resveratrol in action on DNA.
Topics: Animals; Antioxidants; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; DNA Damage; DNA Repair; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genome; Humans; Models, Biological; Neoplasms; Protein Serine-Threonine Kinases; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Proteins | 2008 |
Resveratrol ameliorates Serratia marcescens-induced acute pneumonia in rats.
Topics: Animals; Cytokines; Dexamethasone; Male; NF-kappa B; Phagocytosis; Pneumonia, Bacterial; Rats; Rats, Sprague-Dawley; Resveratrol; Serratia Infections; Serratia marcescens; Stilbenes; Trachea | 2008 |
Effect of methyl substitution on the antioxidative property and genotoxicity of resveratrol.
Topics: Animals; Antioxidants; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Methylation; Mutagens; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Silencing metabolic disorders by novel SIRT1 activators.
Topics: Animals; Antioxidants; Humans; Metabolic Diseases; Models, Biological; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2008 |
Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Topics: Animals; Antioxidants; Antithyroid Agents; Blotting, Western; Cardiomegaly; Cell Size; Cells, Cultured; Densitometry; Diet; Enzyme Activation; Fibrosis; Fructose; Male; Mice; Mice, Transgenic; Myocardium; Myosin Heavy Chains; NAD; Nutritional Physiological Phenomena; Propylthiouracil; Resveratrol; RNA; Sirtuin 1; Sirtuins; Stilbenes; Transfection | 2008 |
SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.
Topics: Animals; Benzamides; Brain; Histone Deacetylase 1; Histone Deacetylases; Homeodomain Proteins; Humans; Immunoprecipitation; Inhibitor of Growth Protein 1; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Naphthols; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Repressor Proteins; Resveratrol; Retinol-Binding Proteins, Cellular; Sin3 Histone Deacetylase and Corepressor Complex; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2008 |
RETRACTED: Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Carcinogens; Chemoprevention; Cytochromes c; Disease Models, Animal; In Situ Nick-End Labeling; Male; Mice; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
Resveratrol down-regulates the androgen receptor at the post-translational level in prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Protein Processing, Post-Translational; Receptors, Androgen; Resveratrol; Stilbenes | 2007 |
Neuroprotective effect of Smilacis chinae rhizome on NMDA-induced neurotoxicity in vitro and focal cerebral ischemia in vivo.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Infarction, Middle Cerebral Artery; Male; N-Methylaspartate; Neurons; Neuroprotective Agents; Plant Extracts; Plant Preparations; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Rhizome; Smilax; Stilbenes; Time Factors | 2008 |
Protective effects of resveratrol on UVB-irradiated HaCaT cells through attenuation of the caspase pathway.
Topics: Antioxidants; Apoptosis; Caspase Inhibitors; Cell Line; Cell Proliferation; Cytoprotection; Humans; Reactive Oxygen Species; Resveratrol; Stilbenes; Sunscreening Agents; Ultraviolet Rays | 2008 |
The insulin-suppressive effect of resveratrol - an in vitro and in vivo phenomenon.
Topics: Acetylcholine; Animals; Antioxidants; Dose-Response Relationship, Drug; Drug Antagonism; Drug Combinations; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Culture Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, Somatostatin; Resveratrol; Stilbenes; Succinic Acid | 2008 |
The effects of resveratrol on vasospasm after experimental subarachnoidal hemorrhage in rats.
Topics: Animals; Antioxidants; Basilar Artery; Endothelin-1; Injections, Intravenous; Lipid Peroxidation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Resveratrol; Stilbenes; Subarachnoid Hemorrhage; Superoxide Dismutase; Vasodilation; Vasospasm, Intracranial; Vertebrobasilar Insufficiency | 2008 |
Conjugation of resveratrol with RGD and KGD derivatives.
Topics: Catalysis; Chromatography, High Pressure Liquid; Dicyclohexylcarbodiimide; Esterification; Humans; Lysine; Oligopeptides; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2007 |
Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Gene Expression Regulation; Humans; Melanoma; NF-kappa B; Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; STAT3 Transcription Factor; Stilbenes; TNF-Related Apoptosis-Inducing Ligand | 2008 |
If you have your wine, can you eat your cake too?
Topics: Animals; Antioxidants; Dietary Fats; Dietary Supplements; Humans; Mice; Middle Aged; Resveratrol; Stilbenes; Wine | 2007 |
Comparative anti-platelet and antioxidant properties of polyphenol-rich extracts from: berries of Aronia melanocarpa, seeds of grape and bark of Yucca schidigera in vitro.
Topics: Adult; Antioxidants; Blood Platelets; Collagen; Female; Flavonoids; Hemostatics; Humans; Male; Phenols; Photinia; Plant Bark; Plant Extracts; Platelet Activation; Platelet Aggregation Inhibitors; Polyphenols; Resveratrol; Seeds; Stilbenes; Superoxides; Thrombin; Vitis; Yucca | 2008 |
Involvement of mammalian sirtuin 1 in the action of ethanol in the liver.
Topics: Acetylation; Alcohol Drinking; Animals; Cell Line, Tumor; Disease Models, Animal; Down-Regulation; Enzyme Activators; Ethanol; Fatty Liver, Alcoholic; Gene Expression Regulation, Enzymologic; Glycerol-3-Phosphate O-Acyltransferase; Lipogenesis; Liver; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Resveratrol; RNA Interference; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 1; Stilbenes; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection | 2008 |
Effect of antioxidants pQ510 and resveratrol on regulatory function of the endothelium in rats with modeled arterial hypertension.
Topics: Animals; Antioxidants; Ascorbic Acid; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organometallic Compounds; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2007 |
A possible link between resveratrol and TGF-beta: resveratrol induction of TGF-beta expression and signaling.
Topics: Autocrine Communication; Cell Line, Tumor; Epithelial Cells; Gene Expression Regulation; Humans; Kinetics; Lung; Phosphorylation; Promoter Regions, Genetic; Receptors, Estrogen; Resveratrol; RNA, Messenger; Signal Transduction; Smad3 Protein; Stilbenes; Transforming Growth Factor beta2 | 2008 |
Imatinib mesylate-resistant human chronic myelogenous leukemia cell lines exhibit high sensitivity to the phytoalexin resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Caspases; Cell Differentiation; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Pyrimidines; Resveratrol; Stilbenes | 2008 |
Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Transformation, Neoplastic; Cells, Cultured; MAP Kinase Kinase 1; Mice; NF-kappa B; Proto-Oncogene Proteins c-raf; Quercetin; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Wine | 2008 |
Protective effect of resveratrol against naphthalene-induced oxidative stress in mice.
Topics: Animals; Antioxidants; Environmental Pollutants; Female; Glutathione; Kidney; Liver; Lung; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Naphthalenes; Neutrophils; Oxidative Stress; Resveratrol; Stilbenes | 2008 |
Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium.
Topics: AMP-Activated Protein Kinases; Animals; Biological Transport, Active; Blood Glucose; Caveolae; Caveolin 1; Caveolin 3; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Immunohistochemistry; In Vitro Techniques; Male; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARalpha.
Topics: Animals; Cell Line, Tumor; Drug Design; Ligands; Models, Molecular; Molecular Structure; PPAR alpha; Protein Binding; Rats; Resveratrol; Stilbenes | 2008 |
Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin B.
Topics: Apoptosis; Aurovertins; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Membrane Proteins; Mitochondrial Proton-Translocating ATPases; Models, Molecular; Resveratrol; Stilbenes; Up-Regulation | 2008 |
Caspase-8 has an essential role in resveratrol-induced apoptosis of rheumatoid fibroblast-like synoviocytes.
Topics: Apoptosis; Apoptosis Inducing Factor; Arthritis, Rheumatoid; Caspase 8; Cells, Cultured; Fibroblasts; Fluorescent Antibody Technique; Humans; Membrane Potentials; Mitochondria; Probability; Resveratrol; Sensitivity and Specificity; Stilbenes; Synovial Membrane | 2008 |
trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Genitalia, Male; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Relaxation; Muscle, Smooth; No-Observed-Adverse-Effect Level; Organ Size; Penile Erection; Rabbits; Resveratrol; Sperm Count; Sperm Motility; Spermatozoa; Stilbenes; Testis; Testosterone | 2008 |
Resveratrol attenuates hepatic injury after trauma-hemorrhage via estrogen receptor-related pathway.
Topics: Animals; Antioxidants; Chemokine CXCL1; Chemokines, CXC; Estradiol; Fulvestrant; Hemorrhage; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-6; Liver; Male; Rats; Receptors, Estrogen; Resveratrol; Shock, Hemorrhagic; Stilbenes | 2008 |
Brain transcriptomics in response to beta-naphthoflavone treatment in rainbow trout: the role of aryl hydrocarbon receptor signaling.
Topics: Animals; beta-Naphthoflavone; Brain; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation; Gonadal Steroid Hormones; Neurosecretory Systems; Oligonucleotide Array Sequence Analysis; Oncorhynchus mykiss; Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Stress, Physiological | 2008 |
Resveratrol attenuates inflammation and stricture formation in experimental caustic esophageal burns.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns, Chemical; Caustics; Collagen; Disease Models, Animal; Esophageal Stenosis; Esophagitis; Glutathione; Inflammation; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Research Design; Resveratrol; Stilbenes | 2008 |
Resveratrol analog trans 3,4,5,4'-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Biopolymers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Estrogens; Female; Humans; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Resveratrol; STAT3 Transcription Factor; Stilbenes; Tubulin | 2008 |
Resveratrol and X rays affect gap junction intercellular communications in human glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Communication; Cell Cycle; Cell Line, Tumor; Cell Survival; Connexin 43; Gap Junctions; Glioblastoma; Humans; Microscopy, Fluorescence; Mutation; Resveratrol; Stilbenes; X-Rays | 2008 |
Stilbene analogues affect cell cycle progression and apoptosis independently of each other in an MCF-7 array of clones with distinct genetic and chemoresistant backgrounds.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Proliferation; Clone Cells; Drug Resistance, Neoplasm; Female; Genes, erbB-2; Genes, p53; Humans; Resveratrol; Stilbenes | 2008 |
Anti-cancer effect of resveratrol is associated with induction of apoptosis via a mitochondrial pathway alignment.
Topics: Anticarcinogenic Agents; Apoptosis; Benzimidazoles; Carbocyanines; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Humans; Membrane Potentials; Mitochondria; Mitochondrial Membranes; Pancreatic Neoplasms; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
Effect of lime-induced leaf chlorosis on ochratoxin A, trans-resveratrol, and epsilon-viniferin production in grapevine (Vitis vinifera L.) berries infected by Aspergillus carbonarius.
Topics: Aspergillus; Benzofurans; Calcium Compounds; Fruit; Iron; Ochratoxins; Oxides; Plant Diseases; Plant Leaves; Resveratrol; Soil; Stilbenes; Vitis | 2008 |
Anti-inflammatory effect of resveratrol on TNF-alpha-induced MCP-1 expression in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Inflammatory Agents; Chemokine CCL2; Dose-Response Relationship, Drug; Inflammation; Mice; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2008 |
Resveratrol attenuates thromboxane A2 receptor agonist-induced platelet activation by reducing phospholipase C activity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Blood Platelets; Blotting, Western; Cardiotonic Agents; Enzyme Inhibitors; Estrenes; Flow Cytometry; Humans; In Vitro Techniques; Isoenzymes; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Pyrrolidinones; Receptors, Thromboxane A2, Prostaglandin H2; Resveratrol; Signal Transduction; Stilbenes; Type C Phospholipases | 2008 |
Effect of methyl jasmonate in combination with carbohydrates on gene expression of PR proteins, stilbene and anthocyanin accumulation in grapevine cell cultures.
Topics: Acetates; Acyltransferases; Anthocyanins; Carbohydrate Metabolism; Cyclopentanes; Fructose; Fruit; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucose; Oxylipins; Plant Growth Regulators; Resveratrol; Stilbenes; Sucrose; Sweetening Agents; Vitis; Wine | 2008 |
Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells.
Topics: Angiogenesis Inhibitors; Caveolin 1; Endothelium, Vascular; Estradiol; Estrogen Receptor alpha; Ethanol; Humans; Kinetics; Phosphorylation; Resveratrol; src-Family Kinases; Stilbenes; Umbilical Veins | 2008 |
A comparison of solid-phase microextraction and stir bar sorptive extraction coupled to liquid chromatography for the rapid analysis of resveratrol isomers in wines, musts and fruit juices.
Topics: Beverages; Chromatography, High Pressure Liquid; Fruit; Isomerism; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Wine | 2008 |
ORAC-fluorescein assay to determine the oxygen radical absorbance capacity of resveratrol complexed in cyclodextrins.
Topics: Antioxidants; Cyclodextrins; Fluorescein; Fluorescent Dyes; Reactive Oxygen Species; Resveratrol; Sensitivity and Specificity; Stilbenes | 2008 |
Dietary intake of flavonoids and hyperoxia-induced oxidative stress related cough in guinea pigs.
Topics: Animals; Antioxidants; Citric Acid; Cough; Flavonoids; Guinea Pigs; Hyperoxia; Male; Oxidative Stress; Resveratrol; Stilbenes | 2007 |
Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts.
Topics: Animals; Cardiovascular Agents; Cell Culture Techniques; Cells, Cultured; Collagen; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Glucose; Hyperglycemia; Interleukin-17; Male; Mice; Mice, Inbred C57BL; Myocardium; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, Interleukin; Receptors, Interleukin-17; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Time Factors; Up-Regulation | 2008 |
Stacking interaction study of trans-resveratrol (trans-3,5,4'-trihydroxystilbene) in solution by Nuclear Magnetic Resonance and Fourier Transform Infrared Spectroscopy.
Topics: Chemical Phenomena; Chemistry, Physical; Magnetic Resonance Spectroscopy; Molecular Structure; Resveratrol; Solutions; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2008 |
Resveratrol induces the suppression of tumor-derived CD4+CD25+ regulatory T cells.
Topics: Animals; Cells, Cultured; Female; Forkhead Transcription Factors; Immunosuppressive Agents; Interferon-gamma; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Resveratrol; Stilbenes; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2008 |
Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons.
Topics: Antioxidants; Apoptosis; Benzimidazoles; Catechin; Cells, Cultured; Central Nervous System Depressants; Curcumin; Ethanol; Fluorescent Dyes; Melatonin; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Resveratrol; Rhombencephalon; Signal Transduction; Stilbenes; Thioctic Acid | 2008 |
[Inhibit affection of resveratrol on the growth of Hep-2 cell line].
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2007 |
Resveratrol protects against arsenic trioxide-induced cardiotoxicity in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Calcium; Caspase 3; Cell Survival; Cytoplasm; Electrocardiography; Female; Heart Diseases; In Situ Nick-End Labeling; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Myocytes, Cardiac; Oxidative Stress; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
Resveratrol blocks high glucose-induced mitochondrial reactive oxygen species production in bovine aortic endothelial cells: role of phase 2 enzyme induction?
Topics: Animals; Antioxidants; Cattle; Cells, Cultured; Endothelial Cells; Glutathione; Glutathione Transferase; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
[Effects of resveratrol on matrix metalloproteinase-9 expression in hepatoma cells].
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Humans; Liver Neoplasms; Matrix Metalloproteinase 9; Resveratrol; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2008 |
HPLC-F analysis of melatonin and resveratrol isomers in wine using an SPE procedure.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Flavonoids; Isomerism; Melatonin; Molecular Structure; Phenols; Polyphenols; Resveratrol; Solid Phase Extraction; Stilbenes; Wine | 2008 |
Inhibition of cholinesterase and amyloid-beta aggregation by resveratrol oligomers from Vitis amurensis.
Topics: Amyloid beta-Peptides; Benzofurans; Cholinesterase Inhibitors; Cholinesterases; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Phenols; Plant Extracts; Polymers; Resveratrol; Stilbenes; Vitis | 2008 |
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Boronic Acids; Bortezomib; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dexamethasone; Drug Evaluation, Preclinical; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Oligonucleotide Array Sequence Analysis; Pyrazines; Resveratrol; Signal Transduction; Stilbenes; TCF Transcription Factors; Vidarabine; Waldenstrom Macroglobulinemia | 2008 |
Female rats fed a high-fat diet were associated with vascular dysfunction and cardiac fibrosis in the absence of overt obesity and hyperlipidemia: therapeutic potential of resveratrol.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Pressure; Dietary Fats; Female; Fibrosis; Hyperlipidemias; Myocardium; Nitroprusside; Obesity; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents; Ventricular Dysfunction, Left | 2008 |
Enhanced anti-proliferative effects of combinatorial treatment of delta-tocopherol and resveratrol in human HMC-1 cells.
Topics: alpha-Tocopherol; beta-Tocopherol; Cell Division; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; gamma-Tocopherol; Humans; Mast Cells; Mastocytoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Tocopherols | 2007 |
Differential effect of proIGF-II and IGF-II on resveratrol induced cell death by regulating survivin cellular localization and mitochondrial depolarization in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 7; Cell Line, Tumor; Cell Survival; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Insulin-Like Growth Factor II; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Mitochondria; Neoplasm Proteins; Protein Precursors; Protein Processing, Post-Translational; Resveratrol; Signal Transduction; Stilbenes; Survivin | 2007 |
Resveratrol counteracts gallic acid-induced down-regulation of gap-junction intercellular communication.
Topics: Animals; Antioxidants; Cell Communication; Connexin 43; Down-Regulation; Epithelial Cells; Gallic Acid; Gap Junctions; Hydrogen Peroxide; Liver; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2009 |
Resveratrol directly targets COX-2 to inhibit carcinogenesis.
Topics: Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatography, Affinity; Cyclooxygenase 2; Humans; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2008 |
Postischemic treatment by trans-resveratrol in rat liver ischemia-reperfusion: a possible strategy in liver surgery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Catalase; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hepatic Artery; Liver; Liver Circulation; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Vasodilator Agents | 2008 |
Inhibitory effects of trans-resveratrol analogs molecules on the proliferation and the cell cycle progression of human colon tumoral cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Membrane Permeability; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Flow Cytometry; Humans; Resveratrol; Stilbenes; Structure-Activity Relationship; Xenobiotics | 2008 |
Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Biological Availability; Blotting, Western; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Cytochromes c; Disease Models, Animal; Dose-Response Relationship, Drug; Intracellular Signaling Peptides and Proteins; Melanoma; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Mitochondrial Proteins; Resveratrol; Stilbenes; Transplantation, Heterologous; Uveal Neoplasms | 2008 |
Resveratrol inhibits cell growth in a human cholangiocarcinoma cell line.
Topics: Alkaline Phosphatase; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Karyotyping; L-Lactate Dehydrogenase; Microscopy, Electron, Scanning; Resveratrol; Stilbenes; Transglutaminases | 2008 |
Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1.
Topics: Acetylation; AMP-Activated Protein Kinases; Animals; Animals, Genetically Modified; Benzamides; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Survival; Chlorocebus aethiops; COS Cells; Forkhead Transcription Factors; Gene Expression Regulation; Genes, Reporter; Histones; Humans; Multienzyme Complexes; Muscles; Muscular Dystrophy, Oculopharyngeal; Naphthols; Peptide Initiation Factors; Peptides; Protein Serine-Threonine Kinases; Resveratrol; RNA-Binding Proteins; Sirtuins; Stilbenes; Transcription Factors | 2008 |
Resveratrol inhibits migration and invasion of human breast-cancer cells.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Enzyme Activation; Gene Expression; Humans; Insulin-Like Growth Factor I; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2008 |
Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens.
Topics: Benzhydryl Compounds; Blotting, Western; Cell Line, Tumor; Chlordecone; Diethylstilbestrol; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Fluorescence Resonance Energy Transfer; Humans; Phenols; Phytoestrogens; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sp1 Transcription Factor; Sp3 Transcription Factor; Sp4 Transcription Factor; Stilbenes; Transfection | 2008 |
Change in histone H3 phosphorylation, MAP kinase p38, SIR 2 and p53 expression by resveratrol in preventing streptozotocin induced type I diabetic nephropathy.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Histones; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Streptozocin; Tumor Suppressor Protein p53 | 2008 |
Inhibition of peroxide-induced radical generation by plant polyphenols in C6 astroglioma cells.
Topics: Astrocytoma; Benzene Derivatives; Brain Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Free Radical Scavengers; Free Radicals; Genistein; Luteolin; Oxidants; Oxidative Stress; Phenols; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2008 |
Porcine adipose triglyceride lipase complementary deoxyribonucleic acid clone, expression pattern, and regulation by resveratrol.
Topics: Adipose Tissue; Amino Acid Sequence; Animals; Base Sequence; DNA; Enzyme Inhibitors; Female; Gene Expression Regulation; Lipase; Molecular Biology; Molecular Sequence Data; Resveratrol; Stilbenes; Swine | 2008 |
EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol.
Topics: Dietary Supplements; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Oxygen Consumption; Pyrroles; Resveratrol; Spin Labels; Stilbenes; Superoxides; Uric Acid; Xanthine; Xanthine Oxidase | 2008 |
Phenolic composition in grape (Vitis vinifera L. cv. Malbec) ripened with different solar UV-B radiation levels by capillary zone electrophoresis.
Topics: Anthocyanins; Electrophoresis, Capillary; Flavonoids; Fruit; Phenols; Polyphenols; Resveratrol; Stilbenes; Sunlight; Ultraviolet Rays; Vitis | 2008 |
Antioxidant properties of resveratrol and piceid on lipid peroxidation in micelles and monolamellar liposomes.
Topics: Antioxidants; Butylated Hydroxytoluene; Glucosides; Lipid Peroxidation; Micelles; Models, Biological; Molecular Structure; Resveratrol; Stilbenes; Unilamellar Liposomes; Vitamin E | 2008 |
SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hypertension; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Niacinamide; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Resveratrol; RNA, Messenger; Sirtuin 1; Sirtuins; Sp1 Transcription Factor; Stilbenes; Time Factors; Transcription, Genetic; Transfection | 2008 |
Role of non-canonical Beclin 1-independent autophagy in cell death induced by resveratrol in human breast cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 7; Beclin-1; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Humans; Membrane Proteins; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Ubiquitin-Activating Enzymes; Vesicular Transport Proteins | 2008 |
Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities.
Topics: Antineoplastic Agents; Cell Survival; Enzyme Inhibitors; Humans; KB Cells; Phenols; Resveratrol; Stilbenes; Xanthine Oxidase | 2008 |
Prevention of estrogen-DNA adduct formation in MCF-10F cells by resveratrol.
Topics: Antioxidants; Breast Neoplasms; Cell Line, Tumor; Chromatography, Liquid; DNA Adducts; Estrogens; Female; Humans; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2008 |
Tissue distribution and excretion of resveratrol in rat after oral administration of Polygonum cuspidatum extract (PCE).
Topics: Administration, Oral; Animals; Bile; Chromatography, High Pressure Liquid; Fallopia japonica; Plant Extracts; Rats; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Tandem Mass Spectrometry; Tissue Distribution | 2008 |
Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Arteries; Carotid Arteries; Cells, Cultured; Coronary Vessels; Cytoprotection; DNA Damage; Endothelial Cells; Inflammation; Inflammation Mediators; Male; Mitochondria; Models, Animal; NF-kappa B; Oxidative Stress; Phenotype; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Sirtuins; Smoke; Smoking; Stilbenes; Vasodilation; Vasodilator Agents | 2008 |
Resveratrol inhibits electrical activity of paraventricular nucleus neurons in rat hypothalamic slices.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Glutamic Acid; In Vitro Techniques; Microelectrodes; Neurons; NG-Nitroarginine Methyl Ester; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways.
Topics: Animals; Antioxidants; Cholesterol, Dietary; Deoxyglucose; Dietary Carbohydrates; Fructose; Glucose; Glucose Clamp Technique; Insulin; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Resveratrol; Stilbenes | 2008 |
Precursor IGF-II (proIGF-II) and mature IGF-II (mIGF-II) induce Bcl-2 And Bcl-X L expression through different signaling pathways in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; bcl-X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cytochromes c; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Insulin-Like Growth Factor II; Intracellular Signaling Peptides and Proteins; Mitochondrial Membranes; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stilbenes | 2008 |
Resveratrol induces apoptosis in K562 (chronic myelogenous leukemia) cells by targeting a key survival protein, heat shock protein 70.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzoquinones; Blotting, Western; Caspase 3; Cell Nucleus; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Flow Cytometry; G1 Phase; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Lactams, Macrocyclic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Promoter Regions, Genetic; Resting Phase, Cell Cycle; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotide Reductases; RNA, Messenger; Stilbenes; Transcription Factors | 2008 |
Plant phenolic compounds as ethidium bromide efflux inhibitors in Mycobacterium smegmatis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Enzyme Inhibitors; Ethidium; Genistein; Luteolin; Membrane Transport Proteins; Microbial Sensitivity Tests; Mycobacterium smegmatis; Phenols; Resveratrol; Stilbenes; Verapamil | 2008 |
Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Antioxidants; Apoptosis; Blotting, Western; CCAAT-Enhancer-Binding Protein-alpha; Cell Survival; Cytochromes c; Cytosol; Drug Synergism; Mice; Microscopy, Fluorescence; PPAR gamma; Quercetin; Resveratrol; Stilbenes | 2008 |
Thiomethylstilbenes as inhibitors of CYP1A1, CYP1A2 and CYP1B1 activities.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Enzyme Inhibitors; Insecta; Kinetics; Microsomes; Resveratrol; Stilbenes; Sulfides | 2008 |
Quantification of free and protein-bound trans-resveratrol metabolites and identification of trans-resveratrol-C/O-conjugated diglucuronides - two novel resveratrol metabolites in human plasma.
Topics: Adult; Antineoplastic Agents, Phytogenic; Blood Proteins; Blotting, Western; Chromatography, High Pressure Liquid; Glucuronides; Humans; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Conformation; Protein Binding; Reference Values; Resveratrol; Stilbenes | 2008 |
Resveratrol protects rat striatal slices against anoxia-induced dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Animals; Antioxidants; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Female; Hypoxia; Male; Nomifensine; Ouabain; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2008 |
Vitamin E analog alpha-TEA, methylseleninic acid, and trans-resveratrol in combination synergistically inhibit human breast cancer cell growth.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Male; Organoselenium Compounds; Prostatic Neoplasms; Resveratrol; Stilbenes; Tocopherols; Vitamin E | 2008 |
Resveratrol from red grapes - pedestrian polyphenol or useful anticancer agent?
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Molecular Structure; Resveratrol; Stilbenes; Vitis | 2008 |
Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Drug Screening Assays, Antitumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Head and Neck Neoplasms; Humans; MAP Kinase Signaling System; Models, Biological; Neoplasms, Squamous Cell; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Phosphoserine; Promoter Regions, Genetic; Protein Binding; Protein Kinase Inhibitors; Resveratrol; Stilbenes; Subcellular Fractions; Sulfonamides; Tumor Suppressor Protein p53 | 2008 |
The effects of chronic resveratrol treatment on vascular responsiveness of streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Glucose; Blood Vessels; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thoracic Arteries; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin.
Topics: Adhesives; Administration, Topical; Animals; Antioxidants; Chromatography, High Pressure Liquid; Female; Flavonoids; Hydrogels; Mice; Mice, Nude; Pharmaceutical Solutions; Pharmaceutical Vehicles; Phenols; Polyphenols; Resveratrol; Skin Absorption; Solutions; Stilbenes; Viscosity; Water Loss, Insensible; Wine | 2008 |
Synthesis of new antioxidant conjugates and their in vitro hydrolysis with Stratum corneum enzymes.
Topics: alpha-Tocopherol; Antioxidants; Drug Stability; Esterases; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Resveratrol; Skin; Spectroscopy, Fourier Transform Infrared; Sterol Esterase; Stilbenes; Thioctic Acid | 2008 |
Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Chromones; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Gamma Rays; Humans; MAP Kinase Signaling System; Melanoma; Mice; Morpholines; Nitrobenzenes; Phosphoinositide-3 Kinase Inhibitors; Radiation-Sensitizing Agents; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Resveratrol inhibits cell growth by inducing cell cycle arrest in activated hepatic stellate cells.
Topics: Animals; Apoptosis; Cell Cycle; Cell Line; Cell Nucleus; Cell Proliferation; Cell Survival; Hepatocytes; Mice; Resveratrol; S Phase; Stilbenes | 2008 |
Correlative analyses of notch signaling with resveratrol-induced differentiation and apoptosis of human medulloblastoma cells.
Topics: Active Transport, Cell Nucleus; Amyloid Precursor Protein Secretases; Antineoplastic Agents; Antioxidants; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Enzyme Inhibitors; Homeodomain Proteins; Humans; Medulloblastoma; Receptor, Notch1; Receptor, Notch2; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor HES-1; Up-Regulation | 2008 |
Influence of pressing method on juice stilbene content in muscadine and bunch grapes.
Topics: Beverages; Cold Temperature; Food Handling; Freezing; Fruit; Glucosides; Hot Temperature; Polygalacturonase; Resveratrol; Stilbenes; Vitis | 2008 |
A positive feedback pathway of estrogen biosynthesis in breast cancer cells is contained by resveratrol.
Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Estrogens; Feedback, Physiological; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; RNA, Messenger; Stilbenes | 2008 |
Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Animals, Newborn; Cell Count; Disease Models, Animal; Docosahexaenoic Acids; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neurons; Resveratrol; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase | 2008 |
Benzanilides with spasmolytic activity: chemistry, pharmacology, and SAR.
Topics: Anilides; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Ileum; Inhibitory Concentration 50; Male; Muscle Contraction; Papillary Muscles; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Dietary resveratrol administration increases MnSOD expression and activity in mouse brain.
Topics: Animals; Antioxidants; Brain; Catalase; Citrate (si)-Synthase; Diet; Dietary Fats; Enzyme Activation; Glutathione Peroxidase; Liver; Mice; Mice, Inbred C57BL; Mitochondria; Myocardium; Resveratrol; Stilbenes; Superoxide Dismutase | 2008 |
Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.
Topics: Antioxidants; Cell Line; Combinatorial Chemistry Techniques; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inhibitory Concentration 50; NF-kappa B; Resveratrol; Small Molecule Libraries; Stilbenes; Structure-Activity Relationship | 2009 |
Antioxidant protection of resveratrol and catechin in Saccharomyces cerevisiae.
Topics: Antioxidants; Catalase; Catechin; Hydrogen Peroxide; Lipid Peroxidation; Oxidative Stress; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2008 |
Resveratrol reduces radiation-induced chromosome aberration frequencies in mouse bone marrow cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Gamma Rays; Male; Mice; Mice, Inbred CBA; Models, Statistical; Radiation-Protective Agents; Resveratrol; Stilbenes; Whole-Body Irradiation | 2008 |
Resveratrol attenuates early pyramidal neuron excitability impairment and death in acute rat hippocampal slices caused by oxygen-glucose deprivation.
Topics: Action Potentials; Animals; Antioxidants; Carbocyanines; Cell Death; Hippocampus; Hypoxia-Ischemia, Brain; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Nerve Degeneration; Organ Culture Techniques; Potassium Channel Blockers; Pyramidal Cells; Rats; Resveratrol; Stilbenes; Time Factors | 2008 |
Resveratrol displays converse dose-related effects on 5-fluorouracil-evoked colon cancer cell apoptosis: the roles of caspase-6 and p53.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 6; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Activation; Fluorouracil; HCT116 Cells; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2008 |
Novel resveratrol analogs induce apoptosis and cause cell cycle arrest in HT29 human colon cancer cells: inhibition of ribonucleotide reductase activity.
Topics: Anisoles; Antineoplastic Agents; Apoptosis; Cell Cycle; Chromatography, High Pressure Liquid; Deoxyribonucleotides; HT29 Cells; Humans; Molecular Structure; Pyrogallol; Resveratrol; Ribonucleotide Reductases; Stilbenes; Tumor Stem Cell Assay | 2008 |
Design, synthesis and spectroscopic studies of resveratrol aliphatic acid ligands of human serum albumin.
Topics: Acetates; Biological Availability; Caproates; Drug Design; Fatty Acids; Humans; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Phenols; Phenoxyacetates; Protein Conformation; Proton-Translocating ATPases; Resveratrol; Serum Albumin; Software; Solubility; Stilbenes | 2008 |
Resveratrol improves non-alcoholic fatty liver disease by activating AMP-activated protein kinase.
Topics: Animals; Antioxidants; Cyclic AMP-Dependent Protein Kinases; Diet; Enzyme Activation; Fatty Liver; Glucose Clamp Technique; Humans; Hyperinsulinism; Liver; Male; Rats; Resveratrol; Stilbenes; Triglycerides | 2008 |
Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention.
Topics: Anticarcinogenic Agents; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Cell Size; Colon; Colonic Neoplasms; Humans; Intestinal Mucosa; Resveratrol; Stilbenes; Wnt Proteins | 2008 |
[Effect of resveratrol on chronic obstructive pulmonary disease in rats and its mechanism].
Topics: Animals; Bleomycin; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Female; Forced Expiratory Volume; Intercellular Adhesion Molecule-1; Lung; Lung Compliance; Male; Maximal Midexpiratory Flow Rate; Pulmonary Disease, Chronic Obstructive; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Smoking; Stilbenes | 2008 |
Induction of apoptosis in Jeko-1 mantle cell lymphoma cell line by resveratrol: a proteomic analysis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Electrophoresis, Gel, Two-Dimensional; Humans; Lymphoma, Mantle-Cell; Proteome; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2008 |
[Effects of garlic oil combined with resveratrol on inducting of apoptosis and expression of Fas, bcl-2 and bax in human gastric cancer cell line].
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; fas Receptor; Garlic; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Messenger; Stilbenes; Stomach Neoplasms | 2008 |
Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships.
Topics: Animals; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; I-kappa B Proteins; Lipopolysaccharides; Microglia; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Solutions; Stilbenes; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2008 |
In vitro evaluation of the cytotoxic and anti-proliferative properties of resveratrol and several of its analogs.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Proliferation; Cell Survival; Humans; Macrophages; Mice; Molecular Structure; Resveratrol; Stilbenes | 2008 |
Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Colorectal Neoplasms; DNA Fragmentation; HT29 Cells; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.
Topics: Aging; Animals; Caloric Restriction; Endocrine Glands; Gene Expression Profiling; Glucose; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Oxidative Stress; Resveratrol; Stilbenes | 2008 |
Study of vacuum microwave-assisted extraction of polyphenolic compounds and pigment from Chinese herbs.
Topics: Chemical Fractionation; Coloring Agents; Coumaric Acids; Drugs, Chinese Herbal; Emodin; Flavonoids; Glucosides; Microwaves; Myrica; Phenols; Plant Leaves; Polyphenols; Quercetin; Reproducibility of Results; Resveratrol; Stilbenes; Vacuum | 2008 |
[Studies on chemical constituents from roots of Caragana sinica].
Topics: Caragana; Chromatography, Gel; Drugs, Chinese Herbal; Molecular Structure; Parabens; Plant Roots; Resveratrol; Stilbenes | 2008 |
Comparison of the phytohormones genistein, resveratrol and 8-prenylnaringenin as agents for preventing osteoporosis.
Topics: Animals; Biomechanical Phenomena; Bone Density; Flavanones; Genistein; Osteoporosis; Plant Growth Regulators; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tibia | 2008 |
Resveratrol attenuates adenosine diphosphate-induced platelet activation by reducing protein kinase C activity.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Membrane; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fallopia japonica; Humans; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Protein Kinase C; Resveratrol; Stilbenes | 2008 |
[Inhibitory effect of resveratrol on cardiac fibroblast proliferation induced by angiotensin II].
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Cyclic GMP; Fibroblasts; Gene Expression; Heart; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
RV09, a novel resveratrol analogue, inhibits NO and TNF-alpha production by LPS-activated microglia.
Topics: Animals; Antioxidants; Cell Line; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2008 |
Pterostilbene is equally potent as resveratrol in inhibiting 12-O-tetradecanoylphorbol-13-acetate activated NFkappaB, AP-1, COX-2, and iNOS in mouse epidermis.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epidermis; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide Synthase Type II; Proteasome Endopeptidase Complex; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Gene Expression; Glucose; Insulin; Mice; PPAR gamma; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Resveratrol; Stilbenes; Transcription, Genetic | 2008 |
Low Sirt1 expression, which is upregulated by fasting, in human adipose tissue from obese women.
Topics: Adipocytes; Adult; Cell Differentiation; Cells, Cultured; Enzyme Activation; Fasting; Female; Humans; Lipolysis; Middle Aged; Obesity; Resveratrol; RNA, Messenger; Sirtuin 1; Sirtuins; Stilbenes; Subcutaneous Fat; Thinness; Up-Regulation | 2008 |
Resveratrol inhibits cardiac hypertrophy via AMP-activated protein kinase and Akt.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Mice; Multienzyme Complexes; Myocytes, Cardiac; Peptide Elongation Factor 2; Phenylephrine; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Stilbenes; Transcription, Genetic | 2008 |
SIRT1 promotes differentiation of normal human keratinocytes.
Topics: Calcium; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Keratinocytes; Models, Biological; Models, Genetic; Niacinamide; Oligonucleotide Array Sequence Analysis; Plasmids; Resveratrol; RNA Interference; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic | 2009 |
Trans-resveratrol inhibits early blood vessel formation (vasculogenesis) without impairment of embryonic growth.
Topics: Angiogenesis Inhibitors; Animals; Chick Embryo; Embryonic Development; Fibroblast Growth Factor 2; Neovascularization, Physiologic; Phorbol 12,13-Dibutyrate; Protein Kinase C; Resveratrol; Stilbenes | 2008 |
Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; CSK Tyrosine-Protein Kinase; Cyclin D1; Cyclin-Dependent Kinase 2; DNA Replication; Humans; Inhibitory Concentration 50; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Rats; Receptors, Platelet-Derived Growth Factor; Resveratrol; Retinoblastoma Protein; Signal Transduction; Sirtuin 1; Sirtuins; src-Family Kinases; Stilbenes | 2008 |
Antiteratogenic effect of resveratrol in mice exposed in utero to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Cleft Palate; Dilatation, Pathologic; Female; Hydronephrosis; Male; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Receptors, Aryl Hydrocarbon; Resveratrol; Severity of Illness Index; Stilbenes; Teratogens | 2008 |
Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors.
Topics: Angiogenic Proteins; Animals; Blotting, Western; Brain; Coloring Agents; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred BALB C; Microcirculation; Motor Activity; Neovascularization, Physiologic; Neuroprotective Agents; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Stroke; Tetrazolium Salts; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
ERK1/2 activation is required for resveratrol-induced apoptosis in MDA-MB-231 cells.
Topics: Anticarcinogenic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Small Interfering; Stilbenes | 2008 |
Antimalarial activity in mice of resveratrol derivative from Pleuropterus ciliinervis.
Topics: Animals; Antimalarials; Drug Resistance; Malaria; Male; Mice; Mice, Inbred ICR; Plant Roots; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Polygonaceae; Resveratrol; Stilbenes | 2008 |
Spinal nerve ligation reduces nitric oxide synthase activity and expression: effect of resveratrol.
Topics: Actins; Animals; Antioxidants; Female; Injections, Spinal; Ligation; Nitric Oxide; Nitric Oxide Synthase Type I; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Resveratrol; Spinal Cord; Spinal Nerves; Stilbenes | 2008 |
Resveratrol disrupts peroxynitrite-triggered mitochondrial apoptotic pathway: a role for Bcl-2.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cardiovascular Diseases; Caspases; Cattle; Cells, Cultured; Cytoprotection; Endothelial Cells; Mitochondria; Oxidative Stress; Peroxynitrous Acid; Proto-Oncogene Proteins c-bcl-2; Receptors, Death Domain; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Synthesis and biological evaluation of cytotoxic properties of stilbene-based resveratrol analogs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Embryonic Development; Erythrocytes; Hemolysis; Humans; Inhibitory Concentration 50; Mice; Ovum; Resveratrol; Sea Urchins; Stilbenes | 2009 |
Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo.
Topics: Androgens; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Estradiol; Gene Expression Profiling; Humans; Male; Metribolone; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; Receptor, IGF Type 1; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Transplantation, Heterologous | 2008 |
Resveratrol reduces endothelial progenitor cells senescence through augmentation of telomerase activity by Akt-dependent mechanisms.
Topics: Adult; Blotting, Western; Cardiotonic Agents; Cell Movement; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dose-Response Relationship, Drug; Endothelial Cells; Female; Humans; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stem Cells; Stilbenes; Telomerase | 2008 |
Chain-breaking activity of resveratrol and piceatannol in a linoleate micellar model.
Topics: Chemistry, Physical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Linoleic Acid; Lipid Peroxidation; Micelles; Models, Chemical; Oxidation-Reduction; Oxygen; Resveratrol; Stilbenes | 2008 |
Insights into the pharmacological potential of estrogens and phytoestrogens on catecholamine signaling.
Topics: Animals; Cardiovascular System; Catecholamines; Cattle; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Intracellular Space; Isoflavones; Models, Biological; Phytoestrogens; Protective Agents; Receptors, Estrogen; Resveratrol; Signal Transduction; Stilbenes | 2008 |
Inhibition of STAT3 expression and signaling in resveratrol-differentiated medulloblastoma cells.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Survival; Cerebellar Neoplasms; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Leukemia Inhibitory Factor; Medulloblastoma; Neurons; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tumor Cells, Cultured; Tyrphostins | 2008 |
A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells.
Topics: Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Fluorescent Dyes; Humans; Isoenzymes; Molecular Structure; Polychlorinated Dibenzodioxins; Prodrugs; Resveratrol; Rhodamines; Stilbenes; Structure-Activity Relationship | 2008 |
The effects of dietary phenolic compounds on cytokine and antioxidant production by A549 cells.
Topics: Antioxidants; Beverages; Cell Line; Cytokines; Diet; Fruit; Glutathione; Humans; Interleukin-1; Oxidation-Reduction; Phenols; Pulmonary Alveoli; Quercetin; Resveratrol; Rosaceae; Stilbenes | 2008 |
Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Topics: Age Factors; Aging; Animals; Antioxidants; Apoptosis; Caloric Restriction; Cardiovascular System; Energy Intake; Food Deprivation; Food, Formulated; Gene Expression Regulation; Inflammation; Longevity; Male; Mice; Mice, Inbred C57BL; Osteoporosis; Resveratrol; Stilbenes; Transcription, Genetic; Treatment Outcome | 2008 |
Stimulation of muscle cell glucose uptake by resveratrol through sirtuins and AMPK.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Biological Transport; Cell Line; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Indinavir; Muscle Fibers, Skeletal; Niacinamide; Phosphorylation; Protein Kinases; Rats; Resveratrol; Sirtuins; Stilbenes | 2008 |
Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis Regulatory Proteins; Cell Cycle; Drug Synergism; Female; Humans; Indoles; Nitric Oxide; Ovarian Neoplasms; Oxazines; Resveratrol; Staining and Labeling; Stilbenes; Xanthenes | 2008 |
Resveratrol suppresses interleukin-1beta-induced inflammatory signaling and apoptosis in human articular chondrocytes: potential for use as a novel nutraceutical for the treatment of osteoarthritis.
Topics: Apoptosis; Blotting, Western; Cartilage, Articular; Cell Nucleus; Cells, Cultured; Chondrocytes; Dietary Supplements; Dose-Response Relationship, Drug; Extracellular Matrix; Humans; Inflammation Mediators; Interleukin-1beta; Microscopy, Electron, Transmission; NF-kappa B; Osteoarthritis; Protein Transport; Resveratrol; Signal Transduction; Stilbenes | 2008 |
In vitro antiviral activity of resveratrol against respiratory viruses.
Topics: Adenoviridae; Antioxidants; Antiviral Agents; Cell Line; Humans; Influenza A virus; Respiratory Syncytial Viruses; Respiratory Tract Infections; Resveratrol; Stilbenes | 2008 |
The convenient synthesis and evaluation of the anticancer activities of new resveratrol derivatives.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes | 2009 |
Long-term effects of resveratrol supplementation on suppression of atherogenic lesion formation and cholesterol synthesis in apo E-deficient mice.
Topics: Acetyl-CoA C-Acetyltransferase; Animals; Antioxidants; Aorta; Apolipoproteins E; Aryldialkylphosphatase; Atherosclerosis; Cholesterol; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Lipid Peroxidation; Liver; Male; Mice; Mice, Mutant Strains; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2008 |
Localization of stilbene synthase in Vitis vinifera L. during berry development.
Topics: Acyltransferases; Antibodies; Chromatography, High Pressure Liquid; Fluorescent Antibody Technique; Fruit; Plant Epidermis; Protein Transport; Resveratrol; Stilbenes; Subcellular Fractions; Subcutaneous Tissue; Vitis | 2008 |
Neuroprotective effects of resveratrol on MPTP-induced neuron loss mediated by free radical scavenging.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Ataxia; Corpus Striatum; Free Radical Scavengers; Hand Strength; Male; Mice; Mice, Inbred BALB C; Motor Activity; Neurons; Neuroprotective Agents; Parkinson Disease, Secondary; Resveratrol; Stilbenes | 2008 |
Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes.
Topics: Animals; Antioxidants; Blotting, Western; Cells, Cultured; Enzymes; Gene Expression Regulation; Hepatocytes; Male; Necrosis; NF-E2-Related Factor 2; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2008 |
Kaempferol, but not resveratrol inhibits angiotensin converting enzyme.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Kaempferols; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Resveratrol; Stilbenes | 2008 |
Inhibition of acrylamide toxicity in mice by three dietary constituents.
Topics: Acrylamide; Allyl Compounds; Animals; Creatine Kinase; Diet; DNA Adducts; Enzyme Inhibitors; Flavonoids; Glutathione; Glutathione Transferase; Hemoglobins; Liver; Male; Mice; Mice, Inbred ICR; Phenols; Polyphenols; Protamines; Resveratrol; Stilbenes; Sulfides; Tea | 2008 |
The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Oral; Animals; beta-Cyclodextrins; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes | 2008 |
Study of resveratrol and antioxidant activity in Georgian brand red wines and a number of foreign red wines.
Topics: Antioxidants; Georgia (Republic); Humans; Hyperlipoproteinemias; Lipid Peroxidation; Phenols; Resveratrol; Stilbenes; Vitis; Wine | 2008 |
Optimization of solid-liquid extraction of resveratrol and other phenolic compounds from milled grape canes (Vitis vinifera).
Topics: Benzofurans; Coumaric Acids; Ethanol; Phenols; Plant Stems; Resveratrol; Solutions; Solvents; Stilbenes; Temperature; Vitis | 2008 |
Resveratrol reduces infarct size and improves ventricular function after myocardial ischemia in rats.
Topics: Animals; Antioxidants; Atrial Natriuretic Factor; Collagen Type I; Echocardiography; Hemodynamics; Male; Mice; Myocardial Ischemia; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Ventricular Remodeling | 2008 |
Resveratrol modulates innate and inflammatory responses in fish leucocytes.
Topics: Animals; Cell Movement; Cells, Cultured; Dinoprostone; Flatfishes; Gene Expression Regulation; Immunity, Innate; Inflammation; Kidney; Leukocytes; Peroxidase; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
Analysis of selected stilbenes in Polygonum cuspidatum by HPLC coupled with CoulArray detection.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Fallopia japonica; Glucosides; Hydrogen-Ion Concentration; Plant Roots; Resveratrol; Stilbenes | 2008 |
Resveratrol inhibits EMMPRIN expression via P38 and ERK1/2 pathways in PMA-induced THP-1 cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Basigin; Cell Line; Cell Survival; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
Resveratrol reverses ET-1-evoked mitogenic effects in human coronary arterial cells by activating the kinase-G to inhibit ERK-enzymes.
Topics: Antineoplastic Agents, Phytogenic; Carbazoles; Cell Division; Cells, Cultured; Coronary Vessels; Cyclic GMP-Dependent Protein Kinases; Drug Interactions; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; Humans; In Vitro Techniques; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogens; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Protein Kinase Inhibitors; Pyrroles; Resveratrol; Stilbenes | 2009 |
Selective growth inhibition of human leukemia and human lymphoblastoid cells by resveratrol via cell cycle arrest and apoptosis induction.
Topics: Anticarcinogenic Agents; Apoptosis; B-Lymphocytes; Cell Cycle; Cell Division; Cell Line; HL-60 Cells; Humans; Leukemia; Micronucleus Tests; Resveratrol; Stilbenes | 2008 |
Short-term consumption of a resveratrol-containing nutraceutical mixture mimics gene expression of long-term caloric restriction in mouse heart.
Topics: Aging; Animals; Blood Glucose; Body Weight; Caloric Restriction; Dietary Supplements; Drug Evaluation, Preclinical; Gene Expression Profiling; Gene Expression Regulation; Insulin; Male; Mice; Mice, Inbred Strains; Myocardium; Oligonucleotide Array Sequence Analysis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2008 |
Protection of human colon epithelial cells against deoxycholate by rottlerin.
Topics: Acetophenones; Apoptosis; Benzopyrans; Biphenyl Compounds; Caspase 3; Colon; Cytochromes c; Cytoprotection; Deoxycholic Acid; DNA Damage; DNA, Neoplasm; Epithelial Cells; HCT116 Cells; Humans; Hydrazines; Mitochondria; Phenols; Picrates; Quercetin; Resveratrol; Stilbenes; Superoxides | 2008 |
Grapes and human health: a perspective.
Topics: Alzheimer Disease; Animals; Anticarcinogenic Agents; Diet; Fruit; Health Promotion; Humans; Resveratrol; Stilbenes; Urinary Bladder Diseases; Vitis | 2008 |
[Suppressive effect in vitro of resveratrol on ADP induced human platelet aggregation and its active mechanism].
Topics: Adenosine Diphosphate; Blood Platelets; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Fibrinogen; Humans; Phospholipase C beta; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrrolidinones; Resveratrol; Stilbenes | 2008 |
Microinjection of resveratrol into rostral ventrolateral medulla decreases sympathetic vasomotor tone through nitric oxide and intracellular Ca2+ in anesthetized male rats.
Topics: Anesthesia; Animals; Blood Pressure; Calcium Signaling; Drug Interactions; Enzyme Inhibitors; Heart Rate; Male; Medulla Oblongata; Microinjections; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Renal Circulation; Resveratrol; Stilbenes; Sympathetic Nervous System | 2008 |
Negative regulation of quinone reductase 2 by resveratrol in cultured vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Quinone Reductases; Rabbits; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors | 2008 |
Resveratrol protects primary rat hepatocytes against necrosis induced by reactive oxygen species.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hepatocytes; Male; Necrosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
Resveratrol inhibits hypoxia-induced metastasis potential enhancement by restricting hypoxia-induced factor-1 alpha expression in colon carcinoma cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Survival; Colonic Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Metastasis; Resveratrol; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A | 2008 |
Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; Male; Niacinamide; Phytoalexins; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Streptozocin; Terpenes | 2008 |
Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity.
Topics: Adrenergic Agents; Antioxidants; Blotting, Western; Caspase 3; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Oxidative Stress; Oxidopamine; Plant Extracts; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
Growth inhibition of human colon cancer cells by plant compounds.
Topics: Acrolein; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Piperidines; Plant Extracts; Resveratrol; Stilbenes | 2008 |
Microwave-assisted aqueous two-phase extraction of piceid, resveratrol and emodin from Polygonum cuspidatum by ethanol/ammonium sulphate systems.
Topics: Acetonitriles; Ammonium Sulfate; Chromatography, High Pressure Liquid; Emodin; Ethanol; Fallopia japonica; Glucosides; Microwaves; Plant Extracts; Resveratrol; Stilbenes | 2008 |
Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Curcumin; Disease Models, Animal; Ferric Compounds; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Melatonin; Metals, Heavy; Nitrilotriacetic Acid; Organ Size; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2008 |
Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Apoptosis; Base Sequence; DNA Primers; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Lipid Metabolism; Mice; Resveratrol; Stilbenes | 2008 |
Analysis of trans-resveratrol in grapes by micro-high performance liquid chromatography.
Topics: Antioxidants; China; Chromatography, High Pressure Liquid; Geography; Humans; Isomerism; Resveratrol; Stilbenes; Vitis | 2008 |
Resveratrol exerts pharmacological preconditioning by activating PGC-1alpha.
Topics: Antioxidants; Humans; Ischemic Preconditioning; Models, Biological; Models, Theoretical; Neovascularization, Pathologic; Nitric Oxide Synthase; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Reperfusion Injury; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors; Transcriptional Activation | 2008 |
Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor.
Topics: Animals; Antioxidants; Blotting, Western; Caveolin 1; Coronary Circulation; Heart; Heme Oxygenase-1; Hypercholesterolemia; Immunohistochemistry; Male; Mice; Mice, Transgenic; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2008 |
Aggregation state and pKa values of (E)-resveratrol as determined by fluorescence spectroscopy and UV-visible absorption.
Topics: Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Resveratrol; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Stilbenes | 2008 |
Resveratrol reestablishes spermatogenesis after testicular injury in rats caused by 2, 5-hexanedione.
Topics: Animals; Body Weight; Hexanones; Immunohistochemistry; Male; Organ Size; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Seminiferous Tubules; Spermatogenesis; Stilbenes; Testis | 2008 |
[Regulatory effect of resveratrol on JAK1/STAT3 signal transduction pathway in leukemia].
Topics: Animals; Antineoplastic Agents, Phytogenic; Down-Regulation; Janus Kinase 1; Leukemia L1210; Mice; Mice, Inbred BALB C; Random Allocation; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2008 |
Effect of resveratrol incorporated in liposomes on proliferation and UV-B protection of cells.
Topics: Cell Line; Cell Proliferation; Cell Shape; Cell Survival; Dose-Response Relationship, Drug; Drug Compounding; Drug Stability; Epithelial Cells; Humans; Lipids; Liposomes; Microscopy, Fluorescence; Particle Size; Resveratrol; Stilbenes; Sunscreening Agents; Time Factors; Ultraviolet Rays | 2008 |
In vino, curationis?
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluorouracil; HCT116 Cells; Humans; Resveratrol; Sirtuins; Stilbenes; Wine | 2008 |
Zhangfei induces the expression of the nerve growth factor receptor, trkA, in medulloblastoma cells and causes their differentiation or apoptosis.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Basic-Leucine Zipper Transcription Factors; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Early Growth Response Protein 1; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; PC12 Cells; Rats; Receptor, Nerve Growth Factor; Receptor, trkA; Resveratrol; Stilbenes; Time Factors; Transfection | 2009 |
[Resveratrol improves high-fat induced nonalcoholic fatty liver in rats].
Topics: AMP-Activated Protein Kinases; Animals; Fatty Liver; Insulin Resistance; Male; Phytotherapy; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2008 |
Protective effect of resveratrol in endotoxemia-induced acute phase response in rats.
Topics: Acute-Phase Reaction; Animals; Antioxidants; Blood Platelets; Body Temperature; Catalase; Disease Models, Animal; Drug Antagonism; Endotoxemia; Erythrocytes; Fever; Injections, Intraperitoneal; Iron; Leukocytes; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
Resveratrol alleviates alcoholic fatty liver in mice.
Topics: Adenylate Kinase; Adiponectin; Animals; Ethanol; Fatty Liver, Alcoholic; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptors, Adiponectin; Resveratrol; Sirtuin 1; Sirtuins; Sterol Regulatory Element Binding Protein 1; Stilbenes; Trans-Activators; Transcription Factors; Up-Regulation | 2008 |
Inhibitory effects of genistein and resveratrol on guinea pig gallbladder contractility in vitro.
Topics: Acetylcholine; Animals; Calcium Chloride; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gallbladder; Genistein; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Organometallic Compounds; Phenanthrolines; Phytoestrogens; Potassium Chloride; Protein Tyrosine Phosphatases; Resveratrol; Stilbenes | 2008 |
The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production.
Topics: Adenosine Triphosphate; Analysis of Variance; Annexin A5; Antioxidants; Apoptosis; Blotting, Western; Cartilage; Chondrocytes; Cyclooxygenase 2; Cytochromes c; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-1beta; Leukotriene B4; Matrix Metalloproteinases; Membrane Potential, Mitochondrial; Mitochondria; Osteoarthritis; Proteoglycans; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2008 |
Survey of the trans-resveratrol and trans-piceid content of cocoa-containing and chocolate products.
Topics: Beverages; Cacao; Carbohydrates; Diet; Fruit; Glucosides; Powders; Resveratrol; Stilbenes; Vitis; Wine | 2008 |
Action of resveratrol alone or in combination with roscovitine, a CDK inhibitor, on cell cycle progression in human HL-60 leukemia cells.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinases; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Phosphorylation; Protein Kinase Inhibitors; Purines; Resveratrol; Roscovitine; Stilbenes | 2008 |
The resveratrol analogue 3,5,3',4',5'-pentahydroxy-trans-stilbene inhibits cell transformation via MEK.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Molecular; Molecular Structure; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Resveratrol; Ribosomal Protein S6 Kinases, 90-kDa; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2008 |
Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol.
Topics: Adipocytes; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Fatty Acids; Humans; Inflammation Mediators; Insulin Resistance; Linoleic Acids, Conjugated; Middle Aged; PPAR gamma; Resveratrol; Stilbenes; Transfection; Triglycerides | 2009 |
trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Degranulation; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophil Peroxidase; Eosinophils; Humans; Inhibitory Concentration 50; Leukotriene C4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Stilbenes; Time Factors; Wine | 2008 |
Resveratrol inhibits nonalcoholic fatty liver disease in rats.
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Fatty Liver; Glucose; Glutathione Peroxidase; Lipid Peroxidation; Male; Malondialdehyde; Nitric Oxide Synthase; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Resveratrol; Severity of Illness Index; Stilbenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2008 |
Resveratrol, a new biomarker of moderate wine intake?
Topics: Alcohol Drinking; Biomarkers; Humans; Resveratrol; Sensitivity and Specificity; Stilbenes; Wine | 2009 |
Resveratrol, a unique phytoalexin present in red wine, delivers either survival signal or death signal to the ischemic myocardium depending on dose.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Male; Myocardial Ischemia; NF-kappa B; Oxidation-Reduction; Phytoalexins; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Signal Transduction; Stilbenes; Terpenes; Wine | 2009 |
Resveratrol modulates pyrogallol-induced changes in hepatic toxicity markers, xenobiotic metabolizing enzymes and oxidative stress.
Topics: Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Bilirubin; Biomarkers; Catalysis; Chemical and Drug Induced Liver Injury; Dermatologic Agents; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Oxidative Stress; Pyrogallol; Resveratrol; Stilbenes; Transaminases; Xenobiotics | 2008 |
Chemopreventive potential of resveratrol in mouse skin tumors through regulation of mitochondrial and PI3K/AKT signaling pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinogens; Caspases; Cytochromes c; Cytosol; Down-Regulation; Enzyme Activation; Female; Inhibitor of Apoptosis Proteins; Mice; Microtubule-Associated Proteins; Mitochondria; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Repressor Proteins; Resveratrol; Signal Transduction; Skin Neoplasms; Stilbenes; Survivin; Tumor Suppressor Protein p53 | 2009 |
Sirt1 is involved in energy metabolism: the role of chronic ethanol feeding and resveratrol.
Topics: Animals; Energy Metabolism; Ethanol; Feeding Behavior; Flavanones; Liver; Male; PPAR gamma; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Up-Regulation | 2008 |
Selective on-line extraction of trans-resveratrol and emodin from Polygonum cuspidatum using molecularly imprinted polymer.
Topics: Chromatography, High Pressure Liquid; Emodin; Fallopia japonica; Polymers; Resveratrol; Stilbenes | 2008 |
A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine.
Topics: DNA, Complementary; Methyltransferases; Molecular Sequence Data; Resveratrol; Stilbenes; Stress, Physiological; Vitis | 2008 |
Reversal effect of resveratrol on multidrug resistance in KBv200 cell line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Vincristine | 2008 |
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds.
Topics: Aging; Ascorbic Acid; Cell Line; Citric Acid; Collagen Type I; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Fibrosis; Glycolates; Humans; Lactic Acid; Linoleic Acids, Conjugated; Resveratrol; Stilbenes; Undecylenic Acids; Vitamin A | 2008 |
Effects of resveratrol pretreatment on tert-butylhydroperoxide induced hepatocyte toxicity in immobilized perifused hepatocytes: involvement of inducible nitric oxide synthase and hemoxygenase-1.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Apoptosis; Biomarkers, Tumor; Cells, Cultured; Cells, Immobilized; Cytoprotection; Heme Oxygenase-1; Hepatocytes; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Silymarin; Stilbenes; tert-Butylhydroperoxide | 2009 |
Suppression of cell proliferation and gene expression by combinatorial synergy of EGCG, resveratrol and gamma-tocotrienol in estrogen receptor-positive MCF-7 breast cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Catechin; Cell Line, Tumor; Cell Proliferation; Chromans; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Biological; Resveratrol; Stilbenes; Superoxide Dismutase; Vitamin E | 2008 |
Antinociceptive effect of resveratrol in carrageenan-evoked hyperalgesia in rats: prolonged effect related to COX-2 expression impairment.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Dose-Response Relationship, Drug; Down-Regulation; Hyperalgesia; Male; Pain Threshold; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Touch | 2008 |
A role of ion channels in the endothelium-independent relaxation of rat mesenteric artery induced by resveratrol.
Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Ion Channels; Male; Mesenteric Arteries; Muscle Relaxation; Nifedipine; Potassium; Potassium Channel Blockers; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents | 2008 |
Inhibitory effect of a novel resveratrol derivative on nitric oxide production in lipopolysaccharide-activated microglia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cell Survival; Free Radical Scavengers; Humans; Indicators and Reagents; Lipopolysaccharides; Microglia; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitrites; Nitroprusside; Reactive Nitrogen Species; Resveratrol; Stilbenes | 2008 |
[Protective effect of resveratrol on the intestinal mucosal cells in rats with severe acute pancreatitis and the mechanism].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; In Situ Nick-End Labeling; Intestinal Mucosa; Male; Membrane Potential, Mitochondrial; Microscopy, Confocal; Pancreatitis, Acute Necrotizing; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride; Stilbenes | 2008 |
Does white wine qualify for French paradox? Comparison of the cardioprotective effects of red and white wines and their constituents: resveratrol, tyrosol, and hydroxytyrosol.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotonic Agents; Heart; Humans; In Vitro Techniques; Male; Mitochondrial Swelling; Myocardial Ischemia; Myocardium; Peroxides; Phenylethyl Alcohol; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wine | 2008 |
Dietary trans-resveratrol bioavailability and effect on CCl4-induced liver lipid peroxidation.
Topics: Animals; Antioxidants; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Diet; Disease Models, Animal; Intubation, Gastrointestinal; Lipid Peroxidation; Liver; Liver Diseases; Male; Malondialdehyde; Plant Stems; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitis | 2009 |
Development of mitochondria-targeted derivatives of resveratrol.
Topics: Animals; Antioxidants; Cations; Chemistry, Pharmaceutical; Drug Design; Flavonoids; Mitochondria; Mitochondria, Liver; Oxidants; Oxidation-Reduction; Phenols; Polyphenols; Rats; Reactive Oxygen Species; Resveratrol; Solubility; Stilbenes; Water | 2008 |
Inhibition of transcriptional activity of c-JUN by SIRT1.
Topics: Animals; Antioxidants; Cell Line; Female; Gene Expression Regulation; Humans; Immunoprecipitation; Male; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Proto-Oncogene Proteins c-jun; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Transcription, Genetic; Two-Hybrid System Techniques | 2008 |
[The mechanism of resveratrol on anti-hepatoma Bel-7402 and modulating IL-8 in tumor model mice].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flow Cytometry; Interleukin-8; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2008 |
Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated mice.
Topics: Age Factors; Aging; Animals; Biomarkers; Energy Metabolism; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Male; Mice; Mice, Mutant Strains; Mitochondria, Muscle; Mitochondrial Proteins; Muscle Strength; Muscle, Skeletal; Oxygen Consumption; Physical Endurance; Physical Exertion; Resveratrol; RNA, Messenger; Running; Stilbenes; Time Factors | 2009 |
Resveratrol protects auditory hair cells from gentamicin toxicity.
Topics: Animals; Antioxidants; Enzyme Inhibitors; Gentamicins; Hair Cells, Auditory; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice.
Topics: Animals; Anticarcinogenic Agents; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Chromosomal Instability; DNA Damage; DNA Repair; Down-Regulation; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Genomic Instability; Gestational Age; Heterochromatin; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitosis; Mutation; Neoplasms; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Time Factors; Tumor Suppressor Proteins | 2008 |
Resveratrol protects against oxidative injury induced by H2O2 in acute hippocampal slice preparations from Wistar rats.
Topics: Animals; Antioxidants; Astrocytes; Cell Membrane Permeability; Extracellular Signal-Regulated MAP Kinases; Glutamic Acid; Glutathione; Hippocampus; Hydrogen Peroxide; In Vitro Techniques; Lactic Acid; Nerve Growth Factors; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stilbenes | 2008 |
Targeted isolation and structure elucidation of stilbene glycosides from the bark of Lysidice brevicalyx Wei guided by biological and chemical screening.
Topics: Antioxidants; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fabaceae; Glucosides; Glycosides; Molecular Structure; Plant Bark; Resveratrol; Stilbenes | 2008 |
The role of surface receptor stimulation on the cytotoxicity of resveratrol to macrophages.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Culture Media; DNA Fragmentation; Lipopolysaccharides; Macrophages; Mice; Microscopy, Electron, Scanning; Nitrites; Receptors, Cell Surface; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Toll-Like Receptor 4 | 2008 |
Effect of frequency and duration of ultrasonication on the extraction efficiency of selected isoflavones and trans-resveratrol from peanuts (Arachis hypogaea).
Topics: Antioxidants; Arachis; Chromatography, High Pressure Liquid; Genistein; Isoflavones; Plant Extracts; Reference Standards; Resveratrol; Solvents; Stilbenes; Ultrasonics | 2009 |
Non-canonical autophagy: an exception or an underestimated form of autophagy?
Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Humans; Membrane Proteins; Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2008 |
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.
Topics: Acetylation; Animals; Cell Line, Transformed; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Fasting; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gluconeogenesis; Heterocyclic Compounds, 4 or More Rings; Humans; Liver; Male; Mice; Mice, Knockout; Nuclear Proteins; p300-CBP Transcription Factors; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors; Ubiquitin-Protein Ligases | 2008 |
Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Epigenesis, Genetic; Female; Genes, BRCA1; Germ-Line Mutation; Humans; Inhibitor of Apoptosis Proteins; Mammary Neoplasms, Experimental; Mice; Mice, Mutant Strains; Mice, Nude; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasm Proteins; Ovarian Neoplasms; Repressor Proteins; Resveratrol; RNA Interference; Sirtuin 1; Sirtuins; Stilbenes; Survivin | 2008 |
Resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction.
Topics: Administration, Oral; Animals; Calcium Channels, L-Type; Cardiac Pacing, Artificial; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography; KATP Channels; Male; Myocardial Infarction; Patch-Clamp Techniques; Phytoalexins; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Stilbenes; Survival Rate; Tachycardia, Ventricular; Telemetry; Terpenes; Time Factors; Ventricular Fibrillation; Ventricular Remodeling | 2008 |
Opposite effects of two resveratrol (trans-3,5,4'-trihydroxystilbene) tetramers, vitisin A and hopeaphenol, on apoptosis of myocytes isolated from adult rat heart.
Topics: Animals; Antioxidants; Apoptosis; Benzofurans; Calcium; Cytochromes c; Heart; Intracellular Membranes; Membrane Potentials; Mitochondria, Heart; Mitochondrial Swelling; Myocardium; Myocytes, Cardiac; Phenols; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
[Relationship between apoptotic effect of Resveratrol on KG-1 cells and expression of bcl-2/bax].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Humans; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2008 |
Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet.
Topics: Animals; Antioxidants; Body Weight; Diet, Atherogenic; Eating; Fatty Liver; Gene Expression; Lipid Metabolism; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Organ Size; Resveratrol; Stilbenes | 2008 |
Neuroprotective effect of resveratrol on 6-OHDA-induced Parkinson's disease in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2008 |
Cardioprotective and antiarrhythmic effects of resveratrol--a modern perspective on an old treatment: editorial to "resveratrol attenuates ventricular arrhythmias and improves the long-term survival in rats with myocardial infarction" by Chen et al.
Topics: Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Drug Therapy; Humans; Myocardial Infarction; Rats; Resveratrol; Stilbenes; Survival Rate; Time Factors; Ventricular Fibrillation; Ventricular Flutter | 2008 |
Resveratrol regulates the expression of NHE-1 by repressing its promoter activity: critical involvement of intracellular H2O2 and caspases 3 and 6 in the absence of cell death.
Topics: Animals; Anticarcinogenic Agents; Caspase 3; Caspase 6; Cell Death; Cell Line; Down-Regulation; Gene Expression Regulation; Hydrogen Peroxide; Mice; Promoter Regions, Genetic; Rats; Resveratrol; Signal Transduction; Sodium-Hydrogen Exchangers; Stilbenes | 2009 |
The design, synthesis, and anti-tumor mechanism study of N-phosphoryl amino acid modified resveratrol analogues.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspases; DNA Fragmentation; HeLa Cells; Humans; Inhibitory Concentration 50; K562 Cells; Mitochondria; Mitochondrial Membranes; Phosphoamino Acids; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2008 |
Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging.
Topics: Aging; Animals; Calcium; Chlorocebus aethiops; Cognition Disorders; COS Cells; Diet; Dopamine; Male; Oxidative Stress; Rats; Rats, Inbred F344; Receptor, Muscarinic M1; Resveratrol; Stilbenes; Transfection | 2008 |
Resveratrol protects bone marrow mesenchymal stem cell derived chondrocytes cultured on chitosan-gelatin scaffolds from the inhibitory effect of interleukin-1beta.
Topics: Animals; Antioxidants; Bone Marrow Cells; Cells, Cultured; Chitosan; Chondrocytes; Culture Media; Gelatin; Interleukin-1beta; Mesenchymal Stem Cells; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tissue Scaffolds | 2008 |
Crystal and molecular structure of piceatannol; scavenging features of resveratrol and piceatannol on hydroxyl and peroxyl radicals and docking with transthyretin.
Topics: Crystallization; Crystallography, X-Ray; Free Radical Scavengers; Hydrogen Bonding; Hydroxyl Radical; Molecular Structure; Peroxides; Prealbumin; Resveratrol; Stilbenes | 2008 |
A theoretical antioxidant pharmacophore for resveratrol.
Topics: Antioxidants; Electrons; Free Radicals; Resveratrol; Stilbenes; Thermodynamics | 2009 |
Resveratrol ameliorates hepatic injury via the mitochondrial pathway in rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytochromes c; Disease Models, Animal; Gene Expression Regulation; Liver; Male; Mitochondria, Liver; Pancreatitis; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Severity of Illness Index; Stilbenes | 2008 |
Collisionally induced fragmentation of [M-H](-) species of resveratrol and piceatannol investigated by deuterium labelling and accurate mass measurements.
Topics: Deuterium; Deuterium Exchange Measurement; Molecular Weight; Phytoalexins; Resveratrol; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Terpenes | 2008 |
Direct determination of polydatin and its metabolite in rat excrement samples by high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Feces; Gastrointestinal Tract; Glucosides; Indicators and Reagents; Mass Spectrometry; Rats; Rats, Wistar; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2008 |
Structure-activity relationship and mechanism of the tocopherol-regenerating activity of resveratrol and its analogues.
Topics: Antioxidants; Kinetics; Oxidation-Reduction; Resveratrol; Stilbenes; Structure-Activity Relationship; Tocopherols | 2008 |
Resveratrol and 4-hydroxynonenal act in concert to increase glutamate cysteine ligase expression and glutathione in human bronchial epithelial cells.
Topics: Aldehydes; Antioxidants; Bronchi; Cell Line; Drug Synergism; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Humans; NF-E2-Related Factor 2; Respiratory Mucosa; Resveratrol; Stilbenes | 2009 |
LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Cell Movement; Cell Survival; Chromatin Immunoprecipitation; Female; Gene Expression; Humans; Imines; Immunohistochemistry; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Phosphorylation; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Stilbenes; Xenograft Model Antitumor Assays | 2008 |
Structure-efficiency relationship in derivatives of stilbene. Comparison of resveratrol, pinosylvin and pterostilbene.
Topics: Adenosine Triphosphate; Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Humans; Luminescence; Neutrophils; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship | 2008 |
Induction of cytochromes P450 in small intestine by chemopreventive compounds.
Topics: Allyl Compounds; Animals; Anticarcinogenic Agents; beta-Naphthoflavone; Blotting, Western; Curcumin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Flavonoids; Intestine, Small; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfides; Xenobiotics | 2008 |
Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Squamous Cell; Caspases; Cell Line, Tumor; Humans; Janus Kinases; Membrane Potential, Mitochondrial; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; STAT1 Transcription Factor; Stilbenes; Transcription, Genetic | 2008 |
Porcine sirtuin 1 gene clone, expression pattern, and regulation by resveratrol.
Topics: Adipocytes; Age Factors; Amino Acid Sequence; Animals; Antioxidants; Base Sequence; Cloning, Molecular; Female; Gene Expression Profiling; Gene Expression Regulation; Molecular Sequence Data; Phylogeny; Resveratrol; RNA, Messenger; Sequence Alignment; Sirtuins; Stilbenes; Swine | 2009 |
Resveratrol regulates circadian clock genes in Rat-1 fibroblast cells.
Topics: Animals; Cell Line; Cell Survival; Circadian Rhythm; Fibroblasts; Gene Expression Regulation; Humans; Rats; Resveratrol; Stilbenes; Time Factors | 2008 |
Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1.
Topics: Animals; Antioxidants; Cell Line; Dinoprostone; Flavonoids; Humans; Mice; Phenols; Polyphenols; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Up-Regulation | 2008 |
Regio- and stereoselective biomimetic synthesis of oligostilbenoid dimers from resveratrol analogues: influence of the solvent, oxidant, and substitution.
Topics: Biomimetics; Catalysis; Dimerization; Flavonoids; Molecular Structure; Oxidants; Phenols; Polyphenols; Resveratrol; Solvents; Stereoisomerism; Stilbenes | 2008 |
Overexpression of SIRT1 protects pancreatic beta-cells against cytokine toxicity by suppressing the nuclear factor-kappaB signaling pathway.
Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Cytokines; Electrophoretic Mobility Shift Assay; Female; Genetic Vectors; Humans; Insulin-Secreting Cells; Interferon-gamma; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Mice, Inbred NOD; NF-kappa B; Nitric Oxide Synthase Type II; Rats; Resveratrol; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
The action of resveratrol, a phytoestrogen found in grapes, on the intervertebral disc.
Topics: ADAM Proteins; ADAMTS4 Protein; Animals; Cartilage, Articular; Cattle; Cell Proliferation; Cell Survival; Cells, Cultured; DNA Replication; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Fruit; Gene Expression Regulation, Enzymologic; Homeostasis; Interleukin-1; Intervertebral Disc; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Phytoestrogens; Procollagen N-Endopeptidase; Proteoglycans; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Vitis | 2008 |
Th1/Th2 cytokine balance as a determinant of acetaminophen-induced liver injury.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Drug Evaluation, Preclinical; Glutathione; Interleukin-6; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Th1 Cells; Th2 Cells; Tumor Necrosis Factor-alpha | 2009 |
Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4(-) IFN-gamma+ cells, and decreased macrophage IL-6 expression.
Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; CD4 Antigens; Diet; Encephalomyelitis, Autoimmune, Experimental; Female; Flow Cytometry; Freund's Adjuvant; Immunotherapy, Adoptive; Interferon-gamma; Interleukin-10; Interleukin-17; Interleukin-6; Macrophages; Mice; Monocytes; Myelin Proteolipid Protein; Peptide Fragments; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Stilbenes; T-Lymphocytes | 2009 |
Protective effect of dietary phytochemicals against arsenite induced genotoxicity in mammalian V79 cells.
Topics: Animals; Arsenites; Capsaicin; Cell Line; Comet Assay; Cricetinae; Cricetulus; Curcumin; Diet; DNA Damage; Ellagic Acid; Flavonoids; Mutagens; Reactive Oxygen Species; Resveratrol; Stilbenes | 2008 |
[Protective effect of resveratrol on intestinal mucosal barrier in rats with severe acute pancreatitis].
Topics: Animals; Apoptosis; Bacterial Translocation; Intestinal Mucosa; Male; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain Ischemia; Cell Death; Cytochromes c; DNA Fragmentation; Glucosephosphate Dehydrogenase; Glutathione; Hippocampus; HSP70 Heat-Shock Proteins; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Lactate Dehydrogenases; Lipid Peroxidation; Male; Metallothionein; Mitochondria; Neuroprotective Agents; Protein Carbonylation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells.
Topics: Animals; Apoptosis; Biomarkers; Dose-Response Relationship, Drug; Glaucoma; Hydrogen Peroxide; Inflammation; Oxidative Stress; Oxygen; Reactive Oxygen Species; Resveratrol; Stilbenes; Swine; Trabecular Meshwork | 2009 |
Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice.
Topics: Animals; Apolipoprotein A-I; Cystathionine beta-Synthase; Dietary Supplements; Gene Expression Regulation; Genotype; Hyperhomocysteinemia; Lipid Metabolism; Liver; Mice; Phosphatidylcholine-Sterol O-Acyltransferase; Resveratrol; S-Adenosylhomocysteine; S-Adenosylmethionine; Scavenger Receptors, Class B; Stilbenes | 2009 |
Protective effect of resveratrol on acute endotoxemia-induced nephrotoxicity in rat through nitric oxide independent mechanism.
Topics: Animals; Endotoxemia; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Lipopolysaccharides; Male; Nitric Oxide; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2008 |
Effects of resveratrol on the pharmacokinetics of diltiazem and its major metabolite, desacetyldiltiazem, in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Antioxidants; Area Under Curve; Biological Availability; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2008 |
trans-Resveratrol inhibits H2O2-induced adenocarcinoma gastric cells proliferation via inactivation of MEK1/2-ERK1/2-c-Jun signalling axis.
Topics: Adenocarcinoma; Blotting, Western; Cell Proliferation; Enzyme Activation; Humans; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes; Stomach Neoplasms | 2009 |
Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Ascorbic Acid; Benzothiazoles; Blotting, Western; Brain; Cerebral Ventricles; Cysteine; Dietary Supplements; Female; Glutathione; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Transgenic; Plaque, Amyloid; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; tau Proteins; Thiazoles; Transcription Factors; Tumor Suppressor Protein p53 | 2009 |
Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes.
Topics: Adipocytes; Animals; Bucladesine; Carbon Dioxide; Cell Separation; Cell Survival; Cyclic AMP; Epinephrine; Fatty Acids; Glycerol; Insulin; Isoquinolines; Lactic Acid; Lipogenesis; Lipolysis; Male; Phenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfonamides | 2009 |
Phenylalanine ammonia-lyase and stilbene synthase gene expression in rolB transgenic cell cultures of Vitis amurensis.
Topics: Acyltransferases; Amino Acid Sequence; Bacterial Proteins; beta-Glucosidase; Cells, Cultured; Gene Expression Regulation, Plant; Molecular Sequence Data; Multigene Family; Phenylalanine Ammonia-Lyase; Plant Proteins; Plants, Genetically Modified; Resveratrol; Sequence Alignment; Stilbenes; Vitis | 2009 |
Resveratrol and large-conductance calcium-activated potassium channels in the protection of human retinal pigment epithelial cells.
Topics: Antioxidants; Cells, Cultured; Cytoprotection; Humans; Hydrogen Peroxide; Large-Conductance Calcium-Activated Potassium Channels; Phagocytosis; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2008 |
Combined effects of genistein, quercetin, and resveratrol in human and 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Antioxidants; Apoptosis; Cells, Cultured; Drug Synergism; Drug Therapy, Combination; Female; Genistein; Glycerolphosphate Dehydrogenase; Humans; Lipids; Mice; Obesity; Phytoestrogens; Quercetin; Resveratrol; Stilbenes | 2008 |
Resveratrol treatment in mice does not elicit the bradycardia and hypothermia associated with calorie restriction.
Topics: Animals; Anti-Obesity Agents; Bradycardia; Caloric Restriction; Exercise Test; Hypothermia; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Physical Endurance; Random Allocation; Resveratrol; Stilbenes; Time Factors | 2009 |
Resveratrol protects cardiomyocytes from hypoxia-induced apoptosis through the SIRT1-FoxO1 pathway.
Topics: Animals; Antioxidants; Apoptosis; Cell Hypoxia; Cells, Cultured; Cytoprotection; Forkhead Transcription Factors; Myocardial Ischemia; Myocytes, Cardiac; Nerve Tissue Proteins; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Inhibitory effect of glutamate release from rat cerebrocortical nerve terminals by resveratrol.
Topics: 4-Aminopyridine; Animals; Antioxidants; Calcium; Calcium Channel Blockers; Cerebral Cortex; Chelating Agents; Cytosol; Enzyme Activation; Exocytosis; Glutamic Acid; Male; Membrane Potentials; Mitogen-Activated Protein Kinases; Nerve Endings; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Synaptosomes; Vesicular Transport Proteins | 2009 |
Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Administration, Oral; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Evaluation, Preclinical; Fructose-Bisphosphatase; Gliclazide; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glycogen Phosphorylase; Glycogen Synthase; Hexokinase; Hypoglycemic Agents; Kidney; L-Lactate Dehydrogenase; Liver; Male; Niacinamide; Pyruvate Kinase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2009 |
Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore.
Topics: Aldehyde Reductase; Animals; Antioxidants; Calcium; Cyclosporine; Deoxyglucose; Disease Models, Animal; Glutathione; Humans; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardial Reperfusion Injury; Myocardium; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
[Antileukemic mechanism of resveratrol in vitro and in mice bearing L1210-tumor].
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Female; Humans; Interleukin-6; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Messenger; STAT3 Transcription Factor; Stilbenes | 2008 |
Improved antiulcer and anticancer properties of a trans-resveratrol analog in mice.
Topics: Animals; Anti-Ulcer Agents; Antineoplastic Agents; Cyclooxygenase 1; Cyclooxygenase 2; Indomethacin; Male; Mice; Misoprostol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Stomach; Stomach Ulcer; Wound Healing | 2009 |
Trans-resveratrol alone and hydroxystilbenes of rhubarb (Rheum rhaponticum L.) root reduce liver damage induced by chronic ethanol administration: a comparative study in mice.
Topics: Animals; Chemical and Drug Induced Liver Injury; Ethanol; Fatty Acids, Unsaturated; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Plant Extracts; Plant Roots; Resveratrol; Rheum; Stilbenes | 2009 |
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cell Line; Glucose; Humans; Muscles; Niacinamide; Oxidation-Reduction; Phosphorylation; Pyruvic Acid; Quercetin; Rats; Resveratrol; Serine; Sirtuin 1; Sirtuins; Stilbenes; Threonine | 2009 |
Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Equol; Estrogen Receptor alpha; Isoflavones; Male; Nitriles; Phenols; Phytoestrogens; Propionates; Pyrazoles; Rats; Rats, Long-Evans; Rats, Wistar; Resveratrol; Stilbenes; Testosterone | 2009 |
Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol.
Topics: Aging; Animals; Apoptosis; Cardiotonic Agents; Forkhead Transcription Factors; In Situ Nick-End Labeling; Myocytes, Cardiac; Nerve Tissue Proteins; Nicotinamide Phosphoribosyltransferase; Oncogene Protein v-akt; Phenylethyl Alcohol; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Transcriptional Activation; Wine | 2009 |
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Body Weight; Cell Proliferation; Diethylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Drug Screening Assays, Antitumor; Eating; Female; Immunohistochemistry; Liver Neoplasms, Experimental; Organ Size; Phenobarbital; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2009 |
Nitric oxide initiates progression of human melanoma via a feedback loop mediated by apurinic/apyrimidinic endonuclease-1/redox factor-1, which is inhibited by resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Disease Progression; DNA-(Apurinic or Apyrimidinic Site) Lyase; Feedback, Physiological; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Models, Biological; Neoplasm Metastasis; Nitric Oxide; Resveratrol; Stilbenes; Transcription Factor AP-1 | 2008 |
alphavbeta3 Integrin-dependent antiangiogenic activity of resveratrol stereoisomers.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Cattle; Chick Embryo; Endothelial Cells; Female; Humans; Integrin alphaVbeta3; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neovascularization, Pathologic; Resveratrol; Stereoisomerism; Stilbenes | 2008 |
Rapid determination of trans-resveratrol in red wine by solid-phase microextraction with on-fiber derivatization and multidimensional gas chromatography-mass spectrometry.
Topics: Gas Chromatography-Mass Spectrometry; Linear Models; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Solid Phase Microextraction; Stereoisomerism; Stilbenes; Temperature; Time Factors; Wine | 2009 |
A rapid HPLC method for the quantification of 3,5,4'-trimethoxy-trans-stilbene (TMS) in rat plasma and its application in pharmacokinetic study.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; beta-Cyclodextrins; Biological Availability; Calibration; Chromatography, High Pressure Liquid; Guidelines as Topic; Half-Life; Male; Metabolic Clearance Rate; Molecular Structure; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results; Resveratrol; Solvents; Spectrophotometry, Ultraviolet; Stilbenes; Time Factors | 2009 |
Resveratrol attenuates oxidative stress and histological alterations induced by liver ischemia/reperfusion in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Disease Models, Animal; Glutathione Peroxidase; Ligation; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase | 2008 |
Directed evolution of estrogen receptor proteins with altered ligand-binding specificities.
Topics: Directed Molecular Evolution; Estradiol; Estrogen Receptor alpha; Histone Acetyltransferases; Humans; Ligands; Mutagenesis, Site-Directed; Mutation; Nuclear Receptor Coactivator 1; Protein Engineering; Resveratrol; Stilbenes; Transcription Factors | 2009 |
Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.
Topics: Animals; Calcium Channels; Chloride Channels; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Nifedipine; Patch-Clamp Techniques; Peptides; Rats; Resveratrol; Solutions; Stilbenes; Tolbutamide | 2008 |
Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats.
Topics: Adipose Tissue; Animals; Blood Pressure; Disease Models, Animal; Drug Administration Schedule; Humans; Hypertension; Lipid Metabolism; Male; Metabolic Syndrome; Obesity; Random Allocation; Rats; Rats, Zucker; Resveratrol; Stilbenes | 2009 |
Pallidol, a resveratrol dimer from red wine, is a selective singlet oxygen quencher.
Topics: Dimerization; Free Radical Scavengers; Polycyclic Compounds; Resveratrol; Singlet Oxygen; Stilbenes; Wine | 2009 |
Alteration of xenobiotic metabolizing enzymes by resveratrol in liver and lung of CD1 mice.
Topics: Animals; Anticarcinogenic Agents; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glucuronosyltransferase; Glutathione Transferase; Injections, Intraperitoneal; Liver; Lung; Male; Metabolic Detoxication, Phase II; Mice; Mice, Inbred Strains; Oxidoreductases; Resveratrol; Stilbenes; Transferases | 2009 |
Resveratrol inhibits the mTOR mitogenic signaling evoked by oxidized LDL in smooth muscle cells.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Atherosclerosis; Cell Proliferation; Flavonoids; Humans; Lipoproteins, LDL; Myocytes, Smooth Muscle; Phenols; Phosphatidylinositol 3-Kinases; Polyphenols; Protein Kinases; Rabbits; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2009 |
[Effects of resveratrol on the release of Glu and Gln in cultured rat astrocytes with stretch injury].
Topics: Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Glutamine; Glutathione; L-Lactate Dehydrogenase; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Mechanical | 2008 |
Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Binding, Competitive; Biological Transport, Active; Cell Line; Enterocytes; Humans; Intestinal Mucosa; Male; Membrane Proteins; Mice; Mice, Transgenic; Resveratrol; Spodoptera; Stilbenes; Tissue Distribution; Transport Vesicles | 2009 |
Production of stilbenoids and phenolic acids by the peanut plant at early stages of growth.
Topics: Antioxidants; Arachis; Chromatography, High Pressure Liquid; Cinnamates; Hydrolysis; Hydroxybenzoates; Magnetic Resonance Spectroscopy; Phytoalexins; Plant Roots; Resveratrol; Seedlings; Seeds; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Terpenes | 2006 |
Mechanism for resveratrol-induced cardioprotection against reperfusion injury involves glycogen synthase kinase 3beta and mitochondrial permeability transition pore.
Topics: Animals; Blotting, Western; Cardiotonic Agents; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoprecipitation; In Vitro Techniques; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Resveratrol inhibits MMP-9 expression by up-regulating PPAR alpha expression in an oxygen glucose deprivation-exposed neuron model.
Topics: Animals; Antioxidants; Cells, Cultured; Enzyme Inhibitors; Hypoxia-Ischemia, Brain; Indoles; Lipoxygenase Inhibitors; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neurons; PPAR alpha; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2009 |
The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents; Antioxidants; Azaserine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Humans; Hyperglycemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Oxidative Stress; Rats; Rats, Inbred WKY; Resveratrol; Stilbenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents | 2009 |
Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells.
Topics: Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Chemoprevention; Cytochrome P-450 CYP1B1; DNA Adducts; Estradiol; Gene Expression Regulation, Enzymologic; Humans; Models, Biological; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polychlorinated Dibenzodioxins; Protein Transport; Resveratrol; Stilbenes | 2008 |
Resveratrol enhances cell-mediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Female; Immunity, Cellular; Mice; Mice, Inbred C3H; Mice, Knockout; Neovascularization, Pathologic; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Stilbenes; Toll-Like Receptor 4 | 2009 |
Total synthesis of diverse carbogenic complexity within the resveratrol class from a common building block.
Topics: Indans; Phenols; Resveratrol; Stilbenes | 2009 |
Endoplasmic reticulum stress-induced cell death in dopaminergic cells: effect of resveratrol.
Topics: Animals; Antioxidants; Caspases; Cell Death; Cell Line; Cinnamates; Dopamine; Endoplasmic Reticulum; Humans; Oxidative Stress; Proteasome Endopeptidase Complex; Rats; Resveratrol; RNA Interference; Stilbenes; Thiourea | 2009 |
Simple spectrophotometric assessment of the trans-/cis-resveratrol ratio in aqueous solutions.
Topics: Isomerism; Resveratrol; Solubility; Solvents; Spectrophotometry, Ultraviolet; Stilbenes; Ultraviolet Rays; Water | 2009 |
Elevation of oxidative-damage biomarkers during aging in F2 hybrid mice: protection by chronic oral intake of resveratrol.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aging; Animals; Biomarkers; Breeding; Deoxyguanosine; DNA Damage; Kidney; Mice; Myocardium; Organ Specificity; Oxidative Stress; Prostaglandins A; Protein Carbonylation; Resveratrol; Stilbenes | 2009 |
Cathepsin L mediates resveratrol-induced autophagy and apoptotic cell death in cervical cancer cells.
Topics: Apoptosis; Autophagy; Caspase 3; Cathepsin L; Cathepsins; Cell Line, Tumor; Cell Proliferation; Cysteine Endopeptidases; Cytochromes c; Cytosol; Enzyme Activation; Extracellular Space; Female; Humans; Intracellular Membranes; Iron; Lysosomes; Models, Biological; Permeability; Protein Transport; Resveratrol; Stilbenes; Uterine Cervical Neoplasms | 2009 |
Resveratrol attenuates 1,2-dimethylhydrazine (DMH) induced glycoconjugate abnormalities during various stages of colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Disease Models, Animal; Fucose; Glycoconjugates; Hexosamines; Male; Rats; Rats, Wistar; Resveratrol; Sialic Acids; Stilbenes | 2009 |
Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol.
Topics: Amyloid; Animals; Antioxidants; Cell Line; Diabetes Mellitus, Type 2; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Molecular Structure; Protein Conformation; Rats; Resveratrol; Stilbenes; Wine | 2009 |
Effects of resveratrol on nucleotide degrading enzymes in streptozotocin-induced diabetic rats.
Topics: 5'-Nucleotidase; Adenosine Deaminase; Animals; Blood Platelets; Diabetes Mellitus, Experimental; Male; Platelet Aggregation Inhibitors; Pyrophosphatases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2009 |
Resveratrol metabolites in urine as a biomarker of wine intake in free-living subjects: The PREDIMED Study.
Topics: Aged; Aged, 80 and over; Alcohol Drinking; Biomarkers; Chromatography, Liquid; Cohort Studies; Female; Humans; Male; Middle Aged; Resveratrol; Sensitivity and Specificity; Stilbenes; Surveys and Questionnaires; Tandem Mass Spectrometry; Wine | 2009 |
Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage.
Topics: Animals; Antioxidants; Blood Pressure; Catalase; Doxorubicin; Glutathione; Heart Diseases; Heart Rate; Luminescent Measurements; Malondialdehyde; Myocardium; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2009 |
Low responsiveness of grapevine flowers and berries at fruit set to UV-C irradiation.
Topics: Chitinases; Flowers; Fruit; Gene Expression Regulation, Plant; Genes, Plant; Resveratrol; RNA, Messenger; Stilbenes; Ultraviolet Rays; Vitis | 2009 |
A new specific BACE-1 inhibitor from the stembark extract of Vitis vinifera.
Topics: Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Baculoviridae; Enzyme Inhibitors; Molecular Structure; Plant Bark; Plant Extracts; Plant Stems; Resveratrol; Stilbenes; Vitis | 2009 |
Anti-inflammatory and anti-asthmatic effects of resveratrol, a polyphenolic stilbene, in a mouse model of allergic asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Eosinophilia; Female; Goblet Cells; Immunoglobulin E; Immunoglobulin G; Interleukin-4; Interleukin-5; Lung; Mice; Mice, Inbred BALB C; Mucus; Ovalbumin; Resveratrol; Stilbenes | 2009 |
The effects of resveratrol and tannic acid on apoptosis in colon adenocarcinoma cell line.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Cell Line, Tumor; Colonic Neoplasms; Fas-Associated Death Domain Protein; Humans; Resveratrol; Stilbenes; Tannins | 2009 |
Histone deacetylase inhibition activity and molecular docking of (e )-resveratrol: its therapeutic potential in spinal muscular atrophy.
Topics: Cell Line; Computer Simulation; Enzyme Inhibitors; Fibroblasts; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Muscular Atrophy, Spinal; Resveratrol; SMN Complex Proteins; Stilbenes; Structure-Activity Relationship; Survival of Motor Neuron 2 Protein; Thermodynamics | 2009 |
High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research.
Topics: Aging; Animals; Antioxidants; Cold Temperature; Fishes; Genetic Markers; Genome; Longevity; Models, Animal; Phylogeny; Resveratrol; Stilbenes; Tandem Repeat Sequences | 2009 |
Effect of resveratrol on the pharmacokinetics of oral and intravenous nicardipine in rats: possible role of P-glycoprotein inhibition by resveratrol.
Topics: Administration, Oral; Animals; Antioxidants; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Fluorescent Dyes; Half-Life; Humans; Injections, Intravenous; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Resveratrol; Rhodamine 123; Stilbenes | 2009 |
Protective effect of resveratrol against kainate-induced temporal lobe epilepsy in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Blotting, Western; Cell Death; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; In Vitro Techniques; Kainic Acid; Male; Mossy Fibers, Hippocampal; Neurons; Rats; Rats, Wistar; Receptors, Kainic Acid; Resveratrol; Seizures; Stilbenes | 2009 |
Trans-resveratrol-mediated inhibition of beta-oestradiol conjugation in MCF-7 cells stably expressing human sulfotransferases SULT1A1 or SULT1E1, and human liver microsomes.
Topics: Arylsulfotransferase; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogen Antagonists; Humans; Microsomes, Liver; Resveratrol; Stilbenes; Sulfotransferases | 2009 |
Evaluation of radiotherapy effect in resveratrol-treated medulloblastoma cancer stem-like cells.
Topics: Anticarcinogenic Agents; bcl-2-Associated X Protein; bcl-X Protein; Cell Proliferation; Cells, Cultured; Chemotherapy, Adjuvant; Humans; Intermediate Filament Proteins; Medulloblastoma; Neoplastic Stem Cells; Nerve Tissue Proteins; Nestin; Radiotherapy, Adjuvant; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2009 |
Inhibitory effects of polyphenol compounds on lipid peroxidation caused by antipsychotics (haloperidol and amisulpride) in human plasma in vitro.
Topics: Adult; Amisulpride; Antioxidants; Antipsychotic Agents; Female; Haloperidol; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Quercetin; Resveratrol; Stilbenes; Sulpiride; Thiobarbituric Acid Reactive Substances | 2010 |
Effect of a low dose of dietary resveratrol on colon microbiota, inflammation and tissue damage in a DSS-induced colitis rat model.
Topics: Animals; Anti-Inflammatory Agents; Colitis; Colon; Dextran Sulfate; Diet; Feces; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2009 |
[Authors' ideas, research and conflicts of interest].
Topics: Conflict of Interest; Drug Industry; Moral Obligations; Publishing; Resveratrol; Stilbenes | 2009 |
Generation of the human metabolite piceatannol from the anticancer-preventive agent resveratrol by bacterial cytochrome P450 BM3.
Topics: Anticarcinogenic Agents; Bacterial Proteins; Carbon Monoxide; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Kinetics; Mutagenesis, Site-Directed; Mutation; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Resveratrol; Stilbenes | 2009 |
Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Antioxidants; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cyclin A; DNA; Hydrogen Peroxide; Mice; Mitosis; Oxidants; Oxidation-Reduction; Protein Binding; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Caloric Restriction; DNA-Binding Proteins; Food Deprivation; Food, Formulated; Forkhead Transcription Factors; Gene Expression Regulation; Longevity; Protein Kinases; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors | 2009 |
Resveratrol promotes an inhibitory effect on the turbot scuticociliate parasite Philasterides dicentrarchi by mechanisms related to cellular detoxification.
Topics: Animals; Antioxidants; Antiprotozoal Agents; Apoptosis; Ciliophora; Dose-Response Relationship, Drug; Flatfishes; Mitochondria; Oxygen Consumption; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors | 2009 |
[Red red wine].
Topics: Antioxidants; Cardiovascular Diseases; Humans; Neurodegenerative Diseases; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Wine | 2009 |
4,4'-Dihydroxy-trans-stilbene, a resveratrol analogue, exhibited enhanced antioxidant activity and cytotoxicity.
Topics: Antioxidants; Cell Line, Tumor; Drug Screening Assays, Antitumor; Erythrocyte Membrane; Humans; Kinetics; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Stilbenes | 2009 |
Resveratrol inhibits fatty acid and triacylglycerol synthesis in rat hepatocytes.
Topics: Acetyl-CoA Carboxylase; Animals; Antioxidants; Cholesterol; Fatty Acids; Hepatocytes; Male; Rats; Rats, Wistar; Resveratrol; Statistics as Topic; Stilbenes; Triglycerides | 2009 |
Red wine triggers cell death and thioredoxin reductase inhibition: effects beyond resveratrol and SIRT1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Astrocytes; Cell Death; Cell Differentiation; Cell Line, Tumor; Immunohistochemistry; Neurons; Oxidative Stress; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stem Cells; Stilbenes; Thioredoxin-Disulfide Reductase; Wine | 2009 |
Dihydrostilbene derivatives from the Mongolian medicinal plant Scorzonera radiata.
Topics: Antioxidants; Biphenyl Compounds; Drugs, Chinese Herbal; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Picrates; Plants, Medicinal; Resveratrol; Scorzonera; Stilbenes | 2009 |
Antioxidant-based lead discovery for cancer chemoprevention: the case of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Cations, Divalent; Cell Survival; Copper; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; In Vitro Techniques; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; Oxidants; Reactive Oxygen Species; Resveratrol; Stilbenes; T-Lymphocytes | 2009 |
Prevention of ocular inflammation in endotoxin-induced uveitis with resveratrol by inhibiting oxidative damage and nuclear factor-kappaB activation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Antioxidants; Blotting, Western; Chemokine CCL2; Deoxyguanosine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Fluorescent Antibody Technique, Indirect; Inflammation; Injections, Intraperitoneal; Intercellular Adhesion Molecule-1; Leukocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Resveratrol; Retina; Retinal Pigment Epithelium; Retinal Vessels; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factor RelA; Uveitis | 2009 |
Attenuation of lung inflammation and pro-inflammatory cytokine production by resveratrol following trauma-hemorrhage.
Topics: Animals; Cytokines; Hemorrhage; Intercellular Adhesion Molecule-1; Male; Peroxidase; Pneumonia; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wounds and Injuries | 2008 |
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.
Topics: Animals; Caloric Restriction; Enzyme Activation; Gene Expression Profiling; Heterocyclic Compounds, 4 or More Rings; Mice; Microarray Analysis; Models, Genetic; Molecular Structure; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Optimizing the extraction of phenolic antioxidants from peanut skins using response surface methodology.
Topics: Antioxidants; Arachis; Ethanol; Gallic Acid; Phenols; Placental Lactogen; Reactive Oxygen Species; Resveratrol; Seeds; Solvents; Stilbenes | 2009 |
Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1-FOXO1 signaling pathway.
Topics: Animals; Caloric Restriction; Cell Line, Tumor; Cell Survival; Fatty Liver; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Hypolipidemic Agents; Mice; Models, Biological; Palmitic Acid; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Sterol Regulatory Element Binding Protein 1; Stilbenes; Triglycerides | 2009 |
Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Niacinamide; Osteosarcoma; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Enhanced resveratrol accumulation in rolB transgenic cultures of Vitis amurensis correlates with unusual changes in CDPK gene expression.
Topics: Bacterial Proteins; beta-Glucosidase; Chromatography, High Pressure Liquid; Gene Expression Regulation, Plant; Plants, Genetically Modified; Protein Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Vitis | 2009 |
Protective role of SIRT1 in diabetic vascular dysfunction.
Topics: Acetylation; Animals; Aorta; Cells, Cultured; Cellular Senescence; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Endothelium, Vascular; Enzyme Activators; Forkhead Transcription Factors; Glucose; Humans; Mice; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Time Factors; Transfection; Tumor Suppressor Protein p53 | 2009 |
Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons.
Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Male; Mice; Mice, Inbred C57BL; NAD; Neurons; Neuroprotective Agents; Neurotoxins; Niacinamide; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Resveratrol prevents the prohypertrophic effects of oxidative stress on LKB1.
Topics: Aldehydes; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Cardiomegaly; Cells, Cultured; Hypertension; Hypertrophy, Left Ventricular; Lipid Peroxidation; Myocytes, Cardiac; Oxidative Stress; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred SHR; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2009 |
Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes.
Topics: 1-Naphthylamine; Animals; Antioxidants; Diabetic Neuropathies; Male; Malondialdehyde; NAD; Naphthalimides; Neural Conduction; Neuralgia; Neuroprotective Agents; Oxidative Stress; Pain Measurement; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Quinolones; Rats; Rats, Sprague-Dawley; Resveratrol; Sciatic Nerve; Stilbenes | 2009 |
Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells.
Topics: Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Binding Sites; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; Cyclin B; Cyclin B1; G2 Phase; Humans; Microtubules; Models, Molecular; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Resveratrol; Stilbenes; Tubulin | 2009 |
Resveratrol inhibits foam cell formation via NADPH oxidase 1- mediated reactive oxygen species and monocyte chemotactic protein-1.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Enzyme Activation; Foam Cells; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Lipopolysaccharides; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes | 2009 |
Inhibition of mammary tumor growth and metastases to bone and liver by dietary grape polyphenols.
Topics: Animals; Apoptosis; Bone Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; NF-kappa B; Quercetin; Resveratrol; Stilbenes; Vitis | 2009 |
Resveratrol toxicity: effects on risk factors for atherosclerosis and hepatic oxidative stress in standard and high-fat diets.
Topics: Animals; Antioxidants; Atherosclerosis; Blood Glucose; Body Weight; Diet; Dietary Fats; Dietary Supplements; Glutathione; Lipid Peroxides; Lipids; Lipoproteins, LDL; Liver; Male; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Risk Factors; Stilbenes; Triglycerides; Wine | 2009 |
Role of SIRT1 in regulation of LPS- or two ethanol metabolites-induced TNF-alpha production in cultured macrophage cell lines.
Topics: Acetaldehyde; Acetates; Acetylation; Adiponectin; Animals; Benzamides; Cell Line; Enzyme Inhibitors; Ethanol; Kupffer Cells; Lipopolysaccharides; Liver Diseases, Alcoholic; Macrophages; Mice; Mutation; Naphthols; Rats; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Transcription Factor RelA; Transfection; Tumor Necrosis Factor-alpha | 2009 |
Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Male; NF-kappa B; Prostatic Neoplasms; Protein Subunits; Resveratrol; Signal Transduction; Stilbenes; Subcellular Fractions; Transcription Factor RelA | 2009 |
Anticancer effects of an oncolytic parvovirus combined with non-conventional therapeutics on pancreatic carcinoma cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Interactions; H-1 parvovirus; Humans; Norfloxacin; Oncolytic Viruses; Resveratrol; Stilbenes | 2009 |
Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats.
Topics: Acetylcholinesterase; Animals; Avoidance Learning; Behavior, Animal; Blood Glucose; Cholinesterase Inhibitors; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Memory; Memory Disorders; Random Allocation; Rats; Resveratrol; Stilbenes; Streptozocin | 2009 |
Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway.
Topics: Animals; Cardiotonic Agents; Cell Death; Cells, Cultured; Doxorubicin; Drug Evaluation, Preclinical; Heart Failure; Mitochondria, Heart; Myocytes, Cardiac; Niacinamide; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Structure-Activity Relationship | 2009 |
[Effect of resveratrol-induced FasL up-regulation on the apoptosis of pancreatic acinar cells in rats with severe acute pancreatitis].
Topics: Animals; Apoptosis; Fas Ligand Protein; Male; Pancreas, Exocrine; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Taurocholic Acid; Up-Regulation | 2009 |
Caveolin-1 enhances resveratrol-mediated cytotoxicity and transport in a hepatocellular carcinoma model.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Carcinoma, Hepatocellular; Caveolin 1; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Drug Synergism; Endocytosis; Genes, Reporter; Humans; Liver Neoplasms; Mice; Mice, Nude; Resveratrol; Sequence Deletion; Stilbenes; Transfection | 2009 |
Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG.
Topics: Anticarcinogenic Agents; Catechin; Endometrial Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2009 |
Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice.
Topics: Androgen Receptor Antagonists; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carrier Proteins; Cell Cycle; Cell Proliferation; Curcumin; Cyclin D1; Disease Progression; Drug Carriers; Drug Delivery Systems; Incidence; Liposomes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphotransferases (Alcohol Group Acceptor); Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Androgen; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2009 |
NADPH oxidases 1 and 4 mediate cellular senescence induced by resveratrol in human endothelial cells.
Topics: Cell Cycle; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Endothelial Cells; Humans; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Resveratrol; S Phase; Stilbenes; Structure-Activity Relationship | 2009 |
Differential effects of several phytochemicals and their derivatives on murine keratinocytes in vitro and in vivo: implications for skin cancer prevention.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Carotenoids; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Ellagic Acid; Female; Free Radical Scavengers; Free Radicals; Genes, ras; Keratinocytes; Lycopene; Mice; Mutation; Plant Extracts; Proto-Oncogene Proteins p21(ras); Resveratrol; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid; Vitis | 2009 |
Resveratrol inhibits tumor cell adhesion to endothelial cells by blocking ICAM-1 expression.
Topics: Cell Adhesion; Dose-Response Relationship, Drug; Endothelial Cells; Fibrosarcoma; Humans; Intercellular Adhesion Molecule-1; NF-kappa B; Resveratrol; RNA, Small Interfering; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Effects of resveratrol analogs on cell cycle progression, cell cycle associated proteins and 5fluoro-uracil sensitivity in human derived colon cancer cells.
Topics: Antimetabolites, Antineoplastic; Benzofurans; Blotting, Western; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Flow Cytometry; Fluorescent Antibody Technique; Fluorouracil; Humans; Immunoenzyme Techniques; Immunoprecipitation; Phenols; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2009 |
Phytoalexin-enriched functional foods.
Topics: Anti-Inflammatory Agents; Anticholesteremic Agents; Antioxidants; Catechin; Fabaceae; Fermentation; Food, Fortified; Food, Organic; Fruit; Health Promotion; Isoflavones; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes; Tea; Terpenes; Vitis; Wine | 2009 |
Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol.
Topics: Amyloid; Animals; Cell Line; Cell Membrane; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Membrane Lipids; Microscopy, Fluorescence; Resveratrol; Stilbenes | 2009 |
"Resveratrol metabolites in urine as biomarker of wine intake in free-living subjects: The PREDIMED Study".
Topics: Alcohol Drinking; Biomarkers; Humans; Resveratrol; Stilbenes; Surveys and Questionnaires; Wine | 2009 |
Resveratrol attenuates C5a-induced inflammatory responses in vitro and in vivo by inhibiting phospholipase D and sphingosine kinase activities.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport, Active; Cell Degranulation; Cell Membrane; Chemokines; Chemotaxis, Leukocyte; Complement C5a; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; In Vitro Techniques; Inflammation; Male; Mice; Mice, Inbred BALB C; Neutrophils; NF-kappa B; Peritonitis; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Respiratory Burst; Resveratrol; Stilbenes | 2009 |
Antitumor activity of resveratrol and its sulfated metabolites against human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes | 2009 |
Biphasic activity of resveratrol on indomethacin-induced gastric ulcers.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Cyclooxygenase 1; Indomethacin; Male; Membrane Proteins; Mice; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes; Stomach Ulcer | 2009 |
In vitro inhibition of rat CYP1A1 and CYP1A2 by piceatannol, a hydroxylated metabolite of trans-resveratrol.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2007 |
Heme oxygenase-derived carbon monoxide restores vascular function in type 1 diabetes.
Topics: Adiponectin; Animals; Aorta; Carbon Monoxide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelial Cells; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Male; Organometallic Compounds; Protoporphyrins; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin | 2008 |
Resveratrol pretreatment protects rat brain from cerebral ischemic damage via a sirtuin 1-uncoupling protein 2 pathway.
Topics: Adenosine Triphosphate; Animals; Asphyxia; Benzamides; Brain Ischemia; Carotid Artery Diseases; Disease Models, Animal; Heart Arrest; Hippocampus; Hypotension; Ion Channels; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Naphthols; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Respiration; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Uncoupling Protein 2 | 2009 |
The dietary polyphenols trans-resveratrol and curcumin selectively bind human CB1 cannabinoid receptors with nanomolar affinities and function as antagonists/inverse agonists.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Curcumin; Female; Flavonoids; Humans; Male; Mice; Phenols; Polyphenols; Protein Binding; Receptor, Cannabinoid, CB1; Resveratrol; Stilbenes | 2009 |
Resveratrol-induced apoptosis and increased radiosensitivity in CD133-positive cells derived from atypical teratoid/rhabdoid tumor.
Topics: AC133 Antigen; Animals; Antigens, CD; Antigens, Neoplasm; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Glycoproteins; Humans; Mice; Mice, Inbred BALB C; Mice, SCID; Peptides; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Rhabdoid Tumor; Stilbenes; Teratoma | 2009 |
Antiangiogenic resveratrol analogues by mild m-CPBA aromatic hydroxylation of 3,5-dimethoxystilbenes.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Chlorobenzoates; Endothelial Cells; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes; Swine | 2009 |
Effect of protonation and aggregation state of (E)-resveratrol on its hydroperoxidation by lipoxygenase.
Topics: Glycine max; Hydrogen-Ion Concentration; Kinetics; Lipoxygenase; Organic Chemistry Phenomena; Oxidation-Reduction; Plant Proteins; Resveratrol; Stilbenes | 2009 |
Piceatannol, a derivative of resveratrol, moderately slows I(Na) inactivation and exerts antiarrhythmic action in ischaemia-reperfused rat hearts.
Topics: Aconitine; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Electric Stimulation; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Free Radical Scavengers; Humans; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium Channel Agonists; Sodium Channel Blockers; Sodium Channels; Stilbenes | 2009 |
Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9.
Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins c-jun; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Stilbenes; Stomach Neoplasms; Transfection | 2009 |
Gene expression profiling in Ishikawa cells: a fingerprint for estrogen active compounds.
Topics: Benzhydryl Compounds; Cell Line, Tumor; Cluster Analysis; DDT; Diethylstilbestrol; Endocrine Disruptors; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Estrogens; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genistein; Humans; Oligonucleotide Array Sequence Analysis; Phenols; Phytoestrogens; Polymerase Chain Reaction; Receptors, Estrogen; Reproducibility of Results; Resveratrol; Risk Assessment; RNA, Messenger; Stilbenes; Time Factors; Zearalenone | 2009 |
Caspase mediated enhanced apoptotic action of cyclophosphamide- and resveratrol-treated MCF-7 cells.
Topics: Annexin A5; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorimetry; Cyclophosphamide; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Resveratrol; Stilbenes | 2009 |
Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Blotting, Northern; Blotting, Western; Body Weight; Cells, Cultured; DNA; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart Rate; Interleukin-6; Luciferases; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Rats; Resveratrol; Stilbenes; Vascular Diseases | 2009 |
[Effect of resveratrol on myocardial fibrosis in mice with chronic viral myocarditis].
Topics: Animals; Chronic Disease; Collagen Type I; Collagen Type II; Coxsackievirus Infections; Enterovirus B, Human; Fibrosis; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Peptide Fragments; Procollagen; Resveratrol; Stilbenes | 2009 |
Inhibition of ATPase activity of Escherichia coli ATP synthase by polyphenols.
Topics: ATP Synthetase Complexes; Escherichia coli; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Proton Pumps; Quercetin; Resveratrol; Stilbenes | 2009 |
Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes.
Topics: Antimutagenic Agents; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Line, Tumor; Cells, Cultured; Chromatin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Dioxins; DNA Primers; Enzyme Induction; Gene Expression Regulation; Humans; Immunoprecipitation; Receptors, Aryl Hydrocarbon; Resveratrol; RNA Polymerase II; Stilbenes | 2009 |
[Spectroscopic study on the interaction between resveratrol and human serum albumin].
Topics: Angiogenesis Inhibitors; Humans; Immunity; Resveratrol; Serum Albumin; Spectrum Analysis; Stilbenes | 2009 |
Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: potent cytotoxicity of resveratrol to normal cells.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Flavonoids; Flow Cytometry; In Vitro Techniques; Male; Phenols; Polyphenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thymus Gland | 2009 |
[The effect of COX-1 and COX-3 inhibitors on blood nitric oxide concentration].
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Female; Male; Membrane Proteins; Nitric Oxide; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Ceramides; Humans; Oxidoreductases; Resveratrol; Stilbenes; Stomach Neoplasms; Sulfides | 2009 |
Enhanced growth inhibition effect of resveratrol incorporated into biodegradable nanoparticles against glioma cells is mediated by the induction of intracellular reactive oxygen species levels.
Topics: Animals; Biodegradation, Environmental; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Glioma; Intracellular Space; Microscopy, Fluorescence; Nanoparticles; Particle Size; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Vitamin E | 2009 |
Resveratrol enhances ultraviolet B-induced cell death through nuclear factor-kappaB pathway in human epidermoid carcinoma A431 cells.
Topics: Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Inhibitor of Apoptosis Proteins; Lim Kinases; Microtubule-Associated Proteins; NF-kappa B; Phosphorylation; Radiation-Sensitizing Agents; Resveratrol; Skin Neoplasms; Stilbenes; Survivin; Ultraviolet Rays | 2009 |
Chemoprevention of metaplasia initiation and carcinogenic progression to esophageal adenocarcinoma by resveratrol supplementation.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Catalase; Disease Models, Animal; Disease Progression; Esophageal Neoplasms; Esophagus; Glutathione; Immunohistochemistry; In Situ Nick-End Labeling; Male; Metaplasia; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2009 |
Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin.
Topics: Animals; Cell Line; Cell Movement; Complex Mixtures; Enzyme Activation; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt; Quercetin; Resveratrol; Stilbenes; Transcription Factor AP-1; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation; Wine | 2009 |
Resveratrol and cancer prevention.
Topics: Anticarcinogenic Agents; Humans; Neoplasms; Resveratrol; Stilbenes | 2009 |
Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo-a-pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Liver; Mesenteric Arteries; Polychlorinated Dibenzodioxins; Prostaglandin-Endoperoxide Synthases; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Zebrafish | 2009 |
Quantification of trans-resveratrol and its metabolites in rat plasma and tissues by HPLC.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Tissue Distribution | 2010 |
Characterizing the effects of common UDP glucuronosyltransferase (UGT) 1A6 and UGT1A1 polymorphisms on cis- and trans-resveratrol glucuronidation.
Topics: Cell Line; Gene Frequency; Genotype; Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Microsomes, Liver; Phenotype; Polymorphism, Genetic; Resveratrol; Stilbenes; TATA Box; Tissue Banks; Transfection | 2009 |
Resveratrol inhibits Porphyromonas gingivalis lipopolysaccharide-induced endothelial adhesion molecule expression by suppressing NF-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents; Cell Adhesion; Dose-Response Relationship, Drug; Endothelial Cells; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; Leukocytes; Lipopolysaccharides; Male; NF-KappaB Inhibitor alpha; Phosphorylation; Porphyromonas gingivalis; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor RelA; Transcription, Genetic; U937 Cells; Vascular Cell Adhesion Molecule-1 | 2009 |
Inhibition of suicidal erythrocyte death by resveratrol.
Topics: Adenylate Kinase; Annexin A5; Antioxidants; Calcium; Cell Death; Chlorides; Cytosol; Energy Metabolism; Erythrocytes; Flow Cytometry; Humans; In Vitro Techniques; Resveratrol; Stilbenes | 2009 |
Solubilization of resveratrol in micellar solutions of different bile acids.
Topics: Animals; Bile Acids and Salts; Buffers; Cluster Analysis; Conductometry; Hemolysis; Micelles; Rabbits; Regression Analysis; Resveratrol; Solubility; Solutions; Stilbenes | 2009 |
Resveratrol ameliorates lung injury via inhibition of apoptosis in rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Apoptosis; Dexamethasone; Lung; Lung Injury; Mitochondrial Membranes; Mitochondrial Proteins; Oxygen; Pancreatitis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2009 |
Effects of resveratrol on H(2)O(2)-induced apoptosis and expression of SIRTs in H9c2 cells.
Topics: Animals; Apoptosis; Caspase 3; Cell Line; Gene Expression Regulation; Hydrogen Peroxide; Myocytes, Cardiac; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Calcium; Cell Line; Cyclooxygenase 2; Enzyme Activation; Humans; I-kappa B Kinase; Interleukin-6; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Attenuation of 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity by resveratrol: a comparative study with different routes of administration.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Fatty Liver; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Toxicity Tests; Wasting Syndrome | 2009 |
Two new resveratrol tetramers from Upuna borneensis.
Topics: Benzofurans; Dipterocarpaceae; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Plant Extracts; Plant Stems; Resveratrol; Stilbenes | 2009 |
A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.
Topics: Antioxidants; Coumarins; Drug Design; Humans; Inhibitory Concentration 50; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Resveratrol; Selegiline; Stilbenes; Structure-Activity Relationship | 2009 |
Mechanisms of resveratrol-induced platelet apoptosis.
Topics: Actins; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blood Platelets; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Survival; Cysteine Proteinase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Gelsolin; Humans; Hydroxyl Radical; Membrane Potential, Mitochondrial; Mitochondria; Oligopeptides; P-Selectin; Phosphatidylserines; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Transport; Resveratrol; Signal Transduction; Stilbenes; Time Factors | 2009 |
A novel resveratrol derivative, HS1793, overcomes the resistance conferred by Bcl-2 in human leukemic U937 cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Nucleus; Cell Survival; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Immunoprecipitation; Membrane Potential, Mitochondrial; Methylation; Mitochondria; Molecular Structure; Naphthols; Proto-Oncogene Proteins c-bcl-2; Resorcinols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; U937 Cells | 2009 |
Resveratrol induces mitochondrial biogenesis in endothelial cells.
Topics: Animals; Antioxidants; Aorta, Thoracic; Cells, Cultured; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Electron Transport; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Mice; Mitochondria; Nitric Oxide Synthase Type III; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Effect of proliferation, cell cycle, and Bcl-2s of MCF-7 cells by resveratrol.
Topics: Caspase 3; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Female; Humans; Molecular Structure; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2009 |
Butyrate-induced cell death and differentiation are associated with distinct patterns of ROS in HT29-derived human colon cancer cells.
Topics: Antioxidants; Apoptosis; Butyrates; Cell Adhesion; Cell Death; Cell Differentiation; Cell Division; Cyclosporine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; HT29 Cells; Humans; Hydrogen Peroxide; Immunosuppressive Agents; In Situ Nick-End Labeling; Isoquinolines; Necrosis; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
An in vitro screening cascade to identify neuroprotective antioxidants in ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Blood-Brain Barrier; Caffeic Acids; Cell Culture Techniques; Cell Line; Central Nervous System; Humans; Mice; Mice, Inbred C57BL; Motor Neurons; Mutation; Oxidative Stress; Resveratrol; Small Molecule Libraries; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Transgenes; Umbelliferones | 2009 |
Protective effect of resveratrol on markers of oxidative stress in human erythrocytes subjected to in vitro oxidative insult.
Topics: Antioxidants; Biomarkers; Cells, Cultured; Erythrocyte Membrane; Erythrocytes; Glutathione; Humans; Oxidative Stress; Resveratrol; Stilbenes; tert-Butylhydroperoxide | 2010 |
Mechanisms of apoptotic effects induced by resveratrol, dibenzoylmethane, and their analogues on human lung carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Chalcones; Humans; Lung Neoplasms; Resveratrol; Stilbenes | 2009 |
Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
Topics: Caspase 3; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; L-Lactate Dehydrogenase; Methylation; Models, Chemical; Neurons; Neurotoxins; Oxidopamine; Phosphorylation; Resveratrol; Stilbenes | 2010 |
Improvement of neovascularization capacity of bone marrow mononuclear cells from diabetic mice by ex vivo pretreatment with resveratrol.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Bone Marrow Cells; Capillaries; Diabetes Mellitus, Experimental; Heart Rate; Hindlimb; Ischemia; Laser-Doppler Flowmetry; Malondialdehyde; Mice; Mice, Inbred C57BL; Monocytes; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Oxidative Stress; Reactive Oxygen Species; Receptors, Vascular Endothelial Growth Factor; Regional Blood Flow; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Superoxide Dismutase; Vascular Endothelial Growth Factor A | 2009 |
[Study on Diels-Alder type adducts from stem barks of Morus yunanensis].
Topics: Anti-Inflammatory Agents; Antioxidants; Drugs, Chinese Herbal; Flavonoids; Morus; Plant Bark; Plant Extracts; Plant Stems; Resveratrol; Stilbenes | 2009 |
Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.
Topics: Anthraquinones; Chromatography; Chromatography, High Pressure Liquid; Emodin; Mass Spectrometry; Models, Biological; Peroxidases; Plant Leaves; Plant Physiological Phenomena; Plant Roots; Reactive Oxygen Species; Resveratrol; Solvents; Stilbenes; Time Factors | 2009 |
9-Fluorenylmethoxycarbonyl-labeled peptides as substrates in a capillary electrophoresis-based assay for sirtuin enzymes.
Topics: Electrophoresis, Capillary; Fluorenes; Indoles; Resveratrol; Sirtuin 1; Sirtuin 2; Sirtuins; Stilbenes | 2009 |
A glass of red wine to improve mitochondrial biogenesis? Novel mechanisms of resveratrol.
Topics: Antioxidants; Coronary Disease; Humans; Mitochondria; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Wine | 2009 |
Protective effects of resveratrol and quercetin against MPP+ -induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Biomarkers; Blotting, Western; Cell Nucleus; Cytochromes c; Dopamine; Fluorescent Antibody Technique; Gene Expression Regulation; Kinetics; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Protein Transport; Quercetin; Rats; Resveratrol; RNA, Messenger; Stilbenes | 2009 |
The phytostilbene resveratrol induces apoptosis in INS-1E rat insulinoma cells.
Topics: Animals; Apoptosis; Caspases; Cell Cycle; Cell Line, Tumor; Dactinomycin; Insulin; Insulin-Secreting Cells; Insulinoma; Pancreatic Neoplasms; Phosphatidylserines; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Stilbenes; Time Factors | 2009 |
At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence.
Topics: Cell Proliferation; Cellular Senescence; Cytostatic Agents; Enzyme Inhibitors; Fibroblasts; Humans; Hydrogen Peroxide; Phosphorylation; Protein Kinases; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2009 |
Radical-scavenging activity and mechanism of resveratrol-oriented analogues: influence of the solvent, radical, and substitution.
Topics: Acetates; Antioxidants; Ethanol; Free Radicals; Kinetics; Molecular Structure; Resveratrol; Solvents; Stilbenes; Structure-Activity Relationship | 2009 |
Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3beta pathway.
Topics: Apoptosis; Cell Line; Fatty Acids; Gene Expression; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 2 | 2009 |
Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2009 |
Protective and therapeutic effects of resveratrol on acetic acid-induced gastric ulcer.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Antioxidants; Female; Glutathione; Irritants; Lipid Peroxidation; Luminescence; Male; Malondialdehyde; Neutrophils; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stomach Ulcer | 2009 |
Regulatory role of Sirt1 on the gene expression of fatty acid-binding protein 3 in cultured porcine adipocytes.
Topics: Adipocytes; Animals; Cells, Cultured; Down-Regulation; Fatty Acid-Binding Proteins; Gene Expression Regulation; Gene Knockdown Techniques; Niacinamide; PPAR gamma; Resveratrol; RNA, Small Interfering; Sirtuins; Stilbenes; Sus scrofa; Time Factors; Up-Regulation | 2009 |
Shear stress preconditioning modulates endothelial susceptibility to circulating TNF-alpha and monocytic cell recruitment in a simplified model of arterial bifurcations.
Topics: Anti-Inflammatory Agents; Atherosclerosis; Cell Adhesion; Cell Culture Techniques; Cells, Cultured; Computer Simulation; E-Selectin; Endothelial Cells; Fluorescent Antibody Technique; Humans; Models, Cardiovascular; Monocytes; NF-kappa B; Numerical Analysis, Computer-Assisted; Resveratrol; Simvastatin; Stilbenes; Stress, Mechanical; Stress, Physiological; Time Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2009 |
Synthesis, structural characterisation and biological evaluation of fluorinated analogues of resveratrol.
Topics: Antibiotics, Antineoplastic; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Epirubicin; Halogenation; Humans; Molecular Structure; Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2009 |
Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Caspase 3; Cell Survival; Dose-Response Relationship, Drug; Micelles; Nanoparticles; Oxidative Stress; PC12 Cells; Polymers; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
[Reversal effect of resveratrol on chemotherapy resistance in KBv200 cell line and underlying mechanisms].
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Paclitaxel; Resveratrol; Stilbenes; Vincristine | 2009 |
Antioxidant and anti-inflammatory properties of tomato fruits synthesizing different amounts of stilbenes.
Topics: Acyltransferases; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Fruit; Genes, Plant; Humans; Plants, Genetically Modified; Promoter Regions, Genetic; Resveratrol; Solanum lycopersicum; Stilbenes; U937 Cells; Vitis | 2009 |
Structure-activity relationships of resveratrol and derivatives in breast cancer cells.
Topics: Binding Sites; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Humans; Models, Molecular; Resveratrol; Stilbenes; Structure-Activity Relationship | 2009 |
Is white wine as "heart healthy" as red wine?
Topics: Antioxidants; Cardiovascular Diseases; Flavonoids; Humans; Phenols; Polyphenols; Resveratrol; Stilbenes; Wine | 2009 |
Antioxidant oligostilbenoids from the stem wood of Hopea hainanensis.
Topics: Antioxidants; Dipterocarpaceae; Free Radical Scavengers; Molecular Structure; Plant Stems; Resveratrol; Stilbenes | 2009 |
Resveratrol and quercetin cooperate to induce senescence-like growth arrest in C6 rat glioma cells.
Topics: Aging; Animals; Animals, Newborn; Anticarcinogenic Agents; Antioxidants; Apoptosis; Astrocytes; Caspases; Colony-Forming Units Assay; Drug Combinations; Drug Synergism; Glioma; Humans; Immunoblotting; Mice; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2009 |
A miracle molecule? Research is finding that a substance called resveratrol may lower blood glucose--and even extend life.
Topics: Blood Glucose; Diet, Diabetic; Energy Intake; Humans; Hypoglycemic Agents; Resveratrol; Stilbenes; Vasodilator Agents; Wine | 2009 |
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Safety studies conducted on high-purity trans-resveratrol in experimental animals.
Topics: Animals; Antioxidants; Chromosome Aberrations; Embryo, Mammalian; Embryonic Development; Eye; Female; Humans; Local Lymph Node Assay; Male; Micronucleus Tests; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reproduction; Resveratrol; Salmonella typhimurium; Skin Irritancy Tests; Stilbenes; Toxicity Tests | 2009 |
Resveratrol ameliorates DNA damage, prooxidant and antioxidant imbalance in 1,2-dimethylhydrazine induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Antioxidants; Carcinogens; Colonic Neoplasms; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
The janus face of resveratrol in astroglial cells.
Topics: Actins; Analysis of Variance; Animals; Antioxidants; Astrocytes; Dose-Response Relationship, Drug; Drug Interactions; Electrophoretic Mobility Shift Assay; Glioma; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Hydrogen Peroxide; Nerve Growth Factors; NF-kappa B; Oxidants; Phorbol Esters; Propidium; Rats; Reactive Oxygen Species; Resveratrol; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stilbenes | 2009 |
Interaction of the chemopreventive agent resveratrol and its metabolite, piceatannol, with model membranes.
Topics: Calorimetry, Differential Scanning; Electron Spin Resonance Spectroscopy; Liposomes; Membranes, Artificial; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thermodynamics | 2009 |
Improvements of cellular stress response on resveratrol in liposomes.
Topics: Antioxidants; Biological Transport; Cell Line; Cell Shape; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Compounding; Electron Spin Resonance Spectroscopy; Humans; Liposomes; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Mitochondria; Oxidation-Reduction; Particle Size; Resveratrol; Stilbenes; Stress, Physiological; Time Factors; Ultraviolet Rays | 2009 |
Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.
Topics: Apoptosis Regulatory Proteins; Autophagy; Base Sequence; Beclin-1; Cell Line, Tumor; Consensus Sequence; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; MicroRNAs; Molecular Sequence Data; Neoplasms; Oligonucleotide Array Sequence Analysis; Resveratrol; Sirolimus; Stilbenes; Vacuoles | 2009 |
[Inhibitory effect of resveratrol on the growth of human colon cancer ls174t cells and its subcutaneously transplanted tumor in nude mice and the mechanism of action].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Messenger; Stilbenes; Tumor Burden | 2009 |
A concise synthesis of glucuronide metabolites of urolithin-B, resveratrol, and hydroxytyrosol.
Topics: Coumarins; Glucuronides; Glycosylation; Phenylethyl Alcohol; Resveratrol; Stereoisomerism; Stilbenes | 2009 |
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1.
Topics: Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Caloric Restriction; Coronary Vessels; Endothelial Cells; Inflammation; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Resveratrol alters proliferative responses and apoptosis in human activated B lymphocytes in vitro.
Topics: Adolescent; Adult; Antigens, CD19; Antineoplastic Agents, Phytogenic; Apoptosis; B-Lymphocytes; Caspase 3; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression; Genes, bcl-2; Humans; Immunoglobulin G; Immunoglobulin M; Kaempferols; Lymphocyte Activation; Male; Middle Aged; Plant Extracts; Pokeweed Mitogens; Quercetin; Resveratrol; Stilbenes; Young Adult | 2009 |
Anti-inflammatory action of pterostilbene is mediated through the p38 mitogen-activated protein kinase pathway in colon cancer cells.
Topics: Anti-Inflammatory Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cytokines; Humans; Inflammation; MAP Kinase Signaling System; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2009 |
A new insight into resveratrol as an atheroprotective compound: inhibition of lipid peroxidation and enhancement of cholesterol efflux.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cholesterol; Dose-Response Relationship, Drug; Free Radical Scavengers; Humans; Kinetics; Linear Models; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mice; Oxidation-Reduction; Resveratrol; Stilbenes | 2009 |
Effect of resveratrol and zinc on intracellular zinc status in normal human prostate epithelial cells.
Topics: Adult; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Male; Prostate; Resveratrol; Stilbenes; Young Adult; Zinc | 2009 |
The effect of resveratrol in tracheal tissue of rats exposed to cigarette smoke.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Atmosphere Exposure Chambers; Epithelial Cells; Inhalation Exposure; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tobacco Smoke Pollution; Trachea | 2009 |
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.
Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid beta-Peptides; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Molecular Sequence Data; Oxidative Stress; Peptide Fragments; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
The inhibitory effect of resveratrol on leptin secretion from rat adipocytes.
Topics: Adipocytes; Animals; Cells, Cultured; Glucose; Lactic Acid; Leptin; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Resveratrol induces senescence-like growth inhibition of U-2 OS cells associated with the instability of telomeric DNA and upregulation of BRCA1.
Topics: Antioxidants; Blotting, Southern; BRCA1 Protein; Cell Line, Tumor; Cellular Senescence; DNA; Gene Expression Regulation, Neoplastic; Humans; In Situ Hybridization, Fluorescence; Models, Biological; Resveratrol; Serine; Sirtuin 1; Sirtuins; Stilbenes; Telomere; Up-Regulation | 2009 |
Antioxidant and lipoxygenase inhibitory activity of oligostilbenes from the leaf and stem of Vitis amurensis.
Topics: Antioxidants; Benzofurans; Flavanones; Lipid Peroxidation; Lipoxygenase; Lipoxygenase Inhibitors; Plant Extracts; Plant Leaves; Plant Stems; Resveratrol; Stilbenes; Vitis | 2009 |
The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunction in vitro: role of AMP-activated protein kinase.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Calcium-Binding Proteins; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; High-Temperature Requirement A Serine Peptidase 2; In Vitro Techniques; Male; MAP Kinase Signaling System; Mice; Mitochondrial Proteins; Myocardial Contraction; Myocytes, Cardiac; Protease Inhibitors; Pyrimidinones; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Serine Endopeptidases; Stilbenes; Streptozocin; Thiones; X-Linked Inhibitor of Apoptosis Protein | 2009 |
Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aorta; Atherosclerosis; Basigin; Cell Movement; Cells, Cultured; Cross-Linking Reagents; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-18; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Vasculitis | 2009 |
Resveratrol, a natural antioxidant, attenuates intestinal ischemia/reperfusion injury in rats.
Topics: Animals; Antioxidants; Bacterial Translocation; Female; Free Radical Scavengers; Intestinal Mucosa; Intestines; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Peroxidase; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase | 2009 |
Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Boronic Acids; Bortezomib; Caspase 10; Caspase 8; Cell Line, Tumor; Drug Synergism; fas Receptor; Fas-Associated Death Domain Protein; Flow Cytometry; Fluorescent Antibody Technique; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia, T-Cell; Membrane Microdomains; Microscopy, Confocal; Mitochondria; Multiple Myeloma; Phosphorylcholine; Pyrazines; Resveratrol; Signal Transduction; Stilbenes | 2009 |
In vitro effects of resveratrol on Trichinella spiralis.
Topics: Animals; Anthelmintics; Larva; Rats; Rats, Wistar; Resveratrol; Stilbenes; Survival Analysis; Trichinella spiralis | 2009 |
Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: implications for a mechanism of lifespan prolongation and cancer protection.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Resveratrol; S Phase; Signal Transduction; Stilbenes | 2009 |
Interaction of dietary resveratrol with animal-associated bacteria.
Topics: Animals; Bacteria; Biotransformation; Humans; Resveratrol; Stilbenes | 2009 |
Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats.
Topics: Animals; Apoptosis; Cardiotonic Agents; Heart; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Glioma; Humans; Membrane Potentials; Microscopy, Fluorescence; Mitochondrial Membranes; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2009 |
Resveratrol exhibits a strong cytotoxic activity in cultured cells and has an antiviral action against polyomavirus: potential clinical use.
Topics: Animals; Anticarcinogenic Agents; Antiviral Agents; Cell Proliferation; Cells, Cultured; DNA, Viral; Fibroblasts; HL-60 Cells; Humans; Mice; Polyomavirus; Polyomavirus Infections; Resveratrol; Stilbenes; Tumor Virus Infections; Virus Replication | 2009 |
Resveratrol protects spatial learning in middle-aged C57BL/6 mice from effects of ethanol.
Topics: Aging; Animals; Antioxidants; Ethanol; Female; Learning; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Resveratrol; Space Perception; Spatial Behavior; Stilbenes | 2009 |
Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study.
Topics: Amyloid; Humans; Islet Amyloid Polypeptide; Membrane Lipids; Microscopy, Atomic Force; Models, Biological; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Rays | 2009 |
Antioxidative effect of some hydroxy substituted aromatic bisimines.
Topics: Antioxidants; Biphenyl Compounds; Chloroform; Free Radicals; Imines; Methanol; Picrates; Resveratrol; Stilbenes | 2009 |
Is resveratrol the magic bullet for pulmonary hypertension?
Topics: Animals; Blood Pressure; Cell Proliferation; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Models, Biological; Monocrotaline; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pulmonary Artery; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factors; Vasodilation; Vasodilator Agents | 2009 |
Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Blood Pressure; Blotting, Western; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Interleukin-6; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Tumor Necrosis Factors; Vasodilation; Vasodilator Agents | 2009 |
Effects of resveratrol analogs on steroidogenesis and mitochondrial function in rat Leydig cells in vitro.
Topics: Androstenedione; Animals; Cells, Cultured; Chorionic Gonadotropin; Drug Evaluation, Preclinical; Enzyme Inhibitors; Leydig Cells; Male; Membrane Potential, Mitochondrial; Mitochondria; Phosphoproteins; Progesterone; Rats; Rats, Sprague-Dawley; Resveratrol; Steroid 17-alpha-Hydroxylase; Steroids; Stilbenes; Structure-Activity Relationship; Tetrazolium Salts | 2009 |
Resveratrol protects against ultraviolet A-mediated inhibition of the phagocytic function of human retinal pigment epithelial cells via large-conductance calcium-activated potassium channels.
Topics: Cell Line; Enzyme Inhibitors; Humans; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Meclofenamic Acid; Phagocytosis; Resveratrol; Stilbenes; Ultraviolet Rays | 2009 |
Spontaneous and 5-fluorouracil-induced centrosome amplification lowers the threshold to resveratrol-evoked apoptosis in colon cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 6; Centrosome; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Activation; Fluorouracil; HCT116 Cells; Humans; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation | 2010 |
Resveratrol protects mitochondria against oxidative stress through AMP-activated protein kinase-mediated glycogen synthase kinase-3beta inhibition downstream of poly(ADP-ribose)polymerase-LKB1 pathway.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Cell Line; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mitochondria; Oxidative Stress; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
Unraveling the relationship between grapes and health.
Topics: Drug Synergism; Fruit; Health Promotion; Humans; Phytotherapy; Plant Preparations; Resveratrol; Stilbenes; Vitis | 2009 |
Identification and bioactivities of resveratrol oligomers and flavonoids from Carex folliculata seeds.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Carex Plant; Cell Line, Tumor; Cell Proliferation; Flavonoids; Humans; Methicillin-Resistant Staphylococcus aureus; Neoplasms; Plant Extracts; Resveratrol; Seeds; Stilbenes | 2009 |
5-MCA-NAT does not act through NQO2 to reduce intraocular pressure in New-Zealand white rabbit.
Topics: Amino Acid Sequence; Animals; Base Sequence; Chloroquine; Ciliary Body; Cornea; Humans; Immunohistochemistry; Intraocular Pressure; Molecular Sequence Data; Quinone Reductases; Rabbits; Receptors, Melatonin; Resveratrol; RNA Interference; RNA, Small Interfering; Sequence Alignment; Stilbenes; Tryptamines; Vitamin K 3 | 2009 |
Plasma membrane and nuclear envelope integrity during the blebbing stage of apoptosis: a time-lapse study.
Topics: Antineoplastic Agents; Apoptosis; Butyrates; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleolus; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Nuclear Envelope; Phosphatidylserines; Resveratrol; Stilbenes; Time Factors | 2009 |
Implication of signaling pathways involving calcium, phosphorylation and active oxygen species in methyl jasmonate-induced defense responses in grapevine cell cultures.
Topics: Acetates; Calcium; Cantharidin; Cells, Cultured; Cyclopentanes; Dicarboxylic Acids; Enzyme Inhibitors; Glucosides; NADPH Oxidases; Oxylipins; Phosphoric Monoester Hydrolases; Phosphorylation; Plant Growth Regulators; Plant Proteins; Reactive Oxygen Species; Resveratrol; RNA, Plant; Signal Transduction; Stilbenes; Superoxide Dismutase; Vitis | 2009 |
Tyrosinase inhibitor activity of coumarin-resveratrol hybrids.
Topics: Coumarins; Enzyme Inhibitors; Inhibitory Concentration 50; Monophenol Monooxygenase; Resveratrol; Stilbenes; Structure-Activity Relationship | 2009 |
Simultaneous determination of oxyresveratrol and resveratrol in rat bile and urine by HPLC after oral administration of Smilax china extract.
Topics: Administration, Oral; Animals; Bile; Chromatography, High Pressure Liquid; Female; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Sensitivity and Specificity; Smilax; Stilbenes | 2009 |
Coordinated posttranscriptional mRNA population dynamics during T-cell activation.
Topics: Antigens, Surface; ELAV Proteins; ELAV-Like Protein 1; Gene Expression Regulation; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Oligonucleotide Array Sequence Analysis; Poly(A)-Binding Proteins; Resveratrol; Ribonucleoproteins; RNA-Binding Proteins; RNA, Messenger; Stilbenes; T-Lymphocytes | 2009 |
Rapid separation of three glucosylated resveratrol analogues from the invasive plant Polygonum cuspidatum by high-speed countercurrent chromatography.
Topics: Countercurrent Distribution; Fallopia japonica; Glucosides; Molecular Structure; Plant Extracts; Resveratrol; Solvents; Stilbenes | 2009 |
[Suppressive effect of resveratrol on growth of U251 human glioma cells and its correlated mechanism].
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Caspase 3; Cell Line, Tumor; Cyclin D1; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Proto-Oncogene Proteins c-bcl-2; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2009 |
Resveratrol induces mitochondrial alterations, autophagy and a cryptobiosis-like state in scuticociliates.
Topics: Animals; Antiprotozoal Agents; Autophagy; Culture Media; Microbial Viability; Mitochondria; Oligohymenophorea; Plants; Resveratrol; Stilbenes | 2009 |
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.
Topics: Acetylation; Animals; Base Sequence; Binding Sites; Cell Line; Cytosol; DNA; Enzyme Activation; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 4; Humans; Molecular Sequence Data; Niacinamide; Phosphoenolpyruvate Carboxykinase (GTP); Promoter Regions, Genetic; Resveratrol; Sirtuins; Stilbenes; Transcription Factor AP-1; Transcription, Genetic | 2009 |
Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level. Functional and modelling studies.
Topics: Animals; Antioxidants; Arachidonic Acid; Aspirin; Blood Platelets; Cyclooxygenase 1; Drug Interactions; Gallic Acid; Humans; In Vitro Techniques; Male; Membrane Proteins; Mice; Models, Biological; Models, Molecular; Platelet Aggregation; Platelet Aggregation Inhibitors; Quercetin; Reactive Oxygen Species; Resveratrol; Stilbenes; Thermodynamics | 2009 |
Resveratrol-loaded calcium-pectinate beads: effects of formulation parameters on drug release and bead characteristics.
Topics: Antioxidants; Calcium Chloride; Chemistry, Pharmaceutical; Cross-Linking Reagents; Drug Stability; Excipients; Freeze Drying; Humidity; Hydrogen-Ion Concentration; Kinetics; Microscopy, Electron, Scanning; Particle Size; Pectins; Polygalacturonase; Resveratrol; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes; Surface-Active Agents | 2010 |
Resveratrol promotes osteogenic differentiation and protects against dexamethasone damage in murine induced pluripotent stem cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Differentiation; Cell Line; Cell Survival; Cell Transplantation; Cells, Cultured; Dexamethasone; Embryonic Stem Cells; Glucocorticoids; Green Fluorescent Proteins; Induced Pluripotent Stem Cells; Lentivirus; Mice; Mice, Nude; Multipotent Stem Cells; Octamer Transcription Factor-3; Osteocytes; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Transduction, Genetic | 2010 |
Grapevine cell early activation of specific responses to DIMEB, a resveratrol elicitor.
Topics: beta-Cyclodextrins; Cell Division; Cell Wall; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Oligonucleotide Array Sequence Analysis; Resveratrol; RNA, Plant; Stilbenes; Vitis | 2009 |
Antiproliferative effects of resveratrol and the mediating role of resveratrol targeting protein NQO2 in androgen receptor-positive, hormone-non-responsive CWR22Rv1 cells.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Male; Prostatic Neoplasms; Quinone Reductases; Receptors, Androgen; Resveratrol; RNA, Small Interfering; Stilbenes | 2009 |
Scutellarin sensitizes drug-evoked colon cancer cell apoptosis through enhanced caspase-6 activation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apigenin; Apoptosis; Blotting, Western; Caspase 6; Colonic Neoplasms; Drug Therapy, Combination; Enzyme Activation; Fluorouracil; Glucuronates; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2009 |
Potent antioxidative activity of Vineatrol30 grapevine-shoot extract.
Topics: Animals; Cell Line; Cricetinae; Free Radical Scavengers; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Lipid Peroxidation; Phenols; Plant Shoots; Promoter Regions, Genetic; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Transcriptional Activation; Vitis | 2009 |
Effect of ultraviolet doses in combined ultraviolet-ultrasound treatments on trans-resveratrol and trans-piceid contents in sliced peanut kernels.
Topics: Arachis; Chromatography, High Pressure Liquid; Dose-Response Relationship, Radiation; Drugs, Chinese Herbal; Glucosides; Resveratrol; Seeds; Stilbenes; Ultrasonics; Ultraviolet Rays | 2009 |
Resveratrol inhibited Tat-induced HIV-1 LTR transactivation via NAD(+)-dependent SIRT1 activity.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; HeLa Cells; HIV Long Terminal Repeat; HIV-1; Humans; NAD; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Sirtuins; Stilbenes; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Virus Replication | 2009 |
RETRACTED: Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells.
Topics: Angiogenesis Inhibitors; Animals; Ascorbic Acid; Base Sequence; Cell Differentiation; Cell Line; Core Binding Factor Alpha 1 Subunit; Culture Media; Genes, Reporter; Mice; Molecular Sequence Data; Multipotent Stem Cells; Osteoblasts; Promoter Regions, Genetic; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes; Transfection; Wnt Proteins; Wnt3 Protein; Wnt3A Protein | 2009 |
Resveratrol prevents hyperglycemia-induced endothelial dysfunction via activation of adenosine monophosphate-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cytoprotection; Endothelium, Vascular; Enzyme Activation; Humans; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Resveratrol; Stilbenes; Superoxides; Vasodilation | 2009 |
Reversal of doxorubicin-induced vascular dysfunction by resveratrol in rat thoracic aorta: Is there a possible role of nitric oxide synthase inhibition?
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Antioxidants; Aorta, Thoracic; Doxorubicin; Drug Antagonism; Endothelium, Vascular; Immunohistochemistry; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prospective Studies; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
Genistein and resveratrol, alone and in combination, suppress prostate cancer in SV-40 tag rats.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antigens, Polyomavirus Transforming; Apoptosis; Cell Growth Processes; Genistein; Histone Acetyltransferases; Immunohistochemistry; Insulin-Like Growth Factor I; Ki-67 Antigen; Male; Nuclear Receptor Coactivator 3; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Resveratrol; Stilbenes; Trans-Activators | 2009 |
The resveratrol analogue 4,4'-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol.
Topics: Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Chromatin Assembly and Disassembly; DNA Polymerase III; Fibroblasts; Humans; Lung; Oligonucleotide Array Sequence Analysis; Protein Conformation; Resveratrol; Stilbenes; Vitis; Wine | 2009 |
A fluorometric assay of SIRT1 deacetylation activity through quantification of nicotinamide adenine dinucleotide.
Topics: Catechin; Coumarins; Fluorescent Dyes; NAD; Peptides; Resveratrol; Sirtuin 1; Spectrometry, Fluorescence; Stilbenes | 2009 |
Altered Ca2+ homeostasis in the skeletal muscle of DJ-1 null mice.
Topics: Animals; Antioxidants; Calcium; Gene Expression Regulation; Homeostasis; Membrane Potentials; Mice; Mice, Knockout; Muscle Cells; Muscle Fibers, Skeletal; Muscle, Skeletal; Oncogene Proteins; Peroxiredoxins; Protein Deglycase DJ-1; Resveratrol; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stilbenes | 2011 |
Combination treatment with resveratrol and sulforaphane induces apoptosis in human U251 glioma cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glioma; Humans; Isothiocyanates; Resveratrol; Stilbenes; Sulfoxides; Thiocyanates | 2010 |
[Effects of resveratrol on nuclear factor-kappaB and pro-inflammatory factors from lipopolysaccharide activated murine peritoneal macrophages].
Topics: Animals; Female; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2009 |
UCF-101 mitigates streptozotocin-induced cardiomyocyte dysfunction: role of AMPK.
Topics: Adenylate Kinase; Animals; Antioxidants; Blood Glucose; Blotting, Western; Caspase 3; Cell Separation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation; Protease Inhibitors; Protein Phosphatase 2; Pyrimidinones; Resveratrol; Stilbenes; Thiones | 2009 |
The genotoxicity study of resveratrol in primary gastric adenocarcinoma cell cultures.
Topics: Aged; Humans; Male; Micronucleus Tests; Mutagenicity Tests; Resveratrol; Stilbenes; Stomach Neoplasms; Tumor Cells, Cultured | 2009 |
The effects of resveratrol on cyclooxygenase-1 and cyclooxygenase-2 mRNA and protein levels in diabetic rat kidneys.
Topics: Animals; Body Weight; Cyclooxygenase 1; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Kidney; Male; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Software; Stilbenes | 2010 |
Resveratrol opposite effects on rat tissue lipoperoxidation: pro-oxidant during day-time and antioxidant at night.
Topics: Animals; Antioxidants; Circadian Rhythm; Heart; Kidney; Light; Lipid Peroxidation; Liver; Male; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2009 |
Protective effect of resveratrol in severe acute pancreatitis-induced brain injury.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Brain; Brain Injuries; Caspase 3; Cytochromes c; Enzyme-Linked Immunosorbent Assay; Male; Membrane Proteins; Microscopy, Electron; Myelin Basic Protein; Neuroprotective Agents; Pancreas; Pancreatitis, Acute Necrotizing; Phosphoproteins; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Time Factors; Vasodilator Agents; Zonula Occludens-1 Protein | 2009 |
Phenolic content of grapevine leaves (Vitis labrusca var. Bordo) and its neuroprotective effect against peroxide damage.
Topics: Animals; Antioxidants; Cerebellum; Cerebral Cortex; Hippocampus; Neuroprotective Agents; Oxidative Stress; Peroxides; Phenols; Plant Leaves; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Vitis | 2010 |
Resveratrol and its antifungal activity against Candida species.
Topics: Antifungal Agents; Candida; Candidiasis; Humans; Microbial Sensitivity Tests; Resveratrol; Stilbenes | 2011 |
Resveratrol protects against irradiation-induced hepatic and ileal damage via its anti-oxidative activity.
Topics: Animals; Antioxidants; Apoptosis; Glutathione; Ileal Diseases; Ileum; Lipid Peroxidation; Liver; Liver Diseases; Liver Function Tests; Male; Peroxidase; Radiation Injuries, Experimental; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2009 |
E-Combretastatin and E-resveratrol structural modifications: antimicrobial and cancer cell growth inhibitory beta-E-nitrostyrenes.
Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bibenzyls; Cell Line, Tumor; Cell Proliferation; Fungi; Humans; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship; Styrenes; Tubulin; Tubulin Modulators | 2009 |
SIRT1 regulation of apoptosis of human chondrocytes.
Topics: Adult; Apoptosis; bcl-2-Associated X Protein; Benzamides; Case-Control Studies; Caspase 3; Caspase 9; Cells, Cultured; Chondrocytes; Enzyme Inhibitors; Humans; Male; Naphthols; Niacinamide; Nitric Oxide; Osteoarthritis, Knee; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sirtuins; Stilbenes | 2009 |
Changes of resveratrol and antioxidant enzymes during UV-induced plant defense response in peanut seedlings.
Topics: Antioxidants; Arachis; Catalase; Gene Expression Regulation; Glutathione Reductase; Hydrogen Peroxide; Malondialdehyde; Resveratrol; Seedlings; Stilbenes; Superoxide Dismutase; Ultraviolet Rays | 2010 |
Antineoplastic agents. 579. Synthesis and cancer cell growth evaluation of E-stilstatin 3: a resveratrol structural modification.
Topics: Antineoplastic Agents; Bibenzyls; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Molecular Conformation; Molecular Structure; Prodrugs; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2009 |
Differential regulation of the hydrogen-peroxide-induced inhibition of gap-junction intercellular communication by resveratrol and butylated hydroxyanisole.
Topics: Animals; Antioxidants; Butylated Hydroxyanisole; Cell Communication; Cell Line; Connexin 43; Free Radicals; Gap Junctions; Hydrogen Peroxide; Phosphorylation; Rats; Rats, Inbred F344; Resveratrol; Signal Transduction; Stilbenes | 2009 |
SIRT1 regulates Tat-induced HIV-1 transactivation through activating AMP-activated protein kinase.
Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Gene Expression Regulation, Viral; Gene Knockdown Techniques; HIV-1; Host-Pathogen Interactions; Humans; NAD; Niacinamide; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation | 2009 |
Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro.
Topics: Catechin; Cell Line; Endothelial Cells; Gene Expression; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phenols; Quercetin; Resveratrol; Stilbenes | 2009 |
Monitoring of long-term effects of resveratrol on cell cycle progression of human HeLa cells after administration of a single dose.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinases; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; HeLa Cells; Humans; Protein Kinase Inhibitors; Purines; Resveratrol; Ribonucleotide Reductases; Roscovitine; Stilbenes; Time Factors | 2009 |
Gallic acid induces neuronal cell death through activation of c-Jun N-terminal kinase and downregulation of Bcl-2.
Topics: Animals; Anthracenes; Antioxidants; Apoptosis; Blotting, Western; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Gallic Acid; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Molecular Structure; Neurons; Oxidants; PC12 Cells; Phosphorylation; Plasmids; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Rats; Resveratrol; Stilbenes; Transfection | 2009 |
Ectonucleotidase and acetylcholinesterase activities in synaptosomes from the cerebral cortex of streptozotocin-induced diabetic rats and treated with resveratrol.
Topics: 5'-Nucleotidase; Acetylcholinesterase; Adenosine Triphosphatases; Animals; Blood Glucose; Body Weight; Cerebral Cortex; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Male; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Synaptosomes | 2009 |
The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients.
Topics: Age Factors; Aging; Animals; Dietary Supplements; DNA, Mitochondrial; Energy Metabolism; Female; Humans; Infertility, Female; Mice; Mice, Inbred ICR; Mitochondria; Oocytes; Pregnancy; Resveratrol; Stilbenes; Thioctic Acid; Ubiquinone | 2010 |
Cellular factors involved in CXCL8 expression induced by glycated serum albumin in vascular smooth muscle cells.
Topics: Butadienes; Cells, Cultured; Curcumin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Interleukin-8; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; NF-kappa B; Nitriles; Onium Compounds; Promoter Regions, Genetic; Resveratrol; Serum Albumin; Stilbenes; Toll-Like Receptor 4; Transcriptional Activation; Up-Regulation | 2010 |
Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Growth Processes; Down-Regulation; Female; Humans; Insulin; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Ovarian Neoplasms; Peptide Elongation Factor 1; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2009 |
FoxO1 and HNF-4 are involved in regulation of hepatic glucokinase gene expression by resveratrol.
Topics: Animals; Cells, Cultured; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; Glucokinase; Hepatocyte Nuclear Factor 4; Hepatocytes; Liver; Male; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Astrocytoma; Cell Line, Tumor; Cell Proliferation; Free Radicals; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation.
Topics: Amyloid; Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Cell Proliferation; Circular Dichroism; Dose-Response Relationship, Drug; Humans; Mice; Microscopy, Electron, Transmission; Molecular Conformation; Molecular Structure; Neuroblastoma; Peptide Fragments; Protein Structure, Quaternary; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Tetrazolium Salts; Thiazoles | 2009 |
Expression of sulfotransferases and sulfatases in human breast cancer: impact on resveratrol metabolism.
Topics: Aged; Arylsulfatases; Arylsulfotransferase; Biomarkers, Tumor; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Fluorescent Antibody Technique, Indirect; Humans; Middle Aged; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steryl-Sulfatase; Stilbenes; Sulfotransferases | 2010 |
Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells.
Topics: Antioxidants; Biosensing Techniques; Cells, Cultured; Chromatography, High Pressure Liquid; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Glutathione; Humans; Hydrogen Peroxide; Hyperglycemia; Microscopy, Fluorescence; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Resveratrol; RNA Interference; Sirtuin 1; Sirtuins; Stilbenes; Superoxide Dismutase; Transfection | 2009 |
Resveratrol inhibits prostaglandin formation in IL-1beta-stimulated SK-N-SH neuronal cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Humans; Inflammation; Interleukin-1beta; Isoenzymes; Microglia; Neurons; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Resveratrol; Stilbenes | 2009 |
In vitro compaction of germinal vesicle chromatin is beneficial to survival of vitrified cat oocytes.
Topics: Animals; Cats; Cells, Cultured; Chromatin; Cryopreservation; Cryoprotective Agents; Embryo Culture Techniques; Female; Fertilization in Vitro; Oocytes; Resveratrol; Stilbenes | 2009 |
The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds.
Topics: Amyloid; Benzothiazoles; Biological Assay; Curcumin; Fluorescent Dyes; Quercetin; Reproducibility of Results; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thiazoles | 2009 |
Vitamin C and resveratrol supplementation to rat dams treated with di(2-ethylhexyl)phthalate: impact on reproductive and oxidative stress end points in male offspring.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Catalase; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Gestational Age; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reproduction; Resveratrol; Stilbenes; Testis | 2009 |
Chunganenol: an unusual antioxidative resveratrol hexamer from Vitis chunganensis.
Topics: Antioxidants; Methanol; Molecular Structure; Plant Preparations; Plant Structures; Resveratrol; Stilbenes; Vitis | 2009 |
Phytochemical profiles of different mulberry (Morus sp.) species from China.
Topics: 1-Deoxynojirimycin; Anthocyanins; Beverages; China; Chromatography, High Pressure Liquid; Flavonoids; Fruit; Glucosides; Morus; Plant Leaves; Resveratrol; Rutin; Species Specificity; Stilbenes | 2009 |
Resveratrol.
Topics: Animals; Cardiotonic Agents; Dietary Supplements; Humans; Resveratrol; Stilbenes | 2009 |
Chemoprevention of ovarian cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Carcinoma; Chemoprevention; Chickens; Disease Models, Animal; Drug Delivery Systems; Fatty Acids, Omega-3; Female; Humans; Mice; Neoplasm Proteins; Ovarian Neoplasms; Phytoestrogens; Progestins; Resveratrol; Retinoids; Stilbenes; Vitamin D | 2009 |
Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells.
Topics: Animals; Cell Line; Epithelial Cells; Glucose; Kidney Glomerulus; Mice; Phosphorylation; Protein Biosynthesis; Proteins; Resveratrol; Stilbenes | 2010 |
CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells.
Topics: Caco-2 Cells; Calcitriol; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Diet; Dipeptidyl Peptidase 4; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Intestinal Mucosa; Intestines; Polychlorinated Dibenzodioxins; Quercetin; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes | 2009 |
Antioxidants change platelet responses to various stimulating events.
Topics: Antioxidants; Blood Platelets; Cell Adhesion; Cells, Cultured; Chromans; Collagen; Cyclooxygenase 1; Hemostasis; Humans; Malondialdehyde; Platelet Aggregation; Resveratrol; Stilbenes; Thromboxane B2 | 2009 |
Uptake of resveratrol and role of resveratrol-targeting protein, quinone reductase 2, in normally cultured human prostate cells.
Topics: Cell Cycle; Cells, Cultured; Humans; Male; NAD(P)H Dehydrogenase (Quinone); Prostate; Quinone Reductases; Resveratrol; Stilbenes | 2009 |
Leaf-associated bacteria from transgenic white poplar producing resveratrol-like compounds: isolation, molecular characterization, and evaluation of oxidative stress tolerance.
Topics: Bacteria; Bacterial Physiological Phenomena; Molecular Sequence Data; Oxidative Stress; Plant Leaves; Plants, Genetically Modified; Populus; Resveratrol; Stilbenes; Ultraviolet Rays | 2009 |
Effect of H/D isotopomerization in the assay of resveratrol by tandem mass spectrometry and isotope dilution method.
Topics: Deuterium; Humans; Isomerism; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Wine | 2009 |
Protective effects of resveratrol on small intestines against intestinal ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Catalase; Disease Models, Animal; Intestine, Small; L-Lactate Dehydrogenase; Liver; Male; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2009 |
Study on liver targeting effect of vinegar-baked Radix Bupleuri on resveratrol in mice.
Topics: Acetic Acid; Animals; Antioxidants; Chromatography, High Pressure Liquid; Drug Delivery Systems; Liver; Male; Medicine, Chinese Traditional; Mice; Resveratrol; Stilbenes; Tissue Distribution | 2009 |
Can resveratrol extend your life?
Topics: Clinical Trials as Topic; Humans; Life Expectancy; Resveratrol; Stilbenes | 2009 |
Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation.
Topics: Antioxidants; Apoptosis; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Lymphocyte Activation; Methionine Sulfoxide Reductases; Middle Aged; Oxidation-Reduction; Oxidative Stress; Oxygen; Proteasome Endopeptidase Complex; Reference Values; Resveratrol; Stilbenes; T-Lymphocytes | 2010 |
Evaluation of anti-leukemia effect of resveratrol by modulating STAT3 signaling.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Proliferation; Gene Expression Regulation, Leukemic; Humans; Jurkat Cells; Leukemia, T-Cell; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2010 |
Pharmacokinetics of trans-resveratrol following repeated administration in healthy elderly and young subjects.
Topics: Adult; Aged; Aging; Antiparkinson Agents; Drug Administration Schedule; Female; Humans; Levodopa; Male; Resveratrol; Stilbenes; Young Adult | 2009 |
Co-ordinated autophagy with resveratrol and γ-tocotrienol confers synergetic cardioprotection.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cardiotonic Agents; Chromans; Drug Synergism; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Signal Transduction; Stilbenes; Vitamin E | 2010 |
Antioxidative activity of the olive oil constituent hydroxy-1-aryl-isochromans in cells and cell-free systems.
Topics: Animals; Antioxidants; Cell-Free System; Cells, Cultured; Drug Evaluation, Preclinical; Flavonoids; Mitochondria; Models, Biological; Olive Oil; Oxidative Stress; PC12 Cells; Phenols; Plant Oils; Polyphenols; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Xanthine Oxidase | 2009 |
Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coumestrol; Estradiol; Estrogen Receptor alpha; Female; Genistein; Humans; Isoflavones; Phytoestrogens; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2010 |
Resveratrol supplementation gender independently improves endothelial reactivity and suppresses superoxide production in healthy rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antioxidants; Endothelium, Vascular; Female; Male; NAD; NADP; Nitric Oxide; Phenylephrine; Rats; Resveratrol; Sex Factors; Stilbenes; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Wine | 2009 |
Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex.
Topics: Acetylation; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Chromatin Immunoprecipitation; Cyclin-Dependent Kinase Inhibitor p21; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Immunoprecipitation; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Nucleosomes; Promoter Regions, Genetic; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Stilbenes; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2010 |
The red wine polyphenol resveratrol reduces polycyclic aromatic hydrocarbon-induced DNA damage in MCF-10A cells.
Topics: Anticarcinogenic Agents; Benz(a)Anthracenes; Cell Line, Tumor; Cytochrome P-450 Enzyme System; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Oxidation-Reduction; Resveratrol; Stilbenes; Wine | 2009 |
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma.
Topics: Animals; Behavior, Animal; Blotting, Western; Carcinoma, Hepatocellular; Cardiotoxins; Chemoprevention; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Feeding Behavior; Female; Heart; Hepatocytes; Humans; Liver; Liver Neoplasms; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Systole | 2011 |
Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype.
Topics: Adenylate Kinase; Cells, Cultured; Endothelial Cells; Gene Expression Regulation; Humans; Kruppel-Like Transcription Factors; MADS Domain Proteins; MAP Kinase Kinase 5; MEF2 Transcription Factors; Mitogen-Activated Protein Kinase 7; Myogenic Regulatory Factors; Nitric Oxide Synthase Type III; Phenotype; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Repressive effects of resveratrol on androgen receptor transcriptional activity.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA, Complementary; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Male; Prostatic Neoplasms; Receptors, Androgen; Resveratrol; Stilbenes; Transcription, Genetic; Transcriptional Activation | 2009 |
Central administration of resveratrol improves diet-induced diabetes.
Topics: Animals; Antioxidants; Blotting, Western; Body Weight; Brain; Diabetes Mellitus, Type 2; Dietary Fats; Eating; Glucose; Homeostasis; Hyperglycemia; Liver; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Protein Serine-Threonine Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes | 2009 |
Effect of resveratrol on tubular damage and interstitial fibrosis in kidneys of rats exposed to cigarette smoke.
Topics: Animals; Antioxidants; Fibrosis; Injections, Intraperitoneal; Kidney; Kidney Tubules; Male; Photomicrography; Rats; Rats, Wistar; Resveratrol; Smoking; Stilbenes | 2009 |
Resveratrol downregulates PI3K/Akt/mTOR signaling pathways in human U251 glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Caspase 3; Cell Line, Tumor; Cyclin D1; Dose-Response Relationship, Drug; Down-Regulation; Glioma; Humans; Phosphoinositide-3 Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2009 |
[Resveratrol increases sensitivity of CNE2 cells to chemotherapeutic drugs under hypoxia].
Topics: Antineoplastic Agents, Phytogenic; Carcinoma; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Multidrug Resistance-Associated Proteins; Nasopharyngeal Neoplasms; Paclitaxel; Resveratrol; Stilbenes | 2009 |
The evidence for solid lipid nanoparticles mediated cell uptake of resveratrol.
Topics: Anticarcinogenic Agents; Biological Availability; Cell Cycle; Cell Line, Transformed; Cell Nucleus; Cell Proliferation; Cell Shape; Cell Size; Delayed-Action Preparations; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Space; Keratinocytes; Lecithins; Lipids; Metabolism; Microscopy, Fluorescence; Nanoparticles; Necrosis; Particle Size; Poloxamer; Resveratrol; Static Electricity; Stilbenes | 2010 |
Colon-specific delivery of resveratrol: optimization of multi-particulate calcium-pectinate carrier.
Topics: Calcium Chloride; Chemistry, Pharmaceutical; Colon; Cross-Linking Reagents; Drug Carriers; Drug Compounding; Drug Stability; Gastric Juice; Hardness; Hydrogen-Ion Concentration; Intestinal Secretions; Kinetics; Particle Size; Pectins; Polyethyleneimine; Resveratrol; Solubility; Stilbenes; Surface Properties; Technology, Pharmaceutical | 2010 |
Curcumin synergizes with resveratrol to inhibit colon cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Body Weight; Cell Cycle; Cell Nucleus; Cell Proliferation; Cell Survival; Colonic Neoplasms; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Female; HCT116 Cells; Humans; Mice; Mice, SCID; NF-kappa B; Nuclear Proteins; Phosphorylation; Receptors, Growth Factor; Resveratrol; Software; Stilbenes; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2009 |
Resveratrol is not a direct activator of SIRT1 enzyme activity.
Topics: Acetylation; Cell Line; Heat-Shock Proteins; Humans; Peptides; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Recombinant Fusion Proteins; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Transcription Factors | 2009 |
Apoptosis induced by capsaicin and resveratrol in colon carcinoma cells requires nitric oxide production and caspase activation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Arginine; Capsaicin; Caspase 3; Caspase 9; Colonic Neoplasms; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; HCT116 Cells; Humans; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nucleosomes; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2009 |
dSir2 and Dmp53 interact to mediate aspects of CR-dependent lifespan extension in D. melanogaster.
Topics: Age Factors; Animals; Animals, Genetically Modified; Biocatalysis; Caloric Restriction; DNA; Drosophila melanogaster; Drosophila Proteins; Female; Gene Expression; Histone Deacetylases; Immunoprecipitation; Kinetics; Longevity; Mifepristone; Peptide Fragments; Protein Binding; Protein Interaction Mapping; Recombinant Proteins; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Survival Analysis; Transfection; Tumor Suppressor Protein p53 | 2009 |
Antioxidant and antigenotoxic activities of purple grape juice--organic and conventional--in adult rats.
Topics: Animals; Antimutagenic Agents; Antioxidants; Beverages; Brain; Carbon Tetrachloride; Catalase; Catechin; Chemical and Drug Induced Liver Injury; DNA Damage; Food, Organic; Fruit; Lipid Peroxidation; Liver; Phenols; Phytotherapy; Plant Preparations; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vitis | 2009 |
Oral administration of resveratrol in suppression of pulmonary metastasis of BALB/c mice challenged with CT26 colorectal adenocarcinoma cells.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Immunologic Factors; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Neoplasm Transplantation; Random Allocation; Resveratrol; Stilbenes; Survival Analysis; Tumor Burden | 2010 |
Multivariant optimization, validation, and application of capillary electrophoresis for simultaneous determination of polyphenols and phenolic acids in Brazilian wines.
Topics: Brazil; Electrophoresis, Capillary; Flavonoids; Hydroxybenzoates; Limit of Detection; Phenols; Polyphenols; Reproducibility of Results; Resveratrol; Stilbenes; Wine | 2009 |
Differential effect of resveratrol on nitric oxide production in endothelial f-2 cells.
Topics: Animals; Blotting, Western; Endothelium, Vascular; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Receptors, Vascular Endothelial Growth Factor; Resveratrol; Stilbenes | 2009 |
Effect of resveratrol on Helicobacter pylori-induced interleukin-8 secretion, reactive oxygen species generation and morphological changes in human gastric epithelial cells.
Topics: Antioxidants; Cell Adhesion; Cell Line; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Gastric Mucosa; Helicobacter pylori; Humans; Interleukin-8; Reactive Oxygen Species; Resveratrol; Stilbenes | 2009 |
In vitro evidence for the formation of reactive intermediates of resveratrol in human liver microsomes.
Topics: Antioxidants; Catalase; Chromatography, High Pressure Liquid; Epoxide Hydrolases; Free Radical Scavengers; Glutathione; Humans; Indolequinones; Metabolic Networks and Pathways; Microsomes, Liver; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Superoxide Dismutase | 2010 |
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states.
Topics: Acetylation; Animals; Dimerization; Disease Models, Animal; Down-Regulation; Hep G2 Cells; Histone Deacetylases; Liver; Liver Diseases; Male; Mice; Mutagenesis, Site-Directed; p300-CBP Transcription Factors; Protein Stability; Receptors, Cytoplasmic and Nuclear; Resveratrol; Retinoid X Receptor alpha; RNA, Small Interfering; Sirtuin 1; Stilbenes; Transcription Factors; Transcriptional Activation | 2009 |
A novel resveratrol analogue HS-1793 treatment overcomes the resistance conferred by Bcl-2 and is associated with the formation of mature PML nuclear bodies in renal clear cell carcinoma Caki-1 cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Humans; Intranuclear Inclusion Bodies; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Membrane Potential, Mitochondrial; Microscopy, Confocal; Naphthols; Nuclear Proteins; Promyelocytic Leukemia Protein; Proto-Oncogene Proteins c-bcl-2; Resorcinols; Resveratrol; Stilbenes; Transcription Factors; Tumor Suppressor Proteins | 2009 |
Phosphoinositide 3-kinase is a novel target of piceatannol for inhibiting PDGF-BB-induced proliferation and migration in human aortic smooth muscle cells.
Topics: Adenosine Triphosphate; Angiogenesis Inducing Agents; Aorta; Becaplermin; Binding, Competitive; Cell Division; Cell Movement; Cells, Cultured; Drug Interactions; Enzyme Inhibitors; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Stilbenes; Syk Kinase | 2010 |
Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1beta-induced NF-kappaB-mediated inflammation and apoptosis.
Topics: Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Chondrocytes; Curcumin; Drug Synergism; Humans; Inflammation; Interleukin-1beta; Microscopy, Electron, Transmission; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes | 2009 |
Protective effect of resveratrol against lipopolysaccharide-induced oxidative stress in rat brain.
Topics: Animals; Antioxidants; Brain; Catalase; Endotoxemia; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Peroxidases; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2009 |
Resveratrol and ascorbic acid prevent DNA damage induced by cryopreservation in human semen.
Topics: Adult; Antioxidants; Ascorbic Acid; Cryopreservation; DNA Damage; Humans; In Vitro Techniques; Infertility, Male; Male; Resveratrol; Semen Preservation; Stilbenes | 2010 |
Short-step synthesis of a resveratrol derivative from commercially available 1,3-dimethoxybenzene and 4-vinylanisole.
Topics: Anisoles; Catalysis; Iridium; Resveratrol; Stereoisomerism; Stilbenes; Styrenes | 2009 |
Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Proliferation; Cyclooxygenase 2; Deoxycytidine; Gemcitabine; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2010 |
Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Intestinal Mucosa; Polyethylene Glycols; Prodrugs; Rats; Resveratrol; Stilbenes | 2009 |
Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1.
Topics: Acetylation; Animals; Binding Sites; Binding, Competitive; Catalysis; Chelating Agents; Edetic Acid; Humans; Kinetics; Mutation; NAD; Protein Binding; Resveratrol; Sirtuin 1; Spectrometry, Fluorescence; Stilbenes; Substrate Specificity; Zinc; Zinc Fingers | 2010 |
Which model based on fluorescence quenching is suitable to study the interaction between trans-resveratrol and BSA?
Topics: Animals; Antioxidants; Binding Sites; Cattle; Fluorescence; Mathematics; Models, Chemical; Models, Molecular; Protein Binding; Resveratrol; Serum Albumin, Bovine; Spectrometry, Fluorescence; Stilbenes | 2010 |
Antioxidant activities of curcumin and combinations of this curcuminoid with other phytochemicals.
Topics: Antioxidants; Curcumin; Drug Evaluation, Preclinical; Plant Extracts; Quercetin; Resveratrol; Stilbenes | 2010 |
Resveratrol modulates tumor cell proliferation and protein translation via SIRT1-dependent AMPK activation.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Female; Gene Expression; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Protein Biosynthesis; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2010 |
Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch by topical application of resveratrol complexed with 2-hydroxypropyl-beta-cyclodextrin.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; beta-Cyclodextrins; Carcinogens; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Cheek; Cricetinae; Drug Combinations; Mesocricetus; Mouth Neoplasms; Pharmaceutical Vehicles; Resveratrol; Stilbenes | 2010 |
Molecular medicine in ophthalmic care.
Topics: Administration, Oral; Aged, 80 and over; Automobile Driving; Drug Combinations; Flavonoids; Humans; Lipofuscin; Male; Mental Health; Night Blindness; Ophthalmology; Phenols; Polyphenols; Recovery of Function; Resveratrol; Retina; Retinal Pigment Epithelium; Stilbenes; Vision, Ocular | 2009 |
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Drug Resistance; Enzyme Inhibitors; Fibroblasts; Glucose Intolerance; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondria; Muscle, Skeletal; NAD; Resveratrol; Sirtuin 1; Stilbenes; Weight Loss | 2010 |
Resveratrol: a multifunctional compound improving endothelial function. Editorial to: "Resveratrol supplementation gender independently improves endothelial reactivity and suppresses superoxide production in healthy rats" by S. Soylemez et al.
Topics: Acetylation; Antioxidants; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Receptors, Estrogen; Resveratrol; Sex Factors; Stilbenes; Vasodilation; Wine | 2009 |
Anti-inflammatory effect of resveratrol by inhibition of IL-8 production in LPS-induced THP-1 cells.
Topics: Anti-Inflammatory Agents; Blotting, Western; Cell Line; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; I-kappa B Proteins; Interleukin-8; Lipopolysaccharides; Monocytes; Morus; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Plant Extracts; Polyphenols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2009 |
Resveratrol (trans-3,5,4'-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kappaB activation to abrogate dextran sulfate sodium-induced colitis.
Topics: Administration, Oral; Animals; CD4 Lymphocyte Count; Colitis; Colon; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Down-Regulation; Female; Intestinal Mucosa; Lymph Nodes; Macrophages; Mesentery; Mice; Mice, Inbred C57BL; Mucous Membrane; NF-kappa B; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Resveratrol prevents the development of pathological cardiac hypertrophy and contractile dysfunction in the SHR without lowering blood pressure.
Topics: Aging; Animals; Antioxidants; Blood Pressure; Cardiomegaly; Echocardiography; Heart Function Tests; Hypertension; Lipid Peroxidation; Male; Myocardial Contraction; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Resveratrol; Stilbenes | 2010 |
Comparative deacetylase activity of wild type and mutants of SIRT1.
Topics: Escherichia coli; Humans; Protein Conformation; Recombinant Proteins; Resveratrol; Sequence Deletion; Sirtuin 1; Stilbenes | 2010 |
Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Eukaryotic Initiation Factor-2; Heat-Shock Proteins; Humans; Protein Folding; Protein Splicing; Regulatory Factor X Transcription Factors; Resveratrol; Stilbenes; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1 | 2010 |
The anti-inflammatory activity of the polyphenol resveratrol may be partially related to inhibition of tumour necrosis factor-alpha (TNF-alpha) pre-mRNA splicing.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Fish Proteins; Flatfishes; Flavonoids; Interleukin-1beta; Kidney; Leukocytes; Phenols; Polyphenols; Polysaccharides; Resveratrol; RNA Precursors; RNA Splicing; Stilbenes; Tumor Necrosis Factor-alpha; Ulva | 2010 |
Actions of redox-active compound resveratrol under hydrogen peroxide insult in C6 astroglial cells.
Topics: Animals; Antioxidants; Ascorbic Acid; Astrocytes; Cell Line; Cell Survival; Coloring Agents; DNA Damage; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Lipids; Micronucleus Tests; Oxidants; Oxidation-Reduction; Rats; Resveratrol; Stilbenes; Tars; Tetrazolium Salts; Thiazoles | 2010 |
Resveratrol down-regulates survivin and induces apoptosis in human multidrug-resistant SPC-A-1/CDDP cells.
Topics: Animals; Apoptosis; Cell Cycle; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Mice; Mice, Nude; Microtubule-Associated Proteins; Resveratrol; Stilbenes; Survivin | 2010 |
Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway.
Topics: Animals; Apoptosis; Autophagy; Cardiotonic Agents; Carrier Proteins; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Intracellular Signaling Peptides and Proteins; Male; Myoblasts, Cardiac; Myocardium; Phosphorylation; Protein Serine-Threonine Kinases; Rapamycin-Insensitive Companion of mTOR Protein; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Transcription Factors | 2010 |
Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke.
Topics: Apoptosis; Benzopyrenes; Caspase 3; Caspase 7; Caspase 9; Cell Line; Cell Survival; Genistein; Humans; Memantine; Reactive Nitrogen Species; Reactive Oxygen Species; Resveratrol; Retinal Pigment Epithelium; Smoking; Stilbenes | 2010 |
[Protective effect of resveratrol on apoptosis of human periodontal ligament cells in vitro].
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Survival; Flow Cytometry; Humans; Hydrogen Peroxide; In Vitro Techniques; L-Lactate Dehydrogenase; Malondialdehyde; Oxidants; Oxidative Stress; Periodontal Ligament; Resveratrol; Stilbenes; Superoxide Dismutase | 2009 |
Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells.
Topics: Endothelium, Vascular; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; MADS Domain Proteins; MAP Kinase Kinase 5; MEF2 Transcription Factors; Mitogen-Activated Protein Kinase 7; Myogenic Regulatory Factors; Resveratrol; Shear Strength; Stilbenes | 2010 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin and beta-naphthoflavone induce cellular hypertrophy in H9c2 cells by an aryl hydrocarbon receptor-dependant mechanism.
Topics: Actins; Antioxidants; beta-Naphthoflavone; Cell Line; Cell Size; Cytochrome P-450 Enzyme System; DNA Primers; DNA, Complementary; Environmental Pollutants; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Isoenzymes; Polychlorinated Dibenzodioxins; Protein Folding; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes | 2010 |
Target identification using drug affinity responsive target stability (DARTS).
Topics: Binding Sites; DNA, Complementary; Drug Delivery Systems; Proteomics; Resveratrol; Stilbenes | 2009 |
Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation.
Topics: Biomarkers; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Cells, Cultured; Dendritic Cells; Humans; Immune Tolerance; Interleukin-10; Interleukin-12; Lipopolysaccharides; Membrane Glycoproteins; Monocytes; NF-kappa B; Receptors, Cell Surface; Receptors, Immunologic; Reference Values; Resveratrol; Stilbenes | 2010 |
A theoretical study of the structure-radical scavenging activity of trans-resveratrol analogues and cis-resveratrol in gas phase and water environment.
Topics: Antioxidants; Computer Simulation; Free Radicals; Gases; Models, Molecular; Molecular Structure; Phase Transition; Quantum Theory; Resveratrol; Stilbenes; Structure-Activity Relationship; Water | 2010 |
Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy.
Topics: Animals; Antioxidants; Cardiomyopathies; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Myocardium; Myocytes, Cardiac; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sirtuin 1; Stilbenes; Streptozocin; Up-Regulation | 2010 |
FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol.
Topics: Angiogenesis Inhibitors; Antibodies, Neutralizing; Capillaries; Cell Movement; Cells, Cultured; Drug Evaluation, Preclinical; Drug Synergism; Endothelial Cells; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; MAP Kinase Kinase 1; Neovascularization, Physiologic; Oncogene Protein v-akt; Protein Kinase Inhibitors; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2010 |
Mechanisms underlying vascular effect of chronic resveratrol in streptozotocin-diabetic rats.
Topics: Administration, Oral; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypoglycemic Agents; Lipid Peroxidation; Liver; Male; Malondialdehyde; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Vasoconstrictor Agents | 2010 |
Akt downregulation by flavin oxidase-induced ROS generation mediates dose-dependent endothelial cell damage elicited by natural antioxidants.
Topics: Antioxidants; Coumaric Acids; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Flavins; Humans; Oxidative Stress; Oxidoreductases; Phosphorylation; Protein Carbonylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Regioselective lipase-catalyzed synthesis of 3-o-acyl derivatives of resveratrol and study of their antioxidant properties.
Topics: Alcaligenes; Antioxidants; Bacterial Proteins; Enzymes, Immobilized; Fungal Proteins; Kinetics; Lipase; Resveratrol; Stilbenes; Substrate Specificity | 2010 |
Cis-resveratrol glucuronidation kinetics in human and recombinant UGT1A sources.
Topics: Antioxidants; Glucuronosyltransferase; Humans; Kinetics; Microsomes; Recombinant Proteins; Resveratrol; Stilbenes | 2010 |
Physiological concentrations of dietary polyphenols regulate vascular endothelial cell expression of genes important in cardiovascular health.
Topics: Cells, Cultured; Diet; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Flavonoids; Gene Expression Regulation; Humans; Hydrogen Peroxide; Nitric Oxide Synthase Type III; Phenols; Polyphenols; Quercetin; Resveratrol; RNA, Messenger; Stilbenes | 2010 |
Synthesis of 4'-ester analogs of resveratrol and their evaluation in malignant melanoma and pancreatic cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Esters; HL-60 Cells; Humans; Melanoma; Pancreatic Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship | 2010 |
Resveratrol protects against Cisplatin-induced cardiotoxicity by alleviating oxidative damage.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Cisplatin; Creatine Kinase; Free Radical Scavengers; Heart; Humans; L-Lactate Dehydrogenase; Lipid Peroxidation; Lung Neoplasms; Male; Malondialdehyde; Myocardium; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Postsynaptic Potentials; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hypothalamus; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Inhibitory Postsynaptic Potentials; Male; Neuroprotective Agents; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome | 2010 |
Resveratrol is neuroprotective because it is not a direct activator of Sirt1-A hypothesis.
Topics: AMP-Activated Protein Kinases; Animals; Brain; Cell Death; Models, Neurological; NAD; Nerve Degeneration; Neurons; Neuroprotective Agents; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes | 2010 |
Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adipocytes, Brown; Adipogenesis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 8; Cells, Cultured; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Gene Knockdown Techniques; Insulin; Insulin Receptor Substrate Proteins; Mice; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Intersexual differences in inhibitory influence of trans-resveratrol on activity of cytochrome P450 2D2 in rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; Enzyme Inhibitors; Female; Liver; Male; Rats; Rats, Wistar; Resveratrol; Sex Characteristics; Stilbenes | 2009 |
Resveratrol induces apoptosis and cell cycle arrest of human T24 bladder cancer cells in vitro and inhibits tumor growth in vivo.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; G1 Phase; Humans; Male; Mice; Mice, Inbred BALB C; p38 Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2010 |
Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.
Topics: Animals; Antioxidants; Cells, Cultured; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucosephosphate Dehydrogenase; Hepatocytes; Insulin; Insulin Receptor Substrate Proteins; Insulin-Secreting Cells; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoenolpyruvate Carboxykinase (GTP); Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Protective effect of resveratrol on formation of membrane protein carbonyls and lipid peroxidation in erythrocytes subjected to oxidative stress.
Topics: Adult; Antioxidants; Biomarkers; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Female; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Membrane Proteins; Middle Aged; Oxidative Stress; Protein Carbonylation; Resveratrol; Stilbenes; tert-Butylhydroperoxide; Time Factors; Young Adult | 2009 |
Protective effect of resveratrol against LPS-induced extracellular lipoperoxidation in AR42J cells partly via a Myd88-dependent signaling pathway.
Topics: Animals; Antioxidants; Cell Line; Gene Expression Regulation; Interleukin-1 Receptor-Associated Kinases; Lipid Peroxidation; Lipopolysaccharide Receptors; Lipopolysaccharides; Malondialdehyde; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Pancreas; Rats; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4 | 2010 |
Protective effect of post-ischemic treatment with trans-resveratrol on cytokine production and neutrophil recruitment by rat liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemokines, CXC; Heme Oxygenase-1; Interleukin-1beta; Interleukin-6; Liver; Male; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Resveratrol preconditioning induces cellular stress proteins and is mediated via NMDA and estrogen receptors.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Pressure; Blotting, Western; Brain; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Molecular Chaperones; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, N-Methyl-D-Aspartate; Resveratrol; Stilbenes; Sympathetic Nervous System; Time Factors | 2010 |
Modulatory effects of curcumin and resveratrol on lung carcinogenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Benzopyrenes; Curcumin; Drug Therapy, Combination; Glutathione; Lipid Peroxidation; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Superoxide Dismutase | 2010 |
Consuming a diet supplemented with resveratrol reduced infection-related neuroinflammation and deficits in working memory in aged mice.
Topics: Aging; Animals; Behavior, Animal; Dietary Supplements; Gene Expression Regulation; Hippocampus; Inflammation; Interleukin-1beta; Lipopolysaccharides; Male; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred BALB C; Microglia; Nervous System; Resveratrol; Stilbenes | 2009 |
Determination and imaging of metabolites from Vitis vinifera leaves by laser desorption/ionisation time-of-flight mass spectrometry.
Topics: Plant Leaves; Resveratrol; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Vitis | 2010 |
Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Antibodies; Chemokine CCL2; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutamic Acid; Hippocampus; Interleukin-1beta; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes | 2010 |
Preformulation stability of trans-resveratrol and trans-resveratrol glucoside (Piceid).
Topics: Chromatography, High Pressure Liquid; Drug Stability; Fallopia japonica; Glucosides; Plant Extracts; Resveratrol; Stilbenes; Temperature | 2010 |
Evaluation of resveratrol oxidation in vitro and the crucial role of bicarbonate ions.
Topics: Bicarbonates; Butanols; Catalase; Catechin; Culture Media; HEPES; Hydrogen-Ion Concentration; Nitrogen; Oxidation-Reduction; Phosphates; Pyruvic Acid; Resveratrol; Sodium Bicarbonate; Stilbenes; Tromethamine; Water | 2010 |
Exacerbation of tobacco smoke mediated apoptosis by resveratrol: an unexpected consequence of its antioxidant action.
Topics: Antioxidants; Apoptosis; Bronchi; Caspase 3; Caspase 9; Cell Line; Cell Survival; Epithelial Cells; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Humans; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Smoking; Stilbenes; Up-Regulation | 2011 |
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.
Topics: Acetylation; Allosteric Regulation; Animals; Blood Glucose; Calorimetry; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Activation; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mice, Obese; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Rhodamines; Sirtuin 1; Stilbenes; Substrate Specificity; Surface Plasmon Resonance; Tumor Suppressor Protein p53 | 2010 |
An antioxidant resveratrol significantly enhanced replication of hepatitis C virus.
Topics: Antioxidants; Antiviral Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Resveratrol; Ribavirin; RNA, Viral; Stilbenes; Virus Replication; Xanthophylls | 2010 |
[Distribution study of two constituents in rat after oral administration of Smilax china extract].
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; Female; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Smilax; Stilbenes | 2009 |
Pro-ulcer effects of resveratrol in mice with indomethacin-induced gastric ulcers are reversed by L-arginine.
Topics: Animals; Antineoplastic Agents; Arginine; Cyclooxygenase 1; Cyclooxygenase 2; Indomethacin; Male; Mice; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Resveratrol; RNA, Messenger; Stilbenes; Stomach Ulcer; Ulcer; Wound Healing | 2010 |
Effects of resveratrol on proliferation and apoptosis in rat ovarian theca-interstitial cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Caspases; Cell Proliferation; Cells, Cultured; DNA Fragmentation; Female; In Situ Nick-End Labeling; Rats; Resveratrol; Stilbenes; Theca Cells | 2010 |
Downregulation of the longevity-associated protein sirtuin 1 in insulin resistance and metabolic syndrome: potential biochemical mechanisms.
Topics: Angiogenesis Inhibitors; Atherosclerosis; Carotid Arteries; Down-Regulation; Glucose; Glucose Tolerance Test; Humans; Insulin Resistance; Longevity; Metabolic Syndrome; Monocytes; Palmitic Acid; Reference Values; Resveratrol; Sirtuin 1; Stilbenes; Tunica Intima; Tunica Media | 2010 |
Cre-mediated seed-specific transgene excision in tobacco.
Topics: 2S Albumins, Plant; Brassica napus; Genetic Engineering; Germination; Glucosides; Integrases; Nicotiana; Plants, Genetically Modified; Promoter Regions, Genetic; Recombination, Genetic; Resveratrol; Seeds; Stilbenes; Transgenes | 2010 |
Differential effects of resveratrol and its naturally occurring methylether analogs on cell cycle and apoptosis in human androgen-responsive LNCaP cancer cells.
Topics: Androgen Antagonists; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Estrogen Antagonists; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Resveratrol; RNA, Messenger; Stilbenes; Structure-Activity Relationship | 2010 |
AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.
Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Animals; Autophagy; Calcium; Cytosol; Enzyme Inhibitors; Humans; Lysosomes; Male; Mice; Mice, Transgenic; Neurons; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Resveratrol prevents endothelial dysfunction and aortic superoxide production after trauma hemorrhage through estrogen receptor-dependent hemeoxygenase-1 pathway.
Topics: Animals; Antioxidants; Aorta, Thoracic; Endothelium, Vascular; Estradiol; Fulvestrant; Heme Oxygenase-1; Hemorrhage; Luminescence; Male; Mesoporphyrins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Estrogen; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Superoxides | 2010 |
Resveratrol enhances perforin expression and NK cell cytotoxicity through NKG2D-dependent pathways.
Topics: Antioxidants; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Immunity, Innate; Interleukin-2; JNK Mitogen-Activated Protein Kinases; Killer Cells, Natural; Lymphocyte Activation; MAP Kinase Signaling System; NK Cell Lectin-Like Receptor Subfamily K; Perforin; Resveratrol; RNA Interference; Stilbenes; Up-Regulation | 2010 |
Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and NADPH oxidase subunit (Nox4).
Topics: Antioxidants; Blotting, Western; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; NADPH Oxidase 4; NADPH Oxidases; Naphthoquinones; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2009 |
Resveratrol alleviates some cardiac dysfunction indexes in an SHR model of essential hypertension.
Topics: Animals; Antioxidants; Cardiomegaly; Cardiotonic Agents; Chronic Disease; Heart Diseases; Heart Failure; Hypertension; Myocardial Contraction; Rats; Rats, Inbred SHR; Resveratrol; Stilbenes | 2010 |
Resveratrol, a red wine polyphenol, attenuates lipopolysaccharide-induced oxidative stress in rat liver.
Topics: Animals; Antioxidants; Iron; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2010 |
Multidrug resistance proteins restrain the intestinal absorption of trans-resveratrol in rats.
Topics: Absorption; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Interactions; Enterocytes; Intestinal Mucosa; Intestines; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure.
Topics: Adult; Animals; Cardiomyopathy, Dilated; Cell Nucleus; Cell Survival; Cells, Cultured; Chronic Disease; Cricetinae; Disease Models, Animal; Enzyme Activation; Heart Failure; Humans; Male; Mesocricetus; Mice; Muscle Fibers, Skeletal; Myocardial Infarction; Myocytes, Cardiac; Oxidative Stress; Phenols; Plant Extracts; Rats; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2010 |
Modulation of Akt and ERK1/2 pathways by resveratrol in chronic myelogenous leukemia (CML) cells results in the downregulation of Hsp70.
Topics: Blotting, Western; Cell Line, Tumor; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; HSP70 Heat-Shock Proteins; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Microscopy, Fluorescence; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2010 |
Resveratrol and rapamycin: are they anti-aging drugs?
Topics: Aging; Animals; Anti-Bacterial Agents; Antioxidants; Clinical Trials as Topic; Humans; Longevity; Resveratrol; Signal Transduction; Sirolimus; Stilbenes | 2010 |
Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis.
Topics: Adipocytes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cells, Cultured; Cytochromes c; Death Domain Receptor Signaling Adaptor Proteins; Humans; Immunoprecipitation; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirtuin 1; Stilbenes; TNF-Related Apoptosis-Inducing Ligand | 2010 |
Resveratrol nanosuspensions for dermal application--production, characterization, and physical stability.
Topics: Administration, Topical; Antioxidants; Calorimetry, Differential Scanning; Drug Stability; Electrochemistry; Excipients; Nanoparticles; Particle Size; Resveratrol; Skin Absorption; Stilbenes; Suspensions | 2009 |
SIRT1 regulates oxidant- and cigarette smoke-induced eNOS acetylation in endothelial cells: Role of resveratrol.
Topics: Acetylation; Antioxidants; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Nicotiana; Nitric Oxide Synthase Type III; Phosphorylation; Proteasome Endopeptidase Complex; Resveratrol; Serine; Sirtuin 1; Smoke; Stilbenes | 2010 |
Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line; Cells, Cultured; Colonic Neoplasms; Drug Synergism; Female; HCT116 Cells; Humans; Mice; Mice, Nude; Molecular Sequence Data; Oligopeptides; Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; Signal Transduction; Stilbenes; Surface Plasmon Resonance; TNF-Related Apoptosis-Inducing Ligand; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Resveratrol promotes autophagic cell death in chronic myelogenous leukemia cells via JNK-mediated p62/SQSTM1 expression and AMPK activation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; AMP-Activated Protein Kinases; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Autophagy; Benzamides; Blotting, Western; Caspase Inhibitors; Caspases; Cell Survival; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Macrolides; Microscopy, Confocal; Microscopy, Electron; Piperazines; Pyrimidines; Resveratrol; RNA Interference; Sequestosome-1 Protein; Stilbenes; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases | 2010 |
Synergistic effects of combined phytochemicals and skin cancer prevention in SENCAR mice.
Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Chemoprevention; Diet; Disease Models, Animal; Drug Synergism; Ellagic Acid; Female; Genes, ras; Glucaric Acid; Grape Seed Extract; Mice; Mice, Inbred SENCAR; Mutation; Phytotherapy; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Stilbenes | 2010 |
Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal.
Topics: Chromatography, Liquid; Diabetes Complications; Diabetes Mellitus; Glucosides; Glycation End Products, Advanced; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Conformation; Polygonum; Pyruvaldehyde; Resveratrol; Stilbenes | 2010 |
Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells.
Topics: Adolescent; Animals; Antineoplastic Agents; Biotransformation; Blotting, Western; Cell Line, Tumor; Cerebellar Neoplasms; Child; Chromatography, High Pressure Liquid; Humans; Medulloblastoma; Rats; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Sulfotransferases; Young Adult | 2010 |
Increased responsiveness of human coronary artery endothelial cells in inflammation and coagulation.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antioxidants; Blood Coagulation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Plant Extracts; Resveratrol; Stilbenes; Tea; Thromboplastin | 2009 |
Antioxidant effect of trans-resveratrol, pterostilbene, quercetin and their combinations in human erythrocytes in vitro.
Topics: Antioxidants; Cell Membrane; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Erythrocytes; Glutathione; Hemolysis; Humans; Hydrogen Peroxide; Lipid Metabolism; Lipid Peroxidation; Plant Extracts; Quercetin; Resveratrol; Stilbenes | 2010 |
Portuguese winemaking residues as a potential source of natural anti-adenoviral agents.
Topics: Adenoviridae; Adenovirus Infections, Human; Antiviral Agents; Cell Line; Flavonoids; Food Industry; Fruit; Genetic Vectors; Humans; Industrial Waste; Phenols; Plant Extracts; Polyphenols; Portugal; Resveratrol; Stilbenes; Virus Replication; Vitis; Wine | 2010 |
Synthesis and vasorelaxant and platelet antiaggregatory activities of a new series of 6-halo-3-phenylcoumarins.
Topics: Animals; Chromonar; Coumarins; Female; Humans; In Vitro Techniques; Inhibitory Concentration 50; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents; Warfarin | 2010 |
Inhibition of citrinin-induced apoptotic biochemical signaling in human hepatoma G2 cells by resveratrol.
Topics: Acetylcysteine; alpha-Tocopherol; Antioxidants; Apoptosis; Caspase 3; Caspase 9; Citrinin; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Oxidative Stress; p21-Activated Kinases; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2009 |
Comparative effects of curcumin and resveratrol on aflatoxin B(1)-induced liver injury in rats.
Topics: Aflatoxin B1; Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Curcumin; gamma-Glutamyltransferase; Glutathione; Liver; Male; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2010 |
Factors influencing the production of stilbenes by the knotweed, Reynoutria x bohemica.
Topics: Biomass; Emodin; Mycorrhizae; Nitrogen; Phosphorus; Plants, Medicinal; Polygonum; Resveratrol; Soil; Stilbenes | 2010 |
Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemokine CXCL1; Heme Oxygenase-1; Hemorrhage; Intercellular Adhesion Molecule-1; Interleukin-6; Liver; Male; Peroxidase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Up-Regulation | 2010 |
Evaluation of anti-invasion effect of resveratrol and related methoxy analogues on human hepatocarcinoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Neoplasm Invasiveness; Resveratrol; Stilbenes | 2010 |
Inhibitory effect of resveratrol derivative BTM-0512 on high glucose-induced cell senescence involves dimethylaminohydrolase/asymmetric dimethylarginine pathway.
Topics: Amidohydrolases; Antioxidants; Arginine; Cell Culture Techniques; Cell Line; Cellular Senescence; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Gene Expression; Glucose; Humans; Nitric Oxide; Nitric Oxide Synthase; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirtuin 1; Stilbenes | 2010 |
Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis, Ulcerative; Colon; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Female; Intramolecular Oxidoreductases; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Organ Size; p38 Mitogen-Activated Protein Kinases; Prostaglandin-E Synthases; Random Allocation; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Downregulation of cyclin D1 is associated with decreased levels of p38 MAP kinases, Akt/PKB and Pak1 during chemopreventive effects of resveratrol in liver cancer cells.
Topics: Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Flow Cytometry; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Microscopy, Confocal; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Red wine coming up roses for intestinal ischemia reperfusion injury: role for resveratrol?
Topics: Animals; Antioxidants; Disease Models, Animal; Humans; Intestine, Small; Liver; Oxidative Stress; Rats; Reperfusion Injury; Resveratrol; Stilbenes; Wine | 2009 |
Biological effects on granulosa cells of hydroxylated and methylated resveratrol analogues.
Topics: Angiogenesis Inhibitors; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Estradiol; Female; Granulosa Cells; Hydrogen Peroxide; Hydroxylation; Methylation; Osmolar Concentration; Ovarian Follicle; Oxidoreductases; Progesterone; Resveratrol; Stilbenes; Superoxides; Sus scrofa; Vascular Endothelial Growth Factors | 2010 |
Resveratrol, genistein, and curcumin bind bovine serum albumin.
Topics: Animals; Cattle; Circular Dichroism; Curcumin; Genistein; Hydrophobic and Hydrophilic Interactions; Protein Binding; Protein Denaturation; Protein Structure, Secondary; Resveratrol; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2010 |
Resveratrol, thyroid cancer, and iodide: drink up?
Topics: Animals; Humans; Iodides; Rats; Resveratrol; Stilbenes; Symporters; Thyroid Gland; Thyroid Neoplasms | 2010 |
Resveratrol increases iodide trapping in the rat thyroid cell line FRTL-5.
Topics: Animals; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Iodides; Rats; Resveratrol; Stilbenes; Symporters; Thyroid Gland; Thyrotropin | 2010 |
Resveratrol and piceatannol inhibit iNOS expression and NF-kappaB activation in dextran sulfate sodium-induced mouse colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colonic Neoplasms; Dextran Sulfate; DNA-Binding Proteins; Down-Regulation; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; I-kappa B Kinase; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Phosphorylation; Resveratrol; STAT3 Transcription Factor; Stilbenes; Time Factors | 2009 |
Liquid chromatographic/electrospray ionization mass spectrometric identification of the oxidation end-products of trans-resveratrol in aqueous solutions.
Topics: Benzaldehydes; Chromatography, Liquid; Gamma Rays; Hydroxybenzoates; Oxidation-Reduction; Resorcinols; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Water | 2010 |
Inhibition of S6K by resveratrol: in search of the purpose.
Topics: Aging; Aneurysm, Infected; Antioxidants; Humans; Plant Diseases; Resveratrol; Ribosomal Protein S6 Kinases; Stilbenes; Vitis | 2009 |
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.
Topics: Animals; Autophagy; Cell Line; Humans; Mice; Quercetin; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Stilbenes | 2009 |
dSir2 mediates the increased spontaneous physical activity in flies on calorie restriction.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Drosophila; Drosophila Proteins; Female; Gene Expression Regulation; Genotype; Histone Deacetylases; Longevity; Male; Motor Activity; Resveratrol; Sirtuins; Stilbenes | 2009 |
Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease.
Topics: Animals; Antioxidants; Disease Models, Animal; Dopamine; Enzymes; Free Radicals; Glutathione; Lipid Peroxidation; Male; Nerve Degeneration; Neurotoxins; Oxidative Stress; Oxidopamine; Parkinsonian Disorders; Phospholipases A2; Rats; Rats, Wistar; Resveratrol; Stilbenes; Substantia Nigra; Thiobarbituric Acid Reactive Substances; Treatment Outcome | 2010 |
Effect of resveratrol on the development of porcine embryos produced in vitro.
Topics: Animals; Apoptosis; Blastocyst; Caspase 3; Developmental Biology; DNA Fragmentation; Embryo, Mammalian; Enzyme Inhibitors; Fertilization in Vitro; In Vitro Techniques; Models, Biological; Oocytes; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Swine | 2010 |
SIRT1 negatively regulates the mammalian target of rapamycin.
Topics: Animals; Antioxidants; Blotting, Western; Cell Line; Cells, Cultured; Fibroblasts; HeLa Cells; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mice; Mice, Knockout; Models, Biological; Niacinamide; Protein Binding; Protein Serine-Threonine Kinases; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2010 |
Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Gefitinib; Naproxen; Quinazolines; Rats; Rats, Inbred F344; Research Design; Resveratrol; Stilbenes; Urinary Bladder Neoplasms | 2010 |
Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Anti-Inflammatory Agents; Culture Media, Conditioned; Gene Expression Regulation; Glucose; Inflammation; Insulin; Insulin Resistance; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Effects of resveratrol supplementation on cryopreservation medium of human semen.
Topics: Adult; Antioxidants; Catalase; Cryopreservation; Cryoprotective Agents; Humans; Infertility, Male; Male; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Semen; Semen Analysis; Semen Preservation; Stilbenes; Young Adult | 2010 |
SIRT1 takes a backseat to AMPK in the regulation of insulin sensitivity by resveratrol.
Topics: AMP-Activated Protein Kinases; Animals; Cardiovascular Diseases; Enzyme Inhibitors; Humans; Insulin Resistance; Obesity; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Dual targeting of the antagonistic pathways mediated by Sirt1 and TXNIP as a putative approach to enhance the efficacy of anti-aging interventions.
Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Cells, Cultured; Dehydroepiandrosterone; Gene Expression Regulation; Glucose; Humans; Mice; Rats; Resveratrol; Sirtuin 1; Stilbenes; Thioredoxins | 2009 |
Differential effects of resveratrol and novel resveratrol derivative, HS-1793, on endoplasmic reticulum stress-mediated apoptosis and Akt inactivation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Caspase Inhibitors; Caspases, Initiator; Cell Proliferation; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Heat-Shock Proteins; HT29 Cells; Humans; Naphthols; Phosphorylation; Proto-Oncogene Proteins c-akt; Regulatory Factor X Transcription Factors; Resorcinols; Resveratrol; RNA Splicing; RNA, Messenger; Signal Transduction; Stilbenes; Stress, Physiological; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1 | 2010 |
Quantitative structure-antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4'-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4'-O-beta-D-glucopy
Topics: Dimerization; Free Radical Scavengers; Glucose; Glucosides; Glucuronides; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Resveratrol; Stereoisomerism; Stilbenes | 2010 |
NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Cyclooxygenase 2; Diabetic Neuropathies; I-kappa B Proteins; Interleukin-6; Male; Malondialdehyde; Neuroprotective Agents; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
GSK/Sirtris compounds dogged by assay artifacts.
Topics: Animals; Drug Industry; Humans; Longevity; Mice; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Determination of trans- and cis-resveratrol in Serbian commercial wines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Resveratrol; Serbia; Solid Phase Extraction; Stilbenes; Wine | 2010 |
Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-X Protein; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes; Transplantation, Heterologous | 2010 |
Evolution of resveratrol and piceid contents during the industrial winemaking process of sherry wine.
Topics: Fermentation; Food Industry; Glucosides; Industrial Microbiology; Resveratrol; Stilbenes; Vitis; Wine | 2010 |
Involvement of breast cancer resistance protein (BCRP1/ABCG2) in the bioavailability and tissue distribution of trans-resveratrol in knockout mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Breast Neoplasms; Disease Models, Animal; Female; Humans; Mice; Mice, Knockout; Resveratrol; Stilbenes; Tissue Distribution | 2010 |
Prominent chemopreventive and chemoenhancing effects for resveratrol: unraveling molecular targets and the role of C-reactive protein.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; C-Reactive Protein; Carcinoma, Ehrlich Tumor; Cisplatin; Female; Leukocyte Count; Malondialdehyde; Mice; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Prevention of lipopolysaccharide-induced mouse lethality by resveratrol.
Topics: Animals; Catalase; Iron; Lipid Peroxidation; Lipopolysaccharides; Male; Mice; Nitric Oxide; Oxidative Stress; Resveratrol; Stilbenes | 2010 |
Resveratrol induces DNA double-strand breaks through human topoisomerase II interaction.
Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glioma; Histones; Humans; Phosphorylation; Resveratrol; Stilbenes; Topoisomerase II Inhibitors | 2010 |
Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats.
Topics: Animals; Antioxidants; Cytokines; Diabetes Mellitus, Experimental; Gliclazide; Hepatocytes; Hyperglycemia; Hypoglycemic Agents; Inflammation Mediators; Male; Microscopy, Electron, Transmission; Models, Biological; Niacinamide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2010 |
Resveratrol, a natural polyphenolic compound, inhibits cholera toxin-induced cyclic AMP accumulation in Vero cells.
Topics: ADP Ribose Transferases; Animals; Chlorocebus aethiops; Cholera Toxin; Cyclic AMP; Endocytosis; Enzyme Inhibitors; Flavonoids; Membrane Microdomains; Osmolar Concentration; Phenols; Polyphenols; Resveratrol; Stilbenes; Time Factors; Vero Cells | 2010 |
QSAR analysis of diaryl COX-2 inhibitors: comparison of feature selection and train-test data selection methods.
Topics: Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Least-Squares Analysis; Quantitative Structure-Activity Relationship; Regression Analysis; Reproducibility of Results; Resveratrol; Stilbenes | 2010 |
Resveratrol suppresses colitis and colon cancer associated with colitis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Cell Separation; Colitis; Colonic Neoplasms; Female; Flow Cytometry; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Precancerous Conditions; Resveratrol; Stilbenes; T-Lymphocytes | 2010 |
Resveratrol attenuates renal hypertrophy in early-stage diabetes by activating AMPK.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Diabetic Nephropathies; Hypertrophy; Kidney; Male; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Fasting; Hyperglycemia; Inflammation Mediators; Insulin; Insulin-Secreting Cells; Lipid Peroxides; Male; Niacinamide; Nitric Oxide; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin; Transcription Factor RelA | 2010 |
Resveratrol arrests and regresses the development of pressure overload- but not volume overload-induced cardiac hypertrophy in rats.
Topics: Animals; Antioxidants; Cardiomegaly; Disease Models, Animal; Heart; Lipid Peroxidation; Male; Myocardium; Oxidative Stress; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Ventricular Pressure | 2010 |
Sirt1 activation protects the mouse renal medulla from oxidative injury.
Topics: Animals; Apoptosis; Cells, Cultured; Cyclooxygenase 2; Fibrosis; Heterocyclic Compounds, 4 or More Rings; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Ureteral Obstruction | 2010 |
Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.
Topics: Antioxidants; Cell Death; Cell Line; Cell Survival; Cholesterol; Cytokines; Cytoprotection; Humans; Inflammation; Phospholipids; Reactive Oxygen Species; Resveratrol; Retina; Stilbenes; Vascular Endothelial Growth Factor A; Wine | 2010 |
Considerable increase in resveratrol production by recombinant industrial yeast strains with use of rich medium.
Topics: Acyl Coenzyme A; Acyltransferases; Arabidopsis; Arabidopsis Proteins; Brazil; Culture Media; DNA, Recombinant; Industrial Microbiology; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Vitis | 2010 |
[Protective effects of resveratrol on neonatal rat cardiomyocyte lesion induced by hypoxia].
Topics: Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Hypoxia-Inducible Factor 1, alpha Subunit; L-Lactate Dehydrogenase; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Resveratrol-mediated reversal of doxorubicin resistance in acute myeloid leukemia cells via downregulation of MRP1 expression.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Fluoresceins; Gene Expression; Humans; Leukemia, Myeloid, Acute; Multidrug Resistance-Associated Proteins; Oligonucleotide Array Sequence Analysis; Resveratrol; Stilbenes | 2010 |
Antidepressant-like effect of trans-resveratrol: Involvement of serotonin and noradrenaline system.
Topics: Animals; Antidepressive Agents; Antioxidants; Apomorphine; Behavior, Animal; Brain Chemistry; Depression; Dose-Response Relationship, Drug; Fenclonine; Hindlimb Suspension; Hypothermia; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Norepinephrine; Resveratrol; Serotonin; Stereotyped Behavior; Stilbenes; Swimming | 2010 |
Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric diet.
Topics: Adipose Tissue; Adiposity; Animal Feed; Animals; Anti-Obesity Agents; Body Weight; Dietary Fats; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors | 2009 |
Resveratrol from transgenic alfalfa for prevention of aberrant crypt foci in mice.
Topics: Animals; Azoxymethane; Body Weight; Chromatography, High Pressure Liquid; Colonic Neoplasms; Eating; Female; Glucosides; Lactase-Phlorizin Hydrolase; Medicago sativa; Mice; Plants, Genetically Modified; Precancerous Conditions; Resveratrol; Stilbenes | 2010 |
Bcl-2 modulates resveratrol-induced ROS production by regulating mitochondrial respiration in tumor cells.
Topics: Apoptosis; Cell Line, Tumor; Humans; Mitochondria; Neoplasms; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Stilbenes | 2010 |
Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation.
Topics: Analysis of Variance; Animals; Apoptosis; bcl-Associated Death Protein; Benzamides; Blood Vessels; Brain; Carbazoles; Caspase 3; Cell Survival; Cells, Cultured; Cytochromes c; DNA Fragmentation; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Forkhead Box Protein O3; Forkhead Transcription Factors; Glucose; Male; Mitochondria; Naphthols; Phosphatidylserines; Protein Transport; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Subcellular Fractions | 2010 |
Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation.
Topics: Adenylate Kinase; Animals; Antioxidants; Atherosclerosis; Cholesterol; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Homeostasis; Humans; Lipid Metabolism; Macrophages; PPAR gamma; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Resveratrol; Stilbenes | 2010 |
Bioactivity-guided separation of anti-acidogenic substances against Streptococcus mutans UA 159 from Polygonum cuspidatum.
Topics: Acids; Anthracenes; Cariostatic Agents; Chelating Agents; Chemical Fractionation; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Emodin; Fallopia japonica; Glucosides; Glycolysis; Glycosides; Humans; Hydrogen-Ion Concentration; Materials Testing; Phenols; Plant Extracts; Resveratrol; Sodium Fluoride; Stilbenes; Streptococcus mutans | 2010 |
Retinal protective effects of resveratrol via modulation of nitric oxide synthase on oxygen-induced retinopathy.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Humans; Infant, Newborn; Nitric Oxide Synthase; Oxygen; Rats; Rats, Sprague-Dawley; Resveratrol; Retina; Retinopathy of Prematurity; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Stilbenes | 2010 |
Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1.
Topics: Analysis of Variance; Animals; Blotting, Western; Cerebral Cortex; Dose-Response Relationship, Drug; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Resveratrol; Statistics, Nonparametric; Stilbenes; Time Factors | 2010 |
Redox regulation of sirtuin-1 by S-glutathiolation.
Topics: Cell Line; Cysteine; Disulfides; Glutathione; Humans; Nitroso Compounds; Oxidation-Reduction; Proteins; Resveratrol; S-Nitrosoglutathione; Sirtuin 1; Stilbenes | 2010 |
Neuron dysfunction is induced by prion protein with an insertional mutation via a Fyn kinase and reversed by sirtuin activation in Caenorhabditis elegans.
Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Death; Cell Membrane; Cells, Cultured; Cerebellum; Endopeptidase K; Humans; Mechanoreceptors; Mice; Mutagenesis, Insertional; Neurons; Neuroprotective Agents; Prions; Proto-Oncogene Proteins c-fyn; Resveratrol; Sirtuins; src-Family Kinases; Stilbenes; Touch | 2010 |
Structural determinants of resveratrol for cell proliferation inhibition potency: experimental and docking studies of new analogs.
Topics: Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colchicine; DNA; Humans; Hydroxides; Models, Molecular; Resveratrol; Stereoisomerism; Stilbenes; Tubulin | 2010 |
Comparative study of potential endothelioprotectors and impaza in modeled nitric oxide deficiency.
Topics: Animals; Antibodies; Antihypertensive Agents; Antioxidants; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2009 |
Old and new inhibitors of quinone reductase 2.
Topics: Animals; Base Sequence; DNA Primers; Enzyme Inhibitors; Furans; Humans; In Vitro Techniques; Kinetics; Melatonin; Pyridines; Pyrrolizidine Alkaloids; Quinone Reductases; Receptors, Melatonin; Recombinant Proteins; Resveratrol; Spodoptera; Stilbenes; Substrate Specificity | 2010 |
3,3',4,5,5'-Pentahydroxy-trans-stilbene, a resveratrol derivative, induces apoptosis in colorectal carcinoma cells via oxidative stress.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Colorectal Neoplasms; Cytoplasm; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Glutathione; HT29 Cells; Humans; Nucleosomes; Oxidative Stress; Poly(ADP-ribose) Polymerases; Resveratrol; Stilbenes; Tumor Cells, Cultured; Up-Regulation | 2010 |
The roles of bioactive sphingolipids in resveratrol-induced apoptosis in HL60: acute myeloid leukemia cells.
Topics: Amino Alcohols; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Caspase 3; Cell Proliferation; Ceramides; Colorimetry; Drug Synergism; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Membrane Proteins; Morpholines; Neoplasm Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sphingolipids; Stilbenes; Tumor Suppressor Proteins | 2011 |
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Chemoprevention; Cyclooxygenase 2; Diethylnitrosamine; Female; HSP70 Heat-Shock Proteins; Humans; Inflammation; Liver; Liver Neoplasms; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Myeloperoxidase-induced genomic DNA-centered radicals.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Cell Line; Cell Line, Tumor; Coculture Techniques; Cyclic N-Oxides; DNA; DNA Adducts; Free Radicals; Glutathione; Halogenation; HL-60 Cells; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Resveratrol; Stilbenes | 2010 |
Design, synthesis and anticancer activities of stilbene-coumarin hybrid compounds: Identification of novel proapoptotic agents.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Line, Tumor; Chimera; Coumarins; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Oxides; Resveratrol; Stilbenes; Structure-Activity Relationship | 2010 |
Ascorbate synthesis pathway: dual role of ascorbate in bone homeostasis.
Topics: Animals; Antioxidants; Ascorbic Acid; Bone and Bones; Cell Proliferation; Flavonoids; Homeostasis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Biological; Osteoblasts; Osteoporosis; Plant Extracts; Resveratrol; Stilbenes | 2010 |
Immunosuppressive resveratrol aneuploids from Hopea chinensis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Circular Dichroism; Dipterocarpaceae; Heterocyclic Compounds, 4 or More Rings; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Stems; Resveratrol; Stilbenes | 2010 |
Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2.
Topics: Animals; Antioxidants; Apoptosis; Cardiovascular Diseases; Cells, Cultured; Coronary Vessels; Cytoprotection; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Femoral Artery; Genes, Reporter; Glucose; Glutathione Synthase; Heme Oxygenase-1; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Male; Mice; Mice, Inbred ICR; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Response Elements; Resveratrol; RNA Interference; Stilbenes; Transcriptional Activation; Transfection; Vasodilation | 2010 |
The protective effect of resveratrol on dimethylnitrosamine-induced liver fibrosis in rats.
Topics: Animals; Antioxidants; Biomarkers; Body Weight; Dimethylnitrosamine; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Organ Size; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Resveratrol inhibits neuronal apoptosis and elevated Ca2+/calmodulin-dependent protein kinase II activity in diabetic mouse retina.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Blotting, Western; Body Weight; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Count; Diabetes Mellitus, Experimental; Down-Regulation; Enzyme Inhibitors; In Situ Nick-End Labeling; Male; Mice; Phosphorylation; Resveratrol; Retina; Retinal Ganglion Cells; Signal Transduction; Statistics, Nonparametric; Stilbenes | 2010 |
Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Genes; Heart; Humans; Hypertension; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Resveratrol; Stilbenes | 2010 |
Dysregulated calcium homeostasis and oxidative stress in chronic myeloid leukemia (CML) cells.
Topics: Adenosine Triphosphate; Adult; Calcium; Female; Homeostasis; Humans; Intracellular Space; Ionomycin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Oxidative Stress; Resveratrol; Stilbenes; Superoxide Dismutase | 2010 |
Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells.
Topics: Animals; Cell Differentiation; Cytoplasm; Immunoblotting; Immunohistochemistry; NAD; Nerve Growth Factors; Neurites; PC12 Cells; Rats; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Taming the beast within: resveratrol suppresses colitis and prevents colon cancer.
Topics: Aging; Animals; Colitis; Colonic Neoplasms; Humans; Inflammation Mediators; Mice; NF-kappa B; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
AMP-activated protein kinase mediates activity-dependent regulation of peroxisome proliferator-activated receptor gamma coactivator-1alpha and nuclear respiratory factor 1 expression in rat visual cortical neurons.
Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blindness; Cells, Cultured; Enzyme Activation; Female; Gene Expression Regulation; Male; Membrane Potentials; Mitochondria; Neurons; Nuclear Respiratory Factors; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Resveratrol; Ribonucleotides; RNA-Binding Proteins; RNA, Messenger; Stilbenes; Transcription Factors; Visual Cortex | 2010 |
Formulation and optimization of zinc-pectinate beads for the controlled delivery of resveratrol.
Topics: Absorption; Capsules; Delayed-Action Preparations; Diffusion; Drug Compounding; Pectins; Resveratrol; Stilbenes; Vasodilator Agents | 2010 |
Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention.
Topics: Antiviral Agents; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Binding Sites; Calorimetry, Differential Scanning; Cell Line; Databases, Factual; Humans; Ligands; Membrane Proteins; Models, Molecular; Mutation; Peptide Fragments; Phenols; Protein Structure, Tertiary; Proto-Oncogene Proteins; Resveratrol; Stilbenes; Structure-Activity Relationship; Thermodynamics; Ultracentrifugation; Vaccinia virus; Viral Proteins; Virulence Factors | 2010 |
Interaction of PGHS-2 and glutamatergic mechanisms controlling the ovine fetal hypothalamus-pituitary-adrenal axis.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; D-Aspartic Acid; Female; Fetus; Hydrocortisone; Hypothalamus; Isoenzymes; N-Methylaspartate; Neurosecretory Systems; Parturition; Pituitary-Adrenal System; Pregnancy; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Resveratrol; Sheep; Stilbenes; Sulfonamides | 2010 |
Hypomethylation and induction of retinoic acid receptor beta 2 by concurrent action of adenosine analogues and natural compounds in breast cancer cells.
Topics: Adenosine; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cholecalciferol; Cladribine; DNA Methylation; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Promoter Regions, Genetic; Receptors, Retinoic Acid; Resveratrol; Stilbenes; Transcriptional Activation; Tretinoin; Vidarabine | 2010 |
Pleiotropic mechanisms facilitated by resveratrol and its metabolites.
Topics: Animals; Anticarcinogenic Agents; Catalytic Domain; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Mice; Models, Molecular; Quinone Reductases; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Ameliorative effect of a combination of vitamin E, vitamin C, alpha-lipoic acid and stilbene resveratrol on lindane induced toxicity in mice olfactory lobe and cerebrum.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Butyrylcholinesterase; Catalase; Child; Cholesterol; Hexachlorocyclohexane; Humans; Infant; Insecticides; Male; Mice; Neuroprotective Agents; Olfactory Pathways; Resveratrol; Stilbenes; Superoxide Dismutase; Thioctic Acid; Vitamin E | 2010 |
Structures of two novel trimeric stilbenes obtained by horseradish peroxidase catalyzed biotransformation of trans-resveratrol and (-)-epsilon-viniferin.
Topics: Benzofurans; Catalysis; Horseradish Peroxidase; Molecular Structure; Resorcinols; Resveratrol; Stilbenes | 2010 |
Beta-arrestin 2 modulates resveratrol-induced apoptosis and regulation of Akt/GSK3ß pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Arrestins; beta-Arrestin 2; beta-Arrestins; Caspase 3; Cell Line, Tumor; Endometrial Neoplasms; Enzyme Activation; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA Interference; Signal Transduction; Stilbenes | 2010 |
AMPK- and p62/SQSTM1-dependent autophagy mediate resveratrol-induced cell death in chronic myelogenous leukemia.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Cell Line, Tumor; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Models, Biological; Resveratrol; Stilbenes | 2010 |
Resveratrol enhances the sensitivity of cholangiocarcinoma to chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cholangiocarcinoma; Cytochrome P-450 Enzyme System; Deoxycytidine; Fluorouracil; Gemcitabine; Mice; Mice, Nude; Mitomycin; Resveratrol; Stilbenes | 2010 |
Effect of prior treatment with resveratrol on density and structure of rat long bones under tail-suspension.
Topics: Animals; Bone Density; Femur; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tibia; X-Ray Microtomography | 2011 |
Resveratrol inhibits human lung adenocarcinoma cell metastasis by suppressing heme oxygenase 1-mediated nuclear factor-kappaB pathway and subsequently downregulating expression of matrix metalloproteinases.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Gene Silencing; Heme Oxygenase-1; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Neoplasm Invasiveness; NF-kappa B; Osmolar Concentration; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes | 2010 |
Total synthesis and biological evaluation of the resveratrol-derived polyphenol natural products hopeanol and hopeahainol A.
Topics: Antineoplastic Agents; Biological Products; Cholinesterase Inhibitors; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Phenols; Polyphenols; Resveratrol; Stilbenes | 2010 |
Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner.
Topics: Adipocytes; Adipose Tissue; Anti-Inflammatory Agents, Non-Steroidal; Caloric Restriction; Cell Differentiation; Cell Division; Codon, Nonsense; Cytokines; DNA Primers; DNA Replication; Glucose; Humans; Inverted Repeat Sequences; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sirtuin 1; Stilbenes; Thymidine; Vitis | 2010 |
Aryl hydrocarbon receptor antagonists attenuate the deleterious effects of benzo[a]pyrene on isolated rat follicle development.
Topics: Animals; Anti-Mullerian Hormone; Benzo(a)pyrene; Cells, Cultured; Estradiol; Female; Flavones; Ovarian Follicle; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2010 |
Endothelial Nrf2 activation: a new target for resveratrol?
Topics: Animals; Antioxidants; Apoptosis; Cardiovascular Diseases; Cytoprotection; Endothelial Cells; Humans; Mice; NF-E2-Related Factor 2; Oxidative Stress; Response Elements; Resveratrol; Stilbenes; Transcriptional Activation; Vasodilation | 2010 |
Resveratrol regulates pathologic angiogenesis by a eukaryotic elongation factor-2 kinase-regulated pathway.
Topics: Adenylate Kinase; Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Cell Proliferation; Cells, Cultured; Elongation Factor 2 Kinase; Endothelial Cells; Eye; Lasers; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2010 |
Resveratrol ameliorates vasculopathy in STZ-induced diabetic rats: role of AGE-RAGE signalling.
Topics: Analysis of Variance; Animals; Aorta; Blood Glucose; Blotting, Western; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Immunohistochemistry; Insulin; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Cytotoxic effect of wine polyphenolic extracts and resveratrol against human carcinoma cells and normal peripheral blood mononuclear cells.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cytotoxins; Female; Flavonoids; Humans; Leukocytes, Mononuclear; Phenols; Polyphenols; Resveratrol; Stilbenes; Uterine Cervical Neoplasms; Wine | 2010 |
Calpain and caspase orchestrated death signal to accomplish apoptosis induced by resveratrol and its novel analog hydroxystilbene-1 [correction of hydroxstilbene-1] in cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Calcium; Calpain; Cardiolipins; Caspases; Cell Line, Tumor; Cytochromes c; Cytosol; Humans; Membrane Potential, Mitochondrial; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Inhibition of neointimal formation by trans-resveratrol: role of phosphatidyl inositol 3-kinase-dependent Nrf2 activation in heme oxygenase-1 induction.
Topics: Animals; Aorta, Thoracic; Arterial Occlusive Diseases; Cell Line; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclin D; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Femoral Artery; Heme Oxygenase-1; Hyperplasia; Membrane Proteins; Mice; Muscle, Smooth, Vascular; Neointima; NF-E2-Related Factor 2; Phosphoinositide-3 Kinase Inhibitors; Protein Transport; Rats; Reactive Oxygen Species; Resveratrol; Retinoblastoma Protein; Stilbenes | 2010 |
Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis.
Topics: Animals; Benzoates; Binding Sites; Cell Line; Cell Membrane; Cholesterol; Cholesterol Oxidase; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Electrochemical Techniques; Epithelial Cells; Genotype; Humans; Hydroxymethylglutaryl-CoA Synthase; Kinetics; Mass Spectrometry; Mice; Mice, Inbred CFTR; Microelectrodes; Mutation; Nasal Mucosa; Phenotype; Promoter Regions, Genetic; Respiratory Mucosa; Resveratrol; Stilbenes; Thiazolidines; Transfection | 2010 |
Identification of natural antimicrobial substances in red muscadine juice against Cronobacter sakazakii.
Topics: Anti-Infective Agents; Beverages; Cronobacter sakazakii; Ellagic Acid; Flavonoids; Food Handling; Food Microbiology; Food Preservatives; Fruit; Humans; Hydrogen-Ion Concentration; Infant; Infant Food; Malates; Phenols; Polyphenols; Resveratrol; Stilbenes; Tannins; Tartrates; Vitis | 2010 |
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Topics: Animals; Antioxidants; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Hyperplasia; Inflammation; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oxidative Stress; Phenobarbital; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Tyrosine | 2010 |
Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Forkhead Box Protein O3; Forkhead Transcription Factors; HT29 Cells; Humans; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Time Factors; Tumor Suppressor Protein p53; Wnt Proteins | 2010 |
A toast to your health, one drink at a time.
Topics: Adipocytes; Alcohol Drinking; Antioxidants; Cardiovascular Diseases; Humans; Metabolic Diseases; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Wine | 2010 |
Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation.
Topics: Antineoplastic Agents, Phytogenic; beta-Galactosidase; CD4 Antigens; Dose-Response Relationship, Drug; HeLa Cells; HIV Long Terminal Repeat; Humans; Immunoblotting; NAD; Nicotinamide Phosphoribosyltransferase; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation | 2010 |
Resveratrol enhances NK cell cytotoxicity: possible role for aryl hydrocarbon receptor.
Topics: Animals; Anthracenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hep G2 Cells; Humans; Killer Cells, Natural; MAP Kinase Kinase 4; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2010 |
Effects of resveratrol on expression of vascular endothelial growth factor in human gingival fibroblasts stimulated by periodontal pathogens.
Topics: Aggregatibacter actinomycetemcomitans; Analysis of Variance; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bacterial Outer Membrane Proteins; Capillary Permeability; Cattle; Cells, Cultured; Culture Media, Conditioned; Cytoplasmic Vesicles; DNA Damage; Female; Fibroblasts; Gingiva; Guinea Pigs; Humans; Immunoenzyme Techniques; Porphyromonas gingivalis; Resveratrol; RNA, Messenger; Statistics, Nonparametric; Stilbenes; Vascular Endothelial Growth Factor A | 2010 |
Suppression of oxidative stress by resveratrol after isometric contractions in gastrocnemius muscles of aged mice.
Topics: Aging; Animals; Body Weight; Citrate (si)-Synthase; Eating; Glutathione; Hydrogen Peroxide; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; NADPH Oxidases; Oxidative Stress; Resveratrol; Stilbenes; Superoxide Dismutase; Xanthine Oxidase | 2010 |
Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers.
Topics: Adrenal Medulla; Amyloid beta-Peptides; Animals; Antioxidants; Benzothiazoles; Epitopes; Microscopy, Atomic Force; Peptides; Protein Binding; Protein Conformation; Protein Folding; Protein Structure, Secondary; Rats; Resveratrol; Silver Staining; Stilbenes; Thiazoles | 2010 |
Resveratrol, purified from the stem of Vitis coignetiae Pulliat, inhibits food intake in C57BL/6J Mice.
Topics: Agouti-Related Protein; Animals; Anti-Obesity Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Eating; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Neurons; Neuropeptide Y; Plant Stems; Random Allocation; Resveratrol; Stilbenes; Vitis | 2010 |
Resveratrol impaired the morphological transition of Candida albicans under various hyphae-inducing conditions.
Topics: Candida albicans; Candidiasis; Humans; Hyphae; Resveratrol; Stilbenes | 2010 |
Resveratrol confers resistance against taxol via induction of cell cycle arrest in human cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cisplatin; Humans; Mitosis; Paclitaxel; Polymerization; Resveratrol; Signal Transduction; Stilbenes; Vinblastine | 2010 |
trans-Resveratrol reduces precancerous colonic lesions in dimethylhydrazine-treated rats.
Topics: 1,2-Dimethylhydrazine; Animals; Colon; Colonic Neoplasms; Disease Models, Animal; Humans; Male; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.
Topics: Animals; Antineoplastic Agents; Aromatase; Biphenyl Compounds; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Inhibitors; HL-60 Cells; Humans; Inhibitory Concentration 50; Macrophages; Magnetic Resonance Spectroscopy; Mice; NAD(P)H Dehydrogenase (Quinone); NF-kappa B; Nitric Oxide Synthase; Picrates; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stilbenes; Sulfuric Acid Esters | 2010 |
Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants.
Topics: Adipocytes; Adipose Tissue; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gene Expression; Humans; Inflammation; Male; Obesity; Resveratrol; RNA, Messenger; Stilbenes | 2010 |
Caloric restriction or resveratrol supplementation and ageing in a non-human primate: first-year outcome of the RESTRIKAL study in Microcebus murinus.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Cheirogaleidae; Male; Resveratrol; Stilbenes | 2011 |
Resveratrol, a red wine constituent, blocks the antimitogenic effects of estradiol on human female coronary artery smooth muscle cells.
Topics: Antimitotic Agents; Cell Proliferation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Estradiol; Female; Hormone Antagonists; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osmolar Concentration; Resveratrol; Sex Factors; Stilbenes; Vitis; Wine | 2010 |
Resveratrol treatment induces redox stress in red blood cells: a possible role of caspase 3 in metabolism and anion transport.
Topics: Anion Exchange Protein 1, Erythrocyte; Caspase 3; Erythrocytes; Humans; Models, Biological; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes | 2010 |
Resveratrol protects against protease inhibitor-induced reactive oxygen species production, reticulum stress and lipid raft perturbation.
Topics: Antioxidants; Antiretroviral Therapy, Highly Active; Cells, Cultured; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Muscle Fibers, Skeletal; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sarcoplasmic Reticulum; Stilbenes | 2010 |
Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol.
Topics: Acetylcarnitine; Animals; Antioxidants; Axons; Environmental Pollutants; Male; Nerve Degeneration; Neural Conduction; Neuroprotective Agents; Nitro Compounds; Peripheral Nervous System Diseases; Propionates; Rats; Rats, Sprague-Dawley; Resveratrol; Sciatic Nerve; Stilbenes | 2010 |
Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death.
Topics: Animals; Antioxidants; Cell Death; Cell Line; Cytoprotection; Drug Evaluation, Preclinical; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2010 |
Resveratrol modulates RTX toxin-induced cytotoxicity through interference in adhesion and toxin production.
Topics: Animals; Bacterial Adhesion; Bacterial Toxins; Down-Regulation; Gene Expression Regulation, Bacterial; HeLa Cells; Host-Pathogen Interactions; Humans; Mice; Movement; Resveratrol; RNA, Messenger; Sepsis; Stilbenes; Vibrio Infections; Vibrio vulnificus | 2010 |
Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions.
Topics: Animals; Anti-Inflammatory Agents; Dopamine; Embryo, Mammalian; Female; Flavonoids; Lipopolysaccharides; Mesencephalon; Mice; Mice, Inbred C57BL; Microglia; Mitogen-Activated Protein Kinases; NADPH Oxidases; Nerve Degeneration; Neuroglia; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinson Disease; Phenols; Polyphenols; Pregnancy; Rats; Rats, Inbred F344; Reactive Oxygen Species; Resveratrol; Stilbenes; Substantia Nigra | 2010 |
The role of the DDAH-ADMA pathway in the protective effect of resveratrol analog BTM-0512 on gastric mucosal injury.
Topics: Amidohydrolases; Animals; Anti-Ulcer Agents; Arginine; Disease Models, Animal; Ethanol; Hydroxyl Radical; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stomach Ulcer; Superoxides | 2010 |
Resveratrol and liver disease: from bench to bedside and community.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride; Cytokines; Ethanol; Free Radicals; Glutathione; Hepatocytes; Humans; Liver Diseases; NF-kappa B; Resveratrol; Stilbenes | 2010 |
Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer.
Topics: Anticarcinogenic Agents; Aromatase; Aromatase Inhibitors; Chemoprevention; Crystallography, X-Ray; Humans; Models, Molecular; Neoplasms; Quinone Reductases; Resveratrol; Stilbenes; Veratrum | 2010 |
Resveratrol attenuates behavioral impairments and reduces cortical and hippocampal loss in a rat controlled cortical impact model of traumatic brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Cell Count; Cell Death; Cerebral Cortex; Dose-Response Relationship, Drug; Hippocampus; Male; Maze Learning; Motor Activity; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease.
Topics: Adipose Tissue, Brown; Animals; Antioxidants; Disease Models, Animal; Down-Regulation; Huntington Disease; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Sirtuin 1; Stilbenes; Trans-Activators; Transcription Factors; Treatment Outcome | 2010 |
Resveratrol induces cell-cycle disruption and apoptosis in chemoresistant B16 melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Doxorubicin; Drug Resistance, Neoplasm; Melanoma, Experimental; Mice; Resveratrol; Stilbenes | 2010 |
Resveratrol restores lysophosphatidylcholine-induced loss of endothelium-dependent relaxation in rat aorta tissue coinciding with inhibition of extracellular-signal-regulated protein kinase activation.
Topics: Animals; Aorta, Thoracic; Biological Factors; Cells, Cultured; Cyclooxygenase 1; Endothelial Cells; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; In Vitro Techniques; Lysophosphatidylcholines; Male; Membrane Proteins; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2010 |
Resveratrol protects human retinal pigment epithelial cells from acrolein-induced damage.
Topics: Acrolein; Antioxidants; Cells, Cultured; Cytoprotection; Drug Synergism; Humans; Hydrogen Peroxide; Lutein; Meclofenamic Acid; Oxidative Stress; Phagocytosis; Resveratrol; Retinal Pigment Epithelium; Smoking; Stilbenes; Xanthophylls; Zeaxanthins | 2010 |
Resveratrol suppresses body mass gain in a seasonal non-human primate model of obesity.
Topics: Animals; Cheirogaleidae; Energy Intake; Energy Metabolism; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Male; Motor Activity; Pancreatic Polypeptide; Peptide YY; Resveratrol; Satiety Response; Stilbenes; Weight Gain | 2010 |
Anti-angiogenic effect of high-dose resveratrol in a swine model of metabolic syndrome.
Topics: Angiogenesis Inhibitors; Angiostatins; Animals; Antigens, CD; Cadherins; Cholesterol, Dietary; Collateral Circulation; Coronary Angiography; Disease Models, Animal; Magnetic Resonance Imaging; Male; Metabolic Syndrome; Myocardial Ischemia; Neovascularization, Physiologic; Resveratrol; Stilbenes; Swine; Swine, Miniature | 2010 |
Impact of glutaraldehyde on in vivo colon-specific release of resveratrol from biodegradable pectin-based formulation.
Topics: Absorption; Animals; Calcium Chloride; Chemistry, Pharmaceutical; Colon; Cross-Linking Reagents; Drug Carriers; Drug Compounding; Glutaral; Hydrogen-Ion Concentration; Male; Microspheres; Particle Size; Pectins; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Technology, Pharmaceutical; Time Factors | 2010 |
Growth-stimulatory effect of resveratrol in human cancer cells.
Topics: Animals; Female; Humans; Mice; Mice, Nude; Neoplasms; Nervous System Neoplasms; NF-kappa B; Nitriles; Phenols; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Sulfones | 2010 |
trans-resveratrol inhibits hyperglycemia-induced inflammation and connexin downregulation in retinal pigment epithelial cells.
Topics: Cell Line; Connexin 43; Diabetic Retinopathy; Down-Regulation; Gap Junctions; Humans; Hyperglycemia; Interleukin-6; Interleukin-8; Resveratrol; Retinal Pigment Epithelium; Stilbenes; Transforming Growth Factor beta1 | 2010 |
Natural products inhibit LPS-induced activation of pro-inflammatory cytokines in peripheral blood mononuclear cells.
Topics: Anti-Inflammatory Agents; Curcumin; Cytokines; Interleukin-1beta; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Resveratrol; Sesquiterpenes; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Piceatannol, a catechol-type polyphenol, inhibits phorbol ester-induced NF-{kappa}B activation and cyclooxygenase-2 expression in human breast epithelial cells: cysteine 179 of IKK{beta} as a potential target.
Topics: Anticarcinogenic Agents; Blotting, Western; Breast; Breast Neoplasms; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cysteine; Epithelial Cells; Female; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; I-kappa B Kinase; NF-kappa B; Phenols; Phorbol Esters; Polyphenols; Resveratrol; Stilbenes; Wound Healing | 2010 |
Protective effect of resveratrol on agonist-dependent regulation of vascular contractility via inhibition of rho-kinase activity.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Calcium; Enzyme Activators; In Vitro Techniques; Isometric Contraction; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Relaxation; Muscle, Smooth, Vascular; Phorbol Esters; Phosphorylation; Potassium Chloride; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Resveratrol; rho-Associated Kinases; Sodium Fluoride; Stilbenes; Vasodilator Agents | 2010 |
[Efficacy study in vitro: assessment of the properties of resveratrol and resveratrol + N-acetyl-cysteine on proliferation and inhibition of collagen activity].
Topics: Acetylcysteine; Cell Proliferation; Enzyme Inhibitors; Female; Fibroblasts; Humans; Matrix Metalloproteinase Inhibitors; Menopause; Resveratrol; Stilbenes | 2010 |
Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite.
Topics: Animals; Cell Line; Cell Survival; Epithelial Cells; Free Radical Scavengers; Kidney Tubules, Collecting; Mice; Molsidomine; Peroxynitrous Acid; Reactive Nitrogen Species; Resveratrol; Serum Albumin, Bovine; Stilbenes | 2010 |
Anti-tumor effects of bakuchiol, an analogue of resveratrol, on human lung adenocarcinoma A549 cell line.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Humans; Inhibitory Concentration 50; Lung Neoplasms; Membrane Potential, Mitochondrial; Mice; Osmolar Concentration; Phenols; Reactive Oxygen Species; Resveratrol; S Phase; Stilbenes; Time Factors; Tumor Suppressor Protein p53 | 2010 |
Neuroprotective effects of resveratrol: potential mechanisms.
Topics: Animals; Humans; Neuroprotective Agents; Resveratrol; Stilbenes | 2010 |
Protective potential of trans-resveratrol against 4-hydroxynonenal induced damage in PC12 cells.
Topics: Aldehydes; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cysteine Proteinase Inhibitors; Cytoprotection; Drug Antagonism; Glutathione; Lipid Peroxidation; Neurons; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Direct determination of trans-resveratrol in human plasma by spectrofluorimetry and second-order standard addition.
Topics: Animals; Calibration; Humans; Limit of Detection; Rats; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2010 |
Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule.
Topics: Animals; Brain; Heme Oxygenase-1; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes | 2010 |
Effects of nuclear factor-κB inhibitors on colon anastomotic healing in rats.
Topics: Anastomosis, Surgical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Enteritis; Hydroxyproline; Interleukin-6; Laparotomy; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Models, Animal; NF-kappa B; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Wound Healing | 2011 |
Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Down-Regulation; Enzyme Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Mice; Mice, Knockout; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Phenotype; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; Ultrasonography; Ventricular Function, Left | 2010 |
Resveratrol inhibits angiogenic response of cultured endothelial F-2 cells to vascular endothelial growth factor, but not to basic fibroblast growth factor.
Topics: Animals; Blotting, Western; Cell Line; Cyclooxygenase 2; Dinoprost; Endothelium, Vascular; Fibroblast Growth Factor 2; Mice; Neovascularization, Physiologic; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2010 |
Resveratrol inhibits dimethylnitrosamine-induced hepatic fibrosis in rats.
Topics: Alkylating Agents; Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury, Chronic; Dimethylnitrosamine; Down-Regulation; Hepatic Stellate Cells; Liver; Liver Cirrhosis; Male; Organ Size; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Transforming Growth Factor beta1; Weight Loss | 2010 |
Resveratrol reverses endothelial nitric-oxide synthase uncoupling in apolipoprotein E knockout mice.
Topics: Animals; Antioxidants; Apolipoproteins E; Biopterins; GTP Cyclohydrolase; Isoenzymes; Male; Malondialdehyde; Mice; Mice, Knockout; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes; Superoxide Dismutase; Superoxides; Tyrosine | 2010 |
Phenotypic anchoring of gene expression after developmental exposure to aryl hydrocarbon receptor ligands in zebrafish.
Topics: Abnormalities, Drug-Induced; Animals; Aorta; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Gene Expression; Growth and Development; Heart; Larva; Ligands; Phenotype; Polychlorinated Dibenzodioxins; Prostaglandin-Endoperoxide Synthases; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Stilbenes; Veins; Water Pollutants, Chemical; Zebrafish | 2010 |
A newly synthesized, potent tyrosinase inhibitor: 5-(6-hydroxy-2-naphthyl)-1,2,3-benzenetriol.
Topics: Agaricales; Animals; Enzyme Inhibitors; Kinetics; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Naphthols; Pyrogallol; Pyrones; Resveratrol; Stilbenes | 2010 |
Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD.
Topics: Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Blotting, Western; Cells, Cultured; Gene Expression Profiling; Gene Expression Regulation; Humans; Lipopolysaccharides; Luciferases; MicroRNAs; Monocytes; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-jun; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Up-Regulation | 2010 |
Antidiabetic activity of resveratrol, a known SIRT1 activator in a genetic model for type-2 diabetes.
Topics: Adiponectin; Animals; Body Weight; Chemotherapy, Adjuvant; Cholesterol; Diabetes Mellitus, Type 2; Enzyme Activation; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Mice; Resveratrol; Sirtuin 1; Stilbenes; Triglycerides | 2011 |
A single-dose resveratrol treatment in a mouse model of amyotrophic lateral sclerosis.
Topics: Acetylation; Amyotrophic Lateral Sclerosis; Animals; Body Weight; Diet; Disease Models, Animal; Longevity; Mice; Mice, Mutant Strains; Mutation; Psychomotor Performance; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2010 |
Resveratrol regulates p66Shc activation in HaCaT cells.
Topics: Antioxidants; Butadienes; Cell Death; Cell Division; Cell Line, Transformed; Enzyme Inhibitors; Humans; Keratinocytes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes | 2010 |
Antimicrobial effects of wine: separating the role of polyphenols, pH, ethanol, and other wine components.
Topics: Anti-Infective Agents; Antioxidants; Colony Count, Microbial; Escherichia coli; Ethanol; Flavonoids; Food Contamination; Food Microbiology; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Phenols; Polyphenols; Resveratrol; Salmonella enteritidis; Stilbenes; Wine | 2010 |
Mixed-mode solid-phase extraction followed by acetylation and gas chromatography mass spectrometry for the reliable determination of trans-resveratrol in wine samples.
Topics: Acetylation; Gas Chromatography-Mass Spectrometry; Limit of Detection; Resveratrol; Solid Phase Extraction; Stilbenes; Wine | 2010 |
Blockade by nanomolar resveratrol of quantal catecholamine release in chromaffin cells.
Topics: Action Potentials; Adrenal Medulla; Animals; Catecholamines; Cattle; Cells, Cultured; Chromaffin Cells; Exocytosis; Microchip Analytical Procedures; Resveratrol; Stilbenes | 2010 |
Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells.
Topics: Anticarcinogenic Agents; Basic Helix-Loop-Helix Transcription Factors; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Epigenesis, Genetic; Estradiol; Estrogen Receptor alpha; Female; Gene Silencing; Humans; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Transcription, Genetic | 2010 |
Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.
Topics: Antioxidants; Cell Movement; Cell Survival; Cells, Cultured; Coumaric Acids; Curcumin; Enzyme Inhibitors; Fibroblasts; Free Radical Scavengers; Gingiva; Humans; Nicotine; Periodontal Ligament; Phenols; Phloretin; rac GTP-Binding Proteins; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; Signal Transduction; Stilbenes; Time Factors; Wound Healing | 2010 |
Anti-oxidant effects of resveratrol on mice with DSS-induced ulcerative colitis.
Topics: Animals; Antioxidants; Base Sequence; Blotting, Western; Colitis, Ulcerative; Colon; Dextran Sulfate; DNA Primers; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Peroxidase; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2010 |
Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cells.
Topics: Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Humans; MicroRNAs; Oncogene Proteins; Resveratrol; Signal Transduction; Smad Proteins; Stilbenes; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Suppressor Proteins | 2010 |
Resveratrol protects human endothelium from H(2)O(2)-induced oxidative stress and senescence via SirT1 activation.
Topics: Animals; Antioxidants; Base Sequence; Cells, Cultured; Cellular Senescence; Coronary Artery Disease; DNA Primers; Endothelial Cells; Gene Knockdown Techniques; Humans; Hydrogen Peroxide; Oxidative Stress; Rats; Resveratrol; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2010 |
Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3.
Topics: Acetylation; Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Epithelial Cells; Fibroblasts; Fibrosis; Immunoprecipitation; Kidney; Mice; Microscopy, Confocal; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1 | 2010 |
Effects of plant polyphenols on ovarian follicular reserve in aging rats.
Topics: Aging; Animals; Body Weight; Cell Count; Drug Evaluation, Preclinical; Estrous Cycle; Female; Flavonoids; Genistein; Ovarian Follicle; Phenols; Plant Extracts; Polyphenols; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tea | 2010 |
Therapeutic effects of resveratrol during acute periods following experimental ischemic stroke.
Topics: Acute Disease; Animals; Brain Infarction; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Immunologic; Female; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes; Stroke | 2010 |
Nutraceutical inhibition of muscle proteolysis: a role of diallyl sulphide in the treatment of muscle wasting.
Topics: Allyl Compounds; Animals; Anorexia; Cachexia; Catechin; Cells, Cultured; Dietary Supplements; Genistein; Male; Muscle, Skeletal; Muscular Atrophy; Neoplasms; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfides; Weight Loss | 2011 |
Augmentation of cholinesterases and ATPase activities in the cerebellum and pons-medulla oblongata, by a combination of antioxidants (resveratrol, ascorbic acid, alpha-lipoic acid and vitamin E), in acutely lindane intoxicated mice.
Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Antioxidants; Ascorbic Acid; Butyrylcholinesterase; Cerebellum; Cholinesterases; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Insecticides; Male; Medulla Oblongata; Mice; Pons; Resveratrol; Stilbenes; Thioctic Acid; Vitamin E | 2010 |
In vitro screening for angiostatic potential of herbal chemicals.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Blotting, Western; Catechin; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chalcones; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Focal Adhesion Protein-Tyrosine Kinases; Humans; Nerve Growth Factors; Plant Preparations; Resveratrol; Retinal Pigment Epithelium; Serpins; Stilbenes; Umbilical Veins; Vascular Endothelial Growth Factor A; Xanthones | 2010 |
Resveratrol and small artery compliance and remodeling in the spontaneously hypertensive rat.
Topics: Aging; Animals; Blood Pressure; Compliance; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Resveratrol; Stilbenes; Vascular Resistance | 2010 |
Isolation, purification, and study of properties of recombinant hepsin from Escherichia coli.
Topics: Anthralin; Cell Line, Tumor; Escherichia coli; Gene Expression; Humans; Kinetics; Recombinant Proteins; Resveratrol; Serine Endopeptidases; Serine Proteinase Inhibitors; Stilbenes; Substrate Specificity | 2010 |
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.
Topics: Animals; Antioxidants; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Oxygen; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left | 2010 |
Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits.
Topics: Acetylcholine; Animals; Antioxidants; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Estrogens; Insulin; Lipid Peroxides; Lipids; Male; NADP; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rabbits; Resveratrol; Stilbenes; Superoxide Dismutase; Testosterone; Time Factors; Vascular Diseases | 2011 |
[Resveratrol inhibits EGF-induced invasion of human lung adenocarcinoma A549 cells].
Topics: Adenocarcinoma; Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Epidermal Growth Factor; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Resveratrol and its oligomers from wine grapes are selective (1)O2 quenchers: mechanistic implication by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry and theoretical calculation.
Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Oxygen; Polymers; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry; Vitis | 2010 |
Resveratrol attenuates radiation damage in Caenorhabditis elegans by preventing oxidative stress.
Topics: Animals; Animals, Genetically Modified; Antioxidants; Base Sequence; Caenorhabditis elegans; Caenorhabditis elegans Proteins; DNA Primers; DNA, Helminth; DNA, Mitochondrial; Free Radical Scavengers; Gamma Rays; Mitochondria; Oxidative Stress; Radiation-Protective Agents; Reactive Oxygen Species; Resveratrol; Sirtuins; Stilbenes; Superoxide Dismutase | 2010 |
Resveratrol content and expression of phenylalanine ammonia-lyase and stilbene synthase genes in rolC transgenic cell cultures of Vitis amurensis.
Topics: Acyltransferases; Cells, Cultured; Gene Expression Regulation, Plant; Genes, Bacterial; Multigene Family; Phenylalanine Ammonia-Lyase; Plant Proteins; Plants, Genetically Modified; Resveratrol; Rhizobium; RNA, Plant; Stilbenes; Vitis | 2010 |
Design of a pectin-based microparticle formulation using zinc ions as the cross-linking agent and glutaraldehyde as the hardening agent for colonic-specific delivery of resveratrol: in vitro and in vivo evaluations.
Topics: Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Colon; Cross-Linking Reagents; Drug Carriers; Drug Design; Drug Stability; Glutaral; Male; Microscopy, Electron, Scanning; Particle Size; Pectins; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Spectroscopy, Fourier Transform Infrared; Stilbenes; Surface Properties; Tissue Distribution | 2011 |
Medicinal mushroom Ganoderma lucidum as a potent elicitor in production of t-resveratrol and t-piceatannol in peanut calluses.
Topics: Arachis; Chromatography, High Pressure Liquid; Reishi; Resveratrol; Stilbenes | 2010 |
Antioxidant activity of resveratrol in several fish lipid matrices: effect of acylation and glucosylation.
Topics: Acylation; Animals; Antioxidants; Fishes; Glycosylation; Lipids; Resveratrol; Stilbenes | 2010 |
Effects of resveratrol on membrane biophysical properties: relevance for its pharmacological effects.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry, Differential Scanning; Fluorescent Dyes; Hydrogen-Ion Concentration; Lipid Bilayers; Membrane Fluidity; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Unilamellar Liposomes | 2010 |
Resveratrol modulates angiogenesis through the GSK3β/β-catenin/TCF-dependent pathway in human endothelial cells.
Topics: Animals; beta Catenin; Cells, Cultured; Chick Embryo; Chorioallantoic Membrane; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; TCF Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2010 |
AMP kinase acts as a negative regulator of RANKL in the differentiation of osteoclasts.
Topics: Adenylate Kinase; Animals; Apoptosis; Blotting, Western; Bone Resorption; Catechin; Cell Differentiation; Cell Survival; Cells, Cultured; Macrophage Colony-Stimulating Factor; MAP Kinase Kinase Kinases; Metformin; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Pyrazoles; Pyrimidines; RANK Ligand; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes | 2010 |
Resveratrol induces apoptosis MH7A human rheumatoid arthritis synovial cells in a sirtuin 1-dependent manner.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; bcl-X Protein; Benzamides; Caspase 3; Caspase 9; Cell Line; Cytochromes c; Humans; Mitochondria; Naphthols; Resveratrol; Sirtuin 1; Stilbenes; Synovial Membrane; Up-Regulation | 2012 |
Identification of components of grape powder with anti-apoptotic effects.
Topics: Anthocyanins; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Catechin; Cell Death; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; Food, Preserved; Freeze Drying; Fruit; Humans; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Quercetin; Reactive Oxygen Species; Resveratrol; Stilbenes; Taurodeoxycholic Acid; Vitis | 2011 |
Investigation of microbial elicitation of trans-resveratrol and trans-piceatannol in peanut callus led to the application of chitin as a potential elicitor.
Topics: Anti-Infective Agents; Arachis; Chitin; Microbial Sensitivity Tests; Resveratrol; Stilbenes | 2010 |
trans-Resveratrol downregulates Txnip overexpression occurring during liver ischemia-reperfusion.
Topics: Amidohydrolases; Animals; Antioxidants; Blotting, Western; Carrier Proteins; Cell Cycle Proteins; Down-Regulation; Injections, Intravenous; Liver; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Thioredoxin-Disulfide Reductase; Thioredoxins | 2010 |
Resveratrol prevents light-induced retinal degeneration via suppressing activator protein-1 activation.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Cells, Cultured; Disease Models, Animal; Electroretinography; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Light; Male; Mice; Mice, Inbred BALB C; Photoreceptor Cells, Vertebrate; Radiation Injuries, Experimental; Resveratrol; Retina; Retinal Degeneration; Sirtuin 1; Stilbenes; Transcription Factor AP-1 | 2010 |
Essential role of ER-alpha-dependent NO production in resveratrol-mediated inhibition of restenosis.
Topics: Animals; Carotid Arteries; Carotid Stenosis; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Estrogen Receptor alpha; Female; Mice; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Resveratrol; Secondary Prevention; Stilbenes | 2010 |
Trans- but not cis-resveratrol impairs angiotensin-II-mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated receptor-gamma upregulation.
Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Cardiovascular Diseases; Cell Communication; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Female; Humans; Inflammation Mediators; Male; NF-kappa B; Ovariectomy; PPAR gamma; Rats; Rats, Sprague-Dawley; Resveratrol; Stereoisomerism; Stilbenes; Up-Regulation | 2010 |
Resveratrol differentially modulates inflammatory responses of microglia and astrocytes.
Topics: Analysis of Variance; Animals; Astrocytes; Blotting, Western; Cell Line; Cells, Cultured; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Inflammation; Lipopolysaccharides; Mice; Microglia; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type II; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2010 |
Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia.
Topics: ADP-ribosyl Cyclase 1; Adult; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; bcl-2-Associated X Protein; Caspase 3; Cell Cycle Proteins; Cladribine; DNA-Binding Proteins; Drug Therapy, Combination; Enzyme Activation; Histones; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Membrane Glycoproteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Purines; Resveratrol; Stilbenes; Tumor Suppressor Proteins; Vidarabine; ZAP-70 Protein-Tyrosine Kinase | 2011 |
Resveratrol (3,5,4'-trihydroxystilbene) protects pregnant mother and fetus from the immunotoxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Apoptosis; Atrophy; Cell Differentiation; Cells, Cultured; Cytochrome P-450 CYP1A1; Environmental Pollutants; Female; Fetus; Gene Expression Regulation; Maternal Exposure; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Protective Agents; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; T-Lymphocyte Subsets; Thymus Gland | 2011 |
Red wine antioxidant resveratrol-modified cardiac stem cells regenerate infarcted myocardium.
Topics: Animals; Antioxidants; Chemokine CXCL12; Green Fluorescent Proteins; Heart Function Tests; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Regeneration; Resveratrol; Stem Cell Transplantation; Stem Cells; Stilbenes; Wine | 2010 |
Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity.
Topics: Basic Helix-Loop-Helix Transcription Factors; Binding, Competitive; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Gene Expression; Humans; Ligands; Promoter Regions, Genetic; Protective Agents; Protein Binding; Radioligand Assay; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Stilbenes | 2010 |
Procyanidins from apples (Malus pumila Mill.) extend the lifespan of Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cytochromes b; Longevity; Malus; Mutation; Proanthocyanidins; Resveratrol; Sirtuins; Stilbenes; Succinate Dehydrogenase; Temperature | 2011 |
Resveratrol induces apoptosis of human nasopharyngeal carcinoma cells via activation of multiple apoptotic pathways.
Topics: Apoptosis; Carcinoma; Caspases; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Screening Assays, Antitumor; Endoplasmic Reticulum Chaperone BiP; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Models, Biological; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor CHOP | 2011 |
Resveratrol targets transforming growth factor-β2 signaling to block UV-induced tumor progression.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Down-Regulation; Female; Humans; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Mutant Strains; Resveratrol; Signal Transduction; Skin Neoplasms; Stilbenes; Transforming Growth Factor beta2; Tumor Suppressor Protein p53; Ultraviolet Rays | 2011 |
Resveratrol-induced cytotoxicity in human Burkitt's lymphoma cells is coupled to the unfolded protein response.
Topics: Activating Transcription Factor 6; Antineoplastic Agents, Phytogenic; Blotting, Western; Burkitt Lymphoma; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Membrane Glycoproteins; Phosphorylation; Regulatory Factor X Transcription Factors; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Stilbenes; Transcription Factor CHOP; Transcription Factors; Tumor Cells, Cultured; Unfolded Protein Response; Vasodilator Agents; X-Box Binding Protein 1 | 2010 |
Resveratrol-induced p53-independent apoptosis of human nasopharyngeal carcinoma cells is correlated with the downregulation of ΔNp63.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Humans; Nasopharyngeal Neoplasms; Resveratrol; RNA, Small Interfering; Stilbenes; Trans-Activators; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2010 |
Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Combinatorial Chemistry Techniques; Female; Heterocyclic Compounds; Humans; Resveratrol; Stilbenes; Vasodilator Agents | 2010 |
Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.
Topics: Androgen Antagonists; Androgens; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; ErbB Receptors; Formazans; Gene Expression Regulation, Neoplastic; Humans; Male; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Receptors, Androgen; Resveratrol; Signal Transduction; Stilbenes; Tetrazolium Salts; Time Factors | 2010 |
Chronic resveratrol intake reverses pro-inflammatory cytokine profile and oxidative DNA damage in ageing hybrid mice.
Topics: Aging; Animals; Antigens, Surface; Antioxidants; Cell Count; Cytokines; DNA Damage; Inflammation; Mice; Mice, Inbred Strains; Models, Animal; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Resveratrol; Spleen; Stilbenes; T-Lymphocyte Subsets | 2011 |
Resveratrol oligomers from Vatica albiramis.
Topics: Dipterocarpaceae; Fibroblasts; Humans; Interleukin-1beta; Malaysia; Matrix Metalloproteinase 1; Molecular Structure; Phenols; Plant Stems; Plants, Medicinal; Resveratrol; Skin; Stereoisomerism; Stilbenes | 2010 |
Anticancer activity and molecular mechanism of resveratrol-bovine serum albumin nanoparticles on subcutaneously implanted human primary ovarian carcinoma cells in nude mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Cattle; Chromatography, High Pressure Liquid; Cytochromes c; Female; Humans; In Situ Nick-End Labeling; Injections, Subcutaneous; Mice; Mice, Nude; Mitochondria; Nanoparticles; Ovarian Neoplasms; Resveratrol; Serum Albumin, Bovine; Signal Transduction; Stilbenes; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2010 |
Inhibition of TNF-α-mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4'-trimethoxystilbene.
Topics: Cell Adhesion; Cell Line, Tumor; Endothelial Cells; Glucosides; Humans; Intercellular Adhesion Molecule-1; Molecular Structure; Monocytes; NF-kappa B; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2011 |
Resveratrol induces p53 and suppresses myocardin-mediated vascular smooth muscle cell differentiation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Rats; Resveratrol; Serum Response Factor; Signal Transduction; Stilbenes; Trans-Activators; Tumor Suppressor Protein p53 | 2010 |
Resveratrol impairs the release of steroid-resistant inflammatory cytokines from human airway smooth muscle cells in chronic obstructive pulmonary disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Bronchi; Cells, Cultured; Cytokines; Dexamethasone; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-8; Male; Middle Aged; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Respiratory System; Resveratrol; Smoking; Stilbenes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2010 |
Resveratrol protects human lens epithelial cells against H2O2-induced oxidative stress by increasing catalase, SOD-1, and HO-1 expression.
Topics: Apoptosis; Catalase; Cell Line; Cytoprotection; Epithelial Cells; Heme Oxygenase-1; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Lens, Crystalline; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Up-Regulation | 2010 |
Can autophagy promote longevity?
Topics: Aging; Animals; Autophagy; Caenorhabditis elegans; Caloric Restriction; Cellular Senescence; Cytoprotection; Drosophila melanogaster; Humans; Immune System; Immunity; Longevity; Mice; Receptor, IGF Type 1; Resveratrol; Saccharomyces cerevisiae; Sirolimus; Sirtuin 1; Spermidine; Stilbenes; Tumor Suppressor Protein p53 | 2010 |
Stilbene production in cell cultures of Vitis vinifera L. cvs Red Globe and Michele Palieri elicited by methyl jasmonate.
Topics: Acetates; Chromatography, Liquid; Cyclopentanes; Mass Spectrometry; Oxylipins; Resveratrol; Stilbenes; Vitis | 2010 |
Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue.
Topics: Animals; Biocatalysis; Cells, Cultured; Collagen Type IV; Dermis; Female; Fibroblasts; Gene Expression; Gene Expression Regulation, Enzymologic; Humans; Keratinocytes; Matrix Metalloproteinase 9; Metformin; Mice; Mice, Hairless; Resveratrol; Sirtuin 1; Skin; Stilbenes; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2010 |
Dihydro-resveratrol--a potent dietary polyphenol.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dietary Supplements; Female; Flavonoids; Humans; Neoplasms, Hormone-Dependent; Phenols; Polyphenols; Resveratrol; Stilbenes; Wine | 2010 |
Evaluation of the protective effects of quercetin, rutin, naringenin, resveratrol and trolox against idarubicin-induced DNA damage.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chromans; DNA Breaks, Single-Stranded; DNA Damage; Dose-Response Relationship, Drug; Flavanones; Idarubicin; In Vitro Techniques; Mitomycin; NADPH-Ferrihemoprotein Reductase; Quercetin; Rabbits; Resveratrol; Rutin; Stilbenes | 2010 |
Resveratrol protects against methotrexate-induced hepatic injury in rats.
Topics: Alanine Transaminase; Animals; Antimetabolites, Antineoplastic; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Female; Liver; Male; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2010 |
Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cartilage; Chondrocytes; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Immunoprecipitation; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Swine; Transfection | 2010 |
Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.
Topics: Animals; Antioxidants; Bone Marrow; Cell Cycle; Cell Lineage; Colony-Forming Units Assay; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Hematopoietic Stem Cells; Hematopoietic System; Mice; Mice, Knockout; Mice, Transgenic; Resveratrol; Spleen; Stilbenes; Treatment Outcome | 2010 |
Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the advantage of resveratrol in diabetics with acute heart attack is antagonized by insulin.
Topics: Acute Disease; Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Drug Antagonism; Drug Evaluation, Preclinical; Drug Synergism; Heart Failure; Hemodynamics; Hypoglycemic Agents; Insulin; Male; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin; Vasodilator Agents | 2010 |
The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors.
Topics: Animals; Anticarcinogenic Agents; Carbazoles; Cell Differentiation; Cell Proliferation; Cells, Cultured; Epidermis; Isoquinolines; Keratinocytes; Mice; Protein Kinase C; Protein Kinase Inhibitors; Resveratrol; Skin Neoplasms; Stilbenes; Sulfonamides; Tetradecanoylphorbol Acetate | 2010 |
Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillaries; Chronic Disease; Coronary Circulation; Coronary Disease; Disease Models, Animal; Female; Humans; Hypercholesterolemia; Male; Microcirculation; Myocardial Ischemia; Myocardium; Neovascularization, Physiologic; Perfusion; Resveratrol; Signal Transduction; Stilbenes; Swine; Vascular Endothelial Growth Factor A | 2010 |
Effect of resveratrol on gliotransmitter levels and p38 activities in cultured astrocytes.
Topics: Amino Acids; Animals; Astrocytes; Calcium; Cells, Cultured; Chelating Agents; Culture Media; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Mice; Neurotransmitter Agents; p38 Mitogen-Activated Protein Kinases; Resveratrol; Serine; Stilbenes; Stress, Mechanical | 2011 |
Potential of resveratrol analogues as antagonists of osteoclasts and promoters of osteoblasts.
Topics: Animals; Anticarcinogenic Agents; Bone Density Conservation Agents; Cell Line, Tumor; Female; Growth Inhibitors; Humans; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Rats; Resveratrol; Stilbenes; Treatment Outcome | 2010 |
SIRT1 is a novel regulator of key pathways of human labor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Extraembryonic Membranes; Female; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Humans; Labor, Obstetric; Placenta; Pregnancy; Prostaglandins; Resveratrol; RNA; Sirtuin 1; Sirtuin 2; Stilbenes | 2011 |
Resveratrol inhibits development of experimental endometriosis in vivo and reduces endometrial stromal cell invasiveness in vitro.
Topics: Adolescent; Adult; Animals; Endometriosis; Endometrium; Female; Humans; Mice; Mice, Nude; Middle Aged; Resveratrol; Stilbenes; Stromal Cells; Young Adult | 2011 |
Inhibition of aryl hydrocarbon receptor-dependent transcription by resveratrol or kaempferol is independent of estrogen receptor α expression in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Aryl Hydrocarbon Receptor Nuclear Translocator; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Kaempferols; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Stilbenes; Teratogens; Transcription, Genetic | 2010 |
Resveratrol-conjugated poly-ε-caprolactone facilitates in vitro mineralization and in vivo bone regeneration.
Topics: Acrylates; Alkaline Phosphatase; Animals; Bone Regeneration; Calcification, Physiologic; Extracellular Matrix; Hydrolysis; Male; Mesenchymal Stem Cells; Osteogenesis; Polyesters; Porosity; Prosthesis Implantation; Radiography; Rats; Rats, Sprague-Dawley; Resveratrol; Skull; Spectroscopy, Fourier Transform Infrared; Stilbenes; Tissue Scaffolds | 2011 |
Resveratrol and genistein as adenosine triphosphate-depleting agents in fat cells.
Topics: Adenosine Triphosphate; Adipocytes; Alanine; Animals; Biological Transport; Enzyme Inhibitors; Genistein; Insulin; Male; Membrane Potential, Mitochondrial; Mitochondria; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sucrose | 2011 |
Protection against severe intestinal ischemia/reperfusion injury in rats by intravenous resveratrol.
Topics: Animals; Antioxidants; Blood Pressure; Dose-Response Relationship, Drug; Infusions, Intravenous; Intestine, Small; Male; Models, Animal; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Severity of Illness Index; Stilbenes | 2011 |
Resveratrol prevents RANKL-induced osteoclast differentiation of murine osteoclast progenitor RAW 264.7 cells through inhibition of ROS production.
Topics: Animals; Antioxidants; Apoptosis; Carbazoles; Cell Differentiation; Cell Line; Enzyme Activation; Mice; Osteoclasts; RANK Ligand; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2010 |
Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Leucine; Mice; Mice, Knockout; Myoblasts; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Vasodilator Agents | 2010 |
Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.
Topics: AMP-Activated Protein Kinases; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Female; HEK293 Cells; Humans; Lysosomes; Mice; Mice, Inbred C57BL; Molecular Structure; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Transfection | 2011 |
Enhancing melanoma treatment with resveratrol.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Chemotherapy, Adjuvant; Dacarbazine; Disease Models, Animal; Drug Therapy, Combination; Humans; In Vitro Techniques; Melanoma; Melphalan; Mice; Mice, Nude; Mice, SCID; Resveratrol; Skin Neoplasms; Stilbenes; Temozolomide; Treatment Outcome; Xenograft Model Antitumor Assays | 2012 |
Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; Glucose; Glyburide; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Phosphorylation; Quercetin; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats.
Topics: Age Factors; Aging; Animals; Apoptosis; Catalase; Enzyme-Linked Immunosorbent Assay; Hindlimb Suspension; Hydrogen Peroxide; Lipid Peroxidation; Male; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Rats; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2010 |
Preventive oral treatment with resveratrol pro-prodrugs drastically reduce colon inflammation in rodents.
Topics: Acute-Phase Proteins; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Colitis; Colon; Cytokines; Dextran Sulfate; Diarrhea; Dinoprostone; Feces; Gastrointestinal Transit; Glucosides; Humans; Intestinal Absorption; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Peroxidase; Prodrugs; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship | 2010 |
Effect of resveratrol on hemostatic properties of human fibrinogen and plasma during model of hyperhomocysteinemia.
Topics: Adult; Fibrinogen; Homocysteine; Humans; Hyperhomocysteinemia; Resveratrol; Stilbenes | 2010 |
Favorable effects of resveratrol on sympathetic neural remodeling in rats following myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arrhythmias, Cardiac; Biomarkers; Heart Ventricles; Macrophages; Male; Myocardial Infarction; Myocardium; Nerve Growth Factor; Neurons; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Severity of Illness Index; Stilbenes; Sympathetic Nervous System | 2010 |
Resveratrol reduces lipid peroxidation and increases sirtuin 1 expression in adult animals programmed by neonatal protein restriction.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Diet, Protein-Restricted; Female; Insulin; Insulin Resistance; Lipid Peroxidation; Lipids; Liver; Male; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2010 |
Resveratrol upregulated SIRT1, FOXO1, and adiponectin and downregulated PPARγ1-3 mRNA expression in human visceral adipocytes.
Topics: Adipocytes; Adiponectin; Adult; Down-Regulation; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Intra-Abdominal Fat; Lipid Metabolism; Lipid Regulating Agents; Obesity, Morbid; PPAR gamma; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirtuin 1; Stilbenes; Up-Regulation | 2011 |
Role of phenolic compounds in nitric oxide synthase activity in colon and breast adenocarcinoma.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Chemoprevention; Colonic Neoplasms; Female; Humans; Nitric Oxide Synthase; Phenols; Resveratrol; Stilbenes; Tannins | 2010 |
Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Desoxycorticosterone; Fibrosis; Heart; Heart Ventricles; Humans; Hypertension; Male; Mineralocorticoids; Rats; Rats, Wistar; Resveratrol; Sodium Chloride, Dietary; Stilbenes; Ventricular Remodeling | 2011 |
Sensitized synchronous fluorimetric determination of trans-resveratrol and trans-piceid in red wine based on their immobilization on nylon membranes.
Topics: Equipment Design; Glucosides; Indicators and Reagents; Membranes, Artificial; Nylons; Resveratrol; Solutions; Spectrometry, Fluorescence; Stereoisomerism; Stilbenes; Wine | 2010 |
Intracellular GSH depletion triggered mitochondrial Bax translocation to accomplish resveratrol-induced apoptosis in the U937 cell line.
Topics: Apoptosis; bcl-2-Associated X Protein; Glutathione; Humans; Intracellular Fluid; Membrane Potential, Mitochondrial; Mitochondria; Protein Transport; Resveratrol; Stilbenes; U937 Cells | 2011 |
Determination of quercetin and resveratrol in whole blood--implications for bioavailability studies.
Topics: Biological Availability; Chromatography, High Pressure Liquid; Flavonoids; Humans; Methods; Phenols; Polyphenols; Quercetin; Reference Standards; Resveratrol; Stilbenes | 2010 |
Development of a nanoparticle-based FRET sensor for ultrasensitive detection of phytoestrogen compounds.
Topics: Binding Sites; Estrogen Receptor alpha; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Genistein; Humans; Isoflavones; Ligands; Nanoparticles; Phytoestrogens; Resveratrol; Sensitivity and Specificity; Stilbenes | 2010 |
Differential regulation of proliferation, cell cycle control and gene expression in cultured human aortic and pulmonary artery endothelial cells by resveratrol.
Topics: Aorta; Cell Cycle; Cell Proliferation; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Platelet Aggregation Inhibitors; Pulmonary Artery; Resveratrol; Signal Transduction; Stilbenes | 2010 |
Inhibition of 17β-estradiol activation by CYP1A1: genotype- and regioselective inhibition by St. John's Wort and several natural polyphenols.
Topics: Amino Acid Substitution; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Biocatalysis; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Estradiol; Flavonoids; Flavonols; Genotype; Humans; Hydroxylation; Hypericum; Perylene; Phenols; Plant Extracts; Polyphenols; Quercetin; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes; Substrate Specificity | 2011 |
Protective effects of resveratrol against senescence-associated changes in cultured human fibroblasts.
Topics: Blotting, Western; Cell Proliferation; Cells, Cultured; Cellular Senescence; Culture Media; Cytoprotection; DNA; DNA Damage; Fibroblasts; Humans; Resveratrol; Stilbenes | 2011 |
Protective action of resveratrol in human skin: possible involvement of specific receptor binding sites.
Topics: Aged; Apoptosis; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Female; Flavonoids; Humans; Middle Aged; Nitric Oxide Donors; Phenols; Polyphenols; Protective Agents; Protein Binding; Receptors, Cell Surface; Resveratrol; Skin; Stilbenes | 2010 |
Pharmacokinetic study of trans-resveratrol in adult pigs.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Resveratrol; Stilbenes; Swine; Tandem Mass Spectrometry | 2010 |
In vitro BACE-1 inhibitory activity of resveratrol oligomers from the seed extract of Paeonia lactiflora.
Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Baculoviridae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Molecular Structure; Paeonia; Plant Extracts; Resveratrol; Seeds; Stilbenes | 2011 |
Protective, antioxidative and antiapoptotic effects of 2-methoxy-6-acetyl-7-methyljuglone from Polygonum cuspidatum in PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fallopia japonica; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Naphthoquinones; Neuroprotective Agents; PC12 Cells; Phosphorylation; Rats; Resveratrol; Rhizome; Stilbenes; tert-Butylhydroperoxide; Thioctic Acid | 2011 |
Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans.
Topics: Animals; Caenorhabditis elegans; Heterocyclic Compounds, 4 or More Rings; Life Expectancy; Longevity; Resveratrol; Stilbenes | 2010 |
Resveratrol, a phytoestrogen found in red wine, down-regulates protein S expression in HepG2 cells.
Topics: Blood Proteins; Blotting, Western; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Estrogen Receptor alpha; Gene Expression Regulation, Neoplastic; Genistein; Hep G2 Cells; Histocompatibility Antigens; Humans; Liver Neoplasms; Molecular Structure; Phytoestrogens; Promoter Regions, Genetic; Protein C; Protein S; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Structure-Activity Relationship; Time Factors; Transcription, Genetic; Transfection; Wine | 2011 |
Roles and controls of mTOR in the heart. Focus on "mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy".
Topics: Animals; Cardiomegaly; Heart; Myocarditis; Myocytes, Cardiac; Rats; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Triiodothyronine | 2010 |
Anti-angiogenic effects of resveratrol mediated by decreased VEGF and increased TSP1 expression in melanoma-endothelial cell co-culture.
Topics: Angiogenesis Inhibitors; Cell Survival; Cells, Cultured; Coculture Techniques; Drug Evaluation, Preclinical; Endothelial Cells; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Melanoma; Neovascularization, Pathologic; Protein Stability; Resveratrol; Stilbenes; Thrombospondin 1; Vascular Endothelial Growth Factor A | 2010 |
Chemical constituents in the leaves of Vateria indica.
Topics: Circular Dichroism; Dimerization; Dipterocarpaceae; Glucosides; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Leaves; Resveratrol; Stilbenes | 2010 |
Hybrid-increased radical-scavenging activity of resveratrol derivatives by incorporating a chroman moiety of vitamin E.
Topics: Antioxidants; Chromans; Free Radical Scavengers; Molecular Structure; Resveratrol; Stilbenes; Vitamin E | 2010 |
Wine, sirtuins and nephroprotection: not only resveratrol.
Topics: Basic Helix-Loop-Helix Transcription Factors; Electrophoresis; Humans; Kidney Diseases; Kidney Tubules, Proximal; Nitric Oxide; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes; Wine | 2010 |
Resveratrol and N-acetylcysteine block the cancer-initiating step in MCF-10F cells.
Topics: Acetylcysteine; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma; Cell Line; Cell Transformation, Neoplastic; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; Female; Humans; Mammary Glands, Human; Models, Biological; Resveratrol; Stilbenes | 2011 |
Resveratrol confers endothelial protection in insulin-dependent diabetes mellitus: editorial to: "Resveratrol shows vasoprotective effect reducing oxidative stress without affecting metabolic disturbances in insulin-dependent diabetes of rabbits" by F. Ak
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Oxidative Stress; Resveratrol; Stilbenes; Vascular Diseases | 2011 |
[Effects of resveratrol on proliferation and apoptosis of TNF-alpha induced rheumatoid arthritis fibroblast-like synoviocytes].
Topics: Aged; Apoptosis; Arthritis, Rheumatoid; Cell Cycle; Cell Proliferation; Cells, Cultured; Female; Fibroblasts; Humans; Male; Middle Aged; Resveratrol; Stilbenes; Synovial Membrane; Tumor Necrosis Factor-alpha | 2010 |
Resveratrol attenuates oxidized LDL-evoked Lox-1 signaling and consequently protects against apoptotic insults to cerebrovascular endothelial cells.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Survival; Cells, Cultured; Cerebrovascular Circulation; Cytochromes c; Cytoprotection; Down-Regulation; Endothelial Cells; Lipoproteins, LDL; Membrane Potentials; Mice; Mitochondria; Peptide Hydrolases; Reactive Oxygen Species; Receptors, Cell Surface; Resveratrol; RNA, Messenger; RNA, Small Interfering; Scavenger Receptors, Class E; Signal Transduction; Stilbenes; Tissue Distribution | 2011 |
Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes.
Topics: Adipocytes; Adult; Anti-Inflammatory Agents; Female; Gene Expression; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Middle Aged; Phosphorylation; Phytotherapy; Plant Extracts; PPAR gamma; Quercetin; Resveratrol; Signal Transduction; Stilbenes; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitis; Young Adult | 2010 |
Resveratrol arrests cell cycle and induces apoptosis in human hepatocellular carcinoma Huh-7 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Down-Regulation; Humans; Inhibitory Concentration 50; Liver Neoplasms; MAP Kinase Signaling System; Resveratrol; S Phase; Stilbenes; Time Factors; Up-Regulation | 2010 |
Inhibitory effects of resveratrol on the Epstein-Barr virus lytic cycle.
Topics: Animals; Antioxidants; Cell Line; Genes, Immediate-Early; Herpesvirus 4, Human; Humans; Resveratrol; Stilbenes; Transcription, Genetic; Viral Proteins; Virion; Virus Replication | 2010 |
Resveratrol enhances anti-proliferative effect of VACM-1/cul5 in T47D cancer cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Cullin Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Humans; Resveratrol; Stilbenes; Transfection | 2011 |
Resveratrol protects human keratinocytes HaCaT cells from UVA-induced oxidative stress damage by downregulating Keap1 expression.
Topics: Active Transport, Cell Nucleus; Animals; Antioxidants; Cell Line; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Humans; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Keratinocytes; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; RNA, Messenger; Stilbenes; Ultraviolet Rays | 2011 |
ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease.
Topics: Animals; Disease Models, Animal; Drosophila; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flavonols; Gene Dosage; Gene Expression Regulation; Huntingtin Protein; Huntington Disease; JNK Mitogen-Activated Protein Kinases; Mice; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Nuclear Proteins; PC12 Cells; Rats; Resveratrol; Stilbenes; Survival Analysis | 2011 |
Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epoxide Hydrolases; Flavonoids; Hep G2 Cells; Humans; Leukotriene B4; Mice; Mice, Nude; Models, Molecular; Pancreatic Neoplasms; Phenols; Polyphenols; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Resveratrol; RNA Interference; Stilbenes; Time Factors; Wine; Xenograft Model Antitumor Assays | 2010 |
PPARα activation by culinary herbs and spices.
Topics: Apigenin; Chalcones; Dyslipidemias; Humans; Luciferases; Plant Extracts; Plants; Plasmids; PPAR alpha; Resveratrol; Spices; Stilbenes; Transcriptional Activation | 2011 |
Inhibitory effect of epigallocatechin gallate (EGCG), resveratrol, and curcumin on proliferation of human retinal pigment epithelial cells in vitro.
Topics: Antioxidants; Apoptosis; Caspases; Catechin; Cell Division; Cell Proliferation; Cell Survival; Cells, Cultured; Curcumin; Flow Cytometry; Humans; Necrosis; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2010 |
Effects of resveratrol on NO secretion stimulated by insulin and its dependence on SIRT1 in high glucose cultured endothelial cells.
Topics: Antioxidants; E-Selectin; Endothelial Cells; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Nitric Oxide; Nitric Oxide Synthase Type III; Resveratrol; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes; Umbilical Veins | 2010 |
[Research on the virtues of resveratrol].
Topics: Antioxidants; Humans; Neoplasms; Resveratrol; Stilbenes; Wine | 2010 |
Identification and characterization of an inhibitory metal ion-binding site in ferrochelatase.
Topics: Animals; Binding Sites; Buffers; Ferrochelatase; Humans; Hydrogen-Ion Concentration; Inflammation; Ions; Kinetics; Liver; Metals; Mice; Models, Molecular; Mutation; Protein Binding; Protoporphyrins; Resveratrol; Stilbenes | 2010 |
Resveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: role of sirtuin 1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Humans; Naphthols; Neuroblastoma; NF-kappa B; Niacinamide; Proto-Oncogene Proteins c-akt; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Vitamin B Complex | 2011 |
Pan-PPAR agonists based on the resveratrol scaffold: biological evaluation and docking studies.
Topics: Animals; Binding Sites; Cell Line, Tumor; Computer Simulation; Diabetes Mellitus, Experimental; Dietary Fats; Disease Models, Animal; Humans; Mice; Pentanoic Acids; PPAR alpha; PPAR delta; PPAR gamma; Protein Structure, Tertiary; Resveratrol; Stilbenes | 2010 |
Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome.
Topics: Animals; Anticarcinogenic Agents; Disease Models, Animal; Fatty Liver; Hyperglycemia; Hypertriglyceridemia; Inflammation; Insulin Resistance; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Werner Syndrome | 2011 |
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Topics: Aging; Animals; Female; Genetic Heterogeneity; Longevity; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Resveratrol; Simvastatin; Sirolimus; Stilbenes | 2011 |
Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells.
Topics: Animals; Benzamides; Binding Sites; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activators; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Naphthalenes; Naphthols; Promoter Regions, Genetic; Pyrones; Resveratrol; RNA Interference; RNA, Messenger; Sirtuin 1; Stilbenes; Thromboplastin; Thrombosis; Transcription Factor RelA; Transfection | 2011 |
Resveratrol recruits rat muscle microvasculature via a nitric oxide-dependent mechanism that is blocked by TNFα.
Topics: Animals; Antioxidants; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Male; Microvessels; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Vasodilator Agents | 2011 |
Polydatin ameliorates DSS-induced colitis in mice through inhibition of nuclear factor-kappaB activation.
Topics: Animals; Anti-Inflammatory Agents; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Glucosides; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Pilot Projects; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; AMP-Activated Protein Kinases; Animals; Forkhead Box Protein O1; Forkhead Transcription Factors; Glutathione Transferase; Mice; Protein Multimerization; Protein Serine-Threonine Kinases; Protein Structure, Quaternary; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Stilbenes; Up-Regulation | 2011 |
Resveratrol protects against oxidized LDL-induced breakage of the blood-brain barrier by lessening disruption of tight junctions and apoptotic insults to mouse cerebrovascular endothelial cells.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Endothelium, Vascular; Lipoproteins, LDL; Mice; Resveratrol; Stilbenes; Tight Junctions | 2010 |
Comparative antioxidant activities and synergism of resveratrol and oxyresveratrol.
Topics: Antioxidants; Artocarpus; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Curcumin; Drug Synergism; Molecular Structure; Oxidation-Reduction; Plant Extracts; Resveratrol; Stilbenes; Tetramethylphenylenediamine | 2010 |
Resveratrol represses YKL-40 expression in human glioma U87 cells.
Topics: Adipokines; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitinase-3-Like Protein 1; Culture Media; Disease-Free Survival; Gene Expression Regulation, Neoplastic; Glioma; Glycoproteins; Humans; Lectins; Prognosis; Promoter Regions, Genetic; Recurrence; Resveratrol; Stilbenes | 2010 |
Antiproliferative effect of resveratrol in pancreatic cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Humans; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; X-Linked Inhibitor of Apoptosis Protein | 2010 |
Histological assessment of SJL/J mice treated with the antioxidants coenzyme Q10 and resveratrol.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Mice; Muscle, Skeletal; Muscular Dystrophies; Resveratrol; Stilbenes; Ubiquinone | 2011 |
[Electrophysiological effects of resveratrol on autorhythmicity organization in left ventricular outflow tract of guinea pig].
Topics: Animals; Guinea Pigs; Heart Ventricles; Male; Resveratrol; Stilbenes | 2010 |
[Effects of resveratrol on immunity function of mice performing endurance exercise].
Topics: Animals; Cell Proliferation; Lymphocyte Count; Male; Mice; Physical Endurance; Resveratrol; Stilbenes; T-Lymphocyte Subsets | 2010 |
Electron spin resonance and luminescence spectroscopic observation and kinetic study of chemical and physical singlet oxygen quenching by resveratrol in methanol.
Topics: Electron Spin Resonance Spectroscopy; Kinetics; Methanol; Resveratrol; Singlet Oxygen; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared; Stilbenes | 2010 |
Control of prostate cell growth, DNA damage and repair and gene expression by resveratrol analogues, in vitro.
Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle; Cell Line, Tumor; DNA Damage; DNA Repair; Gene Expression; Humans; Male; Prostatic Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Efficient synthesis of natural polyphenolic stilbenes: resveratrol, piceatannol and oxyresveratrol.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Fallopia japonica; Flavonoids; Molecular Structure; Moraceae; Phenols; Plant Extracts; Plants; Polyphenols; Protein-Tyrosine Kinases; Resveratrol; Stilbenes | 2010 |
The combination of bortezomib and resveratrol may prevent muscle wasting in diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Boronic Acids; Bortezomib; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Inflammation; Models, Biological; Muscular Atrophy; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Rats; Resveratrol; Stilbenes | 2011 |
Reduction of blood cholesterol and ischemic injury in the hypercholesteromic rabbits with modified resveratrol, longevinex. [corrected]
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Biomarkers; Cholesterol; Disease Models, Animal; Down-Regulation; Hemodynamics; Hypercholesterolemia; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rabbits; Resveratrol; Stilbenes; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
Resveratrol improves cardiovascular function and reduces oxidative organ damage in the renal, cardiovascular and cerebral tissues of two-kidney, one-clip hypertensive rats.
Topics: Animals; Antioxidants; Brain; Cardiovascular Physiological Phenomena; Catalase; Glutathione; Heart; Kidney; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2010 |
Specific poly-phenolic compounds in cell culture of Vitis vinifera L. cv. Gamay Fréaux.
Topics: Anthocyanins; Cell Culture Techniques; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonoids; Magnetic Resonance Spectroscopy; Phenols; Polyphenols; Resveratrol; Signal Transduction; Stilbenes; Vitis | 2011 |
Vitamin C, resveratrol and lipoic acid actions on isolated rat liver mitochondria: all antioxidants but different.
Topics: Animals; Antioxidants; Ascorbic Acid; Glutathione Peroxidase; Hydrogen Peroxide; Male; Mitochondria, Liver; Oxidants; Oxidative Stress; Oxygen Consumption; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxides; Thioctic Acid | 2010 |
Spontaneous mutagenesis in Csb(m/m)Ogg1⁻(/)⁻ mice is attenuated by dietary resveratrol.
Topics: Animals; Antimutagenic Agents; Diet; DNA Damage; Gene Expression; Liver; Mice; Mice, Transgenic; Mutagenesis; Oxidative Stress; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Analysis of polyphenols using capillary zone electrophoresis--determination of the most effective wine sample pre-treatment method.
Topics: Borates; Chemical Fractionation; Electrophoresis, Capillary; Flavonoids; Hydrogen-Ion Concentration; Linear Models; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Temperature; Wine | 2010 |
Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner.
Topics: Analysis of Variance; Angiotensin II; Animals; Antioxidants; Cell Shape; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Hydrogen Peroxide; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Oxidation-Reduction; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Time Factors; Transfection | 2011 |
Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection.
Topics: Animals; Antioxidants; Blotting, Western; Cell Line; Cell Survival; Heme Oxygenase-1; Hippocampus; Immunoprecipitation; In Vitro Techniques; Melatonin; Mice; Neuroprotective Agents; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Ubiquitin | 2011 |
Inhibitory mechanisms of the transcriptional activity of androgen receptor by resveratrol: Implication of DNA binding and acetylation of the receptor.
Topics: Acetylation; Antineoplastic Agents, Phytogenic; Binding Sites; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA; Humans; Microscopy, Fluorescence; Prostate-Specific Antigen; Receptors, Androgen; Resveratrol; Stilbenes; Transcriptional Activation | 2011 |
Cleavage of resveratrol in fungi: characterization of the enzyme Rco1 from Ustilago maydis.
Topics: Carotenoids; Gene Deletion; Gene Expression; Oxygenases; Phylogeny; Recombinant Proteins; Resveratrol; Sequence Homology, Amino Acid; Stilbenes; Substrate Specificity; Ustilago | 2011 |
SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death.
Topics: Animals; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; HEK293 Cells; Histone Deacetylases; Humans; Mice; Neurons; Peptide Fragments; Prions; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action.
Topics: Animals; Autophagy; Cardiotonic Agents; Forkhead Transcription Factors; Heart; In Vitro Techniques; Male; Myocardial Infarction; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Ventricular Function, Left | 2010 |
Role of resveratrol in FOXO1-mediated gluconeogenic gene expression in the liver.
Topics: Animals; Antioxidants; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Gluconeogenesis; Humans; Liver; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Up-Regulation | 2010 |
FoxO1 regulates muscle fiber-type specification and inhibits calcineurin signaling during C2C12 myoblast differentiation.
Topics: Animals; Calcineurin; Cell Differentiation; Cell Line; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Glycolysis; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Myoblasts, Skeletal; Myosin Heavy Chains; Oxidation-Reduction; Phenotype; Phosphoric Monoester Hydrolases; Physical Endurance; Resveratrol; Signal Transduction; Stilbenes; Swimming; Transfection | 2011 |
Evidence for ectopic aerobic ATP production on C6 glioma cell plasma membrane.
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cell Respiration; Electron Transport Complex IV; Glioma; Nigericin; Oxidation-Reduction; Oximetry; Protein Transport; Proton-Translocating ATPases; Rats; Resveratrol; Spectrophotometry; Stilbenes; Subcellular Fractions; Wheat Germ Agglutinins | 2011 |
Neuroprotective effects of resveratrol derivatives from the roots of Vitis thunbergii var. sinuate against glutamate-induced neurotoxicity in primary cultured rat cortical cells.
Topics: Animals; Cell Culture Techniques; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromatography, Thin Layer; Glutamic Acid; Molecular Structure; Neuroglia; Neurons; Neuroprotective Agents; Plant Roots; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitis | 2011 |
Protective effect of resveratrol and vitamin E against ethanol-induced oxidative damage in mice: biochemical and immunological basis.
Topics: Animals; Antioxidants; Cytokines; Enzymes; Ethanol; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Vitamin E | 2010 |
[Effect and underlying mechanism of resveratol on porcine primary preadipocyte apoptosis].
Topics: Adipocytes; Adipogenesis; Animals; Antioxidants; Apoptosis; Caspase 3; Cells, Cultured; Resveratrol; Sirtuin 1; Stilbenes; Swine | 2010 |
Effect of resveratrol and quercetin in experimental infection by Salmonella enterica serovar Typhimurium.
Topics: Antioxidants; Apoptosis; Cell Culture Techniques; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; fas Receptor; Humans; In Situ Nick-End Labeling; Leukocytes, Mononuclear; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Quercetin; Resveratrol; Salmonella typhimurium; Stilbenes; U937 Cells | 2011 |
Resveratrol reduces oxidative stress and cell death and increases mitochondrial antioxidants and XIAP in PC6.3-cells.
Topics: Antioxidants; Apoptosis; Blotting, Western; Cell Line; Humans; Mitochondria; Mitochondrial Proteins; Neurons; Oxidative Stress; Polymerase Chain Reaction; Resveratrol; Stilbenes; Superoxide Dismutase; Thioredoxins; X-Linked Inhibitor of Apoptosis Protein | 2011 |
[Mechanisms of resveratrol bovine serum albumin nanoparticle-induced cell death in human ovarian cancer SKOV3 cells].
Topics: Apoptosis; Caspase 3; Caspase 9; Cell Death; Cell Line, Tumor; Cytochromes c; Female; Humans; Nanoparticles; Ovarian Neoplasms; Resveratrol; Stilbenes | 2010 |
Effects of various agents on DNA fragmentation and telomerase enzyme activities in adenocarcinoma cell lines.
Topics: Adenocarcinoma; Analysis of Variance; Cell Line, Tumor; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Humans; Quercetin; Resveratrol; Stilbenes; Tamoxifen; Tannins; Telomerase | 2011 |
I've heard a lot about resveratrol lately, and understand it's found in wine, primarily red. What are the benefits of resveratrol, and if I'm not a wine drinker, are there other sources of it?
Topics: Antioxidants; Arachis; Blueberry Plants; Humans; Resveratrol; Stilbenes; Vaccinium macrocarpon; Vitis; Wine | 2010 |
Preserving and restoring optic nerve function.
Topics: Animals; Cell Survival; Encephalomyelitis, Autoimmune, Experimental; Female; Humans; Multiple Sclerosis; Nerve Degeneration; Nerve Regeneration; Optic Nerve; Optic Nerve Diseases; Resveratrol; Retinal Ganglion Cells; Stilbenes | 2010 |
Oral resveratrol reduces neuronal damage in a model of multiple sclerosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Mice; Multiple Sclerosis; Nerve Degeneration; Resveratrol; Stilbenes | 2010 |
Resveratrol enhances fatty acid oxidation capacity and reduces resistin and Retinol-Binding Protein 4 expression in white adipocytes.
Topics: 3T3-L1 Cells; Adipocytes, White; Adipokines; Animals; Antioxidants; Fatty Acids; Glucose Transporter Type 4; Mice; Oxidation-Reduction; PPAR gamma; Resistin; Resveratrol; Retinol-Binding Proteins, Plasma; RNA, Messenger; Stilbenes; Triglycerides | 2011 |
Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury.
Topics: Animals; Disease Models, Animal; Motor Activity; Neurons; Neuroprotective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Resveratrol; Spinal Cord Injuries; Stilbenes | 2011 |
Effects of combined treatment with resveratrol and indole-3-carbinol.
Topics: Analysis of Variance; Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dietary Supplements; DNA Primers; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Glutathione Transferase; Indoles; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Steroid Hydroxylases; Stilbenes | 2010 |
Anti-angiogenic effect of resveratrol or curcumin in Ehrlich ascites carcinoma-bearing mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Curcumin; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Resveratrol; Stilbenes; Time Factors; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Cardiotonic Agents; Cells, Cultured; Energy Metabolism; Fatty Acids; Gene Expression; Lipid Metabolism; Mice; Mice, Mutant Strains; Myocarditis; Myocytes, Cardiac; NF-kappa B; Oxidation-Reduction; PPAR alpha; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
Resveratrol: an assessment of its dose response an introduction.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance' by Calabrese et al.
Topics: Animals; Biomedical Research; Cardiotonic Agents; Cardiovascular System; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes; Wine | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance'.
Topics: Animals; Biomedical Research; Dose-Response Relationship, Drug; Ethanol; Humans; Receptors, Calcitriol; Resveratrol; Stilbenes; Vitamin D | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance' by Calabrese et al.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance'.
Topics: Animals; Biological Availability; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Commentary on resveratrol and hormesis: resveratrol--a hormetic marvel in waiting?
Topics: Animals; Biological Availability; Biomedical Research; Dose-Response Relationship, Drug; Humans; Nonprescription Drugs; Resveratrol; Solubility; Stilbenes | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance'.
Topics: Animals; Biomedical Research; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Commentary on 'resveratrol commonly displays hormesis: occurrence and biomedical significance'.
Topics: Animals; Biomedical Research; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Dose response biology: the case of resveratrol.
Topics: Animals; Biomedical Research; Dose-Response Relationship, Drug; Humans; Resveratrol; Stilbenes | 2010 |
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats.
Topics: Administration, Oral; Animals; Antioxidants; Area Under Curve; Biological Availability; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Half-Life; Injections, Intravenous; Male; Rats; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2011 |
Dose-dependent antioxidant function of resveratrol demonstrated via modulation of reactive oxygen species in normal human skin fibroblasts in vitro.
Topics: Antineoplastic Agents; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fibroblasts; Free Radicals; Humans; Hydrogen Peroxide; Lipid Peroxidation; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Skin; Stilbenes; Up-Regulation | 2010 |
Effect of trans-resveratrol on induced oxidative stress in human sperm and in rat germinal cells.
Topics: Animals; Antioxidants; Cell Survival; Humans; Lethal Dose 50; Lipid Peroxidation; Male; Microscopy, Electron, Transmission; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Spermatids; Spermatocytes; Spermatozoa; Stilbenes; tert-Butylhydroperoxide; Testis | 2011 |
Resveratrol protects against a model of vacuous chewing movements induced by reserpine in mice.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dyskinesia, Drug-Induced; Mastication; Mice; Motor Activity; Reserpine; Resveratrol; Stilbenes | 2011 |
Investigation of piceid metabolites in rat by liquid chromatography tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Fermentation; Glucosides; Intestines; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2011 |
Bioconversion of grape and chokeberry wine polyphenols during simulated gastrointestinal in vitro digestion.
Topics: Antioxidants; Bacteria; Caffeic Acids; Chlorogenic Acid; Feces; Flavonoids; Gastrointestinal Tract; Humans; Models, Biological; Phenols; Photinia; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Vitis; Wine | 2011 |
Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Doxorubicin; Ileum; Immunohistochemistry; Kidney; Liver; Male; Microscopy, Electron, Transmission; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
A novel multicommuted fluorimetric optosensor for determination of resveratrol in beer.
Topics: Beer; Chemistry Techniques, Analytical; Flow Injection Analysis; Fluorometry; Food Analysis; Hydrogen-Ion Concentration; Resveratrol; Solid Phase Extraction; Stilbenes; Time Factors | 2011 |
The molecular basis of distinct aggregation pathways of islet amyloid polypeptide.
Topics: Amyloid; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Microscopy, Atomic Force; Nuclear Magnetic Resonance, Biomolecular; Protein Multimerization; Resveratrol; Stilbenes | 2011 |
FoxO1 mediates an autofeedback loop regulating SIRT1 expression.
Topics: Animals; Enzyme Inhibitors; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Nerve Tissue Proteins; Rats; Response Elements; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Transcription, Genetic | 2011 |
Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileitis; Inflammation; Intestine, Small; Mice; Mice, Inbred C57BL; Resveratrol; Simvastatin; Stilbenes; Th1 Cells; Toxoplasma | 2010 |
Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzamides; Captopril; Catechin; Cell Differentiation; Cell Line; Cell Proliferation; Dioxoles; Dose-Response Relationship, Drug; Mice; Muscle Development; Myoblasts; Receptors, Transforming Growth Factor beta; Resveratrol; Signal Transduction; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1; Tretinoin; Vitamin D; Vitamins | 2010 |
[Effects of resveratrol on the proliferation and CaN of vascular smooth muscle cell induced by angiotensin II].
Topics: Angiotensin II; Animals; Calcineurin; Calmodulin; Cell Proliferation; Cells, Cultured; Female; Muscle, Smooth, Vascular; Rabbits; Random Allocation; Resveratrol; Stilbenes | 2009 |
Multiwalled carbon nanotubes as sorbent for online solid-phase extraction of resveratrol in red wines prior to fused-core C18-based ultrahigh-performance liquid chromatography-tandem mass spectrometry quantification.
Topics: Chromatography, High Pressure Liquid; Isomerism; Nanotubes, Carbon; Plant Extracts; Resveratrol; Solid Phase Extraction; Stilbenes; Tandem Mass Spectrometry; Wine | 2011 |
Inhibition of NF-κB signaling commits resveratrol-treated medulloblastoma cells to apoptosis without neuronal differentiation.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cerebellum; Flow Cytometry; Humans; Lipopolysaccharides; Medulloblastoma; Neurons; NF-kappa B; Proline; Protein Array Analysis; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tetrazolium Salts; Thiazoles; Thiocarbamates; Time Factors | 2011 |
Two new resveratrol tetramers isolated from Cayratia japonica (Thunb.) Gagn. with strong inhibitory activity on fatty acid synthase and antioxidant activity.
Topics: Antioxidants; Fatty Acid Synthases; Indenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Resorcinols; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Vitaceae | 2010 |
Resveratrol for a longer life--if you're a yeast. The cardiovascular promise of this red wine compound has not been confirmed in humans.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Cardiovascular System; Health Knowledge, Attitudes, Practice; Humans; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2010 |
Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.
Topics: Animals; Carbazoles; Cell Line, Tumor; DNA-Binding Proteins; Enzyme Inhibitors; Glucokinase; Glucose; Glucose Transporter Type 2; Hepatocyte Nuclear Factor 1; High Mobility Group Proteins; Homeodomain Proteins; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitochondria; Mitochondrial Proteins; Oxygen Consumption; Rats; Resveratrol; Sirtuin 1; Stilbenes; Trans-Activators; Transcription Factors; Up-Regulation | 2011 |
Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Immunoblotting; Inhibitory Concentration 50; Membrane Proteins; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases | 2011 |
Preparation and evaluation of zinc-pectin-chitosan composite particles for drug delivery to the colon: role of chitosan in modifying in vitro and in vivo drug release.
Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Colon; Cross-Linking Reagents; Drug Carriers; Drug Stability; Drug Storage; Male; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Pectins; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes; Surface Properties; Tissue Distribution; Zinc Acetate | 2011 |
Resveratrol induces growth arrest and apoptosis through activation of FOXO transcription factors in prostate cancer cells.
Topics: Androstadienes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromones; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Male; Morpholines; Mutation; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Wortmannin | 2010 |
Resveratrol induces Notch2-mediated apoptosis and suppression of neuroendocrine markers in medullary thyroid cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Carcinoma, Medullary; Caspase 3; Cell Line, Tumor; Cell Proliferation; Chromogranin A; Humans; Neurosecretory Systems; Poly(ADP-ribose) Polymerases; Receptor, Notch2; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Thyroid Neoplasms | 2011 |
Inducible COX-2-dependent apoptosis in human ovarian cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclooxygenase 2; Female; Humans; Microscopy, Confocal; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Protein Transport; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; SUMO-1 Protein; Transfection; Tumor Suppressor Protein p53 | 2011 |
Molecular targets of the natural antioxidant pterostilbene: effect on protein kinase C, caspase-3 and apoptosis in human neutrophils in vitro.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Survival; Computer Simulation; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Neutrophils; Phosphorylation; Protein Kinase C; Resveratrol; Stilbenes | 2010 |
Formation of reactive oxygen and nitrogen species in the presence of pinosylvin - an analogue of resveratrol.
Topics: Animals; Antioxidants; Antirheumatic Agents; Arthritis, Experimental; Cell Line; Disease Models, Animal; Drug Therapy, Combination; Macrophages; Male; Methotrexate; Neutrophils; Nitric Oxide; Rats; Rats, Inbred Lew; Reactive Oxygen Species; Resveratrol; Stilbenes | 2010 |
Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Proliferation; Cell Survival; Death-Associated Protein Kinases; Fatty Acid Synthases; Female; Gene Expression; Gene Knockdown Techniques; Humans; Lipogenesis; Membrane Proteins; Mice; Mice, Nude; Neoplastic Stem Cells; Proto-Oncogene Proteins; Resveratrol; RNA Interference; Stilbenes; Xenograft Model Antitumor Assays | 2011 |
Resveratrol down-regulates interferon-γ-inducible inflammatory genes in macrophages: molecular mechanism via decreased STAT-1 activation.
Topics: Animals; Chemokine CXCL10; Down-Regulation; Humans; Interferon-gamma; Janus Kinase 2; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Resveratrol; RNA, Messenger; STAT1 Transcription Factor; Stilbenes; Transcription, Genetic | 2011 |
Effects of pulsed electric field on secondary metabolism of Vitis vinifera L. cv. Gamay Fréaux suspension culture and exudates.
Topics: Anthocyanins; Cell Culture Techniques; Chromatography, High Pressure Liquid; Electromagnetic Fields; Energy Metabolism; Hydroxybenzoates; Plant Proteins; Plants; Resveratrol; Stilbenes; Suspensions; Vitis | 2011 |
Role of Na+/H+ exchanger in resveratrol-induced growth inhibition of human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cation Transport Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Resveratrol; Sodium-Hydrogen Exchanger 1; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Stilbenes | 2012 |
Role of estrogen receptor-dependent upregulation of P38 MAPK/heme oxygenase 1 in resveratrol-mediated attenuation of intestinal injury after trauma-hemorrhage.
Topics: Animals; Chemokine CXCL1; Chemokine CXCL2; Heme Oxygenase-1; Intercellular Adhesion Molecule-1; Interleukin-6; Intestinal Mucosa; Intestines; Male; p38 Mitogen-Activated Protein Kinases; Peroxidase; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Resveratrol; Shock, Hemorrhagic; Stilbenes; Tumor Necrosis Factor-alpha; Wounds and Injuries | 2011 |
Determination of resveratrol and piceid in beer matrices by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Beer; Chromatography, Liquid; Glucosides; Least-Squares Analysis; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Solid Phase Extraction; Stereoisomerism; Stilbenes; Tandem Mass Spectrometry | 2011 |
Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2.
Topics: Antioxidants; Aryldialkylphosphatase; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Interactions; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Hepatocytes; Humans; Hydrogen Peroxide; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; RNA, Messenger; Stilbenes; Transcriptional Activation | 2011 |
Restoration of altered microRNA expression in the ischemic heart with resveratrol.
Topics: Animals; Cardiotonic Agents; Computational Biology; Heart; Male; Mice; MicroRNAs; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Software; Stilbenes | 2010 |
The effect of resveratrol on the Werner syndrome RecQ helicase gene and telomerase activity.
Topics: Antioxidants; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Exodeoxyribonucleases; Female; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Promoter Regions, Genetic; RecQ Helicases; Resveratrol; Stilbenes; Telomerase; Up-Regulation; Uterine Cervical Neoplasms; Werner Syndrome Helicase | 2011 |
Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3.
Topics: Activating Transcription Factor 3; Anticarcinogenic Agents; Apoptosis; Base Sequence; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Colorectal Neoplasms; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Luciferases; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Transcriptional Activation | 2011 |
Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway.
Topics: Aged; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Genistein; Hep G2 Cells; Hepatocytes; Humans; Male; Middle Aged; Resveratrol; Ribonucleosides; Signal Transduction; Stilbenes | 2011 |
In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds.
Topics: Analysis of Variance; Anticarcinogenic Agents; Apoptosis; Butyrates; Caco-2 Cells; Catechin; Cell Differentiation; Cell Proliferation; Cell Survival; Flavonoids; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Regression Analysis; Resveratrol; Rutin; Stilbenes | 2011 |
Anti-angiogenic effects of resveratrol on cerebral angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Cattle; Cell Line; Cells, Cultured; Cerebral Arteries; Endothelial Cells; Humans; Neovascularization, Pathologic; Resveratrol; Stilbenes | 2011 |
Sugar levels in Charmat sparkling wines can affect the quality and resveratrol levels.
Topics: Antioxidants; beta-Glucosidase; Biphenyl Compounds; Catalase; Flavonoids; Phenols; Picrates; Polyphenols; Resveratrol; Stilbenes; Superoxide Dismutase; Wine | 2010 |
Resveratrol prevents oxidative stress and inhibition of Na(+)K(+)-ATPase activity induced by transient global cerebral ischemia in rats.
Topics: Animals; Antioxidants; Hippocampus; Ischemic Attack, Transient; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes; Thiobarbituric Acid Reactive Substances | 2011 |
Resveratrol enhances antitumor activity of TRAIL in prostate cancer xenografts through activation of FOXO transcription factor.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Flavonoids; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Ki-67 Antigen; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Phenols; Polyphenols; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand | 2010 |
Inhibitory effects of resveratrol on platelet activation induced by thromboxane a(2) receptor agonist in human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Dose-Response Relationship, Drug; Fibrinogen; Humans; Plant Extracts; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Receptors, Thromboxane A2, Prostaglandin H2; Resveratrol; Stilbenes; Vasoconstrictor Agents; Vitis; Young Adult | 2011 |
Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase.
Topics: Animals; Antioxidants; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Fulvestrant; Gene Expression; Humans; Hydrogen Peroxide; Mice; Mitochondria; Neoplasms; Nitriles; Phenols; Propionates; Pyrazoles; Resveratrol; Stilbenes; Stress, Physiological; Superoxide Dismutase; Up-Regulation | 2011 |
Effect of oral resveratrol on the BDNF gene expression in the hippocampus of the rat brain.
Topics: Administration, Oral; Animals; Antioxidants; Base Sequence; Brain-Derived Neurotrophic Factor; DNA Primers; Gene Expression; Hippocampus; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.
Topics: Animals; Cells, Cultured; Energy Metabolism; Fibroblasts; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; Neuronal Ceroid-Lipofuscinoses; Oxidative Stress; Phosphorylation; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Ribosomes; Stilbenes; Thiolester Hydrolases; Up-Regulation | 2011 |
Molecular structure-affinity relationship of natural polyphenols for bovine γ-globulin.
Topics: Animals; Catechin; Cattle; Flavonoids; gamma-Globulins; Glycosylation; Hydrogenation; Hydroxylation; Molecular Structure; Phenols; Polyphenols; Protein Binding; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Structure-Activity Relationship | 2011 |
Regulation of p53 and cell proliferation by resveratrol and its derivatives in breast cancer cells: an in silico and biochemical approach targeting integrin αvβ3.
Topics: Anticarcinogenic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Estrogen Receptor alpha; Female; Flow Cytometry; Humans; Integrin alphaVbeta3; Mitogen-Activated Protein Kinases; Oligopeptides; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2011 |
Structure of trans-resveratrol in complex with the cardiac regulatory protein troponin C.
Topics: Cardiotonic Agents; Deuterium Oxide; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Models, Molecular; Myocardium; Protein Binding; Protein Conformation; Resveratrol; Stilbenes; Troponin C | 2011 |
Piceatannol is more effective than resveratrol in restoring endothelial cell dimethylarginine dimethylaminohydrolase expression and activity after high-glucose oxidative stress.
Topics: Amidohydrolases; Animals; Antioxidants; Aorta; Arginase; Arginine; Blotting, Western; Cattle; Cell Line; Endothelial Cells; Glucose; Hyperglycemia; Immunoprecipitation; Naphthalenes; Nitric Oxide Synthase; Oxidative Stress; Pyrones; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
Resveratrol with antioxidant activity inhibits matrix metalloproteinase via modulation of SIRT1 in human fibrosarcoma cells.
Topics: Antioxidants; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Damage; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Lipid Peroxidation; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; NF-kappa B; Oxidation-Reduction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes; Transcription Factor AP-1 | 2011 |
Resveratrol-mediated SIRT-1 interactions with p300 modulate receptor activator of NF-kappaB ligand (RANKL) activation of NF-kappaB signaling and inhibit osteoclastogenesis in bone-derived cells.
Topics: Animals; Bone Marrow Cells; Cell Line; Core Binding Factor Alpha 1 Subunit; Dogs; Enzyme Inhibitors; Humans; Mice; Multiprotein Complexes; NF-kappa B; Osteoclasts; Osteoporosis; p300-CBP Transcription Factors; RANK Ligand; Resveratrol; Rheumatic Fever; Signal Transduction; Sirtuin 1; Stilbenes; Up-Regulation | 2011 |
Cyclodextrin-based nanosponges for delivery of resveratrol: in vitro characterisation, stability, cytotoxicity and permeation study.
Topics: Administration, Buccal; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cell Line, Tumor; Cell Proliferation; Cellulose; Cyclodextrins; Drug Carriers; Drug Compounding; Drug Stability; Excipients; Humans; In Vitro Techniques; Nanostructures; Particle Size; Permeability; Rabbits; Resveratrol; Solubility; Stilbenes | 2011 |
Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1.
Topics: Adult; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Case-Control Studies; Cell Line; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Longevity; Middle Aged; Muscle Fibers, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Recombinant Fusion Proteins; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol modulates the expression of PTGS2 and cellular proliferation in the normal rat endometrium in an AKT-dependent manner.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endometrium; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Organ Size; Phosphorylation; Phytoestrogens; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Resveratrol; Stilbenes; Uterus; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Resveratrol prevents embryonic oxidative stress and apoptosis associated with diabetic embryopathy and improves glucose and lipid profile of diabetic dam.
Topics: Animals; Apoptosis; Blood Glucose; Caspases; Embryonic Development; Enzyme Activation; Female; Fetal Diseases; Glutathione; Lipid Peroxidation; Lipids; Male; Oxidative Stress; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2011 |
A study of resveratrol-copper complexes by electrospray ionization mass spectrometry and density functional theory calculations.
Topics: Copper; Copper Sulfate; Models, Chemical; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Thermodynamics | 2011 |
Resveratrol inhibits transforming growth factor-β-induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration.
Topics: Actins; Cell Differentiation; Cell Line; Cell Proliferation; Collagen; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression; Humans; Lung; Myofibroblasts; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pulmonary Fibrosis; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Transforming Growth Factor beta | 2011 |
Vardenafil and resveratrol synergistically enhance the nitric oxide/cyclic guanosine monophosphate pathway in corpus cavernosal smooth muscle cells and its therapeutic potential for erectile dysfunction in the streptozotocin-induced diabetic rat: prelimin
Topics: Animals; Antioxidants; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Imidazoles; Male; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase Type III; Penis; Phosphodiesterase 5 Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfones; Triazines; Vardenafil Dihydrochloride | 2011 |
Resveratrol improves oxidative stress and protects against diabetic nephropathy through normalization of Mn-SOD dysfunction in AMPK/SIRT1-independent pathway.
Topics: AMP-Activated Protein Kinases; Animals; Blood Glucose; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Immunohistochemistry; Immunoprecipitation; Kidney; Male; Mice; Oxidative Stress; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2011 |
Resveratrol as an adjunct therapy in cyclophosphamide-treated MCF-7 cells and breast tumor explants.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Chemotherapy, Adjuvant; Cyclophosphamide; Female; Humans; Immunoprecipitation; Microscopy, Electron, Transmission; Middle Aged; Oxidative Stress; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2011 |
Effects of resveratrol on ileal smooth muscle reactivity in polymicrobial sepsis model.
Topics: Animals; Antioxidants; Cecum; Ileum; Interleukin-1; Ligation; Male; Muscle, Smooth; Rats; Rats, Wistar; Resveratrol; Sepsis; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
GADD45α and annexin A1 are involved in the apoptosis of HL-60 induced by resveratrol.
Topics: Annexin A1; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Growth Processes; Cell Survival; DNA Damage; G1 Phase; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Resting Phase, Cell Cycle; Resveratrol; Stilbenes | 2011 |
Silent information regulator 1 mediates hippocampal plasticity through presenilin1.
Topics: Animals; Antioxidants; Blotting, Western; Chromatin Immunoprecipitation; Gene Expression; Gene Expression Regulation; HEK293 Cells; Hippocampus; Humans; Immunohistochemistry; Male; Neuronal Plasticity; Presenilin-1; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes | 2011 |
Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53.
Topics: Acetylation; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Body Weight; Cytochromes c; Doxorubicin; Gene Expression; Male; Mice; Mice, Inbred BALB C; Myocardium; Myocytes, Cardiac; Organ Size; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Ventricular Dysfunction, Left | 2011 |
Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes.
Topics: Antioxidants; Cell Survival; Cells, Cultured; DNA Damage; DNA Repair; Ethanol; Female; Humans; Hydroxyl Radical; Lymphocytes; Male; Oxidation-Reduction; Resveratrol; Stilbenes | 2011 |
Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice.
Topics: Administration, Oral; Angiogenesis Inhibitors; Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Endothelium, Vascular; Female; Fluorescent Antibody Technique, Indirect; Glial Fibrillary Acidic Protein; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Receptors, LDL; Resveratrol; Retina; Retinal Neovascularization; Retinal Telangiectasis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A | 2011 |
Protective effect of resveratrol on acute lung injury induced by lipopolysaccharide in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Chemokine CCL3; Disease Models, Animal; Interleukin-1beta; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2011 |
Inhibitory effect of (E)-1,2-di(3,5-dimethoxyphenyl)ethene on 3T3-L1 adiopocyte differentiation.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Adipocytes; Animals; Cell Differentiation; Fatty Acid Synthases; Fatty Acids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2010 |
A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal.
Topics: Adult; Antioxidants; Blotting, Western; Cytokines; Dietary Carbohydrates; Dietary Fats; DNA; Fallopia japonica; Female; Flavonoids; Humans; Inflammation; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; NF-E2-Related Factor 2; Oxidative Stress; Phenols; Plant Extracts; Polyphenols; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Toll-Like Receptor 4; Vitis | 2011 |
Fluorinated N,N-dialkylaminostilbenes for Wnt pathway inhibition and colon cancer repression.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Resveratrol; Signal Transduction; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Transplantation, Heterologous; Wnt Proteins | 2011 |
Resveratrol improves cognitive function in mice by increasing production of insulin-like growth factor-I in the hippocampus.
Topics: Animals; Antioxidants; Calcitonin Gene-Related Peptide; Capsaicin; Cognition; Ganglia, Spinal; Hippocampus; Immunohistochemistry; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Resveratrol; RNA, Messenger; Sensory Receptor Cells; Stilbenes | 2011 |
Occurrence of C-glucoside of resveratrol oligomers in Hopea parviflora.
Topics: Dipterocarpaceae; Glucosides; Plant Bark; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Changes of platelet antioxidative enzymes during oxidative stress: the protective effect of polyphenol-rich extract from berries of Aronia melanocarpa and grape seeds.
Topics: Adult; Antioxidants; Blood Platelets; Catalase; Cells, Cultured; Chromatography, High Pressure Liquid; Flavonoids; Fruit; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Male; Oxidative Stress; Phenols; Photinia; Plant Extracts; Resveratrol; Seeds; Stilbenes; Superoxide Dismutase; Vitis | 2011 |
The COPD pipeline VIII.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Chlorofluorocarbons; Clinical Trials as Topic; Human Genome Project; Humans; Metered Dose Inhalers; Pulmonary Disease, Chronic Obstructive; Resveratrol; Sirtuins; Stilbenes | 2011 |
[Resveratrol acts by modulating miRNAs].
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Cytokines; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; MicroRNAs; Models, Biological; Neoplasm Proteins; Prostaglandins; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Resveratrol; RNA, Neoplasm; Stilbenes | 2011 |
Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats.
Topics: Animals; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Fibronectins; Hypoglycemic Agents; Kidney; Male; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Smad Proteins; Stilbenes; Transforming Growth Factor beta | 2011 |
Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cetuximab; Colonic Neoplasms; Computational Biology; Drug Therapy, Combination; Female; Humans; Models, Biological; Monte Carlo Method; Nanoparticles; Resveratrol; Stilbenes; Thyroxine | 2011 |
Cognitive performances are selectively enhanced during chronic caloric restriction or resveratrol supplementation in a primate.
Topics: Animals; Caloric Restriction; Cheirogaleidae; Cognition; Hydrocortisone; Male; Memory; Motor Activity; Primates; Resveratrol; Stilbenes; Stress, Physiological | 2011 |
Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition.
Topics: Animals; Antioxidants; Apoptosis; Cell Movement; Epithelial-Mesenchymal Transition; Humans; Mice; Mice, Transgenic; Neoplastic Stem Cells; Pancreatic Neoplasms; Pluripotent Stem Cells; Proto-Oncogene Proteins p21(ras); Resveratrol; Stilbenes; Transcription Factors | 2011 |
Central antalgic activity of resveratrol.
Topics: Analgesics; Animals; Disease Models, Animal; Hyperalgesia; Injections, Intraventricular; Male; Motor Activity; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Reaction Time; Resveratrol; Stilbenes | 2010 |
SOCS-3 antagonizes pro-apoptotic effects of TRAIL and resveratrol in prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Down-Regulation; Humans; Male; Prostatic Neoplasms; Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; RNA, Small Interfering; Stilbenes; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation | 2011 |
Cardioprotective effect of resveratrol on lipopolysaccharide-induced oxidative stress in rat.
Topics: Animals; Antioxidants; Catalase; Disease Models, Animal; Endotoxemia; Heart; Heart Diseases; Lipid Peroxidation; Lipopolysaccharides; Male; Myocardium; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2011 |
Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts.
Topics: beta-Galactosidase; Cell Line; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dose-Response Relationship, Drug; Fibroblasts; Humans; Imidazoles; Ki-67 Antigen; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes | 2011 |
Comparative transcriptional pathway bioinformatic analysis of dietary restriction, Sir2, p53 and resveratrol life span extension in Drosophila.
Topics: Animals; Caloric Restriction; Computational Biology; Drosophila; Drosophila Proteins; Gene Expression Profiling; Gene Knockout Techniques; Histone Deacetylases; Juvenile Hormones; Longevity; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Tumor Suppressor Protein p53 | 2011 |
Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit.
Topics: Animals; Apoptosis; Cartilage; Chondrocytes; Cytoprotection; Disease Models, Animal; Female; In Situ Nick-End Labeling; Injections, Intra-Articular; Knee Joint; Male; Nitric Oxide; Osteoarthritis, Knee; Rabbits; Resveratrol; Stilbenes; Synovial Fluid; Time Factors | 2012 |
Malaysianol A, a new trimer resveratrol oligomer from the stem bark of Dryobalanops aromatica.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dipterocarpaceae; Drug Screening Assays, Antitumor; Flavonoids; Humans; Plant Bark; Plant Stems; Resveratrol; Stilbenes | 2011 |
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
Topics: Acetylesterase; Animals; Autophagy; Caenorhabditis elegans; Cell Line; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Humans; Mitochondria; Phosphorylation; Proteome; Resveratrol; Saccharomyces cerevisiae; Signal Transduction; Sirtuin 1; Spermidine; Stilbenes | 2011 |
Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.
Topics: Animals; Cell Movement; Cells, Cultured; Chemokine CCL20; Diabetes Mellitus, Type 1; Female; Flow Cytometry; Hypoglycemic Agents; Interleukin-17; Mice; Mice, Inbred NOD; Receptors, CCR6; Resveratrol; Stilbenes | 2011 |
The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Combined Modality Therapy; Flow Cytometry; Gangliosides; Immunoglobulin G; Immunotherapy; Interleukin-2; Leukocyte Common Antigens; Leukocytes; Mice; Mice, Inbred A; Neoplasm Recurrence, Local; Neuroblastoma; Resveratrol; Stilbenes; Survival; Tumor Burden | 2011 |
Is red wine a SAFE sip away from cardioprotection? Mechanisms involved in resveratrol- and melatonin-induced cardioprotection.
Topics: Animals; Blotting, Western; In Vitro Techniques; Male; Melatonin; Mice; Myocardial Infarction; Myocardium; Phosphorylation; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type II; Resveratrol; STAT3 Transcription Factor; Stilbenes; Wine | 2011 |
Stereoselective synthesis of an iodinated resveratrol analog: preliminary bioevaluation studies of the radioiodinated species.
Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Female; Humans; Iodine; Magnetic Resonance Spectroscopy; Mice; Resveratrol; Spectrophotometry, Infrared; Stereoisomerism; Stilbenes | 2011 |
Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Blotting, Western; Cataract; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Flow Cytometry; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Lens, Crystalline; Membrane Potential, Mitochondrial; Oxidative Stress; Polymerase Chain Reaction; Resveratrol; RNA; Stilbenes; Swine | 2011 |
[Synthesis and HIV-1 inhibitory activity of natural products isolated from Gnetum parvifolium and their analogues].
Topics: Anti-HIV Agents; Cells, Cultured; Drugs, Chinese Herbal; Gnetum; HIV-1; Inhibitory Concentration 50; Leukocytes, Mononuclear; Molecular Structure; Plants, Medicinal; Resveratrol; Stilbenes; Virus Replication | 2010 |
The extract from hop cones (Humulus lupulus) as a modulator of oxidative stress in blood platelets.
Topics: Antioxidants; Blood Platelets; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Humulus; Lipid Peroxidation; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Phenols; Plant Extracts; Protein Carbonylation; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Tyrosine | 2011 |
Regeneration of infarcted myocardium with resveratrol-modified cardiac stem cells.
Topics: Animals; Antioxidants; Biomarkers; Cell Proliferation; Cell- and Tissue-Based Therapy; Echocardiography; Heart; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Regeneration; Resveratrol; Stem Cell Transplantation; Stem Cells; Stilbenes | 2012 |
Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway.
Topics: Animals; Antioxidants; Azoxymethane; Colonic Neoplasms; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Quantum-chemical study of interactions of trans-resveratrol with guanine-thymine dinucleotide and DNA-nucleobases.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Cytosine; DNA; DNA Breaks; Guanine; Humans; Hydrogen Bonding; Models, Molecular; Neoplasms; Nucleic Acid Conformation; Quantum Theory; Resveratrol; Static Electricity; Stilbenes; Thermodynamics; Thymine; Vacuum; Water | 2011 |
Melanization of flavonoids by fungal and bacterial laccases.
Topics: Bacillus subtilis; Cryptococcus neoformans; Enzyme Inhibitors; Flavonoids; Laccase; Melanins; Resveratrol; Stilbenes | 2011 |
Characterization of trans-resveratrol-loaded lipid-core nanocapsules and tissue distribution studies in rats.
Topics: Animals; Antioxidants; Drug Stability; Gastrointestinal Tract; Hydrogen-Ion Concentration; Lipids; Male; Nanocapsules; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2010 |
Development and validation of an analytical method for the determination of trans- and cis-resveratrol in wine: analysis of its contents in 186 Portuguese red wines.
Topics: Chromatography, High Pressure Liquid; Isomerism; Portugal; Resveratrol; Stilbenes; Wine | 2011 |
Effects of resveratrol, a grape polyphenol, on uterine contraction and Ca²+ mobilization in rats in vivo and in vitro.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Cells, Cultured; Dinoprost; Dose-Response Relationship, Drug; Female; Flavonoids; Humans; In Vitro Techniques; Male; Myocytes, Smooth Muscle; Myosin Light Chains; Oxytocics; Oxytocin; Phenols; Phosphorylation; Polyphenols; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Uterine Contraction; Uterus; Vasodilator Agents; Vitis | 2011 |
Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Autophagy; Caenorhabditis elegans; Caloric Restriction; Cell Line, Tumor; Humans; Longevity; Resveratrol; RNA Interference; RNA, Small Interfering; Sirolimus; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2010 |
Resveratrol rescues cAMP-dependent anionic transport in the cystic fibrosis pancreatic cell line CFPAC1.
Topics: Animals; Anion Transport Proteins; Biological Transport; Cell Line; Cell Line, Tumor; Cell Membrane; Chloride Channels; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dogs; Epithelial Cells; Humans; Interleukin-8; Mutation; Resveratrol; Stilbenes | 2011 |
Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; CD28 Antigens; CD3 Complex; Cells, Cultured; Drugs, Chinese Herbal; Glucosides; Humans; Interleukin-17; Leukocytes, Mononuclear; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
Effect of dietary supplementation on the prognostic value of urinary and serum 8-isoprostaglandin F2α in chemically-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Biomarkers, Tumor; Carcinogens; Copper; Dietary Supplements; Dinoprost; Female; Genistein; Mammary Neoplasms, Experimental; Prognosis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Zinc | 2011 |
Resveratrol improves hippocampal atrophy in chronic fatigue mice by enhancing neurogenesis and inhibiting apoptosis of granular cells.
Topics: Animals; Apoptosis; Atrophy; Brain-Derived Neurotrophic Factor; Brucella abortus; Disease Models, Animal; Fatigue Syndrome, Chronic; Female; Hippocampus; Mice; Mice, Inbred BALB C; Neurogenesis; Neurons; Neuroprotective Agents; Phytotherapy; Plant Extracts; Resveratrol; RNA, Messenger; Stilbenes | 2011 |
Lack of effect of oral administration of resveratrol in LPS-induced systemic inflammation.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Chromatography, Liquid; Endotoxins; Inflammation; Interleukin-1beta; Lipid Peroxidation; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Sepsis; Stilbenes; Tandem Mass Spectrometry; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brain.
Topics: Acetylcholinesterase; Animals; Animals, Newborn; Antioxidants; Brain Damage, Chronic; Caspase 3; Cell Death; Central Nervous System Depressants; Cognition Disorders; Ethanol; Inflammation; Lipid Peroxidation; Male; Maze Learning; Memory; Nerve Degeneration; Neuroprotective Agents; NF-kappa B; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2011 |
Finding more active antioxidants and cancer chemoprevention agents by elongating the conjugated links of resveratrol.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Cell Cycle; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Molecular Structure; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
Protective effect of resveratrol derived from Polygonum cuspidatum and its liposomal form on nigral cells in parkinsonian rats.
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Fallopia japonica; Liposomes; Male; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Substantia Nigra | 2011 |
Exposure to resveratrol triggers pharmacological correction of fatty acid utilization in human fatty acid oxidation-deficient fibroblasts.
Topics: Acyl-CoA Dehydrogenase, Long-Chain; AMP-Activated Protein Kinase Kinases; Antioxidants; Carnitine O-Palmitoyltransferase; Cells, Cultured; Enzyme Activation; Fatty Acids; Fibroblasts; Gene Expression Regulation; Heat-Shock Proteins; Humans; Mutation; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Binding; Protein Kinases; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2011 |
Enrichment of (E)-resveratrol from peanut byproduct with molecularly imprinted polymers.
Topics: Arachis; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Polymers; Resveratrol; Solid Phase Microextraction; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2011 |
Anti-inflammatory effects of resveratrol and oligostilbenes from Vitis thunbergii var. taiwaniana against lipopolysaccharide-induced arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Humans; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Vitis | 2011 |
Resveratrol reduces the invasive growth and promotes the acquisition of a long-lasting differentiated phenotype in human glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Brain Neoplasms; Cell Differentiation; Cell Division; Cell Line, Tumor; Glioblastoma; Humans; Microscopy, Fluorescence; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Wound Healing | 2011 |
An automatic optosensing device for the simultaneous determination of resveratrol and piceid in wines.
Topics: Automation; Chromatography, High Pressure Liquid; Glucosides; Limit of Detection; Resveratrol; Solid Phase Extraction; Spectrometry, Fluorescence; Stilbenes; Wine | 2011 |
Comparative study of different methods to measure antioxidant activity of resveratrol in the presence of cyclodextrins.
Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Cyclodextrins; Limit of Detection; Oxidation-Reduction; Picrates; Reactive Oxygen Species; Reproducibility of Results; Resveratrol; Stilbenes; Sulfonic Acids; Thiazoles | 2011 |
Resveratrol metabolites do not elicit early pro-apoptotic mechanisms in neuroblastoma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Female; Humans; Mice; Mice, Nude; Neuroblastoma; Resveratrol; Stilbenes | 2011 |
Resveratrol inhibits the formation of multiple-layered β-sheet oligomers of the human islet amyloid polypeptide segment 22-27.
Topics: Binding, Competitive; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Oligopeptides; Protein Multimerization; Protein Stability; Protein Structure, Secondary; Resveratrol; Stilbenes; Thermodynamics | 2011 |
Resveratrol modulates the malignant properties of cutaneous melanoma through changes in the activation and attenuation of the antiapoptotic protooncogenic protein Akt/PKB.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Enzyme Activation; Female; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resveratrol; Skin Neoplasms; Stilbenes | 2011 |
Preparation of molecularly imprinted polymers for the selective recognition of the bioactive polyphenol, (E)-resveratrol.
Topics: Chromatography, High Pressure Liquid; Models, Molecular; Molecular Imprinting; Phenols; Polymers; Pyridines; Resveratrol; Solid Phase Extraction; Stilbenes | 2011 |
A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice.
Topics: Acute-Phase Proteins; Animals; Antioxidants; Apolipoprotein E3; Ascorbic Acid; Atherosclerosis; Biomarkers; C-Reactive Protein; Carotenoids; Catechin; Diet; Female; Fish Oils; Humans; Lycopene; Male; Mice; Mice, Transgenic; Resveratrol; Risk Factors; Stilbenes; Vitamin E | 2011 |
Chronic estradiol-17β exposure increases superoxide production in the rostral ventrolateral medulla and causes hypertension: reversal by resveratrol.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Estradiol; Estrogens; Heart Rate; Hypertension; Male; Medulla Oblongata; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxides | 2011 |
Zebrafish as a model organism to evaluate drugs potentially able to modulate sirtuin expression.
Topics: Animals; Enzyme Inhibitors; Female; Gene Expression Regulation; Male; Models, Animal; Phylogeny; Resveratrol; Sirtuins; Stilbenes; Zebrafish; Zebrafish Proteins | 2011 |
Resveratrol protects leukemic cells against cytotoxicity induced by proteasome inhibitors via induction of FOXO1 and p27Kip1.
Topics: Apoptosis; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27; Cytoprotection; Cytotoxins; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia; Proteasome Inhibitors; Resveratrol; Stilbenes; U937 Cells | 2011 |
Extracellular HIV-1 Tat upregulates TNF-α dependent MCP-1/CCL2 production via activation of ERK1/2 pathway in rat hippocampal slice cultures: inhibition by resveratrol, a polyphenolic phytostilbene.
Topics: Analysis of Variance; Animals; Antibodies, Neutralizing; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Hippocampus; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; tat Gene Products, Human Immunodeficiency Virus; Tumor Necrosis Factor-alpha | 2011 |
Thermally treated wine retains vasodilatory activity in rat and guinea pig aorta.
Topics: Animals; Antioxidants; Aorta, Thoracic; Ethanol; Flavonoids; Guinea Pigs; Hot Temperature; In Vitro Techniques; Male; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Species Specificity; Stilbenes; Vasodilation; Vasodilator Agents; Wine | 2011 |
Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli.
Topics: Acyltransferases; Arabidopsis; Biosynthetic Pathways; Coenzyme A Ligases; Coumaric Acids; Escherichia coli; Flavanones; Flavonoids; Genetic Engineering; Methyltransferases; Plants; Resveratrol; Stilbenes | 2011 |
Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method.
Topics: Antineoplastic Agents; Carcinoid Tumor; Cell Line, Tumor; Dose-Response Relationship, Drug; High-Throughput Screening Assays; Humans; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2011 |
Improved resistance against Botrytis cinerea by grapevine-associated bacteria that induce a prime oxidative burst and phytoalexin production.
Topics: Acinetobacter; Bacillus subtilis; Botrytis; Cell Death; Hydrogen Peroxide; Pantoea; Phytoalexins; Plant Diseases; Plant Immunity; Plant Leaves; Plant Roots; Pseudomonas fluorescens; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Sesquiterpenes; Signal Transduction; Stilbenes; Vitis | 2011 |
Heat stress-induced hepatotoxicity and its prevention by resveratrol in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Heat-Shock Response; Hot Temperature; Liver; Liver Diseases; Male; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2011 |
DIGE analysis of proteome changes accompanying large resveratrol production by grapevine (Vitis vinifera cv. Gamay) cell cultures in response to methyl-β-cyclodextrin and methyl jasmonate elicitors.
Topics: Acetates; Acyltransferases; beta-Cyclodextrins; Cells, Cultured; Cyclopentanes; Electrophoresis, Gel, Two-Dimensional; Gene Expression Profiling; Gene Expression Regulation, Plant; Oxylipins; Proteome; Resveratrol; Stilbenes; Vitis | 2011 |
Food: The omnivore's labyrinth.
Topics: Animals; Brassica; Breeding; Cooking; Curcumin; Diet; Fruit; Genetic Variation; Genistein; Genome, Human; Humans; Isothiocyanates; Metagenome; Mice; Neoplasms; Phytotherapy; Rats; Reproducibility of Results; Resveratrol; Risk Management; Stilbenes; Sulfoxides; Thiocyanates; Time Factors; Vegetables | 2011 |
Population pharmacokinetic modeling of trans-resveratrol and its glucuronide and sulfate conjugates after oral and intravenous administration in rats.
Topics: Administration, Oral; Animals; Glucuronides; Infusions, Intravenous; Male; Models, Chemical; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfates; Vasodilator Agents | 2011 |
[Optimization of ultrahigh pressure extraction for polydatin and resveratrol from Polygonum cuspidatum by using uniform design].
Topics: Calibration; Chemical Fractionation; Fallopia japonica; Glucosides; Pressure; Reproducibility of Results; Resveratrol; Solvents; Stilbenes; Time Factors | 2010 |
Quantitation of resveratrol in red wines by means of stable isotope dilution analysis-ultra-performance liquid chromatography-Quan-time-of-flight mass spectrometry and cross validation.
Topics: Chromatography, High Pressure Liquid; Deuterium; Indicator Dilution Techniques; Mass Spectrometry; Reference Standards; Reproducibility of Results; Resveratrol; Stereoisomerism; Stilbenes; Time Factors; Wine | 2011 |
Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling.
Topics: Animals; Antioxidants; Base Sequence; Cytokines; Diabetic Nephropathies; DNA Primers; Hyperglycemia; Inflammation Mediators; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Kidney; Male; Microscopy, Electron, Transmission; NF-E2-Related Factor 2; Oxidative Stress; Polymerase Chain Reaction; Proteins; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2011 |
Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Base Sequence; DNA Primers; Down-Regulation; Inflammation; Male; Mice; Mice, Inbred C57BL; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Synthesis, biological evaluation, and molecular docking studies of resveratrol derivatives possessing chalcone moiety as potential antitubulin agents.
Topics: Binding Sites; Cell Line, Tumor; Chalcone; Dose-Response Relationship, Drug; Humans; Protein Binding; Resveratrol; Stilbenes; Structure-Activity Relationship; Tubulin Modulators | 2011 |
High-yield resveratrol production in engineered Escherichia coli.
Topics: Acyltransferases; Chromatography, High Pressure Liquid; Escherichia coli; Gene Expression; Metabolic Networks and Pathways; Plant Proteins; Recombinant Proteins; Resveratrol; Stilbenes | 2011 |
Resveratrol impairs the release of steroid-resistant cytokines from bacterial endotoxin-exposed alveolar macrophages in chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Lipopolysaccharides; Macrophages, Alveolar; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Resveratrol; Stilbenes | 2011 |
Protective effects of resveratrol on calcium-induced oxidative stress in rat heart mitochondria.
Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Cardiovascular Diseases; Glutathione; Iron; Male; Mitochondria, Heart; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2011 |
Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice.
Topics: Aging; Animals; Antioxidants; Dietary Supplements; Disease Models, Animal; Follow-Up Studies; Immunoblotting; Isometric Contraction; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Resveratrol; Ribonucleotide Reductases; Sarcopenia; Stilbenes; Time Factors | 2011 |
Occurrence and estimation of trans-resveratrol in one-year-old canes from seven major Chinese grape producing regions.
Topics: China; Genotype; Geography; Resveratrol; Stilbenes; Vitis | 2011 |
The combination of resveratrol and conjugated linoleic acid is not useful in preventing obesity.
Topics: Adipose Tissue, White; Animals; Area Under Curve; Blood Glucose; Body Weight; Drug Evaluation, Preclinical; Drug Therapy, Combination; Energy Intake; Glucose Tolerance Test; Linoleic Acids, Conjugated; Lipids; Male; Obesity; Organ Size; Rats; Rats, Wistar; Resveratrol; Stilbenes; Treatment Failure | 2011 |
Effect of resveratrol on bone formation in the expanded inter-premaxillary suture: early bone changes.
Topics: Animals; Antioxidants; Cell Count; Cranial Sutures; Dimethyl Sulfoxide; Drug Carriers; Male; Maxilla; Orthodontic Wires; Osteoblasts; Osteogenesis; Palatal Expansion Technique; Palate; Rats; Rats, Wistar; Resveratrol; Solvents; Stilbenes; Time Factors | 2011 |
Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Coumaric Acids; Curcuma; Curcumin; DNA; Fibroblasts; Free Radicals; Gingiva; Humans; Periodontal Ligament; Phloretin; Plant Preparations; Polyphenols; Resveratrol; Stilbenes | 2011 |
Longevity-relevant regulation of autophagy at the level of the acetylproteome.
Topics: Acetylation; Animals; Autophagy; Caenorhabditis elegans; Cytoplasm; Drosophila melanogaster; Humans; Longevity; Proteome; Proteomics; Resveratrol; Saccharomyces cerevisiae; Sirtuin 1; Spermidine; Stilbenes; Subcellular Fractions | 2011 |
Evaluation of renal protective effects of the green-tea (EGCG) and red grape resveratrol: role of oxidative stress and inflammatory cytokines.
Topics: Animals; Camellia sinensis; Catechin; Cisplatin; Cross-Linking Reagents; Cytokines; Dose-Response Relationship, Drug; Gene Expression Regulation; Kidney Diseases; Lipid Peroxidation; Oxidative Stress; Rats; Resveratrol; Stilbenes; Vitis | 2011 |
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Cytokines; Diethylnitrosamine; Female; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Phenobarbital; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.
Topics: Anticarcinogenic Agents; Caco-2 Cells; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Induction; Flavonoids; Glucuronides; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2011 |
Endocytosis of resveratrol via lipid rafts and activation of downstream signaling pathways in cancer cells.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Apoptosis; beta-Cyclodextrins; Blotting, Western; Colonic Neoplasms; Endocytosis; Extracellular Signal-Regulated MAP Kinases; Filipin; Flow Cytometry; Focal Adhesion Kinase 1; GRB2 Adaptor Protein; Humans; Immunoenzyme Techniques; Immunoprecipitation; Integrin alphaVbeta3; Membrane Microdomains; Nystatin; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; ras Proteins; Resveratrol; Signal Transduction; Son of Sevenless Proteins; Stilbenes; Tumor Cells, Cultured | 2011 |
Caffeic acid phenethyl ester suppresses the production of adipocytokines, leptin, tumor necrosis factor -alpha and resistin, during differentiation to adipocytes in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Animals; Caffeic Acids; Cell Differentiation; Glycerolphosphate Dehydrogenase; Insulin Receptor Substrate Proteins; Leptin; Mice; Phenylethyl Alcohol; Propolis; Resistin; Resveratrol; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol enhances 5-hydroxytryptamine type 3A receptor-mediated ion currents: the role of arginine 222 residue in pre-transmembrane domain I.
Topics: Animals; Arginine; Fruit; Ion Channel Gating; Ion Transport; Mice; Mutagenesis, Site-Directed; Mutation; Neurotransmitter Agents; Oocytes; Patch-Clamp Techniques; Plant Extracts; Protein Structure, Tertiary; Receptors, Serotonin, 5-HT3; Resveratrol; RNA, Complementary; Serotonin; Stilbenes; Synaptic Membranes; Synaptic Transmission; Vitis; Wine; Xenopus | 2011 |
Resveratrol derivatives from Vatica albiramis.
Topics: Dipterocarpaceae; Heterocyclic Compounds, 4 or More Rings; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Stems; Resveratrol; Stilbenes | 2011 |
Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; E2F1 Transcription Factor; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Stilbenes; Transfection; Up-Regulation | 2011 |
Resveratrol induces SIRT1- and energy-stress-independent inhibition of tumor cell regrowth after low-dose platinum treatment.
Topics: Antineoplastic Agents; Carboplatin; Cell Cycle; Cell Death; Cell Line, Tumor; Cisplatin; Female; Humans; Ovarian Neoplasms; PTEN Phosphohydrolase; Resveratrol; Sirtuin 1; Stilbenes; Stress, Physiological | 2011 |
Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chloride Channels; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme-Linked Immunosorbent Assay; Epithelium; Interleukin-8; Mice; Mice, Inbred C57BL; Mice, Knockout; Mucociliary Clearance; Phosphorylation; Protein Structure, Tertiary; Resveratrol; Stilbenes | 2011 |
Resveratrol induces cellular senescence with attenuated mono-ubiquitination of histone H2B in glioma cells.
Topics: Animals; Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Gene Knockdown Techniques; Glioma; Histones; Humans; Mice; Mice, Nude; Resveratrol; Stilbenes; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays | 2011 |
Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis.
Topics: Adenylate Kinase; Animals; Antioxidants; Energy Metabolism; Enzyme Activation; Glucose; Homeostasis; Insulin; Insulin-Secreting Cells; Liver; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2011 |
Activation energy of light induced isomerization of resveratrol.
Topics: Fluorescence; Kinetics; Molecular Structure; Resveratrol; Spectrometry, Fluorescence; Stereoisomerism; Stilbenes; Temperature; Time Factors; Ultraviolet Rays | 2011 |
Resveratrol triggers apoptosis through regulating ceramide metabolizing genes in human K562 chronic myeloid leukemia cells.
Topics: Apoptosis; Ceramides; Down-Regulation; Glucosylceramides; Glucosyltransferases; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lysophospholipids; Morpholines; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; RNA, Neoplasm; Sphingosine; Stilbenes; Up-Regulation | 2011 |
Resveratrol preserves cardiac function, but does not prevent endothelial dysfunction or pulmonary inflammation after environmental tobacco smoke exposure.
Topics: Administration, Oral; Animals; Aorta, Abdominal; Blood Pressure; Bronchoalveolar Lavage Fluid; C-Reactive Protein; Cardiovascular Physiological Phenomena; Cotinine; Cytochrome P-450 CYP1A1; Echocardiography; Endothelium, Vascular; Environmental Exposure; Leukocyte Count; Leukocyte Elastase; Male; Nitrates; Nitrites; Oxidative Stress; Resveratrol; Stilbenes; Swine; Tobacco Smoke Pollution; Tyrosine; Ventricular Function, Left | 2011 |
Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis.
Topics: Aged; Animals; Antineoplastic Agents, Phytogenic; Astrocytoma; Brain Neoplasms; Chemoradiotherapy; Female; Glioblastoma; Humans; Male; Mice; Mice, SCID; Middle Aged; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol.
Topics: Amino Acid Sequence; Antigens, Surface; Apoptosis; bcl-2-Associated X Protein; Biflavonoids; Caspases; Catechin; Cell Shape; Cell Survival; Cytochromes c; Endothelial Cells; Glycation End Products, Advanced; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mass Spectrometry; Milk Proteins; Molecular Sequence Data; Peptides; Phosphorylation; Plasmids; Proanthocyanidins; Protective Agents; Protein Binding; Resveratrol; RNA, Small Interfering; Seeds; Stilbenes; Transduction, Genetic; Umbilical Veins; Vitis | 2011 |
Resveratrol induces mitochondria-mediated AIF and to a lesser extent caspase-9-dependent apoptosis in human lung adenocarcinoma ASTC-a-1 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Nucleus; Cell Survival; Enzyme Activation; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Protein Transport; Resveratrol; RNA Interference; Stilbenes | 2011 |
Profiling of resveratrol oligomers, important stress metabolites, accumulating in the leaves of hybrid Vitis vinifera (Merzling × Teroldego) genotypes infected with Plasmopara viticola.
Topics: Caffeic Acids; Catechin; Dimerization; Genotype; Hybridization, Genetic; Oomycetes; Plant Diseases; Plant Leaves; Resveratrol; Stilbenes; Vitis | 2011 |
Hepatic glucuronidation of resveratrol: interspecies comparison of enzyme kinetic profiles in human, mouse, rat, and dog.
Topics: Animals; Dogs; Enzyme Inhibitors; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Liver; Male; Mice; Microsomes, Liver; Models, Animal; Models, Theoretical; Rats; Rats, Wistar; Resveratrol; Species Specificity; Stilbenes | 2011 |
[Inhibitory effect of resveratrol against enterovirus type 71 in vitro].
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drugs, Chinese Herbal; Enterovirus; Resveratrol; Stilbenes; Vero Cells | 2011 |
Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Buthionine Sulfoximine; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Mice; PPAR gamma; Resveratrol; Stilbenes; Triglycerides | 2011 |
Resveratrol inhibits periodontal pathogens in vitro.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Colony Count, Microbial; Microbial Sensitivity Tests; Porphyromonas gingivalis; Resveratrol; Stilbenes | 2011 |
Resveratrol (trans-3,5,4'-trihydroxystilbene) suppresses EL4 tumor growth by induction of apoptosis involving reciprocal regulation of SIRT1 and NF-κB.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Neoplastic; Lymphoma; Mice; Mice, Inbred NOD; Mice, SCID; NF-kappa B; Receptors, Aryl Hydrocarbon; Resveratrol; Sirtuin 1; Stilbenes | 2011 |
The role of calcium channel blockers and resveratrol in the prevention of paraquat-induced parkinsonism in Drosophila melanogaster: a locomotor analysis.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Disease Models, Animal; Dopamine; Drosophila melanogaster; Nerve Degeneration; Paraquat; Parkinsonian Disorders; Resveratrol; Stilbenes; Substantia Nigra | 2011 |
Identification of novel pregnane X receptor activators from traditional Chinese medicines.
Topics: 4-Butyrolactone; Berberine; Cyclooctanes; Cytochrome P-450 CYP3A; Dioxoles; Drugs, Chinese Herbal; Genes, Reporter; Hep G2 Cells; Herb-Drug Interactions; Humans; Lignans; Magnoliopsida; Medicine, Chinese Traditional; Plants, Medicinal; Pregnane X Receptor; Receptors, Steroid; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2011 |
Drug loading in Pluronic® micelles made by solvent casting and equilibrium methods using resveratrol as a model drug.
Topics: Micelles; Poloxamer; Resveratrol; Solubility; Solvents; Stilbenes | 2010 |
Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Disease Models, Animal; Extracellular Matrix; Inflammation; Inflammation Mediators; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes; Transcription Factor RelA | 2011 |
Resveratrol regulates lipolysis via adipose triglyceride lipase.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Cell Line; Fatty Acids, Nonesterified; Humans; Isoproterenol; Lipase; Lipolysis; Male; Mice; Mice, Knockout; Resveratrol; Sterol Esterase; Stilbenes; Triglycerides | 2012 |
Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: inhibition by resveratrol.
Topics: Adenoviridae; Aging; Animals; Aorta; Cells, Cultured; Endothelial Cells; Humans; Immunoblotting; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred WKY; Resveratrol; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Stilbenes; Superoxides | 2011 |
[Study on preparation and characterization of resveratrol solid lipid nanoparticles and its anticancer effects in vitro].
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Glycerides; Hep G2 Cells; Humans; Lipids; Nanoparticles; Particle Size; Phospholipids; Poloxamer; Resveratrol; Stilbenes; Surface Properties | 2010 |
The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cytochromes c; Dequalinium; Female; Humans; Liposomes; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Phosphatidylethanolamines; Polyethylene Glycols; Resveratrol; Stilbenes | 2011 |
Comparison of thermal effects of stilbenoid analogs in lipid bilayers using differential scanning calorimetry and molecular dynamics: correlation of thermal effects and topographical position with antioxidant activity.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antioxidants; Calorimetry, Differential Scanning; Hydroxides; Isomerism; Lipid Bilayers; Molecular Dynamics Simulation; Phenols; Resveratrol; Stilbenes; Temperature; Thermodynamics | 2011 |
Structure-activity relationship of resveratrol and its analogue, 4,4'-dihydroxy-trans-stilbene, toward the endothelin axis in human endothelial cells.
Topics: Antioxidants; Aspartic Acid Endopeptidases; Cell Line; Endothelin-1; Endothelin-Converting Enzymes; Human Umbilical Vein Endothelial Cells; Humans; Lipid Peroxidation; Metalloendopeptidases; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Structure-Activity Relationship | 2011 |
The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/differentiation-1.
Topics: Activating Transcription Factor 3; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Genistein; Humans; Inhibitor of Differentiation Protein 1; Resveratrol; Stilbenes; Up-Regulation | 2011 |
Response of blood platelets to resveratrol during a model of hyperhomocysteinemia.
Topics: Adult; Antioxidants; Blood Platelets; Homocysteine; Humans; Hyperhomocysteinemia; Platelet Aggregation; Resveratrol; Stilbenes; Superoxides; Young Adult | 2011 |
Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs.
Topics: Amyloidosis; Antioxidants; Cell Line; Humans; Myocytes, Cardiac; Prealbumin; Resveratrol; Stilbenes | 2011 |
Comparative inhibitory activity of the stilbenes resveratrol and oxyresveratrol on African swine fever virus replication.
Topics: African Swine Fever Virus; Animals; Antioxidants; Antiviral Agents; Cell Line; Chlorocebus aethiops; DNA Replication; Phytotherapy; Plant Extracts; Polymerase Chain Reaction; Protein Synthesis Inhibitors; Resveratrol; Stilbenes; Virus Replication | 2011 |
Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18.
Topics: Animals; Cell Adhesion; Cell Proliferation; Endothelium; Inflammation; Interleukin-18; Liver; Liver Neoplasms; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Microvessels; Models, Biological; Neoplasm Transplantation; Resveratrol; Stilbenes; Tumor Microenvironment; Vascular Cell Adhesion Molecule-1 | 2011 |
Stepwise increase of resveratrol biosynthesis in yeast Saccharomyces cerevisiae by metabolic engineering.
Topics: Ammonia-Lyases; Bacterial Proteins; Biological Transport, Active; Coumaric Acids; Culture Media; Monosaccharide Transport Proteins; Organisms, Genetically Modified; Propionates; Resveratrol; Rhodobacter sphaeroides; Saccharomyces cerevisiae; Stilbenes; Sucrose; Wine | 2011 |
Simultaneous analysis of serotonin, melatonin, piceid and resveratrol in fruits using liquid chromatography tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Citrus sinensis; Fruit; Glucosides; Melatonin; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Serotonin; Stilbenes; Tandem Mass Spectrometry; Vitis | 2011 |
The effect of antioxidants on the production of pro-inflammatory cytokines and orthodontic tooth movement.
Topics: Acetylcysteine; Animals; Antioxidants; Cells, Cultured; Fibroblasts; Humans; Hypoxia; Inflammation; Inflammation Mediators; Interleukin-1beta; Male; Molar; Periodontal Ligament; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Mechanical; Tooth Mobility; Tumor Necrosis Factor-alpha; Up-Regulation | 2011 |
Effect of resveratrol on platelet activation in hypercholesterolemic rats: CD40-CD40L system as a potential target.
Topics: Animals; Body Weight; CD40 Antigens; CD40 Ligand; Cholesterol; Hypercholesterolemia; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2011 |
Resveratrol modifies risk factors for coronary artery disease in swine with metabolic syndrome and myocardial ischemia.
Topics: Animals; Biomarkers; Cholesterol; Coronary Artery Disease; Diet; Dietary Supplements; Fatty Acids, Nonesterified; Gene Expression Regulation; Glucose Tolerance Test; Glucose Transporter Type 4; Heart; Inflammation; Insulin; Magnetic Resonance Imaging; Metabolic Syndrome; Microvessels; Muscle Cells; Myocardial Ischemia; Oxidation-Reduction; Protein Transport; Resveratrol; Risk Factors; Stilbenes; Swine | 2011 |
Resveratrol suppresses apoptosis in intact human cardiac tissue - in vitro model simulating extracorporeal circulation.
Topics: Aged; Apoptosis; Biopsy; Caspase 3; Cytokines; Extracorporeal Circulation; Female; Gene Expression Regulation; Heart Arrest, Induced; Humans; Immunohistochemistry; In Vitro Techniques; Male; Middle Aged; Myocardial Reperfusion Injury; Myocytes, Cardiac; Perfusion; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protective Agents; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Time Factors | 2011 |
The red wine polyphenol resveratrol shows promising potential for the treatment of nucleus pulposus-mediated pain in vitro and in vivo.
Topics: Adult; Aged; Analgesics; Animals; Anti-Inflammatory Agents; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Interleukin-8; Intervertebral Disc; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Middle Aged; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pain; Pain Measurement; Radiculopathy; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Toll-Like Receptor 2; Wine; Young Adult | 2011 |
Complexes of the outer mitochondrial membrane protein mitoNEET with resveratrol-3-sulfate.
Topics: Calorimetry; Dimerization; Humans; Iron-Sulfur Proteins; Mitochondrial Membranes; Mitochondrial Proteins; Models, Molecular; Oxidation-Reduction; Protein Binding; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Thermodynamics | 2011 |
SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53.
Topics: Acetylation; Acute Kidney Injury; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; bcl-X Protein; Carbazoles; Caspase 3; Cisplatin; Enzyme Activation; Hepatitis A Virus Cellular Receptor 1; Kidney Tubules, Proximal; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2011 |
Development of a liquid chromatography/mass spectrometry methodology to separate, detect, characterize and quantify PEG-resveratrol prodrugs and the conjugation reaction precursors and intermediates.
Topics: Chromatography, Liquid; Mass Spectrometry; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Polyethylene Glycols; Prodrugs; Reproducibility of Results; Resveratrol; Stilbenes | 2011 |
Effect of ZnO#ZnS QDs heterojunctures on the stilbenes-plasma proteins interactions.
Topics: Animals; Binding Sites; Biological Availability; Blood Proteins; Cattle; Glucosides; Kinetics; Particle Size; Protein Binding; Quantum Dots; Resveratrol; Stilbenes; Zinc Oxide; Zinc Sulfate | 2011 |
The TRIF/TBK1/IRF-3 activation pathway is the primary inhibitory target of resveratrol, contributing to its broad-spectrum anti-inflammatory effects.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Nucleus; Cells, Cultured; Coloring Agents; Genes, Reporter; Inflammation; Interferon Regulatory Factor-3; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Plasmids; Protein Serine-Threonine Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Tetrazolium Salts; Thiazoles | 2011 |
Multiple beneficial effects of resveratrol and their chemical-biochemical basis.
Topics: Anti-Bacterial Agents; Basidiomycota; Fabaceae; Formaldehyde; Models, Chemical; Pseudomonas; Resveratrol; Stilbenes | 2011 |
Ischemic insult induced apoptotic changes in PC12 cells: protection by trans resveratrol.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Caspase 3; Glucose; Glutathione; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxidation; Neurons; Neuroprotective Agents; Oxidative Stress; Oxygen; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Transcription, Genetic | 2011 |
Resveratrol prevents bradykinin-induced contraction of rat urinary bladders by decreasing prostaglandin production and calcium influx.
Topics: Animals; Bradykinin; Calcium; Calcium Channel Agonists; Cyclooxygenase Inhibitors; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Potassium; Prostaglandins; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Urinary Bladder | 2011 |
Resveratrol potentiates grape seed extract induced human colon cancer cell apoptosis.
Topics: Apoptosis; Cell Line, Tumor; Cell Separation; Chromatography, Liquid; Colonic Neoplasms; Flow Cytometry; Humans; Mass Spectrometry; Plant Extracts; Resveratrol; Seeds; Stilbenes | 2011 |
Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats.
Topics: Animals; Avoidance Learning; Male; Maze Learning; Mecamylamine; Memory Disorders; Rats; Rats, Wistar; Reaction Time; Resveratrol; Scopolamine; Stilbenes | 2011 |
Resveratrol dietary supplementation shortens the free-running circadian period and decreases body temperature in a prosimian primate.
Topics: Animals; Antioxidants; Body Temperature; Cheirogaleidae; Circadian Rhythm; Dietary Supplements; Female; Motor Activity; Resveratrol; Stilbenes | 2011 |
Resveratrol attenuates high-fat diet-induced insulin resistance by influencing skeletal muscle lipid transport and subsarcolemmal mitochondrial β-oxidation.
Topics: Animals; Biological Transport; Diet, High-Fat; Down-Regulation; Insulin Resistance; Lipid Metabolism; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Resveratrol; Sarcolemma; Stilbenes | 2011 |
Curcumin and resveratrol synergistically stimulate p21 and regulate cox-2 by maintaining adequate zinc levels during lung carcinogenesis.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Blotting, Western; Body Weight; Carcinogens; Curcumin; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Disease Progression; Drug Synergism; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Organ Size; Resveratrol; Stilbenes; Zinc | 2011 |
Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Drinking; Eating; Endothelium, Vascular; Heart; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Organ Size; Oxidative Stress; Rats; Rats, Inbred SHR; Resveratrol; Stilbenes; Tyrosine | 2011 |
Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
Topics: Animals; Antioxidants; Blotting, Western; Cell Differentiation; Cell Line; Creatine Kinase; Electroporation; Fibroblasts; Fibrosis; Histones; Immunohistochemistry; Indicators and Reagents; L-Lactate Dehydrogenase; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2011 |
Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo.
Topics: Adenocarcinoma; Administration, Oral; Animals; Body Composition; Cachexia; Cell Line, Tumor; Dose-Response Relationship, Drug; Echocardiography; Female; Gene Expression Regulation, Enzymologic; Heart; Mice; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Myocardium; Neoplasm Transplantation; Random Allocation; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor RelA; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Weight Loss | 2011 |
Preventing bone loss and weight gain with combinations of vitamin D and phytochemicals.
Topics: Adipose Tissue; Adiposity; Animals; Bone Density; Bone Diseases, Metabolic; Diet; Dietary Supplements; Drug Combinations; Female; Femur; Genistein; Ovariectomy; Phytotherapy; Quercetin; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Vitamin D; Weight Gain | 2011 |
Antioxidant effect of trans-resveratrol in cultured human retinal pigment epithelial cells.
Topics: Antioxidants; Catalase; Cells, Cultured; Dietary Supplements; Dose-Response Relationship, Drug; Free Radical Scavengers; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Retinal Pigment Epithelium; Stilbenes; Superoxide Dismutase | 2011 |
Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats.
Topics: Analysis of Variance; Animals; Antioxidants; Arterioles; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dose-Response Relationship, Drug; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Oxidative Stress; Pia Mater; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Vasodilation; Vasodilator Agents | 2011 |
Resveratrol increases glucose induced GLP-1 secretion in mice: a mechanism which contributes to the glycemic control.
Topics: Animals; Blood Glucose; Dietary Fats; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Intolerance; Inflammation; Intestines; Male; Metagenome; Mice; Mice, Inbred C57BL; Receptors, Glucagon; Resveratrol; Stilbenes; Time Factors | 2011 |
Resveratrol-induced apoptosis is enhanced in low pH environments associated with cancer.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Chelating Agents; Copper; DNA Damage; DNA Fragmentation; Histones; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lymphocytes; Models, Biological; Pancreatic Neoplasms; Resveratrol; Stilbenes; Tumor Microenvironment | 2012 |
Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHβ gene expression by a SirT1-independent pathway in LβT2 gonadotrope cells.
Topics: Animals; Antioxidants; Cell Line; Follicle Stimulating Hormone, beta Subunit; Gene Expression; Gene Expression Profiling; Gonadotrophs; Mice; Oligonucleotide Array Sequence Analysis; Phosphorylation; Resveratrol; RNA, Messenger; Sirtuin 1; Smad2 Protein; Smad3 Protein; Stilbenes | 2011 |
Resveratrol enhances the expression of death receptor Fas/CD95 and induces differentiation and apoptosis in anaplastic large-cell lymphoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Differentiation; Cell Line, Tumor; DNA Fragmentation; fas Receptor; Humans; Lymphoma, Large-Cell, Anaplastic; Resveratrol; Stilbenes | 2011 |
Surfactant-assisted controlled release of hydrophobic drugs using anionic surfactant templated mesoporous silica nanoparticles.
Topics: Anions; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Porosity; Resveratrol; Silicon Dioxide; Stilbenes; Surface-Active Agents | 2011 |
Resveratrol inhibits genistein-induced multi-drug resistance protein 2 (MRP2) expression in HepG2 cells.
Topics: Base Sequence; DNA Primers; Drug Interactions; Gene Expression; Genes, Reporter; Genistein; Hep G2 Cells; Humans; Luciferases; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Promoter Regions, Genetic; Resveratrol; Retinoid X Receptor alpha; RNA, Messenger; Stilbenes; Vacuoles | 2011 |
Resveratrol may be beneficial in treatment of diabetic foot syndrome.
Topics: Diabetic Foot; Dietary Supplements; Humans; Insulin Resistance; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Wound Healing | 2011 |
Autophagy interplay with apoptosis and cell cycle regulation in the growth inhibiting effect of resveratrol in glioma cells.
Topics: Apoptosis; Autophagy; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Neoplastic Stem Cells; Phagosomes; Resveratrol; Stilbenes | 2011 |
Resveratrol restores Nrf2 level and prevents ethanol-induced toxic effects in the cerebellum of a rodent model of fetal alcohol spectrum disorders.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Female; Fetal Alcohol Spectrum Disorders; In Situ Nick-End Labeling; NF-E2-Related Factor 2; Pregnancy; Rats; Rats, Long-Evans; Reactive Oxygen Species; Resveratrol; Stilbenes | 2011 |
Organic chemistry: Triumph for unnatural synthesis.
Topics: Biological Products; Bromine; Flavonoids; Halogenation; Humans; Isomerism; Phenols; Polyphenols; Resveratrol; Stilbenes | 2011 |
Regioselective reactions for programmable resveratrol oligomer synthesis.
Topics: Biological Products; Bromine; Chemistry, Pharmaceutical; Flavonoids; Halogenation; Indicators and Reagents; Isomerism; Phenols; Polycyclic Compounds; Polyphenols; Resveratrol; Stilbenes; Substrate Specificity; Terpenes | 2011 |
Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Gene Expression; Male; Oxidative Stress; Rats; Rats, Long-Evans; Resveratrol; Stilbenes | 2011 |
Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain.
Topics: Acetylation; Animals; Antioxidants; Blotting, Western; Caloric Restriction; Cells, Cultured; Disease Models, Animal; Electron Transport Chain Complex Proteins; Electron Transport Complex III; Humans; Hydrogen Peroxide; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; NAD; NADH Dehydrogenase; Niacinamide; Oxidative Stress; Proteomics; Rats; Rats, Inbred F344; Resveratrol; Sirtuins; Stilbenes | 2011 |
Seeking the fountain of youth.
Topics: Antioxidants; Caloric Restriction; Humans; Life Expectancy; Longevity; Resveratrol; Sirtuins; Stilbenes | 2011 |
Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; BRCA1 Protein; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; Cells, Cultured; Comet Assay; DNA Damage; Head and Neck Neoplasms; Histones; Humans; Immunoblotting; Immunohistochemistry; Male; Mice; Mice, Nude; Mutation; Resveratrol; Smad4 Protein; Stilbenes; Transfection; Xenograft Model Antitumor Assays | 2011 |
Modulatory effect of resveratrol on SIRT1, SIRT3, SIRT4, PGC1α and NAMPT gene expression profiles in wild-type adult zebrafish liver.
Topics: Analysis of Variance; Animals; DNA Primers; Gene Expression Profiling; Gene Expression Regulation; Liver; NAD; Nicotinamide Phosphoribosyltransferase; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Sirtuin 3; Stilbenes; Transcription Factors; Zebrafish | 2012 |
Metabolites and tissue distribution of resveratrol in the pig.
Topics: Animals; Gastrointestinal Tract; Resveratrol; Stilbenes; Swine; Tissue Distribution | 2011 |
Trans-resveratrol simultaneously increases cytoplasmic Ca(2+) levels and nitric oxide release in human endothelial cells.
Topics: AMP-Activated Protein Kinases; Calcium; Cells, Cultured; Cytoplasm; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes | 2011 |
Resveratrol induces p53-independent, X-linked inhibitor of apoptosis protein (XIAP)-mediated Bax protein oligomerization on mitochondria to initiate cytochrome c release and caspase activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Caspase 9; Cytochromes c; Enzyme Activation; Humans; Jurkat Cells; Mice; Mice, Knockout; Mitochondria; Protein Multimerization; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis.
Topics: Base Sequence; Chromatin Immunoprecipitation; Core Binding Factor Alpha 1 Subunit; DNA Primers; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Mesenchymal Stem Cells; Osteogenesis; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Estrogen; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation | 2011 |
Enhancing the bioavailability of resveratrol by combining it with piperine.
Topics: Alkaloids; Animals; Benzodioxoles; Biological Availability; Drug Interactions; Glucuronides; Mice; Mice, Inbred C57BL; Piperidines; Polyunsaturated Alkamides; Resveratrol; Stilbenes | 2011 |
Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Aromatase Inhibitors; Caco-2 Cells; Cyclooxygenase Inhibitors; Humans; Mice; NF-kappa B; Quinone Reductases; Rats; Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Resveratrol and prostate cancer: promising role for microRNAs.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Male; MicroRNAs; Prostatic Neoplasms; PTEN Phosphohydrolase; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes | 2011 |
Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat.
Topics: Adipose Tissue; Animals; Biological Availability; Biomarkers; Body Temperature Regulation; Bone Density; Enzyme Inhibitors; Glucose Tolerance Test; Hindlimb Suspension; Inflammation; Insulin Resistance; Male; Muscle, Skeletal; Muscular Atrophy; Physical Conditioning, Animal; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2011 |
Aloe vera or resveratrol supplementation in larval diet delays adult aging in the fruit fly, Drosophila melanogaster.
Topics: Aging; Aloe; Animals; Body Weight; Catalase; Drosophila melanogaster; Female; Fertility; Larva; Lipids; Longevity; Motor Activity; Resveratrol; Stilbenes; Superoxide Dismutase | 2011 |
Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.
Topics: Apoptosis; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA-Binding Proteins; DNA, Neoplasm; Drug Screening Assays, Antitumor; Endoplasmic Reticulum; Endoribonucleases; Gene Expression Regulation, Neoplastic; Humans; Multiple Myeloma; Neoplasm Proteins; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Regulatory Factor X Transcription Factors; Resveratrol; RNA Splicing; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors; Transcription, Genetic; Unfolded Protein Response; X-Box Binding Protein 1 | 2011 |
Structure and function of the oxidation products of polyphenols and identification of potent lipoxygenase inhibitors from Fe-catalyzed oxidation of resveratrol.
Topics: Antioxidants; Iron; Lipoxygenase Inhibitors; Molecular Structure; Oxidation-Reduction; Polyphenols; Resveratrol; Stilbenes | 2011 |
High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression.
Topics: Animals; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Female; Glycated Hemoglobin; Hep G2 Cells; Humans; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Triglycerides | 2011 |
Resveratrol inhibits migration and Rac1 activation in EGF- but not PDGF-activated vascular smooth muscle cells.
Topics: Androstadienes; Animals; Cell Movement; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Pseudopodia; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wortmannin | 2011 |
Detection of ochratoxin A and cis- and trans-resveratrol in red wines and their musts from Calabria (Italy).
Topics: Chromatography, High Pressure Liquid; Italy; Ochratoxins; Resveratrol; Solid Phase Extraction; Stereoisomerism; Stilbenes; Vitis; Wine | 2011 |
Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress.
Topics: Acyl-CoA Oxidase; Animals; Antioxidants; Carnitine O-Palmitoyltransferase; Dose-Response Relationship, Drug; Fatty Acids; Fatty Liver; Isoenzymes; Lipid Metabolism; Lipids; Liver; Male; Obesity; Organ Size; Oxidative Stress; Random Allocation; Rats; Rats, Zucker; Resveratrol; Stilbenes; Up-Regulation | 2012 |
Resveratrol inhibits Cdk5 activity through regulation of p35 expression.
Topics: Animals; Cells, Cultured; Cyclin-Dependent Kinase 5; Early Growth Response Protein 1; Ganglia, Spinal; Gene Expression Regulation; Luciferases; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Neurons; NF-kappa B; PC12 Cells; Phosphotransferases; Promoter Regions, Genetic; Protein Kinase Inhibitors; Rats; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol, through NF-Y/p53/Sin3/HDAC1 complex phosphorylation, inhibits estrogen receptor alpha gene expression via p38MAPK/CK2 signaling in human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Casein Kinase II; CCAAT-Binding Factor; Cell Line, Tumor; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; p38 Mitogen-Activated Protein Kinases; Resveratrol; Sin3 Histone Deacetylase and Corepressor Complex; Stilbenes; Tumor Suppressor Protein p53 | 2011 |
Greater effectiveness of ε-viniferin in red wine than its monomer resveratrol for inhibiting vascular smooth muscle cell proliferation and migration.
Topics: Animals; Atherosclerosis; Benzofurans; Cell Movement; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Wine | 2011 |
Resveratrol, an effective regulator of ovarian development and oocyte apoptosis.
Topics: Animals; Animals, Newborn; Apoptosis; Female; Male; Oocytes; Ovary; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2011 |
Antiproliferation and redifferentiation in thyroid cancer cell lines by polyphenol phytochemicals.
Topics: Antigens, CD; Antineoplastic Agents; Carcinoma, Embryonal; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Flavonoids; Gene Expression Regulation, Neoplastic; Genistein; Humans; Kaempferols; Models, Biological; Phenols; Polyphenols; Quercetin; Receptors, G-Protein-Coupled; Resorcinols; Resveratrol; Stilbenes; Symporters; Thyroid Neoplasms | 2011 |
Resveratrol acts not through anti-aggregative pathways but mainly via its scavenging properties against Aβ and Aβ-metal complexes toxicity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Coordination Complexes; Humans; Neuroblastoma; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Improving glucose metabolism with resveratrol in a swine model of metabolic syndrome through alteration of signaling pathways in the liver and skeletal muscle.
Topics: Animals; Blood Glucose; Case-Control Studies; Dietary Carbohydrates; Energy Intake; Energy Metabolism; Insulin; Insulin Resistance; Liver; Liver Function Tests; Metabolic Syndrome; Microscopy, Fluorescence; Muscle, Skeletal; Phytotherapy; Plant Extracts; Resveratrol; Signal Transduction; Stilbenes; Swine; Swine, Miniature; Treatment Outcome | 2011 |
Resveratrol induces apoptosis in pancreatic cancer cells.
Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Survival; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2011 |
Notch-1 activation-dependent p53 restoration contributes to resveratrol-induced apoptosis in glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Genes, p53; Glioblastoma; Humans; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor, Notch1; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2011 |
Challenges of translating basic research into therapeutics: resveratrol as an example.
Topics: Aging; Animals; Antioxidants; Biological Availability; Clinical Trials as Topic; Humans; Resveratrol; Stilbenes; Translational Research, Biomedical | 2012 |
Role of 5-lipoxygenase in resveratrol mediated suppression of 7,12-dimethylbenz(α)anthracene-induced mammary carcinogenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Proliferation; Cyclin D1; DNA Breaks; Female; Gene Expression Regulation, Neoplastic; In Situ Nick-End Labeling; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Mammary Glands, Animal; Mammary Neoplasms, Experimental; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2011 |
Effects of elicitors on the production of resveratrol and viniferins in cell cultures of Vitis vinifera L. cv Italia.
Topics: Acetates; Benzofurans; Cells, Cultured; Chitosan; Cyclopentanes; Oxylipins; Plant Growth Regulators; Plant Stems; Resorcinols; Resveratrol; Stilbenes; Vitis | 2011 |
Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis.
Topics: Animals; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Cell Line; Chemokine CCL2; Chemotaxis, Leukocyte; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Humans; Hyperlipidemias; Kidney; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Oxidative Stress; Receptors, CCR2; Receptors, LDL; Resveratrol; Stilbenes; Time Factors; Triterpenes; Ursolic Acid | 2011 |
Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect.
Topics: Anti-Inflammatory Agents; Antifungal Agents; Antioxidants; Benzo(a)pyrene; Cell Survival; Cells, Cultured; Humans; Interleukin-8; Keratinocytes; Ketoconazole; Naphthalenes; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Terbinafine; Tumor Necrosis Factor-alpha | 2012 |
Resveratrol prevents norepinephrine induced hypertrophy in adult rat cardiomyocytes, by activating NO-AMPK pathway.
Topics: Adenylate Kinase; Animals; Cell Size; Hypertrophy; Male; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Niacinamide; Nitric Oxide; Norepinephrine; Protein Biosynthesis; Pyrazoles; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Resveratrol; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Stilbenes | 2011 |
Resveratrol oligomers isolated from Carex species inhibit growth of human colon tumorigenic cells mediated by cell cycle arrest.
Topics: Caco-2 Cells; Carex Plant; Cell Cycle Checkpoints; Cell Division; Colon; Colonic Neoplasms; HCT116 Cells; HT29 Cells; Humans; Resveratrol; Stilbenes | 2011 |
Resveratrol ameliorates TNFα-mediated suppression of erythropoiesis in human CD34(+) cells via modulation of NF-κB signalling.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD34; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythroid Precursor Cells; Erythroid-Specific DNA-Binding Factors; Erythropoiesis; Humans; Middle Aged; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Role of Akt-dependent pathway in resveratrol-mediated cardioprotection after trauma-hemorrhage.
Topics: Androstadienes; Animals; Apoptosis; Cardiac Output; Cardiotonic Agents; Heart; Hemorrhage; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Models, Animal; Myocardium; Peroxidase; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Ventricular Function, Left; Wortmannin; Wounds and Injuries | 2012 |
Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease.
Topics: alpha-Synuclein; AMP-Activated Protein Kinases; Animals; Antioxidants; Autophagy; Cell Line, Transformed; Dose-Response Relationship, Drug; Doxycycline; Gene Expression Regulation; Humans; Insecticides; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Mutation; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Rats; Resveratrol; RNA, Small Interfering; Rotenone; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors | 2011 |
Resveratrol may be an effective prophylactic agent for ischemic stroke.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Brain Ischemia; Coronary Disease; Cyclooxygenase Inhibitors; Free Radical Scavengers; Humans; Neuroprotective Agents; Nitric Oxide; Resveratrol; Stilbenes; Stroke; Wine | 2011 |
Resveratrol supplementation abrogates pro-arteriogenic effects of intramyocardial vascular endothelial growth factor in a hypercholesterolemic swine model of chronic ischemia.
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Coronary Angiography; Coronary Circulation; Disease Models, Animal; Drug Therapy, Combination; Hypercholesterolemia; Immunoblotting; Immunohistochemistry; Male; Myocardial Ischemia; Neovascularization, Physiologic; Oxidative Stress; Phosphorylation; Random Allocation; Reference Values; Resveratrol; Risk Factors; Sensitivity and Specificity; Stilbenes; Swine; Vascular Endothelial Growth Factor A | 2011 |
Repeated and long-term treatment with physiological concentrations of resveratrol promotes NO production in vascular endothelial cells.
Topics: Antioxidants; Cardiovascular Diseases; Cells, Cultured; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Estrogen Antagonists; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Osmolar Concentration; Phosphorylation; PPAR alpha; Protein Processing, Post-Translational; Resveratrol; RNA, Messenger; Stilbenes; Time Factors; Up-Regulation; Wine | 2012 |
Resveratrol ameliorates metabolic disorders and muscle wasting in streptozotocin-induced diabetic rats.
Topics: Adenylate Kinase; Animals; Antioxidants; Cytokines; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Male; Metabolic Diseases; Models, Biological; Muscle, Skeletal; Muscular Diseases; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Streptozocin; Wasting Syndrome | 2011 |
Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocysts.
Topics: Animals; Antioxidants; Apoptosis; Blastocyst; Caspase 3; Cell Proliferation; Embryonic Development; Enzyme Activation; Female; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Pregnancy; Pyruvaldehyde; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits the epidermal growth factor-induced epithelial mesenchymal transition in MCF-7 cells.
Topics: Actin Depolymerizing Factors; Angiogenesis Inhibitors; Breast Neoplasms; Butadienes; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Shape; Cell Survival; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Immunoblotting; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phosphorylation; Repressor Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Stilbenes; Transcription Factors; Vimentin; Zinc Finger E-box Binding Homeobox 2; Zinc Finger E-box-Binding Homeobox 1 | 2011 |
Comparative effects of retinoic acid, vitamin D and resveratrol alone and in combination with adenosine analogues on methylation and expression of phosphatase and tensin homologue tumour suppressor gene in breast cancer cells.
Topics: Adenocarcinoma; Adenosine; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cholecalciferol; Cyclin-Dependent Kinase Inhibitor p21; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Neoplasm Proteins; Promoter Regions, Genetic; PTEN Phosphohydrolase; Resveratrol; RNA, Messenger; Stilbenes; Tretinoin; Vitamins | 2012 |
Synthesis and antimicrobial activity of (E) stilbene derivatives.
Topics: Animals; Anti-Infective Agents; Cell Line; Disk Diffusion Antimicrobial Tests; Mice; Resveratrol; Stereoisomerism; Stilbenes | 2011 |
New method for determination of (E)-resveratrol in wine based on microextraction using packed sorbent and ultra-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Resveratrol; Solid Phase Microextraction; Stereoisomerism; Stilbenes; Wine | 2011 |
Role of resveratrol-induced CD11b(+) Gr-1(+) myeloid derived suppressor cells (MDSCs) in the reduction of CXCR3(+) T cells and amelioration of chronic colitis in IL-10(-/-) mice.
Topics: Animals; CD11b Antigen; Cell Proliferation; Cell Separation; Chronic Disease; Colitis; Cytokines; Disease Progression; Enzyme-Linked Immunosorbent Assay; Feces; Flow Cytometry; Immunoglobulin A; Immunoglobulin G; Interleukin-10; Mice; Mice, Knockout; Mucous Membrane; Myeloid Cells; Receptors, Chemokine; Receptors, CXCR3; Resveratrol; Serum Amyloid A Protein; Spleen; Stilbenes; T-Lymphocytes; Weight Loss | 2012 |
[Resveratrol derived from rhizoma et radix polygoni cuspidati and its liposomal form protect nigral cells of Parkinsonian rats].
Topics: Animals; Antioxidants; Behavior; Cell Death; Disease Models, Animal; Drugs, Chinese Herbal; Liposomes; Neurons; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes; Substantia Nigra | 2011 |
Roles of SIRT1 in high glucose-induced endothelial impairment: association with diabetic atherosclerosis.
Topics: Atherosclerosis; Base Sequence; Cells, Cultured; Diabetic Angiopathies; DNA Primers; Endothelium, Vascular; Glucose; Humans; Nitric Oxide; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2011 |
Continued postnatal administration of resveratrol prevents diet-induced metabolic syndrome in rat offspring born growth restricted.
Topics: Animals; Antioxidants; Body Weight; Calorimetry, Indirect; Dietary Fats; Energy Intake; Female; Fetal Growth Retardation; Hypoxia; Insulin Resistance; Male; Metabolic Syndrome; Motor Activity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Resveratrol; Stilbenes | 2011 |
Resveratrol inhibition of inducible nitric oxide synthase in skeletal muscle involves AMPK but not SIRT1.
Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Animals; Cells, Cultured; Drug Evaluation, Preclinical; Enzyme Inhibitors; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Nitric Oxide Synthase Type II; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2011 |
Resveratrol--current status and outlook.
Topics: Animals; Humans; Periodicals as Topic; Resveratrol; Stilbenes | 2011 |
Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights.
Topics: Antioxidants; Cell Line; Diabetes Mellitus, Type 1; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Mitochondria; Monocytes; NADPH Oxidases; Oxidative Stress; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Superoxides; Up-Regulation | 2012 |
Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells.
Topics: Apoptosis; Atherosclerosis; Caspases; Cell Differentiation; Cells, Cultured; Diabetes Mellitus; Humans; Hypoglycemic Agents; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Resveratrol; Rosiglitazone; Signal Transduction; Stilbenes; Thiazolidinediones; Up-Regulation | 2011 |
Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.
Topics: Animals; Hepatocytes; Immunohistochemistry; Kupffer Cells; Lipids; Male; Mice; Mice, Transgenic; Mitochondria; Resveratrol; Stilbenes | 2011 |
Production of the phytoalexins trans-resveratrol and delta-viniferin in two economy-relevant grape cultivars upon infection with Botrytis cinerea in field conditions.
Topics: Benzofurans; Botrytis; Chromatography, High Pressure Liquid; Mass Spectrometry; Phenols; Phytoalexins; Resorcinols; Resveratrol; Sesquiterpenes; Species Specificity; Stilbenes; Vitis; Wine | 2012 |
Polyphenols in alcoholic beverages activating constitutive androstane receptor CAR.
Topics: Acyclic Monoterpenes; Alcohol Drinking; Alcoholic Beverages; Alkenes; Animals; Constitutive Androstane Receptor; Ellagic Acid; Energy Metabolism; Flavonoids; Genes, Reporter; Hep G2 Cells; Humans; Luciferases; Mice; Monoterpenes; Plasmids; Polycyclic Sesquiterpenes; Polyphenols; Propiophenones; Receptors, Cytoplasmic and Nuclear; Resveratrol; Risk Reduction Behavior; Sesquiterpenes; Stilbenes; Transfection | 2011 |
Resveratrol and vitamin D: significant potential interpretative problems arising from their mutual processes, interactions and effects.
Topics: Drug Interactions; Humans; Models, Theoretical; Resveratrol; Stilbenes; Vitamin D | 2011 |
Over-expression of a grape stilbene synthase gene in tomato induces parthenocarpy and causes abnormal pollen development.
Topics: Acyltransferases; Agrobacterium; Biosynthetic Pathways; Flavanones; Genes, Plant; Germination; Microscopy, Confocal; Parthenogenesis; Plants, Genetically Modified; Pollen; Pollination; Resveratrol; RNA, Plant; Solanum lycopersicum; Stilbenes; Transformation, Genetic; Vitis | 2011 |
The effect of resveratrol on blood pressure in a rat model of preeclampsia.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Disease Models, Animal; Down-Regulation; Drug Evaluation, Preclinical; Female; Male; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Renal Circulation; Resveratrol; Stilbenes | 2012 |
Resveratrol pretreatment attenuates cerebral ischemic injury by upregulating expression of transcription factor Nrf2 and HO-1 in rats.
Topics: Animals; Antioxidants; Brain Ischemia; Caspase 3; DNA Fragmentation; Down-Regulation; Heme Oxygenase-1; Infarction, Middle Cerebral Artery; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Up-Regulation | 2011 |
Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents.
Topics: Antimitotic Agents; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Nucleus; Drug Design; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Microtubules; Models, Molecular; Nitro Compounds; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tubulin Modulators; Vinyl Compounds | 2011 |
Application of liposome encapsulation technique to improve anti-carcinoma effect of resveratrol.
Topics: Anticarcinogenic Agents; Biological Availability; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Liposomes; Particle Size; Polyethylene Glycols; Resveratrol; Solubility; Stilbenes; Surface Properties; Tumor Cells, Cultured | 2012 |
Effects of long-term consumption of low doses of resveratrol on diet-induced mild hypercholesterolemia in pigs: a transcriptomic approach to disease prevention.
Topics: Animals; Atherosclerosis; Cholesterol; Diet, High-Fat; Dietary Fats; Dose-Response Relationship, Drug; Down-Regulation; Fatty Acid-Binding Proteins; Female; Hypercholesterolemia; Leukocytes, Mononuclear; Lipid Metabolism; Lipoprotein Lipase; Lipoproteins, LDL; Male; Microarray Analysis; Resveratrol; Stilbenes; Swine; Transcriptome; Up-Regulation | 2012 |
Dietary factors and lung function in the general population: wine and resveratrol intake.
Topics: Adult; Aged; Antioxidants; Cohort Studies; Feeding Behavior; Female; Forced Expiratory Volume; Genetic Predisposition to Disease; Humans; Lung; Male; Middle Aged; Polymorphism, Single Nucleotide; Pulmonary Disease, Chronic Obstructive; Resveratrol; Risk Factors; Sirtuin 1; Stilbenes; Vital Capacity; Wine | 2012 |
Mechanisms regulating enhanced human leukocyte antigen class II-mediated CD4 + T cell recognition of human B-cell lymphoma by resveratrol.
Topics: Antigen Presentation; Antineoplastic Agents, Phytogenic; Blotting, Western; Cathepsins; CD4-Positive T-Lymphocytes; Cell Proliferation; Endocytosis; Flow Cytometry; HLA-D Antigens; Humans; Lymphoma, B-Cell; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2012 |
Anti-tumor and immunomodulatory activity of resveratrol in vitro and its potential for combining with cancer immunotherapy.
Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Immunotherapy; Leukocytes, Mononuclear; Mice; Mice, Nude; Neoplasms; Resveratrol; Spleen; Stilbenes | 2011 |
Spectroscopic analysis on the resveratrol-DNA binding interactions at physiological pH.
Topics: Absorption; Animals; Cattle; DNA; Equipment Design; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Protein Binding; Resveratrol; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Stilbenes; Thermodynamics; Viscosity | 2011 |
Resveratrol inhibits proliferation and survival of Epstein Barr virus-infected Burkitt's lymphoma cells depending on viral latency program.
Topics: Apoptosis; Burkitt Lymphoma; Cell Cycle Checkpoints; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Epstein-Barr Virus Infections; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes; Viral Matrix Proteins; Virus Latency | 2011 |
Neuroendocrine regulation of autophagy by leptin.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Enzyme Activation; Female; HeLa Cells; Humans; Leptin; Liver; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Muscle, Skeletal; Plasmids; Receptors, Leptin; Recombinant Fusion Proteins; Resveratrol; Signal Transduction; Sirolimus; Spermidine; Stilbenes; Time Factors; TOR Serine-Threonine Kinases; Transfection | 2011 |
Chemistry of trans-resveratrol with singlet oxygen: [2+2] addition, [4+2] addition, and formation of the phytoalexin moracin M.
Topics: Benzofurans; Cyclization; Molecular Structure; Resorcinols; Resveratrol; Singlet Oxygen; Stereoisomerism; Stilbenes | 2011 |
[Effects of resveratrol on lipid metabolism in C57BL/6J mice].
Topics: Animals; Anticholesteremic Agents; Cholesterol; Dietary Fats; Hypercholesterolemia; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Triglycerides | 2011 |
Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Catalase; Diabetes Mellitus, Experimental; gamma-Glutamyltransferase; Kidney; Lipid Peroxidation; Liver; Male; Oxidative Stress; Porphobilinogen Synthase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Biosynthesis of the major tetrahydroxystilbenes in spruce, astringin and isorhapontin, proceeds via resveratrol and is enhanced by fungal infection.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Ascomycota; Coenzyme A Ligases; Conserved Sequence; Escherichia coli; Glucosides; Glycosylation; Host-Pathogen Interactions; Hydroxylation; Malonyl Coenzyme A; Methylation; Molecular Sequence Data; Phylogeny; Picea; Plant Diseases; Plant Proteins; Plants, Genetically Modified; Resveratrol; Stilbenes | 2011 |
Resveratrol potentiates the cytotoxic oxidative stress induced by chemotherapy in human colon cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Fluorouracil; Humans; Lipid Peroxidation; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2011 |
LongSAGE gene-expression profiling of Botrytis cinerea germination suppressed by resveratrol, the major grapevine phytoalexin.
Topics: Botrytis; Down-Regulation; Fungal Proteins; Gene Expression Profiling; Gene Expression Regulation, Fungal; Phytoalexins; Plant Diseases; Plant Extracts; Resveratrol; Sesquiterpenes; Spores, Fungal; Stilbenes; Vitis | 2011 |
Resveratrol inhibits monocytic cell chemotaxis to MCP-1 and prevents spontaneous endothelial cell migration through Rho kinase-dependent mechanism.
Topics: Blotting, Western; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Monocytes; Phosphorylation; Resveratrol; rho-Associated Kinases; Stilbenes | 2011 |
Chemical modifications of resveratrol for improved protein kinase C alpha activity.
Topics: Binding Sites; Cell Survival; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Molecular Structure; Protein Kinase C-alpha; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2011 |
Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Protein Stability; Remission Induction; Resveratrol; Skin Neoplasms; Stilbenes; Tea; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
Resveratrol alters microRNA expression profiles in A549 human non-small cell lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; MicroRNAs; Oligonucleotide Array Sequence Analysis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Resveratrol attenuates apoptosis of pulmonary microvascular endothelial cells induced by high shear stress and proinflammatory factors.
Topics: Antioxidants; Apoptosis; Biomechanical Phenomena; Cell Proliferation; Cells, Cultured; Cycloheximide; Endothelial Cells; Humans; Inflammation Mediators; Lung; Reactive Oxygen Species; Resveratrol; Shear Strength; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Annexin A5; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Antibody Technique; Humans; Mitochondria; Motor Neurons; Mutation; Neuroprotective Agents; Niacinamide; Propidium; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tetrazolium Salts; Thiazoles; Up-Regulation | 2011 |
Formation of diethylstilbestrol-DNA adducts in human breast epithelial cells and inhibition by resveratrol.
Topics: Cell Line, Tumor; Chromatography, High Pressure Liquid; Diethylstilbestrol; DNA Adducts; Electrochemistry; Female; Humans; Mammary Glands, Human; Resveratrol; Stilbenes | 2011 |
Mediobasal hypothalamic SIRT1 is essential for resveratrol's effects on insulin action in rats.
Topics: Animals; Enzyme Activators; Enzyme Inhibitors; Gene Silencing; Glucose; Hypoglycemic Agents; Hypothalamus, Middle; Insulin; Insulin Antagonists; Insulin Resistance; KATP Channels; Liver; Male; Organ Specificity; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2011 |
In planta production of the highly potent resveratrol analogue pterostilbene via stilbene synthase and O-methyltransferase co-expression.
Topics: Acyltransferases; Arabidopsis; Arachis; Chromatography, High Pressure Liquid; Enzyme Activation; Enzyme Assays; Flavonoids; Flowers; Gene Expression Regulation, Enzymologic; Genetic Vectors; Metabolic Engineering; Methylation; Models, Molecular; Nicotiana; Phenotype; Pigmentation; Plant Proteins; Plants, Genetically Modified; Protein O-Methyltransferase; Recombinant Proteins; Resveratrol; Sorghum; Stilbenes; Substrate Specificity; Transformation, Genetic | 2012 |
Thermodynamic analysis of protein-ligand interactions in complex biological mixtures using a shotgun proteomics approach.
Topics: Algorithms; Amino Acid Sequence; Antioxidants; Glutamate Dehydrogenase; Hydrogen Peroxide; Methionine; Molecular Sequence Data; NAD; Oxidants; Oxidation-Reduction; Peptide Fragments; Protein Binding; Proteome; Resveratrol; Saccharomyces cerevisiae Proteins; Stilbenes; Tandem Mass Spectrometry; Thermodynamics | 2011 |
Effect of resveratrol derivative BTM-0512 on high glucose-induced dysfunction of endothelial cells: role of SIRT1.
Topics: Antioxidants; Cell Adhesion; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Humans; Neovascularization, Physiologic; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells.
Topics: Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Cholesterol; DNA Replication; Dose-Response Relationship, Drug; Drug Synergism; Female; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Polyisoprenyl Phosphates; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Simvastatin; Stilbenes; Theca Cells | 2011 |
The genoprotective activity of resveratrol on aflatoxin B₁-induced DNA damage in human lymphocytes in vitro.
Topics: Aflatoxin B1; Antioxidants; Chromosome Aberrations; DNA Damage; Humans; Lymphocytes; Male; Mutagenicity Tests; Resveratrol; Sister Chromatid Exchange; Stilbenes | 2012 |
The spatial association of gene expression evolves from synchrony to asynchrony and stochasticity with age.
Topics: Aging; Animals; Caloric Restriction; Female; Male; Mice; Rats; Resveratrol; Stilbenes; Stochastic Processes; Time Factors; Transcriptome | 2011 |
Aza-derivatives of resveratrol are potent macrophage migration inhibitory factor inhibitors.
Topics: Amino Acid Sequence; Aza Compounds; Cell Line, Tumor; Cell Proliferation; Female; Humans; Macrophage Migration-Inhibitory Factors; MCF-7 Cells; Molecular Sequence Data; Resveratrol; Stilbenes | 2012 |
Resveratrol blocks diabetes-induced early vascular lesions and vascular endothelial growth factor induction in mouse retinas.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood Glucose; Blood-Retinal Barrier; Blotting, Western; Body Weight; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred C57BL; Pericytes; Resveratrol; Retina; Retinal Vessels; Stilbenes; Vascular Endothelial Growth Factor A | 2012 |
Resveratrol attenuates acute hypoxic injury in cardiomyocytes: correlation with inhibition of iNOS-NO signaling pathway.
Topics: Animals; Animals, Newborn; Cardiotonic Agents; Cell Culture Techniques; Cell Hypoxia; Cell Survival; Cells, Cultured; Culture Media; Lactate Dehydrogenases; Male; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology.
Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Blotting, Western; Cell Line; Cell Nucleus; Cytoplasm; Enzyme Activators; Fluorescent Antibody Technique; Humans; Microscopy, Confocal; Phenformin; Phosphorylation; Resveratrol; Ribonucleotides; Stilbenes | 2011 |
Enhanced extracellular production of trans-resveratrol in Vitis vinifera suspension cultured cells by using cyclodextrins and methyljasmonate.
Topics: Acetates; Biotechnology; Cell Culture Techniques; Cells, Cultured; Culture Media; Cyclodextrins; Cyclopentanes; Dose-Response Relationship, Drug; Extracellular Space; Oxylipins; Resveratrol; Stilbenes; Sucrose; Ultraviolet Rays; Vitis | 2012 |
Effect and mechanism of action of resveratrol: a novel melanolytic compound from the peanut skin of Arachis hypogaea.
Topics: Adrenergic Antagonists; Animals; Arachis; Bufonidae; Cholinergic Agonists; Dose-Response Relationship, Drug; Melanophores; Pigmentation; Plant Extracts; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Resveratrol; Stilbenes; Tail | 2011 |
Resveratrol suppresses constitutive activation of AKT via generation of ROS and induces apoptosis in diffuse large B cell lymphoma cell lines.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytochromes c; Humans; Immunoblotting; Lymphoma, Large B-Cell, Diffuse; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2011 |
Cloning a peanut resveratrol synthase gene and its expression in purple sweet potato.
Topics: Acyltransferases; Agrobacterium; Arachis; Cloning, Molecular; Culture Media; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Ipomoea batatas; Kanamycin; Plant Roots; Plants, Genetically Modified; Resveratrol; Sequence Analysis; Stilbenes; Transformation, Genetic | 2012 |
Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract suppresses multiple angiogenesis-related endothelial cell functions and tumor angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Biological Assay; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Discovery; Female; Glucosides; Gnetum; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred ICR; Neovascularization, Pathologic; Plant Extracts; Resveratrol; Seeds; Stilbenes | 2011 |
5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.
Topics: Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Movement; Cell Survival; Colorectal Neoplasms; DNA Damage; Fluorouracil; HCT116 Cells; Humans; MAP Kinase Signaling System; Resveratrol; Stilbenes | 2011 |
Increased susceptibility to resveratrol of Helicobacter pylori strains isolated from patients with gastric carcinoma.
Topics: Adult; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Proteins; Female; Helicobacter Infections; Helicobacter pylori; Humans; Proton-Translocating ATPases; Resveratrol; Stilbenes; Stomach Neoplasms | 2011 |
Inhibitory effects of resveratrol and pterostilbene on human colon cancer cells: a side-by-side comparison.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Survival; Colonic Neoplasms; HCT116 Cells; HT29 Cells; Humans; Resveratrol; Stilbenes | 2011 |
Resveratrol-mediated gamma interferon reduction prevents airway inflammation and airway hyperresponsiveness in respiratory syncytial virus-infected immunocompromised mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Female; Gene Expression Profiling; Inflammation; Interferon-gamma; Lung; Mice; Mice, Inbred BALB C; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 3; Viral Load | 2011 |
Resveratrol content and expression of phenylalanine ammonia-lyase and stilbene synthase genes in cell cultures of Vitis amurensis treated with coumaric acid.
Topics: Acyltransferases; Cell Culture Techniques; Cells, Cultured; Coumaric Acids; Gene Expression Regulation, Plant; Phenylalanine Ammonia-Lyase; Plant Proteins; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis | 2011 |
Subchronic oral toxicity and cardiovascular safety pharmacology studies of resveratrol, a naturally occurring polyphenol with cancer preventive activity.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Kidney; Male; No-Observed-Adverse-Effect Level; Organ Size; Polyphenols; Rats; Resveratrol; Stilbenes; Toxicity Tests, Subchronic; Urinary Bladder | 2011 |
Resveratrol modulates MED28 (Magicin/EG-1) expression and inhibits epidermal growth factor (EGF)-induced migration in MDA-MB-231 human breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulation; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Mediator Complex; Plant Extracts; Resveratrol; Stilbenes | 2011 |
Structural revision and total synthesis of caraphenol B and C.
Topics: Crystallography, X-Ray; Molecular Structure; Phenols; Resveratrol; Stereoisomerism; Stilbenes | 2011 |
Resveratrol improves insulin signaling in a tissue-specific manner under insulin-resistant conditions only: in vitro and in vivo experiments in rodents.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Culture Media, Conditioned; Dietary Fats; Inflammation; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Protective potential of resveratrol against oxidative stress and apoptosis in Batten disease lymphoblast cells.
Topics: Apoptosis; Biomarkers; Cells, Cultured; Cytoprotection; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Neuronal Ceroid-Lipofuscinoses; Neuroprotective Agents; Oxidative Stress; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2011 |
Prevention and treatment of Schistosoma mansoni-induced liver fibrosis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Bilirubin; Curcumin; Hydroxyproline; Imatinib Mesylate; Liver; Liver Cirrhosis; Male; Mice; Piperazines; Pyrimidines; Resveratrol; Schistosoma mansoni; Schistosomiasis mansoni; Serum Albumin; Stilbenes | 2011 |
Resveratrol ameliorates oxidative DNA damage and protects against acrylamide-induced oxidative stress in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acrylamide; Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatinine; Cytokines; Deoxyguanosine; DNA Damage; Female; Glutathione; Humans; L-Lactate Dehydrogenase; Lymphocytes; Male; Malondialdehyde; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Synergistic effect of resveratrol and quercetin released from drug-eluting polymer coatings for endovascular devices.
Topics: Antioxidants; Blood Platelets; Cell Proliferation; Diffusion; Drug Synergism; Drug-Eluting Stents; Humans; Inflammation; Kinetics; Macrophages; Muscle, Smooth, Vascular; Nanocomposites; Platelet Activation; Polymers; Quercetin; Resveratrol; Stents; Stilbenes; Vasodilator Agents | 2011 |
Resveratrol modulates murine collagen-induced arthritis by inhibiting Th17 and B-cell function.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Autoantibodies; B-Lymphocytes; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunosuppressive Agents; Inflammation Mediators; Male; Mice; Mice, Inbred DBA; Resveratrol; Stilbenes; Th17 Cells | 2012 |
Resveratrol protects against 2-bromopropane-induced apoptosis and disruption of embryonic development in blastocysts.
Topics: Animals; Antioxidants; Apoptosis; Blastocyst; Cell Proliferation; Cell Survival; Dietary Supplements; Dose-Response Relationship, Drug; Embryo Implantation; Embryonic Development; Female; Hydrocarbons, Brominated; Mice; Pregnancy; Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2011 |
Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice.
Topics: Adipocytes; Adiponectin; Animals; Azoxymethane; Caco-2 Cells; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dextran Sulfate; Dietary Fats; Dose-Response Relationship, Drug; Female; Humans; Insulin; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Resveratrol; Sex Factors; Stilbenes; Weight Gain | 2011 |
Resveratrol counteracts systemic and local inflammation involved in early abdominal aortic aneurysm development.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aortic Aneurysm, Abdominal; Disease Models, Animal; Disease Progression; L-Selectin; Macrophages, Peritoneal; Male; Matrix Metalloproteinase 9; Monocytes; Pancreatic Elastase; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vasculitis | 2011 |
Combination of resveratrol and antiandrogen flutamide has synergistic effect on androgen receptor inhibition in prostate cancer cells.
Topics: Androgen Antagonists; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cycloheximide; Dihydrotestosterone; Down-Regulation; Drug Synergism; Flutamide; Gene Expression Regulation, Neoplastic; Humans; Male; Prostate-Specific Antigen; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Receptors, Androgen; Resveratrol; RNA, Messenger; Stilbenes; Transcriptional Activation | 2011 |
Phenolic composition of Tempranillo wines following early defoliation of the vines.
Topics: Agriculture; Anthocyanins; Chromatography, High Pressure Liquid; Coumaric Acids; Ethanol; Fermentation; Flavonols; Food Handling; Fruit; Glycosides; Phenols; Pigments, Biological; Quality Control; Resveratrol; Saccharomyces cerevisiae; Spain; Stilbenes; Vitis; Wine | 2012 |
Interaction between resveratrol and thrombin and its biological implication.
Topics: Animals; Apoptosis; Blood Platelets; Cattle; Fluorescence; Functional Food; Hydrogen; Hydrophobic and Hydrophilic Interactions; Isomerism; Kinetics; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Conformation; Resveratrol; Stilbenes; Thrombin | 2011 |
Natural prenylated resveratrol analogs arachidin-1 and -3 demonstrate improved glucuronidation profiles and have affinity for cannabinoid receptors.
Topics: Animals; Binding, Competitive; Biological Availability; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Glucuronosyltransferase; Hemiterpenes; Humans; Kinetics; Mass Spectrometry; Metabolic Detoxication, Phase II; Models, Molecular; Prenylation; Receptors, Cannabinoid; Recombinant Proteins; Resveratrol; Stilbenes | 2012 |
3,4,4'-Trihydroxy-trans-stilbene, an analogue of resveratrol, is a potent antioxidant and cytotoxic agent.
Topics: Anisoles; Antineoplastic Agents; Antioxidants; Cell Proliferation; DNA Damage; Free Radicals; Hemolysis; HL-60 Cells; Humans; Kinetics; Linoleic Acid; Lipid Peroxidation; Molecular Structure; Oxidative Stress; Resveratrol; Stilbenes; Structure-Activity Relationship | 2011 |
Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Epithelium; Glomerular Filtration Rate; Heart Rate; Kidney; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Microcirculation; Reactive Nitrogen Species; Resveratrol; Sepsis; Stilbenes; Survival Analysis; Time Factors; Vasodilator Agents | 2012 |
Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.
Topics: Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Forkhead Transcription Factors; Humans; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2011 |
Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Analysis of Variance; Animals; Biological Availability; Brain; Dietary Supplements; Disease Models, Animal; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Maze Learning; Mice; Neurotransmitter Agents; NF-kappaB-Inducing Kinase; Phosphorylation; PPAR alpha; Protein Serine-Threonine Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; tau Proteins | 2012 |
Differences in the in vitro susceptibility to resveratrol and other chemical compounds among several Philasterides dicentrarchi isolates from turbot.
Topics: Animals; Aquaculture; Ciliophora Infections; Cross Protection; Fish Diseases; Flatfishes; Formaldehyde; Hydrogen Peroxide; Oligohymenophorea; Resveratrol; Stilbenes | 2012 |
Resveratrol enhances the cytotoxic profile of docetaxel and doxorubicin in solid tumour cell lines in vitro.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-2-Associated X Protein; Cell Proliferation; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2011 |
Resveratrol mobilizes Ca2+ from intracellular stores and induces c-Jun N-terminal kinase activation in tumoral AR42J cells.
Topics: Animals; Antioxidants; Calcium; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Pancreatic Neoplasms; Rats; Resveratrol; Sincalide; Stilbenes; Thapsigargin | 2012 |
Resveratrol regulates antioxidant status, inhibits cytokine expression and restricts apoptosis in carbon tetrachloride induced rat hepatic injury.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Regulation; Immunohistochemistry; Interleukin-6; Lipid Peroxidation; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol protects against hyperglycemia-induced oxidative damage to mitochondria by activating SIRT1 in rat mesangial cells.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Glucose; Hyperglycemia; Mesangial Cells; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Superoxides; Time Factors | 2012 |
MicroRNA-622 functions as a tumor suppressor by targeting K-Ras and enhancing the anticarcinogenic effect of resveratrol.
Topics: Animals; Anticarcinogenic Agents; Bronchi; Cell Proliferation; Cells, Cultured; Genes, Tumor Suppressor; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; MicroRNAs; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Resveratrol; Stilbenes | 2012 |
Novel stably transfected gene reporter human hepatoma cell line for assessment of aryl hydrocarbon receptor transcriptional activity: construction and characterization.
Topics: Anthracenes; Gene Expression; Hep G2 Cells; Humans; Indoles; Luciferases; Methylcholanthrene; Omeprazole; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Transfection | 2011 |
Resveratrol inhibits cell differentiation in 3T3-L1 adipocytes via activation of AMPK.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; CCAAT-Enhancer-Binding Protein-alpha; Cell Differentiation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Lipogenesis; Mice; Obesity; Phosphorylation; PPAR gamma; Resveratrol; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2011 |
Resveratrol ameliorates hypoxia/ischemia-induced behavioral deficits and brain injury in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Brain Injuries; Female; Hypoxia-Ischemia, Brain; Male; Maze Learning; Memory; Neuroprotective Agents; Rats; Rats, Wistar; Reflex, Righting; Resveratrol; Stilbenes | 2011 |
High-throughput library screening identifies two novel NQO1 inducers in human lung cells.
Topics: Anticarcinogenic Agents; Antioxidants; Benzophenones; Blotting, Western; Bronchi; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Epithelial Cells; Glutathione; Glutathione S-Transferase pi; High-Throughput Screening Assays; Humans; NAD(P)H Dehydrogenase (Quinone); Polymerase Chain Reaction; Reactive Oxygen Species; Reproducibility of Results; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency.
Topics: Binding Sites; Biocatalysis; Biosynthetic Pathways; DNA; DNA-Binding Proteins; Enzymes; Escherichia coli; Metabolic Engineering; Mevalonic Acid; Plasmids; Propylene Glycol; Resveratrol; Stilbenes; Zinc Fingers | 2012 |
Antifungal activity of resveratrol against Botrytis cinerea is improved using 2-furyl derivatives.
Topics: Antifungal Agents; Botrytis; Cell Membrane; Cytoplasm; Electron Transport; Furans; Laccase; Microbial Sensitivity Tests; Mycelium; Oxygen Consumption; Resveratrol; Spores, Fungal; Stilbenes | 2011 |
The effects of resveratrol and selected metabolites on the radiation and antioxidant response.
Topics: Animals; Antioxidants; Cell Cycle; Cell Survival; Dose-Response Relationship, Drug; Edetic Acid; Female; Fibroblasts; Humans; Hydrogen Peroxide; Mice; Mice, Inbred C3H; Oxidative Stress; Phenols; Quinones; Radiation-Protective Agents; Resveratrol; Stilbenes; tert-Butylhydroperoxide; Whole-Body Irradiation | 2011 |
Evaluation of the stability and antioxidant activity of nanoencapsulated resveratrol during in vitro digestion.
Topics: Antioxidants; Caco-2 Cells; Capsules; Chemistry, Pharmaceutical; Digestion; Drug Stability; Emulsions; Humans; In Vitro Techniques; Nanotechnology; Resveratrol; Stilbenes | 2011 |
Resveratrol improves survival, hemodynamics and energetics in a rat model of hypertension leading to heart failure.
Topics: Animals; Body Weight; Disease Models, Animal; Endothelium, Vascular; Energy Metabolism; Heart; Heart Failure; Hemodynamics; Hypertension; Male; Mitochondria; Rats; Rats, Inbred Dahl; Resveratrol; Signal Transduction; Stilbenes; Survival Analysis | 2011 |
Resveratrol enhances prostate cancer cell response to ionizing radiation. Modulation of the AMPK, Akt and mTOR pathways.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; G1 Phase; Humans; Male; Microscopy, Fluorescence; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Radiation, Ionizing; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2011 |
Resveratrol abrogates adhesion molecules and protects against TNBS-induced ulcerative colitis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cell Adhesion Molecules; Colitis, Ulcerative; Colon; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Glutathione; Inflammation; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sulfasalazine; Trinitrobenzenesulfonic Acid; Vascular Cell Adhesion Molecule-1 | 2011 |
Natural polyphenols may ameliorate damage induced by copper overload.
Topics: Antioxidants; Caffeic Acids; Cell Line, Tumor; Copper; Curcumin; Enzyme Inhibitors; Humans; Polyphenols; Resveratrol; Stilbenes | 2012 |
Effects of resveratrol on HepG2 cells as revealed by (1)H-NMR based metabolic profiling.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Hep G2 Cells; Hepatocytes; Humans; Metabolome; Metabolomics; Multivariate Analysis; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
SIRT1 is required for long-term growth of human mesenchymal stem cells.
Topics: Adipose Tissue; Adult; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Female; Gene Knockdown Techniques; Humans; Male; Mesenchymal Stem Cells; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation; Young Adult | 2012 |
Co-expression of VpROMT gene from Chinese wild Vitis pseudoreticulata with VpSTS in tobacco plants and its effects on the accumulation of pterostilbene.
Topics: Acetates; Acyltransferases; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Conserved Sequence; Cyclopentanes; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Genetic Enhancement; Methyltransferases; Molecular Sequence Annotation; Nicotiana; Oxylipins; Phylogeny; Plant Diseases; Plant Growth Regulators; Plant Leaves; Plant Proteins; Plant Roots; Plants, Genetically Modified; Resveratrol; Saccharomycetales; Sequence Analysis, DNA; Stilbenes; Ultraviolet Rays; Vitis | 2012 |
Methoxy stilbenes as potent, specific, untransported, and noncytotoxic inhibitors of breast cancer resistance protein.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Female; HEK293 Cells; Humans; Mitoxantrone; Neoplasm Proteins; Resveratrol; Stilbenes | 2012 |
Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice.
Topics: Animals; Cell Line; Cells, Cultured; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Male; Mice; Receptors, Estrogen; Resveratrol; Sex Factors; Stilbenes | 2012 |
Resveratrol ameliorates the deleterious effect of severe acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Pancreatitis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Taurocholic Acid; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2012 |
[Differential analysis of two-dimensional gel electrophoresis profiles in the protective effects of resveratrol on HaCaT cells induced by UVB irradiation].
Topics: Cell Line; Electrophoresis, Gel, Two-Dimensional; Histones; Humans; Keratinocytes; Proteins; Radiation Injuries; Radiation-Protective Agents; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Transcription Factors, TFII; Ultraviolet Rays | 2011 |
A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis.
Topics: Algorithms; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Carcinoma; Chemoprevention; Drug Evaluation, Preclinical; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2012 |
Resveratrol inhibits interleukin 1β-mediated inducible nitric oxide synthase expression in articular chondrocytes by activating SIRT1 and thereby suppressing nuclear factor-κB activity.
Topics: Active Transport, Cell Nucleus; Animals; Cell Nucleus; Chondrocytes; DNA; Gene Expression Regulation, Enzymologic; Interleukin-1beta; Joints; Nitric Oxide; Nitric Oxide Synthase Type II; Osteoarthritis; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factor RelA; Transcriptional Activation | 2012 |
Formation of dopamine quinone-DNA adducts and their potential role in the etiology of Parkinson's disease.
Topics: Acetylcysteine; Antioxidants; Benzoquinones; DNA Adducts; Dopamine; Humans; Hydrogen-Ion Concentration; Kinetics; Melatonin; Monophenol Monooxygenase; Parkinson Disease; Resveratrol; Stilbenes; Thioctic Acid | 2011 |
Regioselective glucosidation of trans-resveratrol in Escherichia coli expressing glucosyltransferase from Phytolacca americana.
Topics: Escherichia coli; Gene Expression; Glucosyltransferases; Phytolacca americana; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes; Substrate Specificity; Time Factors | 2012 |
Resveratrol protects mouse embryonic stem cells from ionizing radiation by accelerating recovery from DNA strand breakage.
Topics: Animals; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; DNA Breaks; DNA Repair; Embryonic Stem Cells; Genomic Instability; Mice; Radiation-Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Modulation of microRNA 20b with resveratrol and longevinex is linked with their potent anti-angiogenic action in the ischaemic myocardium and synergestic effects of resveratrol and γ-tocotrienol.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Chromans; Down-Regulation; Drug Synergism; Gene Expression Profiling; Heart; Hypoxia-Inducible Factor 1, alpha Subunit; Male; MicroRNAs; Microscopy, Confocal; Multivariate Analysis; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A; Vitamin E | 2012 |
Resveratrol causes cell cycle arrest, decreased collagen synthesis, and apoptosis in rat intestinal smooth muscle cells.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Cell Cycle; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Cells, Cultured; Collagen; Collagen Type I; Collagen Type III; Colon; DNA Fragmentation; Female; G1 Phase; Gene Expression; Insulin-Like Growth Factor I; Intestinal Mucosa; Myocytes, Smooth Muscle; Phosphatidylserines; Rats; Rats, Inbred Lew; Resveratrol; S Phase; Stilbenes; Transforming Growth Factor beta1 | 2012 |
The phytoalexin resveratrol regulates the initiation of hypersensitive cell death in Vitis cell.
Topics: Actin Cytoskeleton; Acyltransferases; Alkalies; Bacterial Outer Membrane Proteins; Cell Death; Cell Proliferation; Cytoskeleton; Enzyme Induction; Gene Expression Regulation, Plant; Microtubules; Models, Biological; Phytoalexins; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Sesquiterpenes; Stilbenes; Vitis | 2011 |
Differences in the activities of resveratrol and ascorbic acid in protection of ethanol-induced oxidative DNA damage in human peripheral lymphocytes.
Topics: Adult; Ascorbic Acid; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Ethanol; Female; Humans; Lymphocytes; Male; Oxidative Stress; Resveratrol; Stilbenes; Young Adult | 2012 |
Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation.
Topics: Administration, Oral; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Inflammation; Injections, Intraperitoneal; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Phosphorylation; Resveratrol; Retinitis; Ribonucleotides; Sirtuin 1; Stilbenes; Transcription Factor RelA; Vascular Endothelial Growth Factor A | 2011 |
In vitro absorption of dietary trans-resveratrol from boiled and roasted peanuts in Caco-2 cells.
Topics: Arachis; Caco-2 Cells; Digestion; Hot Temperature; Humans; In Vitro Techniques; Intestinal Absorption; Resveratrol; Seeds; Stilbenes | 2011 |
Influence of resveratrol on oxidative damage in genomic DNA and apoptosis induced by cisplatin.
Topics: Animals; Antimutagenic Agents; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Cisplatin; DNA Damage; Dose-Response Relationship, Drug; Male; Mice; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents streptozotocin-induced diabetes by inhibiting the apoptosis of pancreatic β-cell and the cleavage of poly (ADP-ribose) polymerase.
Topics: Animals; Antioxidants; Apoptosis; Blood Glucose; Caspase 3; Diabetes Mellitus, Type 1; Enzyme Activation; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; In Situ Nick-End Labeling; Insulin-Secreting Cells; Male; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteolysis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin; Time Factors | 2012 |
Activation of Sirt1 by resveratrol inhibits TNF-α induced inflammation in fibroblasts.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line; Cell Proliferation; Fibroblasts; Inflammation; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 9; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2011 |
Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
Topics: Anthracenes; Butadienes; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavanones; Glucose; Hesperidin; Humans; Hyperglycemia; Imidazoles; Intercellular Adhesion Molecule-1; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes; Up-Regulation; Veins | 2011 |
Resveratrol: is selectivity opening the key to therapeutic effects?
Topics: Animals; Anti-Inflammatory Agents; Insulin; Insulin Resistance; Male; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Orthogonal test design for optimisation of extraction of trans-resveratrol from Pinot Noir-grape pomace.
Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Crystallization; Microwaves; Resveratrol; Stilbenes; Temperature; Vitis | 2012 |
Determination of resveratrol and its sulfate and glucuronide metabolites in plasma by LC-MS/MS and their pharmacokinetics in dogs.
Topics: Animals; Body Weight; Calibration; Chromatography, Liquid; Dogs; Dose-Response Relationship, Drug; Drug Stability; Female; Glucuronides; Humans; Limit of Detection; Male; Molecular Structure; Rats; Reference Standards; Reproducibility of Results; Resveratrol; Species Specificity; Stilbenes; Sulfuric Acid Esters; Tandem Mass Spectrometry; Time Factors | 2012 |
An optimum fermentation model established by genetic algorithm for biotransformation from crude polydatin to resveratrol.
Topics: Algorithms; Aspergillus niger; Biotransformation; Fermentation; Glucosides; Models, Biological; Nonlinear Dynamics; Resveratrol; Stilbenes | 2012 |
Resveratrol-mediated autophagy requires WIPI-1-regulated LC3 lipidation in the absence of induced phagophore formation.
Topics: Androstadienes; Animals; Autophagy; Autophagy-Related Protein 12; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Autophagy-Related Proteins; Carrier Proteins; Cell Line; Green Fluorescent Proteins; Humans; Lipids; Membrane Proteins; Mice; Microtubule-Associated Proteins; Phagosomes; Phosphatidylinositol Phosphates; Protein Transport; Recombinant Fusion Proteins; Resveratrol; Small Ubiquitin-Related Modifier Proteins; Stilbenes; Ubiquitin-Activating Enzymes; Wortmannin | 2011 |
The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Diet, High-Fat; Drosophila melanogaster; Female; Longevity; Male; Oxidative Stress; Resveratrol; Ribonucleotide Reductases; Signal Transduction; Stilbenes | 2013 |
Novel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents.
Topics: Animals; Carboxylic Acids; Cholesterol; Diabetes Mellitus, Experimental; Fenofibrate; Flavonoids; Hyperlipidemias; Hypolipidemic Agents; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Molecular Structure; Polyethylene Glycols; Resveratrol; Stilbenes; Surface-Active Agents; Triglycerides | 2012 |
Neurons from senescence-accelerated SAMP8 mice are protected against frailty by the sirtuin 1 promoting agents melatonin and resveratrol.
Topics: Animals; Cells, Cultured; Melatonin; Membrane Potentials; Mice; Neurons; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury.
Topics: Aldehydes; Animals; Bile Ducts; Cell Proliferation; Cholestasis; Collagen Type I; Hepatocytes; Inflammation; Interleukin-6; Kupffer Cells; Ligation; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Resveratrol; RNA, Messenger; Stilbenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha | 2011 |
Synthesis and study of new paramagnetic resveratrol analogues.
Topics: Animals; Anti-Inflammatory Agents; Benzothiazoles; Cell Line; Free Radical Scavengers; Lipopolysaccharides; Macrophages; Mice; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfonic Acids; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol enhances the therapeutic effect of temozolomide against malignant glioma in vitro and in vivo by inhibiting autophagy.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Dacarbazine; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Glioma; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes; Temozolomide; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Resveratrol acts as a topoisomerase II poison in human glioma cells.
Topics: Antigens, Neoplasm; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Glioma; Histones; Humans; Models, Molecular; Protein Kinases; Protein Serine-Threonine Kinases; Resveratrol; Stilbenes; Topoisomerase II Inhibitors; Tumor Suppressor Proteins | 2012 |
Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies.
Topics: Animals; Apoptosis; Arylsulfotransferase; Cell Line, Tumor; Cells, Cultured; Glioblastoma; Humans; Immunohistochemistry; Molecular Chaperones; Protein Inhibitors of Activated STAT; Rats; Resveratrol; STAT3 Transcription Factor; Stilbenes; Sulfotransferases; Tyrphostins | 2011 |
Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells.
Topics: Acyltransferases; Coenzyme A Ligases; Genetic Vectors; PDZ Domains; Protein Engineering; Recombinant Fusion Proteins; Resveratrol; Saccharomyces cerevisiae; src Homology Domains; Stilbenes | 2012 |
Resveratrol inhibited GH3 cell growth and decreased prolactin level via estrogen receptors.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Culture Media, Conditioned; Cyclin D3; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; G1 Phase; Humans; Indicators and Reagents; Microscopy, Electron, Transmission; Phosphorylation; Pituitary Neoplasms; Prolactin; Prolactinoma; Receptors, Estrogen; Resting Phase, Cell Cycle; Resveratrol; Stilbenes | 2012 |
Diesel exhaust particulate extracts inhibit transcription of nuclear respiratory factor-1 and cell viability in human umbilical vein endothelial cells.
Topics: Cell Proliferation; Cell Survival; Cells, Cultured; Drug Antagonism; Electron Transport Complex IV; Estradiol; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Nuclear Respiratory Factor 1; Particulate Matter; Raloxifene Hydrochloride; Resveratrol; Stilbenes; Tamoxifen; Transcription, Genetic; Vehicle Emissions | 2012 |
A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Butadienes; Cell Death; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Glutamine; Humans; Male; Mitochondria; Nitriles; Prostatic Neoplasms; Resveratrol; Stilbenes | 2011 |
Phenolic composition of the edible parts (flesh and skin) of Bordô grape (Vitis labrusca) using HPLC-DAD-ESI-MS/MS.
Topics: Anthocyanins; Brazil; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonols; Fruit; Gallic Acid; Phenols; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry; Vitis | 2011 |
Production of resveratrol from p-coumaric acid in recombinant Saccharomyces cerevisiae expressing 4-coumarate:coenzyme A ligase and stilbene synthase genes.
Topics: Acyltransferases; Arabidopsis Proteins; Arachis; Batch Cell Culture Techniques; Biotechnology; Cloning, Molecular; Coenzyme A Ligases; Coumaric Acids; Culture Media; Humans; Propionates; Recombination, Genetic; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2011 |
Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1.
Topics: Animals; Benzamides; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Male; Myocardial Contraction; Naphthols; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Wounds and Injuries | 2012 |
Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets.
Topics: Antineoplastic Agents; Aromatase; Binding Sites; Catalytic Domain; Chemoprevention; Computer Simulation; Enzyme Activation; Humans; NAD(P)H Dehydrogenase (Quinone); Neoplasms; NF-kappa B; Resveratrol; Stilbenes; Structure-Activity Relationship; Thiadiazoles | 2012 |
Resveratrol mitigates lipopolysaccharide- and Aβ-mediated microglial inflammation by inhibiting the TLR4/NF-κB/STAT signaling cascade.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Cytokines; Disease Models, Animal; Drug Interactions; Humans; I-kappa B Proteins; Inflammation Mediators; Lipopolysaccharides; Male; Mice; Mice, Transgenic; Microglia; NF-KappaB Inhibitor alpha; Presenilin-1; Resveratrol; Signal Transduction; Statistics, Nonparametric; Stilbenes; Time Factors; Toll-Like Receptors; Tumor Necrosis Factor-alpha | 2012 |
Radical-induced oxidation of trans-resveratrol.
Topics: Gamma Rays; Hydroxyl Radical; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Sirtuin 1 regulates skeletal myoblast survival and enhances differentiation in the presence of resveratrol.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Silencing; Insulin-Like Growth Factor I; Mice; Models, Animal; Myoblasts, Skeletal; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
Antinociceptive interaction between benfotiamine and resveratrol in capsaicin-induced licking.
Topics: Analgesics; Animals; Capsaicin; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Mice, Inbred ICR; Resveratrol; Stilbenes; Thiamine | 2009 |
Enhanced anthocyanins and resveratrol production in Vitis vinifera cell suspension culture by indanoyl-isoleucine, N-linolenoyl-L-glutamine and insect saliva.
Topics: Animals; Anthocyanins; Cell Culture Techniques; Culture Media; Food Technology; Glutamine; Hydrogen-Ion Concentration; Indans; Isoleucine; Linolenic Acids; Manduca; Resveratrol; Saliva; Stilbenes; Vitis | 2012 |
Resveratrol induces Sirt1-dependent apoptosis in 3T3-L1 preadipocytes by activating AMPK and suppressing AKT activity and survivin expression.
Topics: 3T3-L1 Cells; Adipocytes, White; AMP-Activated Protein Kinases; Animals; Antioxidants; Apoptosis; Caspase Inhibitors; Caspases; Chromatin Assembly and Disassembly; Down-Regulation; Gene Silencing; Inhibitor of Apoptosis Proteins; Membrane Potential, Mitochondrial; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Repressor Proteins; Resveratrol; RNA, Small Interfering; S Phase; Second Messenger Systems; Sirtuin 1; Stilbenes; Survivin; Up-Regulation | 2012 |
Treatment with low-dose resveratrol reverses cardiac impairment in obese prone but not in obese resistant rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Blood Glucose; Diet, High-Fat; Disease Resistance; Disease Susceptibility; Echocardiography; Heart; Heart Diseases; Hyperglycemia; Hyperinsulinism; Male; Obesity; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Nitric oxide triggers apoptosis in A375 human melanoma cells treated with capsaicin and resveratrol.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Capsaicin; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cytochromes c; Humans; Melanoma; Mitochondria; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
Genetics. Aging genes: the sirtuin story unravels.
Topics: Aging; Animals; Caloric Restriction; Humans; Longevity; Publishing; Reproducibility of Results; Resveratrol; Sirtuins; Stilbenes; Yeasts | 2011 |
Resveratrol modifies tephritid fruit fly response to radiation but not nutritional stress.
Topics: Animals; Diet; Dietary Supplements; Female; Plant Oils; Resveratrol; Stilbenes; Stress, Physiological; Tephritidae | 2012 |
Repeated resveratrol administration confers lasting protection against neuronal damage but induces dose-related alterations of behavioral impairments after global ischemia.
Topics: Animals; Behavior, Animal; Blood Glucose; Body Weight; Brain Ischemia; Dose-Response Relationship, Drug; Exploratory Behavior; Hippocampus; Male; Maze Learning; Motor Activity; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins.
Topics: AMP-Activated Protein Kinases; Biological Transport; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Lipoproteins, LDL; Peptide Hydrolases; Promoter Regions, Genetic; Receptors, LDL; Resveratrol; RNA Interference; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Stilbenes; Time Factors; Transcriptional Activation; Transfection; Up-Regulation | 2012 |
Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism.
Topics: Acetylation; Animals; Cell Line; Dexamethasone; Forkhead Transcription Factors; Muscle Fibers, Skeletal; Muscle Proteins; Nerve Tissue Proteins; Rats; Resveratrol; Sirtuin 1; SKP Cullin F-Box Protein Ligases; Stilbenes; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2012 |
Resveratrol, by modulating RNA processing factor levels, can influence the alternative splicing of pre-mRNAs.
Topics: Alternative Splicing; Exons; HEK293 Cells; HeLa Cells; Humans; Intracellular Space; Nuclear Proteins; Protein Transport; Resveratrol; RNA Precursors; RNA Processing, Post-Transcriptional; RNA-Binding Proteins; RNA, Messenger; Serine-Arginine Splicing Factors; Sirtuin 1; Stilbenes | 2011 |
Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades.
Topics: Adenocarcinoma; Adrenomedullin; Biomarkers, Tumor; Case-Control Studies; Catechin; Cell Line, Tumor; Cobalt; Endometrial Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Grading; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation; Vascular Endothelial Growth Factor A | 2012 |
The effects of resveratrol on cyclooxygenase-1 and -2, nuclear factor kappa beta, matrix metalloproteinase-9, and sirtuin 1 mRNA expression in hearts of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Cardiomyopathies; Cyclooxygenase 1; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Disease Models, Animal; Gene Expression Regulation; Heart; Male; Matrix Metalloproteinase 9; NF-kappa B; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes | 2011 |
Potentiation of neuronal insulin signaling and glucose uptake by resveratrol: the involvement of AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Line, Tumor; Glucose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Mice; Neuroblastoma; Neurons; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Resveratrol; Signal Transduction; Stilbenes | 2011 |
The effect of resveratrol on the prevention of cisplatin ototoxicity.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Loss, Sensorineural; Otoacoustic Emissions, Spontaneous; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Curcumin; Drug Screening Assays, Antitumor; Humans; Mice; Protein Structure, Tertiary; Resveratrol; Stilbenes; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2012 |
Resveratrol as a kcat type inhibitor for tyrosinase: potentiated melanogenesis inhibitor.
Topics: Agaricales; Animals; Cell Differentiation; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Kinetics; Levodopa; Melanins; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Resveratrol; Stilbenes; Tyrosine | 2012 |
Investigation of ocular neovascularization-related genes and oxidative stress in diabetic rat eye tissues after resveratrol treatment.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Eye; Male; Matrix Metalloproteinase 9; Neovascularization, Pathologic; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Streptozocin; Vascular Endothelial Growth Factor A | 2012 |
Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Transformation, Neoplastic; Copper; Dietary Supplements; Female; Genomic Instability; Mammary Neoplasms, Experimental; Microsatellite Repeats; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2011 |
Resveratrol inhibits the release of soluble fms-like tyrosine kinase (sFlt-1) from human placenta.
Topics: Cells, Cultured; Cytokines; Early Growth Response Protein 1; Enzyme Inhibitors; Female; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Placenta; Pre-Eclampsia; Pregnancy; Resveratrol; Stilbenes; Up-Regulation; Vascular Endothelial Growth Factor Receptor-1 | 2012 |
BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells.
Topics: BRCA1 Protein; Breast Neoplasms; Carcinogens; DNA Methylation; Estradiol; Estrogen Receptor alpha; Exons; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Ligands; MCF-7 Cells; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Response Elements; Resveratrol; Sequence Analysis, DNA; Stilbenes | 2012 |
Identification of a new stilbene-derived inducer of paraoxonase 1 and ligand of the Aryl hydrocarbon Receptor.
Topics: Acrylonitrile; Aryldialkylphosphatase; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; Humans; Ligands; Molecular Structure; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2012 |
Resveratrol reduces TNF-α-induced U373MG human glioma cell invasion through regulating NF-κB activation and uPA/uPAR expression.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Collagen; Drug Combinations; Gene Expression Regulation, Neoplastic; Glioma; Humans; Laminin; Neoplasm Invasiveness; NF-kappa B; Proteoglycans; Receptors, Urokinase Plasminogen Activator; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator | 2011 |
[Protective effects of resveratrol on lipopolysaccharide-induced inflammatory toxicity in primary cortical astrocyte cultures].
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cerebral Cortex; Inflammation; Lipopolysaccharides; Nitric Oxide; Nitric Oxide Synthase Type II; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2011 |
Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Female; Humans; Infusions, Parenteral; Mice; Mice, Inbred NOD; Mice, SCID; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes | 2012 |
Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis.
Topics: Allyl Compounds; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Curcumin; Disulfides; Drug Synergism; Humans; Resveratrol; Sarcoma; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Topics: Animals; Cell Count; Gene Expression Regulation; Gene Knockout Techniques; High-Temperature Requirement A Serine Peptidase 2; Longevity; Mice; Mitochondrial Proteins; Motor Activity; Neostriatum; Oxidative Stress; Resveratrol; Serine Endopeptidases; Signal Transduction; Stilbenes; Transcription Factor CHOP; Ubiquinone | 2011 |
Resveratrol improves insulin resistance of catch-up growth by increasing mitochondrial complexes and antioxidant function in skeletal muscle.
Topics: Animals; Antioxidants; Caloric Restriction; Citrate (si)-Synthase; Glucose; Insulin Resistance; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Refeeding Syndrome; Resveratrol; Stilbenes | 2012 |
Resveratrol attenuates doxorubicin-induced cardiomyocyte death via inhibition of p70 S6 kinase 1-mediated autophagy.
Topics: Animals; Animals, Newborn; Autophagy; Cell Death; Cells, Cultured; Doxorubicin; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Stilbenes | 2012 |
Resveratrol induces gastric cancer cell apoptosis via reactive oxygen species, but independent of sirtuin1.
Topics: Apoptosis; Cell Proliferation; Humans; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Stomach Neoplasms; Tumor Cells, Cultured | 2012 |
PDCD4 expression inversely correlated with miR-21 levels in gastric cancers.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line, Tumor; Cell Survival; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Male; MicroRNAs; Middle Aged; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; Stilbenes; Stomach Neoplasms; Tissue Array Analysis | 2012 |
Combinations of resveratrol, cisplatin and oxaliplatin applied to human ovarian cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cisplatin; DNA Adducts; Drug Synergism; Female; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Oxaliplatin; Resveratrol; Stilbenes | 2012 |
Combination of glucan, resveratrol and vitamin C demonstrates strong anti-tumor potential.
Topics: Animals; Antibody Formation; Antioxidants; Ascorbic Acid; beta-Glucans; Carcinoma, Lewis Lung; Drug Therapy, Combination; Female; Granulocytes; Immunologic Factors; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Ovalbumin; Phagocytosis; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits mucin gene expression, production and secretion from airway epithelial cells.
Topics: Animals; Cell Line; Epidermal Growth Factor; Epithelial Cells; Gene Expression; Humans; Male; Mucin 5AC; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Trachea; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2012 |
Differential protective effects of quercetin, resveratrol, rutin and epigallocatechin gallate against mitochondrial dysfunction induced by indomethacin in Caco-2 cells.
Topics: Adenosine Triphosphate; Caco-2 Cells; Catechin; Drug Interactions; Electron Transport Complex I; Gastrointestinal Diseases; Humans; Indomethacin; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Diseases; Quercetin; Resveratrol; Rutin; Stilbenes; Superoxides | 2012 |
Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Caspase 3; Caspase 8; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; HT29 Cells; Humans; Oligopeptides; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cellular Senescence; Culture Media, Conditioned; Cytokines; Interleukins; Macaca mulatta; Models, Animal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Oxidative Stress; Oxygen; Phenanthridines; Resveratrol; Stilbenes; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2012 |
SirT1--a sensor for monitoring self-renewal and aging process in retinal stem cells.
Topics: Adult; Aged; Animals; Antioxidants; Biosensing Techniques; Cell Proliferation; Cells, Cultured; Cellular Senescence; Child; Female; Humans; Male; Middle Aged; Monitoring, Physiologic; Rats; Rats, Sprague-Dawley; Resveratrol; Retina; Sirtuin 1; Stem Cells; Stilbenes; Young Adult | 2010 |
Resveratrol protects rats from Aβ-induced neurotoxicity by the reduction of iNOS expression and lipid peroxidation.
Topics: Amyloid beta-Peptides; Animals; Heme Oxygenase-1; Hippocampus; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Protective Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Resveratrol; Rotarod Performance Test; Stilbenes | 2011 |
Resveratrate protects human skin from damage due to repetitive ultraviolet irradiation.
Topics: Humans; Resveratrol; Skin; Stilbenes; Sunburn; Ultraviolet Rays | 2013 |
Enhanced anti-inflammatory effect of resveratrol and EPA in treated endotoxin-activated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line, Transformed; Dietary Supplements; Eicosapentaenoic Acid; Gene Expression Profiling; Gene Expression Regulation; Inflammation Mediators; Lipopolysaccharides; Macrophage Activation; Macrophages; MAP Kinase Signaling System; Mice; Nitric Oxide; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Oxidoreductases; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
Does the combination of resveratrol with Al (III) and Zn (II) improve its antioxidant activity?
Topics: Aluminum; Antioxidants; Biphenyl Compounds; Picrates; Resveratrol; Stilbenes; Zinc | 2011 |
Resveratrol plus ethanol counteract the ethanol-induced impairment of energy metabolism: ³¹P NMR study of ATP and sn-glycerol-3-phosphate on isolated and perfused rat liver.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Ethanol; Glycerophosphates; Liver; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Resveratrol protects left ventricle by increasing adenylate kinase and isocitrate dehydrogenase activities in rats with myocardial infarction.
Topics: Adenylate Kinase; Animals; Antioxidants; Blotting, Western; Cardiotonic Agents; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Energy Metabolism; Enzyme Activation; Immunohistochemistry; Isocitrate Dehydrogenase; Male; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Ventricular Remodeling | 2011 |
Resveratrol causes antiatherogenic effects in an animal model of atherosclerosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cholesterol, Dietary; Disease Models, Animal; Drug Evaluation, Preclinical; Hypercholesterolemia; Male; Platelet Aggregation Inhibitors; Rabbits; Random Allocation; Resveratrol; Statistics, Nonparametric; Stilbenes | 2012 |
Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Microscopy, Confocal; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteomics; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Synthesis and evaluation of ¹⁸F-labeled styryltriazole and resveratrol derivatives for β-amyloid plaque imaging.
Topics: Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Fluorine Radioisotopes; Male; Mice; Mice, Inbred ICR; Peptide Fragments; Plaque, Amyloid; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Resveratrol; Stereoisomerism; Stilbenes; Structure-Activity Relationship; Styrenes; Tissue Distribution; Triazoles | 2012 |
Resveratrol inhibits protein translation in hepatic cells.
Topics: AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Enzyme Activation; Eukaryotic Initiation Factor-2; Eukaryotic Initiation Factor-4F; Liver; Liver Neoplasms; Phosphorylation; Protein Biosynthesis; Protein Kinase Inhibitors; Protein Stability; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Transcription Factors | 2011 |
Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Inducing Factor; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Caspase 9; Cell Line, Tumor; Cell Survival; Enzyme Activation; Humans; Lung Neoplasms; Membrane Proteins; Mitochondria; Proto-Oncogene Proteins; Resveratrol; Signal Transduction; Stilbenes | 2012 |
High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol.
Topics: Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Fibronectins; Gene Expression Regulation; Glucose; JNK Mitogen-Activated Protein Kinases; Mesangial Cells; NADPH Oxidases; NF-kappa B; Oxidative Stress; Phosphorylation; Protein Subunits; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Resveratrol, a polyphenol phytoalexin, protects cardiomyocytes against anoxia/reoxygenation injury via the TLR4/NF-κB signaling pathway.
Topics: Animals; Apoptosis; Caspase 3; Cell Hypoxia; Cell Survival; Cells, Cultured; Interleukin-1beta; L-Lactate Dehydrogenase; Myocytes, Cardiac; NF-kappa B; Phytoalexins; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Sesquiterpenes; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2012 |
Quantum-mechanical computations on the electronic structure of trans-resveratrol and trans-piceatannol: a theoretical study of the stacking interactions in trans-resveratrol dimers.
Topics: Dimerization; Hydrogen Bonding; Models, Chemical; Models, Molecular; Quantum Theory; Resveratrol; Stilbenes | 2012 |
Cardiovascular researcher fabricated data in studies of red wine.
Topics: Cardiology; Connecticut; History, 21st Century; Humans; Resveratrol; Scientific Misconduct; Stilbenes; United States; Vitis; Wine | 2012 |
Resveratrol dimers are novel sphingosine kinase 1 inhibitors and affect sphingosine kinase 1 expression and cancer cell growth and survival.
Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Humans; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Stilbenes | 2012 |
Anti-inflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-κB activation in Caco-2 and SW480 human colon cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dietary Supplements; Down-Regulation; Enterocytes; Humans; I-kappa B Proteins; Inflammatory Bowel Diseases; Lipopolysaccharides; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Protein Processing, Post-Translational; Proteolysis; Resveratrol; RNA, Messenger; Stilbenes; Toll-Like Receptor 4 | 2012 |
Biological effects of the plant-derived polyphenol resveratrol in human articular cartilage and chondrosarcoma cells.
Topics: Apoptosis; Bone Morphogenetic Protein 7; Bone Neoplasms; Cartilage, Articular; Cell Line, Tumor; Chondrocytes; Chondrosarcoma; Cytokines; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; Interleukin-1beta; Metabolism; Oncogene Protein v-akt; Peptide Hydrolases; Plants; Polyphenols; Proteasome Endopeptidase Complex; Proteins; Resveratrol; Signal Transduction; Stilbenes; Transcription Factors | 2012 |
Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse.
Topics: Animals; Biomechanical Phenomena; Body Weight; Dependovirus; Dietary Supplements; Gene Transfer Techniques; Mice; Mice, Inbred mdx; Muscle Contraction; Muscle Fatigue; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscular Dystrophy, Animal; Myosins; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Recovery of Function; Resveratrol; Stilbenes; Trans-Activators; Transcription Factors | 2012 |
[Involvement of p38-p53 signal pathway in resveratrol-induced apoptosis in MCF-7 cells].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzothiazoles; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; MCF-7 Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Signal Transduction; Stilbenes; Toluene; Tumor Suppressor Protein p53 | 2011 |
Aronia melanocarpa extract suppresses the biotoxicity of homocysteine and its metabolite on the hemostatic activity of fibrinogen and plasma.
Topics: Adult; Anticoagulants; Antioxidants; Blood Coagulation; Cardiovascular Diseases; Coagulants; Dietary Supplements; Fibrinogen; Fruit; Homocysteine; Humans; Hyperhomocysteinemia; Models, Biological; Oxidative Stress; Photinia; Plant Extracts; Poland; Polymerization; Resveratrol; Stilbenes | 2012 |
Protective role of resveratrol against cisplatin induced ototoxicity in guinea pigs.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cisplatin; Cochlea; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hearing Loss, Sensorineural; Male; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Control of stability of cyclin D1 by quinone reductase 2 in CWR22Rv1 prostate cancer cells.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Humans; Male; Phosphorylation; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; Quinone Reductases; Resveratrol; Retinoblastoma Protein; RNA Interference; RNA, Small Interfering; Stilbenes | 2012 |
Resveratrol reduces vacuous chewing movements induced by acute treatment with fluphenazine.
Topics: Animals; Fluphenazine; Male; Mastication; Movement Disorders; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Hypoxanthine-xanthine oxidase down-regulates GLUT1 transcription via SIRT1 resulting in decreased glucose uptake in human placenta.
Topics: Antioxidants; Biological Transport; Down-Regulation; Female; Glucose; Glucose Transporter Type 1; Humans; Oxidative Stress; Placenta; Pregnancy; Pregnancy Proteins; Resveratrol; Sirtuin 1; Stilbenes; Xanthine Oxidase | 2012 |
Novel nanocomposite stent coating releasing resveratrol and quercetin reduces neointimal hyperplasia and promotes re-endothelialization.
Topics: Angioplasty; Animals; Antimitotic Agents; Cell Proliferation; Constriction, Pathologic; Drug-Eluting Stents; Endothelium, Vascular; Female; Hyperplasia; Male; Nanocomposites; Neointima; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.
Topics: Acute Pain; AMP-Activated Protein Kinases; Animals; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4F; Extracellular Signal-Regulated MAP Kinases; Hyperalgesia; Interleukin-6; Male; Mice; Mice, Inbred ICR; Pain, Postoperative; Protein Biosynthesis; Resveratrol; Sensory Receptor Cells; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; TOR Serine-Threonine Kinases; Trigeminal Ganglion | 2012 |
Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol.
Topics: 3-Hydroxybutyric Acid; Acyl Coenzyme A; Animals; Calcium; Cell Line, Tumor; Diacylglycerol Kinase; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Glycerides; Glycerol; Insulin; Insulin Secretion; Islets of Langerhans; Oxidation-Reduction; Oxygen Consumption; Piperidines; Quinazolinones; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
The role of nutraceutical supplements in the treatment of dyslipidemia.
Topics: Atherosclerosis; Dietary Fats; Dietary Supplements; Dyslipidemias; Humans; Lipoproteins; Lipoproteins, VLDL; Oxidative Stress; Pantetheine; Resveratrol; Stilbenes; Tocotrienols; Triglycerides; Vascular Diseases; Vasodilator Agents | 2012 |
Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclosporine; Cytoprotection; Glucosides; KATP Channels; Lysosomes; Membrane Potential, Mitochondrial; Mitochondria, Muscle; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Norepinephrine; Rats; Resveratrol; Shock, Hemorrhagic; Stilbenes | 2012 |
Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms.
Topics: Animals; Aorta; Body Weight; Cattle; Cells, Cultured; Cellular Senescence; Diet, High-Fat; Endothelium, Vascular; Glucose; Lipids; Male; NADPH Oxidases; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Inhibition of Na⁺-H⁺ exchange as a mechanism of rapid cardioprotection by resveratrol.
Topics: Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Heart Ventricles; Hydrogen Peroxide; In Vitro Techniques; Membrane Potential, Mitochondrial; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Sodium; Sodium-Hydrogen Exchangers; Stilbenes; Ventricular Function | 2012 |
Effect of antioxidants resveratrol and quercetin on in vitro evaluation of frozen ram sperm.
Topics: Animals; Antioxidants; Cryopreservation; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Protective Agents; Quercetin; Resveratrol; Semen Analysis; Sheep; Spermatozoa; Stilbenes | 2012 |
Skin toxicity from external beam radiation therapy in breast cancer patients: protective effects of Resveratrol, Lycopene, Vitamin C and anthocianin (Ixor®).
Topics: Adult; Aged; Aged, 80 and over; Anthocyanins; Antioxidants; Ascorbic Acid; Breast Neoplasms; Carotenoids; Female; Humans; Lycopene; Middle Aged; Prognosis; Radiation-Protective Agents; Radiodermatitis; Radiotherapy, Conformal; Resveratrol; Stilbenes; Vitamins | 2012 |
The tubule pathology of septic acute kidney injury: a neglected area of research comes of age.
Topics: Acute Kidney Injury; Animals; Antioxidants; Kidney; Male; Microcirculation; Resveratrol; Sepsis; Stilbenes | 2012 |
Resveratrol-derived stilbenoids and biological activity evaluation of seed extracts of Cenchrus echinatus L.
Topics: Caco-2 Cells; Cenchrus; Humans; Magnetic Resonance Spectroscopy; Plant Extracts; Resveratrol; Seeds; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2012 |
Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line.
Topics: Azacitidine; Base Sequence; Cell Line, Tumor; Cell Survival; Curcumin; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; DNA, Complementary; Epigenesis, Genetic; Fanconi Anemia Complementation Group F Protein; Humans; Inhibitory Concentration 50; Promoter Regions, Genetic; Resveratrol; Sequence Analysis, DNA; Stilbenes; Transcription, Genetic | 2012 |
Spectroscopy and kinetics of tyrosinase catalyzed trans-resveratrol oxidation.
Topics: Biocatalysis; Kinetics; Monophenol Monooxygenase; Oxidation-Reduction; Resveratrol; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Stereoisomerism; Stilbenes | 2012 |
HIV-1 Tat protein impairs adipogenesis and induces the expression and secretion of proinflammatory cytokines in human SGBS adipocytes.
Topics: Adipocytes; Adipogenesis; Cytokines; Gene Expression Regulation; HIV Infections; HIV-1; HIV-Associated Lipodystrophy Syndrome; Humans; Inflammation; Resveratrol; Rosiglitazone; Sesquiterpenes; Stilbenes; tat Gene Products, Human Immunodeficiency Virus; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2012 |
Resveratrol inhibits proliferation and induces apoptosis through the hedgehog signaling pathway in pancreatic cancer cell.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Hedgehog Proteins; Humans; Pancreatic Neoplasms; Resveratrol; Stilbenes | 2011 |
SirT1 confers hypoxia-induced radioresistance via the modulation of c-Myc stabilization on hepatoma cells.
Topics: Acetylation; Cell Hypoxia; Gamma Rays; Hep G2 Cells; Histone Deacetylase Inhibitors; Humans; Micronucleus Tests; Neoplasm Proteins; Niacinamide; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Stability; Proto-Oncogene Proteins c-myc; Radiation Tolerance; Resveratrol; Sirtuin 1; Stilbenes; Ubiquitin | 2012 |
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue, White; Aging; AMP-Activated Protein Kinase Kinases; Animals; Caloric Restriction; Cyclic Nucleotide Phosphodiesterases, Type 4; Diet; Glucose Intolerance; Guanine Nucleotide Exchange Factors; Mice; Models, Molecular; Muscle, Skeletal; NAD; Obesity; Protein Kinases; Resveratrol; Rolipram; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
Eradication of Propionibacterium acnes biofilms by plant extracts and putative identification of icariin, resveratrol and salidroside as active compounds.
Topics: Acne Vulgaris; Biofilms; Dolichos; Drug Resistance, Bacterial; Epimedium; Flavonoids; Fruit; Glucosides; Humans; Malus; Microbial Sensitivity Tests; Phenols; Plant Extracts; Plant Roots; Polygonum; Propionibacterium acnes; Resveratrol; Rhizome; Rhodiola; Sebaceous Glands; Seeds; Stilbenes | 2012 |
Effects of resveratrol on the amelioration of insulin resistance in KKAy mice.
Topics: Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Blood Glucose; Disease Models, Animal; Glucose Metabolism Disorders; Glucose Tolerance Test; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Time Factors | 2012 |
Resveratrol nanosuspensions: interaction of preservatives with nanocrystal production.
Topics: Antioxidants; Chemistry, Pharmaceutical; Drug Stability; Drug Storage; Electrochemistry; Indicators and Reagents; Nanoparticles; Particle Size; Preservatives, Pharmaceutical; Resveratrol; Rutin; Stilbenes; Suspensions; Water | 2011 |
Pro-angiogenic effects of resveratrol in brain endothelial cells: nitric oxide-mediated regulation of vascular endothelial growth factor and metalloproteinases.
Topics: Angiogenesis Inducing Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Brain; Cadherins; Endothelial Cells; Humans; MAP Kinase Signaling System; Metalloproteases; Nitric Oxide; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Stroke; Vascular Endothelial Growth Factor A | 2012 |
Maternal resveratrol treatment during pregnancy improves adverse fetal outcomes in a rat model of severe hypoxia.
Topics: Animals; Antioxidants; Drug Evaluation, Preclinical; Female; Fetal Hypoxia; Pregnancy; Pregnancy Outcome; Rats; Resveratrol; Stilbenes | 2012 |
[Resveratrol improves coronary collateral circulation in pigs with experimental acute coronary occlusion].
Topics: Animals; Antioxidants; Collateral Circulation; Coronary Circulation; Coronary Occlusion; Coronary Vessels; Disease Models, Animal; Heart; Hemodynamics; Nitroglycerin; Resveratrol; Stilbenes; Swine | 2011 |
A resveratrol analog, phoyunbene B, induces G2/M cell cycle arrest and apoptosis in HepG2 liver cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Liver Neoplasms; M Phase Cell Cycle Checkpoints; Orchidaceae; Resveratrol; Stilbenes | 2012 |
SIRT1 overexpression decreases cisplatin-induced acetylation of NF-κB p65 subunit and cytotoxicity in renal proximal tubule cells.
Topics: Acetylation; Antineoplastic Agents; Antioxidants; Carbazoles; Cell Line; Cisplatin; Drug Resistance, Neoplasm; Humans; Kidney Tubules, Proximal; Protein Biosynthesis; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factor RelA | 2012 |
The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol.
Topics: Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Enzyme Inhibitors; Mice; Mice, Knockout; Neuronal Ceroid-Lipofuscinoses; Resveratrol; Stilbenes; Thiolester Hydrolases | 2012 |
Bioactive stilbenes from a Bacillus sp. N strain associated with a novel rhabditid entomopathogenic nematode.
Topics: Animals; Anti-Infective Agents; Bacillus; Biological Products; Nematoda; Resveratrol; Stilbenes | 2012 |
Resveratrol potentiates cytochrome P450 2 d22-mediated neuroprotection in maneb- and paraquat-induced parkinsonism in the mouse.
Topics: Animals; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dopamine; Fungicides, Industrial; Herbicides; Male; Maneb; Mice; Neuroprotective Agents; Paraquat; Parkinsonian Disorders; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2012 |
Sphingosine kinase: a key to solving the 'French Paradox'?
Topics: Antineoplastic Agents; Enzyme Inhibitors; Humans; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Stilbenes | 2012 |
Characterization of critical physical and mechanical properties of freeze-dried grape powder for development of a clinical patient delivery system.
Topics: Catechin; Cellulose; Drug Compounding; Drug Delivery Systems; Drug Stability; Drug Storage; Excipients; Freeze Drying; Humidity; Lactose; Powders; Reproducibility of Results; Resveratrol; Stilbenes; Time Factors; Vitis; Waxes | 2013 |
Resveratrol-induced augmentation of telomerase activity delays senescence of endothelial progenitor cells.
Topics: Cells, Cultured; Cellular Senescence; Endothelial Cells; Humans; Resveratrol; Stem Cells; Stilbenes; Telomerase | 2011 |
Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies.
Topics: Animals; Biological Availability; Biotransformation; Chromatography, Liquid; Glucuronides; Injections, Intra-Arterial; Male; Mice; Mice, Inbred C57BL; Models, Animal; Reference Standards; Reproducibility of Results; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Sulfates; Tandem Mass Spectrometry | 2012 |
Selective (1)O(2) quenchers, oligostilbenes, from Vitis wilsonae: structural identification and biogenetic relationship.
Topics: Biphenyl Compounds; Free Radical Scavengers; Oxygen; Picrates; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2012 |
Resveratrol inhibits LPS-induced epithelial-mesenchymal transition in mouse melanoma model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Cadherins; Disease Models, Animal; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lipopolysaccharides; Male; Melanoma; Mice; Mice, Inbred C3H; NF-kappa B; Resveratrol; Signal Transduction; Skin Neoplasms; Snail Family Transcription Factors; Stilbenes; Transcription Factors | 2012 |
Proteomics analysis of human umbilical vein endothelial cells treated with resveratrol.
Topics: Acylation; Amino Acid Sequence; Antioxidants; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Molecular Sequence Data; Phosphorylation; Protein Processing, Post-Translational; Proteins; Proteomics; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2012 |
Lipase catalyzed acetylation of 3,5,4'-trihydroxystilbene: optimization and kinetics study.
Topics: Acetylation; Catalysis; Chromatography, High Pressure Liquid; Enzymes, Immobilized; Hot Temperature; Kinetics; Lipase; Magnetic Resonance Spectroscopy; Mass Spectrometry; Resveratrol; Stilbenes; Substrate Specificity | 2012 |
Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary.
Topics: Adult; Animals; Apoptosis; Female; Granulosa Cells; HeLa Cells; Humans; Middle Aged; Phosphoproteins; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Resveratrol attenuates obesity-associated peripheral and central inflammation and improves memory deficit in mice fed a high-fat diet.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diet, High-Fat; Fatty Liver; Glucose Tolerance Test; Inflammation; Insulin Resistance; Male; Maze Learning; Memory Disorders; Mice; Obesity; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Cytoprotection; Dinoprostone; Gene Expression Regulation; I-kappa B Proteins; Inflammation; Interleukin-1beta; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2012 |
Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients.
Topics: Antioxidants; beta-Globins; beta-Thalassemia; Cell Differentiation; Cell Proliferation; Erythroid Cells; Erythroid Precursor Cells; Fetal Hemoglobin; gamma-Globins; Gene Expression Regulation; Humans; K562 Cells; Oxidation-Reduction; Promoter Regions, Genetic; Protein Biosynthesis; Proteomics; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Tissue Donors; Transcription, Genetic | 2012 |
Development of HPLC fingerprint for species differentiation and quality assessment of Rhizoma Smilacis Glabrae.
Topics: Chromatography, High Pressure Liquid; Flavonols; Glycosides; Quercetin; Resveratrol; Rhizome; Shikimic Acid; Stilbenes; Tandem Mass Spectrometry | 2013 |
Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells.
Topics: Acetylcysteine; Benzamides; Cell Line; Chemokines; Cytokines; Defensins; Extracellular Signal-Regulated MAP Kinases; Glutathione; Humans; JNK Mitogen-Activated Protein Kinases; Naphthols; NF-kappa B; Niacinamide; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Protein Kinase C; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Stress, Mechanical; Toll-Like Receptors | 2012 |
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.
Topics: Aromatase; Aromatase Inhibitors; Binding Sites; Catalytic Domain; Computer Simulation; Enzyme Assays; Humans; Resveratrol; Stilbenes; Structure-Activity Relationship; Thiazoles | 2012 |
Dose-dependent effect of resveratrol on bladder cancer cells: chemoprevention and oxidative stress.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Cell Line, Tumor; Dinoprostone; Dose-Response Relationship, Drug; Humans; Neutrophils; Nitric Oxide; Oxidative Stress; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 2012 |
The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice.
Topics: Adiponectin; Animals; Antihypertensive Agents; Benzopyrans; Diastole; Diet, High-Fat; Dietary Carbohydrates; Hypertrophy, Left Ventricular; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Protein Processing, Post-Translational; Resveratrol; Stilbenes; Ventricular Function, Left | 2012 |
Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol.
Topics: Aging; Animals; Anti-Inflammatory Agents; Caloric Restriction; Energy Metabolism; Enzyme Activation; Enzyme Activators; Humans; Hypoglycemic Agents; Phosphodiesterase Inhibitors; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Effects of dietary resveratrol on the sleep-wake cycle in the non-human primate gray mouse lemur (Microcebus murinus).
Topics: Animals; Body Temperature; Cheirogaleidae; Circadian Rhythm; Dietary Supplements; Electroencephalography; Male; Photoperiod; Resveratrol; Sleep; Sleep Stages; Stilbenes | 2012 |
Resveratrol Inhibits respiratory syncytial virus-induced IL-6 production, decreases viral replication, and downregulates TRIF expression in airway epithelial cells.
Topics: Adaptor Proteins, Vesicular Transport; Antiviral Agents; Cell Line; Dexamethasone; Down-Regulation; Epithelial Cells; Humans; Interleukin-6; Interleukin-8; Protein Serine-Threonine Kinases; Respiratory Mucosa; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Respiratory System; Resveratrol; Ribavirin; Stilbenes; Virus Replication | 2012 |
Separation and identification of highly fluorescent compounds derived from trans-resveratrol in the leaves of Vitis vinifera infected by Plasmopara viticola.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Fluorescent Dyes; Glucosides; Isomerism; Mass Spectrometry; Peronospora; Phenanthrenes; Plant Diseases; Plant Extracts; Plant Leaves; Reference Standards; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2012 |
Sonic hedgehog signaling regulates Bcr-Abl expression in human chronic myeloid leukemia cells.
Topics: Antineoplastic Agents; Benzamides; Cell Survival; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Hedgehog Proteins; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Pyrimidines; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stilbenes; Up-Regulation | 2012 |
Analysis of in vitro chemoprevention of genotoxic damage by phytochemicals, as single agents or as combinations.
Topics: Anthocyanins; Antimutagenic Agents; Antioxidants; Catechin; Chlorogenic Acid; Diet; DNA Damage; HL-60 Cells; Humans; Micronucleus Tests; Mitomycin; Phytotherapy; Plants; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Cytokine-Induced Killer Cells; Cytotoxicity, Immunologic; Gene Expression Regulation, Leukemic; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-15; Interleukin-2; Intracellular Signaling Peptides and Proteins; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Ligands; NK Cell Lectin-Like Receptor Subfamily K; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor, Member 10c; Resveratrol; Stilbenes; Tumor Necrosis Factor Decoy Receptors | 2012 |
Resveratrol attenuates brain damage in a rat model of focal cerebral ischemia via up-regulation of hippocampal Bcl-2.
Topics: Animals; Apoptosis; Hippocampus; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Synaptic Transmission; Up-Regulation | 2012 |
MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line; Cell Line, Tumor; Cell Movement; Disease Progression; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Forkhead Transcription Factors; HEK293 Cells; Humans; Lung Neoplasms; Mice; Mice, SCID; MicroRNAs; NF-kappa B; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2013 |
Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice.
Topics: Adiposity; Animals; Cholesterol; Diet; Diet, High-Fat; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acid Synthases; Fatty Liver; Glucosephosphate Dehydrogenase; Hyperlipidemias; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphatidate Phosphatase; Resveratrol; Stilbenes; Triglycerides; Weight Gain | 2012 |
Resveratrol chemosensitizes breast cancer cells to melphalan by cell cycle arrest.
Topics: Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Female; Humans; Immunoprecipitation; Melphalan; Resveratrol; Stilbenes | 2012 |
Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis.
Topics: Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Cyclin B; Cyclin D; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Fas Ligand Protein; Histones; Humans; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
Resveratrol reverses temozolomide resistance by downregulation of MGMT in T98G glioblastoma cells by the NF-κB-dependent pathway.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Down-Regulation; Drug Combinations; Drug Resistance, Neoplasm; Glioblastoma; Humans; NF-kappa B; Resveratrol; Stilbenes; Temozolomide; Tumor Suppressor Proteins | 2012 |
Lipase-catalyzed modification of phenolic antioxidants.
Topics: Acylation; Alcaligenes; alpha-Tocopherol; Antioxidants; Bacterial Proteins; Biocatalysis; Candida; Esterification; Fungal Proteins; Hydrophobic and Hydrophilic Interactions; Lipase; Oxidation-Reduction; Resveratrol; Stereoisomerism; Stilbenes; Substrate Specificity | 2012 |
Dendrimers bind antioxidant polyphenols and cisplatin drug.
Topics: Antioxidants; Cisplatin; Curcumin; Dendrimers; Drug Delivery Systems; Genistein; Models, Molecular; Molecular Structure; Nylons; Polyethylene Glycols; Polyphenols; Resveratrol; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2012 |
Resveratrol inhibits KSHV reactivation by lowering the levels of cellular EGR-1.
Topics: Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Primers; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Gene Expression Profiling; Gene Expression Regulation, Viral; Genetic Vectors; HEK293 Cells; Herpesvirus 8, Human; Humans; Immediate-Early Proteins; Luciferases; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Trans-Activators; Virus Activation | 2012 |
Total syntheses of hopeanol and hopeahainol A empowered by a chiral Brønsted acid induced pinacol rearrangement.
Topics: Dimerization; Heterocyclic Compounds, 4 or More Rings; Methods; Phenols; Resveratrol; Stilbenes | 2012 |
Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan-polysaccharide rat model of Crohn's disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; Fibrosis; Ileum; Peptidoglycan; Polysaccharides; Procollagen; Rats; Rats, Inbred Lew; Resveratrol; Serum Albumin; Stilbenes | 2012 |
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Topics: Antioxidants; Cell Death; Cell Line; DNA Damage; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavanones; Genistein; Humans; Mutagenicity Tests; Resveratrol; Stilbenes | 2012 |
Enhancement of fluoride activity against Streptococcus mutans biofilms by a substance separated from Polygonum cuspidatum.
Topics: Biofilms; Drug Synergism; Emodin; Fallopia japonica; Fluorides; Humans; Hydrogen-Ion Concentration; Plant Extracts; Resveratrol; Stilbenes; Streptococcus mutans; Virulence Factors | 2012 |
Photochemical generation of a new, highly fluorescent compound from non-fluorescent resveratrol.
Topics: Fluorescent Dyes; Photons; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes; Ultraviolet Rays | 2012 |
Double-face activity of resveratrol in voluntary runners: assessment of DNA damage by comet assay.
Topics: Antioxidants; Case-Control Studies; Comet Assay; Deoxyguanosine; DNA Damage; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Male; Middle Aged; Oxidants; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Resveratrol; Running; Sedentary Behavior; Stilbenes | 2012 |
Effect of catch-up growth by various dietary patterns and resveratrol intervention on bone status.
Topics: Absorptiometry, Photon; Animals; Antioxidants; Body Weight; Bone and Bones; Bone Density; Caloric Restriction; Male; Malnutrition; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
The effects of resveratrol on porcine oocyte in vitro maturation and subsequent embryonic development after parthenogenetic activation and in vitro fertilization.
Topics: Animals; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; In Vitro Oocyte Maturation Techniques; Oocytes; Oogenesis; Parthenogenesis; Reactive Oxygen Species; Resveratrol; Stilbenes; Swine | 2012 |
Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway.
Topics: Alkaline Phosphatase; Animals; Apoptosis; Blotting, Western; Carbazoles; Cell Line, Tumor; Core Binding Factor Alpha 1 Subunit; Cytoprotection; Enzyme Activation; Enzyme Activators; Histone Deacetylase Inhibitors; Inflammation Mediators; Mice; NF-kappa B; Nitric Oxide; Osteoblasts; Osteocalcin; Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Transfection; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Resveratrol and its synthetic derivatives exert opposite effects on mesothelial cell-dependent angiogenesis via modulating secretion of VEGF and IL-8/CXCL8.
Topics: Cell Line; Culture Media, Conditioned; Epithelium; Humans; Interleukin-8; Neovascularization, Physiologic; Reactive Oxygen Species; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2012 |
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.
Topics: Age Factors; Aging; Animals; Body Weight; Curcumin; Drug Evaluation, Preclinical; Female; Longevity; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Models, Animal; Motor Activity; Oxaloacetic Acid; Pregnancy; Resveratrol; Sex Characteristics; Stilbenes; Tea; Triglycerides | 2013 |
Mitochondrial F(0) F(1) -ATP synthase is a molecular target of 3-iodothyronamine, an endogenous metabolite of thyroid hormone.
Topics: Animals; Binding Sites; Blotting, Western; Cattle; Kinetics; Mitochondria, Heart; Models, Molecular; Molecular Structure; Oxygen Consumption; Proton-Translocating ATPases; Resveratrol; Signal Transduction; Stilbenes; Thyronines | 2012 |
Extraordinary radical scavengers: 4-mercaptostilbenes.
Topics: Antioxidants; Biphenyl Compounds; Chromans; Free Radical Scavengers; Methanol; Molecular Structure; Picrates; Resveratrol; Solvents; Stilbenes; Sulfhydryl Compounds; Tocopherols | 2012 |
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity.
Topics: Autophagy; Cell Line, Tumor; Humans; Mitochondria; Neuroprotective Agents; Peptide Fragments; Prions; Resveratrol; Stilbenes | 2012 |
High-fructose corn syrup causes vascular dysfunction associated with metabolic disturbance in rats: protective effect of resveratrol.
Topics: Animals; Antioxidants; Aorta, Thoracic; Blood Glucose; Blood Pressure; Blotting, Western; Body Weight; Fructose; Insulin; Lipids; Male; NADPH Oxidases; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxides; Vascular Diseases; Vasoconstrictor Agents | 2012 |
Interactions of two O-phosphorylresveratrol derivatives with model membranes.
Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Membrane Permeability; Dimyristoylphosphatidylcholine; Drug Design; Humans; Lipid Bilayers; Male; Membranes, Artificial; Models, Molecular; Molecular Dynamics Simulation; Phosphorylation; Resveratrol; Stilbenes | 2012 |
Effects of resveratrol on enrichment of adipose-derived stem cells and their differentiation to osteoblasts in two-and three-dimensional cultures.
Topics: Adipose Tissue; Animals; Base Sequence; Bone and Bones; Cell Differentiation; Cells, Cultured; Culture Media; DNA Primers; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Resveratrol; Stem Cells; Stilbenes; Tissue Scaffolds | 2012 |
Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats.
Topics: Animals; Antioxidants; Energy Metabolism; Fatty Acids; Glucose; Glucose Tolerance Test; Heart; Hemodynamics; Isometric Contraction; Male; Muscle Strength; Muscle, Skeletal; Physical Endurance; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Antioxidant activity of trans-resveratrol toward hydroxyl and hydroperoxyl radicals: a quantum chemical and computational kinetics study.
Topics: Antioxidants; Free Radical Scavengers; Hydroxyl Radical; Kinetics; Molecular Structure; Oxidation-Reduction; Peroxides; Quantum Theory; Resveratrol; Stilbenes; Water | 2012 |
Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, Microcebus murinus.
Topics: Animal Feed; Animals; Blood Glucose; Caloric Restriction; Diet; Dietary Supplements; Glucose Tolerance Test; Insulin; Insulin Resistance; Lemur; Male; Oxygen Consumption; Resveratrol; Stilbenes; Time Factors | 2012 |
Resveratrol nanoparticle system improves dissolution properties and enhances the hepatoprotective effect of resveratrol through antioxidant and anti-inflammatory pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carbon Tetrachloride Poisoning; Drug Delivery Systems; Liver; Male; Nanoparticles; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes | 2012 |
In vitro and in vivo evaluation of resveratrol and 3,5-dihydroxy-4'-acetoxy-trans-stilbene in the treatment of human prostate carcinoma and melanoma.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; Melanoma; Mice; Mice, Nude; Prostatic Neoplasms; Resveratrol; Skin Neoplasms; Stilbenes; Time Factors; Treatment Outcome; Xenograft Model Antitumor Assays | 2013 |
Dual drug-eluting stent.
Topics: Animals; Cardiotonic Agents; Coronary Restenosis; Coronary Thrombosis; Delayed-Action Preparations; Drug-Eluting Stents; Humans; Quercetin; Resveratrol; Stilbenes | 2012 |
Grape variety related trans-resveratrol induction affects Aspergillus carbonarius growth and ochratoxin A biosynthesis.
Topics: Aspergillus; Food Microbiology; Fruit; Ochratoxins; Resveratrol; Stilbenes; Vitis | 2012 |
Endoplasmic reticulum stress in retinal vascular degeneration: protective role of resveratrol.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Disease Models, Animal; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Mice; Mice, Inbred C57BL; Oligopeptides; Protein Serine-Threonine Kinases; Regulatory Factor X Transcription Factors; Reperfusion Injury; Resveratrol; Retinal Degeneration; Retinal Ganglion Cells; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes; Transcription Factor CHOP; Transcription Factors; Tunicamycin; Up-Regulation; X-Box Binding Protein 1 | 2012 |
Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.
Topics: Animals; Antioxidants; Apoptosis; Cell Death; Cells, Cultured; Cytoprotection; Epithelial Cells; Fibroblasts; Humans; Inflammation; Interleukin-6; Mice; Mice, Knockout; Mitochondria; Myofibroblasts; NF-E2-Related Factor 2; Oxidative Stress; Paraquat; Reactive Oxygen Species; Response Elements; Resveratrol; Signal Transduction; Stilbenes; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2012 |
Reactive oxygen species facilitate translocation of hormone sensitive lipase to the lipid droplet during lipolysis in human differentiated adipocytes.
Topics: Acetylcysteine; Adipocytes; Adipose Tissue; Adult; Antioxidants; Biphenyl Compounds; Colforsin; Female; Humans; Lipids; Lipolysis; Middle Aged; Obesity; Onium Compounds; Phosphorylation; Primary Cell Culture; Protein Transport; Reactive Oxygen Species; Resveratrol; Serine; Signal Transduction; Sterol Esterase; Stilbenes | 2012 |
Sirt1 inhibits resistin expression in aortic stenosis.
Topics: Aged; Animals; Aortic Valve; Aortic Valve Stenosis; Binding Sites; Cells, Cultured; Chromatin Immunoprecipitation; Gene Expression Regulation; Genes, Reporter; Humans; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Middle Aged; Protein Binding; Resistin; Response Elements; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Transcription, Genetic | 2012 |
Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Binding Sites; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
The protective effect of resveratrol on islet insulin secretion and morphology in mice on a high-fat diet.
Topics: Animals; Antioxidants; Apoptosis; Cell Shape; Cells, Cultured; Cytoprotection; Diet, High-Fat; Drug Evaluation, Preclinical; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Resveratrol augments nitric oxide generation and causes store calcium release in chromaffin cells.
Topics: Adrenal Medulla; Animals; Antioxidants; Calcium; Cattle; Chromaffin Cells; Exocytosis; Fluorescent Dyes; Fura-2; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Resveratrol; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Stilbenes | 2012 |
Synergy study of the inhibitory potential of red wine polyphenols on vascular smooth muscle cell proliferation.
Topics: Animals; Catechin; Cell Proliferation; Drug Synergism; Gallic Acid; Muscle, Smooth, Vascular; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
The effect of dietary zinc--and polyphenols intake on DMBA-induced mammary tumorigenesis in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Carcinogens; Dietary Supplements; Female; Genistein; Mammary Neoplasms, Animal; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Zinc | 2012 |
Resveratrol downregulates acute pulmonary thromboembolism-induced pulmonary artery hypertension via p38 mitogen-activated protein kinase and monocyte chemoattractant protein-1 signaling in rats.
Topics: Animals; Blotting, Western; Chemokine CCL2; Down-Regulation; Enzyme Inhibitors; Fluorescent Antibody Technique; Hypertension, Pulmonary; Imidazoles; Immunohistochemistry; Indicators and Reagents; Male; p38 Mitogen-Activated Protein Kinases; Pulmonary Embolism; Pyridines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes | 2012 |
[Improving the dissolution rate of poorly water-soluble resveratrol by the ordered mesoporous silica].
Topics: Drug Carriers; Drug Compounding; Drug Delivery Systems; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Porosity; Resveratrol; Silicon Dioxide; Solubility; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Ray Diffraction | 2012 |
Effects of resveratrol on the ultrastructure of Botrytis cinerea conidia and biological significance in plant/pathogen interactions.
Topics: Botrytis; Host-Pathogen Interactions; Plant Diseases; Resveratrol; Spores, Fungal; Stilbenes; Vitis | 2012 |
Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers.
Topics: Acetylation; Algorithms; Amino Acid Motifs; Antineoplastic Agents; Apoptosis; Autophagy; Computational Biology; Cyclin-Dependent Kinase 2; Enzyme Activation; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Longevity; Mass Spectrometry; Methylation; Phosphoproteins; Phosphorylation; Protein Interaction Mapping; Protein Interaction Maps; Proteomics; Resveratrol; Signal Transduction; Spermidine; Stilbenes; Ubiquitination | 2012 |
Metabonomic variations associated with AOM-induced precancerous colorectal lesions and resveratrol treatment.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colorectal Neoplasms; Male; Metabolome; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Alternaria sp. MG1, a resveratrol-producing fungus: isolation, identification, and optimal cultivation conditions for resveratrol production.
Topics: Alternaria; Antioxidants; Culture Media; DNA, Fungal; Endophytes; Fallopia japonica; Fermentation; Molecular Sequence Data; Resveratrol; Sequence Analysis, DNA; Stilbenes; Vitis | 2012 |
Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Alkylating; Calcium-Binding Proteins; Cell Line, Tumor; Dacarbazine; Drug Synergism; Drug Therapy, Combination; Female; Glioblastoma; Humans; Mice; Mice, Inbred BALB C; Mice, Knockout; Mice, Nude; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Temozolomide; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2012 |
Resveratrol and piperine enhance radiosensitivity of tumor cells.
Topics: Alkaloids; Anticarcinogenic Agents; Apoptosis; Benzodioxoles; Blotting, Western; Colonic Neoplasms; Humans; Melanoma, Experimental; Membrane Potential, Mitochondrial; Oxidation-Reduction; Piper nigrum; Piperidines; Polyunsaturated Alkamides; Radiation Tolerance; Radiation-Sensitizing Agents; Radiation, Ionizing; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2012 |
Curcumin and resveratrol in combination modulates benzo(a)pyrene-induced genotoxicity during lung carcinogenesis.
Topics: Animals; Antimutagenic Agents; Apoptosis; Benzo(a)pyrene; Carcinogens; Curcumin; Disease Models, Animal; Drug Therapy, Combination; Lung; Lung Neoplasms; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitosis; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents endothelial cells injury in high-dose interleukin-2 therapy against melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Endothelial Cells; Female; Immunotherapy; Interleukin-2; Killer Cells, Lymphokine-Activated; Lung Neoplasms; Melanoma; Mice; Neoplasm Transplantation; Resveratrol; Stilbenes; T-Lymphocytes, Regulatory | 2012 |
Distribution of resveratrol metabolites in liver, adipose tissue, and skeletal muscle in rats fed different doses of this polyphenol.
Topics: Adipose Tissue; Animals; Humans; Liver; Male; Metagenome; Muscle, Skeletal; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents impairment in activation of retinoic acid receptors and MAP kinases in the embryos of a rodent model of diabetic embryopathy.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Fetal Diseases; Mitogen-Activated Protein Kinases; Neural Tube Defects; Pregnancy; Pregnancy in Diabetics; Rats; Receptors, Retinoic Acid; Resveratrol; Stilbenes | 2012 |
Resveratrol protects H9c2 embryonic rat heart derived cells from oxidative stress by inducing autophagy: role of p38 mitogen-activated protein kinase.
Topics: Animals; Apoptosis; Autophagy; Cell Death; Cell Survival; Cells, Cultured; Heart; Hydrogen Peroxide; Imidazoles; L-Lactate Dehydrogenase; Myocardium; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Resveratrol; Stilbenes; Up-Regulation | 2012 |
Drug repositioning through incomplete bi-cliques in an integrated drug-target-disease network.
Topics: Algorithms; Amino Acid Sequence; Binding Sites; Chemistry, Pharmaceutical; Computational Biology; Databases, Factual; Drug Delivery Systems; Drug Repositioning; Gene Regulatory Networks; Humans; Molecular Conformation; Molecular Sequence Data; Pharmaceutical Preparations; Quercetin; Resveratrol; Sequence Homology, Amino Acid; Software; Stilbenes | 2012 |
Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Down-Regulation; Mesenchymal Stem Cells; Mice; Niacinamide; Nuclear Receptor Co-Repressor 1; Oligonucleotides, Antisense; Osteogenesis; PPAR gamma; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Distinct sulfonation activities in resveratrol-sensitive and resveratrol-insensitive human glioblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Arylsulfotransferase; Blotting, Western; Brain Neoplasms; Chromatography, High Pressure Liquid; Drug Resistance, Neoplasm; Flow Cytometry; Glioblastoma; Humans; Immunoenzyme Techniques; Mass Spectrometry; Neoplasm Grading; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Sulfonic Acids; Sulfotransferases; Tissue Array Analysis; Tumor Cells, Cultured | 2012 |
Resveratrol inhibits reproductive toxicity induced by deoxynivalenol.
Topics: Animals; Female; Reproduction; Resveratrol; Stilbenes; Swine; Trichothecenes | 2012 |
Chronic resveratrol administration has beneficial effects in experimental model of type 2 diabetic rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hyperglycemia; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2012 |
Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast.
Topics: Adipocytes; Animals; beta Catenin; Biomarkers; Blotting, Western; Calcification, Physiologic; Cell Differentiation; Cell Line; Embryonic Stem Cells; Enzyme Activation; Fluorescent Antibody Technique; Gene Expression Regulation; Gene Silencing; Insulin; Lipid Metabolism; Mice; Osteoblasts; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription, Genetic | 2012 |
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation.
Topics: Acetylation; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; DNA Methylation; Genes, Tumor Suppressor; Humans; Immunoprecipitation; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; STAT3 Transcription Factor; Stilbenes | 2012 |
Why research on resveratrol-mediated cardioprotection should not decelerate.
Topics: Animals; Cardiotonic Agents; Heart; Heart Diseases; Humans; Research Design; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits neointimal formation after arterial injury through an endothelial nitric oxide synthase-dependent mechanism.
Topics: Administration, Oral; Animals; Aorta; Cardiovascular Agents; Carotid Arteries; Carotid Artery Injuries; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Femoral Artery; Gene Expression Regulation; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Neointima; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Time Factors; Vascular System Injuries | 2012 |
Induced growth of BG-1 ovarian cancer cells by 17β-estradiol or various endocrine disrupting chemicals was reversed by resveratrol via downregulation of cell cycle progression.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Endocrine Disruptors; Estradiol; Female; Humans; Ovarian Neoplasms; Resveratrol; Stilbenes | 2012 |
The flavonoid resveratrol suppresses growth of human malignant pleural mesothelioma cells through direct inhibition of specificity protein 1.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Humans; Inhibitor of Apoptosis Proteins; Membrane Proteins; Mesothelioma; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Pleural Neoplasms; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA, Messenger; Sp1 Transcription Factor; Stilbenes; Survivin; Transplantation, Heterologous | 2012 |
Role of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.
Topics: Acrylamides; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; AMP-Activated Protein Kinases; Animals; Blotting, Western; Carbazoles; Cell Line, Tumor; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HEK293 Cells; Hep G2 Cells; Humans; Mice; Mice, Knockout; Models, Biological; Mutation; NAD; Niacinamide; Phosphorylation; Piperidines; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
Complete blood count and acetylcholinesterase activity of lymphocytes of demyelinated and ovariectomized rats treated with resveratrol.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Demyelinating Diseases; Enzyme Inhibitors; Ethidium; Female; Lymphocytes; Ovariectomy; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Premature mitochondrial senescence and related ultrastructural changes during lung carcinogenesis modulation by curcumin and resveratrol.
Topics: Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Cellular Senescence; Curcumin; Disease Models, Animal; Drug Therapy, Combination; Lung Neoplasms; Male; Mice; Mitochondria; Pulmonary Alveoli; Resveratrol; Stilbenes | 2012 |
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Enzyme Activation; Hepatocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Muscle, Skeletal; NAD; Protein Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2012 |
SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence.
Topics: Animals; Cells, Cultured; Cellular Senescence; Enzyme Inhibitors; Gene Silencing; Hyperglycemia; Male; Mesangial Cells; Niacinamide; Rats; Rats, Wistar; Resveratrol; Sirolimus; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases; Vitamin B Complex | 2012 |
Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; beta-Galactosidase; Blotting, Western; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Assays; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
[Trimethoxystilbene and its effects on the proliferation and apoptosis of PASMCs].
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Male; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Cells, Cultured; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Ganglia, Spinal; Gene Expression Regulation; Green Fluorescent Proteins; Hyperalgesia; Male; Membrane Potentials; Mice; Mitochondrial Diseases; Mitochondrial Membranes; Mutation; Nerve Fibers, Myelinated; Neurites; Oxygen Consumption; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Stimulation; Rats; Rats, Sprague-Dawley; Reaction Time; Resveratrol; RNA-Binding Proteins; Sensory Receptor Cells; Signal Transduction; Stilbenes; Transcription Factors; Transduction, Genetic | 2012 |
The effect of the red wine polyphenol resveratrol on a rat model of biliary obstructed cholestasis: involvement of anti-apoptotic signalling, mitochondrial biogenesis and the induction of autophagy.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Autophagy; bcl-2-Associated X Protein; Bilirubin; Caspase 3; Catalase; Cholestasis, Extrahepatic; DNA Copy Number Variations; DNA, Mitochondrial; Liver; Male; Microtubule-Associated Proteins; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Red wine extract protects against oxidative-stress-induced endothelial senescence.
Topics: Antioxidants; beta-Galactosidase; Cells, Cultured; Cellular Senescence; DNA Damage; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Polyphenols; Prostaglandins; Resveratrol; Sirtuin 1; Stilbenes; tert-Butylhydroperoxide; Wine | 2012 |
SIRT1 attenuates palmitate-induced endoplasmic reticulum stress and insulin resistance in HepG2 cells via induction of oxygen-regulated protein 150.
Topics: Endoplasmic Reticulum Stress; Forkhead Box Protein O1; Forkhead Transcription Factors; Hep G2 Cells; HSP70 Heat-Shock Proteins; Humans; Insulin Resistance; Palmitates; Proteins; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Caveolin-3 is involved in the protection of resveratrol against high-fat-diet-induced insulin resistance by promoting GLUT4 translocation to the plasma membrane in skeletal muscle of ovariectomized rats.
Topics: Animals; Caveolin 3; Cell Membrane; Diet, High-Fat; Estrogen Receptor alpha; Female; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Insulin; Insulin Resistance; Muscle Fibers, Skeletal; Muscle, Skeletal; Ovariectomy; Protective Agents; Protein Transport; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
So, you want to live to 120? The genie in the bottle.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Humans; Resveratrol; Stilbenes | 2012 |
Resveratrol suppresses 4-hydroxyestradiol-induced transformation of human breast epithelial cells by blocking IκB kinaseβ-NF-κB signalling.
Topics: Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Epithelial Cells; Estrogens, Catechol; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Humans; I-kappa B Kinase; Mammary Glands, Human; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.
Topics: Aerobiosis; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Silencing; Glucose; Glycolysis; Humans; Lactic Acid; Pyruvate Kinase; Resveratrol; RNA, Messenger; Stilbenes; TOR Serine-Threonine Kinases | 2012 |
Penetration of resveratrol into bovine aortic endothelial cells (BAEC): a possible passive diffusion.
Topics: Animals; Antioxidants; Aorta; Biological Transport, Active; Cattle; Cell Membrane; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Cytosol; Endothelial Cells; Intracellular Space; Proteins; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes; Temperature | 2012 |
Piceatannol, a resveratrol derivative, promotes glucose uptake through glucose transporter 4 translocation to plasma membrane in L6 myocytes and suppresses blood glucose levels in type 2 diabetic model db/db mice.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Blood Glucose; Cell Line; Cell Membrane; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Activation; Glucose; Glucose Transporter Type 4; Mice; Molecular Imaging; Muscle Cells; Protein Kinases; Rats; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents TNFα-induced suppression of adiponectin expression via PPARγ activation in 3T3-L1 adipocytes.
Topics: Adipocytes; Adiponectin; Animals; Anti-Inflammatory Agents; Cell Line; Mice; PPAR gamma; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Resveratrol protects cortical neurons against microglia-mediated neuroinflammation.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Inflammation; Interleukin-1beta; Lipopolysaccharides; Microglia; Neurons; Neuroprotective Agents; Nitric Oxide; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Resveratrol stimulates cortisol biosynthesis by activating SIRT-dependent deacetylation of P450scc.
Topics: Antioxidants; Cholesterol Side-Chain Cleavage Enzyme; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Lysine; Mitochondria; Mutagenesis; Mutation; Protein Processing, Post-Translational; Resveratrol; RNA Interference; Sirtuin 1; Sirtuin 3; Sirtuins; Stilbenes | 2012 |
In this issue of the International Reviews of Immunology.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hepatitis C; Humans; Hypersensitivity; Immune System; Models, Immunological; Myeloid Cells; Neoplasms; Resveratrol; Stilbenes; Viral Hepatitis Vaccines | 2012 |
A selective aryl hydrocarbon receptor modulator 3,3'-Diindolylmethane inhibits gastric cancer cell growth.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drug Interactions; Humans; Indoles; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Stomach Neoplasms | 2012 |
A dietary resveratrol-rich grape extract prevents the developing of atherosclerotic lesions in the aorta of pigs fed an atherogenic diet.
Topics: Animals; Aorta; Atherosclerosis; Diet, Atherogenic; Disease Models, Animal; Female; Humans; In Vitro Techniques; Male; Plant Extracts; Resveratrol; Stilbenes; Swine; Swine, Miniature; Vitis | 2012 |
Resveratrol-loaded solid lipid nanoparticles versus nanostructured lipid carriers: evaluation of antioxidant potential for dermal applications.
Topics: Analysis of Variance; Animals; Antioxidants; Cell Survival; Dermis; Drug Carriers; Epidermis; Flow Cytometry; Humans; Lipids; Nanoparticles; Particle Size; Rats; Resveratrol; Stilbenes | 2012 |
Mycoflora and ochratoxin a control in wheat grain using natural extracts obtained from wine industry by-products.
Topics: Antifungal Agents; Aspergillus; Butylated Hydroxytoluene; Fusarium; Grape Seed Extract; Mycotoxins; Ochratoxins; Penicillium; Plant Diseases; Plant Extracts; Resveratrol; Stilbenes; Triticum; Vitis; Wine | 2012 |
Resveratrol induces apoptosis associated with mitochondrial dysfunction in bladder carcinoma cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Drug Screening Assays, Antitumor; Enzyme Activation; Humans; Membrane Potential, Mitochondrial; Mice; Reactive Oxygen Species; Resveratrol; Stilbenes; Urinary Bladder Neoplasms | 2012 |
Dietary resveratrol increases the expression of hepatic 7α-hydroxylase and ameliorates hypercholesterolemia in high-fat fed C57BL/6J mice.
Topics: Animals; Cholesterol 7-alpha-Hydroxylase; Diet, High-Fat; Dietary Supplements; Hep G2 Cells; Humans; Hypercholesterolemia; Hypolipidemic Agents; Liver; Liver X Receptors; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Resveratrol; Stilbenes; Transcription, Genetic; Transcriptional Activation | 2012 |
Salutary effect of resveratrol on sepsis-induced myocardial depression.
Topics: Animals; Cardiomyopathies; Cecum; Down-Regulation; Edema; Gene Expression; Heart Failure; Ligation; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Random Allocation; Resveratrol; Sepsis; Stilbenes; Trans-Activators; Transcription Factors; Vasodilator Agents | 2012 |
In vino veritas? Pliny the Elder.
Topics: Animals; Heart Failure; Male; Myocardial Contraction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Sepsis; Stilbenes; Trans-Activators; Transcription Factors; Vasodilator Agents | 2012 |
Resveratrol exerts dosage and duration dependent effect on human mesenchymal stem cell development.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Differentiation; Cell Division; Cell Proliferation; Cells, Cultured; Cellular Senescence; Dose-Response Relationship, Drug; Gene Expression; Humans; Mesenchymal Stem Cells; Osteogenesis; Resveratrol; S Phase; Stilbenes | 2012 |
Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats.
Topics: Animals; Ascorbic Acid; Blood Glucose; Body Weight; Catalase; Eating; Fructose; Glucose Tolerance Test; Glutathione; Insulin; Insulin Resistance; Liver; Male; Metabolic Syndrome; Metformin; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Triglycerides; Uric Acid | 2012 |
Polyphenolic acetylcholinesterase inhibitors from Hopea chinensis.
Topics: Benzofurans; Chemical Fractionation; Cholinesterase Inhibitors; Computational Biology; Dipterocarpaceae; Enzyme Assays; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Molecular Conformation; Plant Bark; Plant Stems; Polyphenols; Resveratrol; Stilbenes | 2012 |
Resveratrol protects adult cardiomyocytes against oxidative stress mediated cell injury.
Topics: Animals; Antioxidants; Cardiotonic Agents; Catalase; Cell Survival; Cytoprotection; Glutathione Peroxidase; Hydrogen Peroxide; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2012 |
Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol.
Topics: Arsenic; Base Sequence; Blotting, Western; Cell Line, Transformed; DNA Primers; Dose-Response Relationship, Drug; ErbB Receptors; Humans; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2012 |
Resveratrol induces downregulation of DNA repair genes in MCF-7 human breast cancer cells.
Topics: Angiogenesis Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Repair; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Resveratrol; Stilbenes | 2013 |
p38 inhibitor SB203580 sensitizes the resveratrol-induced apoptosis in human lung adenocarcinoma (A549) cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Survival; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes | 2012 |
Multiple anti-inflammatory pathways triggered by resveratrol lead to amelioration of staphylococcal enterotoxin B-induced lung injury.
Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Apoptosis; Cytokines; Endothelial Cells; Enterotoxins; Female; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Pneumonia; Resveratrol; Sirtuin 1; Spleen; Stilbenes; T-Lymphocytes; Transcription Factor RelA | 2012 |
Long-term resveratrol consumption protects ovariectomized rats chronically treated with D-galactose from developing memory decline without effects on the uterus.
Topics: Animals; Antioxidants; Body Weight; Eating; Emotions; Estradiol; Female; Galactose; Glutathione Peroxidase; Hippocampus; Maze Learning; Memory; Memory Disorders; Motor Activity; Neurons; Ovariectomy; Oxidation-Reduction; Protein Carbonylation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Uterus | 2012 |
Activation of peroxisome proliferator-activated receptor-γ coactivator 1α ameliorates mitochondrial dysfunction and protects podocytes from aldosterone-induced injury.
Topics: Aldosterone; Animals; Apoptosis; Cell Line; Cytoprotection; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation; Genes, Reporter; Kidney Diseases; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Mitochondria; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Podocytes; Promoter Regions, Genetic; Receptors, Mineralocorticoid; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Resveratrol; RNA Interference; Sirtuin 1; Stilbenes; Time Factors; Trans-Activators; Transcription Factors; Transfection | 2012 |
Hydroxyl radical reaction with trans-resveratrol: initial carbon radical adduct formation followed by rearrangement to phenoxyl radical.
Topics: Carbon; Electron Transport; Hydroxyl Radical; Isomerism; Models, Molecular; Phenols; Photolysis; Protons; Quantum Theory; Resveratrol; Spectrophotometry; Stilbenes | 2012 |
Resveratrol effect on osteogenic differentiation of rat and human adipose derived stem cells in a 3-D culture environment.
Topics: Adipose Tissue; Animals; Cell Culture Techniques; Cell Differentiation; Child; Collagen; Dose-Response Relationship, Drug; Extracellular Matrix; Humans; Male; Minerals; Osteogenesis; Polyesters; Rats; Resveratrol; Stem Cells; Stilbenes; Tissue Scaffolds | 2012 |
Protective effect of ferulic acid and resveratrol against alloxan-induced diabetes in mice.
Topics: Active Transport, Cell Nucleus; Animals; Antioxidants; Biomarkers; Cell Nucleus; Coumaric Acids; Diabetes Mellitus, Experimental; Disease Progression; Kidney; Lipid Peroxidation; Liver; Mice; NF-kappa B; Pancreas; Resveratrol; Stilbenes | 2012 |
Resveratrol helps recovery from fatty liver and protects against hepatocellular carcinoma induced by hepatitis B virus X protein in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinoma, Hepatocellular; Disease Models, Animal; Fatty Liver; Glutathione; Humans; Immunoenzyme Techniques; Liver Neoplasms, Experimental; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Trans-Activators; Tumor Cells, Cultured; Viral Regulatory and Accessory Proteins | 2012 |
Effect of resveratrol on scopolamine-induced cognitive impairment in mice.
Topics: Animals; Avoidance Learning; Behavior, Animal; Cognition Disorders; Injections, Intraperitoneal; Maze Learning; Memory Disorders; Mice; Motor Activity; Muscarinic Antagonists; Neuroprotective Agents; Reaction Time; Resveratrol; Scopolamine; Stilbenes; Treatment Outcome | 2012 |
PHBV/PCL microparticles for controlled release of resveratrol: physicochemical characterization, antioxidant potential, and effect on hemolysis of human erythrocytes.
Topics: Antioxidants; Calorimetry, Differential Scanning; Drug Carriers; Erythrocytes; Hemolysis; Humans; Microscopy, Electron, Scanning; Particle Size; Polyesters; Resveratrol; Stilbenes; Thermogravimetry | 2012 |
[Study on human UDP-glucuronosyltransferase (UGT) isoforms involved in in vitro metabolism of trans-resveratrol].
Topics: Glucuronic Acid; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Resveratrol; Stilbenes | 2012 |
Physicochemical properties and antioxidant activities of Korean traditional alcoholic beverage, yakju, enriched with mulberry.
Topics: Alcoholic Beverages; Anthocyanins; Antioxidants; Benzothiazoles; Biphenyl Compounds; Chemical Phenomena; Fermentation; Flavonoids; Food Handling; Fruit; Morus; Picrates; Polyphenols; Republic of Korea; Resveratrol; Stilbenes; Sulfonic Acids | 2012 |
Resveratrol-sensitized UVA induced apoptosis in human keratinocytes through mitochondrial oxidative stress and pore opening.
Topics: Apoptosis; HEK293 Cells; Humans; Keratinocytes; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Resveratrol; Stilbenes; Ultraviolet Rays | 2012 |
Resveratrol induces antioxidant defence via transcription factor Yap1p.
Topics: Adipocytes; Antioxidants; Cell Line; Gene Expression Regulation, Fungal; Humans; Oxidative Stress; Protein Transport; Reactive Oxygen Species; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stilbenes; Transcription Factors | 2012 |
Resveratrol prevents nicotine-induced teratogenesis in cultured mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; bcl-X Protein; Caspase 3; Embryo, Mammalian; Female; Gene Expression Regulation, Developmental; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Nicotine; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Teratogens | 2012 |
Inhibitory effect of gnetin C, a resveratrol dimer from melinjo (Gnetum gnemon), on tyrosinase activity and melanin biosynthesis.
Topics: Animals; Benzofurans; Cell Survival; Enzyme Inhibitors; Gnetum; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2012 |
Sirt-1 is required for the inhibition of apoptosis and inflammatory responses in human tenocytes.
Topics: Acetylation; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Proliferation; Cell Survival; Cells, Cultured; Enzyme Activation; Enzyme Activators; Gene Knockdown Techniques; Humans; Interleukin-1beta; Mitochondria; NF-kappa B; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Processing, Post-Translational; Proteolysis; Proto-Oncogene Proteins c-akt; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Tendinopathy; Tendons; Tumor Suppressor Protein p53 | 2012 |
Impairment of tumor-initiating stem-like property and reversal of epithelial-mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Epithelial Cells; Epithelial-Mesenchymal Transition; Gingiva; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Isoenzymes; Mice; Mice, Nude; Neoplastic Stem Cells; Resveratrol; Retinal Dehydrogenase; Stilbenes; Xenograft Model Antitumor Assays | 2012 |
Suppressing effect of resveratrol on the migration and invasion of human metastatic lung and cervical cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; Female; HeLa Cells; Humans; Lung Neoplasms; Male; Matrix Metalloproteinase 9; Neoplasm Metastasis; NF-kappa B; Reactive Oxygen Species; Resveratrol; Stilbenes; Transcription Factor AP-1; Transcriptional Activation; Uterine Cervical Neoplasms | 2012 |
Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor.
Topics: Animals; Cell Line; Cytokines; Enzyme Inhibitors; Flavonoids; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-kappa B; Nitric Oxide; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
Tyrosinase inhibition constituents from the roots of Morus australis.
Topics: Agaricales; Benzofurans; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Monophenol Monooxygenase; Morus; Phenols; Plant Extracts; Plant Roots; Plant Stems; Pyrones; Resveratrol; Stilbenes | 2012 |
Kinetic aspects of ultrasound-accelerated lipase catalyzed acetylation and optimal synthesis of 4'-acetoxyresveratrol.
Topics: Acetylation; Biocatalysis; Candida; Kinetics; Lipase; Models, Chemical; Resveratrol; Stilbenes; Ultrasonics | 2013 |
Mango fruit peel and flesh extracts affect adipogenesis in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Cell Nucleus; Fruit; Mangifera; Mice; Plant Extracts; Resveratrol; Species Specificity; Stilbenes | 2012 |
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy.
Topics: Animals; Antioxidants; Autophagy; Bronchi; Cell Line; Epithelial Cells; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Lung; Male; Mice; Mice, Inbred BALB C; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Resveratrol; Sirtuin 1; Smoking; Stilbenes | 2012 |
Resveratrol-poor red wines modulate SIRT1 in human renal cells.
Topics: AMP-Activated Protein Kinases; Basic Helix-Loop-Helix Transcription Factors; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Humans; Kidney Tubules; Plant Extracts; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Vitis; Wine | 2012 |
Effect of resveratrol on treatment of bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Cell Count; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Male; Malondialdehyde; Oxidative Stress; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Effects of trimethoxystilbene on proliferation and apoptosis of pulmonary artery smooth muscle cells.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Flow Cytometry; Humans; Hypertension; Inflammation; Male; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
Resveratrol preconditioning modulates inflammatory response in the rat hippocampus following global cerebral ischemia.
Topics: Animals; Brain Ischemia; Hippocampus; Inflammation Mediators; Ischemic Preconditioning; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Tyrosine nitration of voltage-dependent anion channels in cardiac ischemia-reperfusion: reduction by peroxynitrite scavenging.
Topics: Animals; Guinea Pigs; Mass Spectrometry; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Resveratrol; Stilbenes; Superoxides; Tyrosine; Voltage-Dependent Anion Channels | 2012 |
Resveratrol regulates N-methyl-D-aspartate receptor expression and suppresses neuroinflammation in morphine-tolerant rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Gene Expression Regulation; Inflammation; Male; Morphine; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Resveratrol; Stilbenes | 2012 |
Resveratrol ameliorates diabetes-related metabolic changes via activation of AMP-activated protein kinase and its downstream targets in db/db mice.
Topics: Adiponectin; AMP-Activated Protein Kinases; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Dietary Supplements; Dyslipidemias; Glucose Transporter Type 4; Glycated Hemoglobin; Glycogen; Insulin; Insulin Secretion; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Resveratrol; Rosiglitazone; Stilbenes; Thiazolidinediones; Triglycerides | 2012 |
Resveratrol and quercetin interact to inhibit neointimal hyperplasia in mice with a carotid injury.
Topics: Animals; Antioxidants; Carotid Artery Injuries; Cell Proliferation; Chemotaxis; Drug Interactions; Endothelial Cells; Endothelium, Vascular; Female; Hyperplasia; Inflammation; Mice; Monocytes; Neointima; Quercetin; Resveratrol; Stilbenes; Thromboxane B2 | 2012 |
Resveratrol reduces steroidogenesis in rat ovarian theca-interstitial cells: the role of inhibition of Akt/PKB signaling pathway.
Topics: Animals; Blotting, Western; Cells, Cultured; Female; Mass Spectrometry; Ovary; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Resveratrol; Steroids; Stilbenes; Theca Cells | 2012 |
TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells.
Topics: Animals; Antioxidants; Apoptosis; Boranes; Carbonates; Caspase 3; Caspase 7; Cell Line; Cell Survival; Cycloheximide; Dose-Response Relationship, Drug; Epithelial Cells; Heme Oxygenase-1; Intestinal Mucosa; Mice; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sodium Nitrite; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
Muscle mitochondria and insulin resistance: a human perspective.
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Mitochondria, Muscle; Resveratrol; Stilbenes | 2012 |
Resveratrol still has something to say about aging!
Topics: Aging; Antioxidants; Humans; Polyphenols; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Vitis; Wine | 2012 |
The effect of resveratrol on FoxO1 expression in kidneys of diabetic nephropathy rats.
Topics: Animals; Antioxidants; Body Weight; Catalase; Collagen Type IV; Diabetic Nephropathies; Fibronectins; Forkhead Transcription Factors; Gene Expression Regulation; Kidney; Male; Nerve Tissue Proteins; Organ Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
ε-Viniferin is more effective than its monomer resveratrol in improving the functions of vascular endothelial cells and the heart.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Benzofurans; Blood Pressure; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Male; Myocardium; Nitric Oxide; Organ Size; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes; Swine | 2012 |
Synergistic effects of prenatal hypoxia and postnatal high-fat diet in the development of cardiovascular pathology in young rats.
Topics: Animals; Blood Pressure; Body Weight; Diet, High-Fat; Female; Fetal Growth Retardation; Heart; Heart Rate; Hypoxia; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Association of SIRT1 expression with shear stress induced endothelial progenitor cell differentiation.
Topics: Acetylation; Androstadienes; Biomarkers; Biomechanical Phenomena; Cell Differentiation; Cell Lineage; Cell Shape; Cells, Cultured; Endothelial Cells; Fetal Blood; Gene Expression Regulation; Histones; Humans; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphorylation; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stem Cells; Stilbenes; Stress, Mechanical; Time Factors; Wortmannin | 2012 |
Resveratrol induces nuclear factor-κB activity in human cardiac cells.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cells, Cultured; Humans; Male; Mice; Myocytes, Cardiac; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Effect of resveratrol and modulation of cytokine production on human periodontal ligament cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Inflammation Mediators; Interleukin-12; Interleukin-1beta; Interleukin-8; Lipopolysaccharides; Nitric Oxide; Periodontal Ligament; Periodontitis; Porphyromonas gingivalis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Apoptotic effects of resveratrol, a grape polyphenol, on imatinib-sensitive and resistant K562 chronic myeloid leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Caspase 7; Cell Growth Processes; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potential, Mitochondrial; Piperazines; Pyrimidines; Resveratrol; Stilbenes | 2012 |
Immobilization of laccase for oxidative coupling of trans-resveratrol and its derivatives.
Topics: Adsorption; Antioxidants; Enzymes, Immobilized; Fungal Proteins; Hydrogen-Ion Concentration; Laccase; Oxidative Coupling; Resveratrol; Silicon Dioxide; Stilbenes; Temperature; Trametes | 2012 |
Resveratrol and some glucosyl, glucosylacyl, and glucuronide derivatives reduce Escherichia coli O157:H7, Salmonella Typhimurium, and Listeria monocytogenes Scott A adhesion to colonic epithelial cell lines.
Topics: Anti-Bacterial Agents; Bacterial Adhesion; Caco-2 Cells; Colony Count, Microbial; Escherichia coli O157; Food Contamination; Food Microbiology; HT29 Cells; Humans; Interleukin-8; Listeria monocytogenes; Resveratrol; Salmonella typhimurium; Stilbenes | 2012 |
A preliminary study of presence of resveratrol in skins and pulps of European and Japanese plum cultivars.
Topics: Chromatography, Liquid; Europe; Fruit; Japan; Prunus; Resveratrol; Species Specificity; Stilbenes; Tandem Mass Spectrometry | 2012 |
Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in lymphoma nude mice by heme oxygenase-1 induction.
Topics: Animals; Apoptosis; Burkitt Lymphoma; Cell Line, Tumor; Doxorubicin; Enzyme Induction; Heme Oxygenase-1; Humans; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Myocytes, Cardiac; Random Allocation; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2012 |
Synthesis and evaluation of water-soluble resveratrol and piceatannol via BGLation.
Topics: Glycerol; Mitochondria; Resveratrol; Solubility; Stilbenes; Water | 2012 |
Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.
Topics: Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; BRCA1 Protein; Female; Genistein; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Ovariectomy; Phytoestrogens; Resveratrol; Stilbenes; Survival Rate; Tumor Suppressor Protein p53 | 2012 |
Polyphenols sensitization potentiates susceptibility of MCF-7 and MDA MB-231 cells to Centchroman.
Topics: Antioxidants; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Shape; Centchroman; Curcumin; Drug Screening Assays, Antitumor; Drug Synergism; Estrogen Receptor alpha; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors; Tumor Suppressor Protein p53 | 2012 |
Resveratrol treatment reduces cardiac progenitor cell dysfunction and prevents morpho-functional ventricular remodeling in type-1 diabetic rats.
Topics: Actins; Animals; Apoptosis; Blood Glucose; Body Weight; Calcium Signaling; Cell Count; Coculture Techniques; Diabetes Mellitus, Type 1; Endothelial Cells; Hemodynamics; HMGB1 Protein; Intracellular Space; Male; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Resveratrol; Stem Cells; Stilbenes; Ventricular Remodeling | 2012 |
Regioselective hydroxylation of trans-resveratrol via inhibition of tyrosinase from Streptomyces avermitilis MA4680.
Topics: Catechol Oxidase; Catechols; Hydroxylation; Melanins; Monophenol Monooxygenase; Mutation; Plasmids; Reducing Agents; Resveratrol; Stereoisomerism; Stilbenes; Streptomyces | 2012 |
Antioxidant combinations protect oral fibroblasts against metal-induced toxicity.
Topics: Antioxidants; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Copper; Coumaric Acids; Curcumin; Dental Materials; DNA; Dose-Response Relationship, Drug; Drug Combinations; Fibroblasts; Free Radical Scavengers; Gingiva; Humans; Metals; Nickel; Oxidative Stress; Periodontal Ligament; Phenols; Phloretin; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; Stilbenes; Time Factors; Zinc | 2013 |
Modulation of NF-κB activation by resveratrol in LPS treated human intestinal cells results in downregulation of PGE2 production and COX-2 expression.
Topics: Antioxidants; Caco-2 Cells; Cell Line; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enterocytes; Gene Expression Regulation, Enzymologic; Humans; Lipopolysaccharides; NF-kappa B; Resveratrol; Stilbenes | 2012 |
The critical role of amino acid residue at position 117 of mouse UDP-glucuronosyltransfererase 1a6a and 1a6b in resveratrol glucuronidation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Biocatalysis; Glucuronides; Glucuronosyltransferase; Isoenzymes; Kinetics; Mice; Molecular Sequence Data; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology; Stilbenes | 2012 |
Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models.
Topics: Adenoviridae; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Dietary Supplements; Equol; Humans; Male; Mice; Mice, Nude; Mutation; Neoplasm Transplantation; Oncolytic Viruses; Phytoestrogens; Prostatic Neoplasms; Resveratrol; Stilbenes; Transplantation, Heterologous | 2012 |
The nuclear factor κB inhibitor (E)-2-fluoro-4'-methoxystilbene inhibits firefly luciferase.
Topics: Animals; Cell Line, Tumor; Copepoda; Fireflies; Inhibitory Concentration 50; Luciferases; Luciferases, Firefly; Luciferases, Renilla; Luminescent Agents; Mice; NF-kappa B; Renilla; Resveratrol; Stilbenes | 2012 |
Ameliorative effects of resveratrol on liver injury in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Lipid Peroxidation; Lipids; Liver; Liver Diseases; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin | 2012 |
Resveratrol protects against acute chemotherapy toxicity induced by doxorubucin in rat erythrocyte and plasma.
Topics: Alanine Transaminase; Animals; Antibiotics, Antineoplastic; Antioxidants; Aspartate Aminotransferases; Calcium; Catalase; Doxorubicin; Erythrocytes; Female; Hydrogen Peroxide; Iron; Lipid Peroxidation; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2012 |
[Simultaneous determination of five active components in resina draconis and its extract by HPLC].
Topics: Chalcones; Chromatography, High Pressure Liquid; Dracaena; Flavones; Resins, Plant; Resveratrol; Stilbenes | 2012 |
Resveratrol decreases inflammation and increases utrophin gene expression in the mdx mouse model of Duchenne muscular dystrophy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Dietary Supplements; Disease Models, Animal; Inflammation Mediators; Leukocytes; Macrophages; Male; Mice; Mice, Inbred mdx; Muscle Development; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Trans-Activators; Transcription Factors; Up-Regulation; Utrophin | 2013 |
Resveratrol protects neurons from cannulae implantation injury: implications for deep brain stimulation.
Topics: Animals; Antioxidants; Behavior, Animal; Catheterization; Deep Brain Stimulation; Dimethyl Sulfoxide; Electrodes, Implanted; Fluoresceins; Fluorescent Dyes; Gene Expression; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Microinjections; Neurons; Neuroprotective Agents; Organic Chemicals; Polymerase Chain Reaction; Postural Balance; Rats; Rats, Long-Evans; Resveratrol; Stilbenes; Subthalamic Nucleus | 2012 |
Resveratrol exerts differential effects in vitro and in vivo against ovarian cancer cells.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Lung Neoplasms; Ovarian Neoplasms; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2012 |
3-[2-(3,5-Dimethoxyphenyl)vinyl]furan protects hippocampal neurons against ischemic damage.
Topics: Animals; Brain Ischemia; Cell Death; Disease Models, Animal; Furans; Hippocampus; Neurons; Neuroprotective Agents; Organ Culture Techniques; Rats; Resveratrol; Stilbenes | 2012 |
Infrared spectroscopy of copper-resveratrol complexes: a joint experimental and theoretical study.
Topics: Copper; Models, Molecular; Molecular Conformation; Quantum Theory; Resveratrol; Spectrophotometry, Infrared; Stilbenes | 2012 |
Resveratrol lacks antifungal activity against Candida albicans.
Topics: Antifungal Agents; Candida albicans; Resveratrol; Stilbenes | 2012 |
In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide.
Topics: Animals; Area Under Curve; Biotransformation; Glucuronides; Half-Life; Injections, Intra-Arterial; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Models, Biological; Resveratrol; Stilbenes; Sulfates | 2012 |
Development of a rapid LC-UV method for the investigation of chemical and metabolic stability of resveratrol oligomers.
Topics: Benzofurans; Chromatography, Liquid; Drug Stability; Glucuronides; Humans; Microsomes, Liver; Molecular Structure; Phenols; Polyphenols; Resveratrol; Stilbenes | 2012 |
[The protection effects of resveratrol on irradiated human pneumonic cell lines and its mechanism].
Topics: Apoptosis; Bronchi; Cell Line; Epithelial Cells; Fetus; Fibroblasts; Humans; Lung; Oxidative Stress; Radiation-Protective Agents; Resveratrol; Stilbenes | 2012 |
A new herb-drug interaction of Polygonum cuspidatum, a resveratrol-rich nutraceutical, with carbamazepine in rats.
Topics: Administration, Oral; Animals; Anticonvulsants; Area Under Curve; Brain; Carbamazepine; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Fallopia japonica; Herb-Drug Interactions; Kidney; Liver; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tissue Distribution | 2012 |
Longitudinal in vivo SPECT/CT imaging reveals morphological changes and cardiopulmonary apoptosis in a rodent model of pulmonary arterial hypertension.
Topics: Animals; Annexins; Apoptosis; Blood Pressure; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Heart Ventricles; Humans; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Systole; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; Ventricular Remodeling | 2012 |
Resveratrol prevents CA1 neurons against ischemic injury by parallel modulation of both GSK-3β and CREB through PI3-K/Akt pathways.
Topics: Animals; Apoptosis; Brain Ischemia; CA1 Region, Hippocampal; Chromones; Cyclic AMP Response Element-Binding Protein; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Red wine and equivalent oral pharmacological doses of resveratrol delay vascular aging but do not extend life span in rats.
Topics: Aging; Animals; Aorta; Blood Vessels; Endothelium-Dependent Relaxing Factors; Exercise Test; Longevity; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Telomere; Tumor Suppressor Protein p53; Wine | 2012 |
Resveratrol promotes cellular glucose utilization in primary cultured cortical neurons via calcium-dependent signaling pathway.
Topics: Animals; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Glucose; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
The vasorelaxing effect of resveratrol on abdominal aorta from rats and its underlying mechanisms.
Topics: Animals; Aorta, Abdominal; Calcium; Endothelium, Vascular; Glyburide; Male; NG-Nitroarginine Methyl Ester; Potassium Channels; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tetraethylammonium; Vasoconstriction; Vasodilation; Vasodilator Agents | 2013 |
Hypopigmentary effects of 4-n-butylresorcinol and resveratrol in combination.
Topics: Animals; Blotting, Western; Cell Line; Cell Survival; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Melanins; Melanocytes; Mice; Microscopy, Phase-Contrast; Monophenol Monooxygenase; Resorcinols; Resveratrol; Skin; Skin Pigmentation; Stilbenes | 2012 |
Enzymatic synthesis of piceid glucosides using maltosyltransferase from Caldicellulosiruptor bescii DSM 6725.
Topics: alpha-Glucosidases; Bacteria; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Escherichia coli; Glucosides; Glucosyltransferases; Magnetic Resonance Spectroscopy; Molecular Structure; Recombinant Proteins; Resveratrol; Solubility; Stilbenes | 2012 |
Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid.
Topics: Amyloid beta-Peptides; Animals; Benzene Derivatives; Benzothiazoles; Cells, Cultured; Coumaric Acids; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Molecular Structure; Molecular Weight; Peptide Fragments; Resveratrol; Stilbenes; Thiazoles | 2012 |
The antioxidant effect of imine resveratrol analogues.
Topics: Antioxidants; Biphenyl Compounds; Electron Spin Resonance Spectroscopy; Imines; Picrates; Resveratrol; Singlet Oxygen; Stilbenes; Structure-Activity Relationship | 2012 |
Resveratrol-mediated apoptosis of hodgkin lymphoma cells involves SIRT1 inhibition and FOXO3a hyperacetylation.
Topics: Acetylation; Apoptosis; B-Lymphocytes; bcl-2-Associated X Protein; Caspase 3; Cell Growth Processes; Cell Line, Tumor; Dose-Response Relationship, Drug; Forkhead Box Protein O3; Forkhead Transcription Factors; Germinal Center; Hodgkin Disease; Humans; Lymph Nodes; Resveratrol; S Phase; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2013 |
[Comparative evaluation of the osteoprotective effects of resveratrol and resveratrol/enalapril combination in the treatment of experimental osteoporosis].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bone and Bones; Drug Therapy, Combination; Enalapril; Endothelium; Female; Microcirculation; Osteoporosis; Ovariectomy; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents | 2012 |
Polyphenols and their components in experimental allergic asthma.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Bronchoconstrictor Agents; Guinea Pigs; Histamine; Interleukin-4; Interleukin-5; Lung; Muscle, Smooth; Ovalbumin; Plethysmography, Whole Body; Polyphenols; Quercetin; Respiratory System; Resveratrol; Stilbenes; Trachea | 2013 |
Ameliorative effects of resveratrol on acute ovarian toxicity induced by total body irradiation in young adult rats.
Topics: Animals; Antioxidants; Catalase; Female; Glutathione Peroxidase; Malondialdehyde; Ovarian Follicle; Ovary; Radiation Injuries; Rats; Rats, Wistar; Resveratrol; Statistics, Nonparametric; Stilbenes | 2012 |
Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cyclooxygenase 2; Down-Regulation; Female; Inflammation; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2012 |
Evaluation of flavonoid and resveratrol chemical libraries reveals abyssinone II as a promising antibacterial lead.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Bacteria; Bacterial Infections; Flavonoids; Humans; Mycobacterium tuberculosis; Resveratrol; Small Molecule Libraries; Stilbenes | 2012 |
Resveratrol inhibits inflammation induced by heat-killed Listeria monocytogenes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line, Transformed; Chemokine CCL2; Cyclooxygenase 2; Dietary Supplements; Enzyme Inhibitors; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hot Temperature; Listeria monocytogenes; Macrophages; MAP Kinase Signaling System; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Nitric Oxide Synthase Type II; Prostaglandins; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
[Regulation trend of resveratrol on TNFα-,IL-1β, IL-6 expressions in bronchoalveolar lavage fluid of RSV-infected BALB/c mice].
Topics: Animals; Bronchoalveolar Lavage Fluid; Female; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred BALB C; Respiratory Syncytial Virus Infections; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ.
Topics: 3T3 Cells; Acetylation; Adipose Tissue, Brown; Adipose Tissue, White; Adult; Amino Acid Sequence; Animals; Cells, Cultured; Energy Metabolism; Female; Humans; Insulin Resistance; Ligands; Lysine; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Obesity; PPAR gamma; Resveratrol; Sequence Alignment; Sirtuin 1; Stilbenes; Thermogenesis; Thiazolidinediones | 2012 |
Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Recombinant Proteins; Resveratrol; Stilbenes; Structure-Activity Relationship | 2012 |
Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood Urea Nitrogen; Carrier Proteins; Creatinine; Disaccharides; Gene Expression Regulation; Glucose Transport Proteins, Facilitative; Glucosides; Gout Suppressants; Hyperuricemia; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Cation Transport Proteins; Organic Cation Transporter 2; Oxonic Acid; Resveratrol; Solute Carrier Family 22 Member 5; Stilbenes; Symporters; Uric Acid | 2012 |
Quercetin, resveratrol, and curcumin are indirect activators of the aryl hydrocarbon receptor (AHR).
Topics: Carbazoles; Cell Line; Chromatography, High Pressure Liquid; Curcumin; Cytochrome P-450 CYP1A1; Hep G2 Cells; Humans; Keratinocytes; Quercetin; Receptors, Aryl Hydrocarbon; Recombinant Proteins; Resveratrol; Stilbenes | 2012 |
Resveratrol preserves myocardial function and perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome.
Topics: Animals; Antioxidants; Biomarkers; Blotting, Western; Coronary Vessels; Diet, High-Fat; Disease Models, Animal; Fluorescent Antibody Technique; Heart; Magnetic Resonance Imaging; Metabolic Syndrome; Myocardial Ischemia; Myocardium; Oxidative Stress; Resveratrol; Stilbenes; Swine; Ventricular Function, Left | 2012 |
The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction.
Topics: Animals; Antioxidants; Bees; Caloric Restriction; Eating; Female; Learning; Longevity; Male; Resveratrol; Stilbenes; Taste Perception | 2012 |
A new resveratrol trimer derivative from Gnetum brunonianum.
Topics: Drugs, Chinese Herbal; Gnetum; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits postoperative adhesion formation in a rat uterine horn adhesion model.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Postoperative Complications; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tissue Adhesions; Uterine Diseases; Uterus | 2012 |
Resveratrol promotes neurotrophic factor release from astroglia.
Topics: Animals; Astrocytes; Blotting, Western; Cells, Cultured; Culture Media; Female; Nerve Growth Factors; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Time Factors | 2012 |
[Chemical constituents from the fruits of Areca catechu].
Topics: Areca; Chromatography; Coumaric Acids; Macrolides; Molecular Structure; Plant Extracts; Quercetin; Resveratrol; Seeds; Stilbenes | 2012 |
[Effects of resveratrol on apoptosis and ROS production in Hepa 1-6 hepatocarcinoma cells].
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Liver Neoplasms; Mice; Plants, Medicinal; Reactive Oxygen Species; Resveratrol; Stilbenes | 2012 |
Glycosylation of trans-resveratrol by plant-cultured cells.
Topics: Biotransformation; Catharanthus; Cells, Cultured; Glucose; Glucosides; Glycosides; Glycosylation; Ipomoea batatas; Molecular Structure; Plant Cells; Resveratrol; Stereoisomerism; Stilbenes; Strophanthus | 2012 |
Acute resveratrol treatment modulates multiple signaling pathways in the ischemic brain.
Topics: Animals; Base Sequence; Blotting, Western; Brain Ischemia; Cyclic AMP Response Element-Binding Protein; DNA Primers; Fluorescent Antibody Technique; Male; Mice; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Protein Kinases; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Trans-Activators; Transcription Factors | 2012 |
Nanophotonic ionization for ultratrace and single-cell analysis by mass spectrometry.
Topics: Metabolome; Microarray Analysis; Nanotechnology; Photons; Resveratrol; Saccharomyces cerevisiae; Single-Cell Analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Wine | 2012 |
The growth of the canine glioblastoma cell line D-GBM and the canine histiocytic sarcoma cell line DH82 is inhibited by the resveratrol oligomers hopeaphenol and r2-viniferin.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dogs; Glioblastoma; Histiocytic Sarcoma; Molecular Structure; Phenols; Polyphenols; Resveratrol; Stilbenes | 2014 |
Production of resveratrol from tyrosine in metabolically engineered Saccharomyces cerevisiae.
Topics: Acyltransferases; Arabidopsis; Arachis; Biotechnology; Coenzyme A Ligases; Coumaric Acids; Genetic Engineering; Phenylalanine Ammonia-Lyase; Propionates; Recombinant Proteins; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Tyrosine | 2012 |
Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway.
Topics: Animals; Anti-HIV Agents; Brain-Derived Neurotrophic Factor; Catechin; Embryo, Mammalian; Gene Expression Regulation; High-Throughput Screening Assays; Hippocampus; HIV Envelope Protein gp120; Humans; Mitochondria; Neurons; Neuroprotective Agents; Nitro Compounds; Oxidative Stress; Primary Cell Culture; Propionates; Protein Precursors; Rats; Resveratrol; Signal Transduction; Stereoisomerism; Stilbenes; tat Gene Products, Human Immunodeficiency Virus | 2012 |
Halloysite clay nanotubes for resveratrol delivery to cancer cells.
Topics: Aluminum Silicates; Antioxidants; Breast Neoplasms; Clay; Humans; Kinetics; MCF-7 Cells; Microscopy, Electron, Transmission; Nanotubes; Resveratrol; Stilbenes | 2012 |
Chemoprevention of benzo(a)pyrene-induced colon polyps in ApcMin mice by resveratrol.
Topics: Adenocarcinoma; Animals; Apoptosis; Benzo(a)pyrene; Cell Cycle; Colonic Neoplasms; Colonic Polyps; Male; Mice; Resveratrol; Stilbenes | 2013 |
Plant polyphenols in prevention of heart disease.
Topics: 4-Butyrolactone; Anti-Inflammatory Agents; Antioxidants; Cardiovascular Diseases; Curcumin; Diet, Mediterranean; Humans; Lignans; Plants; Polyphenols; Resveratrol; Stilbenes | 2012 |
Interaction of resveratrol with membrane glycerophospholipids in model system in vitro.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Calorimetry, Differential Scanning; Glycerophospholipids; Liposomes; Membrane Lipids; Phosphatidylcholines; Phosphatidylserines; Resveratrol; Stilbenes; Transition Temperature | 2012 |
Acute exposure to resveratrol inhibits AMPK activity in human skeletal muscle cells.
Topics: AMP-Activated Protein Kinases; Cell Differentiation; Diabetes Mellitus, Type 2; Drug Interactions; Enzyme Inhibitors; Glucose; Glycogen; Humans; Insulin Resistance; Male; Middle Aged; Muscle Fibers, Skeletal; Palmitates; Phosphorylation; Primary Cell Culture; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Stable free radical scavenging and antiperoxidative properties of resveratrol compared in vitro with some other bioflavonoids.
Topics: Animals; Biphenyl Compounds; Flavonoids; Free Radical Scavengers; Kinetics; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Picrates; Resveratrol; Stilbenes | 2003 |
Cissus quadrangularis ethanol extract upregulates superoxide dismutase, glutathione peroxidase and endothelial nitric oxide synthase expression in hydrogen peroxide-injured human ECV304 cells.
Topics: Antioxidants; Cell Line; Cell Survival; Cissus; Comet Assay; Cytosol; Ethanol; Glutathione Peroxidase; Hemorrhoids; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Medicine, Traditional; Mitochondria; Nitric Oxide Synthase Type III; Plant Components, Aerial; Plant Extracts; Quercetin; Reactive Oxygen Species; Resveratrol; Solvents; Stilbenes; Superoxide Dismutase | 2012 |
Resveratrol-induced changes of the human adipocyte secretion profile.
Topics: Adipocytes; Adipokines; Cell Line; Chromatography, Liquid; Electrophoresis, Gel, Two-Dimensional; Humans; Lipolysis; Proteins; Proteome; Reproducibility of Results; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2012 |
Nanocarriers for topical administration of resveratrol: a comparative study.
Topics: Administration, Cutaneous; Animals; Biological Availability; Cell Survival; Ethanol; Humans; Lipid Peroxidation; Liposomes; Malondialdehyde; Particle Size; Reactive Oxygen Species; Resveratrol; Skin Absorption; Stilbenes; Surface Properties; Surface-Active Agents; Swine | 2013 |
Transcriptomic and metabonomic profiling reveal synergistic effects of quercetin and resveratrol supplementation in high fat diet fed mice.
Topics: Animals; Blood Glucose; Carbohydrate Metabolism; Cluster Analysis; Diet, High-Fat; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Gene Expression Profiling; Lipid Metabolism; Lipids; Liver; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Molecular Sequence Annotation; Oligonucleotide Array Sequence Analysis; Quercetin; Resveratrol; Stilbenes; Transcriptome | 2012 |
Resveratrol upregulates Nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells.
Topics: Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heme Oxygenase-1; Hep G2 Cells; Humans; Hyperglycemia; Insulin Resistance; NF-E2-Related Factor 2; Pyruvaldehyde; Resveratrol; Stilbenes; Up-Regulation | 2012 |
Resveratrol effects on astrocyte function: relevance to neurodegenerative diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; C-Reactive Protein; Cells, Cultured; Chemokine CCL2; Cytokines; Interleukin-12 Subunit p40; Interleukin-23; Lipopolysaccharides; Mice; Neurodegenerative Diseases; Nitric Oxide; Resveratrol; Stilbenes | 2012 |
Evaluation of the effects of resveratrol and bevacizumab on experimental corneal alkali burn.
Topics: Alkalies; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Bevacizumab; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Male; Rabbits; Resveratrol; Stilbenes | 2013 |
Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway.
Topics: Acetylation; Apoptosis; Caspase 8; Cell Line, Tumor; DNA Damage; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Indoles; Leukemia, Myeloid, Acute; Metalloporphyrins; Mitochondria; NF-kappa B; Panobinostat; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Resveratrol; S Phase; Sirtuin 1; Stilbenes; Transcription Factor RelA; U937 Cells; Up-Regulation; Vorinostat | 2012 |
TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol.
Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 6; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Resveratrol; RNA; RNA, Messenger; Signal Transduction; Stilbenes; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Ubiquitination | 2013 |
Resveratrol improves myocardial ischemia and ischemic heart failure in mice by antagonizing the detrimental effects of fractalkine*.
Topics: Animals; Animals, Newborn; Chemokine CX3CL1; Disease Models, Animal; Electrocardiography; Heart Failure; Male; Mice; Mice, Inbred C57BL; Myocardial Ischemia; Platelet Aggregation Inhibitors; Random Allocation; Rats; Resveratrol; Stilbenes; Ventricular Remodeling | 2012 |
Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.
Topics: Animals; Anthracenes; Butadienes; Diabetes Mellitus, Type 2; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Leptin; Resveratrol; Signal Transduction; Stilbenes; Superoxides | 2012 |
Chronic resveratrol treatment ameliorates cell adhesion and mitigates the inflammatory phenotype in senescent human fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Adhesion; Cell Division; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cytokines; Fibroblasts; Gene Expression; Humans; Inflammation; Resveratrol; Stilbenes | 2013 |
An inhibitory effect of resveratrol in the mitotic clonal expansion and insulin signaling pathway in the early phase of adipogenesis.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Cell Cycle; Cyclin A; Cyclin-Dependent Kinase 2; Insulin; Mice; Mitosis; Phytotherapy; Plant Extracts; Receptor, Insulin; Resveratrol; Signal Transduction; Stilbenes | 2012 |
The β-catenin/TCF complex as a novel target of resveratrol in the Wnt/β-catenin signaling pathway.
Topics: Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cell Line; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Colonic Neoplasms; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Protein Binding; Resveratrol; Signal Transduction; Stilbenes; TCF Transcription Factors; Transcription Factor 4; Transcription Factors; Transcription, Genetic; Wnt Proteins | 2012 |
Resveratrol modulates interleukin-1β-induced phosphatidylinositol 3-kinase and nuclear factor κB signaling pathways in human tenocytes.
Topics: Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Interleukin-1beta; Male; Microscopy, Electron; Middle Aged; Mitochondria; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrimidines; Resveratrol; Signal Transduction; Sirtuin 1; src-Family Kinases; Stilbenes; Tendons; Time Factors; Wortmannin | 2012 |
Using liposomes as carriers for polyphenolic compounds: the case of trans-resveratrol.
Topics: Animals; Cell Line; Drug Delivery Systems; Electron Spin Resonance Spectroscopy; Humans; Liposomes; Magnetic Resonance Spectroscopy; Mice; Models, Theoretical; NIH 3T3 Cells; Polyphenols; Resveratrol; Stilbenes | 2012 |
Vodka and wine consumption in a swine model of metabolic syndrome alters insulin signaling pathways in the liver and skeletal muscle.
Topics: Alcohol Drinking; Alcoholic Beverages; Animals; Blood Glucose; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Glucose Transporter Type 4; Immunohistochemistry; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Liver Function Tests; Male; Metabolic Syndrome; Muscle, Skeletal; PPAR alpha; Resveratrol; Stilbenes; Swine; Up-Regulation | 2012 |
Resveratrol prevents hepatic steatosis induced by hepatitis C virus core protein.
Topics: Adenoviridae; Animals; Blotting, Western; Cells, Cultured; Fatty Liver; Gastrointestinal Agents; Gene Expression Profiling; Genetic Vectors; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; Liver; Mice; Mice, Inbred C57BL; PPAR alpha; Recombinant Proteins; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes; Triglycerides; Viral Core Proteins | 2012 |
Combined treatment with capsaicin and resveratrol enhances neuroprotection against glutamate-induced toxicity in mouse cerebral cortical neurons.
Topics: Animals; Antioxidants; Apoptosis; bcl-X Protein; Capsaicin; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytoplasm; Drug Therapy, Combination; Female; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Peroxidase; Interleukin-1beta; Male; Mice; Mice, Inbred ICR; Neurons; Neuroprotective Agents; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; TRPV Cation Channels; Tumor Necrosis Factor-alpha | 2012 |
A plant cell-based system that predicts aβ42 misfolding: potential as a drug discovery tool for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Catechin; Cell Engineering; Curcumin; Drug Evaluation, Preclinical; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Humans; Microscopy, Fluorescence; Models, Biological; Mutation; Nicotiana; Peptide Fragments; Phosphotransferases (Alcohol Group Acceptor); Plant Cells; Protein Binding; Protein Conformation; Protein Folding; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2012 |
Delipidating effect of resveratrol metabolites in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Fatty Acid Synthases; Gene Expression Regulation; Glucuronides; Lipoprotein Lipase; Mice; PPAR gamma; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Triglycerides | 2012 |
Dietary intake of resveratrol enhances the adaptive immunity of aged rats.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Aging; Animals; Hemocyanins; Immunity, Cellular; Immunoglobulin G; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Microbial metabolism. Part 14. Isolation and bioactivity evaluation of microbial metabolites of resveratrol.
Topics: Beauveria; Glucosides; Magnetic Resonance Spectroscopy; Molecular Structure; Penicillium chrysogenum; Resveratrol; Stilbenes | 2013 |
Effect of resveratrol on oxygen consumption by Philasterides dicentrarchi, a scuticociliate parasite of turbot.
Topics: Animals; Antiparasitic Agents; Calcium; Electron Transport; Flatfishes; Membrane Potential, Mitochondrial; Mitochondria; Oligohymenophorea; Oxidative Stress; Oxygen Consumption; Parasitic Sensitivity Tests; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits LPS-induced MAPKs activation via activation of the phosphatidylinositol 3-kinase pathway in murine RAW 264.7 macrophage cells.
Topics: Androstadienes; Animals; Cell Line; Cell Survival; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dinoprostone; Enzyme Activation; Gene Expression Regulation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Wortmannin | 2012 |
Synthesis and antioxidant activity of hydroxylated phenanthrenes as cis-restricted resveratrol analogues.
Topics: Antioxidants; Hydroxylation; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Resveratrol; Stereoisomerism; Stilbenes | 2012 |
Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols.
Topics: Molecular Structure; Picea; Plant Bark; Plant Extracts; Polyphenols; Resveratrol; Stilbenes | 2012 |
Hypohalous acid-mediated halogenation of resveratrol and its role in antioxidant and antimicrobial activities.
Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bromates; Cell Line; Fungi; Halogenation; Hemolysis; Humans; Hypochlorous Acid; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2012 |
Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response.
Topics: beta-Defensins; Cell Line; Cytoprotection; Enzyme-Linked Immunosorbent Assay; Gene Expression; Glucosides; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Inflammation; Interleukin-6; Interleukin-8; Keratinocytes; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Moderate red wine and grape juice consumption modulates the hydrolysis of the adenine nucleotides and decreases platelet aggregation in streptozotocin-induced diabetic rats.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Deaminase; Animals; Antioxidants; Beverages; Blood Platelets; Caffeic Acids; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hydrolysis; Male; Plant Preparations; Platelet Aggregation; Pyrophosphatases; Quercetin; Rats; Rats, Wistar; Resveratrol; Rutin; Stilbenes; Vitis; Wine | 2013 |
Pterostilbene-induced tumor cytotoxicity: a lysosomal membrane permeabilization-dependent mechanism.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Caspases; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; HSP70 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; L-Lactate Dehydrogenase; Lysosomes; Microscopy, Confocal; Necrosis; Neoplasms; Permeability; Phagosomes; Resveratrol; Stilbenes | 2012 |
Resveratrol attenuates oxidative stress and prevents steatosis and hypertension in obese rats programmed by early weaning.
Topics: Animals; Antioxidants; Blood Glucose; Dyslipidemias; Fatty Liver; Female; Glutathione Peroxidase; Hyperphagia; Hypertension; Insulin Resistance; Liver; Obesity; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Weaning | 2013 |
Effects of resveratrol on growth and function of rat ovarian granulosa cells.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Granulosa Cells; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2012 |
Effects of resveratrol on longevity, cognitive ability and aging-related histological markers in the annual fish Nothobranchius guentheri.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Galactosidase; Body Size; Cognition; Drug Evaluation, Preclinical; Female; Fishes; Lipofuscin; Longevity; Male; Maze Learning; Models, Animal; Motor Activity; Neurodegenerative Diseases; Neuroprotective Agents; Resveratrol; Stilbenes | 2012 |
Dietary resveratrol prevents the development of food allergy in mice.
Topics: Animals; Antigens, CD; Antioxidants; Cholera Toxin; Cyclic AMP; Dendritic Cells; Female; Food Hypersensitivity; GATA3 Transcription Factor; Gene Expression; Immunoglobulin E; Interferon-alpha; Interleukin-13; Interleukin-4; Lymph Nodes; Mice; Ovalbumin; Resveratrol; Signal Transduction; Spleen; Stilbenes; T-Box Domain Proteins; T-Lymphocytes | 2012 |
Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction.
Topics: Animals; Carbazoles; Cell Line; Forkhead Transcription Factors; Gene Expression Regulation; Glucose; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lectins, C-Type; Membrane Glycoproteins; Nerve Tissue Proteins; Palmitates; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Trans-Activators | 2012 |
Side-effects of resveratrol in HepG2 cells: reduced pten and increased bcl-xl mRNA expression.
Topics: Antineoplastic Agents, Phytogenic; bcl-X Protein; Cell Proliferation; Hep G2 Cells; Humans; PTEN Phosphohydrolase; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
Targeted acetylation of NF-kappaB/RelA and histones by epigenetic drugs reduces post-ischemic brain injury in mice with an extended therapeutic window.
Topics: Acetylation; Animals; Benzamides; Brain; Brain Ischemia; Cell Hypoxia; Disease Models, Animal; Epigenesis, Genetic; Glucose; Histone Deacetylase Inhibitors; Histones; Infarction, Middle Cerebral Artery; Male; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; NF-kappa B; Pyridines; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factor RelA | 2013 |
Resveratrol initiates differentiation of mouse skeletal muscle-derived C2C12 myoblasts.
Topics: Animals; Cell Differentiation; Cell Line; Cell Proliferation; Cell Shape; Mice; MicroRNAs; Muscle Fibers, Skeletal; Myoblasts, Skeletal; Myosins; Resveratrol; Stilbenes; Transcription Factors; Transcription, Genetic | 2012 |
Resveratrol inhibits proliferation of primary rat hepatocytes in G0/G1 by inhibiting DNA synthesis.
Topics: Animals; Antioxidants; Cell Division; Cell Line, Transformed; Cell Proliferation; Cells, Cultured; DNA; G1 Phase; G2 Phase; Hepatocytes; Humans; Rats; Resting Phase, Cell Cycle; Resveratrol; Stilbenes | 2012 |
[Effects of resveratrol on the morphology of lipid droplets and the expression of lipid droplet-associated proteins in mouse primary hepatocytes].
Topics: Animals; Carrier Proteins; Cells, Cultured; Dose-Response Relationship, Drug; Fatty Liver; Hepatocytes; Lipid Metabolism; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Perilipin-1; Perilipin-2; Phosphoproteins; Resveratrol; Stilbenes; Triglycerides | 2012 |
Stilbene levels and antioxidant activity of Vranec and Merlot wines from Macedonia: effect of variety and enological practices.
Topics: Antioxidants; Industrial Microbiology; Resveratrol; Stilbenes; Vitis; Wine; Yeasts | 2012 |
The binding of resveratrol to monomer and fibril amyloid beta.
Topics: Amyloid beta-Peptides; Humans; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Protein Binding; Resveratrol; Stilbenes; Surface Plasmon Resonance | 2012 |
Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects.
Topics: Adult; Antioxidants; Comet Assay; Dietary Supplements; Female; Genomic Instability; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes; Young Adult | 2012 |
Resveratrol attenuates oxidative damage and ameliorates cognitive impairment in the brain of senescence-accelerated mice.
Topics: Aging; Animals; Antioxidants; Brain; Cognition Disorders; DNA, Mitochondrial; Fallopia japonica; Gene Deletion; Glutathione Peroxidase; Male; Malondialdehyde; Maze Learning; Memory; Mice; Oxidative Stress; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase | 2012 |
Resveratrol inhibits Epstein Barr Virus lytic cycle in Burkitt's lymphoma cells by affecting multiple molecular targets.
Topics: Antiviral Agents; Cell Line, Tumor; Herpesvirus 4, Human; Humans; Protein Biosynthesis; Resveratrol; Signal Transduction; Stilbenes; Viral Proteins; Virus Replication | 2012 |
Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A).
Topics: Animals; Anti-Asthmatic Agents; Asthma; Calpain; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2012 |
Influence of stearic acids on resveratrol-HSA interaction.
Topics: Amino Acid Sequence; Humans; Molecular Sequence Data; Protein Binding; Protein Interaction Domains and Motifs; Resveratrol; Serum Albumin; Stearic Acids; Stilbenes | 2012 |
SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.
Topics: Adult; Aged; Apoptosis; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Intervertebral Disc Degeneration; Lumbar Vertebrae; Male; Middle Aged; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Resveratrol; Ribonucleotide Reductases; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Young Adult | 2013 |
Effects of resveratrol on blood homocysteine level, on homocysteine induced oxidative stress, apoptosis and cognitive dysfunctions in rats.
Topics: Animals; Antioxidants; Aorta; Apoptosis; Cognition Disorders; DNA Fragmentation; Homocysteine; In Situ Nick-End Labeling; Lipid Peroxidation; Male; Maze Learning; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2012 |
Resveratrol upregulated heat shock proteins and extended the survival of G93A-SOD1 mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Disease Models, Animal; DNA-Binding Proteins; Glial Fibrillary Acidic Protein; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Chaperones; Motor Neurons; Neoplasm Proteins; Resveratrol; Spinal Cord; Stilbenes; Superoxide Dismutase; Survival Analysis; Transcription Factors; Up-Regulation | 2012 |
Protective effects of resveratrol on cisplatin-dependent inner-ear damage in rats.
Topics: Animals; Antineoplastic Agents; Cisplatin; Hearing Loss; Male; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Anti-HIV-1 activity of resveratrol derivatives and synergistic inhibition of HIV-1 by the combination of resveratrol and decitabine.
Topics: Anti-HIV Agents; Azacitidine; Decitabine; Dose-Response Relationship, Drug; Drug Synergism; HIV-1; Humans; Molecular Structure; Resveratrol; Stilbenes | 2012 |
Anti-Acanthamoebic properties of resveratrol and demethoxycurcumin.
Topics: Acanthamoeba castellanii; Brain; Cell Adhesion; Cell Death; Cells, Cultured; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Microvessels; Peptide Hydrolases; Resveratrol; Stilbenes | 2012 |
Pre-bottling use of dehydrated waste grape skins to improve colour, phenolic and aroma composition of red wines.
Topics: Biotechnology; Catechin; Color; Fruit; Gas Chromatography-Mass Spectrometry; Humans; Phenols; Resveratrol; Stilbenes; Vitis; Volatile Organic Compounds; Wine | 2013 |
Stimulation of cytosolic and mitochondrial calcium mobilization by indomethacin in Caco-2 cells: modulation by the polyphenols quercetin, resveratrol and rutin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Caco-2 Cells; Calcium; Caspases; Cytochromes c; Cytosol; Endoplasmic Reticulum; Humans; Indomethacin; Inositol 1,4,5-Trisphosphate Receptors; Mitochondria; Quercetin; Resveratrol; Rutin; Ryanodine Receptor Calcium Release Channel; Stilbenes | 2012 |
Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins.
Topics: 1-Methyl-4-phenylpyridinium; Antioxidants; Cell Line, Tumor; Chloramines; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Methionine; Methionine Sulfoxide Reductases; Models, Biological; Neuroblastoma; Neurotoxins; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Tosyl Compounds; Up-Regulation | 2013 |
Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide.
Topics: Animals; Antioxidants; Arsenic; Arsenic Trioxide; Arsenicals; Catalase; Glutathione; Glutathione Disulfide; Liver; Male; Oxidative Stress; Oxides; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells.
Topics: Albumins; Aorta; Cell Membrane Permeability; Cell Proliferation; Cells, Cultured; Cellular Senescence; Cyclic AMP; Endothelium, Vascular; Fetal Blood; Guanine Nucleotide Exchange Factors; Humans; In Vitro Techniques; Occludin; Phosphorylation; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tight Junction Proteins | 2012 |
Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Cell Line, Tumor; Diflunisal; Dinitrophenols; Humans; Mutation; Phthalic Acids; Prealbumin; Protein Binding; Resveratrol; Stilbenes | 2012 |
Resveratrol analog 4-[2-(3,5-dimethoxyphenyl)vinyl]pyridine reduces differentiation of the 3T3-L1 adipocyte.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Adipocytes; Animals; Anti-Obesity Agents; Blotting, Western; Cell Differentiation; Dose-Response Relationship, Drug; Fatty Acid Synthases; Gene Expression Regulation, Enzymologic; Inhibitory Concentration 50; Mice; Pyridines; Resveratrol; Stilbenes; Vinyl Compounds | 2013 |
Resveratrol mediates anti-atherogenic effects on cholesterol flux in human macrophages and endothelium via PPARγ and adenosine.
Topics: Adenosine; Animals; Apolipoprotein A-I; Atherosclerosis; Biological Transport; CD36 Antigens; Cell Line; Cholesterol; Endothelium; Foam Cells; Gene Expression Regulation; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Monocytes; PPAR gamma; Receptors, Adenosine A2; Resveratrol; Stilbenes | 2013 |
Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Cell Line, Tumor; Diet; Female; Glucuronides; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes; Sulfates; Tumor Burden; Vincristine; Xenograft Model Antitumor Assays | 2012 |
Differential cell-protective function of two resveratrol (trans-3,5,4'-trihydroxystilbene) glucosides against oxidative stress.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Biphenyl Compounds; Blotting, Western; Cell Death; Cell Line; Cells, Cultured; Chromans; Cytoprotection; Free Radical Scavengers; Free Radicals; Glucosides; Immunohistochemistry; Mice; Myoblasts; Myocytes, Cardiac; Oxidative Stress; Phytolacca americana; Picrates; Polymerase Chain Reaction; Rats; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Neuroprotective effect of resveratrol against prenatal stress induced cognitive impairment and possible involvement of Na(+), K(+)-ATPase activity.
Topics: Animals; Antioxidants; Brain; Cognition Disorders; Disease Models, Animal; Female; Male; Maze Learning; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Restraint, Physical; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes; Stress, Psychological | 2013 |
Inhibitory effects of resveratrol analogs on mushroom tyrosinase activity.
Topics: Agaricales; Enzyme Activation; Enzyme Inhibitors; Monophenol Monooxygenase; Resveratrol; Stilbenes | 2012 |
Resveratrol supplementation influences bone properties in the tibia of hindlimb-suspended mature Fisher 344 × Brown Norway male rats.
Topics: Absorptiometry, Photon; Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Calcium; Dietary Supplements; Hindlimb; Hindlimb Suspension; Male; Osteocalcin; Osteoporosis; Rats; Rats, Inbred BN; Rats, Inbred F344; Resveratrol; Stilbenes; Tibia | 2012 |
Theoretical and experimental exploration of the photochemistry of resveratrol: beyond the simple double bond isomerization.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Electrons; Kinetics; Light; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenanthrenes; Photochemical Processes; Protons; Resveratrol; Stereoisomerism; Stilbenes; Thermodynamics | 2012 |
The synergic effect of regular exercise and resveratrol on kainate-induced oxidative stress and seizure activity in mice.
Topics: Anaerobic Threshold; Animals; Antioxidants; Body Weight; Catalase; Kainic Acid; Lactic Acid; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Physical Conditioning, Animal; Resveratrol; Seizures; Stilbenes; Superoxide Dismutase; Swimming | 2013 |
SIRT1 regulates dendritic development in hippocampal neurons.
Topics: Amyloid beta-Peptides; Animals; Cell Survival; Dendrites; Hippocampus; Immunoblotting; NAD; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
3,4-Dimethoxystilbene, a resveratrol derivative with anti-angiogenic effect, induces both macroautophagy and apoptosis in endothelial cells.
Topics: Adenine; AMP-Activated Protein Kinases; Angiogenesis Inhibitors; Apoptosis; Autophagy; Autophagy-Related Protein 5; bcl-2-Associated X Protein; Calcium; Caspase 3; Caspase 9; Cell Line; Cell Movement; Cell Proliferation; Cell Survival; Cytochromes c; Human Umbilical Vein Endothelial Cells; Humans; Microtubule-Associated Proteins; Neovascularization, Physiologic; Reactive Oxygen Species; Resveratrol; RNA Interference; RNA, Small Interfering; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2013 |
Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer.
Topics: Adenylate Kinase; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Catechin; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gefitinib; Gene Expression Regulation; Humans; Mice; Mice, SCID; Polyphenols; Proto-Oncogene Proteins c-akt; Quercetin; Quinazolines; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Vitis; Xenograft Model Antitumor Assays | 2012 |
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cytokines; Disease Models, Animal; Female; Heterocyclic Compounds, 4 or More Rings; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Respiratory System; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes | 2013 |
Photochemical and photocatalytic degradation of trans-resveratrol.
Topics: Catalysis; Isomerism; Kinetics; Light; Photolysis; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes; Titanium; Ultraviolet Rays | 2013 |
Lentivirus-mediated Sirt1 shRNA and resveratrol independently induce porcine preadipocyte apoptosis by canonical apoptotic pathway.
Topics: Adipocytes; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cells, Cultured; Gene Silencing; Genetic Vectors; Lentivirus; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Swine | 2013 |
Pharmacokinetics and tissue distribution of resveratrol, emodin and their metabolites after intake of Polygonum cuspidatum in rats.
Topics: Animals; Brain; Emodin; Fallopia japonica; Glucuronides; Kidney; Liver; Lung; Male; Myocardium; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Rhizome; Stilbenes; Tissue Distribution | 2012 |
Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins.
Topics: Acetylation; Autophagy; Cell Line, Tumor; Cytoplasm; Enzyme Activation; Gene Expression; Humans; Microscopy, Fluorescence; Polyphenols; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Beneficial effects of lysosome-modulating and other pharmacological and nanocarrier agents on amyloid-beta-treated cells.
Topics: Acetylcarnitine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Drug Carriers; Endosomes; Humans; Kaempferols; Lactic Acid; Lysosomes; Memantine; Mifepristone; Nanoparticles; Neuroprotective Agents; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; Stilbenes | 2012 |
Ultrasonic-assisted extraction of the botanical dietary supplement resveratrol and other constituents of Polygonum cuspidatum.
Topics: Dietary Supplements; Electron Spin Resonance Spectroscopy; Fallopia japonica; Models, Chemical; Molecular Structure; Plant Roots; Resveratrol; Stereoisomerism; Stilbenes; Taiwan; Ultrasonics | 2012 |
Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1.
Topics: Animals; Dose-Response Relationship, Drug; Down-Regulation; Electroretinography; Heme Oxygenase-1; Intraocular Pressure; Matrix Metalloproteinase 9; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Resveratrol; Retina; Retinal Vessels; RNA, Messenger; Stilbenes; Thy-1 Antigens; Up-Regulation; Vimentin | 2013 |
Density functional theory (B3LYP) study of substituent effects on O-H bond dissociation enthalpies of trans-resveratrol derivatives and the role of intramolecular hydrogen bonds.
Topics: Computer Simulation; Electrons; Free Radicals; Hydrogen Bonding; Models, Molecular; Oxidation-Reduction; Phenols; Resveratrol; Stilbenes; Thermodynamics | 2012 |
A glass of wine: how good is good? The resveratrol lesson*.
Topics: Animals; Chemokine CX3CL1; Heart Failure; Male; Myocardial Ischemia; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes | 2012 |
Natural therapies assessment for the treatment of endometriosis.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Catechin; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endometriosis; Endometrium; Female; Humans; Injections, Intraperitoneal; Intestinal Diseases; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Random Allocation; Resveratrol; Stilbenes | 2013 |
Protection against recurrent stroke with resveratrol: endothelial protection.
Topics: Administration, Oral; Animals; Biomarkers; Blood Gas Analysis; Blood Pressure; Blood-Brain Barrier; Body Temperature; Brain; Cell Death; Cell Hypoxia; Cerebrovascular Circulation; Endothelial Cells; Endothelium, Vascular; Glucose; Heart Rate; Inflammation; Liver; Nitrosation; Oxidation-Reduction; Oxygen; Rats; Recurrence; Resveratrol; Stilbenes; Stress, Physiological; Stroke; Treatment Outcome | 2012 |
Resveratrol up-regulates hepatic uncoupling protein 2 and prevents development of nonalcoholic fatty liver disease in rats fed a high-fat diet.
Topics: Adipose Tissue; Animals; Biomarkers; Blotting, Western; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Fatty Liver; Ion Channels; Liver; Male; Mitochondrial Proteins; Non-alcoholic Fatty Liver Disease; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; RNA, Ribosomal, 18S; Stilbenes; Triglycerides; Uncoupling Protein 2; Up-Regulation | 2012 |
Resveratrol depletes mitochondrial DNA and inhibition of autophagy enhances resveratrol-induced caspase activation.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Cell Proliferation; DNA, Mitochondrial; Humans; Mitochondria; Resveratrol; Stilbenes | 2013 |
Gut and microbial resveratrol metabolite profiling after moderate long-term consumption of red wine versus dealcoholized red wine in humans by an optimized ultra-high-pressure liquid chromatography tandem mass spectrometry method.
Topics: Biological Availability; Chromatography, High Pressure Liquid; Ethanol; Humans; Intestinal Mucosa; Intestines; Middle Aged; Reference Standards; Reproducibility of Results; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Wine | 2012 |
trans-Resveratrol in nutraceuticals: issues in retail quality and effectiveness.
Topics: Antioxidants; Biflavonoids; Catechin; Cell Differentiation; Cell Proliferation; Chromatography, High Pressure Liquid; Commerce; Dietary Supplements; Discriminant Analysis; Erythroid Cells; Flavonoids; Food Labeling; Humans; K562 Cells; Least-Squares Analysis; Polyphenols; Proanthocyanidins; Resveratrol; Stilbenes | 2012 |
Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Activation; Kidney; Lipid Metabolism; Lipotropic Agents; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Oxidative Stress; Protective Agents; Protein Processing, Post-Translational; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
Characterization of nanochannel delivery membrane systems for the sustained release of resveratrol and atorvastatin: new perspectives on promoting heart health.
Topics: Anticholesteremic Agents; Atorvastatin; Cell Line; Cell Survival; Diffusion; Drug Delivery Systems; Drug Implants; Equipment Design; Heptanoic Acids; Humans; Membranes, Artificial; Nanostructures; Pyrroles; Resveratrol; Stilbenes; Vasodilator Agents | 2013 |
Development of novel cationic chitosan-and anionic alginate-coated poly(D,L-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol.
Topics: Cations; Chitosan; Delayed-Action Preparations; Diffusion; Light; Nanocapsules; Particle Size; Polyglactin 910; Radiation-Protective Agents; Resveratrol; Stilbenes | 2012 |
Protective effects of resveratrol on salivary gland damage induced by total body irradiation in rats.
Topics: Angiogenesis Inhibitors; Animals; Antioxidants; Disease Models, Animal; Female; Glutathione; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Salivary Gland Diseases; Salivary Glands; Stilbenes; Treatment Outcome; Whole-Body Irradiation | 2012 |
Radioprotective activity and cytogenetic effect of resveratrol in human lymphocytes: an in vitro evaluation.
Topics: Cell Proliferation; Cells, Cultured; Chromosome Aberrations; Dose-Response Relationship, Drug; Gamma Rays; Humans; Lymphocytes; Mitotic Index; Mutagenicity Tests; Radiation-Protective Agents; Resveratrol; Sister Chromatid Exchange; Stilbenes | 2013 |
Nanoencapsulation of quercetin and resveratrol into elastic liposomes.
Topics: Adipocytes; Chemistry, Physical; Cholesterol; Chromatography, High Pressure Liquid; Cyclodextrins; Deoxycholic Acid; Drug Delivery Systems; Drug Design; Elasticity; Kinetics; Liposomes; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Phosphatidylcholines; Quercetin; Resveratrol; Solubility; Stilbenes; Time Factors | 2013 |
An analogue of resveratrol HS-1793 exhibits anticancer activity against MCF-7 cells via inhibition of mitochondrial biogenesis gene expression.
Topics: Antineoplastic Agents; Caspases; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mitochondrial Proteins; Mitochondrial Turnover; Naphthols; Oxidative Phosphorylation; Resorcinols; Resveratrol; Stilbenes | 2012 |
Resveratrol inhibits the proliferation of neural progenitor cells and hippocampal neurogenesis.
Topics: AMP-Activated Protein Kinases; Animals; Brain-Derived Neurotrophic Factor; Cell Death; Cell Proliferation; Cell Survival; Cyclic AMP Response Element-Binding Protein; Dentate Gyrus; Embryo, Mammalian; Enzyme Activation; Hippocampus; Male; Memory; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Phosphorylation; Resveratrol; Stilbenes | 2012 |
Resveratrol attenuates L-DOPA-induced hydrogen peroxide toxicity in neuronal cells.
Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Drug Interactions; Fibroblasts; Fluoresceins; Humans; Hydrogen Peroxide; Levodopa; Monoamine Oxidase; Nerve Tissue Proteins; Neuroblastoma; Neurons; Neuroprotective Agents; Oxidative Stress; Quercetin; Resveratrol; Stilbenes; Tyrosine; Tyrosine 3-Monooxygenase | 2012 |
The protective effects of resveratrol on human coronary artery endothelial cell damage induced by hydrogen peroxide in vitro.
Topics: Antioxidants; Cells, Cultured; Coronary Vessels; Endothelial Cells; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Humans; Hydrogen Peroxide; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Transcriptional expression of Stilbene synthase genes are regulated developmentally and differentially in response to powdery mildew in Norton and Cabernet Sauvignon grapevine.
Topics: Acyltransferases; Ascomycota; Fruit; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Host-Pathogen Interactions; Plant Diseases; Plant Leaves; Plant Proteins; Real-Time Polymerase Chain Reaction; Resveratrol; Species Specificity; Stilbenes; Vitis | 2012 |
Resveratrols in Vitis berry skins and leaves: their extraction and analysis by HPLC.
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Fruit; Plant Extracts; Plant Leaves; Resveratrol; Stilbenes; Vitis | 2013 |
Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice.
Topics: Animals; Bone Marrow; Carbazoles; Cells, Cultured; Cytoprotection; Male; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Radiation Injuries, Experimental; Radiation-Protective Agents; Resveratrol; Sirtuin 1; Stem Cells; Stilbenes | 2013 |
Induction of trans-resveratrol and extracellular pathogenesis-related proteins in elicited suspension cultured cells of Vitis vinifera cv Monastrell.
Topics: Acetates; Anti-Infective Agents; Cells, Cultured; Cyclodextrins; Cyclopentanes; Disease Resistance; Ethylenes; Gene Expression Regulation, Plant; Genes, Plant; Oxylipins; Plant Diseases; Plant Growth Regulators; Plant Proteins; Resveratrol; Salicylic Acid; Signal Transduction; Stilbenes; Vitis | 2013 |
[Resveratrol stimulates extracellular matrix synthesis in degenerative nucleus pulposus cells via upregulation of SIRT1].
Topics: Aged; Aggrecans; Cells, Cultured; Collagen Type II; Dose-Response Relationship, Drug; Extracellular Matrix; Female; Humans; Intervertebral Disc; Male; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation | 2012 |
EGFR mediates LPA-induced proteolytic enzyme expression and ovarian cancer invasion: inhibition by resveratrol.
Topics: Cell Line, Tumor; ErbB Receptors; Female; Humans; Immunoblotting; Immunoprecipitation; Lysophospholipids; Ovarian Neoplasms; Phosphorylation; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2013 |
Alleviative effects of resveratrol on nonalcoholic fatty liver disease are associated with up regulation of hepatic low density lipoprotein receptor and scavenger receptor class B type I gene expressions in rats.
Topics: Animals; Energy Metabolism; fas Receptor; Fatty Liver; Gene Expression; Lipid Metabolism; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Receptors, LDL; Resveratrol; Scavenger Receptors, Class B; Stilbenes; Thyroid Hormone Receptors beta; Weight Gain | 2013 |
Design, synthesis, and evaluation of resveratrol derivatives as Aß(₁-₄₂) aggregation inhibitors, antioxidants, and neuroprotective agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship | 2012 |
Dietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8.
Topics: Aging; Alzheimer Disease; Animals; Biomarkers; Blotting, Western; Caloric Restriction; Cognition; Dietary Supplements; Disease Models, Animal; Enzyme Inhibitors; Immunohistochemistry; Longevity; Mice; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2013 |
Analysis and functionality of major polyphenolic components of Polygonum cuspidatum (itadori).
Topics: alpha-Glucosidases; Antioxidants; Chlorogenic Acid; Enzyme Inhibitors; Fallopia japonica; Glucosides; Glycoside Hydrolase Inhibitors; Plant Extracts; Plant Leaves; Plant Roots; Plants, Medicinal; Polyphenols; Resveratrol; Stilbenes | 2012 |
Crystallization of amorphous solid dispersions of resveratrol during preparation and storage-Impact of different polymers.
Topics: Acrylates; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Crystallization; Crystallography, X-Ray; Drug Stability; Drug Storage; Hydrogen Bonding; Hypromellose Derivatives; Methylcellulose; Molecular Structure; Polymers; Povidone; Powder Diffraction; Resveratrol; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Stilbenes; Technology, Pharmaceutical; Time Factors | 2013 |
SIRT1 sensitizes hepatocellular carcinoma cells expressing hepatitis B virus X protein to oxidative stress-induced apoptosis.
Topics: Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Humans; Liver Neoplasms; MAP Kinase Kinase 4; Oxidative Stress; Phosphorylation; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Trans-Activators; Up-Regulation; Viral Regulatory and Accessory Proteins | 2012 |
Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription.
Topics: Aged; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arthritis, Rheumatoid; Caspase 3; Caspase 7; Cell Movement; Cell Proliferation; Cells, Cultured; Dexamethasone; Drug Evaluation, Preclinical; Female; Gene Expression Profiling; Humans; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Phenotype; Phytotherapy; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes | 2013 |
Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cell Differentiation; Gene Expression Regulation; Mitochondria; Mitochondrial Proton-Translocating ATPases; Neurites; PC12 Cells; Rats; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2013 |
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).
Topics: Animals; Enzyme Induction; HEK293 Cells; Humans; Macrophages; Mice; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes; Structure-Activity Relationship; Thiazoles | 2012 |
Synthesis of novel azo-resveratrol, azo-oxyresveratrol and their derivatives as potent tyrosinase inhibitors.
Topics: Agaricales; Azo Compounds; Dose-Response Relationship, Drug; Enzyme Inhibitors; Molecular Structure; Monophenol Monooxygenase; Plant Extracts; Resveratrol; Stilbenes; Structure-Activity Relationship | 2012 |
1,2-Dibromotetrachloroethane: an ozone-friendly reagent for the in situ Ramberg-Bäcklund rearrangement and its use in the formal synthesis of E-resveratrol.
Topics: Alkenes; Hydrocarbons, Halogenated; Indicators and Reagents; Molecular Structure; Ozone; Resveratrol; Stereoisomerism; Stilbenes | 2012 |
Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.
Topics: Animals; Antioxidants; Biological Transport; Cell Line; Cholesterol; Feces; Female; Gene Expression; Hydrocarbons, Fluorinated; Liver; Liver X Receptors; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Orphan Nuclear Receptors; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Sulfonamides | 2013 |
Synergistic anti-cancer effects of resveratrol and chemotherapeutic agent clofarabine against human malignant mesothelioma MSTO-211H cells.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cell Line, Tumor; Cell Proliferation; Chromones; Clofarabine; Cyclin D1; Enzyme Inhibitors; Epithelial Cells; Humans; Mesothelioma; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Resveratrol; Sp1 Transcription Factor; Stilbenes | 2013 |
Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Vimentin | 2013 |
WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1.
Topics: Androstadienes; Caspase 3; CCN Intercellular Signaling Proteins; Cell Hypoxia; Cell Survival; Chromones; Enzyme Inhibitors; Forkhead Box Protein O3; Forkhead Transcription Factors; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Homeostasis; Humans; Morpholines; Neurons; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Wortmannin | 2013 |
Transient transfection of a wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; MCF-7 Cells; Resveratrol; Stilbenes; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53 | 2012 |
Protective effects of resveratrol on sepsis-induced DNA damage in the lymphocytes of rats.
Topics: Animals; Antimutagenic Agents; Comet Assay; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Lymphocytes; Rats; Rats, Wistar; Resveratrol; Sepsis; Stilbenes | 2013 |
[Effect of resveratrol on expression of cdk5 in activation effect of LPS on N9 microglia cells].
Topics: Cell Line; Cyclin-Dependent Kinase 5; Humans; Lipopolysaccharides; Microglia; Resveratrol; Stilbenes | 2012 |
Activity-guided isolation of resveratrol oligomers from a grapevine-shoot extract using countercurrent chromatography.
Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Line, Tumor; Chemical Fractionation; Countercurrent Distribution; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phenols; Plant Shoots; Resveratrol; Stilbenes; Vitis | 2012 |
Lack of resveratrol neuroprotection in developing rats treated with kainic acid.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain Waves; Cell Count; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid Agonists; Female; Gene Expression Regulation, Developmental; Hippocampus; Kainic Acid; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Resveratrol; Status Epilepticus; Stilbenes | 2013 |
Cytotoxic effect of natural trans-resveratrol obtained from elicited Vitis vinifera cell cultures on three cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Culture Techniques; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclodextrins; Dose-Response Relationship, Drug; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Time Factors; Up-Regulation; Vitis | 2012 |
Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences.
Topics: Adrenal Glands; Animals; Antidepressive Agents; Body Weight; Brain; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Fluoxetine; Food Preferences; Gene Expression Regulation; Imipramine; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Psychological; Sucrose; Sweetening Agents; Time Factors; Water Deprivation | 2013 |
Involvement of DNA methylation in the regulation of STS10 gene expression in Vitis amurensis.
Topics: Actins; Acyltransferases; DNA Methylation; Gene Expression Regulation, Plant; Glyceraldehyde-3-Phosphate Dehydrogenases; Plant Proteins; Resveratrol; Stilbenes; Vitis | 2013 |
A molecular mechanism for direct sirtuin activation by resveratrol.
Topics: Acetylation; Caloric Restriction; Crystallography, X-Ray; Humans; Peptides; Protein Binding; Protein Conformation; Resveratrol; Sirtuin 1; Sirtuin 3; Sirtuins; Stilbenes; Substrate Specificity | 2012 |
Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves Nrf2 downregulation.
Topics: Adenine Nucleotides; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinonucleosides; Blotting, Western; Cell Proliferation; Clofarabine; Down-Regulation; Drug Synergism; Heme Oxygenase-1; Humans; Mesothelioma; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2012 |
[Inhibitory effect of resveratrol on ischemia reperfusion-induced cardiocyte apoptosis and its relationship with PI3K-Akt signaling pathway].
Topics: Animals; Apoptosis; Down-Regulation; Humans; Male; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.
Topics: Animals; Antioxidants; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Insulin; Insulin-Like Growth Factor Binding Proteins; Male; Mice; Mice, SCID; Proportional Hazards Models; Prostatic Neoplasms; Resveratrol; Stilbenes; Survival Analysis; Xenograft Model Antitumor Assays | 2013 |
Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts.
Topics: Adenoviridae; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Genetic Vectors; Gingiva; Humans; Inflammation Mediators; Interleukins; Lipopolysaccharides; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinases; NF-kappa B; Nicotine; Nicotinic Agonists; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2013 |
Development and validation of a method for the determination of (E)-resveratrol and related phenolic compounds in beverages using molecularly imprinted solid phase extraction.
Topics: Beverages; Chromatography, High Pressure Liquid; Molecular Imprinting; Phenols; Resveratrol; Solid Phase Extraction; Stilbenes; Wine | 2013 |
Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: investigation of the role of gender.
Topics: Animals; Antioxidants; Brain; Cell Respiration; Electron Transport; Energy Metabolism; Female; Hydrogen Peroxide; Lipid Peroxidation; Liver; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Oxidative Stress; Oxygen Consumption; Phosphorylation; Rats; Rats, Wistar; Resveratrol; Sex Factors; Signal Transduction; Stilbenes | 2013 |
Resveratrol inhibited hydroquinone-induced cytotoxicity in mouse primary hepatocytes.
Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Hepatocytes; Hydroquinones; Male; Mice; Mice, Inbred C3H; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Time Factors | 2012 |
Potion or poison? Resveratrol.
Topics: Antioxidants; Cytochrome P-450 CYP3A; Dietary Supplements; Drug Interactions; Evidence-Based Medicine; Humans; Resveratrol; Stilbenes | 2012 |
In vitro antioxidant activities of three red wine polyphenols and their mixtures: an interaction study.
Topics: Antioxidants; Caffeic Acids; Deoxyribose; Ferric Compounds; Oxidation-Reduction; Polyphenols; Quercetin; Resveratrol; Stilbenes; Wine | 2012 |
Elevated lipogenesis in epithelial stem-like cell confers survival advantage in ductal carcinoma in situ of breast cancer.
Topics: Animals; Apoptosis; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Lipogenesis; Mice; Mice, Nude; Resveratrol; Stem Cells; Sterol Regulatory Element Binding Protein 1; Stilbenes; Xenograft Model Antitumor Assays | 2013 |
Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.
Topics: Base Sequence; Cell Line; DNA Primers; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Liver; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Triiodothyronine | 2013 |
Resveratrol pre-treatment reduces early inflammatory responses induced by status epilepticus via mTOR signaling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Hippocampus; Inflammation; Male; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Status Epilepticus; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Resveratrol rescues SIRT1-dependent adult stem cell decline and alleviates progeroid features in laminopathy-based progeria.
Topics: Adult Stem Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Enzyme Activation; HEK293 Cells; Humans; Lamin Type A; Longevity; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Knockout; Nuclear Matrix; Nuclear Proteins; Progeria; Protein Binding; Protein Precursors; Recombinant Proteins; Resveratrol; Sirtuin 1; Stilbenes | 2012 |
Resveratrol affects the cross talk between immune and colon cancer cells.
Topics: Adult; Cell Line, Tumor; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; HT29 Cells; Humans; Interleukins; Leukocytes, Mononuclear; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
3,5,4'-Tri-O-acetylresveratrol attenuates seawater aspiration-induced lung injury by inhibiting activation of nuclear factor-kappa B and hypoxia-inducible factor-1α.
Topics: Animals; Antioxidants; Blotting, Western; Drowning; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Lung Injury; Male; NF-kappa B; Oxidative Stress; Prodrugs; Rats; Rats, Sprague-Dawley; Resveratrol; Seawater; Stilbenes | 2013 |
Resveratrol extends lifespan and preserves glia but not neurons of the Nothobranchius guentheri optic tectum.
Topics: Animals; Biomarkers; Cell Survival; Fishes; Glial Fibrillary Acidic Protein; Immunohistochemistry; Longevity; Neural Cell Adhesion Molecules; Neuroglia; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes; Superior Colliculi; Tenascin | 2013 |
Interventions: Live long and prosper.
Topics: Age of Onset; Aging; Animal Diseases; Animals; Biomedical Research; Caloric Restriction; Cardiovascular Diseases; Female; Gene Expression Profiling; Geriatrics; Humans; Longevity; Macaca mulatta; Male; Mice; Models, Animal; Neoplasms; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Resveratrol; Sirolimus; Sirtuins; Somatomedins; Stilbenes; TOR Serine-Threonine Kinases | 2012 |
In vitro antileishmanial activity of resveratrol originates from its cytotoxic potential against host cells.
Topics: Animals; Antiprotozoal Agents; Cells, Cultured; Cytotoxins; Female; Leishmania major; Macrophages; Mice; Nitric Oxide; Resveratrol; Stilbenes | 2013 |
Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibrosis; Glucose Tolerance Test; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Male; Mice; Organ Size; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Mitochondrial function is involved in regulation of cholesterol efflux to apolipoprotein (apo)A-I from murine RAW 264.7 macrophages.
Topics: Animals; Antimycin A; Apolipoproteins A; Atherosclerosis; Cell Line; Cell Survival; Cholesterol; Cholesterol Esters; DNA, Mitochondrial; Macrophages; Membrane Potential, Mitochondrial; Mice; Mitochondria; Nigericin; Oligomycins; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes | 2012 |
Resveratrol induces MMP-9 and cell migration via the p38 kinase and PI-3K pathways in HT1080 human fibrosarcoma cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Fibrosarcoma; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2013 |
Structure and expression profiling of a novel calcium-dependent protein kinase gene, CDPK3a, in leaves, stems, grapes, and cell cultures of wild-growing grapevine Vitis amurensis Rupr.
Topics: Base Sequence; Biomass; Cell Culture Techniques; DNA, Complementary; Fruit; Gene Expression; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Inflorescence; Molecular Sequence Data; Phylogeny; Plant Leaves; Plant Proteins; Plant Stems; Plants, Genetically Modified; Protein Kinases; Resveratrol; RNA, Plant; Salts; Seeds; Sequence Analysis, DNA; Stilbenes; Stress, Physiological; Temperature; Vitis | 2013 |
Statin administration does not improve the mobilization of very small embryonic-like stem cells (VSELs) in contrast to resveratrol treatment in a murine model of acute myocardial infarction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Combined Modality Therapy; Embryonic Stem Cells; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Resveratrol; Stem Cell Transplantation; Stilbenes; Treatment Outcome | 2012 |
Effects of resveratrol on incisional wound healing in rats.
Topics: Abdomen; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Fascia; Female; Fibroblasts; Granulation Tissue; Hydroxyproline; Laparotomy; Nitric Oxide; Nitric Oxide Synthase Type III; Postoperative Period; Preoperative Care; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tensile Strength; Time Factors; Vascular Endothelial Growth Factor A; Wound Healing | 2013 |
Generation of monoclonal antibody against trans-resveratrol.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antibody Specificity; Antigens; Calibration; Enzyme-Linked Immunosorbent Assay; Female; Haptens; Hybridomas; Mice; Mice, Inbred BALB C; Ovalbumin; Resveratrol; Serum Albumin, Bovine; Stilbenes | 2012 |
Nitric oxide scavenging rates of solubilized resveratrol and flavonoids.
Topics: Flavonoids; Free Radical Scavengers; Molecular Structure; Nitric Oxide; Resveratrol; Solubility; Stilbenes | 2013 |
Effect of long-term piceatannol treatment on eNOS levels in cultured endothelial cells.
Topics: Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Resveratrol; RNA, Messenger; Stilbenes | 2013 |
Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.
Topics: Animal Feed; Animals; Cell Line, Tumor; Cell Survival; Diet; Humans; Immunohistochemistry; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Knockout; Multiprotein Complexes; Mutation; Phosphorylation; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Resveratrol; Ribosomal Protein S6 Kinases; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles; Time Factors; TOR Serine-Threonine Kinases | 2013 |
Probing the binding sites of resveratrol, genistein, and curcumin with milk β-lactoglobulin.
Topics: Animals; Binding Sites; Binding, Competitive; Circular Dichroism; Curcumin; Genistein; Hydrophobic and Hydrophilic Interactions; Lactoglobulins; Milk; Milk Proteins; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Resveratrol; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Stilbenes; Thermodynamics | 2013 |
Resveratrol prevents EBV transformation and inhibits the outgrowth of EBV-immortalized human B cells.
Topics: Apoptosis; B-Lymphocytes; Blotting, Western; Cell Line, Transformed; Cell Transformation, Viral; Flow Cytometry; Herpesvirus 4, Human; Humans; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes | 2012 |
Differential proteomics identifies PDIA3 as a novel chemoprevention target in human colon cancer cells.
Topics: Anticarcinogenic Agents; Biomarkers, Tumor; Blotting, Western; Colonic Neoplasms; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Immunoprecipitation; Protein Disulfide-Isomerases; Proteomics; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Tumor Cells, Cultured | 2014 |
Long-term treatment with resveratrol attenuates oxidative stress pro-inflammatory mediators and apoptosis in streptozotocin-nicotinamide-induced diabetic rats.
Topics: Animals; Apoptosis; Cytokines; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Inflammation Mediators; Longitudinal Studies; Male; Niacinamide; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin; Treatment Outcome | 2012 |
SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cartilage, Articular; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Humans; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; NF-kappa B; Osteoarthritis, Knee; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Antioxidant cosmeto-textiles: skin assessment.
Topics: Adult; Animals; Antioxidants; Chromans; Cosmetics; Female; Humans; Organ Culture Techniques; Resveratrol; Skin; Skin Absorption; Stilbenes; Swine; Textiles | 2013 |
Resveratrol improves intrahepatic endothelial dysfunction and reduces hepatic fibrosis and portal pressure in cirrhotic rats.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension, Portal; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Nitric Oxide Synthase Type III; Portal Pressure; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thromboxane A2 | 2013 |
Stilbenoid profiles of canes from Vitis and Muscadinia species.
Topics: Benzofurans; Chromatography, High Pressure Liquid; Flavonoids; Glucosides; Magnetic Resonance Spectroscopy; Phenols; Resveratrol; Stilbenes; Vitis | 2013 |
Resveratrol attenuates the Na(+)-dependent intracellular Ca(2+) overload by inhibiting H(2)O(2)-induced increase in late sodium current in ventricular myocytes.
Topics: Acetanilides; Animals; Antioxidants; Arrhythmias, Cardiac; Calcium; Diastole; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Ventricles; Hydrogen Peroxide; Ischemia; Male; Muscle Cells; Patch-Clamp Techniques; Piperazines; Rabbits; Ranolazine; Resveratrol; Sodium; Stilbenes; Temperature; Tetrodotoxin | 2012 |
Resveratrol reduces prostate cancer growth and metastasis by inhibiting the Akt/MicroRNA-21 pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Enzyme Inhibitors; Estrogens; Flow Cytometry; Genes, Tumor Suppressor; Humans; Male; Mice; Mice, SCID; MicroRNAs; Morpholines; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Oligonucleotides; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Resveratrol; RNA, Small Interfering; Stilbenes; Wound Healing | 2012 |
Evidence for the analgesic activity of resveratrol in acute models of nociception in mice.
Topics: Analgesics; Animals; Behavior, Animal; Capsaicin; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Male; Mice; Molecular Structure; Nociception; Pain Measurement; Proto-Oncogene Proteins c-fos; Resveratrol; Stereoisomerism; Stilbenes | 2013 |
Novel Aza-resveratrol analogs: synthesis, characterization and anticancer activity against breast cancer cell lines.
Topics: Aza Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Estrogen Receptor alpha; Female; Gene Expression Regulation; Humans; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Binding; Resveratrol; Stilbenes | 2013 |
Resveratrol suppresses calcium-mediated microglial activation and rescues hippocampal neurons of adult rats following acute bacterial meningitis.
Topics: Animals; Calcium; Cerebrospinal Fluid; Cytokines; Hippocampus; Inflammation Mediators; Male; Meningitis, Bacterial; Microglia; Neurons; Neuroprotective Agents; Rats; Resveratrol; Stilbenes | 2013 |
Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Animals, Newborn; Apoptosis; Autophagy; Cells, Cultured; Densitometry; Energy Metabolism; Heart Failure; Heart Function Tests; Male; Mice; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase; TOR Serine-Threonine Kinases; Vacuoles; Ventricular Remodeling | 2013 |
Hepatic lipid metabolic pathways modified by resveratrol in rats fed an obesogenic diet.
Topics: Acetylation; Acyl-CoA Oxidase; Adenylate Kinase; Adipose Tissue; Animals; Carnitine O-Palmitoyltransferase; Diet, High-Fat; Dietary Sucrose; Enzyme Activation; Fatty Acids; Lipid Metabolism; Liver; Male; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Resveratrol; RNA-Binding Proteins; Sirtuin 1; Stilbenes; Transcription Factors; Triglycerides | 2013 |
Vaticaffinol, a resveratrol tetramer, exerts more preferable immunosuppressive activity than its precursor in vitro and in vivo through multiple aspects against activated T lymphocytes.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Dermatitis, Contact; Female; Immunosuppressive Agents; Lymphocyte Activation; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes; T-Lymphocytes | 2013 |
Amyloid aggregation of lysozyme: the synergy study of red wine polyphenols.
Topics: Amyloid; Animals; Antioxidants; Caffeic Acids; Chickens; Models, Molecular; Muramidase; Polyphenols; Quercetin; Resveratrol; Stilbenes; Wine | 2013 |
Resveratrol attenuates ischemia/reperfusion injury in neonatal cardiomyocytes and its underlying mechanism.
Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Calcium; Calcium-Transporting ATPases; Cardiotonic Agents; Caspase 3; Cell Survival; Gene Expression Regulation; Intracellular Space; L-Lactate Dehydrogenase; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes | 2012 |
Resveratrol prevents ammonia toxicity in astroglial cells.
Topics: Ammonia; Animals; Astrocytes; Cell Line; Cells, Cultured; Glutamate-Ammonia Ligase; Interleukin-1beta; Interleukin-6; NF-kappa B; Nitric Oxide; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2012 |
PKC activation by resveratrol derivatives with unsaturated aliphatic chain.
Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Fatty Acids; Humans; Isoenzymes; Models, Biological; Models, Molecular; Molecular Docking Simulation; Protein Kinase C-alpha; Protein Kinase C-epsilon; Resveratrol; Signal Transduction; Stilbenes; Structure-Activity Relationship | 2012 |
Neuroprotective effect of resveratrol prophylaxis on experimental retinal ischemic injury.
Topics: Animals; Cytoprotection; Disease Models, Animal; Electroretinography; Injections, Intraperitoneal; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Retina; Retinal Diseases; Stilbenes; Time Factors | 2013 |
Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation.
Topics: Antineoplastic Agents; Breast Neoplasms; Cytochrome P-450 CYP1A1; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Indoles; Ligands; MCF-7 Cells; Protein-Tyrosine Kinases; Pyrroles; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Stilbenes; Sunitinib; Transcriptional Activation | 2013 |
Modulation of bacterial ghosts--induced nitric oxide production in macrophages by bacterial ghost-delivered resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigen-Presenting Cells; Cell Membrane; Cell Survival; Cells, Cultured; Cytoplasm; Drug Delivery Systems; Escherichia coli; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Resveratrol; Stilbenes | 2013 |
Resveratrol suppresses tumor progression via the regulation of indoleamine 2,3-dioxygenase.
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Dendritic Cells; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Male; Mice; Mice, Inbred C57BL; Neoplasms; Proto-Oncogene Proteins c-akt; Resveratrol; STAT1 Transcription Factor; Stilbenes; Tumor Escape | 2013 |
A novel synthesized tyrosinase inhibitor: (E)-2-((2,4-dihydroxyphenyl)diazenyl)phenyl 4-methylbenzenesulfonate as an azo-resveratrol analog.
Topics: Animals; Azo Compounds; Benzenesulfonates; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Enzyme Assays; Enzyme Inhibitors; Fungal Proteins; Kinetics; Melanins; Melanoma, Experimental; Mice; Molecular Docking Simulation; Monophenol Monooxygenase; Pigmentation Disorders; Pyrones; Resveratrol; Stilbenes | 2013 |
Beneficial effects of grape resveratrol on serum adiponectin and inflammation: clinical trial in patients with stable coronary artery disease: editorial to: "Grape resveratrol increases serum adiponectin and downregulates inflammatory genes in peripheral
Topics: Adiponectin; Anti-Inflammatory Agents; Coronary Artery Disease; Female; Humans; Leukocytes, Mononuclear; Male; Resveratrol; Stilbenes; Transcription Factors; Vitis | 2013 |
Resveratrol protects against age-associated infertility in mice.
Topics: Aging; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Ectogenesis; Female; Gene Expression Regulation, Developmental; Infertility, Female; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Oogenesis; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Proto-Oncogene Proteins p21(ras); Random Allocation; Resveratrol; Sirtuin 1; Stilbenes; Telomerase; Telomere Shortening | 2013 |
Dose-dependent interaction of trans-resveratrol with biomembranes: effects on antioxidant property.
Topics: Antioxidants; Cell Membrane; Dose-Response Relationship, Drug; Humans; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Fluidity; Microscopy, Electron, Scanning; Models, Molecular; Resveratrol; Stilbenes | 2013 |
Activities of muscadine grape skin and polyphenolic constituents against Helicobacter pylori.
Topics: 1-Naphthylamine; Anti-Bacterial Agents; Cell Membrane Permeability; Helicobacter pylori; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Plant Extracts; Polyphenols; Quercetin; Resveratrol; Stilbenes; Vitis | 2013 |
Sirtuin 1 affects the transcriptional expression of adipose triglyceride lipase in porcine adipocytes.
Topics: Adipocytes; Animals; Cells, Cultured; Fluorescent Antibody Technique; Gene Knockdown Techniques; Lipase; Lipid Metabolism; Microscopy, Confocal; PPAR gamma; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Sus scrofa | 2013 |
Effect of wine polyphenol resveratrol on the contractions elicited electrically or by norepinephrine in the rat portal vein.
Topics: Adenosine Triphosphate; Animals; Calcium Chloride; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Portal Vein; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasoconstriction; Wine | 2013 |
Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 protein-mediated modulation of p300 protein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Cardiomyopathies; Down-Regulation; Dystrophin; E1A-Associated p300 Protein; Echocardiography; Male; Mice; Mice, Inbred C57BL; Models, Biological; Phenylephrine; Proteasome Endopeptidase Complex; Resveratrol; Sirtuin 1; Stilbenes; Ubiquitin | 2013 |
The protective effects of oxyresveratrol imine derivative against hydrogen peroxide-induced cell death in PC12 cells.
Topics: Animals; Antioxidants; Apoptosis; Cell Nucleus; Enzyme Induction; Extracellular Signal-Regulated MAP Kinases; Heme Oxygenase-1; Hydrogen Peroxide; Imines; NF-E2-Related Factor 2; Oxidants; Oxidation-Reduction; PC12 Cells; Phosphorylation; Plant Extracts; Protein Processing, Post-Translational; Protein Transport; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Up-Regulation | 2013 |
Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Immunologic Deficiency Syndromes; Mice; Mice, Hairless; Mice, Nude; Neoplasm Metastasis; p21-Activated Kinases; Plant Extracts; Polyphenols; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Resveratrol; Stilbenes; Vitis | 2013 |
Mixed lipid phase SMEDDS as an innovative approach to enhance resveratrol solubility.
Topics: Antioxidants; Chemistry, Pharmaceutical; Drug Compounding; Drug Delivery Systems; Drug Stability; Drug Storage; Emulsions; Lipids; Particle Size; Phase Transition; Resveratrol; Solubility; Stilbenes; Surface-Active Agents; Time Factors; Viscosity | 2014 |
[Resveratrol attenuates oxidant-induced mitochondrial damage in embryonic rat cardiomyocytes via inactivating GSK-3β].
Topics: Animals; Carbazoles; Cell Line; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydrogen Peroxide; Mitochondria, Heart; Myocytes, Cardiac; Oxidants; Rats; Resveratrol; Signal Transduction; Stilbenes | 2012 |
Binding sites of resveratrol, genistein, and curcumin with milk α- and β-caseins.
Topics: Animals; Antioxidants; Binding Sites; Caseins; Curcumin; Genistein; Milk; Molecular Docking Simulation; Protein Stability; Protein Structure, Secondary; Resveratrol; Spectrum Analysis; Stilbenes; Water | 2013 |
Prophylactic effect of resveratrol against ethinylestradiol-induced liver cholestasis.
Topics: Animals; Antioxidants; Bile Acids and Salts; Bilirubin; Cholestasis; Cholesterol; Ethinyl Estradiol; Female; Hepatocytes; Liver; Liver Diseases; Malondialdehyde; Nitric Oxide; Phytotherapy; Plant Extracts; Rats; Rats, Inbred Strains; Resveratrol; Stilbenes; Sulfhydryl Compounds; Tumor Necrosis Factor-alpha | 2013 |
Ultra high performance liquid chromatography-quadrupole-time of flight analysis for the identification and the determination of resveratrol and its metabolites in mouse plasma.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry; Mice; Resveratrol; Sensitivity and Specificity; Stilbenes; Time Factors | 2013 |
Neuroprotective effects of resveratrol on embryonic dorsal root ganglion neurons with neurotoxicity induced by ethanol.
Topics: Animals; Cells, Cultured; Ethanol; Ganglia, Spinal; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits human nasopharyngeal carcinoma cell growth via blocking pAkt/p70S6K signaling pathways.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclins; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2013 |
Resveratrol directly affects in vitro lipolysis and glucose transport in human fat cells.
Topics: Adipocytes; Adult; Antioxidants; Benzylamines; Biological Transport; Female; Glucose; Glycerol; Humans; Insulin; Isoproterenol; Lipogenesis; Lipolysis; Overweight; Primary Cell Culture; Resveratrol; Stilbenes; Subcutaneous Fat | 2013 |
Neuroprotective effects of resveratrol against Aβ administration in rats are improved by lipid-core nanocapsules.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; beta Catenin; Cytoprotection; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Injections, Intraventricular; JNK Mitogen-Activated Protein Kinases; Lipids; Male; Memory Disorders; Microglia; Nanocapsules; Neuroprotective Agents; Protein Stability; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Synapses; Tissue Distribution | 2013 |
Resveratrol prevents global cerebral ischemia-induced decrease in lipid content.
Topics: Animals; Antioxidants; Brain Ischemia; Cholesterol; Chromatography, Thin Layer; Disease Models, Animal; Gangliosidoses; Lipid Metabolism Disorders; Male; Phospholipids; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Photoprotective activity of resveratrol analogues.
Topics: Humans; Resveratrol; Skin; Stilbenes; Structure-Activity Relationship; Sun Protection Factor; Sunscreening Agents; Ultraviolet Rays | 2013 |
Oxidative stress and DNA damage signalling in skeletal muscle in pressure-induced deep tissue injury.
Topics: Animals; Apoptosis; Catalase; Cell Nucleus; DNA Damage; DNA Repair Enzymes; Female; Glutathione Peroxidase; Hindlimb; Muscle, Skeletal; Myofibrils; Nitric Oxide Synthase Type II; Oxidative Stress; Phosphorylation; Pressure; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Transcription, Genetic; Tumor Suppressor Protein p53 | 2013 |
Novel resveratrol nanodelivery systems based on lipid nanoparticles to enhance its oral bioavailability.
Topics: Analysis of Variance; Biological Availability; Calorimetry, Differential Scanning; Drug Carriers; Drug Stability; Lipids; Models, Biological; Nanoparticles; Nanotechnology; Particle Size; Resveratrol; Stilbenes; Temperature | 2013 |
Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway.
Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1beta; Male; Matrix Metalloproteinase 3; Middle Aged; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Synovial Membrane; Tumor Necrosis Factor-alpha | 2013 |
Resveratrol attenuates hydrogen peroxide-induced apoptosis in human umbilical vein endothelial cells.
Topics: Apoptosis; Cell Survival; Cells, Cultured; Glutathione; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis.
Topics: Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Animals; Cell Line; Cell Nucleus; Immunoblotting; Mice; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; Mitochondria, Muscle; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; Physical Conditioning, Animal; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Trans-Activators; Transcription Factors; Vasodilator Agents | 2013 |
The effect of sulfated (1→3)-α-l-fucan from the brown alga Saccharina cichorioides Miyabe on resveratrol-induced apoptosis in colon carcinoma Cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Caspases; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; HCT116 Cells; Humans; Magnetic Resonance Spectroscopy; Phaeophyceae; Polysaccharides; Resveratrol; Stilbenes; Sulfuric Acid Esters | 2013 |
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice.
Topics: Animals; Atherosclerosis; Atorvastatin; Biomarkers; Cholesterol, Dietary; Cholesterol, LDL; Drug Synergism; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Mice; Mice, Transgenic; Oxidative Stress; Pyrroles; Resveratrol; Stilbenes | 2013 |
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol.
Topics: Atrazine; Cell Line; Cell Survival; Chorionic Gonadotropin; Diethylstilbestrol; Environmental Pollutants; Estradiol; Estrogens; Humans; Phenols; Resveratrol; Stilbenes; Trophoblasts | 2013 |
Comparision of piceid and resveratrol in antioxidation and antiproliferation activities in vitro.
Topics: Antioxidants; Cell Line, Tumor; Cell Proliferation; Glucosides; Hep G2 Cells; Humans; Resveratrol; Stilbenes | 2013 |
Resveratrol down-regulates Myosin light chain kinase, induces apoptosis and inhibits diethylnitrosamine-induced liver tumorigenesis in rats.
Topics: Alkylating Agents; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Diethylnitrosamine; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Liver Neoplasms, Experimental; Male; Myosin-Light-Chain Kinase; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet.
Topics: Animals; Cell Line, Tumor; Cellular Senescence; Diet, High-Fat; Humans; Hyperinsulinism; Hypoxia-Inducible Factor 1, alpha Subunit; Insulin; Insulin Resistance; Male; Mice; Obesity; Resveratrol; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Transcription, Genetic; Weight Gain | 2013 |
Pharmacokinetics, tissue distribution and excretion study of resveratrol and its prodrug 3,5,4'-tri-O-acetylresveratrol in rats.
Topics: Animals; Area Under Curve; Feces; Half-Life; Heart; Liver; Lung; Male; Myocardium; Prodrugs; Rats; Rats, Sprague-Dawley; Resveratrol; Spleen; Stilbenes; Tissue Distribution | 2013 |
[Protective effect of propofol and resveratrol pretreatment against hepatocyte apoptosis in rats with hepatic ischemia-reperfusion injury].
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Hepatocytes; Ischemic Preconditioning; Liver Diseases; Male; Propofol; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2013 |
Synthesis and biological evaluation of some novel resveratrol amide derivatives as potential anti-tumor agents.
Topics: Amides; Animals; Antineoplastic Agents; Cell Line; Cell Proliferation; Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mice; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
Resveratrol decreases inflammation in the brain of mice with mild traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Disease Models, Animal; Encephalitis; Enzyme-Linked Immunosorbent Assay; Hippocampus; Interleukin-12; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Microglia; Resveratrol; Stilbenes | 2013 |
Induction of apoptosis in HeLa cells via caspase activation by resveratrol and genistein.
Topics: Apoptosis; Caspase 3; Caspase 9; Enzyme Activation; Genistein; HeLa Cells; Humans; Proto-Oncogene Proteins c-mdm2; Resveratrol; Stilbenes | 2013 |
Resveratrol protects HUVECs from oxidized-LDL induced oxidative damage by autophagy upregulation via the AMPK/SIRT1 pathway.
Topics: AMP-Activated Protein Kinases; Antioxidants; Autophagy; Blotting, Western; Cell Culture Techniques; Cell Membrane; Cell Survival; Cytoplasm; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Microscopy, Electron, Transmission; Oxidative Stress; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase; Up-Regulation | 2013 |
Resveratrol induces apoptosis of pancreatic cancers cells by inhibiting miR-21 regulation of BCL-2 expression.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Pancreatic Ducts; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
Assessing the regioselectivity of OleD-catalyzed glycosylation with a diverse set of acceptors.
Topics: Bacterial Proteins; Catalysis; Glucosides; Glucosyltransferases; Glycosylation; Isoflavones; Resveratrol; Stereoisomerism; Stilbenes; Streptomyces antibioticus | 2013 |
Resveratrol and adipose-derived mesenchymal stem cells are effective in the prevention and treatment of doxorubicin cardiotoxicity in rats.
Topics: Adipose Tissue; Animals; Antibiotics, Antineoplastic; Cell Proliferation; Doxorubicin; Female; Heart Diseases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
SIRT1 regulates the human alveolar epithelial A549 cell apoptosis induced by Pseudomonas aeruginosa lipopolysaccharide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Epithelial Cells; Humans; Lipopolysaccharides; Niacinamide; Proto-Oncogene Proteins c-bcl-2; Pseudomonas aeruginosa; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2013 |
Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
Topics: Adaptor Proteins, Signal Transducing; Aspirin; Ataxia Telangiectasia Mutated Proteins; Berberine; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Cholecalciferol; Deoxyglucose; DNA Damage; DNA-Binding Proteins; Down-Regulation; Enzyme Activation; Flow Cytometry; Histones; Humans; Laser Scanning Cytometry; Membrane Potential, Mitochondrial; Metformin; Mitochondria; Oxidative Stress; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins | 2012 |
Cerebroprotective potential of resveratrol through anti-oxidant and anti-inflammatory mechanisms in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Brain Ischemia; Cerebral Infarction; Male; Neuroprotective Agents; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Resveratrol induces cell cycle arrest and apoptosis in malignant NK cells via JAK2/STAT3 pathway inhibition.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Asparaginase; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Humans; Janus Kinase 2; Killer Cells, Natural; Leukemia, Large Granular Lymphocytic; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tumor Suppressor Protein p53 | 2013 |
Effect of dietary resveratrol on the metabolic profile of nutrients in obese OLETF rats.
Topics: Adipose Tissue, White; Animals; Body Weight; Carnitine O-Palmitoyltransferase; Cholesterol; Food, Formulated; Gene Expression; Glycogen; Lipid Metabolism; Liver; Male; Metabolome; Obesity; Rats; Rats, Inbred OLETF; Resveratrol; RNA, Messenger; Stilbenes; Triglycerides; Up-Regulation | 2013 |
A DFT method for the study of the antioxidant action mechanism of resveratrol derivatives.
Topics: Algorithms; Antioxidants; Models, Chemical; Molecular Conformation; Oxidation-Reduction; Resveratrol; Stilbenes | 2013 |
Oil, fatty acid, flavonoid, and resveratrol content variability and FAD2A functional SNP genotypes in the U.S. peanut mini-core collection.
Topics: Arachis; Fatty Acid Desaturases; Fatty Acids; Flavonoids; Genotype; Plant Extracts; Plant Oils; Polymorphism, Single Nucleotide; Resveratrol; Seeds; Stilbenes; United States | 2013 |
Resveratrol decreases noise-induced cyclooxygenase-2 expression in the rat cochlea.
Topics: Animals; Antioxidants; Cochlea; Cyclooxygenase 2; Hearing Loss, Noise-Induced; Male; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2013 |
Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1.
Topics: Amyloid beta-Peptides; Animals; Caspase 3; Catechin; Cell Line, Tumor; Cell Membrane; Hippocampus; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Membrane Microdomains; Microscopy, Fluorescence; Neurons; Prions; Protein Binding; Proto-Oncogene Proteins c-fyn; Rats; Rats, Wistar; Resveratrol; RNA Interference; Stilbenes; Tea | 2013 |
Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells.
Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Carbon Radioisotopes; Cholesterol; Drug Synergism; Endometrium; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Primary Cell Culture; Resveratrol; RNA, Messenger; Simvastatin; Stilbenes; Stromal Cells | 2013 |
Production of phytoalexins in peanut (Arachis hypogaea) seed elicited by selected microorganisms.
Topics: Arachis; Bacterial Physiological Phenomena; Fungi; Phytoalexins; Resveratrol; Seeds; Sesquiterpenes; Stilbenes | 2013 |
Preparation and investigation of LC packing made by microwave-assisted solid-phase synthesis.
Topics: Adsorption; Chromatography, High Pressure Liquid; Microwaves; Peptides; Polymers; Resins, Synthetic; Resveratrol; Solid-Phase Synthesis Techniques; Stilbenes; Wine | 2013 |
Resveratrol improves sperm motility, prevents lipid peroxidation and enhances antioxidant defences in the testes of hyperthyroid rats.
Topics: Animals; Antioxidants; Catalase; Epididymis; Glutathione Peroxidase; Glutathione Transferase; Hyperthyroidism; Lipid Peroxidation; Male; Organ Size; Oxidative Stress; Prostate; Rats; Rats, Wistar; Resveratrol; Sperm Motility; Stilbenes; Testis; Thiobarbituric Acid Reactive Substances | 2013 |
The role of aryl hydrocarbon receptor signaling pathway in cardiotoxicity of acute lead intoxication in vivo and in vitro rat model.
Topics: Animals; Blotting, Western; Creatine Kinase; Cytochrome P-450 CYP1A1; Heart; Heart Diseases; Histocytochemistry; L-Lactate Dehydrogenase; Lead; Male; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Random Allocation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes | 2013 |
Significant longevity-extending effects of Alpinia zerumbet leaf extract on the life span of Caenorhabditis elegans.
Topics: Alpinia; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dose-Response Relationship, Drug; Free Radical Scavengers; Gene Expression; Heat-Shock Proteins; Hot Temperature; Longevity; Oxidative Stress; Plant Extracts; Plant Leaves; Quercetin; Resveratrol; Solvents; Stilbenes; Superoxide Dismutase | 2013 |
SIRT1 regulates the neurogenic potential of neural precursors in the adult subventricular zone and hippocampus.
Topics: Analysis of Variance; Animals; Bromodeoxyuridine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cerebral Ventricles; Dose-Response Relationship, Drug; Doublecortin Domain Proteins; Enzyme Inhibitors; Green Fluorescent Proteins; Hippocampus; Ki-67 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microtubule-Associated Proteins; Neural Stem Cells; Neurogenesis; Neuropeptides; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stem Cell Niche; Stilbenes; Transfection; Tubulin | 2013 |
Resveratrol improves diabetic retinopathy possibly through oxidative stress - nuclear factor κB - apoptosis pathway.
Topics: Administration, Oral; Animals; Antioxidants; Apoptosis; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glutathione; Glycated Hemoglobin; Insulin; Lipid Peroxidation; Male; NF-kappa B; Niacinamide; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Retina; Signal Transduction; Stilbenes; Streptozocin; Superoxide Dismutase; Time Factors | 2012 |
Modulation of TRP channels by resveratrol and other stilbenoids.
Topics: Animals; Behavior, Animal; Capsaicin; Ganglia, Spinal; HEK293 Cells; Humans; Ion Channel Gating; Isothiocyanates; Male; Mice; Nociception; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transfection; Transient Receptor Potential Channels | 2013 |
Age-related oxidative modifications of transthyretin modulate its amyloidogenicity.
Topics: Age Factors; Aging; Amyloid; Amyloidosis; Benzothiazoles; Cell Line; Humans; Myocytes, Cardiac; Oxidation-Reduction; Point Mutation; Prealbumin; Protein Carbonylation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Resveratrol; Stilbenes; Thiazoles | 2013 |
Microarray analysis of the inflammatory and immune responses in head kidney turbot leucocytes treated with resveratrol.
Topics: Animals; Antigens, Protozoan; Cells, Cultured; Ciliophora; Flatfishes; Gene Expression Regulation; Head Kidney; Heme Oxygenase-1; Immunity; Inflammation; Inflammation Mediators; Leukocytes; Microarray Analysis; Proto-Oncogene Proteins; Resveratrol; S100 Proteins; STAT4 Transcription Factor; Stilbenes; Trans-Activators | 2013 |
trans-Resveratrol protects ischemic PC12 Cells by inhibiting the hypoxia associated transcription factors and increasing the levels of antioxidant defense enzymes.
Topics: Animals; Antioxidants; Calcium; Calcium Channels; Cell Death; Cell Hypoxia; HSP27 Heat-Shock Proteins; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; L-Lactate Dehydrogenase; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; STAT3 Transcription Factor; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; TRPM Cation Channels | 2013 |
Resveratrol enhances exercise training responses in rats selectively bred for high running performance.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Biomarkers; DNA-Binding Proteins; Insulin Resistance; Male; Mitochondria; Mitochondrial Proteins; Oxidative Stress; Physical Conditioning, Animal; Protein Carbonylation; Rats; Reactive Oxygen Species; Resveratrol; Running; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging.
Topics: Acetylation; Aging; Animals; Aorta, Thoracic; Caveolins; Cyclic GMP; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; RNA-Binding Proteins; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors; Vasodilation; Vasodilator Agents | 2013 |
Resveratrol abrogates alcohol-induced cognitive deficits by attenuating oxidative-nitrosative stress and inflammatory cascade in the adult rat brain.
Topics: Acetylcholinesterase; Animals; Antioxidants; Anxiety; Catalase; Central Nervous System Depressants; Cognition Disorders; Encephalitis; Ethanol; Glutathione; Interleukin-1beta; Lipid Peroxidation; Male; Maze Learning; Memory; Motor Activity; NF-kappa B; Nitrites; Oxidative Stress; Rats; Rats, Wistar; Reactive Nitrogen Species; Resveratrol; Stilbenes; Stress, Physiological; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidation.
Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Glutathione Transferase; Lipid Peroxidation; Male; Methotrexate; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2013 |
[Antagonizing effect of resveratrol on the lipid peroxidative damage induced by lead in mice].
Topics: Animals; Antioxidants; Catalase; Glutathione Peroxidase; Lead; Lipid Peroxidation; Male; Malondialdehyde; Mice; Resveratrol; Stilbenes; Superoxide Dismutase | 2012 |
Effects of estrogen and phytoestrogens on endometrial leakage in ovariectomized rats and the related mechanisms.
Topics: Animals; Endothelium, Vascular; Eosinophils; Estradiol; Estrogens; Female; Genistein; NF-kappa B; Ovariectomy; Permeability; Phloretin; Phytoestrogens; Progesterone; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Uterus; Vascular Endothelial Growth Factor A | 2013 |
Resveratrol is a potent inhibitor of vascularization and cell proliferation in experimental endometriosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Female; Image Processing, Computer-Assisted; Immunohistochemistry; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Platelet Endothelial Cell Adhesion Molecule-1; Resveratrol; Stilbenes; Time Factors | 2013 |
Resveratrol attenuates oxidative stress induced by balloon injury in the rat carotid artery through actions on the ERK1/2 and NF-kappa B pathway.
Topics: Animals; Antioxidants; Aorta, Thoracic; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cells, Cultured; Chemokine CCL2; Dinoprost; Disease Models, Animal; Interleukin-6; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; NADPH Oxidases; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor RelA; Transcription, Genetic | 2013 |
The inhibition of resveratrol to human skin squamous cell carcinoma A431 xenografts in nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Body Weight; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Phytotherapy; Plant Extracts; Repressor Proteins; Resveratrol; RNA, Messenger; Skin Neoplasms; Stilbenes; Survivin; Transplantation, Heterologous; Tumor Suppressor Protein p53; Veratrum | 2013 |
Resveratrol and quercetin-induced apoptosis of human 232B4 chronic lymphocytic leukemia cells by activation of caspase-3 and cell cycle arrest.
Topics: Annexin A5; Apoptosis; B-Lymphocytes; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Cytotoxins; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Quercetin; Resveratrol; Stilbenes | 2013 |
Effects of glycine, pyruvate, resveratrol, and nitrite on tissue injury and cytokine response in endotoxemic rats.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Electrolytes; Endotoxemia; Glycine; Hematocrit; Hemoglobins; Lipopolysaccharides; Male; Pyruvic Acid; Rats; Rats, Wistar; Resveratrol; Sodium Nitrite; Stilbenes | 2013 |
Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways.
Topics: Animals; Calpain; Cyclic AMP Response Element-Binding Protein; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Signal Transduction; Stilbenes; TRPC Cation Channels | 2013 |
Resveratrol mitigates genotoxicity induced by iodine-131 in primary human lymphocytes.
Topics: Adult; Cells, Cultured; Humans; Iodine Radioisotopes; Lymphocytes; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens; Radiation-Protective Agents; Resveratrol; Stilbenes | 2013 |
The antimetastatic effects of resveratrol on hepatocellular carcinoma through the downregulation of a metastasis-associated protease by SP-1 modulation.
Topics: Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Neoplasm Invasiveness; Phosphorylation; Resveratrol; Signal Transduction; Sp1 Transcription Factor; Stilbenes; Urokinase-Type Plasminogen Activator | 2013 |
Resveratrol activates SIRT1 in a Lamin A-dependent manner.
Topics: Adult Stem Cells; Aging, Premature; Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Histone Deacetylases; Humans; Lamin Type A; Membrane Proteins; Metalloendopeptidases; Mice; Mice, Knockout; Nuclear Matrix; Nuclear Proteins; Progeria; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Ataxia-telangiectasia mutated kinase-mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility.
Topics: Anticarcinogenic Agents; Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; DNA-Binding Proteins; Flow Cytometry; Humans; Killer Cells, Natural; Leukemia; Ligands; NK Cell Lectin-Like Receptor Subfamily K; Protein Serine-Threonine Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Tumor Suppressor Proteins; Up-Regulation | 2013 |
Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Curcumin; Down-Regulation; Drug Synergism; Inhibitor of Apoptosis Proteins; Liver Neoplasms, Experimental; Mice; Reactive Oxygen Species; Repressor Proteins; Resveratrol; Stilbenes; Survivin; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2013 |
Drug absorption efficiency in Caenorhbditis elegans delivered by different methods.
Topics: Absorption; Animals; Caenorhabditis elegans; Resveratrol; Solubility; Stilbenes | 2013 |
Resveratrol decreases breast cancer cell viability and glucose metabolism by inhibiting 6-phosphofructo-1-kinase.
Topics: Antioxidants; Breast Neoplasms; Cell Survival; Female; Glucose; Humans; MCF-7 Cells; Phosphofructokinase-1; Protein Kinase Inhibitors; Resveratrol; Stilbenes | 2013 |
Regulatory effects of resveratrol on antioxidant enzymes: a mechanism of growth inhibition and apoptosis induction in cancer cells.
Topics: Anticarcinogenic Agents; Apoptosis; Catalase; Cell Proliferation; Gene Expression; Gene Expression Regulation, Neoplastic; Glutathione Peroxidase; HEK293 Cells; Hep G2 Cells; Humans; Hydrogen Peroxide; MCF-7 Cells; Resveratrol; Stilbenes; Superoxide Dismutase; Up-Regulation | 2013 |
Inhibitory effects of resveratrol on PDGF-BB-induced retinal pigment epithelial cell migration via PDGFRβ, PI3K/Akt and MAPK pathways.
Topics: Becaplermin; Cell Adhesion; Cell Line; Cell Movement; Cell Survival; Enzyme Activation; Gene Expression Regulation; Humans; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor beta; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2013 |
Protective effects of resveratrol on glutamate-induced damages in murine brain cultures.
Topics: Animals; Antioxidants; Biphenyl Compounds; Brain; Cells, Cultured; Coloring Agents; Copper; Ethidium; Excitatory Amino Acid Antagonists; Female; Fluorescent Dyes; Glutamic Acid; Iron; Mesencephalon; Mice; Mice, Inbred C57BL; Neurites; Neurons; Organ Culture Techniques; Picrates; Pregnancy; Propidium; Resveratrol; Spectrophotometry, Atomic; Stilbenes; Tetrazolium Salts; Thiazoles; Tyrosine 3-Monooxygenase | 2013 |
A dietary polyphenol resveratrol acts to provide neuroprotection in recurrent stroke models by regulating AMPK and SIRT1 signaling, thereby reducing energy requirements during ischemia.
Topics: Age Factors; AMP-Activated Protein Kinases; Animals; Cerebral Cortex; Diet; Energy Metabolism; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; NAD; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Stroke | 2013 |
Effects of resveratrol on topoisomerase II-α activity: induction of micronuclei and inhibition of chromosome segregation in CHO-K1 cells.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; CHO Cells; Chromosome Deletion; Chromosome Segregation; Cricetinae; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Micronuclei, Chromosome-Defective; Mitosis; Polyploidy; Resveratrol; Stilbenes | 2013 |
Potential chemoprevention activity of pterostilbene by enhancing the detoxifying enzymes in the HT-29 cell line.
Topics: Cell Line, Tumor; Chemoprevention; Colonic Neoplasms; Glutathione; Glutathione Transferase; HT29 Cells; Humans; Inactivation, Metabolic; NAD(P)H Dehydrogenase (Quinone); Resveratrol; Stilbenes | 2012 |
Anti-estrogenic activity of a human resveratrol metabolite.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Clone Cells; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Glucosides; Glucuronides; Humans; MCF-7 Cells; Neoplasm Proteins; Nuclear Receptor Coactivator 2; Peptide Fragments; Phytoestrogens; Recombinant Proteins; Resveratrol; Stereoisomerism; Stilbenes; Sulfates | 2013 |
The potent relaxant effect of resveratrol in rat corpus cavernosum and its underlying mechanisms.
Topics: Animals; Cyclic GMP; Drug Synergism; Endothelium, Vascular; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Penis; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Sildenafil Citrate; Stilbenes; Sulfones; Vasodilator Agents | 2013 |
Resveratrol has inhibitory effects on the hypoxia-induced inflammation and angiogenesis in human adipose tissue in vitro.
Topics: Adipose Tissue; Adult; Angiogenesis Inhibitors; Anti-Inflammatory Agents; Female; Glucose Transporter Type 1; Humans; Hypoxia; In Vitro Techniques; Inflammation; Interleukin-6; Interleukin-8; Leptin; Neovascularization, Physiologic; Resveratrol; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor growth, progression and metastasis in prostate cancer.
Topics: Acetylation; Animals; Antineoplastic Agents, Phytogenic; Disease Progression; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Luciferases; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mice; Neoplasm Metastasis; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators; Transcription Factors; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Resveratrol protects against arsenic trioxide-induced nephrotoxicity by facilitating arsenic metabolism and decreasing oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Arsenic Trioxide; Arsenicals; Blood Urea Nitrogen; Catalase; Cats; Creatinine; Cytoprotection; Deoxyguanosine; Glutathione; Glutathione Peroxidase; Injections, Intravenous; Kidney; Kidney Diseases; Malondialdehyde; Oxidative Stress; Oxides; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Biochemistry. Red wine, toast of the town (again).
Topics: Animals; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Evidence for a common mechanism of SIRT1 regulation by allosteric activators.
Topics: Allosteric Regulation; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Activation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glutamic Acid; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Molecular Sequence Data; Myoblasts; Protein Structure, Tertiary; Resveratrol; Sirtuin 1; Stilbenes; Substrate Specificity | 2013 |
Pulmonary metabolism of resveratrol: in vitro and in vivo evidence.
Topics: Animals; In Vitro Techniques; Lung; Male; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes | 2013 |
Azastilbene analogs as tyrosinase inhibitors: new molecules with depigmenting potential.
Topics: Agaricales; Antioxidants; Enzyme Inhibitors; Fungal Proteins; Molecular Conformation; Monophenol Monooxygenase; Phenols; Pyrones; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors | 2013 |
Hydrogenosome metabolism is the key target for antiparasitic activity of resveratrol against Trichomonas vaginalis.
Topics: Animals; Antitrichomonal Agents; Female; Humans; Hydrogen; Hydrogenase; Iron-Sulfur Proteins; Organelles; Parasitic Sensitivity Tests; Pyruvate Synthase; Resveratrol; Stilbenes; Trichomonas vaginalis; Trichomonas Vaginitis; Up-Regulation | 2013 |
SIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1.
Topics: Adventitia; Animals; Apoptosis; Endothelium, Vascular; Fibroblasts; Forkhead Transcription Factors; Gene Knockdown Techniques; Nerve Tissue Proteins; Rats; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Preparation of magnetic molecularly imprinted polymer for selective recognition of resveratrol in wine.
Topics: Adsorption; Chromatography, High Pressure Liquid; Limit of Detection; Linear Models; Magnetite Nanoparticles; Molecular Imprinting; Polymers; Reproducibility of Results; Resveratrol; Solid Phase Extraction; Stilbenes; Wine | 2013 |
Creation of resveratrol-enriched rice for the treatment of metabolic syndrome and related diseases.
Topics: Acyltransferases; Adipose Tissue; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Female; Food, Fortified; Glucosides; Glucosyltransferases; Humans; Lipids; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Oryza; Plant Leaves; Plants, Genetically Modified; Resveratrol; Seeds; Sirtuin 1; Stilbenes | 2013 |
Neurodegeneration in streptozotocin-induced diabetic rats is attenuated by treatment with resveratrol.
Topics: Animals; Antioxidants; Astrocytes; Blood-Brain Barrier; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Hippocampus; Male; Nerve Degeneration; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Streptozocin | 2013 |
Resveratrol decreases periodontal breakdown and modulates local levels of cytokines during periodontitis in rats.
Topics: Alveolar Bone Loss; Animals; Biofilms; Cytokines; Disease Models, Animal; Disease Progression; Gingiva; Immunologic Factors; Interleukin-17; Interleukin-1beta; Interleukin-4; Male; Periodontitis; Placebos; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Pre-column incubation followed by fast liquid chromatography analysis for rapid screening of natural methylglyoxal scavengers directly from herbal medicines: case study of Polygonum cuspidatum.
Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Glycation End Products, Advanced; Humans; Hydrogen-Ion Concentration; Mass Spectrometry; Plant Preparations; Pyruvaldehyde; Resveratrol; Serum Albumin; Stilbenes | 2013 |
Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Ceramides; Cyclooxygenase 2; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Nitrobenzenes; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; RNA, Small Interfering; Stilbenes; Sulfonamides; Tumor Suppressor Protein p53 | 2013 |
Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Synergism; Glucuronides; Humans; Resveratrol; Stilbenes | 2013 |
Acute effects of resveratrol to enhance cocaine-induced dopamine neurotransmission in the striatum.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; In Vitro Techniques; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Neostriatum; Phosphorylation; Resveratrol; Stilbenes; Synaptic Transmission | 2013 |
Synthesis and evaluation of resveratrol derivatives as new chemical entities for cancer.
Topics: Actins; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; DNA Fragmentation; DNA, Neoplasm; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Molecular Docking Simulation; NF-kappa B; Protein Binding; Receptors, Tumor Necrosis Factor; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Vitis vinifera secondary metabolism as affected by sulfate depletion: diagnosis through phenylpropanoid pathway genes and metabolites.
Topics: Acyltransferases; Anthocyanins; Cell Culture Techniques; Chlorophyll; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Genes, Plant; Plant Cells; Plant Proteins; Resveratrol; RNA, Messenger; Stilbenes; Sulfur; Transcription, Genetic; Up-Regulation; Vitis | 2013 |
Autophagy is involved in the effects of resveratrol on prevention of splenocyte apoptosis caused by oxidative stress in restrained mice.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Ascorbic Acid; Autophagy; Beclin-1; In Situ Nick-End Labeling; Male; Membrane Potential, Mitochondrial; Mice; Microtubule-Associated Proteins; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirolimus; Spleen; Stilbenes; T-Lymphocyte Subsets; Up-Regulation | 2013 |
Resveratrol inhibits IgE-mediated basophilic mast cell degranulation and passive cutaneous anaphylaxis in mice.
Topics: Anaphylaxis; Animals; Basophils; beta-N-Acetylhexosaminidases; CD24 Antigen; Chemokine CCL2; Chemokine CXCL2; Dietary Supplements; Dinitrophenols; Dose-Response Relationship, Drug; Edema; Histamine; Histamine Release; Immunoglobulin E; Inflammation; Intracellular Signaling Peptides and Proteins; Male; Mast Cells; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Phospholipase C gamma; Phosphorylation; Phytotherapy; Plant Extracts; Protein-Tyrosine Kinases; Rats; Resveratrol; Serum Albumin; Skin; Stilbenes; Syk Kinase; Vitis | 2013 |
Activation of SIRT1 by resveratrol requires lamin A.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lamin Type A; Mice; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
All-trans-retinal sensitizes human RPE cells to alternative complement pathway-induced cell death.
Topics: Angiogenesis Inhibitors; Cell Death; Cells, Cultured; Complement Pathway, Alternative; Flow Cytometry; Humans; Macular Degeneration; Male; Middle Aged; Resveratrol; Retinal Pigment Epithelium; Ribonucleotide Reductases; Stilbenes | 2013 |
Exploring the promise of resveratrol: where do we go from here?
Topics: Antioxidants; Body Composition; Humans; Insulin Resistance; Male; Obesity; Resveratrol; Stilbenes | 2013 |
Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; Checkpoint Kinase 2; Cyclin B; Dacarbazine; DNA Damage; Drug Synergism; G2 Phase Cell Cycle Checkpoints; Glioblastoma; Histones; Humans; Mitosis; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; Resveratrol; Stilbenes; Temozolomide; Time Factors | 2013 |
A potential role for resveratrol as a radiation sensitizer for melanoma treatment.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Cyclin D; Drug Therapy; Humans; Inhibitor of Apoptosis Proteins; Melanoma; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Radiotherapy; Resveratrol; Skin Neoplasms; Stilbenes; Survivin | 2013 |
Resveratrol protects spinal cord dorsal column from hypoxic injury by activating Nrf-2.
Topics: Animals; Antioxidants; Blotting, Western; Fluorescent Antibody Technique; Hypoxia; Immunohistochemistry; Male; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Spinal Cord; Spinal Cord Injuries; Stilbenes | 2013 |
Sirt1 activation by resveratrol is substrate sequence-selective.
Topics: Acetylation; Humans; Microarray Analysis; Resveratrol; Sirtuin 1; Stilbenes; Substrate Specificity | 2013 |
Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Chromans; Extracellular Signal-Regulated MAP Kinases; Fatty Acid-Binding Proteins; Gene Expression Regulation; Mice; Naphthalenes; PPAR gamma; Pyrones; Resveratrol; Stem Cells; Stilbenes; Thiazolidinediones; Troglitazone | 2013 |
Dynamic mobilization of PGC-1α mediates mitochondrial biogenesis for the protection of RGC-5 cells by resveratrol during serum deprivation.
Topics: Animals; Caspase 3; Cell Line; Cell Survival; Culture Media; Cytochromes c; DNA-Binding Proteins; Gene Expression Regulation; High Mobility Group Proteins; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Turnover; Niacinamide; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Transport; Resveratrol; Retinal Ganglion Cells; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
Multiple phytoestrogens inhibit cell growth and confer cytoprotection by inducing manganese superoxide dismutase expression.
Topics: Animals; Cell Cycle; Cell Line; Cell Proliferation; Coumestrol; Cytoprotection; Estradiol; Fulvestrant; Genistein; Isoflavones; Kaempferols; Mice; Myoblasts; Phytoestrogens; Receptors, Estrogen; Resveratrol; Stilbenes; Stress, Physiological; Superoxide Dismutase | 2014 |
Fatty acid ethyl esters induce intestinal epithelial barrier dysfunction via a reactive oxygen species-dependent mechanism in a three-dimensional cell culture model.
Topics: Adenosine Triphosphate; Caco-2 Cells; Cell Culture Techniques; Cell Membrane Permeability; Ethanol; Humans; Intestinal Mucosa; Models, Biological; Occludin; Oleic Acids; Oxidative Stress; Palmitic Acids; Reactive Oxygen Species; Resveratrol; Stilbenes; Tight Junctions; Zonula Occludens-1 Protein | 2013 |
A synergetic screening approach with companion effector for combination therapy: application to retinoblastoma.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Reproducibility of Results; Resveratrol; Retinal Neoplasms; Retinoblastoma; Small Molecule Libraries; Stilbenes | 2013 |
Resveratrol induces long-lasting IL-8 expression and peculiar EGFR activation/distribution in human keratinocytes: mechanisms and implications for skin administration.
Topics: Administration, Cutaneous; Blotting, Western; Cell Cycle; Cell Membrane; Cell Nucleus; Cell Proliferation; Cytoplasm; DNA Primers; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Gene Expression Regulation; Glucosides; Humans; Interleukin-8; Keratinocytes; Phenols; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Time Factors | 2013 |
Resveratrol and quercetin in combination have anticancer activity in colon cancer cells and repress oncogenic microRNA-27a.
Topics: Antineoplastic Agents, Phytogenic; Caspase 3; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Enzyme Activation; HT29 Cells; Humans; Kinetics; MicroRNAs; Quercetin; Reactive Oxygen Species; Resveratrol; Sp1 Transcription Factor; Sp3 Transcription Factor; Sp4 Transcription Factor; Stilbenes | 2013 |
Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.
Topics: Blotting, Western; Cell Line, Tumor; Cellular Senescence; DNA Damage; Flow Cytometry; Humans; Lung Neoplasms; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2013 |
Enhanced neuroprotective effects of resveratrol delivered by nanoparticles on hydrogen peroxide-induced oxidative stress in rat cortical cell culture.
Topics: Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Drug Delivery Systems; Hydrogen Peroxide; Nanoparticles; Neurons; Neuroprotective Agents; Oxidative Stress; Polyesters; Povidone; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits proliferation, angiogenesis and induces apoptosis in colon cancer cells: calorie restriction is the force to the cytotoxicity.
Topics: Antineoplastic Agents; Apoptosis; Caco-2 Cells; Caloric Restriction; Cell Proliferation; Citrate (si)-Synthase; Glucose; HCT116 Cells; Humans; L-Lactate Dehydrogenase; Leptin; Neovascularization, Physiologic; Proto-Oncogene Proteins c-myc; Pyruvate Kinase; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Regression of endometrial implants by resveratrol in an experimentally induced endometriosis model in rats.
Topics: Animals; Disease Models, Animal; Endometriosis; Endometrium; Female; Random Allocation; Rats; Rats, Sprague-Dawley; Remission Induction; Resveratrol; Stilbenes | 2013 |
Resveratrol up-regulates the erythrocyte plasma membrane redox system and mitigates oxidation-induced alterations in erythrocytes during aging in humans.
Topics: Aging; Antioxidants; Erythrocyte Membrane; Humans; Oxidation-Reduction; Resveratrol; Stilbenes; Up-Regulation | 2013 |
The antioxidant resveratrol down-regulates inflammation in an in-vitro model of Pseudomonas aeruginosa infection of lung epithelial cells.
Topics: Antioxidants; Cell Line; Down-Regulation; Epithelial Cells; Humans; Inflammation; Lung; Pseudomonas aeruginosa; Pseudomonas Infections; Reactive Oxygen Species; Respiratory Mucosa; Resveratrol; Stilbenes | 2013 |
Effects of resveratrol on changes induced by high-fat feeding on clock genes in rats.
Topics: Adipose Tissue; Animals; Antioxidants; Body Weight; Circadian Rhythm; CLOCK Proteins; Diet, High-Fat; Down-Regulation; Fatty Acid Synthases; Gene Expression Profiling; Gene Expression Regulation; Lipogenesis; Liver; Male; Nuclear Receptor Subfamily 1, Group D, Member 1; Rats; Rats, Wistar; Resveratrol; Stilbenes; Suprachiasmatic Nucleus | 2013 |
Reversed phase High Performance Liquid Chromatography used for the physicochemical and thermodynamic characterization of piceatannol/β-cyclodextrin complex.
Topics: beta-Cyclodextrins; Chromatography, High Pressure Liquid; Resveratrol; Stilbenes; Thermodynamics | 2013 |
Epigallocatechin-3-gallate is a potent phytochemical inhibitor of intimal hyperplasia in the wire-injured carotid artery.
Topics: Animals; Cardiovascular Agents; Carotid Artery Injuries; Carotid Artery, Common; Carotid Intima-Media Thickness; Catechin; Cell Proliferation; Disease Models, Animal; Disulfides; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hyperplasia; Injections, Intraperitoneal; Isothiocyanates; Male; Neointima; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfinic Acids; Sulfoxides; Time Factors | 2013 |
Resveratrol is cidal to both classes of Haemophilus ducreyi.
Topics: Anti-Bacterial Agents; Haemophilus ducreyi; Humans; Lactobacillus; Microbial Viability; Resveratrol; Stilbenes | 2013 |
Resveratrol-induced apoptosis is enhanced by inhibition of autophagy in esophageal squamous cell carcinoma.
Topics: Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Line, Tumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; K562 Cells; Microscopy, Electron, Transmission; Resveratrol; Stilbenes | 2013 |
Attenuation of arsenic retention by resveratrol in lung of arsenic trioxide-exposed rats.
Topics: Animals; Antioxidants; Arsenic; Arsenic Trioxide; Arsenicals; Environmental Pollutants; Glutathione; Lung; Male; Oxidative Stress; Oxides; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol suppresses microcirculatory disturbance in a rat model of severe acute pancreatitis.
Topics: Acute Disease; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Endothelins; Microcirculation; Nitric Oxide; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Renin; Resveratrol; Stilbenes; Taurocholic Acid | 2013 |
Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets.
Topics: Animals; Apoptosis; Axons; Brain-Derived Neurotrophic Factor; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; NAD; Neurons; Neuroprotective Agents; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes | 2013 |
Cardioprotective effect of resveratrol and resveratroloside.
Topics: Animals; Cardiotonic Agents; Dose-Response Relationship, Drug; Glucosides; Infusions, Parenteral; Male; Myocardial Infarction; Rats; Rats, Wistar; Reference Standards; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.
Topics: Amino Acid Sequence; Catalytic Domain; Cloning, Molecular; Cyclic AMP; Cyclic GMP; Humans; Nuclear Proteins; Protein Conformation; Resveratrol; Sequence Deletion; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
SIRT1 and Connexin40 Mediate the normal shear stress-induced inhibition of the proliferation of endothelial cells co-cultured with vascular smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Coculture Techniques; Connexins; Endothelial Cells; Enzyme Inhibitors; Flow Cytometry; Gap Junction alpha-5 Protein; Male; Muscle, Smooth, Vascular; Naphthols; Phenylpropionates; Rats; Rats, Sprague-Dawley; Resveratrol; RNA Interference; RNA, Small Interfering; Shear Strength; Sirtuin 1; Stilbenes | 2013 |
Resveratrol and fish oil reduce catecholamine-induced mortality in obese rats: role of oxidative stress in the myocardium and aorta.
Topics: Animals; Antioxidants; Aorta; Catecholamines; Dietary Fats; Dietary Supplements; Fish Oils; Isoproterenol; Male; Microfilament Proteins; Myocardium; NF-E2-Related Factor 2; Obesity; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits β-amyloid-induced neuronal apoptosis through regulation of SIRT1-ROCK1 signaling pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Calcium; Cell Survival; Flow Cytometry; Gene Expression Regulation; Homeostasis; L-Lactate Dehydrogenase; Neurodegenerative Diseases; Neurons; PC12 Cells; Peptide Fragments; Rats; Resveratrol; rho-Associated Kinases; Signal Transduction; Sirtuin 1; Stilbenes; Tetrazolium Salts; Thiazoles | 2013 |
Resveratrol inhibits the deleterious effects of diet-induced obesity on thymic function.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Body Weight; Carnitine O-Palmitoyltransferase; Diet, High-Fat; Dose-Response Relationship, Drug; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Size; Resveratrol; Stilbenes; T-Lymphocytes; Thymus Gland | 2013 |
The immunomodulation effect of Aronia extract lacks association with its antioxidant anthocyanins.
Topics: Anthocyanins; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Ferric Compounds; Fruit; Humans; Immunologic Factors; Interleukin-10; Lipopolysaccharides; Monocytes; Photinia; Picrates; Plant Extracts; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Biotransformation of polydatin to resveratrol in Polygonum cuspidatum roots by highly immobilized edible Aspergillus niger and Yeast.
Topics: Aspergillus niger; Biotransformation; Cells, Immobilized; Fallopia japonica; Glucosides; Plant Roots; Recycling; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2013 |
Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors.
Topics: Acetylation; Biological Products; Cells, Cultured; E1A-Associated p300 Protein; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Monocytes; Optical Imaging; Peptide Fragments; Resveratrol; Sirtuin 1; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes | 2013 |
trans-Resveratrol and ε-viniferin decrease glucose absorption in porcine jejunum and ileum in vitro.
Topics: Animals; Benzofurans; Biological Transport, Active; Glucose; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Resveratrol; Sodium-Glucose Transporter 1; Stilbenes; Swine | 2013 |
3,5,4'-tri-O-acetylresveratrol ameliorates seawater exposure-induced lung injury by upregulating connexin 43 expression in lung.
Topics: Acute Lung Injury; Animals; Blotting, Western; Cell Line; Connexin 43; Humans; Interleukin-10; Interleukin-1beta; Lung; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Seawater; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Induction of stilbene phytoalexins in grapevine (Vitis vinifera) and transgenic stilbene synthase-apple plants (Malus domestica) by a culture filtrate of Aureobasidium pullulans.
Topics: Acyltransferases; Ascomycota; Gene Expression Regulation, Plant; Malus; Phytoalexins; Plants, Genetically Modified; Resveratrol; Sesquiterpenes; Stilbenes; Vitis | 2013 |
Exploiting the role of resveratrol in rat mitochondrial permeability transition.
Topics: Animals; Anticarcinogenic Agents; Membrane Fluidity; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membranes; Oxygen Consumption; Permeability; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol.
Topics: Analysis of Variance; Cell Line; Forkhead Transcription Factors; Gene Knockdown Techniques; Humans; Nitric Oxide Synthase Type III; Promoter Regions, Genetic; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Transcriptional Activation; Up-Regulation | 2013 |
Enhanced physical and oxidative stabilities of soy protein-based emulsions by incorporation of a water-soluble stevioside-resveratrol complex.
Topics: Antioxidants; Diterpenes, Kaurane; Emulsions; Glucosides; Hydrophobic and Hydrophilic Interactions; Lipid Peroxides; Micelles; Oxidation-Reduction; Particle Size; Resveratrol; Solubility; Soybean Proteins; Spectrometry, Fluorescence; Stilbenes; Water | 2013 |
Evaluation of longevity enhancing compounds against transactive response DNA-binding protein-43 neuronal toxicity.
Topics: Aging; Animals; Caenorhabditis elegans; Chromans; DNA-Binding Proteins; Ethosuximide; Longevity; Motor Neurons; Neuroprotective Agents; Propyl Gallate; Reserpine; Resveratrol; Rolipram; Stilbenes | 2013 |
Resveratrol reduces matrix metalloproteinase-2 activity induced by oxygen-glucose deprivation and reoxygenation in human cerebral microvascular endothelial cells.
Topics: Antioxidants; Brain; Brain Ischemia; Cell Line; Endothelial Cells; Enzyme Precursors; Gelatinases; Glucose; Humans; L-Lactate Dehydrogenase; Matrix Metalloproteinase 2; Microcirculation; Neuroprotective Agents; Oxygen; Reactive Oxygen Species; Reperfusion; Resveratrol; Stilbenes | 2012 |
Resveratrol suppresses T0901317-induced hepatic fat accumulation in mice.
Topics: Animals; Cells, Cultured; Fatty Liver; Hepatocytes; Hydrocarbons, Fluorinated; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Orphan Nuclear Receptors; Resveratrol; Stilbenes; Sulfonamides | 2013 |
Resveratrol confers protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Astrocytes; Down-Regulation; Female; Microglia; Neuroglia; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Peroxidase; Pregnancy; Rats, Sprague-Dawley; Resveratrol; Rotenone; Stilbenes | 2013 |
Two-dimensional evaluations for mitochondrial number are not reliable. Re: 'neurodegeneration in streptozotocin-induced diabetic rats is attenuated by treatment with resveratrol' by Jing et al.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Male; Nerve Degeneration; Resveratrol; Stilbenes | 2013 |
Resveratrol induces differentiation markers expression in anaplastic thyroid carcinoma via activation of Notch1 signaling and suppresses cell growth.
Topics: Animals; Anticarcinogenic Agents; Antigens, Differentiation; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Humans; Male; Mice; Random Allocation; Receptor, Notch1; Resveratrol; Signal Transduction; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Xenograft Model Antitumor Assays | 2013 |
Biological characterization of oxidized hyaluronic acid/resveratrol hydrogel for cartilage tissue engineering.
Topics: Animals; Cartilage; Chondrocytes; Cross-Linking Reagents; Gene Expression Regulation; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Mice; Mice, Inbred ICR; Microscopy, Electron, Scanning; Oxidation-Reduction; Resveratrol; RNA, Messenger; Spectroscopy, Fourier Transform Infrared; Stilbenes; Tissue Engineering | 2013 |
Resveratrol has anti-leukemic activity associated with decreased O-GlcNAcylated proteins.
Topics: 3T3 Cells; Acetylglucosamine; Animals; Drug Antagonism; Humans; Interferons; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Proteins; Resveratrol; Stilbenes | 2013 |
[Research on regulation of cell senescence by miRNA-34a].
Topics: Cellular Senescence; Down-Regulation; HEK293 Cells; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Transfection | 2013 |
Influence of resveratrol on oxidative stress resistance and life span in Caenorhabditis elegans.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Glucose; Longevity; Naphthoquinones; Oxidative Stress; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2013 |
Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Blotting, Western; Brain Ischemia; Cells, Cultured; Cytidine Diphosphate Choline; Drug Synergism; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Knockout; Monocytes; Naphthols; Neurons; Neuroprotective Agents; Nootropic Agents; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Stilbenes; Stroke | 2013 |
Resveratrol induces cell death in cervical cancer cells through apoptosis and autophagy.
Topics: Anticarcinogenic Agents; Apoptosis; Autophagy; Blotting, Western; Cell Cycle; Cell Proliferation; Female; Humans; Membrane Potential, Mitochondrial; NF-kappa B; Papillomaviridae; Papillomavirus Infections; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2013 |
Resveratrol protects against physical fatigue and improves exercise performance in mice.
Topics: Ammonia; Animals; Antioxidants; Blood Glucose; Body Weight; Creatine Kinase; Dietary Supplements; Fatigue; Glycogen; Kidney; Lactic Acid; Liver; Male; Mice; Muscle, Skeletal; Physical Conditioning, Animal; Resveratrol; Stilbenes; Swimming | 2013 |
Influence of processing on pharmacokinetic of typical constituents in radix polygoni multiflori after oral administration by LC-ESI-MS/MS.
Topics: Animals; Chromatography, Liquid; Drugs, Chinese Herbal; Emodin; Gallic Acid; Glucosides; Male; Medicine, Chinese Traditional; Models, Biological; Plant Roots; Polygonum; Rats; Rats, Sprague-Dawley; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2013 |
Ebselen analogues reduce 2-chloroethyl ethyl sulphide toxicity in A-431 cells.
Topics: Antioxidants; Azoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemical Warfare Agents; Humans; Isoindoles; Mustard Gas; Organoselenium Compounds; Oxidative Stress; Protective Agents; Resveratrol; Stilbenes | 2013 |
Cerebroprotective effect of resveratrol through antioxidant and anti-inflammatory effects in diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Catalase; Cerebral Infarction; Cytokines; Diabetes Mellitus, Experimental; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Resolution of the direct interaction with and inhibition of the human GLUT1 hexose transporter by resveratrol from its effect on glucose accumulation.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glucose Transporter Type 1; HL-60 Cells; Humans; Resveratrol; Stilbenes; U937 Cells | 2013 |
Simultaneous determination of dihydromyricetin and resveratrol in Ampelopsis sinica (Miq.) W.T. Wang by high-performance liquid chromatography coupled with a diode array detection method.
Topics: Ampelopsis; Chromatography, High Pressure Liquid; Drug Stability; Drugs, Chinese Herbal; Flavonols; Limit of Detection; Linear Models; Reproducibility of Results; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2014 |
Resveratrol diminishes platelet aggregation and increases susceptibility of K562 tumor cells to natural killer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Communication; Dose-Response Relationship, Drug; Humans; K562 Cells; Killer Cells, Natural; Neoplasms, Experimental; Platelet Aggregation; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Effect of resveratrol on cultured skin fibroblasts from patients with oxidative phosphorylation defects.
Topics: Cells, Cultured; Citrate (si)-Synthase; Cytochrome-c Oxidase Deficiency; Electron Transport Complex II; Electron Transport Complex IV; Fibroblasts; Humans; Mitochondria; Oxidative Phosphorylation; Resveratrol; Stilbenes | 2014 |
Resveratrol-loaded lipid-core nanocapsules treatment reduces in vitro and in vivo glioma growth.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemical Phenomena; Chemistry, Pharmaceutical; Disease Models, Animal; G1 Phase; Glioma; Hippocampus; Humans; Lipids; Male; Nanocapsules; Neoplasm Transplantation; Rats; Rats, Wistar; Resveratrol; S Phase; Solutions; Stilbenes; Tumor Burden | 2013 |
Development of a reagentless electrochemiluminescent electrode for flow injection analysis using copolymerised luminol/aniline on nano-TiO2 functionalised indium-tin oxide glass.
Topics: Aniline Compounds; Antioxidants; Electrochemical Techniques; Electrochemistry; Electrodes; Flow Injection Analysis; Glass; Indium; Luminescence; Luminol; Microscopy, Electron, Scanning; Molecular Structure; Polymers; Reactive Oxygen Species; Reproducibility of Results; Resveratrol; Stilbenes; Tin Compounds; Titanium; Wine | 2013 |
Does resveratrol improve insulin signaling in chronically ischemic myocardium?
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Glucose; Insulin; Male; Metabolic Syndrome; Myocardial Ischemia; Myocardium; Resveratrol; Signal Transduction; Stilbenes; Swine | 2013 |
Inhibition of VEGF expression in cancer cells and endothelial cell differentiation by synthetic stilbene derivatives.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Aorta; Cattle; Cell Line, Tumor; Cell Proliferation; Endothelial Cells; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
Resveratrol reduces acute lung injury in a LPS‑induced sepsis mouse model via activation of Sirt1.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Disease Models, Animal; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Matrix Metalloproteinase 9; Mice; Nitric Oxide Synthase Type II; Resveratrol; RNA Interference; RNA, Small Interfering; Sepsis; Sirtuin 1; Stilbenes; Up-Regulation | 2013 |
Resveratrols in grape berry skins and leaves in vitis germplasm.
Topics: Chromatography, High Pressure Liquid; Fruit; Plant Extracts; Plant Leaves; Principal Component Analysis; Resveratrol; Stilbenes; Vitis | 2013 |
Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis.
Topics: Antidotes; Antioxidants; Apoptosis; Ascorbic Acid; Azoles; Caspase 3; Caspase 9; Cell Line; Chemical Warfare Agents; Cytoprotection; Humans; Irritants; Isoindoles; Mechlorethamine; Organoselenium Compounds; Resveratrol; Stilbenes | 2013 |
Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest.
Topics: Adenosine A3 Receptor Antagonists; AMP-Activated Protein Kinases; Apoptosis; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclin D1; G1 Phase Cell Cycle Checkpoints; Glucuronides; Hemolysis; Humans; Receptor, Adenosine A3; Resveratrol; Stilbenes | 2013 |
Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells.
Topics: Animals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Gene Silencing; Glioma; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred BALB C; Nanog Homeobox Protein; Neoplastic Stem Cells; Proteasome Endopeptidase Complex; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Transfection; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction.
Topics: Animals; Antioxidants; Cell Cycle Proteins; Diet, High-Fat; Gene Knockdown Techniques; Heat-Shock Proteins; Hep G2 Cells; Humans; Hydrocarbons, Fluorinated; Lipogenesis; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Nuclear Proteins; Orphan Nuclear Receptors; Peroxidases; Proteins; Resveratrol; RNA, Small Interfering; Sterol Regulatory Element Binding Protein 1; Stilbenes; Sulfonamides; Up-Regulation | 2013 |
Trimethoxy-resveratrol and piceatannol administered orally suppress and inhibit tumor formation and growth in prostate cancer xenografts.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Growth Inhibitors; Male; Mice; Mice, Nude; Prostatic Neoplasms; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2013 |
[Study of apoptosis related factors regulatory mechanism of resveratrol to human skin squamous cell carcinoma A431 xenograft in nude mice].
Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Nude; Resveratrol; Skin Neoplasms; Stilbenes; Survivin; Xenograft Model Antitumor Assays | 2013 |
Inhibitory effects of resveratrol on MCP-1, IL-6, and IL-8 production in human coronary artery smooth muscle cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Coronary Vessels; Cytokines; Extracellular Signal-Regulated MAP Kinases; Humans; Myocytes, Smooth Muscle; Resveratrol; Stilbenes | 2013 |
Resveratrol role in Staphylococcus aureus-induced corneal inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Disease Models, Animal; Gene Expression Profiling; Immunohistochemistry; Interleukin-8; Keratitis; Rabbits; Real-Time Polymerase Chain Reaction; Resveratrol; Staphylococcal Infections; Stilbenes; Toll-Like Receptor 2; Treatment Outcome | 2013 |
Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol.
Topics: Anticarcinogenic Agents; Base Sequence; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Primers; Fluorescent Antibody Technique; Gene Knockdown Techniques; Humans; Imidazoles; Molecular Sequence Data; Phosphoprotein Phosphatases; Piperazines; Point Mutation; Protein Phosphatase 2C; Proto-Oncogene Proteins c-mdm2; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Stilbenes; Tumor Suppressor Protein p53 | 2013 |
Effects of resveratrol in pregnancy using murine models with reduced blood supply to the uterus.
Topics: Analysis of Variance; Animals; Blood Flow Velocity; Blood Pressure; Catechol O-Methyltransferase; Female; Fetal Growth Retardation; Fetal Weight; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Acoustic; Nitric Oxide Synthase Type III; Pre-Eclampsia; Pregnancy; Proteinuria; Regional Blood Flow; Resveratrol; Stilbenes; Uterus | 2013 |
Polyphenols protect the epithelial barrier function of Caco-2 cells exposed to indomethacin through the modulation of occludin and zonula occludens-1 expression.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caco-2 Cells; Catechin; Enterocytes; Functional Food; Gene Expression Regulation; Humans; Indomethacin; Occludin; Permeability; Polyphenols; Protein Transport; Quercetin; Resveratrol; Stilbenes; Tight Junctions; Zonula Occludens-1 Protein | 2013 |
In vitro effects of resveratrol on oxidative stress in diabetic platelets.
Topics: Adult; Aged; Antioxidants; Blood Platelets; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Male; Membrane Fluidity; Middle Aged; Oxidative Stress; Resveratrol; Stilbenes | 2014 |
Chronic resveratrol administration improves diabetic cardiomyopathy in part by reducing oxidative stress.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dose-Response Relationship, Drug; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2014 |
In vitro and in vivo evaluation of the antitumor efficiency of resveratrol against lung cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Cell Proliferation; Female; Humans; In Vitro Techniques; Lung Neoplasms; Male; Mice; Mice, Nude; Resveratrol; Stilbenes; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2013 |
Autophagic cell death induced by resveratrol depends on the Ca(2+)/AMPK/mTOR pathway in A549 cells.
Topics: Adenylate Kinase; Autophagy; Base Sequence; Calcium; Cell Death; Cell Line, Tumor; Humans; Phosphorylation; Polymerase Chain Reaction; Resveratrol; RNA, Small Interfering; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells.
Topics: Acetylation; Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; GADD45 Proteins; Heterocyclic Compounds, 4 or More Rings; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Indoles; Intracellular Signaling Peptides and Proteins; Lymphoma; NF-kappa B; Panobinostat; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-myc; Resveratrol; RNA Interference; RNA, Small Interfering; Sirtuin 1; STAT3 Transcription Factor; Stilbenes; Up-Regulation | 2013 |
Trans-resveratrol loaded chitosan nanoparticles modified with biotin and avidin to target hepatic carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Avidin; Biotin; Cell Survival; Chitosan; Drug Delivery Systems; Female; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Mice; Nanoparticles; Resveratrol; Stilbenes | 2013 |
Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway.
Topics: Aging; Animals; Cyclic AMP Response Element-Binding Protein; Hippocampus; Learning; Memory; Mice; Mice, Inbred C57BL; MicroRNAs; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Resveratrol supplementation preserves long bone mass, microstructure, and strength in hindlimb-suspended old male rats.
Topics: Aging; Animals; Biomarkers; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Remodeling; C-Reactive Protein; Dietary Supplements; Female; Femur; Hindlimb Suspension; Male; Organ Size; Osteocalcin; Rats; Resveratrol; Stilbenes; Tibia; Walking | 2014 |
Effects of pre- and post-treatment with plant polyphenols on human keratinocyte responses to solar UV.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Glucosides; Humans; Keratinocytes; Nitric Oxide; Peroxides; Peroxynitrous Acid; Phenols; Quercetin; Resveratrol; Stilbenes; Ultraviolet Rays | 2013 |
Differences in the methylation patterns of the VaSTS1 and VaSTS10 genes of Vitis amurensis Rupr.
Topics: Acyltransferases; Azacitidine; Cytosine; DNA Methylation; DNA, Plant; Epigenesis, Genetic; Gene Expression Regulation, Plant; Genes, Plant; Resveratrol; Stilbenes; Vitis | 2013 |
Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1.
Topics: Astrocytes; Cell Line; Glutathione; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Nitric Oxide Synthase Type II; Oxidative Stress; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Proto-oncogenic isoform A2 of eukaryotic translation elongation factor eEF1 is a target of miR-663 and miR-744.
Topics: Breast Neoplasms; Cell Growth Processes; Cell Movement; Down-Regulation; Female; Humans; MCF-7 Cells; MicroRNAs; Peptide Elongation Factor 1; Proto-Oncogene Mas; Resveratrol; RNA, Messenger; Stilbenes; Transfection | 2013 |
Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Biomarkers; Blood Pressure; Blotting, Western; Dietary Supplements; Doxorubicin; Electron Transport Chain Complex Proteins; Female; GTP Phosphohydrolases; Heart Diseases; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Physical Conditioning, Animal; Resveratrol; Stilbenes; Ventricular Dysfunction, Left | 2013 |
Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants.
Topics: Animals; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Gene Knockout Techniques; Hydrogen Peroxide; Mice; Mitochondria; Necrosis; Oxidants; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Influence of glucuronidation and reduction modifications of resveratrol on its biological activities.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Binding Sites; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Glucuronides; Hemolysis; Humans; Kinetics; Mice; Molecular Docking Simulation; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Resveratrol; Serum Albumin; Stilbenes | 2013 |
[Fluorescence microscopy and HPLC assay for rapid detection of distribution and content of resveratrol in Polygonum cuspidatum].
Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Microscopy, Fluorescence; Microwaves; Plant Leaves; Plant Stems; Quality Control; Resveratrol; Rhizome; Stilbenes | 2012 |
Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice.
Topics: Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Humans; Hypertension; Mice; Rats; Resveratrol; Stilbenes | 2013 |
A label-free electrochemiluminescence cytosensors for specific detection of early apoptosis.
Topics: Aniline Compounds; Annexin A5; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biosensing Techniques; Cadmium Compounds; Hep G2 Cells; Humans; Immobilized Proteins; Limit of Detection; Luminescent Measurements; Nanofibers; Phosphatidylserines; Quantum Dots; Resveratrol; Stilbenes; Sulfides | 2013 |
Age-associated changes in gene expression and developmental competence of bovine oocytes, and a possible countermeasure against age-associated events.
Topics: Animals; Carbazoles; Cattle; Embryo, Mammalian; Female; Fertilization; Fluorescence; Gene Expression Profiling; Gene Expression Regulation, Developmental; High-Throughput Nucleotide Sequencing; Maternal Age; Oocytes; Pregnancy; Pregnancy Outcome; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Involvement of heme oxygenase-1 expression in neuroprotection by piceatannol, a natural analog and a metabolite of resveratrol, against glutamate-mediated oxidative injury in HT22 neuronal cells.
Topics: Animals; Cell Line; Cell Survival; Cytoprotection; Glutamates; Heme Oxygenase-1; Membrane Proteins; Mice; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Resveratrol; RNA Interference; RNA, Small Interfering; Stilbenes | 2013 |
Construction of a multifunctional enzyme complex via the strain-promoted azide-alkyne cycloaddition.
Topics: Alkynes; Azides; Biocatalysis; Coenzyme A; Cyclization; Glycosylation; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes | 2013 |
Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Adiponectin; Animals; Apelin; Cell Differentiation; Gene Expression; Glucuronides; Intercellular Signaling Peptides and Proteins; Leptin; Mice; Nicotinamide Phosphoribosyltransferase; Resveratrol; RNA, Messenger; Stilbenes | 2013 |
Resveratrol derived butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
Proteomic profiling reveals that resveratrol inhibits HSP27 expression and sensitizes breast cancer cells to doxorubicin therapy.
Topics: Antineoplastic Agents; Apoptosis; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; HSP27 Heat-Shock Proteins; Humans; MCF-7 Cells; Proteome; Proteomics; Resveratrol; RNA, Small Interfering; Stilbenes; Tandem Mass Spectrometry | 2013 |
Preventive effects of resveratrol against azoxymethane induced damage in rat liver.
Topics: Animals; Antioxidants; Azoxymethane; Carcinogens; Female; Glutathione; Liver Diseases; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Dual role of resveratrol in modulation of genotoxicity induced by sodium arsenite via oxidative stress and apoptosis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Arsenites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromosome Breakage; Comet Assay; DNA Damage; Glutathione; Humans; Lung Neoplasms; Micronuclei, Chromosome-Defective; Mutagens; Neoplastic Stem Cells; Osmolar Concentration; Oxidation-Reduction; Oxidative Stress; Resveratrol; Sodium Compounds; Stilbenes | 2013 |
Semi-preparative isolation of dihydroresveratrol-3-O-β-d-glucuronide and four resveratrol conjugates from human urine after oral intake of a resveratrol-containing dietary supplement.
Topics: Administration, Oral; Adult; Chromatography, High Pressure Liquid; Dietary Supplements; Drug Stability; Female; Glucuronides; Humans; Male; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Solid Phase Extraction; Stilbenes | 2013 |
Resveratrol protects vascular endothelial cells from high glucose-induced apoptosis through inhibition of NADPH oxidase activation-driven oxidative stress.
Topics: Animals; Apoptosis; Cells, Cultured; Endothelial Cells; Enzyme Activation; Glucose; Mice; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidases; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol ameliorates subacute intestinal ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Intestine, Small; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred BALB C; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Reperfusion Injury; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
HS-1793, a recently developed resveratrol analogue protects rat heart against hypoxia/reoxygenation injury via attenuating mitochondrial damage.
Topics: Animals; Calcium; Heart; Hypoxia; Mitochondria; Myocardial Reperfusion Injury; Naphthols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resorcinols; Resveratrol; Stilbenes | 2013 |
Observation of human retinal remodeling in octogenarians with a resveratrol based nutritional supplement.
Topics: Administration, Oral; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Asian People; Bevacizumab; Biomarkers; Choroidal Neovascularization; Dietary Supplements; Female; Humans; Macular Degeneration; Male; Ranibizumab; Resveratrol; Retina; Retinal Pigment Epithelium; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Quality assessment of Japanese knotweed (Fallopia japonica) grown on Prince Edward Island as a source of resveratrol.
Topics: Antioxidants; Emodin; Fallopia japonica; Glucosides; Plant Leaves; Plant Roots; Plant Stems; Plant Weeds; Prince Edward Island; Quality Control; Resveratrol; Stilbenes | 2013 |
Calculation of melatonin and resveratrol effects on steatosis hepatis using soft computing methods.
Topics: Algorithms; Animals; Computer Systems; Fatty Liver; Humans; Image Processing, Computer-Assisted; Liver; Male; Melatonin; Neural Networks, Computer; Rats; Rats, Sprague-Dawley; Resveratrol; Software; Stilbenes; Support Vector Machine | 2013 |
Dietary supplementation with resveratrol and/or docosahexaenoic acid alters hippocampal gene expression in adult C57Bl/6 mice.
Topics: Animals; Apolipoproteins E; Dietary Supplements; Docosahexaenoic Acids; Gene Expression; Hippocampus; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Resveratrol; Signal Transduction; Stilbenes; Transcriptome | 2013 |
Short-term caloric restriction, resveratrol, or combined treatment regimens initiated in late-life alter mitochondrial protein expression profiles in a fiber-type specific manner in aged animals.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Apoptosis; Apoptosis Regulatory Proteins; Caloric Restriction; Combined Modality Therapy; Male; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Organ Size; Oxygen Consumption; Rats; Rats, Inbred F344; Resveratrol; Sarcopenia; Sirtuin 1; Stilbenes | 2013 |
Resveratrol induced neuroprotection is mediated via both estrogen receptor subtypes, ER(α) and ER(β).
Topics: Animals; Brain Ischemia; Cerebral Cortex; Estrogen Receptor alpha; Estrogen Receptor beta; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Stilbene analogs of resveratrol improve insulin resistance through activation of AMPK.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Humans; Insulin; Insulin Resistance; Mice; Obesity; Resveratrol; Stilbenes | 2013 |
Up-regulation of endothelial nitric oxide synthase (eNOS), silent mating type information regulation 2 homologue 1 (SIRT1) and autophagy-related genes by repeated treatments with resveratrol in human umbilical vein endothelial cells.
Topics: Autophagy; Cell Cycle Proteins; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Plant Extracts; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation; Wine | 2013 |
Resveratrol prevents development of eosinophilic rhinosinusitis with nasal polyps in a mouse model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Eosinophilia; Immunohistochemistry; Mice; Mice, Inbred BALB C; Nasal Polyps; Random Allocation; Real-Time Polymerase Chain Reaction; Reference Values; Resveratrol; Rhinitis; Risk Assessment; Sinusitis; Statistics, Nonparametric; Stilbenes; Treatment Outcome | 2013 |
Resveratrol improves vascular function in patients with hypertension and dyslipidemia by modulating NO metabolism.
Topics: Acetylcholine; Biopterins; Dyslipidemias; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; NF-E2-Related Factor 2; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Resveratrol; Stilbenes; Superoxide Dismutase; Vasodilation | 2013 |
Promoting myelination in an in vitro mouse model of the peripheral nervous system: the effect of wine ingredients [corrected].
Topics: Animals; Coculture Techniques; Ganglia, Spinal; Glutathione; Immunohistochemistry; Mice; Mice, Inbred C57BL; Models, Animal; Myelin Sheath; Peripheral Nerves; Rats; Resveratrol; Schwann Cells; Sirtuin 1; Sirtuin 2; Stilbenes; Wine | 2013 |
Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses.
Topics: Animals; Cytokines; Dopaminergic Neurons; Immunohistochemistry; Inflammation; Macrophage Activation; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neostriatum; Neuroglia; Neuroprotective Agents; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Substantia Nigra; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Tyrosine 3-Monooxygenase; Up-Regulation | 2014 |
Resveratrol attenuates early diabetic nephropathy by down-regulating glutathione s-transferases Mu in diabetic rats.
Topics: Animals; Diabetic Nephropathies; Down-Regulation; Glucose; Glutathione Transferase; Humans; Kidney; Male; Mesangial Cells; NF-E2-Related Factor 2; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Resveratrol modulates ATPase activity of liposome-reconstituted ABCG1.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Humans; Liposomes; Resveratrol; Stilbenes | 2013 |
The protective effects of resveratrol on Schwann cells with toxicity induced by ethanol in vitro.
Topics: Animals; Apoptosis; Base Sequence; Brain-Derived Neurotrophic Factor; Cells, Cultured; DNA Primers; Ethanol; Glial Cell Line-Derived Neurotrophic Factor; In Vitro Techniques; Nerve Growth Factor; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Schwann Cells; Stilbenes | 2013 |
Trans-3,4,5,4'-tetramethoxystilbene, a resveratrol analog, potently inhibits angiogenesis in vitro and in vivo.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Chick Embryo; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Resveratrol; Stilbenes | 2013 |
Resveratrol has anabolic effects on disc degeneration in a rabbit model.
Topics: Aggrecans; Anabolic Agents; Animals; Disease Models, Animal; Drug Administration Schedule; Intervertebral Disc Degeneration; Magnetic Resonance Imaging; Matrix Metalloproteinase 13; Rabbits; Radiography; Resveratrol; RNA, Messenger; Spine; Stilbenes | 2013 |
Acetal derivatives as prodrugs of resveratrol.
Topics: Molecular Structure; Prodrugs; Resveratrol; Stilbenes | 2013 |
Inhibitory effect of resveratrol against duck enteritis virus in vitro.
Topics: Animals; Antiviral Agents; Cells, Cultured; Coronavirus; Ducks; Fluorescent Antibody Technique, Indirect; Resveratrol; Stilbenes | 2013 |
A new stilbene dimer from Vitis amurensis.
Topics: Benzofurans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Stilbenes; Vitis | 2013 |
New resveratrol oligomer derivatives from the roots of Rheum lhasaense.
Topics: Antioxidants; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Extracts; Plant Roots; Resveratrol; Rheum; Stereoisomerism; Stilbenes | 2013 |
Reduced hemodynamic load aids low-dose resveratrol in reversing cardiovascular defects in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemodynamics; Hydralazine; Hypertension; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Resveratrol; Stilbenes | 2013 |
Can resveratrol in wine protect against the carcinogenicity of ethanol? A probabilistic dose-response assessment.
Topics: Animals; Antioxidants; Carcinogens; Ethanol; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Monte Carlo Method; Neoplasms; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wine | 2014 |
Resveratrol exhibits differential protective effects on fast- and slow-twitch muscles in streptozotocin-induced diabetic rats.
Topics: Acetyl-CoA Carboxylase; Animals; Antioxidants; Blood Glucose; Blotting, Western; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3; Insulin; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Long-Evans; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase; Superoxides; Triglycerides | 2014 |
Binding of resveratrol with sodium caseinate in aqueous solutions.
Topics: Caseins; Kinetics; Resveratrol; Stilbenes; Temperature; Thermodynamics | 2013 |
Thermogenesis is involved in the body-fat lowering effects of resveratrol in rats.
Topics: Adipose Tissue, Brown; Animals; Electron Transport Complex IV; Gene Expression Regulation; Humans; Male; Muscle, Skeletal; Obesity; PPAR alpha; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Thermogenesis | 2013 |
Inhibitory effect of resveratrol dimerized derivatives on nitric oxide production in lipopolysaccharide-induced RAW 264.7 cells.
Topics: Animals; Cell Line; Dimerization; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; Structure-Activity Relationship | 2013 |
The effect of resveratrol on neurodegeneration and blood brain barrier stability surrounding intracortical microelectrodes.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Electrodes, Implanted; Male; Microelectrodes; Neurons; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol, an activator of SIRT1, restores erectile function in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Down-Regulation; Erectile Dysfunction; Forkhead Box Protein O3; Forkhead Transcription Factors; Male; Penile Erection; Penis; Rats; Resveratrol; Sirtuin 1; Stilbenes; Streptozocin; Tumor Suppressor Protein p53 | 2013 |
Dual effects of resveratrol on arterial damage induced by insulin resistance in aged mice.
Topics: Aging; Animals; Antioxidants; Aorta; Blood Glucose; Chemokine CCL5; Chemokine CXCL1; Dietary Proteins; Disease Models, Animal; Insulin Resistance; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Nutritional Status; Oxidative Stress; Phenols; Resistin; Resveratrol; Ribonucleotide Reductases; Serum Albumin; Stilbenes; Superoxides; Tumor Necrosis Factor-alpha; Vascular Capacitance; Vascular Diseases; Vasodilation | 2014 |
Resveratrol repressed viability of U251 cells by miR-21 inhibiting of NF-κB pathway.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Resveratrol induces pro-oxidant effects and time-dependent resistance to cytotoxicity in activated hepatic stellate cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Cell Line; Cell Survival; Hepatic Stellate Cells; Lipid Peroxidation; Mice; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Time Factors | 2014 |
Resveratrol attenuates radiation-induced salivary gland dysfunction in mice.
Topics: Animals; Antioxidants; Male; Mice; Radiation Injuries; Resveratrol; Salivary Gland Diseases; Stilbenes | 2013 |
Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Cholinesterase Inhibitors; Clioquinol; Drug Design; Humans; Mice; Monoamine Oxidase Inhibitors; Peptide Fragments; Resveratrol; Stilbenes | 2013 |
Resveratrol induces autophagy through death-associated protein kinase 1 (DAPK1) in human dermal fibroblasts under normal culture conditions.
Topics: AMP-Activated Protein Kinases; Autophagy; Cell Culture Techniques; Death-Associated Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Lysosomes; Microtubule-Associated Proteins; Phosphorylation; Polymerase Chain Reaction; Resveratrol; RNA, Small Interfering; Skin; Stilbenes; Time Factors | 2013 |
Resveratrol inhibits K(v)2.2 currents through the estrogen receptor GPR30-mediated PKC pathway.
Topics: Action Potentials; Animals; Antioxidants; Cerebral Cortex; Female; Gene Expression Regulation; HEK293 Cells; Humans; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, G-Protein-Coupled; Resveratrol; RNA, Small Interfering; Shab Potassium Channels; Signal Transduction; Stilbenes; Tetradecanoylphorbol Acetate | 2013 |
A new resveratrol trimer from the roots and stems of Vitis wenchowensis.
Topics: Antioxidants; Biphenyl Compounds; Drug Discovery; Free Radical Scavengers; Picrates; Plant Extracts; Plant Roots; Plant Stems; Resveratrol; Stilbenes; Vitis | 2013 |
Interaction between whole buttermilk and resveratrol.
Topics: Caseins; Cultured Milk Products; Drug Carriers; Milk Proteins; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thermodynamics; Ultracentrifugation | 2013 |
Resveratrol and grape juice differentially ameliorate cardiovascular autonomic modulation in L-NAME-treated rats.
Topics: Animals; Autonomic Nervous System; Beverages; Cardiovascular System; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Oxidation-Reduction; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vasodilator Agents; Vitis | 2013 |
Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Benzhydryl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Estradiol; Estrogen Receptor alpha; Estrogens, Non-Steroidal; Female; Gene Expression Regulation, Neoplastic; Humans; Insulin Receptor Substrate Proteins; Neoplasm Proteins; Ovarian Neoplasms; Phenols; Phosphorylation; Phytoestrogens; Protein Processing, Post-Translational; Receptor, IGF Type 1; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Impact of manganese neurotoxicity on MMP-9 production and superoxide dismutase activity in rat primary astrocytes. Effect of resveratrol and therapeutical implications for the treatment of CNS diseases.
Topics: Acetylcysteine; Animals; Astrocytes; Cells, Cultured; Central Nervous System Diseases; Extracellular Signal-Regulated MAP Kinases; Manganese; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Quercetin; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Resveratrol inhibits 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose microsomes.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 3T3 Cells; Adipocytes; Adipose Tissue; Animals; Anti-Obesity Agents; Down-Regulation; Kinetics; Male; Mice; Microsomes; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Methionine adenosyltransferase 2B, HuR, and sirtuin 1 protein cross-talk impacts on the effect of resveratrol on apoptosis and growth in liver cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; ELAV Proteins; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Liver Neoplasms; Methionine Adenosyltransferase; Neoplasm Proteins; Resveratrol; RNA Stability; RNA, Messenger; RNA, Neoplasm; Sirtuin 1; Stilbenes | 2013 |
Influences of histone deacetylase inhibitors and resveratrol on DNA repair and chromatin compaction.
Topics: Animals; Butyrates; Carbazoles; CHO Cells; Chromatin; Cricetulus; Deoxyribonuclease I; DNA Breaks, Single-Stranded; DNA Repair; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Pyrimidine Dimers; Resveratrol; Stilbenes; Ultraviolet Rays | 2013 |
Synthesis and radical scavenging activities of resveratrol analogs.
Topics: Animals; Biphenyl Compounds; Cell Survival; Free Radical Scavengers; Mice; Molecular Structure; NIH 3T3 Cells; Picrates; Resveratrol; Stilbenes; Structure-Activity Relationship | 2013 |
Resveratrol suppresses PAI-1 gene expression in a human in vitro model of inflamed adipose tissue.
Topics: Adipocytes; Adipose Tissue; AMP-Activated Protein Kinases; Animals; Arrhythmias, Cardiac; Culture Media, Conditioned; DNA; Down-Regulation; Female; Gene Expression Regulation; Genetic Diseases, X-Linked; Gigantism; Heart Defects, Congenital; Humans; Inflammation; Intellectual Disability; Mice; Models, Biological; NF-E2-Related Factor 2; NF-kappa B; Phosphatidylinositol 3-Kinases; Plasminogen Activator Inhibitor 1; Protein Binding; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Time Factors; Up-Regulation | 2013 |
Inhibition of Pseudomonas aeruginosa and Escherichia coli O157:H7 biofilm formation by plant metabolite ε-viniferin.
Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Carex Plant; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Escherichia coli O157; Plant Extracts; Plants, Medicinal; Pseudomonas aeruginosa; Resveratrol; Stilbenes | 2013 |
Sub-acute toxicity profile of a modified resveratrol supplement.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cardiotonic Agents; Coumaric Acids; Dietary Supplements; Female; Male; No-Observed-Adverse-Effect Level; Phytic Acid; Quercetin; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Toxicity Tests, Subacute | 2013 |
Resveratrol supplementation improves white adipose tissue function in a depot-specific manner in Zucker diabetic fatty rats.
Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Diabetes Mellitus; Dietary Supplements; Male; Obesity; Rats; Rats, Zucker; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
[Anti-radiation effect of resveratrol].
Topics: Animals; Cobalt Radioisotopes; Gamma Rays; Mice; Plant Extracts; Radiation Injuries, Experimental; Radiation-Protective Agents; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.
Topics: AMP-Activated Protein Kinases; Antioxidants; Apoferritins; Enzyme Activation; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Jurkat Cells; K562 Cells; Leukocytes, Mononuclear; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Response Elements; Resveratrol; RNA Interference; Serine; Stilbenes; T-Lymphocytes | 2013 |
Enhanced resveratrol production in Vitis vinifera cell suspension cultures by heavy metals without loss of cell viability.
Topics: Anthocyanins; Antioxidants; Cell Culture Techniques; Cell Survival; Hydrogen-Ion Concentration; Hydroxybenzoates; Metals, Heavy; Peroxidase; Resveratrol; Stilbenes; Suspensions; Vitis | 2013 |
Time-resolved emission spectra of 4-dimethylamino-4'-cyano-stilbene and resveratrol in high viscosity solvents and silica matrices.
Topics: Nitriles; Propylene Glycol; Resveratrol; Silica Gel; Solvents; Spectrometry, Fluorescence; Stilbenes; Time Factors; Viscosity | 2013 |
M2 Kupffer cells promote M1 Kupffer cell apoptosis: a protective mechanism against alcoholic and nonalcoholic fatty liver disease.
Topics: Adult; Animals; Apoptosis; Arginase; Biomarkers; Diet, High-Fat; Enzyme Activation; Ethanol; Fatty Liver; Female; Humans; Interleukin-10; Kupffer Cells; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Obesity, Morbid; Paracrine Communication; Resveratrol; Stilbenes | 2014 |
Monitoring caffeine and resveratrol cutaneous permeation by confocal Raman microspectroscopy.
Topics: Caffeine; Humans; Microscopy, Confocal; Permeability; Resveratrol; Skin; Spectrum Analysis, Raman; Stilbenes | 2014 |
Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Proliferation; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Glucaric Acid; Humans; Interleukin-6; Mice; Mice, Inbred SENCAR; Phytochemicals; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2013 |
Nanodesign of olein vesicles for the topical delivery of the antioxidant resveratrol.
Topics: Administration, Cutaneous; Animals; Animals, Newborn; Antioxidants; Drug Carriers; Drug Compounding; Drug Design; Drug Stability; Glycerol; In Vitro Techniques; Nanoparticles; Oleic Acids; Particle Size; Resveratrol; Skin; Skin Absorption; Stilbenes; Surface Properties; Swine | 2013 |
[Effect of resveratrol on the activation of murine CD4(+);T lymphocytes].
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD4-Positive T-Lymphocytes; Immunophenotyping; Immunosuppressive Agents; Lectins, C-Type; Lymphocyte Activation; Male; Mice; Receptors, Transferrin; Resveratrol; Stilbenes | 2013 |
Nanocarriers for antioxidant resveratrol: formulation approach, vesicle self-assembly and stability evaluation.
Topics: Antioxidants; Biphenyl Compounds; Chemical Phenomena; Chemistry, Pharmaceutical; Drug Carriers; Drug Stability; Microscopy, Electron, Transmission; Nanoparticles; Picrates; Resveratrol; Stilbenes; Unilamellar Liposomes; X-Ray Diffraction | 2013 |
Aberrant regulation of the BST2 (Tetherin) promoter enhances cell proliferation and apoptosis evasion in high grade breast cancer cells.
Topics: Antigens, CD; Antineoplastic Agents, Hormonal; Apoptosis; Base Sequence; Binding Sites; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Fatty Acid-Binding Proteins; Female; Gene Expression; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Kaplan-Meier Estimate; Molecular Sequence Data; Promoter Regions, Genetic; Proportional Hazards Models; Protein Binding; Resveratrol; Stilbenes; Tamoxifen; Transforming Growth Factor beta | 2013 |
Resveratrol treatment delays growth plate fusion and improves bone growth in female rabbits.
Topics: Animals; Apoptosis; Bone Development; Cell Proliferation; Chondrocytes; Female; Femur; Growth Plate; Laminin; Ovary; Rabbits; Resveratrol; Stilbenes; Tibia; Vascular Endothelial Growth Factor A | 2013 |
Treatment with resveratrol attenuates sublesional bone loss in spinal cord-injured rats.
Topics: Animals; Bone Density; Bone Density Conservation Agents; Disease Models, Animal; Femur; Gene Expression Regulation; Inflammation Mediators; Male; Malondialdehyde; Osteoporosis; Oxidative Stress; Radiography; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Signal Transduction; Spinal Cord Injuries; Stilbenes; Sulfhydryl Compounds; Tibia | 2013 |
Resveratrol - an ingredient of red wine abrogates the reproductive capacity in male mice.
Topics: Animals; Catalase; Glutathione; Injections, Intraperitoneal; Leydig Cells; Lipid Peroxidation; Male; Mice; Oxidants; Reactive Oxygen Species; Reproduction; Resveratrol; Seminiferous Tubules; Sperm Count; Sperm Motility; Stilbenes; Superoxide Dismutase; Testis; Wine | 2014 |
Resveratrol improves postnatal hippocampal neurogenesis and brain derived neurotrophic factor in prenatally stressed rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Brain-Derived Neurotrophic Factor; Doublecortin Domain Proteins; Doublecortin Protein; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Hippocampus; Male; Microtubule-Associated Proteins; Neurogenesis; Neuropeptides; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Restraint, Physical; Resveratrol; Stilbenes | 2013 |
Individual and combined effects of CaCl₂ and UV-C on the biosynthesis of resveratrols in grape leaves and berry skins.
Topics: Acyltransferases; Calcium Chloride; Coenzyme A Ligases; Food Storage; Fruit; Gene Expression Regulation, Plant; Phenylalanine Ammonia-Lyase; Plant Leaves; Resveratrol; Stilbenes; Temperature; Trans-Cinnamate 4-Monooxygenase; Ultraviolet Rays; Vitis | 2013 |
Sirtuins as therapeutic targets of ALS.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Nucleus; Cytoplasm; Enzyme Inhibitors; Humans; Mice; Mitochondria; Resveratrol; Sirtuins; Stilbenes | 2013 |
Resveratrol stimulates sphingosine-1-phosphate signaling of cathelicidin production.
Topics: Animals; Antimicrobial Cationic Peptides; Antioxidants; Cathelicidins; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Transformed; Cyclic AMP; Endoplasmic Reticulum Stress; Epidermal Cells; Epidermis; Female; Humans; Immunity, Innate; Keratinocytes; Lysophospholipids; Mice; Mice, Hairless; NF-kappa B; Resveratrol; Signal Transduction; Sphingosine; Staphylococcal Skin Infections; Stilbenes | 2013 |
trans-Resveratrol in Gnetum gnemon protects against oxidative-stress-induced endothelial senescence.
Topics: Adult; Animals; Benzofurans; Cellular Senescence; Diabetes Mellitus, Experimental; Gnetum; Humans; Hydrogen Peroxide; Indonesia; Mice; Molecular Structure; Nitric Oxide Synthase Type III; Oxidative Stress; Resveratrol; Seeds; Sirtuin 1; Stereoisomerism; Stilbenes; Umbilical Veins | 2013 |
Calorie restriction and resveratrol supplementation prevent age-related DNA and RNA oxidative damage in a non-human primate.
Topics: Aging; Animals; Antioxidants; Basal Metabolism; Body Composition; Body Weight; Caloric Restriction; Cheirogaleidae; DNA Damage; Male; Nucleosides; Oxidation-Reduction; Oxidative Stress; Resveratrol; RNA; Seasons; Stilbenes | 2013 |
Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Resveratrol; Stilbenes; Thiazolidinediones | 2013 |
Modulation of endogenous antioxidant activity by resveratrol and exercise in mouse liver is age dependent.
Topics: Aging; Animals; Antioxidants; Disease Models, Animal; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Physical Conditioning, Animal; Resveratrol; Stilbenes | 2014 |
Short-term administration of alibernet red wine extract failed to affect blood pressure and to improve endothelial function in young normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension; Male; Peripheral Arterial Disease; Plant Extracts; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Resveratrol; Stilbenes; Treatment Failure; Treatment Outcome; Vascular Resistance; Wine | 2013 |
Density functional study of the antioxidant activity of some recently synthesized resveratrol analogues.
Topics: Antioxidants; Electron Transport; Molecular Structure; Resveratrol; Stilbenes | 2013 |
Effect of artificial ageing using different wood chips on the antioxidant activity, resveratrol and catechin concentration, sensory properties and colour of two Greek red wines.
Topics: Antioxidants; Catechin; Color; Food Handling; Humans; Pinus; Plant Extracts; Prunus; Quercus; Resveratrol; Stilbenes; Taste; Wine; Wood | 2013 |
Rapid solid-phase extraction and analysis of resveratrol and other polyphenols in red wine.
Topics: Chromatography, High Pressure Liquid; Limit of Detection; Molecular Imprinting; Polyphenols; Resveratrol; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry; Wine | 2013 |
The molecular basis for the inhibition of phosphodiesterase-4D by three natural resveratrol analogs. Isolation, molecular docking, molecular dynamics simulations, binding free energy, and bioassay.
Topics: Binding Sites; Biological Assay; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Phosphodiesterase 4 Inhibitors; Plant Extracts; Protein Binding; Protein Structure, Tertiary; Resveratrol; Stilbenes; Structure-Activity Relationship; Thermodynamics | 2013 |
Resveratrol prevents high-fructose corn syrup-induced vascular insulin resistance and dysfunction in rats.
Topics: Animals; Body Weight; Cholesterol, VLDL; Endothelin-1; Fructose; Gene Expression; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Sweetening Agents; Triglycerides | 2013 |
Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines.
Topics: Aryl Hydrocarbon Hydroxylases; Cell Death; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Pyrogallol; Resveratrol; Stilbenes; Superoxide Dismutase | 2013 |
Effects of resveratrol and SIRT1 on PGC-1α activity and mitochondrial biogenesis: a reevaluation.
Topics: Acetylation; Animals; Blotting, Western; Cell Line; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle Fibers, Skeletal; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
Piceatannol suppresses the metastatic potential of MCF10A human breast epithelial cells harboring mutated H-ras by inhibiting MMP-2 expression.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Epithelial Cells; Female; Gene Expression Regulation; Genes, ras; Humans; Matrix Metalloproteinase 2; Mutation; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Wine | 2013 |
[Restoring phenotype of dedifferentiated normal nucleus pulposus cells by resveratrol].
Topics: Adult; Aggrecans; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chondrocytes; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Intervertebral Disc; Intervertebral Disc Degeneration; Male; Phenotype; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Tissue Engineering | 2013 |
Resveratrol inhibits ionising irradiation-induced inflammation in MSCs by activating SIRT1 and limiting NLRP-3 inflammasome activation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Cells, Cultured; Humans; Inflammation; Interleukin-1beta; Mesenchymal Stem Cells; NF-kappa B; Niacinamide; NLR Family, Pyrin Domain-Containing 3 Protein; Radiation, Ionizing; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes; Up-Regulation | 2013 |
Resveratrol attenuated smokeless tobacco-induced vascular and metabolic complications in ovariectomized rats.
Topics: Animals; Aorta; Collagen; Diabetes Complications; Diabetes Mellitus; Estradiol; Female; Glucose Tolerance Test; Insulin; Metabolic Diseases; Nitrates; Nitrites; Ovariectomy; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tobacco, Smokeless; Vascular Diseases | 2013 |
The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis.
Topics: Antioxidants; Apoptosis; Arsenites; Blotting, Western; Bronchi; Cell Line; Cell Survival; DNA Damage; Epithelial Cells; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Homeostasis; Humans; Intracellular Space; Oxidative Stress; Protein Subunits; Reactive Oxygen Species; Resveratrol; Sodium Compounds; Stilbenes | 2013 |
Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.
Topics: Animals; Blood Glucose; Body Weight; Cell Dedifferentiation; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Fluorescent Antibody Technique; Glucagon; Glucagon-Like Peptide 1; Glucagon-Secreting Cells; Glucose Tolerance Test; Glycated Hemoglobin; Homeobox Protein Nkx-2.2; Homeodomain Proteins; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Macaca mulatta; Nuclear Proteins; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2013 |
Postharvest physio-pathological disorders in table grapes as affected by UV-C light.
Topics: Botrytis; Chromatography, High Pressure Liquid; Food Storage; Fruit; Plant Diseases; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2012 |
Resveratrol protects against functional impairment and cardiac structural protein degradation induced by secondhand smoke exposure.
Topics: Animals; Antioxidants; Disease Models, Animal; Male; Myocardium; Oxidative Stress; Proteins; Proteolysis; Proteomics; Recovery of Function; Resveratrol; Stilbenes; Swine; Tobacco Smoke Pollution; Vasodilator Agents; Ventricular Dysfunction; Ventricular Function | 2013 |
Resveratrol protects cardiomyocytes from oxidative stress through SIRT1 and mitochondrial biogenesis signaling pathways.
Topics: Animals; Antioxidants; Cell Line; Cell Survival; Hydrogen Peroxide; Mitochondria; Mitochondrial Turnover; Myocytes, Cardiac; NADH Dehydrogenase; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2013 |
The oxygenase CAO-1 of Neurospora crassa is a resveratrol cleavage enzyme.
Topics: Amino Acid Sequence; Molecular Sequence Data; Mutation; Neurospora crassa; Oxygenases; Phylogeny; Phytoalexins; Resveratrol; RNA, Messenger; Sesquiterpenes; Sorbose; Stilbenes | 2013 |
Resveratrol for prenatal-stress-induced oxidative damage in growing brain and its consequences on survival of neurons.
Topics: Animals; Animals, Newborn; Antioxidants; Brain; Cell Survival; Female; Hippocampus; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Restraint, Physical; Resveratrol; Stilbenes | 2014 |
Resveratrol alleviates endotoxin-induced myocardial toxicity via the Nrf2 transcription factor.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cytokines; Endotoxins; Gene Knockdown Techniques; Heart; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mitochondria; Myocytes, Cardiac; NF-E2-Related Factor 2; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Effect of resveratrol-related stilbenoids on biomembrane models.
Topics: Biological Transport; Calorimetry, Differential Scanning; Cell Membrane; Dimyristoylphosphatidylcholine; Kinetics; Models, Biological; Phospholipids; Resveratrol; Stilbenes | 2013 |
Resveratrol sensitizes tamoxifen in antiestrogen-resistant breast cancer cells with epithelial-mesenchymal transition features.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Estrogen Antagonists; Female; Humans; MCF-7 Cells; Resveratrol; Signal Transduction; Smad Proteins; Stilbenes; Tamoxifen; Transforming Growth Factor beta | 2013 |
The combination of resveratrol and conjugated linoleic acid attenuates the individual effects of these molecules on triacylglycerol metabolism in adipose tissue.
Topics: Adipose Tissue; Animals; Calcium; Drug Interactions; Fatty Acid Synthases; Gene Expression; Linoleic Acids, Conjugated; Lipase; Lipoprotein Lipase; Male; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Triglycerides | 2014 |
Mechanisms of resveratrol-induced changes in [Ca(2+)]i and cell viability in PC3 human prostate cancer cells.
Topics: Apoptosis; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Cell Survival; Homeostasis; Humans; Male; Phorbols; Prostatic Neoplasms; Protein Kinase C; Protein Kinase Inhibitors; Resveratrol; Stilbenes | 2013 |
Friend or foe? Effect of oral resveratrol on cisplatin ototoxicity.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Biopsy, Needle; Caspase 3; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Hair Cells, Auditory; Hearing Loss, Sensorineural; Immunohistochemistry; In Situ Nick-End Labeling; Male; Microscopy, Electron, Transmission; Otoacoustic Emissions, Spontaneous; Random Allocation; Rats; Rats, Wistar; Reference Values; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
The neuroprotective effect of resveratrol on retinal ganglion cells after optic nerve transection.
Topics: Animals; Benzamides; Cell Survival; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Male; Naphthols; Neuroprotective Agents; Optic Nerve Injuries; Rats; Rats, Sprague-Dawley; Resveratrol; Retinal Ganglion Cells; Sirtuin 1; Stilbenes | 2013 |
Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor.
Topics: 3T3-L1 Cells; Adipogenesis; Alternative Splicing; Animals; Apoptosis; Cell Differentiation; Gene Expression Regulation, Enzymologic; Male; Mice; Mice, Inbred C57BL; Polyphenols; Protein Kinase C-delta; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Transfection | 2013 |
[Resveratrol protects against hydrogen peroxide induced injury in human umbilical vein endothelial cells].
Topics: Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Resveratrol protects rabbit ventricular myocytes against oxidative stress-induced arrhythmogenic activity and Ca2+ overload.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Cells, Cultured; Heart Ventricles; Male; Myocytes, Cardiac; Oxidative Stress; Rabbits; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Pemetrexed downregulates ERCC1 expression and enhances cytotoxicity effected by resveratrol in human nonsmall cell lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Endonucleases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamates; Guanine; Humans; Lung Neoplasms; MAP Kinase Kinase 3; MAP Kinase Kinase 6; p38 Mitogen-Activated Protein Kinases; Pemetrexed; Protein Kinase Inhibitors; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Stilbenes; Time Factors; Transfection | 2013 |
Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes.
Topics: Adipocytes; Antioxidants; Bone Marrow Cells; Cell Differentiation; Cell Respiration; Curcumin; Humans; Hydrogen Peroxide; Mesenchymal Stem Cells; Mitochondria; Organophosphorus Compounds; Oxygen Consumption; Reactive Oxygen Species; Resveratrol; Stilbenes; Ubiquinone | 2013 |
Role of PGC-1α in exercise training- and resveratrol-induced prevention of age-associated inflammation.
Topics: Aging; Animals; Antioxidants; Female; Inflammation; Interleukin-6; Mice; Mice, Knockout; Muscle, Skeletal; Nitric Oxide Synthase Type II; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Protein Carbonylation; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factors; Tumor Necrosis Factor-alpha | 2013 |
Multivariate modular metabolic engineering of Escherichia coli to produce resveratrol from L-tyrosine.
Topics: Acyltransferases; Ammonia-Lyases; Coenzyme A Ligases; Coumaric Acids; Escherichia coli; Escherichia coli Proteins; Fermentation; Metabolic Engineering; Metabolic Networks and Pathways; Multivariate Analysis; Propionates; Resveratrol; Stilbenes; Tyrosine | 2013 |
3,5,4'-Trimethoxystilbene, a natural methoxylated analog of resveratrol, inhibits breast cancer cell invasiveness by downregulation of PI3K/Akt and Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.
Topics: Anticarcinogenic Agents; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Humans; MCF-7 Cells; Neoplasm Invasiveness; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Resveratrol; Stilbenes; Wnt Signaling Pathway | 2013 |
Protective effect of resveratrol against endotoxemia-induced lung injury involves the reduction of oxidative/nitrative stress.
Topics: Acute Lung Injury; Animals; Antioxidants; Disease Models, Animal; Endotoxemia; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Resveratrol; Stilbenes; Superoxide Dismutase | 2014 |
Resveratrol mitigates isoflurane-induced neuroapoptosis by inhibiting the activation of the Akt-regulated mitochondrial apoptotic signaling pathway.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Comet Assay; DNA Damage; In Situ Nick-End Labeling; Isoflurane; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2013 |
Targeting of the purine biosynthesis host cell pathway enhances the activity of tenofovir against sensitive and drug-resistant HIV-1.
Topics: Adenine; Cells, Cultured; Drug Resistance, Viral; Drug Synergism; HIV-1; Host-Pathogen Interactions; Humans; Leukocytes, Mononuclear; Organophosphonates; Purines; Receptors, CCR5; Resveratrol; Reverse Transcriptase Inhibitors; Stilbenes; Tenofovir; Virus Replication | 2013 |
Antitumor effects of naturally occurring oligomeric resveratrol derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Genes, p16; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, Nude; Neoplasms; p38 Mitogen-Activated Protein Kinases; Polymers; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2013 |
Absorption of resveratrol by vascular endothelial cells through passive diffusion and an SGLT1-mediated pathway.
Topics: Animals; Diffusion; Endothelial Cells; Female; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Phlorhizin; Rats; Resveratrol; Sodium-Glucose Transporter 1; Stilbenes; Transfection | 2013 |
The use of calorie restriction mimetics to study aging.
Topics: Aging; Animals; Antioxidants; Biomimetics; Caloric Restriction; Immunosuppressive Agents; Longevity; Male; Mice; Mice, Inbred C57BL; Models, Animal; Resveratrol; Sirolimus; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Postharvest accumulation of resveratrol and piceatannol in sugarcane with enhanced antioxidant activity.
Topics: Antioxidants; Phenols; Plant Extracts; Resveratrol; Saccharum; Stilbenes; Time Factors | 2013 |
Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line.
Topics: Alcohols; Antioxidants; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Freeze Drying; Humans; Osteosarcoma; Polyphenols; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Wine | 2013 |
Proenergetic effects of resveratrol in the murine neuronal cell line Neuro2a.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Energy Metabolism; Fatty Acids; Glucose; Glucose Transporter Type 4; Guanosine Triphosphate; Lactic Acid; Mice; Neurons; Resveratrol; Stilbenes | 2013 |
Resveratrol prevents dendritic cell maturation in response to advanced glycation end products.
Topics: CD4-Positive T-Lymphocytes; Cells, Cultured; Chromatography, Gel; Computational Biology; Dendritic Cells; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Glucose; Glycation End Products, Advanced; Humans; Resveratrol; Stilbenes | 2013 |
Piperine potentiates the antidepressant-like effect of trans-resveratrol: involvement of monoaminergic system.
Topics: Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Benzodioxoles; Brain; Depression; Drug Synergism; Hindlimb Suspension; Mice; Monoamine Oxidase; Motor Activity; Piperidines; Polyunsaturated Alkamides; Resveratrol; Serotonin; Stilbenes; Swimming | 2013 |
Highly efficient biotransformation of polydatin to resveratrol by snailase hydrolysis using response surface methodology optimization.
Topics: Antioxidants; Biotransformation; Glucosides; Humans; Hydrolysis; Resveratrol; Stilbenes; Surface Properties; Temperature; Vitis | 2013 |
Antimicrobial effect of natural polyphenols with or without antibiotics on Chlamydia pneumoniae infection in vitro.
Topics: Anti-Bacterial Agents; Antioxidants; Cell Line, Tumor; Chlamydophila pneumoniae; Clarithromycin; Drug Synergism; Drug Therapy, Combination; Epithelial Cells; Humans; Interleukin-17; Interleukin-23; Microbial Sensitivity Tests; Microbial Viability; Ofloxacin; Quercetin; Resveratrol; Stilbenes | 2014 |
Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2.
Topics: Anilides; Catalytic Domain; Crystallography, X-Ray; Drug Design; Enzyme Activation; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Molecular Structure; Quinone Reductases; Resveratrol; Small Molecule Libraries; Stilbenes | 2013 |
Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Neoplasm; Humans; MicroRNAs; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Stilbenes; Xanthones | 2013 |
Sirtuin-2 activity is required for glioma stem cell proliferation arrest but not necrosis induced by resveratrol.
Topics: Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Glioblastoma; Humans; Necrosis; Neoplastic Stem Cells; Resveratrol; RNA, Small Interfering; Sirtuin 2; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2014 |
Immunoliposome encapsulation increases cytotoxic activity and selectivity of curcumin and resveratrol against HER2 overexpressing human breast cancer cells.
Topics: Antibodies, Monoclonal, Humanized; Anticarcinogenic Agents; Antineoplastic Agents; Biological Availability; Biological Products; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Cell Line, Tumor; Cholesterol; Chromatography, High Pressure Liquid; Curcumin; Drug Compounding; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Humans; Immunoconjugates; Liposomes; Neoplasm Proteins; Particle Size; Phosphatidylcholines; Phosphatidylethanolamines; Receptor, ErbB-2; Resveratrol; Stilbenes; Trastuzumab | 2013 |
Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model.
Topics: Animals; Biological Availability; Brain; Dietary Fats; Disease Models, Animal; Female; Grape Seed Extract; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Synapses; Vitis | 2013 |
Differences in the glucuronidation of resveratrol and pterostilbene: altered enzyme specificity and potential gender differences.
Topics: Biotransformation; Female; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Resveratrol; Sex Factors; Stilbenes; Substrate Specificity | 2014 |
Resveratrol-loaded nanoparticles based on poly(epsilon-caprolactone) and poly(D,L-lactic-co-glycolic acid)-poly(ethylene glycol) blend for prostate cancer treatment.
Topics: Cell Line, Tumor; Cell Survival; Humans; Magnetic Resonance Spectroscopy; Male; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanoparticles; Polyesters; Prostatic Neoplasms; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2013 |
Comparative studies of apoptosis in Xenopus laevis and mouse thymoma cell lines.
Topics: Animals; Apoptosis; Cell Line, Tumor; Immunohistochemistry; Mice; Proto-Oncogene Proteins c-mdm2; Resveratrol; Stilbenes; Thymoma; Tumor Suppressor Protein p53; Ultraviolet Rays; Xenopus laevis | 2013 |
NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration.
Topics: Animals; Apoptosis; Axons; Caspases; Mice; Microfluidics; NAD; Resveratrol; Sirtuin 3; Stilbenes | 2013 |
Synapto-protective drugs evaluation in reconstructed neuronal network.
Topics: Amides; Amino Acid Chloromethyl Ketones; Animals; Axons; Dendrites; Embryo, Mammalian; Enzyme Inhibitors; Mice; Microfluidics; Microscopy, Fluorescence; Models, Neurological; NAD; Nerve Net; Neurodegenerative Diseases; Primary Cell Culture; Pyridines; Resveratrol; Stilbenes; Synapses | 2013 |
Resveratrol protects against vinorelbine-induced vascular endothelial cell injury.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Culture Techniques; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; Microscopy, Fluorescence; Reactive Oxygen Species; Resveratrol; Stilbenes; Vinblastine; Vinorelbine | 2013 |
Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease.
Topics: Animals; Autophagy; Diet, High-Fat; Disease Models, Animal; DNA Primers; Fatty Liver; Inflammation; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Polymerase Chain Reaction; Resveratrol; Stilbenes | 2014 |
Synthesis of resveratrol glycosides by cultured plant cells.
Topics: Biotransformation; Cells, Cultured; Eucalyptus; Glycine max; Glycosides; Gossypium; Resveratrol; Stilbenes | 2013 |
Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury.
Topics: Alanine Transaminase; Aldehydes; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Carbon Tetrachloride; Caspase 3; Caspase 8; Chemical and Drug Induced Liver Injury; Chemokine CXCL10; Cytokines; Hepatocytes; Inflammation Mediators; Liver; Liver Regeneration; Male; Mice; Mice, Inbred C57BL; Necrosis; Phytoalexins; Phytotherapy; Resveratrol; Sesquiterpenes; Stilbenes | 2014 |
Resveratrol attenuates the release of inflammatory cytokines from human bronchial smooth muscle cells exposed to lipoteichoic acid in chronic obstructive pulmonary disease.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Carbazoles; Chemokine CCL2; Cytokines; Dexamethasone; Female; Gram-Positive Bacteria; Granulocyte-Macrophage Colony-Stimulating Factor; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Interleukin-6; Interleukin-8; Lipopolysaccharides; Male; Middle Aged; Myocytes, Smooth Muscle; Pulmonary Disease, Chronic Obstructive; Respiratory System; Resveratrol; Sirtuin 1; Stilbenes; Teichoic Acids | 2014 |
Effects of resveratrol on methotrexate-induced testicular damage in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Catalase; In Situ Nick-End Labeling; Male; Malondialdehyde; Methotrexate; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Testis | 2013 |
Effects of resveratrol on daily rhythms of locomotor activity and body temperature in young and aged grey mouse lemurs.
Topics: Animals; Body Temperature; Cheirogaleidae; Circadian Rhythm; Energy Metabolism; Female; Male; Motor Activity; Resveratrol; Stilbenes | 2013 |
Octreotide-functionalized and resveratrol-loaded unimolecular micelles for targeted neuroendocrine cancer therapy.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Neuroendocrine; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Humans; Micelles; Nanomedicine; Neuroendocrine Tumors; Octreotide; Polyesters; Polyethylene Glycols; Resveratrol; Stilbenes | 2013 |
Evaluation of resveratrol sensitivities and metabolic patterns in human and rat glioblastoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain; Cell Line, Tumor; Cell Proliferation; Enzyme Induction; Glioblastoma; Glucuronides; Glucuronosyltransferase; Humans; Male; Metabolic Detoxication, Phase II; Neoplasm Proteins; Nerve Tissue Proteins; Neurons; Rats; Rats, Wistar; Resveratrol; Species Specificity; Stilbenes; Sulfotransferases; Sulfuric Acid Esters | 2013 |
Synthesis and biological activity of new resveratrol derivative and molecular docking: dynamics studies on NFkB.
Topics: Cell Line, Tumor; Cell Survival; Chemistry Techniques, Synthetic; DNA Fragmentation; Humans; Molecular Docking Simulation; NF-kappa B; Protein Conformation; Protein Stability; Resveratrol; Stilbenes | 2013 |
In silico and biochemical analyses identify quinone reductase 2 as a target of piceatannol.
Topics: Apoptosis; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1B1; Humans; Molecular Docking Simulation; NAD(P)H Dehydrogenase (Quinone); Protein Structure, Tertiary; Quinone Reductases; Resveratrol; RNA Interference; RNA, Small Interfering; Stilbenes | 2013 |
Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway.
Topics: Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Movement; Chromones; Epithelial-Mesenchymal Transition; Humans; Matrix Metalloproteinases; Morpholines; NF-kappa B; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Transforming Growth Factor beta; Vimentin | 2013 |
Effect of lifelong resveratrol supplementation and exercise training on skeletal muscle oxidative capacity in aging mice; impact of PGC-1α.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Citrate (si)-Synthase; DNA, Mitochondrial; Female; Mice; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors; Vascular Endothelial Growth Factor A | 2013 |
Investigation of the distribution and season regularity of resveratrol in Vitis amurensis via HPLC-DAD-MS/MS.
Topics: Chromatography, High Pressure Liquid; Fruit; Plant Extracts; Resveratrol; Seasons; Stilbenes; Tandem Mass Spectrometry; Vitis | 2014 |
Quercetin suppresses invasion and migration of H-Ras-transformed MCF10A human epithelial cells by inhibiting phosphatidylinositol 3-kinase.
Topics: Breast Neoplasms; Cell Line, Transformed; Cell Movement; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Genes, ras; Humans; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins p21(ras); Quercetin; Resveratrol; Signal Transduction; Stilbenes; Wine | 2014 |
Resveratrol stimulates mitochondrial bioenergetics to protect retinal pigment epithelial cells from oxidative damage.
Topics: Adult; Angiogenesis Inhibitors; Animals; Cell Survival; Cytoprotection; Disease Models, Animal; DNA Damage; Energy Metabolism; Enzyme Inhibitors; Female; Humans; Macular Degeneration; Mitochondria; Oxidative Stress; Rats; Rats, Inbred BN; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2013 |
Repeated resveratrol treatment attenuates methamphetamine-induced hyperactivity and [3H]dopamine overflow in rodents.
Topics: Animals; Central Nervous System Stimulants; Cocaine; Corpus Striatum; Dopamine; Drug Antagonism; In Vitro Techniques; Male; Methamphetamine; Mice; Motor Activity; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits NF-kB signaling through suppression of p65 and IkappaB kinase activities.
Topics: Antioxidants; Blotting, Western; Cell Line; Electrophoretic Mobility Shift Assay; HEK293 Cells; Humans; I-kappa B Kinase; Immunoprecipitation; Luciferases; Microscopy, Fluorescence; NF-kappa B; Plasmids; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor RelA; Transcription, Genetic; Translocation, Genetic; Tumor Necrosis Factor-alpha; Ubiquitination | 2013 |
Resveratrol increases cerebral glycogen synthase kinase phosphorylation as well as protein levels of drebrin and transthyretin in mice: an exploratory study.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cerebrum; Dietary Supplements; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mice, Transgenic; Mutant Chimeric Proteins; Mutation; Nerve Tissue Proteins; Neurons; Neuropeptides; Neuroprotective Agents; Phosphorylation; Prealbumin; Presenilin-1; Protein Processing, Post-Translational; Recombinant Proteins; Resveratrol; Specific Pathogen-Free Organisms; Stilbenes | 2014 |
The effects of resveratrol against trifluralin toxicity in the urinary tract of rats.
Topics: Animals; Antioxidants; Apoptosis; Body Weight; Dose-Response Relationship, Drug; Glutathione Peroxidase; In Situ Nick-End Labeling; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Trifluralin; Urinary Tract | 2016 |
Variations in the levels of mulberroside A, oxyresveratrol, and resveratrol in mulberries in different seasons and during growth.
Topics: Disaccharides; Morus; Plant Extracts; Resveratrol; Seasons; Stilbenes | 2013 |
Resveratrol as a pan-HDAC inhibitor alters the acetylation status of histone [corrected] proteins in human-derived hepatoblastoma cells.
Topics: Acetylation; Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chick Embryo; Computer Simulation; Hepatoblastoma; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Liver Neoplasms; Molecular Docking Simulation; Resveratrol; Stilbenes | 2013 |
Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons.
Topics: Animals; Catechin; Cerebral Cortex; Curcumin; Lysosomal Membrane Proteins; Molecular Chaperones; Neurons; Primary Cell Culture; Rats; Resveratrol; Stilbenes; tau Proteins; Up-Regulation | 2013 |
Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia.
Topics: Animals; Crassulaceae; Gallic Acid; Homeodomain Proteins; Hyperglycemia; Insulin; Liver; Lysine; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Pancreas; Plant Extracts; PPAR gamma; Resveratrol; Stilbenes; Taiwan; Trans-Activators | 2013 |
SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway.
Topics: Adult; Amyloid beta-Peptides; Antioxidants; Blood-Retinal Barrier; Cell Survival; Enzyme Assays; Gene Silencing; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Interleukin-6; Interleukin-8; Macular Degeneration; Matrix Metalloproteinase 9; NF-kappa B; Primary Cell Culture; Real-Time Polymerase Chain Reaction; Resveratrol; Retinal Pigment Epithelium; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes | 2013 |
Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.
Topics: Antimicrobial Cationic Peptides; Cathelicidins; Cell Line; Cyclic AMP; Drug Evaluation, Preclinical; Drug Synergism; Gene Expression Regulation; Humans; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Small Molecule Libraries; Stilbenes; Vitamin D | 2014 |
Regulation of FOXOs and p53 by SIRT1 modulators under oxidative stress.
Topics: AMP-Activated Protein Kinases; Animals; Antimycin A; Apoptosis; Cell Cycle Proteins; Cell Line; Cell Proliferation; Enzyme Activation; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Knockdown Techniques; Humans; Hydrogen Peroxide; Mice; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Tumor Suppressor Protein p53 | 2013 |
Protective effects of resveratrol in experimental retinal detachment.
Topics: Animals; Apoptosis; Caspases; Forkhead Transcription Factors; Male; Photoreceptor Cells; Rats; Resveratrol; Retinal Detachment; Signal Transduction; Stilbenes; Up-Regulation | 2013 |
Resveratrol induces hepatic mitochondrial biogenesis through the sequential activation of nitric oxide and carbon monoxide production.
Topics: Animals; Antioxidants; Carbon Monoxide; Disease Models, Animal; Hep G2 Cells; Humans; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Nitric Oxide; Resveratrol; Sepsis; Stilbenes; Tumor Cells, Cultured | 2014 |
Preparation of resveratrol-enriched grape juice from ultrasonication treated grape fruits.
Topics: Anthocyanins; Beverages; Hydrogen-Ion Concentration; Resveratrol; Sonication; Stilbenes; Vitis | 2014 |
Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells.
Topics: Animals; B-Lymphocytes, Regulatory; Female; Forkhead Transcription Factors; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Resveratrol; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2013 |
Experimental and computational studies on newly synthesized resveratrol derivative: a new method for cancer chemoprevention and therapeutics?
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Cell Line, Tumor; DNA; DNA Fragmentation; Fas Ligand Protein; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Molecular Docking Simulation; Neoplasms; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Binding; Receptors, Tumor Necrosis Factor; Resveratrol; Stereoisomerism; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
AMP-activated protein kinase as a promoting factor, but complement and thrombin as limiting factors for acquisition of cytoprotection: implications for induction of accommodation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; CD55 Antigens; CD59 Antigens; Cell Line; Complement System Proteins; Cytoprotection; Cytotoxicity, Immunologic; Graft Rejection; Humans; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Thrombin; Transplantation Immunology | 2013 |
Synergistic anti-proliferative effect of resveratrol and etoposide on human hepatocellular and colon cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2013 |
Targeting sphingosine kinase 1 (SphK1) and apoptosis by colon-specific delivery formula of resveratrol in treatment of experimental ulcerative colitis in rats.
Topics: Animals; Apoptosis; Caspase 3; Chemistry, Pharmaceutical; Colitis, Ulcerative; Colon; DNA Fragmentation; Drug Delivery Systems; Humans; Molecular Targeted Therapy; Organ Specificity; Oxazolone; Peroxidase; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue.
Topics: Antineoplastic Agents; Apoptosis; Aryl Hydrocarbon Hydroxylases; Caspases; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Humans; Resveratrol; Stilbenes | 2013 |
Effect of resveratrol and tiron on the inactivation of glyceraldehyde-3- phosphate dehydrogenase induced by superoxide anion radical.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Antioxidants; Enzyme Activation; Glyceraldehyde-3-Phosphate Dehydrogenases; Molecular Docking Simulation; Oxidants; Rabbits; Resveratrol; Stilbenes; Superoxides; Xanthine Oxidase | 2014 |
Curcumin and resveratrol act by different ways on NADPH oxidase activity and reactive oxygen species produced by equine neutrophils.
Topics: Animals; Cell-Free System; Curcumin; Enzyme Inhibitors; Horses; Humans; Luminescent Measurements; NADPH Oxidases; Neutrophils; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Identification of carbonyl reductase 1 as a resveratrol-binding protein by affinity chromatography using 4'-amino-3,5-dihydroxy-trans-stilbene.
Topics: Alcohol Oxidoreductases; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Binding, Competitive; Breast Neoplasms; Chromatography, Affinity; Doxorubicin; Female; Humans; Hydroquinones; MCF-7 Cells; NADP; Phytotherapy; Plant Extracts; Protein Binding; Resveratrol; Stilbenes | 2013 |
Resveratrol suppresses the STAT3 signaling pathway and inhibits proliferation of high glucose-exposed HepG2 cells partly through SIRT1.
Topics: Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Diabetes Mellitus, Type 2; Gene Expression Regulation, Neoplastic; Glucose; Hep G2 Cells; Humans; Liver Neoplasms; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; STAT3 Transcription Factor; Stilbenes | 2013 |
Diverse plant extracts and trans-resveratrol inhibit biofilm formation and swarming of Escherichia coli O157:H7.
Topics: Biofilms; Cell Adhesion; Chromatography, High Pressure Liquid; Escherichia coli O157; HT29 Cells; Humans; Microbial Sensitivity Tests; Plankton; Plant Extracts; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Transcription, Genetic | 2013 |
Substrates and enzyme activities related to biotransformation of resveratrol from phenylalanine by Alternaria sp. MG1.
Topics: Alternaria; Biotransformation; Coenzyme A Ligases; Fungal Proteins; Phenylalanine; Phenylalanine Ammonia-Lyase; Resveratrol; Stilbenes; Substrate Specificity; Trans-Cinnamate 4-Monooxygenase | 2013 |
Transferrin modified PEG-PLA-resveratrol conjugates: in vitro and in vivo studies for glioma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Brain; Cell Line, Tumor; Cell Proliferation; Drug Carriers; Glioma; Lactic Acid; Male; Molecular Targeted Therapy; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Rats; Resveratrol; Stilbenes; Survival Analysis; Transferrin; Xenograft Model Antitumor Assays | 2013 |
Resveratrol and P-glycoprotein inhibitors enhance the anti-skin cancer effects of ursolic acid.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Survival; Cyclosporine; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Mice; Resveratrol; Rhodamine 123; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid; Verapamil | 2013 |
Resveratrol Inhibits CD4+ T cell activation by enhancing the expression and activity of Sirt1.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blotting, Western; CD4-Positive T-Lymphocytes; Cell Nucleus; Cell Proliferation; Collagen; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
A healthier approach to clinical trials evaluating resveratrol for primary prevention of age‐related diseases in healthy populations.
Topics: Aging; Biomarkers; Biosensing Techniques; Dose-Response Relationship, Drug; Homeostasis; Humans; Models, Biological; Research Design; Resveratrol; Stilbenes; Treatment Outcome | 2013 |
Long-term resveratrol treatment prevents ovariectomy-induced osteopenia in rats without hyperplastic effects on the uterus.
Topics: Animals; Antioxidants; Biomarkers; Bone Density; Bone Density Conservation Agents; Dietary Supplements; Disease Models, Animal; Endometrial Hyperplasia; Endometrium; Estrogen Replacement Therapy; Female; Femur; Humans; Osteoporosis, Postmenopausal; Osteoprotegerin; Phytoestrogens; Random Allocation; RANK Ligand; Rats; Rats, Wistar; Resveratrol; Stilbenes; Time Factors | 2014 |
Scavenging of hydroxyl radical by resveratrol and related natural stilbenes after hydrogen peroxide attack on DNA.
Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Cytokinesis; DNA; DNA Damage; Free Radical Scavengers; Hydrogen Peroxide; Models, Molecular; Molecular Conformation; Resveratrol; Stilbenes | 2013 |
Inhibition of oxidized-phospholipid-induced vascular smooth muscle cell proliferation by resveratrol is associated with reducing Cx43 phosphorylation.
Topics: Animals; Aorta; Atherosclerosis; Cell Cycle; Cell Line; Cell Proliferation; Cells, Cultured; Connexin 43; Down-Regulation; Humans; Myocytes, Smooth Muscle; Oxidation-Reduction; Phospholipids; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Submaximal ADP-stimulated respiration is impaired in ZDF rats and recovered by resveratrol.
Topics: Adenine Nucleotide Translocator 2; Adenosine Diphosphate; Animals; Cell Respiration; Diabetes Mellitus, Type 2; Glutathione; Glutathione Disulfide; Hydrogen Peroxide; Insulin Resistance; Male; Mitochondria; Muscle, Skeletal; Rats; Rats, Zucker; Resveratrol; Stilbenes | 2013 |
Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.
Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Glucuronides; Humans; Intracellular Space; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Sulfates | 2013 |
Resveratrol mainly stimulates the glycolytic ATP synthesis flux and not the mitochondrial one: a saturation transfer NMR study in perfused and isolated rat liver.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Glycolysis; Liver; Magnetic Resonance Spectroscopy; Male; Mitochondria; Phosphorylation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2013 |
Resveratrol suppresses cell proliferation via inhibition of STAT3 phosphorylation and Mcl-1 and cIAP-2 expression in HTLV-1-infected T cells.
Topics: Antimutagenic Agents; Baculoviral IAP Repeat-Containing 3 Protein; Cell Proliferation; Cells, Cultured; Drug Evaluation, Preclinical; Gene Expression Regulation; HTLV-I Infections; Human T-lymphotropic virus 1; Humans; Inhibitor of Apoptosis Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Phosphorylation; Protein Kinases; Resveratrol; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes; Ubiquitin-Protein Ligases | 2013 |
Resveratrol exacerbates both autoimmune and viral models of multiple sclerosis.
Topics: Animals; Autoimmunity; Axons; Disease Models, Animal; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Humans; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Nerve Degeneration; Neuroprotective Agents; Resveratrol; Stilbenes; Theilovirus; Virulence | 2013 |
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.
Topics: Adipocytes; Adipose Tissue, White; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrates; Cell Line; Diet, High-Fat; Inflammation; Insulin; Macaca mulatta; Male; Mice; NF-kappa B; Obesity; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcriptome; Viscera | 2013 |
Inhibition of STIM1 phosphorylation underlies resveratrol-induced inhibition of store-operated calcium entry.
Topics: Calcium; Calcium Channels; Calcium Signaling; Cell Culture Techniques; HEK293 Cells; Humans; MAP Kinase Signaling System; Membrane Glycoproteins; Microtubule-Associated Proteins; ORAI1 Protein; Phosphorylation; Protein Binding; Resveratrol; Stilbenes; Stromal Interaction Molecule 1; Transfection | 2013 |
Critical role of FoxO3a in alcohol-induced autophagy and hepatotoxicity.
Topics: Animals; Autophagy; Central Nervous System Depressants; Enzyme Inhibitors; Ethanol; Fatty Liver; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation; Hepatocytes; Liver; Liver Diseases, Alcoholic; Mice; Mice, Knockout; Resveratrol; Sirtuin 1; Stilbenes | 2013 |
Characterization of a novel multifunctional resveratrol derivative for the treatment of atrial fibrillation.
Topics: Action Potentials; Adult; Aged; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Antioxidants; Atrial Fibrillation; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Excitation Contraction Coupling; G Protein-Coupled Inwardly-Rectifying Potassium Channels; HEK293 Cells; Humans; Kv1.5 Potassium Channel; Male; Middle Aged; Myocardial Contraction; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; NFATC Transcription Factors; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium Channel Blockers; Stilbenes; Transfection | 2014 |
Neuroprotective effect of resveratrol on arsenic trioxide-induced oxidative stress in feline brain.
Topics: Animals; Antineoplastic Agents; Antioxidants; Arsenic Trioxide; Arsenicals; Cats; Cerebral Cortex; Cytoprotection; Environmental Pollutants; Female; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits hydrogen peroxide-induced apoptosis in endothelial cells via the activation of PI3K/Akt by miR-126.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Flow Cytometry; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; MicroRNAs; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2014 |
Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model.
Topics: Acetylcysteine; Animals; Antioxidants; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Flow Cytometry; Free Radical Scavengers; Mice; Mice, Knockout; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines.
Topics: 3T3 Cells; Animals; Antineoplastic Agents, Phytogenic; Azetidines; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; MCF-7 Cells; Mice; Resveratrol; Stilbenes | 2013 |
5,6-Dihydro-5-aza-2'-deoxycytidine potentiates the anti-HIV-1 activity of ribonucleotide reductase inhibitors.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Deoxycytidine; Enzyme Inhibitors; Genes, Reporter; Green Fluorescent Proteins; HIV-1; Humans; Luminescent Proteins; Mutation; Red Fluorescent Protein; Resveratrol; Ribonucleotide Reductases; Stilbenes; Viral Proteins | 2013 |
Encapsulation of mixtures of tuna oil, tributyrin and resveratrol in a spray dried powder formulation.
Topics: Animals; Chemistry, Pharmaceutical; Drug Stability; Emulsions; Fish Oils; Particle Size; Powders; Resveratrol; Stilbenes; Triglycerides; Tuna | 2013 |
Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Catechin; Cell Death; Cell Line, Tumor; Cell Proliferation; Chelating Agents; Copper; Drug Screening Assays, Antitumor; Humans; Luteolin; Phenanthrolines; Polyphenols; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Mechanism of resveratrol on the promotion of induced pluripotent stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Hypoxia-Inducible Factor 1, alpha Subunit; Induced Pluripotent Stem Cells; Mice; Octamer Transcription Factor-3; Proto-Oncogene Proteins c-bcl-2; Resveratrol; SOXB1 Transcription Factors; Stilbenes | 2013 |
Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: the HPA axis, BDNF expression and phosphorylation of ERK.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Extracellular Signal-Regulated MAP Kinases; Hindlimb Suspension; Hypothalamo-Hypophyseal System; Male; Mice; Phosphorylation; Pituitary-Adrenal System; Resveratrol; Stilbenes; Stress, Physiological; Swimming | 2013 |
Resveratrol pretreatment attenuates the isoflurane-induced cognitive impairment through its anti-inflammation and -apoptosis actions in aged mice.
Topics: Age Factors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Cognition Disorders; Freezing Reaction, Cataleptic; Hippocampus; Interleukin-1beta; Isoflurane; Male; Mice; Mice, Inbred C57BL; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
New phenanthrene derivatives with nitric oxide inhibitory and radical-scavenging activities from Pholidota imbricata Hook.
Topics: Animals; Antioxidants; Biphenyl Compounds; Drugs, Chinese Herbal; Flavonoids; Free Radical Scavengers; Macrophages; Mice; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Orchidaceae; Phenanthrenes; Picrates; Quercetin; Resveratrol; Stilbenes | 2014 |
Preliminary separation and purification of resveratrol from extract of peanut (Arachis hypogaea) sprouts by macroporous adsorption resins.
Topics: Adsorption; Arachis; Plant Extracts; Resins, Synthetic; Resveratrol; Stilbenes; Thermodynamics | 2014 |
Strategies to improve the solubility and stability of stilbene antioxidants: a comparative study between cyclodextrins and bile acids.
Topics: Antioxidants; Bile Acids and Salts; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Cyclodextrins; Magnetic Resonance Spectroscopy; Resveratrol; Solubility; Solutions; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Ray Diffraction | 2014 |
Phenolic composition and antioxidant activity in sparkling wines: modulation by the ageing on lees.
Topics: Antioxidants; beta-Glucosidase; Caffeic Acids; Coumaric Acids; Food Handling; Gallic Acid; Glucosides; Phenylethyl Alcohol; Polyphenols; Resveratrol; Stilbenes; Wine | 2014 |
Food for thought--resveratrol vs. exercise training.
Topics: Cardiovascular System; Exercise; Humans; Male; Resveratrol; Stilbenes | 2013 |
Recent data do not provide evidence that resveratrol causes 'mainly negative' or 'adverse' effects on exercise training in humans.
Topics: Cardiovascular System; Exercise; Humans; Male; Resveratrol; Stilbenes | 2013 |
Reply from Lasse Gliemann, Jakob Schmidt, Jesper Olesen, Rasmus Sjørup Biensø, Sebastian Louis Peronard, Simon Udsen Grandjean, Stefan Peter Mortensen, Michael Nyberg, Jens Bangsbo, Henriette Pilegaard and Ylva Hellsten.
Topics: Cardiovascular System; Exercise; Humans; Male; Resveratrol; Stilbenes | 2013 |
Resveratrol and food effects on lifespan and reproduction in the model crustacean Daphnia.
Topics: Animals; Caloric Restriction; Classification; Daphnia; Fertility; Life Cycle Stages; Longevity; Polymorphism, Genetic; Reproduction; Resveratrol; Stilbenes | 2014 |
Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: preventive effects of resveratrol.
Topics: Animals; Anticarcinogenic Agents; BRCA1 Protein; Breast; Breast Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genes, BRCA1; Maternal Exposure; Polychlorinated Dibenzodioxins; Pregnancy; Promoter Regions, Genetic; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Teratogens | 2015 |
Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell.
Topics: Antioxidants; Apoptosis; Blotting, Western; Caco-2 Cells; Cell Cycle; Cell Differentiation; Flow Cytometry; Glucosides; Humans; Microscopy, Confocal; Resveratrol; Stilbenes | 2013 |
Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells.
Topics: Acetylcysteine; Antioxidants; Apoptosis; beta-Galactosidase; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cellular Senescence; DNA Breaks, Double-Stranded; Humans; Lung Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; Stilbenes; TOR Serine-Threonine Kinases | 2013 |
Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi.
Topics: Aging; Animals; Antioxidants; Blotting, Western; Cerebral Ventricles; Cognition; Cognition Disorders; Disease Models, Animal; Fluorometry; Hippocampus; Injections, Intraperitoneal; Male; MAP Kinase Signaling System; Phosphorylation; Rabbits; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Streptozocin; tau Proteins; Vasodilator Agents | 2014 |
JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide.
Topics: Animals; Anti-Inflammatory Agents; Base Sequence; Benzamides; Cell Line; DNA Primers; Humans; Inflammation Mediators; Janus Kinase 2; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; Transcription Factors | 2013 |
Anti-nephrolithic potential of resveratrol via inhibition of ROS, MCP-1, hyaluronan and osteopontin in vitro and in vivo.
Topics: Animals; Antioxidants; Calcium Oxalate; Cell Movement; Cell Survival; Cells, Cultured; Chemokine CCL2; Down-Regulation; Ethylene Glycol; Humans; Hyaluronic Acid; Kidney; Kidney Calculi; Male; Malondialdehyde; NADP; NADPH Oxidases; Osteopontin; Oxalic Acid; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Transforming Growth Factors; Wound Healing | 2013 |
RETRACTED: Role of mammalian sirtuin 1 (SIRT1) in lipids metabolism and cell proliferation of goose primary hepatocytes.
Topics: Animals; Cell Proliferation; Cells, Cultured; Feeding Behavior; Geese; Gene Expression Regulation; Hepatocytes; Lipid Metabolism; Liver; Male; Mammals; Niacinamide; Resveratrol; RNA, Messenger; Sirolimus; Sirtuin 1; Stilbenes | 2014 |
Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Autophagy; Carbazoles; Cyclic AMP; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoquinolines; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Sulfonamides; Tumor Necrosis Factor-alpha; Vasculitis | 2013 |
CFTR chloride channel is a molecular target of the natural cancer preventive agent resveratrol.
Topics: Animals; Anticarcinogenic Agents; Cells, Cultured; Colon; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Diffusion Chambers, Culture; DNA, Complementary; Intestinal Mucosa; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transfection | 2013 |
cis-Resveratrol produces anti-inflammatory effects by inhibiting canonical and non-canonical inflammasomes in macrophages.
Topics: Antioxidants; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cytokines; Dinoprostone; Endoplasmic Reticulum Stress; Humans; Inflammasomes; Interleukin-1beta; Macrophages; Reactive Oxygen Species; Resveratrol; Stereoisomerism; Stilbenes | 2014 |
Molecular interactions of hemoglobin with resveratrol: potential protective antioxidant role and metabolic adaptations of the erythrocyte.
Topics: Antioxidants; Erythrocytes; Hemoglobins; Humans; Lipid Peroxidation; Models, Molecular; Resveratrol; Stilbenes | 2014 |
Resveratrol Interferes with Fura-2 Intracellular Calcium Measurements.
Topics: Calcium; Cell Line, Tumor; Fura-2; Humans; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2014 |
Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Deoxyguanosine; Fibronectins; Fibrosis; Intercellular Adhesion Molecule-1; Kidney; Kidney Glomerulus; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Resveratrol; Smad3 Protein; Stilbenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ureteral Obstruction | 2014 |
Model-based identification of drug targets that revert disrupted metabolism and its application to ageing.
Topics: Aging; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Algorithms; Caloric Restriction; Computer Simulation; Eicosanoids; Gene Expression Regulation, Fungal; Genome, Fungal; Genome, Human; Hormesis; Humans; Longevity; Metabolic Networks and Pathways; Models, Biological; Molecular Targeted Therapy; Reactive Oxygen Species; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Stilbenes | 2013 |
Structural insights into Resveratrol's antagonist and partial agonist actions on estrogen receptor alpha.
Topics: Animals; Binding Sites; Diethylstilbestrol; Dimerization; Estradiol; Estrogen Receptor alpha; Fulvestrant; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Dynamics Simulation; Phytoestrogens; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Resveratrol; Stilbenes; Tamoxifen | 2013 |
Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cell Proliferation; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Mice; Mice, Inbred BALB C; Multidrug Resistance-Associated Proteins; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tissue Distribution; Tumor Cells, Cultured | 2014 |
Resveratrol protects the brain of obese mice from oxidative damage.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Brain; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mice, Obese; Neuroprotective Agents; Obesity; Oxidative Stress; Resveratrol; Stilbenes; Thinness | 2013 |
Resveratrol and EGCG bind directly and distinctively to miR-33a and miR-122 and modulate divergently their levels in hepatic cells.
Topics: Animals; ATP Binding Cassette Transporter 1; Catechin; Cell Line, Tumor; Fatty Acid Synthases; Flavonoids; Humans; Liver; MicroRNAs; Plant Extracts; Polyphenols; Rats; Resveratrol; Sterol Regulatory Element Binding Protein 2; Stilbenes; Vitis | 2014 |
The cell membrane is the main target of resveratrol as shown by interdisciplinary biomolecular/cellular and biophysical approaches.
Topics: Animals; Apoptosis; Biological Transport; Cell Cycle; Cell Line; Cell Membrane; Cell Survival; Dose-Response Relationship, Drug; Kinetics; Mice; Phosphatidylserines; Resveratrol; Stilbenes | 2014 |
Resveratrol and desferoxamine protect human OxLDL-treated granulosa cell subtypes from degeneration.
Topics: Antioxidants; Cell Death; Cells, Cultured; Cytoprotection; Deferoxamine; Female; Granulosa Cells; Humans; Lipoproteins, LDL; Oxidative Stress; Resveratrol; Stilbenes | 2014 |
Comparative analyses of stilbenoids in canes of major Vitis vinifera L. cultivars.
Topics: Benzofurans; Chromatography, Liquid; Phenols; Plant Stems; Polyphenols; Resveratrol; Species Specificity; Stilbenes; Vitis | 2013 |
Resveratrol prevents suppression of regulatory T-cell production, oxidative stress, and inflammation of mice prone or resistant to high-fat diet-induced obesity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Body Weight; Cytokines; Diet, High-Fat; Dietary Fats; Dietary Supplements; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Obesity; Oxidative Stress; Phytotherapy; Plant Extracts; Receptors, Aryl Hydrocarbon; Resveratrol; Spleen; Stilbenes; T-Lymphocytes, Regulatory | 2013 |
Resveratrol stabilized gold nanoparticles enable surface loading of doxorubicin and anticancer activity.
Topics: Antineoplastic Agents; Biocompatible Materials; Cell Line, Tumor; Doxorubicin; Fibroblasts; Gold; Humans; Metal Nanoparticles; Particle Size; Resveratrol; Solutions; Spectrometry, X-Ray Emission; Spectrophotometry, Ultraviolet; Stilbenes; Surface Properties; X-Ray Diffraction | 2014 |
Liposomes as carriers of the lipid soluble antioxidant resveratrol: evaluation of amelioration of oxidative stress by additional antioxidant vitamin.
Topics: Amidines; Antioxidants; Area Under Curve; Ascorbic Acid; Cell Survival; Coloring Agents; Drug Carriers; Free Radical Scavengers; Humans; Indicators and Reagents; Leukocytes; Liposomes; Luminescence; Luminol; Oxidative Stress; Particle Size; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Vitamins | 2013 |
Resveratrol induces a mitochondrial complex I-dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
Topics: Animals; Electron Transport Complex I; Enzyme Activation; Hep G2 Cells; Hepatocytes; Humans; Mice; Mice, Inbred C57BL; Mitochondria, Liver; NAD; Oxidation-Reduction; Resveratrol; Sirtuin 3; Stilbenes | 2013 |
Resveratrol--a potential inhibitor of biofilm formation in Vibrio cholerae.
Topics: Bacterial Proteins; Biofilms; Dose-Response Relationship, Drug; Molecular Docking Simulation; Plant Extracts; Resveratrol; Stilbenes; Trans-Activators; Vibrio cholerae; Vibrio Infections; Vitis | 2014 |
Resveratrol alters the lipid composition, metabolism and peroxide level in senescent rat hepatocytes.
Topics: Acetates; Aging; Animals; Cell Membrane; Fatty Acids; Fluorescence; Glutathione; Hepatocytes; Lipid Metabolism; Lipid Peroxides; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Sphingolipids; Stilbenes | 2014 |
Resveratrol prevents impaired cognition induced by chronic unpredictable mild stress in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognition Disorders; Corticosterone; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Male; Maze Learning; Neuroprotective Agents; Phosphorylation; Prefrontal Cortex; Rats; Recognition, Psychology; Resveratrol; Stilbenes; Stress, Psychological | 2014 |
Resveratrol self-emulsifying system increases the uptake by endothelial cells and improves protection against oxidative stress-mediated death.
Topics: Animals; Cattle; Cell Death; Cells, Cultured; Cytoprotection; Emulsifying Agents; Endothelial Cells; Oxidative Stress; Resveratrol; Stilbenes | 2014 |
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells.
Topics: Astrocytes; Cell Line, Tumor; Cell Survival; Dipeptides; Glutathione; Homocysteine; Humans; Hydroquinones; Isothiocyanates; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; Stilbenes; Sulfoxides; Thioctic Acid | 2013 |
Resveratrol protects mouse oocytes from methylglyoxal-induced oxidative damage.
Topics: Analysis of Variance; Animals; DNA Breaks, Double-Stranded; Female; Fluorescent Antibody Technique; Glycation End Products, Advanced; Lipid Peroxidation; Mice; Microscopy, Confocal; Oocytes; Oxidative Stress; Pyruvaldehyde; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
The effect of resveratrol in combination with irradiation and chemotherapy: study using Merkel cell carcinoma cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Merkel Cell; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Cisplatin; Dose-Response Relationship, Drug; Etoposide; Humans; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
Antidepressant-like effect of resveratrol: involvement of antioxidant effect and peripheral regulation on HPA axis.
Topics: Animals; Antidepressive Agents; Antioxidants; Base Sequence; Cell Line, Tumor; Corticosterone; DNA Primers; Humans; Hypothalamo-Hypophyseal System; Male; Malondialdehyde; Pituitary-Adrenal System; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Resveratrol inhibits the epithelial sodium channel via phopshoinositides and AMP-activated protein kinase in kidney collecting duct cells.
Topics: Amiloride; AMP-Activated Protein Kinases; Animals; Cell Line; Cells, Cultured; Epithelial Sodium Channels; Immunoblotting; Kidney Tubules, Collecting; Mice; Phosphatidylinositols; Resveratrol; RNA, Small Interfering; Stilbenes | 2013 |
Bioavailability of encapsulated resveratrol into nanoemulsion-based delivery systems.
Topics: Biological Availability; Caco-2 Cells; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Emulsions; Humans; Particle Size; Permeability; Resveratrol; Stilbenes | 2014 |
SIRT1 suppresses cellular accumulation of β-TrCP E3 ligase via protein degradation.
Topics: beta-Transducin Repeat-Containing Proteins; Glucose; HCT116 Cells; HEK293 Cells; HeLa Cells; Humans; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Proteolysis; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Transcription, Genetic; Ubiquitin-Protein Ligases | 2013 |
FERM domain promotes resveratrol-induced apoptosis in endothelial cells via inhibition of NO production.
Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Cytoskeletal Proteins; Cytosol; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Membrane Proteins; Microfilament Proteins; Nitric Oxide; Nitric Oxide Synthase Type III; Resveratrol; Stilbenes | 2013 |
Copper and resveratrol attenuates serum catalase, glutathione peroxidase, and element values in rats with DMBA-induced mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antidotes; Antioxidants; Carcinogens; Catalase; Copper; Copper Sulfate; Female; Glutathione Peroxidase; Mammary Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
Resveratrol protects DAergic PC12 cells from high glucose-induced oxidative stress and apoptosis: effect on p53 and GRP75 localization.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Dopaminergic Neurons; Glucose; HSP70 Heat-Shock Proteins; Membrane Proteins; Oxidative Stress; PC12 Cells; Rats; Resveratrol; Stilbenes; Superoxides; Tumor Suppressor Protein p53 | 2014 |
Resveratrol suppresses cancer cell glucose uptake by targeting reactive oxygen species-mediated hypoxia-inducible factor-1α activation.
Topics: Animals; Biological Transport; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; Gene Expression Regulation, Neoplastic; Glucose; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mice; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Effects of resveratrol on vitrified porcine oocytes.
Topics: Animals; Annexin A5; Apoptosis; Benzimidazoles; Caspases; Cryopreservation; Enzyme Activation; Female; Microscopy, Fluorescence; Oocytes; Phosphatidylserines; Propidium; Resveratrol; Staining and Labeling; Stilbenes; Sus scrofa | 2013 |
The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.
Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Apoptosis; Caspase 12; Caspase Inhibitors; Cell Line; Central Nervous System Depressants; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Ethanol; Hepatocytes; Humans; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
[Resveratrol did not prevent sevoflurane-induced neuroapoptosis in the neonatal mice brain].
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Antioxidants; Apoptosis; Brain; Methyl Ethers; Mice; Mice, Inbred C57BL; Resveratrol; Sevoflurane; Stilbenes | 2013 |
Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Blood Glucose; Glucose Tolerance Test; Homeostasis; Insulin; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Polychlorinated Biphenyls; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes | 2013 |
Chemopreventive effects of resveratrol in a rat model of cerulein-induced acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Ceruletide; Corticosterone; Female; Glutathione Peroxidase; Interleukin-10; Interleukin-1beta; Lipase; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2014 |
Resveratrol contributes to chemosensitivity of malignant mesothelioma cells with activation of p53.
Topics: Adenine Nucleotides; Anticarcinogenic Agents; Antineoplastic Agents; Arabinonucleosides; Base Sequence; Cell Line, Tumor; Clofarabine; DNA Primers; G1 Phase; Genes, p53; Humans; Mesothelioma; Oncogene Proteins; Polymerase Chain Reaction; Resveratrol; Stilbenes | 2014 |
Exploring Leishmania donovani 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) as a potential drug target by biochemical, biophysical and inhibition studies.
Topics: Amino Acid Sequence; Atorvastatin; Cholesterol; Cloning, Molecular; DNA, Protozoan; Drug Delivery Systems; Ergosterol; Gene Expression Regulation, Enzymologic; Genes, Protozoan; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leishmania donovani; Molecular Sequence Data; Open Reading Frames; Protein Structure, Secondary; Pyrroles; Recombinant Proteins; Resveratrol; Sequence Analysis, DNA; Simvastatin; Stilbenes | 2014 |
Resveratrol attenuates cisplatin renal cortical cytotoxicity by modifying oxidative stress.
Topics: Aldehydes; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Survival; Cisplatin; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Synthetic resveratrol analogue, 3,3',4,4',5,5'-hexahydroxy-trans-stilbene, accelerates senescence in peritoneal mesothelium and promotes senescence-dependent growth of gastrointestinal cancers.
Topics: Carcinogenesis; Cell Line, Tumor; Cellular Senescence; Epithelium; Gastrointestinal Neoplasms; Humans; Oxidative Stress; Peritoneal Neoplasms; Peritoneum; Pyrogallol; Resveratrol; Stilbenes | 2013 |
Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses.
Topics: 4-Nitroquinoline-1-oxide; AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Female; Grape Seed Extract; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Tongue; Tongue Neoplasms | 2015 |
The comparative analysis of the potential relationship between resveratrol and stilbene synthase gene family in the development stages of grapes (Vitis quinquangularis and Vitis vinifera).
Topics: Acyltransferases; Amino Acid Sequence; Cloning, Molecular; Genes, Plant; Molecular Sequence Data; Resveratrol; Sequence Homology, Amino Acid; Species Specificity; Stilbenes; Vitis | 2014 |
Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.
Topics: Animals; Cardiomegaly; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzymes; Gene Expression Regulation; Imidazoles; Indoles; Male; Myocytes, Cardiac; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Sunitinib | 2014 |
Resveratrol delays Wallerian degeneration in a NAD(+) and DBC1 dependent manner.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal; Humans; In Vitro Techniques; Mice; NAD; Neurofilament Proteins; Neurons; Resveratrol; RNA-Binding Proteins; Sciatic Nerve; Sirtuin 1; Stilbenes; Time Factors; Transfection; Wallerian Degeneration | 2014 |
Simultaneous determination of 14 phenolic compounds in grape canes by HPLC-DAD-UV using wavelength switching detection.
Topics: Catechin; Chromatography, High Pressure Liquid; Coumarins; Flavonoids; Phenols; Quercetin; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2013 |
Resveratrol and its metabolites inhibit pro-inflammatory effects of lipopolysaccharides in U-937 macrophages in plasma-representative concentrations.
Topics: Anti-Inflammatory Agents; Down-Regulation; Humans; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophages; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; U937 Cells | 2014 |
1,3-Bis(2-chloroethyl)-1-nitrosourea enhances the inhibitory effect of resveratrol on 5-fluorouracil sensitive/resistant colon cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Carmustine; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Colonic Neoplasms; DNA Damage; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; HCT116 Cells; Humans; Resveratrol; Stilbenes | 2013 |
Resveratrol couples apoptosis with autophagy in UVB-irradiated HaCaT cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Caspase 8; Cell Line, Transformed; Cell Proliferation; Humans; Hydrogen Peroxide; Membrane Proteins; Microtubule-Associated Proteins; Oxidative Stress; Phagosomes; Poly(ADP-ribose) Polymerases; Proteolysis; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Ultraviolet Rays | 2013 |
Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Autophagy; Carcinoma, Squamous Cell; Caspase 12; Caspases; Caspases, Initiator; Cell Line, Tumor; Ceramides; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Humans; Nasopharyngeal Neoplasms; Resveratrol; Stilbenes | 2014 |
Lipid-core nanocapsules improve the effects of resveratrol against Abeta-induced neuroinflammation.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cells, Cultured; Drug Synergism; Encephalitis; Hippocampus; Inflammation; Lipids; Male; Nanocapsules; Neurons; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes | 2013 |
Production of pinostilbene compounds by the expression of resveratrol O-methyltransferase genes in Escherichia coli.
Topics: Base Sequence; DNA, Plant; Escherichia coli; Gene Expression; Genes, Plant; Methylation; Methyltransferases; Molecular Sequence Data; Plant Proteins; Recombinant Proteins; Resveratrol; Sorghum; Stilbenes; Vitis | 2014 |
Resveratrol regulates autophagy signaling in chronically ischemic myocardium.
Topics: Animals; Apoptosis Regulatory Proteins; Autophagy; Blotting, Western; Cholesterol, Dietary; Diet, High-Fat; Disease Models, Animal; Lysosomal-Associated Membrane Protein 2; Male; Microtubule-Associated Proteins; Myocardial Ischemia; Myocardium; Phosphorylation; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Swine; Swine, Miniature; Time Factors; TOR Serine-Threonine Kinases | 2014 |
Design, synthesis and biological evaluation of imine resveratrol derivatives as multi-targeted agents against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cell Line, Tumor; Copper; Humans; Neuroprotective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner.
Topics: Animals; Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Cellular Senescence; Female; G1 Phase; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2013 |
Resveratrol attenuates CoCl2-induced cochlear hair cell damage through upregulation of Sirtuin1 and NF-κB deacetylation.
Topics: Acetylation; Animals; Cell Death; Cobalt; Hair Cells, Auditory; NF-kappa B; Rats, Wistar; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Up-Regulation | 2013 |
Resveratrol attenuates early brain injury after subarachnoid hemorrhage through inhibition of NF-κB-dependent inflammatory/MMP-9 pathway.
Topics: Analysis of Variance; Animals; Antioxidants; Brain Injuries; Disease Models, Animal; Matrix Metalloproteinase 9; Neoplasm Proteins; Neurologic Examination; NF-kappa B; Nucleocytoplasmic Transport Proteins; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Subarachnoid Hemorrhage | 2014 |
Resveratrol-loaded polymeric nanoparticles: validation of an HPLC-PDA method to determine the drug entrapment and evaluation of its antioxidant activity.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Drug Compounding; Drug Evaluation; Free Radical Scavengers; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Resveratrol; Stilbenes | 2013 |
Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability.
Topics: Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; HEK293 Cells; Humans; Ion Transport; Nasal Mucosa; Paranasal Sinuses; Probability; Resveratrol; RNA, Messenger; Stilbenes | 2013 |
The effect of di-n-butyl phthalate on testis and the potential protective effects of resveratrol.
Topics: Animals; Dibutyl Phthalate; DNA Nucleotidylexotransferase; Dose-Response Relationship, Drug; Immunohistochemistry; In Situ Nick-End Labeling; Male; Protective Agents; Rats; Rats, Wistar; Resveratrol; Seminiferous Tubules; Stilbenes; Testis | 2016 |
Design, synthesis and cytotoxic evaluation of o-carboxamido stilbene analogues.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; HT29 Cells; Humans; MCF-7 Cells; Resveratrol; Stilbenes | 2013 |
Resveratrol attenuates left ventricular remodeling in old rats with COPD induced by cigarette smoke exposure and LPS instillation.
Topics: Animals; Apoptosis; Emphysema; Lipopolysaccharides; Male; Malondialdehyde; Myocardium; Myocytes, Cardiac; Nicotiana; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Smoke; Smoking; Stilbenes; Superoxide Dismutase; Ventricular Function, Left; Ventricular Remodeling | 2013 |
Anticancer effects of thymoquinone, caffeic acid phenethyl ester and resveratrol on A549 non-small cell lung cancer cells exposed to benzo(a)pyrene.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Benzoquinones; Caffeic Acids; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cytokines; Glutathione; Humans; Lung Neoplasms; Malondialdehyde; NF-kappa B; Nitric Oxide; Phenylethyl Alcohol; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2013 |
Sirtuin1 and autophagy protect cells from fluoride-induced cell stress.
Topics: Ameloblasts; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Blotting, Western; Cariostatic Agents; Cell Line; Cell Proliferation; Cell Survival; Dental Enamel; Dose-Response Relationship, Drug; Fluorides; Gene Expression; Mice; Microtubule-Associated Proteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Sodium Fluoride; Stilbenes | 2014 |
Phytoestrogens induce apoptosis through a mitochondria/caspase pathway in human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Caspase 3; Cell Proliferation; Estradiol; Fas Ligand Protein; Female; Genistein; Humans; MCF-7 Cells; Mitochondria; Phosphatidylinositol 3-Kinases; Phytoestrogens; Proto-Oncogene Proteins c-akt; Quercetin; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cells, Cultured; Drug Synergism; Humans; Lymphangioleiomyomatosis; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2014 |
Resveratrol treatment during goat oocytes maturation enhances developmental competence of parthenogenetic and hand-made cloned blastocysts by modulating intracellular glutathione level and embryonic gene expression.
Topics: Animals; Apoptosis; Blastocyst; Case-Control Studies; Cloning, Organism; Cumulus Cells; Dose-Response Relationship, Drug; Embryo Culture Techniques; Female; Gene Expression Regulation, Developmental; Glutathione; Goats; In Vitro Oocyte Maturation Techniques; Oocytes; Parthenogenesis; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Unsuspected pyocyanin effect in yeast under anaerobiosis.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Anaerobiosis; Antioxidants; Ascorbic Acid; Candida albicans; DNA, Fungal; Drug Resistance, Multiple, Fungal; Fermentation; Intercalating Agents; Mitochondria; Oxidative Stress; Pyocyanine; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2014 |
Aerobic oxidative coupling of resveratrol and its analogues by visible light using mesoporous graphitic carbon nitride (mpg-C(3)N(4)) as a bioinspired catalyst.
Topics: Benzofurans; Catalysis; Dimerization; Light; Nitriles; Oxidative Coupling; Porosity; Resorcinols; Resveratrol; Stilbenes | 2014 |
The effects of resveratrol on flap survival in diabetic rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Ischemia; Necrosis; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Surgical Flaps; Wound Healing | 2014 |
Resveratrol protects RPE cells from sodium iodate by modulating PPARα and PPARδ.
Topics: Angiogenesis Inhibitors; Antioxidants; Cells, Cultured; Cytoprotection; Gene Expression Regulation; Humans; Iodates; Macular Degeneration; PPAR alpha; PPAR delta; Resveratrol; RNA; Stilbenes | 2014 |
Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.
Topics: Angiogenesis Modulating Agents; Angiopoietin-2; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Male; Mice; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Resveratrol; Sirtuin 1; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Resveratrol and piceid metabolites and their fat-reduction effects in zebrafish larvae.
Topics: Animals; Chromatography, High Pressure Liquid; Fluorescent Dyes; Glucosides; Larva; Mass Spectrometry; Oxazines; Resveratrol; Stilbenes; Zebrafish | 2014 |
Beneficial effect of resveratrol on bovine oocyte maturation and subsequent embryonic development after in vitro fertilization.
Topics: Animals; Cattle; Dose-Response Relationship, Drug; Embryonic Development; Female; Fertilization in Vitro; Oocytes; Pregnancy; Prospective Studies; Resveratrol; Stilbenes; Treatment Outcome | 2014 |
Resveratrol-mediated reduction of collagen by inhibiting proliferation and producing apoptosis in human hypertrophic scar fibroblasts.
Topics: Apoptosis; Cell Cycle; Cell Proliferation; Cicatrix, Hypertrophic; Collagen Type I; Collagen Type III; Dose-Response Relationship, Drug; Female; Fibroblasts; Gene Expression Regulation; Humans; Hydroxyproline; Resveratrol; RNA, Messenger; Stilbenes; Young Adult | 2013 |
Resveratrol inhibits proliferation of hypoxic choroidal vascular endothelial cells.
Topics: Antioxidants; Caspase 3; Cell Hypoxia; Cell Line; Cell Proliferation; Cell Survival; Choroid; Cobalt; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinase 8; Resveratrol; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Resveratrol suppresses inflammatory responses in endometrial stromal cells derived from endometriosis: a possible role of the sirtuin 1 pathway.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Cells, Cultured; Endometriosis; Endometrium; Enzyme Activators; Enzyme Inhibitors; Female; Humans; Interleukin-8; Naphthols; Ovarian Diseases; Ovary; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Stromal Cells | 2014 |
A characterization study of resveratrol/sulfobutyl ether-β-cyclodextrin inclusion complex and in vitro anticancer activity.
Topics: Antineoplastic Agents; beta-Cyclodextrins; Cell Death; Humans; MCF-7 Cells; Resveratrol; Solubility; Solutions; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2014 |
Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase.
Topics: Aging; Animals; Cerebrum; Dementia, Vascular; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Microcirculation; NADPH Oxidases; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents | 2014 |
The resveratrol tetramer (-)-hopeaphenol inhibits type III secretion in the gram-negative pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa.
Topics: Bacterial Proteins; Bacterial Secretion Systems; Blotting, Western; Chlamydia trachomatis; HeLa Cells; Humans; Phenols; Protein Transport; Pseudomonas aeruginosa; Resveratrol; Stilbenes; Virulence; Yersinia pseudotuberculosis | 2013 |
Targeting host nucleotide biosynthesis with resveratrol inhibits emtricitabine-resistant HIV-1.
Topics: Anti-HIV Agents; Cells, Cultured; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Enzyme-Linked Immunosorbent Assay; HIV Core Protein p24; HIV Reverse Transcriptase; HIV-1; Humans; Lymphocytes; Mutation, Missense; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Virus Replication | 2014 |
An improved highly sensitive method to determine low oxyresveratrol concentrations in rat plasma and its pharmacokinetic application.
Topics: Animals; Chromatography, Liquid; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Sensitivity and Specificity; Stilbenes | 2014 |
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts.
Topics: Animals; Cell Differentiation; Cell Line, Transformed; Cell Proliferation; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Hypertrophy; Mice; Muscle Development; Myoblasts; Resveratrol; Stilbenes | 2013 |
Resveratrol induces apoptosis and autophagy in T-cell acute lymphoblastic leukemia cells by inhibiting Akt/mTOR and activating p38-MAPK.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Humans; p38 Mitogen-Activated Protein Kinases; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; T-Lymphocytes; TOR Serine-Threonine Kinases | 2013 |
Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: inhibition of the MAP kinase signaling.
Topics: 3T3 Cells; Animals; Dinoprost; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Osteoprotegerin; Phosphorylation; Protein Kinase Inhibitors; Resveratrol; RNA, Messenger; Stilbenes | 2014 |
Comparison of natural estrogens and synthetic derivative on genioglossus function and estrogen receptors expression in rats with chronic intermittent hypoxia.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Estradiol; Estradiol Congeners; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Genistein; Hypoxia; Indenes; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Myoblasts, Skeletal; Rats; Rats, Sprague-Dawley; Resorcinols; Resveratrol; Sleep Apnea, Obstructive; Stilbenes; Tongue | 2014 |
Defining the action spectrum of potential PGC-1α activators on a mitochondrial and cellular level in vivo.
Topics: Aminoimidazole Carboxamide; Animals; Bezafibrate; HeLa Cells; Humans; Metformin; Mice; Mitochondrial Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Ribonucleotides; Rosiglitazone; Signal Transduction; Stilbenes; Thiazolidinediones; Transcription Factors | 2014 |
Herb-drug interactions: challenges and opportunities for improved predictions.
Topics: Animals; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Government Regulation; Herb-Drug Interactions; Humans; Legislation, Drug; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Plant Preparations; Resveratrol; Silybin; Silybum marianum; Silymarin; Stilbenes | 2014 |
Inhibitory effects of grape skin extract and resveratrol on fatty acid synthase.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Survival; Enzyme Inhibitors; Fatty Acid Synthases; Lipids; Lipogenesis; Mice; Oxidoreductases; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2013 |
Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; bcl-2-Associated X Protein; Caspase 3; Male; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Organ Size; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2013 |
Sirt1 activation ameliorates renal fibrosis by inhibiting the TGF-β/Smad3 pathway.
Topics: Animals; Fibrosis; Humans; Mice; Rats; Renal Insufficiency, Chronic; Resveratrol; Signal Transduction; Sirtuin 1; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1 | 2014 |
Comparison of the antidepressive effects of trans-resveratrol and 5-methoxy-7H-dibenzo[de,h]quinolin-7-one.
Topics: Animals; Antidepressive Agents; Aporphines; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Resveratrol; Stilbenes; Swimming | 2014 |
The stilbenes resveratrol, pterostilbene and piceid affect growth and stress resistance in mammalian cells via a mechanism requiring estrogen receptor beta and the induction of Mn-superoxide dismutase.
Topics: Animals; Antioxidants; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogen Receptor beta; Glucosides; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Oxidative Stress; Resveratrol; Stilbenes; Structure-Activity Relationship; Superoxide Dismutase | 2014 |
Enzymatic transformation of polydatin to resveratrol by piceid-β-D-glucosidase from Aspergillus oryzae.
Topics: Aspergillus oryzae; beta-Glucosidase; Biotechnology; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fallopia japonica; Glucosides; Hydrogen-Ion Concentration; Resveratrol; Stilbenes; Temperature; Time Factors | 2014 |
Optimized ultrasound-assisted extraction of phenolic compounds from Polygonum cuspidatum.
Topics: Emodin; Fallopia japonica; Glucosides; Phenols; Plant Extracts; Resveratrol; Solvents; Sound; Stilbenes; Temperature | 2013 |
Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling.
Topics: Anticarcinogenic Agents; Blotting, Western; Cells, Cultured; Cytochrome-c Oxidase Deficiency; Electron Transport; Electron Transport Complex I; Electron Transport Complex IV; ERRalpha Estrogen-Related Receptor; Estrogen Receptor alpha; Fibroblasts; Humans; Lactates; Mitochondrial Membranes; Oxygen Consumption; Pyruvates; Receptors, Estrogen; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Skin; Stilbenes | 2014 |
Topoisomerase II-targeting properties of a grapevine-shoot extract and resveratrol oligomers.
Topics: Antigens, Neoplasm; Biocatalysis; Cell Line, Tumor; Comet Assay; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Enzyme Inhibitors; Humans; Plant Extracts; Plant Shoots; Resveratrol; Stilbenes; Vitis | 2014 |
Resveratrol induced structural and biochemical alterations in the tegument of Raillietina echinobothrida.
Topics: Animals; Anthelmintics; Cestoda; Enzyme Inhibitors; Resveratrol; Stilbenes | 2014 |
An in vitro study of neuroprotective properties of traditional Chinese herbal medicines thought to promote healthy ageing and longevity.
Topics: Analysis of Variance; Animals; Antioxidants; Apoptosis; Biphenyl Compounds; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Mice; Mice, Inbred BALB C; Neurons; Neuroprotective Agents; Picrates; Resveratrol; Staurosporine; Stilbenes; Toxicity Tests | 2013 |
[Resveratrol reduces inflammatory cytokines via inhibiting nuclear factor-κB and mitogen-activated protein kinase signal pathway in a rabbit atherosclerosis model].
Topics: Animals; Atherosclerosis; Disease Models, Animal; Interleukin-1beta; Interleukin-6; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Rabbits; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2013 |
Enhancement in efferocytosis of oxidized low-density lipoprotein-induced apoptotic RAW264.7 cells through Sirt1-mediated autophagy.
Topics: Apoptosis; Atherosclerosis; Autophagy; Cell Line; Gene Expression Regulation; Humans; Lipoproteins, LDL; Molecular Targeted Therapy; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Potentiation of mutant CFTR Cl- channel currents by the naturally occurring stilbene compound resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cystic Fibrosis Transmembrane Conductance Regulator; Iodides; Mutation; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Submucous Plexus | 2013 |
In vitro drug release and ex vivo percutaneous absorption of resveratrol cream using HPLC with zirconized silica stationary phase.
Topics: Administration, Cutaneous; Adult; Chromatography, High Pressure Liquid; Female; Humans; Permeability; Resveratrol; Silicon Dioxide; Skin Absorption; Skin Cream; Stilbenes | 2014 |
Effects of resveratrol on oral squamous cell carcinoma (OSCC) cells in vitro.
Topics: Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colorimetry; Humans; Mouth Neoplasms; Neoplasm Invasiveness; Resveratrol; Stilbenes | 2014 |
The effect of resveratrol on contractility of non-pregnant rat uterus: the contribution of K(+) channels.
Topics: 4-Aminopyridine; Animals; Benzimidazoles; Female; Glyburide; Isometric Contraction; Muscle, Smooth; Oxytocin; Peptides; Pinacidil; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tetraethylammonium; Uterus | 2013 |
Resveratrol improves the mitochondrial function and fertilization outcome of bovine oocytes.
Topics: Animals; Cattle; DNA, Mitochondrial; Female; Fertilization in Vitro; Gene Dosage; Membrane Potential, Mitochondrial; Mitochondria; Oocytes; Resveratrol; Sirtuin 1; Sperm-Ovum Interactions; Stilbenes; Up-Regulation | 2014 |
The effects of resveratrol on chronic constriction injury of sciatic nerve in rats.
Topics: Animals; Antioxidants; Chronic Disease; Constriction, Pathologic; Immunohistochemistry; Insulin-Like Growth Factor I; Male; Motor Activity; Neuroprotective Agents; Peripheral Nerve Injuries; Rats, Wistar; Resveratrol; Sciatic Nerve; Stilbenes | 2014 |
Resveratrol restores sirtuin 1 (SIRT1) activity and pyruvate dehydrogenase kinase 1 (PDK1) expression after hemorrhagic injury in a rat model.
Topics: Animals; Disease Models, Animal; Gene Expression Regulation; Hemorrhage; Male; Mitochondria; Platelet Aggregation Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Effects of hydroxylated resveratrol analogs on oxidative stress and cancer cells death in human acute T cell leukemia cell line: prooxidative potential of hydroxylated resveratrol analogs.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Stability; Humans; Hydroxylation; Jurkat Cells; Molecular Structure; Oxidation-Reduction; Oxidative Stress; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes | 2014 |
AMP-activated protein kinase α2 and E2F1 transcription factor mediate doxorubicin-induced cytotoxicity by forming a positive signal loop in mouse embryonic fibroblasts and non-carcinoma cells.
Topics: AMP-Activated Protein Kinases; Animals; Cell Death; Cell Line; Cytoprotection; DNA Damage; Doxorubicin; E2F1 Transcription Factor; Embryo, Mammalian; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Mice; Models, Biological; Phosphorylation; Protein Binding; Protein Stability; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Polycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering.
Topics: Bone Regeneration; Cells, Cultured; Drug Implants; Humans; Mesenchymal Stem Cells; Nanoparticles; Osteogenesis; Polyesters; Porosity; Resveratrol; Stilbenes; Tissue Engineering; Tissue Scaffolds | 2014 |
Evolution of human longevity uncoupled from caloric restriction mechanisms.
Topics: Adult; Aging; Animals; Brain; Caloric Restriction; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation; Humans; Longevity; Macaca mulatta; Male; Mice; Pan troglodytes; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases | 2014 |
SIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survival.
Topics: Acetylation; Adult; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Dinoprost; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Keratinocytes; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; Middle Aged; Mitochondria; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Sirtuin 1; Skin; Stilbenes; Superoxides; Vitiligo | 2014 |
Oxidative stress mediated by NMDA, AMPA/KA channels in acute hippocampal slices: neuroprotective effect of resveratrol.
Topics: Animals; Antioxidants; Astrocytes; Gene Expression Regulation; Glutamate-Ammonia Ligase; Glutamic Acid; Hippocampus; Lipid Peroxidation; Male; Mitochondria; Mitophagy; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Resveratrol; Sodium-Potassium-Exchanging ATPase; Stilbenes | 2014 |
Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Enzyme Inhibitors; Ferric Compounds; Humans; Imaging, Three-Dimensional; Metal Nanoparticles; Mice; Mice, Transgenic; Microglia; Mutation; Neuroprotective Agents; NF-kappa B; Plaque, Amyloid; Presenilin-1; Resveratrol; Stilbenes | 2014 |
The effect of resveratrol on the expression of AdipoR1 in kidneys of diabetic nephropathy.
Topics: Animals; Body Weight; Collagen Type IV; Diabetic Nephropathies; Disease Models, Animal; Fibronectins; Forkhead Transcription Factors; Gene Expression Regulation; Glucose; Kidney; Lipid Peroxidation; Male; Mesangial Cells; Nerve Tissue Proteins; Oxidative Stress; Rats; Receptors, Adiponectin; Resveratrol; Stilbenes | 2014 |
Effects of resveratrol, oxyresveratrol, and their acetylated derivatives on cellular melanogenesis.
Topics: Acetylation; Animals; Cell Line, Tumor; Cell Survival; HEK293 Cells; Humans; Hyperpigmentation; Melanins; Melanoma, Experimental; Mice; Models, Biological; Monophenol Monooxygenase; Plant Extracts; Resveratrol; Skin Physiological Phenomena; Skin Pigmentation; Stilbenes; Ultraviolet Rays | 2014 |
Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; Microglia; Mitochondria; Motor Activity; Motor Neurons; Neuroprotective Agents; Resveratrol; Sirtuins; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2014 |
Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.
Topics: Animals; Crosses, Genetic; Disease Models, Animal; Endothelial Cells; Gene Expression; Heterocyclic Compounds, 4 or More Rings; Humans; Integrases; Macrophages; Mice; Neovascularization, Pathologic; Nerve Degeneration; Nestin; Neurons; Oxygen; Receptor, TIE-2; Resveratrol; Retina; Retinal Degeneration; Sirtuin 1; Stilbenes | 2014 |
Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK.
Topics: AMP-Activated Protein Kinases; Cell Differentiation; Contractile Proteins; Dose-Response Relationship, Drug; Humans; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Multiprotein Complexes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases | 2014 |
[Comparative and correlational studies on contents of stilbenes in different portions of mulberry].
Topics: Chromatography, High Pressure Liquid; Disaccharides; Morus; Plant Roots; Resveratrol; Stilbenes | 2013 |
Resveratrol protects SR-B1 levels in keratinocytes exposed to cigarette smoke.
Topics: Aldehydes; Antioxidants; Cell Line; Cholesterol; Humans; Keratinocytes; Oxidative Stress; Resveratrol; Scavenger Receptors, Class B; Skin; Smoking; Stilbenes | 2014 |
Structural characteristics that determine the inhibitory role of phenolic compounds on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) formation.
Topics: Catechin; Imidazoles; Lipids; Maillard Reaction; Quercetin; Resveratrol; Stilbenes | 2014 |
Characterization of cDNA encoding resveratrol synthase and accumulation of resveratrol in tartary buckwheat.
Topics: Acyltransferases; DNA, Complementary; DNA, Plant; Fagopyrum; Resveratrol; Stilbenes | 2013 |
Resveratrol induces acute endothelium-dependent renal vasodilation mediated through nitric oxide and reactive oxygen species scavenging.
Topics: Acute Disease; Animals; Disease Models, Animal; Kidney; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Circulation; Resveratrol; Stilbenes; Vascular Resistance; Vasodilation | 2014 |
Antiobesity and vasoprotective effects of resveratrol in apoE-deficient mice.
Topics: Animals; Anti-Obesity Agents; Anticholesteremic Agents; Aorta; Apolipoproteins E; Arteriosclerosis; Diet, Atherogenic; Humans; Lovastatin; Male; Mice; Mice, Knockout; Obesity; Protective Agents; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits BMP-4-stimulated VEGF synthesis in osteoblasts: suppression of S6 kinase.
Topics: Animals; Bone Morphogenetic Protein 4; Cell Line; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Mice; Osteoblasts; Phosphorylation; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Smad Proteins; Stilbenes; Vascular Endothelial Growth Factor A | 2014 |
Protective effects of chronic resveratrol treatment on vascular inflammatory injury in steptozotocin-induced type 2 diabetic rats: role of NF-kappa B signaling.
Topics: Animals; Aorta, Thoracic; Capillary Permeability; Carotid Arteries; Carotid Artery Injuries; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Endothelial Cells; Humans; Hypoglycemic Agents; Insulin; Interleukin-1beta; Interleukin-6; Lipids; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2013 |
CLOCK/BMAL1 regulates circadian change of mouse hepatic insulin sensitivity by SIRT1.
Topics: Animals; Antioxidants; ARNTL Transcription Factors; Circadian Rhythm; CLOCK Proteins; Darkness; Down-Regulation; Hepatocytes; Insulin Resistance; Liver; Mice; Mice, Knockout; Promoter Regions, Genetic; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue.
Topics: Animals; Azacitidine; Breast; Breast Neoplasms; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Estrogens; Female; MicroRNAs; Rats; Rats, Inbred ACI; Resveratrol; Stilbenes | 2014 |
Resveratrol Enhances Chemosensitivity in Mouse Melanoma Model Through Connexin 43 Upregulation.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cisplatin; Connexin 43; Dose-Response Relationship, Drug; Gap Junctions; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2015 |
Cardiovascular effects of resveratrol.
Topics: Antioxidants; Cardiovascular System; Humans; Resveratrol; Stilbenes | 2013 |
Resveratrol partially prevents rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through induction of heme oxygenase-1 dependent autophagy.
Topics: Animals; Apoptosis; Autophagy; Cell Line, Tumor; Dopaminergic Neurons; Heme Oxygenase-1; Humans; Male; Mitochondria; Neuroprotective Agents; Oxidation-Reduction; Rats; Rats, Inbred Lew; Resveratrol; Rotenone; Stilbenes | 2014 |
Resveratrol oligomers inhibit biofilm formation of Escherichia coli O157:H7 and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Benzofurans; Biofilms; Escherichia coli O157; Molecular Structure; Phenols; Pseudomonas aeruginosa; Resveratrol; Stilbenes | 2014 |
Improved oral delivery of resveratrol using proliposomal formulation: investigation of various factors contributing to prolonged absorption of unmetabolized resveratrol.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Intestinal Absorption; Liposomes; Male; Particle Size; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes | 2014 |
Resveratrol appears to protect against oxidative stress and steroidogenesis collapse in mice fed high-calorie and high-cholesterol diet.
Topics: Animals; Antioxidants; Cholesterol; Diet; Energy Intake; Glutathione Peroxidase; Leydig Cells; Male; Mice; Obesity; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Phosphoproteins; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase; Testis; Testosterone | 2015 |
Dietary resveratrol supplementation normalizes gene expression in the hippocampus of streptozotocin-induced diabetic C57Bl/6 mice.
Topics: Animals; Blood Glucose; Body Weight; Diet; Gene Expression; Hippocampus; Male; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Streptozocin | 2014 |
Resveratrol attenuates hypoxic injury in a primary hepatocyte model of hemorrhagic shock and resuscitation.
Topics: Animals; Blotting, Western; Cell Death; Cell Hypoxia; Cell Survival; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hepatocytes; Immunohistochemistry; In Vitro Techniques; Interleukin-6; Male; Mitochondria, Liver; NF-kappa B; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Resuscitation; Resveratrol; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
[Effects of resveratrol on morphology and oxidative stress of brain tissues in aging mice].
Topics: Aging; Animals; Antioxidants; Brain; Galactose; Male; Mice; Oxidative Stress; Protective Agents; Resveratrol; Stilbenes | 2013 |
Effects of resveratrol and irradiation upon oral squamous cell carcinoma cells.
Topics: Anticarcinogenic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Mouth Neoplasms; Radiotherapy Dosage; Resveratrol; S Phase; Stilbenes; Time Factors | 2014 |
Bioaccumulation of resveratrol metabolites in myocardial tissue is dose-time dependent and related to cardiac hemodynamics in diabetic rats.
Topics: Animals; Biotransformation; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Glucuronides; Heart Diseases; Hemodynamics; Male; Myocardium; Rats, Wistar; Resveratrol; Stilbenes; Sulfates; Time Factors | 2014 |
Resveratrol increases antioxidant defenses and decreases proinflammatory cytokines in hippocampal astrocyte cultures from newborn, adult and aged Wistar rats.
Topics: Aging; Animals; Animals, Newborn; Antioxidants; Astrocytes; Cells, Cultured; Cytokines; Hippocampus; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers; Caco-2 Cells; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Energy Metabolism; Glucose; HCT116 Cells; Humans; Resveratrol; Signal Transduction; Stilbenes; Thiazolidinediones | 2014 |
Resveratrol ameliorates diabetic vascular inflammation and macrophage infiltration in db/db mice by inhibiting the NF-κB pathway.
Topics: Animals; Antigens, Differentiation; Blood Glucose; Chemokine CCL2; Diabetes Complications; Diabetes Mellitus; Inflammation; Intercellular Adhesion Molecule-1; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Vascular Cell Adhesion Molecule-1 | 2014 |
Treatment of obesity with the resveratrol-enriched rice DJ-526.
Topics: Abdominal Fat; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Female; Lipids; Mice; Mice, Inbred C57BL; Obesity; Oryza; Plants, Genetically Modified; Resveratrol; Stilbenes | 2014 |
Resveratrol promotes endothelial cell wound healing under laminar shear stress through an estrogen receptor-α-dependent pathway.
Topics: Animals; Cardiovascular Agents; Carotid Arteries; Cell Proliferation; Endothelium, Vascular; Estrogen Receptor alpha; Extracellular Signal-Regulated MAP Kinases; Female; In Vitro Techniques; Mice; Mice, Inbred Strains; Models, Animal; Nitric Oxide Synthase Type III; Paclitaxel; Regional Blood Flow; Resveratrol; Shear Strength; Signal Transduction; Stilbenes; Stress, Mechanical; Wound Healing | 2014 |
Primary cilia mediate sonic hedgehog signaling to regulate neuronal-like differentiation of bone mesenchymal stem cells for resveratrol induction in vitro.
Topics: Animals; Antioxidants; Bromodeoxyuridine; Cell Differentiation; Cells, Cultured; Cilia; Female; Gene Expression Regulation; Hedgehog Proteins; Male; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Resveratrol inhibits cisplatin-induced epithelial-to-mesenchymal transition in ovarian cancer cell lines.
Topics: Analysis of Variance; Blotting, Western; Cell Death; Cell Line, Tumor; Cisplatin; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Humans; Ovarian Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Snail Family Transcription Factors; Stilbenes; Transcription Factors | 2014 |
Improved stability of trans-resveratrol in aqueous solutions by carboxymethylated (1,3/1,6)-β-D-glucan.
Topics: beta-Glucans; Chemistry, Pharmaceutical; Drug Stability; Resveratrol; Solubility; Stilbenes | 2014 |
Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Death; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Epithelial Cells; Female; Flap Endonucleases; Humans; Mammary Glands, Human; Mice; Mice, Inbred BALB C; Proliferating Cell Nuclear Antigen; Resveratrol; RNA Interference; Signal Transduction; Smoke; Smoking; Stilbenes; Time Factors; Transfection; Up-Regulation; Xenograft Model Antitumor Assays | 2014 |
Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Bone Morphogenetic Protein 7; Diet; Energy Metabolism; Ion Channels; Male; Mice; Mitochondrial Proteins; PTEN Phosphohydrolase; Resveratrol; Sirtuin 1; Stilbenes; Thermogenesis; Uncoupling Protein 1 | 2014 |
Resveratrol and vitamin E rescue valproic acid-induced teratogenicity: the mechanism of action.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Chick Embryo; Glutathione; Reactive Oxygen Species; Resveratrol; Stilbenes; Teratogenesis; Valproic Acid; Vitamin E | 2014 |
Disrupting androgen production of Leydig cells by resveratrol via direct inhibition of human and rat 3β-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Endocrine Disruptors; Enzyme Inhibitors; Humans; Leydig Cells; Luteinizing Hormone; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Testosterone | 2014 |
Protective effect of resveratrol on biomarkers of oxidative stress induced by iron/ascorbate in mouse spermatozoa.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Female; Glutathione Peroxidase; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Spermatozoa; Stilbenes; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2014 |
Resveratrol- and melatonin-abated ovariectomy and fructose diet-induced obesity and metabolic alterations in female rats.
Topics: Administration, Oral; Animals; Antioxidants; Diabetes Mellitus; Diet; Disease Models, Animal; Female; Fructose; Melatonin; Obesity; Ovariectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Resveratrol supplementation reduces aortic atherosclerosis and calcification and attenuates loss of aerobic capacity in a mouse model of uremia.
Topics: Animals; Aorta; Calcinosis; Coronary Artery Disease; Dietary Supplements; Disease Models, Animal; Female; Humans; Mice; Oxygen; Resveratrol; Stilbenes; Uremia | 2014 |
Resveratrol inhibits the TRIF-dependent pathway by upregulating sterile alpha and armadillo motif protein, contributing to anti-inflammatory effects after respiratory syncytial virus infection.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Armadillo Domain Proteins; Cytoskeletal Proteins; Down-Regulation; Female; Humans; Lung; Mice; Mice, Inbred BALB C; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2014 |
Understanding the anti-kindling role and its mechanism of Resveratrol in Pentylenetetrazole induced-kindling in a rat model.
Topics: Animals; Anticonvulsants; Antioxidants; Caspase 3; Convulsants; Hippocampus; Kindling, Neurologic; Lipid Peroxidation; Male; Oxidative Stress; Pentylenetetrazole; Phosphopyruvate Hydratase; Rats; Resveratrol; Seizures; Stilbenes | 2014 |
Resveratrol does not increase body fat loss induced by energy restriction.
Topics: Adipose Tissue; Animals; DNA Primers; Male; Rats; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2014 |
Amelioration of behavioural, biochemical, and neurophysiological deficits by combination of monosodium glutamate with resveratrol/alpha-lipoic acid/coenzyme Q10 in rat model of cisplatin-induced peripheral neuropathy.
Topics: Animals; Behavior, Animal; Catalase; Disease Models, Animal; Drug Therapy, Combination; Glutathione; Lipid Peroxidation; Neural Conduction; Neuroprotective Agents; Peripheral Nervous System Diseases; Psychomotor Performance; Rats; Resveratrol; Sciatic Neuropathy; Sodium Glutamate; Stilbenes; Thioctic Acid; Ubiquinone | 2013 |
Inhibition of NOX/VPO1 pathway and inflammatory reaction by trimethoxystilbene in prevention of cardiovascular remodeling in hypoxia-induced pulmonary hypertensive rats.
Topics: Animals; Hemeproteins; Hypertension, Pulmonary; Hypoxia; Inflammation; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Peroxidases; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Ventricular Remodeling | 2014 |
Resveratrol reverses cadmium chloride-induced testicular damage and subfertility by downregulating p53 and Bax and upregulating gonadotropins and Bcl-2 gene expression.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Cadmium Chloride; Drug Interactions; Follicle Stimulating Hormone; Gene Expression Regulation; Gonadotropins; Histocytochemistry; Infertility, Male; Luteinizing Hormone; Male; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Superoxide Dismutase; Testis; Testosterone; Thiobarbituric Acid Reactive Substances; Tumor Suppressor Protein p53 | 2014 |
Pharmacokinetics and safety of resveratrol derivatives in humans after oral administration of melinjo (Gnetum gnemon L.) seed extract powder.
Topics: Administration, Oral; Adult; Female; Gnetum; Healthy Volunteers; Humans; Male; Plant Extracts; Powders; Resveratrol; Seeds; Stilbenes; Young Adult | 2014 |
Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Cell Line, Tumor; Drug Synergism; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Oxides; Resveratrol; Stilbenes | 2014 |
Effects of resveratrol on the expression and DNA methylation of cytokine genes in diabetic rat aortas.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Cytokines; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Angiopathies; DNA Methylation; Gene Expression Regulation; Humans; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Th1-Th2 Balance | 2014 |
Co-administration of resveratrol and lipoic acid, or their synthetic combination, enhances neuroprotection in a rat model of ischemia/reperfusion.
Topics: Animals; Antioxidants; Brain Ischemia; Disease Models, Animal; Humans; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Stroke; Thioctic Acid | 2014 |
Pharmacological AMP kinase activators target the nucleolar organization and control cell proliferation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Line; Cell Nucleolus; Cell Proliferation; Chromosomal Proteins, Non-Histone; Humans; Nuclear Proteins; Nucleolin; Nucleolus Organizer Region; Nucleophosmin; Phenformin; Phosphoproteins; Resveratrol; Ribonucleotides; Ribosomes; RNA-Binding Proteins; Stilbenes | 2014 |
Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages.
Topics: Alcoholic Beverages; Animals; Antioxidants; Central Nervous System Depressants; Constitutive Androstane Receptor; Ellagic Acid; Ethanol; Fatty Liver, Alcoholic; Female; Gene Ontology; Liver; Metabolic Networks and Pathways; Mice; Mice, Inbred C3H; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Polyphenols; Receptors, Cytoplasmic and Nuclear; Resveratrol; Stilbenes; Transcriptome | 2014 |
Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).
Topics: Animals; Cell Line; Gene Expression Regulation; Humans; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Protein Transport; Proteolysis; Resveratrol; Sirtuin 1; Stilbenes; Symporters | 2014 |
Kir6.2-containing ATP-sensitive K(+) channel is required for cardioprotection of resveratrol in mice.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; KATP Channels; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocytes, Cardiac; Potassium Channels, Inwardly Rectifying; Resveratrol; Stilbenes | 2014 |
Preharvest methyl jasmonate and postharvest UVC treatments: increasing stilbenes in wine.
Topics: Acetates; Anthocyanins; Color; Cyclopentanes; Fruit; Humans; Odorants; Oxylipins; Plant Growth Regulators; Resveratrol; Stilbenes; Tannins; Taste; Ultraviolet Rays; Vitis; Wine | 2014 |
Autophagy induced by resveratrol suppresses α-MSH-induced melanogenesis.
Topics: alpha-MSH; Antineoplastic Agents, Phytogenic; Autophagy; Autophagy-Related Protein 5; Cell Line, Tumor; Down-Regulation; Humans; Melanins; Melanocytes; Melanosomes; Microtubule-Associated Proteins; Monophenol Monooxygenase; Resveratrol; Stilbenes; Trypsin | 2014 |
[Protective effect of retrograde venous perfusion of cryogenic liquid via accessory hemiazygos vein and treated with resveratrol on spinal cord injury in swine].
Topics: Animals; Hypothermia, Induced; Male; Microtubule-Associated Proteins; Reperfusion Injury; Resveratrol; Spinal Cord; Spinal Cord Injuries; Stilbenes; Swine | 2013 |
Total synthesis of resveratrol-based natural products using a palladium-catalyzed decarboxylative arylation and an oxidative Heck reaction.
Topics: Biological Products; Catalysis; Decarboxylation; Oxidation-Reduction; Palladium; Resveratrol; Stereoisomerism; Stilbenes | 2014 |
Inhibitory effects of stilbenes on the growth of three soybean pathogens in culture.
Topics: Ascomycota; Culture Media; Glycine max; Plant Diseases; Resveratrol; Rhizoctonia; Stilbenes | 2014 |
Resveratrol reverses the effects of chronic unpredictable mild stress on behavior, serum corticosterone levels and BDNF expression in rats.
Topics: Animals; Antioxidants; Body Weight; Brain-Derived Neurotrophic Factor; Corticosterone; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Food Deprivation; Food Preferences; Gene Expression Regulation; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Stress, Psychological; Swimming; Time Factors | 2014 |
Characterization and modulation of human mesenchymal stem cell stress pathway response following hypothermic storage.
Topics: Apoptosis; Blotting, Western; Cell Survival; Cinnamates; Cryopreservation; Cryoprotective Agents; Flow Cytometry; Humans; Mesenchymal Stem Cells; Necrosis; Osmoregulation; Resveratrol; Stilbenes; Stress, Physiological; Thiourea | 2014 |
Trans-resveratrol self-nano-emulsifying drug delivery system (SNEDDS) with enhanced bioavailability potential: optimization, pharmacokinetics and in situ single pass intestinal perfusion (SPIP) studies.
Topics: Animals; Antioxidants; Biological Availability; Drug Delivery Systems; Drug Liberation; Emulsions; Intestinal Absorption; Lipids; Male; Nanoparticles; Particle Size; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Surface-Active Agents | 2015 |
In-situ detection of resveratrol inhibition effect on epidermal growth factor receptor of living MCF-7 cells by Atomic Force Microscopy.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Survival; Epidermal Growth Factor; ErbB Receptors; Female; Humans; Immobilized Proteins; MCF-7 Cells; Microscopy, Atomic Force; Optical Imaging; Resveratrol; Stilbenes | 2014 |
Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention.
Topics: Adenomatous Polyposis Coli; Animals; Aspirin; Cell Death; Cell Line, Tumor; Epithelial Cells; Flow Cytometry; Image Processing, Computer-Assisted; In Situ Hybridization, Fluorescence; Mice; Mice, Inbred C57BL; Microscopy, Video; Resveratrol; Stilbenes; Tetraploidy | 2014 |
[Study of resveratrol suppressing TGF-beta1 induced transdifferentiation of podocytes].
Topics: Animals; Cell Transdifferentiation; Cells, Cultured; Kidney Tubules; Mice; Podocytes; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2013 |
Viniphenol A, a complex resveratrol hexamer from Vitis vinifera stalks: structural elucidation and protective effects against amyloid-β-induced toxicity in PC12 cells.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Catechin; Dioxanes; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; PC12 Cells; Rats; Resveratrol; Stilbenes; Vitis | 2014 |
Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis.
Topics: Androstenedione; Androsterone; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Simvastatin; Steroid 17-alpha-Hydroxylase; Stilbenes; Theca Cells; Time Factors | 2014 |
Resveratrol induces human K562 cell apoptosis, erythroid differentiation, and autophagy.
Topics: Anion Exchange Protein 1, Erythrocyte; Antigens, CD; Antineoplastic Agents; Apoptosis; Autophagy; Cell Differentiation; Cell Proliferation; Erythroid Cells; Glycophorins; Humans; K562 Cells; Receptors, Transferrin; Resveratrol; Stilbenes | 2014 |
Cytotoxic effects of Phytophenolics from Caesalpinia mimosoides Lamk on cervical carcinoma cell lines through an apoptotic pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caesalpinia; Caffeine; Caspase 3; Caspase 7; Cell Survival; Chlorocebus aethiops; Coumaric Acids; Enzyme Activation; Gallic Acid; HeLa Cells; Humans; Inhibitory Concentration 50; Phenols; Plant Extracts; Plant Leaves; Plant Shoots; Resveratrol; Stilbenes; Vanillic Acid; Vero Cells | 2014 |
Resveratrol improves bone repair by modulation of bone morphogenetic proteins and osteopontin gene expression in rats.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Dental Implants; Gene Expression; Implants, Experimental; Integrin-Binding Sialoprotein; Male; Osteopontin; Osteoprotegerin; RANK Ligand; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Tibia; Titanium; Up-Regulation; Wound Healing | 2014 |
Combination of low dose of the anti-adipogenic agents resveratrol and phenelzine in drinking water is not sufficient to prevent obesity in very-high-fat diet-fed mice.
Topics: Adipocytes; Adipogenesis; Animals; Blood Glucose; Body Composition; Diet, High-Fat; Dose-Response Relationship, Drug; Drinking Water; Glucose Tolerance Test; Lipogenesis; Male; Mice; Mice, Inbred C57BL; Obesity; Phenelzine; Resveratrol; Stilbenes; Weight Gain | 2014 |
Validating antimetastatic effects of natural products in an engineered microfluidic platform mimicking tumor microenvironment.
Topics: Antineoplastic Agents; Benzophenanthridines; Biological Products; Biomimetics; Cell Line, Tumor; Coculture Techniques; Drug Screening Assays, Antitumor; Endothelial Cells; Humans; Isoquinolines; Lab-On-A-Chip Devices; Microfluidics; Models, Biological; Resveratrol; Stilbenes; Tumor Microenvironment | 2014 |
Resveratrol prevents TNF-α-induced muscle atrophy via regulation of Akt/mTOR/FoxO1 signaling in C2C12 myotubes.
Topics: Animals; Cell Line; Forkhead Box Protein O1; Forkhead Transcription Factors; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; RNA, Small Interfering; Signal Transduction; SKP Cullin F-Box Protein Ligases; Stilbenes; TOR Serine-Threonine Kinases; Tripartite Motif Proteins; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases | 2014 |
The prosurvival role of autophagy in resveratrol-induced cytotoxicity in GH3 cells.
Topics: Animals; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Cell Survival; Enzyme Activation; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2014 |
Resveratrol induces apoptosis of bladder cancer cells via miR‑21 regulation of the Akt/Bcl‑2 signaling pathway.
Topics: Apoptosis; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes; Urinary Bladder Neoplasms | 2014 |
Resveratrol, an activator of SIRT1, upregulates AMPK and improves cardiac function in heart failure.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Cells, Cultured; Heart Failure; Male; Mice; Myocardial Infarction; Myocytes, Cardiac; Niacinamide; Rats; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation; Ventricular Function | 2014 |
Resveratrol decreases fructose-induced oxidative stress, mediated by NADPH oxidase via an AMPK-dependent mechanism.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Blood Pressure; Cerebellum; Fructose; Hypertension; Male; NADPH Oxidases; Nitric Oxide Synthase Type I; Nitrogen Oxides; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; Solitary Nucleus; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2014 |
Involvement of TACE in colon inflammation: a novel mechanism of regulation via SIRT-1 activation.
Topics: Acute Disease; ADAM Proteins; ADAM17 Protein; Animals; Colitis; Colon; Cytokines; Dextran Sulfate; Female; Inflammation; Kinetics; Mice; Mice, Inbred C57BL; Resveratrol; Sirtuin 1; Stilbenes; Time Factors; Tissue Inhibitor of Metalloproteinase-3 | 2014 |
The effects of resveratrol on tissue injury, oxidative damage, and pro-inflammatory cytokines in an experimental model of acute pancreatitis.
Topics: Acute Disease; Animals; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Inflammation Mediators; Male; Oxidative Stress; Pancreatitis; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
Synergistic effects of polyphenols and methylxanthines with Leucine on AMPK/Sirtuin-mediated metabolism in muscle cells and adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Caffeic Acids; Chlorogenic Acid; Ellagic Acid; Fatty Acids; Humans; Leucine; Mice; Muscle Cells; NAD; Oxidation-Reduction; Phosphodiesterase Inhibitors; Polyphenols; Protein Kinase Inhibitors; Resveratrol; Sirtuin 1; Stilbenes; Valerates; Xanthines | 2014 |
Effect of lipolysis on drug release from self-microemulsifying drug delivery systems (SMEDDS) with different core/shell drug location.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Emulsions; Hydrophobic and Hydrophilic Interactions; Hymecromone; Kinetics; Lipids; Lipolysis; Pancreatin; Resveratrol; Solubility; Spectrometry, Fluorescence; Stilbenes; Surface-Active Agents; Technology, Pharmaceutical | 2014 |
Sirtuin 1-mediated inhibition of p66shc expression alleviates liver ischemia/reperfusion injury.
Topics: Abietanes; Analysis of Variance; Animals; Caspases; Enzyme Inhibitors; Hep G2 Cells; Humans; In Situ Nick-End Labeling; Ischemia; Ischemic Preconditioning; Liver; Male; Niacinamide; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Sirtuin 1; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes; Superoxide Dismutase; Transaminases | 2014 |
Resveratrol attenuates morphine antinociceptive tolerance via SIRT1 regulation in the rat spinal cord.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Tolerance; Histones; Injections, Spinal; Male; Morphine; Narcotics; Nociception; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes | 2014 |
Simultaneous quantification of trans-resveratrol and its sulfate and glucuronide metabolites in rat tissues by stable isotope-dilution UPLC-MS/MS analysis.
Topics: Animals; Chromatography, High Pressure Liquid; Glucuronides; Isotopes; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfates; Tandem Mass Spectrometry | 2014 |
Construction of artificial biosynthetic pathways for resveratrol glucoside derivatives.
Topics: Antioxidants; Bacterial Proteins; Biosynthetic Pathways; Escherichia coli; Gene Order; Genetic Vectors; Glucosides; Resveratrol; Stilbenes | 2014 |
Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates.
Topics: Animals; Contraindications; Diet; Dietary Supplements; Female; Fetal Development; Fetus; Liver; Macaca; Pancreas; Placental Circulation; Pregnancy; Regional Blood Flow; Resveratrol; Stilbenes; Triglycerides; Uterus | 2014 |
Resveratrol inhibits oesophageal adenocarcinoma cell proliferation via AMP-activated protein kinase signaling.
Topics: Adenocarcinoma; AMP-Activated Protein Kinases; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p57; Esophageal Neoplasms; Humans; Proteasome Endopeptidase Complex; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; S-Phase Kinase-Associated Proteins; Signal Transduction; Stilbenes; Tumor Cells, Cultured; Ubiquitination | 2014 |
Resveratrol attenuates NF-κB-binding activity but not cytokine production in mechanically ventilated mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; DNA; Enzyme-Linked Immunosorbent Assay; Heart; Lung; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Respiration, Artificial; Resveratrol; Stilbenes | 2014 |
Novel resveratrol-based substrates for human hepatic, renal, and intestinal UDP-glucuronosyltransferases.
Topics: Chromatography, High Pressure Liquid; Glucuronosyltransferase; Humans; Intestines; Kidney; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microsomes; Resveratrol; Stilbenes; Substrate Specificity | 2014 |
Resveratrol triggers protective autophagy through the ceramide/Akt/mTOR pathway in melanoma B16 cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Death; Cell Line, Tumor; Ceramides; Gene Knockdown Techniques; Melanoma, Experimental; Mice; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2014 |
Effect of resveratrol on mitochondrial function: implications in parkin-associated familiar Parkinson's disease.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Cells, Cultured; Female; Fibroblasts; Genetic Predisposition to Disease; Humans; Middle Aged; Mitochondria; NAD; Oxidative Stress; Oxygen Consumption; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors; Ubiquitin-Protein Ligases | 2014 |
Efficient delivery and distribution in skin of chlorogenic acid and resveratrol induced by microemulsion using sucrose laurate.
Topics: Administration, Cutaneous; Animals; Chlorogenic Acid; Emulsions; Ethanol; Myristates; Polysorbates; Resveratrol; Skin Absorption; Stilbenes; Sucrose; Surface-Active Agents; Swine; Water | 2014 |
VaCPK20 gene overexpression significantly increased resveratrol content and expression of stilbene synthase genes in cell cultures of Vitis amurensis Rupr.
Topics: Acyltransferases; Cells, Cultured; Plant Proteins; Plants, Genetically Modified; Protein Kinases; Resveratrol; Stilbenes; Vitis | 2014 |
Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins.
Topics: Cell Differentiation; Cell Line; Chemokine CCL2; Foam Cells; Humans; Lipid Metabolism; Lipopolysaccharides; Lipoproteins, LDL; Macrophages; PPAR alpha; PPAR gamma; Resveratrol; Sirtuin 1; Stilbenes; Tetradecanoylphorbol Acetate | 2014 |
Short-term resveratrol exposure causes in vitro and in vivo growth inhibition and apoptosis of bladder cancer cells.
Topics: Active Transport, Cell Nucleus; Analysis of Variance; Animals; Apoptosis; Blotting, Western; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; DNA Primers; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Mice; Mice, Nude; Phosphorylation; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; S Phase Cell Cycle Checkpoints; STAT3 Transcription Factor; Stilbenes; Tyrphostins; Urinary Bladder Neoplasms | 2014 |
Resveratrol improves muscle function but not oxidative capacity in young mdx mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Inflammation; Male; Mice, Inbred mdx; Muscle, Skeletal; Myocardium; Organ Size; Oxidative Stress; Random Allocation; Resveratrol; Spleen; Stilbenes; Utrophin | 2014 |
Rapid and simultaneous in situ assessment of aflatoxins and stilbenes using silica plate imprinting mass spectrometry imaging.
Topics: Aflatoxins; Arachis; Food Contamination; Mass Spectrometry; Mycotoxins; Nuts; Phytoalexins; Resveratrol; Sesquiterpenes; Silicon Dioxide; Stilbenes | 2014 |
Amino acid-PEGylated resveratrol and its influence on solubility and the controlled release behavior.
Topics: Amino Acids; Biological Availability; Drug Design; Drug Liberation; Polyethylene Glycols; Prodrugs; Resveratrol; Solubility; Stilbenes | 2014 |
Resveratrol down-regulates a glutamate-induced tissue plasminogen activator via Erk and AMPK/mTOR pathways in rat primary cortical neurons.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Cerebral Cortex; Down-Regulation; Glutamic Acid; MAP Kinase Signaling System; Neurons; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tissue Plasminogen Activator; TOR Serine-Threonine Kinases | 2014 |
Inhibition potential of UDP-glucuronosyltransferases (Ugts) 1A isoforms by the analogue of resveratrol, bakuchiol.
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Indicators and Reagents; Isoenzymes; Kinetics; Phenols; Resveratrol; Stilbenes | 2014 |
Resveratrol prevents neuronal apoptosis in an early brain injury model.
Topics: Animals; Antioxidants; Apoptosis; Brain Injuries; Disease Models, Animal; Early Diagnosis; Interneurons; Male; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Subarachnoid Hemorrhage | 2014 |
Resveratrol and its combination with α-tocopherol mediate salt adaptation in citrus seedlings.
Topics: alpha-Tocopherol; Antioxidants; Ascorbate Peroxidases; Carbohydrates; Catechol Oxidase; Chlorides; Citrus; Glutathione Reductase; Hydrogen Peroxide; Ion Transport; Lipid Peroxidation; Peroxidase; Photosynthesis; Plant Leaves; Plant Roots; Proline; Resveratrol; Salt Tolerance; Seedlings; Sodium; Sodium Chloride; Stilbenes; Superoxide Dismutase | 2014 |
Resveratrol inhibits phenotypic switching of neointimal vascular smooth muscle cells after balloon injury through blockade of Notch pathway.
Topics: Animals; Antioxidants; Aorta, Thoracic; Carotid Arteries; Carotid Artery Injuries; Cells, Cultured; Disease Models, Animal; Hyperplasia; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Resveratrol; Stilbenes; Time Factors | 2014 |
Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cytokines; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hepatocytes; Humans; Nicotinamide Phosphoribosyltransferase; Organ Specificity; Primary Cell Culture; Resveratrol; RNA, Messenger; S Phase Cell Cycle Checkpoints; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
Resveratrol and endometrium: a closer look at an active ingredient of red wine using in vivo and in vitro models.
Topics: Alkaline Phosphatase; Animals; Basic Helix-Loop-Helix Transcription Factors; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Diethylstilbestrol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endometrium; Estradiol; Estrogen Receptor alpha; Female; Heterografts; Humans; Ki-67 Antigen; Mice, Inbred C57BL; Mice, Knockout; Ovariectomy; Phytoestrogens; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Time Factors; Wine | 2014 |
Resveratrol plays dual roles in pancreatic cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Pancreatic Neoplasms; Resveratrol; RNA, Small Interfering; Stilbenes; Vascular Endothelial Growth Factor B | 2014 |
Mitochondrial biogenesis: pharmacological approaches.
Topics: Animals; DNA, Mitochondrial; Humans; Metformin; Mitochondria; Mitochondrial Diseases; Resveratrol; Stilbenes | 2014 |
Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes.
Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Humans; Inflammation; Interleukin-1beta; Interleukin-8; Middle Aged; Mitochondria; NF-kappa B; Oligomycins; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Synovial Membrane | 2014 |
Inhibition of CYP17A1 activity by resveratrol, piceatannol, and synthetic resveratrol analogs.
Topics: Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Male; Resveratrol; Steroid 17-alpha-Hydroxylase; Stilbenes | 2014 |
Resveratrol as a natural anti-tumor necrosis factor-α molecule: implications to dendritic cells and their crosstalk with mesenchymal stromal cells.
Topics: Cell Death; Cell Differentiation; Cell Movement; Cell Nucleus; Cell Proliferation; Coculture Techniques; Cytokines; Dendritic Cells; Humans; Inflammation; Mesenchymal Stem Cells; NF-kappa B; Phenotype; Protein Transport; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Resveratrol inhibits Staphylococcus aureus-induced TLR2/MyD88/NF-κB-dependent VCAM-1 expression in human lung epithelial cells.
Topics: Animals; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Humans; Lung; Male; Mice; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Staphylococcus aureus; Stilbenes; Toll-Like Receptor 2; Vascular Cell Adhesion Molecule-1 | 2014 |
Resveratrol treatment has neuroprotective effects and prevents cognitive impairment after chronic cerebral hypoperfusion.
Topics: Animals; Brain Ischemia; Cell Count; Cognition Disorders; Hippocampus; Male; Maze Learning; Memory, Short-Term; Nerve Growth Factor; Neurons; Neuroprotective Agents; Neuropsychological Tests; Random Allocation; Rats, Wistar; Resveratrol; Spatial Memory; Stilbenes | 2014 |
Preparation of chitosan-TPP microspheres as resveratrol carriers.
Topics: Capsules; Chitosan; Drug Carriers; Hydrogen Bonding; Microspheres; Molecular Weight; Particle Size; Plant Extracts; Polyphosphates; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Ray Diffraction | 2014 |
Effect of hydrogen peroxide on contractility and citrate synthase activity of the rabbit urinary bladder in the presence and absence of resveratrol and a whole-grape suspension.
Topics: Animals; Antioxidants; Citrate (si)-Synthase; Electric Stimulation; Hydrogen Peroxide; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Plant Extracts; Rabbits; Resveratrol; Stilbenes; Suspensions; Urinary Bladder; Vitis | 2014 |
Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Carrier Proteins; Diet, High-Fat; Drug Evaluation, Preclinical; Eating; Hepatitis; Inflammasomes; Liver; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Organ Size; Resveratrol; Stilbenes | 2014 |
Health benefits of wine: don't expect resveratrol too much.
Topics: Antioxidants; Humans; Polyphenols; Resveratrol; Stilbenes; Wine | 2014 |
[Inhibitory effect of resveratrol on expression of IL-1β in mesenchymal stem cells exposed to radiation].
Topics: Cells, Cultured; Humans; Interleukin-1beta; Mesenchymal Stem Cells; Radiation; Radiation Dosage; Resveratrol; Stilbenes | 2014 |
The effects of resveratrol on hyperoxia-induced lung injury in neonatal rats.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bronchopulmonary Dysplasia; Disease Models, Animal; Humans; Hyperoxia; Infant, Newborn; Infant, Premature; Lung; Lung Injury; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties.
Topics: 2,6-Dichloroindophenol; Amino Acid Substitution; Dinitrocresols; Enzyme Inhibitors; Enzyme Stability; Humans; Isoenzymes; Kinetics; Niacinamide; Oxidation-Reduction; Polymorphism, Single Nucleotide; Proteolysis; Quinone Reductases; Resveratrol; Stilbenes | 2014 |
Resveratrol protects chondrocytes from apoptosis via altering the ultrastructural and biomechanical properties: an AFM study.
Topics: Actins; Animals; Apoptosis; Biomechanical Phenomena; Cell Membrane; Cell Survival; Chondrocytes; Microscopy, Atomic Force; Nitroprusside; Rabbits; Resveratrol; Stilbenes; Tubulin | 2014 |
Protective effect of resveratrol derivatives on high-fat diet induced fatty liver by activating AMP-activated protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Cell Survival; Enzyme Activation; Fatty Acids, Nonesterified; Gene Expression Regulation; Hepatocytes; Humans; Lipotropic Agents; Male; Methylation; Mice, Inbred ICR; Non-alcoholic Fatty Liver Disease; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats; Resveratrol; Specific Pathogen-Free Organisms; Stilbenes | 2014 |
Trans-resveratrol concentrations and antimutagenic potential of juice from the grape cultivars Vênus, BRS Violeta and Isabel.
Topics: Antimutagenic Agents; Aspergillus nidulans; Beverages; Microbial Viability; Mutation; Plant Extracts; Resveratrol; Spores, Fungal; Stilbenes; Vitis | 2014 |
The different effects of resveratrol and naringenin on isolated human umbilical vein: the role of ATP-sensitive K⁺ channels.
Topics: Adult; Female; Flavanones; Glyburide; Guanidines; Humans; In Vitro Techniques; KATP Channels; Pyridines; Resveratrol; Stilbenes; Umbilical Veins; Vasodilator Agents | 2014 |
Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Topics: Animals; Cardiotonic Agents; Diabetic Cardiomyopathies; Electron Transport Chain Complex Proteins; Fibrosis; Glutathione; Glutathione Disulfide; Heart Ventricles; Kinetics; Lipid Metabolism; Male; Mitochondria, Heart; Palmitoyl Coenzyme A; Rats, Zucker; Resveratrol; Stilbenes; Ventricular Function, Left | 2014 |
Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart.
Topics: Acetylation; Aging; Animals; Apoptosis; Collagen; Electron Transport Complex IV; Forkhead Box Protein O1; Forkhead Transcription Factors; Heart; Heart Rate; Mice; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Ventricular Function, Left | 2014 |
Estimation of resveratrol content in peanut pericarp and its relation to the in vitro inhibitory activity on carbohydrate metabolizing enzymes.
Topics: alpha-Amylases; Antioxidants; Arachis; beta-Galactosidase; Calibration; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; Magnetic Resonance Spectroscopy; Plant Extracts; Quality Control; Reference Standards; Resveratrol; Spectrophotometry, Ultraviolet; Stilbenes | 2014 |
Cross talk between angiotensin-(1-7)/Mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice.
Topics: Administration, Oral; Angiotensin I; Animals; Antimetabolites; Cells, Cultured; Diet, High-Fat; Drug Evaluation, Preclinical; Gene Expression; Glucose Intolerance; Hyperinsulinism; Insulin Resistance; Intra-Abdominal Fat; Lipolysis; Male; Mice; Obesity; Peptide Fragments; Primary Cell Culture; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Resistin; Resveratrol; Sirtuins; Stilbenes | 2014 |
Resveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.
Topics: Animals; Antioxidants; Brain; Cell Culture Techniques; Cellular Senescence; Endothelial Cells; Liposomes; Male; NF-E2-Related Factor 2; Oxidative Stress; Pharmaceutical Vehicles; Rats; Rats, Inbred BN; Rats, Inbred F344; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Synergistic antitumor activity of resveratrol and miR-200c in human lung cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Mice; Mice, Nude; MicroRNAs; Neoplasm Transplantation; Resveratrol; Ribonucleotide Reductases; Stilbenes; Transfection; Transplantation, Heterologous | 2014 |
The short term effects of resveratrol on ischemia-reperfusion injury in rat testis.
Topics: Albumins; Animals; Antioxidants; Apoptosis; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Spermatic Cord Torsion; Spermatozoa; Stilbenes; Testis | 2014 |
A study on the effect of resveratrol on lipid metabolism in hyperlipidemic mice.
Topics: Animals; Arteriosclerosis; Cholesterol; Dose-Response Relationship, Drug; Fallopia japonica; Hyperlipidemias; Lipid Metabolism; Male; Mice; Phytotherapy; Plant Extracts; Resveratrol; Stilbenes; Triglycerides | 2014 |
One-step reduction and PEGylation of graphene oxide for photothermally controlled drug delivery.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Graphite; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Infrared Rays; Lysosomes; Membrane Potential, Mitochondrial; Mice; Nanostructures; Oxides; Polyethylene Glycols; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits glucose-induced migration of vascular smooth muscle cells mediated by focal adhesion kinase.
Topics: Animals; Cell Movement; Cell Survival; Cells, Cultured; CSK Tyrosine-Protein Kinase; Focal Adhesion Protein-Tyrosine Kinases; Glucose; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Microscopy, Atomic Force; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pseudopodia; Resveratrol; RNA, Messenger; src-Family Kinases; Stilbenes; Wound Healing | 2014 |
Optimized PLGA nanoparticle platform for orally dosed trans-resveratrol with enhanced bioavailability potential.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Carriers; Emulsifying Agents; Intestinal Absorption; Lactic Acid; Male; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Resveratrol; Stilbenes; Tissue Distribution | 2014 |
Resveratrol metabolism in a non-human primate, the grey mouse lemur (Microcebus murinus), using ultra-high-performance liquid chromatography-quadrupole time of flight.
Topics: Administration, Oral; Animals; Blood Chemical Analysis; Cheirogaleidae; Chromatography, High Pressure Liquid; Humans; Male; Mass Spectrometry; Mice; Rats; Resveratrol; Stilbenes | 2014 |
[Resveratrol can reduce the expression of WT1 by methylation in K562 cells].
Topics: Cell Proliferation; DNA Methylation; Humans; K562 Cells; Resveratrol; Stilbenes; WT1 Proteins | 2014 |
Protein kinase C epsilon regulates mitochondrial pools of Nampt and NAD following resveratrol and ischemic preconditioning in the rat cortex.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Cytokines; Enzyme Inhibitors; Ischemic Preconditioning; Mitochondria; NAD; Nicotinamide Phosphoribosyltransferase; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Antiaging properties of a grape-derived antioxidant are regulated by mitochondrial balance of fusion and fission leading to mitophagy triggered by a signaling network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN.
Topics: Aging; Animals; Antioxidants; Apoptosis; Blotting, Western; Fluorescent Antibody Technique; Forkhead Box Protein O3; Forkhead Transcription Factors; Glutathione; Heart Ventricles; In Vitro Techniques; Intracellular Space; Male; Mitochondrial Dynamics; Mitophagy; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Ubiquitin-Protein Ligases; Vitis | 2014 |
On the molecular pharmacology of resveratrol on oxidative burst inhibition in professional phagocytes.
Topics: Animals; Cell Line; Cell Separation; Cell Survival; Free Radical Scavengers; Humans; Lipid Peroxidation; Luminescent Measurements; Luminol; Mice; Neutrophils; Nitric Oxide Synthase Type II; Nitrites; Phagocytes; Protein Kinases; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances | 2014 |
A new antioxidant stilbene and other constituents from the stem bark of Morus nigra L.
Topics: Antioxidants; Benzofurans; Benzothiazoles; Egypt; Flavonoids; Molecular Structure; Morus; Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Extracts; Resveratrol; Stilbenes; Sulfonic Acids; Terpenes | 2014 |
Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; AMP-Activated Protein Kinases; Animals; Apoptosis; Atrial Remodeling; Benzamides; Benzodioxoles; Calcium; Cardiomegaly; Fibrosis; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Ion Channels; Mice; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocardial Contraction; Myocardium; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxides; Transcription Factors; Uncoupling Protein 2 | 2014 |
Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death.
Topics: Animals; Apoptosis; Astrocytes; Autophagy; Brain Injuries; Cell Line; Cell Survival; Cytoprotection; Enzyme Activation; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Mitochondria; Neuroprotective Agents; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Time Factors | 2014 |
Effects of resveratrol on the insulin signaling pathway of obese mice.
Topics: Animals; Anti-Inflammatory Agents; Fluorescent Antibody Technique; Insulin; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Phosphorylation; Proteins; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Anti-inflammatory effect of resveratrol on adjuvant arthritis rats with abnormal immunological function via the reduction of cyclooxygenase-2 and prostaglandin E2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Cyclooxygenase 2; Dinoprostone; Lymphocyte Activation; Lymphocytes; Male; Rats; Resveratrol; Stilbenes; Synovial Membrane | 2014 |
9-Membered carbocycle formation: development of distinct Friedel-Crafts cyclizations and application to a scalable total synthesis of (±)-caraphenol A.
Topics: Biological Products; Catalysis; Cyclization; Molecular Structure; Phenols; Resveratrol; Stereoisomerism; Stilbenes | 2014 |
Role of the TLR4 pathway in blood-spinal cord barrier dysfunction during the bimodal stage after ischemia/reperfusion injury in rats.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Antioxidants; Calcium-Binding Proteins; Capillary Permeability; CD13 Antigens; Disease Models, Animal; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Microfilament Proteins; Myeloid Differentiation Factor 88; Peptides; Rats; Reperfusion Injury; Resveratrol; Signal Transduction; Spinal Cord; Spinal Cord Ischemia; Stilbenes; Sulfonamides; Time Factors; Toll-Like Receptor 4 | 2014 |
Editorial comment.
Topics: Animals; Antioxidants; Male; Resveratrol; Spermatic Cord Torsion; Stilbenes | 2014 |
Effect of antioxidants on outcome of testicular torsion in rats of different ages.
Topics: Animals; Antioxidants; Arginine; Male; Rats; Resveratrol; Spermatic Cord Torsion; Stilbenes; Testis; Treatment Outcome | 2014 |
Resveratrol protects primary cortical neuron cultures from transient oxygen-glucose deprivation by inhibiting MMP-9.
Topics: Animals; Apoptosis; Cell Survival; Cerebral Cortex; Extracellular Signal-Regulated MAP Kinases; Female; Glucose; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Neurons; Neuroprotective Agents; Oxygen; Pregnancy; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Resveratrol attenuates the inflammatory reaction induced by ischemia/reperfusion in the rat heart.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Disease Models, Animal; Inflammation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Neutrophil Infiltration; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Caloric restriction maintains OX40 agonist-mediated tumor immunity and CD4 T cell priming during aging.
Topics: Adoptive Transfer; Aging; Animals; Anticarcinogenic Agents; Blotting, Western; Caloric Restriction; CD4-Positive T-Lymphocytes; Female; Flow Cytometry; Humans; Immunotherapy; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Receptors, OX40; Resveratrol; Stilbenes; Survival Rate; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory | 2014 |
Use of red blood cell membranes to evaluate the antioxidant potential of plant extracts.
Topics: Animals; Antioxidants; Beverages; Drug Evaluation, Preclinical; Erythrocyte Membrane; Erythrocytes; Lythraceae; Male; Plant Extracts; Rats, Sprague-Dawley; Resveratrol; Sensitivity and Specificity; Stilbenes; Thiobarbituric Acid Reactive Substances; Ultraviolet Rays; Wine | 2014 |
Flavonoids and stilbenoids from Derris eriocarpa.
Topics: Anti-Infective Agents; Arthrodermataceae; Bacteria; Derris; Flavonoids; Isoflavones; Magnetic Resonance Spectroscopy; Medicine, Chinese Traditional; Microbial Sensitivity Tests; Molecular Structure; Plant Extracts; Plant Stems; Plants, Medicinal; Resveratrol; Stilbenes; Yeasts | 2014 |
Comparison of solubilization capacity of resveratrol in sodium 3α, 12α -dihydroxy-7-oxo-5 β-cholanoate and sodium dodecyl sulfate.
Topics: Capsules; Diffusion; Drug Compounding; Lithocholic Acid; Micelles; Resveratrol; Sodium Dodecyl Sulfate; Solubility; Stilbenes; Surface-Active Agents | 2014 |
Protective effects of bilberry and lingonberry extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro.
Topics: Animals; Anthocyanins; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Survival; In Vitro Techniques; Light; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Photoreceptor Cells, Vertebrate; Phytotherapy; Plant Extracts; Polyphenols; Reactive Oxygen Species; Resveratrol; Retina; Retinal Diseases; Stilbenes; Tetrazolium Salts; Vaccinium myrtillus; Vaccinium vitis-idaea | 2014 |
Synthesis, antioxidant and photoprotection activities of hybrid derivatives useful to prevent skin cancer.
Topics: Antioxidants; Cinnamates; Humans; Propiophenones; Resveratrol; Skin Neoplasms; Stilbenes; Sun Protection Factor; Sunscreening Agents; Ultraviolet Rays | 2014 |
Resveratrol attenuates high-fat diet-induced disruption of the blood-brain barrier and protects brain neurons from apoptotic insults.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain; Diet, High-Fat; Dietary Fats; Humans; Intracranial Arteriosclerosis; Male; Mice; Mice, Inbred ICR; Neurons; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits glycine receptor-mediated ion currents.
Topics: Animals; Dose-Response Relationship, Drug; Electric Conductivity; Glycine; Humans; Membrane Potentials; Oocytes; Receptors, Glycine; Resveratrol; Stilbenes; Xenopus laevis | 2014 |
[Resveratrol attenuates endoplasmic reticulum stress and alveolar epithelial apoptosis in a rat model of chronic obstructive pulmonary disease].
Topics: Alveolar Epithelial Cells; Animals; Antioxidants; Apoptosis; Caspase 12; Disease Models, Animal; Endoplasmic Reticulum Stress; Lipopolysaccharides; Lung; Male; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Resveratrol; Smoke; Stilbenes; Transcription Factor CHOP | 2014 |
Fluorogenic resveratrol-confined graphene oxide for economic and rapid detection of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Fluorescence; Fluorescent Antibody Technique; Graphite; Humans; Mice; Resveratrol; Stilbenes | 2014 |
Sirtuin 1 stabilization by HuR represses TNF-α- and glucose-induced E-selectin release and endothelial cell adhesiveness in vitro: relevance to human metabolic syndrome.
Topics: Acetylation; Adhesiveness; Benzamides; Cell Adhesion; E-Selectin; ELAV Proteins; Endothelial Cells; Gene Expression Regulation; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Leukocytes, Mononuclear; Metabolic Syndrome; Naphthols; NF-kappa B; Protein Stability; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
MAP Kinase cross talks in oxidative stress-induced impairment of insulin secretion. Involvement in the protective activity of quercetin.
Topics: Animals; Calcium Channels, L-Type; Cell Line; Hydrogen Peroxide; Insulin; Insulin Secretion; Insulin-Secreting Cells; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphorylation; Quercetin; Rats; Resveratrol; Stilbenes | 2014 |
Study to evaluate molecular mechanics behind synergistic chemo-preventive effects of curcumin and resveratrol during lung carcinogenesis.
Topics: Analysis of Variance; Animals; Benzo(a)pyrene; Blotting, Western; Carbon Radioisotopes; Carcinogenesis; Curcumin; Drug Synergism; Immunohistochemistry; Lung Neoplasms; Mice; Phosphorylation; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
Leukocyte production of inflammatory mediators is inhibited by the antioxidants phloretin, silymarin, hesperetin, and resveratrol.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Differentiation; Cells, Cultured; Cytokines; Escherichia coli; Hesperidin; Humans; I-kappa B Proteins; Inflammation; Leukocytes; Leukocytes, Mononuclear; Lipopolysaccharides; Monocytes; Neutrophils; NF-KappaB Inhibitor alpha; Phloretin; Resveratrol; RNA, Messenger; Silymarin; Stilbenes | 2014 |
Effect of resveratrol on chromosomal aberrations induced by doxorubicin in rat bone marrow cells.
Topics: Animals; Antibiotics, Antineoplastic; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; Doxorubicin; Male; Metaphase; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plants.
Topics: Animals; Biological Products; Chemical Fractionation; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drugs, Chinese Herbal; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Intestinal Mucosa; Male; Mice; Molecular Structure; Plants, Medicinal; Rats; Resveratrol; Stilbenes | 2014 |
Resveratrol-induced potentiation of the antitumor effects of oxaliplatin is accompanied by an altered cytokine profile of human monocyte-derived macrophages.
Topics: Antineoplastic Agents; Apoptosis; Blood Platelets; Caco-2 Cells; Coculture Techniques; Colorectal Neoplasms; Cytokines; Drug Synergism; Fibroblasts; Humans; Macrophages; Organoplatinum Compounds; Oxaliplatin; Resveratrol; Stilbenes; Transcriptome | 2014 |
Antidepressant effects of resveratrol in an animal model of depression.
Topics: Anhedonia; Animals; Antidepressive Agents; Blotting, Western; Brain-Derived Neurotrophic Factor; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Frontal Lobe; Hippocampus; Male; Motor Activity; Neuropsychological Tests; Rats, Inbred WKY; Resveratrol; Stilbenes; Time Factors | 2014 |
Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue; Angiopoietin-Like Protein 4; Angiopoietins; Animals; Bifidobacterium; Blood Glucose; Body Weight; Diet, High-Fat; Enterococcus faecalis; fas Receptor; Gastrointestinal Tract; Lactobacillus; Lipids; Lipogenesis; Liver; Male; Mice; Microbiota; Obesity; PPAR gamma; Resveratrol; Signal Transduction; Stearoyl-CoA Desaturase; Stilbenes | 2014 |
Radioprotective and antioxidant effect of resveratrol in hippocampus by activating Sirt1.
Topics: Animals; Antioxidants; Apoptosis; Enzyme Activation; Hippocampus; Male; Mitochondria; Oxidation-Reduction; Oxidative Stress; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Ribonucleotide Reductases; RNA, Messenger; Sirtuin 1; Stilbenes | 2014 |
Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration.
Topics: Calcium Signaling; Cell Line, Tumor; Cell Membrane; Cell Movement; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Humans; Pancreatic Neoplasms; Protein Conformation; Protein Glutamine gamma Glutamyltransferase 2; Protein Transport; Resveratrol; Stilbenes; Transglutaminases | 2014 |
Resveratrol inhibition of human keratinocyte proliferation via SIRT1/ARNT/ERK dependent downregulation of aquaporin 3.
Topics: Aquaporin 3; Aryl Hydrocarbon Receptor Nuclear Translocator; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Phosphorylation; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Transfection | 2014 |
Determination of polyphenolic compounds of red wines by UV-VIS-NIR spectroscopy and chemometrics tools.
Topics: Chromatography, High Pressure Liquid; Flavonoids; Polyphenols; Resveratrol; Spectroscopy, Near-Infrared; Stilbenes; Wine | 2014 |
Resveratrol inhibits phenotype modulation by platelet derived growth factor-bb in rat aortic smooth muscle cells.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Becaplermin; Cell Dedifferentiation; Cell Proliferation; Cell Shape; Myocytes, Smooth Muscle; Phenotype; Proto-Oncogene Proteins c-sis; Rats; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Redox regulation of antioxidant enzymes: post-translational modulation of catalase and glutathione peroxidase activity by resveratrol in diabetic rat liver.
Topics: Animals; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glutathione Peroxidase; Humans; Liver; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Rats; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2014 |
Sirt1 activity in peripheral blood mononuclear cells from patients with rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Leukocytes, Mononuclear; Middle Aged; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function.
Topics: Animals; Anti-Asthmatic Agents; Apoptosis; Caspase 9; Cell Line; Cytochromes c; Dimerization; Humans; Lung; Male; Membrane Potential, Mitochondrial; Mice, Inbred BALB C; Mitochondria; Nicotiana; Respiratory Mucosa; Resveratrol; Smoke; Smoking; Stilbenes; Vitis | 2014 |
Relationship between mitochondrial DNA copy number and SIRT1 expression in porcine oocytes.
Topics: Animals; DNA, Mitochondrial; Female; Gene Dosage; Gene Expression Regulation, Enzymologic; Oocytes; Resveratrol; Sirtuin 1; Stilbenes; Swine | 2014 |
Biotechnological production of plant-specific hydroxylated phenylpropanoids.
Topics: Escherichia coli; Metabolic Engineering; Resveratrol; Stilbenes; Umbelliferones | 2014 |
Resveratrol stimulates AP-1-regulated gene transcription.
Topics: Cyclin D1; Dual Specificity Phosphatase 1; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
The PTEN/PI3K/Akt and Wnt/β-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Mice; Mice, Nude; Neoplasms, Experimental; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2014 |
Resveratrol reduces morphine tolerance by inhibiting microglial activation via AMPK signalling.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cell Line; Drug Tolerance; Interleukin-1beta; Interleukin-6; Mice; Microglia; Morphine; NF-kappa B; Nitric Oxide Synthase Type II; Nociceptive Pain; p38 Mitogen-Activated Protein Kinases; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2014 |
Protective effect of resveratrol against IL-1β-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-κB signaling pathway: an "in vitro study".
Topics: Aged; Cell Survival; Cells, Cultured; Chondrocytes; Humans; Interleukin-1beta; Middle Aged; Myeloid Differentiation Factor 88; NF-kappa B; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stilbenes; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Novel PPAR pan agonist, ZBH ameliorates hyperlipidemia and insulin resistance in high fat diet induced hyperlipidemic hamster.
Topics: Animals; Bezafibrate; Cricetinae; Diet, High-Fat; Drug Design; Gene Expression Regulation; Hyperinsulinism; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Muscle, Skeletal; Pentanoic Acids; PPAR alpha; Resveratrol; Sirtuin 1; Stilbenes; Triglycerides | 2014 |
Resveratrol induces expression of the slow, oxidative phenotype in mdx mouse muscle together with enhanced activity of the SIRT1-PGC-1α axis.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Disease Models, Animal; Glycolysis; Male; Mice; Mice, Inbred mdx; Muscle Development; Muscle Fibers, Slow-Twitch; Muscular Dystrophy, Duchenne; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phenotype; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors | 2014 |
Phenolic composition of grape and winemaking by-products of Brazilian hybrid cultivars BRS Violeta and BRS Lorena.
Topics: Anthocyanins; Brazil; Chromatography, High Pressure Liquid; Coumaric Acids; Flavonols; Phenols; Proanthocyanidins; Resveratrol; Stilbenes; Vitis; Wine | 2014 |
Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.
Topics: Adenylate Kinase; Cyclic AMP; Estrogen Receptor alpha; Female; Humans; Inflammation; Interleukin-6; Ligands; MCF-7 Cells; Promoter Regions, Genetic; Protein Conformation; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Ischemia-induced endothelial cell swelling and mitochondrial dysfunction are attenuated by cinnamtannin D1, green tea extract, and resveratrol in vitro.
Topics: Animals; Antioxidants; Brain Ischemia; Calcium; Cell Line; Chemokine CCL2; Cyclosporine; Egtazic Acid; Endothelial Cells; Glucose; Hypoxia; Interleukin-6; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Plant Extracts; Polyphenols; Proanthocyanidins; Reactive Oxygen Species; Resveratrol; Stilbenes; Tea; Tumor Necrosis Factor-alpha | 2015 |
Stability of trans-resveratrol associated with transport proteins.
Topics: Carrier Proteins; Humans; Kinetics; Lactoglobulins; Protein Binding; Resveratrol; Serum Albumin; Stereoisomerism; Stilbenes; Temperature | 2014 |
Natural immunomodulators and their stimulation of immune reaction: true or false?
Topics: Animals; beta-Glucans; Carcinoma, Lewis Lung; Female; Humans; Immune System; Immunologic Factors; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes | 2014 |
In-vitro/in-vivo characterization of trans-resveratrol-loaded nanoparticulate drug delivery system for oral administration.
Topics: Acrylic Resins; Administration, Oral; Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Intestinal Absorption; Male; Nanoparticles; Particle Size; Permeability; Pharmaceutical Preparations; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes | 2014 |
Co-encapsulation of resveratrol and curcumin in lipid-core nanocapsules improves their in vitro antioxidant effects.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Curcumin; Drug Delivery Systems; Free Radicals; Humans; Hydrogen-Ion Concentration; Inflammation; Lipids; Microscopy, Electron, Transmission; Nanocapsules; Nanoparticles; Nanotechnology; Oxidative Stress; Particle Size; Polyphenols; Resveratrol; Stilbenes | 2014 |
Preferential expression of PAPPA in human preadipocytes from omental fat.
Topics: Adipocytes; Adult; AMP-Activated Protein Kinases; Cells, Cultured; Female; Gene Expression Regulation; Humans; Interleukin-1beta; Intra-Abdominal Fat; Male; Mesentery; Omentum; Pregnancy-Associated Plasma Protein-A; Resveratrol; Signal Transduction; Sirtuin 1; Stem Cells; Stilbenes; Subcutaneous Fat; Tumor Necrosis Factor-alpha | 2014 |
Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.
Topics: Animals; Cell Line; Colitis; Collagen Type I; Colon; Disease Models, Animal; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Insulin-Like Growth Factor I; Male; MAP Kinase Kinase Kinases; Mice; Mutation; Phosphorylation; Rats, Sprague-Dawley; Receptor, IGF Type 1; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Transfection; Trinitrobenzenesulfonic Acid | 2014 |
Combined effects of sivelestat and resveratrol on severe acute pancreatitis-associated lung injury in rats.
Topics: Acute Disease; Amylases; Animals; Arterial Pressure; Bronchoalveolar Lavage Fluid; Glycine; Interleukin-6; Leukocyte Elastase; Lung; Lung Injury; Male; Oxygen; Pancreatitis; Peroxidase; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfonamides | 2014 |
Resveratrol against Arcobacter butzleri and Arcobacter cryaerophilus: activity and effect on cellular functions.
Topics: Anti-Bacterial Agents; Arcobacter; DNA, Bacterial; Food Microbiology; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Resveratrol; Stilbenes | 2014 |
Resveratrol and its metabolites bind to PPARs.
Topics: Binding Sites; Crystallography, X-Ray; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Models, Molecular; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Resveratrol; Rosiglitazone; Stilbenes; Structure-Activity Relationship; Thiazolidinediones; Tumor Cells, Cultured | 2014 |
Ex vivo molecular rejuvenation improves the therapeutic activity of senescent human cardiac stem cells in a mouse model of myocardial infarction.
Topics: Animals; Cellular Senescence; Disease Models, Animal; Female; Humans; Mice; Mice, SCID; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Signal Transduction; Sirolimus; Stem Cell Transplantation; Stilbenes | 2014 |
Calorie restriction-induced changes in the secretome of human adipocytes, comparison with resveratrol-induced secretome effects.
Topics: Adipocytes; Adipokines; Adipose Tissue, White; Antioxidants; Arrhythmias, Cardiac; Caloric Restriction; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Genetic Diseases, X-Linked; Gigantism; Glucose; Heart Defects, Congenital; Humans; Insulin Resistance; Intellectual Disability; Molecular Sequence Annotation; Obesity; Proteome; Proteomics; Resveratrol; Sirtuin 1; Stilbenes; Tandem Mass Spectrometry | 2014 |
Resveratrol reduces the proinflammatory effects and lipopolysaccharide- induced expression of HMGB1 and TLR4 in RAW264.7 cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Dose-Response Relationship, Drug; HMGB1 Protein; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Resveratrol; RNA, Messenger; Stilbenes; Structure-Activity Relationship; Toll-Like Receptor 4 | 2014 |
Amelioration of streptozotocin-induced diabetic nephropathy by melatonin, quercetin, and resveratrol in rats.
Topics: Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Catalase; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Kidney; Male; Malondialdehyde; Melatonin; Quercetin; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
PTEN mediates the antioxidant effect of resveratrol at nutritionally relevant concentrations.
Topics: Antioxidants; Catalase; Enzyme Activation; Humans; Hydrogen Peroxide; MCF-7 Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase; Up-Regulation | 2014 |
Regulatory effects of resveratrol on glucose metabolism and T-lymphocyte subsets in the development of high-fat diet-induced obesity in C57BL/6 mice.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Glucose; Body Weight; Diet, High-Fat; Fasting; Female; Inflammation; Insulin; Leptin; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Obesity; Oxidative Stress; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; T-Lymphocyte Subsets | 2014 |
Suppression by resveratrol of prostaglandin D2-stimulated osteoprotegerin synthesis in osteoblasts.
Topics: Animals; Cell Line; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; MAP Kinase Signaling System; Mice; Osteoblasts; Osteoprotegerin; Prostaglandin D2; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes | 2014 |
Resveratrol alleviates lung ischemia and reperfusion-induced pulmonary capillary injury through modulating pulmonary mitochondrial metabolism.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Capillaries; Cytoprotection; Leukocytes; Lung; Lung Injury; Male; Malondialdehyde; Mitochondria; Mitochondrial Turnover; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factors | 2014 |
Resveratrol-loaded nanocarriers: formulation, optimization, characterization and in vitro toxicity on cochlear cells.
Topics: Cell Death; Cell Line; Cell Survival; Cochlea; Cryoprotective Agents; Drug Carriers; Freeze Drying; Humans; Kinetics; Nanoparticles; Resveratrol; Stilbenes; Toxicity Tests; X-Ray Diffraction | 2014 |
Role of microRNAs in resveratrol-mediated mitigation of colitis-associated tumorigenesis in Apc(Min/+) mice.
Topics: Animals; Carcinogenesis; Cell Proliferation; Colitis; Colon; Colonic Polyps; Cyclooxygenase 2; Dextran Sulfate; Epithelial Cells; Female; Gene Expression Regulation; Interleukin-6; Intestinal Polyps; Lymphocytes; Male; Mice; Mice, Mutant Strains; MicroRNAs; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Inhibition of age-related cytokines production by ATGL: a mechanism linked to the anti-inflammatory effect of resveratrol.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cytokines; Interleukin-6; Lipase; Male; Mice; Mice, Inbred C57BL; PPAR alpha; PPAR gamma; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
[Therapeutic effect of resveratrol as well as resveratrol combined with praziquantel on the liver fibrosis due to Schistosoma japonicum infection in mice].
Topics: Animals; Drug Therapy, Combination; Female; Liver Cirrhosis; Male; Mice; Oxidative Stress; Praziquantel; Resveratrol; Schistosoma japonicum; Schistosomiasis japonica; Stilbenes; Vascular Endothelial Growth Factor A | 2013 |
Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease.
Topics: Animals; Atherosclerosis; Capillary Permeability; Endothelial Cells; Endothelium, Vascular; Fluorouracil; Humans; Ischemia; Mice; Microfluidic Analytical Techniques; Oxygen Consumption; Resveratrol; Stilbenes; Stress, Mechanical; Vascular Diseases | 2014 |
Protective effect of resveratrol against acute lung injury induced by lipopolysaccharide via inhibiting the myd88-dependent Toll-like receptor 4 signaling pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Cyclooxygenase 2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Leukocytes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Myeloid Differentiation Factor 88; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4 | 2014 |
Alternative oxidase inhibitors as antiparasitic agents against scuticociliatosis.
Topics: Animals; Antimycin A; Antioxidants; Antiparasitic Agents; Cell Respiration; Flatfishes; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Oligohymenophorea; Oxidative Stress; Oxidoreductases; Plant Proteins; Propyl Gallate; Resveratrol; Stilbenes | 2014 |
Three new resveratrol derivatives from the mangrove endophytic fungus Alternaria sp.
Topics: Alternaria; Antibiotics, Antineoplastic; Antioxidants; Cell Line, Tumor; Fermentation; Free Radical Scavengers; Humans; Myoporum; Resveratrol; Stilbenes | 2014 |
Chemotherapy pro-drug activation by biocatalytic virus-like nanoparticles containing cytochrome P450.
Topics: Activation, Metabolic; Antineoplastic Agents; Bacillus megaterium; Bacterial Proteins; Biocatalysis; Bromovirus; Capsid Proteins; Cytochrome P-450 Enzyme System; Drug Carriers; Drug Delivery Systems; Humans; Kinetics; Nanocapsules; Nanoparticles; Prodrugs; Resveratrol; Stilbenes; Tamoxifen; Virion | 2014 |
Chronic resveratrol treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with mononeuropathy: involvement of serotonergic system.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Brain; Comorbidity; Constriction, Pathologic; Depression; Disease Models, Animal; Hot Temperature; Hyperalgesia; Male; Mice, Inbred C57BL; Neuralgia; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Resveratrol; Sciatic Neuropathy; Spinal Cord; Stilbenes; Touch | 2014 |
Resveratrol and pharmacological potentiation in ischemic stroke.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Humans; Resveratrol; Stilbenes; Stroke; Treatment Outcome | 2014 |
Ab initio calculations on the (1)O2 quenching mechanism by trans-resveratrol.
Topics: Cycloaddition Reaction; Oxygen; Resveratrol; Stilbenes; Thermodynamics | 2014 |
Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-kβ.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Screening Assays, Antitumor; Humans; Male; NF-kappa B; Polyphenols; Promoter Regions, Genetic; Prostatic Neoplasms, Castration-Resistant; Resveratrol; Stilbenes; Transcriptional Activation; Wine | 2014 |
Complexation of resveratrol with soy protein and its improvement on oxidative stability of corn oil/water emulsions.
Topics: Antioxidants; Corn Oil; Drug Stability; Emulsions; Fluorescence; Oxidation-Reduction; Particle Size; Resveratrol; Solubility; Soybean Proteins; Stilbenes; Water | 2014 |
Resveratrol inhibits oxygen-glucose deprivation-induced MMP-3 expression and cell apoptosis in primary cortical cells via the NF-κB pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Gene Expression; Glucose; Matrix Metalloproteinase 3; Mice; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroso Compounds; Proline; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Stilbenes; Thiocarbamates | 2014 |
Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways.
Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Differentiation; Cell Line, Tumor; Chondrosarcoma; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pyridines; Resveratrol; Stilbenes | 2014 |
Harnessing quinone methides: total synthesis of (±)-vaticanol A.
Topics: Biological Products; Indolequinones; Resveratrol; Stereoisomerism; Stilbenes | 2014 |
Implications of differential stress response activation following non-frozen hepatocellular storage.
Topics: Animals; Cell Survival; Cells, Cultured; Cinnamates; Cold Temperature; Culture Media; Hep G2 Cells; Hepatocytes; Humans; Microscopy, Fluorescence; Rats; Resveratrol; Stilbenes; Thiourea; Time Factors; Unfolded Protein Response | 2013 |
Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Brain; Chemical and Drug Induced Liver Injury; Deoxyguanosine; Heart; Liver; Male; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Sodium Fluoride; Stilbenes | 2014 |
Therapy for neonatal hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Bronchopulmonary Dysplasia; Disease Models, Animal; Humans; Hyperoxia; Lung Injury; Rats; Resveratrol; Stilbenes | 2014 |
Dietary supplementation with resveratrol protects against striatal dopaminergic deficits produced by in utero LPS exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dietary Supplements; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Homovanillic Acid; Lipopolysaccharides; Maternal Nutritional Physiological Phenomena; Neurons; Neuroprotective Agents; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tyrosine 3-Monooxygenase | 2014 |
Resveratrol-zinc combination for prostate cancer management.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Homeostasis; Humans; Male; Prostate; Prostatic Neoplasms; Resveratrol; Stilbenes; Trace Elements; Zinc | 2014 |
Nutritional aspects of β-carotene and resveratrol antioxidant synergism in giant unilamellar vesicles.
Topics: Antioxidants; beta Carotene; Glycine max; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Oxidative Stress; Phosphatidylcholines; Resveratrol; Stilbenes; Unilamellar Liposomes | 2014 |
Resveratrol attenuates bone cancer pain through the inhibition of spinal glial activation and CX3CR1 upregulation.
Topics: Analgesics; Animals; Bone Neoplasms; CX3C Chemokine Receptor 1; Hyperalgesia; Injections, Spinal; Neuroglia; Pain; Rats; Rats, Sprague-Dawley; Receptors, Chemokine; Resveratrol; Stilbenes; Up-Regulation | 2014 |
Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenal Cortex Hormones; Aldo-Keto Reductase Family 1 Member C3; Androgens; Cell Line; Dehydroepiandrosterone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Hydrocortisone; Hydroxyprostaglandin Dehydrogenases; Kinetics; Microsomes; Nonsteroidal Anti-Androgens; Polyphenols; Resveratrol; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Stilbenes | 2014 |
Resveratrol counteracts lipopolysaccharide-mediated microglial inflammation by modulating a SOCS-1 dependent signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Survival; Inflammation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Superoxides; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins | 2014 |
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.
Topics: Aldehydes; Animals; Aorta; Caspase 3; Cell Adhesion; Cells, Cultured; Diet, High-Fat; Endothelial Cells; Humans; Inflammation; Monocytes; Primates; Pulse Wave Analysis; Resveratrol; Stilbenes; Sucrose; Transcription, Genetic | 2014 |
Effect of short-term polyphenol treatment on endothelial dysfunction and thromboxane A2 levels in streptozotocin-induced diabetic mice.
Topics: Animals; Antioxidants; Aorta, Thoracic; Chlorogenic Acid; Diabetes Mellitus, Experimental; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Flavonoids; Isometric Contraction; Male; Mice, Inbred ICR; Muscle, Smooth, Vascular; Nitric Oxide; Oxidative Stress; Polyphenols; Resveratrol; Stilbenes; Streptozocin; Thromboxane A2 | 2014 |
Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity?
Topics: Adenylate Kinase; Amyotrophic Lateral Sclerosis; Animals; Drug Synergism; Mice; Mice, Transgenic; Morpholines; Neural Conduction; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Resveratrol; Rotarod Performance Test; Sigma-1 Receptor; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2014 |
Resveratrol-enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice.
Topics: Acetylation; Animals; Antioxidants; Apoptosis; Autophagy; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Experimental; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Oxidation-Reduction; Oxidative Stress; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2014 |
Resveratrol sensitizes HepG2 cells to TRAIL-induced apoptosis.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Down-Regulation; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins; Phosphorylation; Resveratrol; S Phase Cell Cycle Checkpoints; Stilbenes; Survivin; TNF-Related Apoptosis-Inducing Ligand | 2014 |
Resveratrol: a supplementation for men or for mice?
Topics: Dietary Supplements; Humans; Resveratrol; Stilbenes | 2014 |
Sirt1, a negative regulator of matrix metalloproteinase-9 in diabetic retinopathy.
Topics: Aged; Analysis of Variance; Animals; Apoptosis; Case-Control Studies; Cytochromes b; Diabetic Retinopathy; Endothelial Cells; Enzyme Inhibitors; Female; Histone Deacetylases; Humans; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitochondria; Oxidative Stress; Resveratrol; Retina; Sirtuin 1; Stilbenes | 2014 |
Development of an improved reverse-phase high-performance liquid chromatography method for the simultaneous analyses of trans-/cis-resveratrol, quercetin, and emodin in commercial resveratrol supplements.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Dietary Supplements; Emodin; Isomerism; Quercetin; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; NF-E2-Related Factor 2; Rats, Inbred ACI; Rats, Inbred Strains; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Stilbenes; Tumor Cells, Cultured | 2014 |
Resveratrol counteracts inflammation in human M1 and M2 macrophages upon challenge with 7-oxo-cholesterol: potential therapeutic implications in atherosclerosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cells, Cultured; Chemokines; Cytokines; Down-Regulation; Endocytosis; Humans; Inflammation; Intercellular Signaling Peptides and Proteins; Ketocholesterols; Lipopolysaccharide Receptors; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocytes; NF-kappa B; Receptors, IgG; Resveratrol; Stilbenes; Up-Regulation | 2014 |
Stilbenes and resveratrol metabolites improve mitochondrial fatty acid oxidation defects in human fibroblasts.
Topics: Blotting, Western; Fatty Acids; Fibroblasts; Humans; Mitochondria; Oxidation-Reduction; Resveratrol; Stilbenes | 2014 |
Resveratrol and arsenic trioxide act synergistically to kill tumor cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Drug Synergism; Humans; Male; Mice; Necrosis; Neovascularization, Pathologic; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Burden; Xenograft Model Antitumor Assays | 2014 |
The effects of resveratrol on tendon healing of diabetic rats.
Topics: Achilles Tendon; Animals; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Diabetes Mellitus, Experimental; Injections, Intraperitoneal; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tensile Strength; Treatment Outcome; Wound Healing | 2014 |
Lipid based nanoemulsifying resveratrol for improved physicochemical characteristics, in vitro cytotoxicity and in vivo antiangiogenic efficacy.
Topics: Aluminum Compounds; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Death; Cell Proliferation; Cell Survival; Chemical Phenomena; Chickens; Chorioallantoic Membrane; Drug Delivery Systems; Emulsions; Ethylene Glycols; Glycerides; Humans; Hydrogen-Ion Concentration; Lipids; Magnesium Compounds; MCF-7 Cells; Organic Chemicals; Particle Size; Phase Transition; Resveratrol; Silicates; Solubility; Static Electricity; Stilbenes; Thermodynamics | 2014 |
D-galactosamine/lipopolysaccharide-induced hepatotoxicity downregulates sirtuin 1 in rat liver: role of sirtuin 1 modulation in hepatoprotection.
Topics: Animals; Antioxidants; Carbazoles; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Galactosamine; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Effects of the compounds resveratrol, rutin, quercetin, and quercetin nanoemulsion on oxaliplatin-induced hepatotoxicity and neurotoxicity in mice.
Topics: Alanine Transaminase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Caspase 3; Emulsions; Fatty Liver; Hyperalgesia; Lumbar Vertebrae; Male; Mice, Inbred BALB C; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Peroxidase; Proto-Oncogene Proteins c-fos; Quercetin; Resveratrol; Rutin; Spinal Cord; Stilbenes | 2014 |
Lycopene and resveratrol improve post-thaw bull sperm parameters: sperm motility, mitochondrial activity and DNA integrity.
Topics: Acrosome; Animals; Antioxidants; Carotenoids; Cattle; Cryopreservation; DNA; DNA Damage; Lycopene; Male; Mitochondria; Oxidative Stress; Resveratrol; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes | 2015 |
Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway.
Topics: Activating Transcription Factor 3; Animals; Gene Expression Regulation; Glucuronidase; JNK Mitogen-Activated Protein Kinases; Klotho Proteins; Mice; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factor AP-1 | 2014 |
Polymeric micellar co-delivery of resveratrol and curcumin to mitigate in vitro doxorubicin-induced cardiotoxicity.
Topics: Antineoplastic Agents; Apoptosis; Cardiotoxicity; Cell Line; Cell Line, Tumor; Cell Survival; Curcumin; Doxorubicin; Drug Carriers; Drug Combinations; Female; Humans; Micelles; Myocytes, Cardiac; Ovarian Neoplasms; Poloxamer; Resveratrol; Stilbenes | 2014 |
Resveratrol in vitro ameliorates tert-butyl hydroperoxide-induced alterations in erythrocyte membranes from young and older humans.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Cells, Cultured; Erythrocyte Membrane; Female; Humans; Male; Middle Aged; Oxidation-Reduction; Resveratrol; Stilbenes; tert-Butylhydroperoxide; Young Adult | 2014 |
Preparation and in vitro/in vivo evaluation of resveratrol-loaded carboxymethyl chitosan nanoparticles.
Topics: Animals; Biological Availability; Chitosan; Drug Carriers; Gastrointestinal Tract; Male; Nanoparticles; Particle Size; Powders; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Solvents; Stilbenes | 2016 |
Antimicrobial activity of resveratrol analogues.
Topics: Anti-Infective Agents; Botrytis; Resveratrol; Stilbenes | 2014 |
Fermentation of Smilax china root by Aspergillus usami and Saccharomyces cerevisiae promoted concentration of resveratrol and oxyresveratrol and the free-radical scavenging activity.
Topics: Aspergillus; Benzothiazoles; Fermentation; Free Radical Scavengers; Glucosides; Humans; Plant Extracts; Plant Roots; Resveratrol; Saccharomyces cerevisiae; Smilax; Stilbenes; Sulfonic Acids | 2014 |
Resveratrol and clofarabine induces a preferential apoptosis-activating effect on malignant mesothelioma cells by Mcl-1 down-regulation and caspase-3 activation.
Topics: Adenine Nucleotides; Apoptosis; Arabinonucleosides; Caspase 3; Cell Line, Tumor; Clofarabine; Down-Regulation; Enzyme Activation; Humans; Mesothelioma; Myeloid Cell Leukemia Sequence 1 Protein; Resveratrol; Stilbenes | 2015 |
Tailoring 3,3'-dihydroxyisorenieratene to hydroxystilbene: finding a resveratrol analogue with increased antiproliferation activity and cell selectivity.
Topics: Antineoplastic Agents, Phytogenic; Carotenoids; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Discovery; Humans; Models, Molecular; Resveratrol; Stilbenes | 2014 |
Mechanisms of resveratrol-induced changes in cytosolic free calcium ion concentrations and cell viability in OC2 human oral cancer cells.
Topics: Apoptosis; Calcium; Cell Line, Tumor; Cell Survival; Cytosol; Humans; Mouth Neoplasms; Protein Kinase C; Resveratrol; Stilbenes; Type C Phospholipases | 2015 |
Anti-aromatase effect of resveratrol and melatonin on hormonal positive breast cancer cells co-cultured with breast adipose fibroblasts.
Topics: Adipose Tissue; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Estradiol; Female; Fibroblasts; Gene Expression Regulation; Humans; Ki-67 Antigen; Letrozole; Melatonin; Nitriles; Resveratrol; Stilbenes; Testosterone; Trefoil Factor-1; Triazoles; Tumor Suppressor Proteins | 2014 |
Effects of agmatine and resveratrol on RGC-5 cell behavior under light stimulation.
Topics: Agmatine; Animals; Calcium; Cell Line; Light; Nitric Oxide; Photic Stimulation; Protective Agents; Rats; Reactive Oxygen Species; Resveratrol; Retinal Ganglion Cells; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Direct activation of ATM by resveratrol under oxidizing conditions.
Topics: Antioxidants; Ataxia Telangiectasia Mutated Proteins; Bleomycin; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; HCT116 Cells; HEK293 Cells; Humans; Hydrogen Peroxide; Oxidants; Phosphorylation; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Analysis of influence of baicalin joint resveratrol retention enema on the TNF-α, SIgA, IL-2, IFN-γ of rats with respiratory syncytial virus infection.
Topics: Animals; Antiviral Agents; Cell Line; Drug Interactions; Enema; Female; Flavonoids; Humans; Immunoglobulin A, Secretory; Interferon-gamma; Interleukin-2; Male; Rats; Rats, Sprague-Dawley; Respiratory Syncytial Virus Infections; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.
Topics: Animals; Carrier Proteins; Drug Delivery Systems; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Resveratrol; Stilbenes; Stroke; Thioredoxins; Thromboembolism | 2015 |
Protective effect of resveratrol against doxorubicin-induced cardiac toxicity and fibrosis in male experimental rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Caspase 3; Doxorubicin; Fibrosis; Gene Expression; Glutathione; Heart; Heart Ventricles; Male; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase; Transforming Growth Factor beta1; Ventricular Remodeling | 2014 |
Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells.
Topics: Adaptor Proteins, Signal Transducing; Cell Death; Cell Line; Cytoprotection; Epithelial Cells; Gene Expression Regulation; Glutathione S-Transferase pi; Heme Oxygenase-1; Humans; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol; Retinal Pigment Epithelium; RNA, Messenger; Sequestosome-1 Protein; Stilbenes; Time Factors | 2014 |
Survivin suppression through STAT3/β-catenin is essential for resveratrol-induced melanoma apoptosis.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; beta Catenin; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Humans; Inhibitor of Apoptosis Proteins; Melanoma; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Stilbenes; Survivin; Xenograft Model Antitumor Assays | 2014 |
Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening and identifies a SIR-2.1-independent action of resveratrol.
Topics: Adult; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Drug Evaluation, Preclinical; HSP40 Heat-Shock Proteins; Humans; Life Expectancy; Membrane Proteins; Neuronal Ceroid-Lipofuscinoses; Resveratrol; Sirtuins; Stilbenes | 2014 |
Myb14, a direct activator of STS, is associated with resveratrol content variation in berry skin in two grape cultivars.
Topics: Acyltransferases; Fruit; Gene Expression Regulation, Plant; Plant Leaves; Plant Proteins; Resveratrol; Stilbenes; Vitis | 2014 |
Antitumoural activity of viniferin-enriched extracts from Vitis vinifera L. cell cultures.
Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Culture Techniques; Cell Proliferation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Fibroblasts; Humans; Mass Spectrometry; Plant Extracts; Resveratrol; Stereoisomerism; Stilbenes; Vitis | 2014 |
Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling.
Topics: Animals; Arginase; Cell Proliferation; Cells, Cultured; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Stilbenes | 2014 |
Resveratrol as anti-aging therapy for age-related bone loss.
Topics: Aging; Animals; Biomarkers; Biomechanical Phenomena; Body Weight; Bone Resorption; Collagen Type I; Femur; Male; Organ Size; Osteocalcin; Peptides; Rats, Wistar; Rejuvenation; Resveratrol; Stilbenes; X-Ray Microtomography | 2014 |
Resveratrol prevents hyperleptinemia and central leptin resistance in adult rats programmed by early weaning.
Topics: Animals; Female; Humans; Insulin; Janus Kinase 2; Lactation; Leptin; Male; Obesity; Rats; Rats, Wistar; Resveratrol; Stilbenes; Weaning | 2014 |
Resveratrol protects against cigarette smoke-induced oxidative damage and pulmonary inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Catalase; Female; Gene Expression; Glutathione Peroxidase; Heme Oxygenase-1; Interleukin-6; Lung; Lung Injury; Membrane Proteins; Mice; Mice, Inbred Strains; NF-kappa B; Nicotiana; Pneumonia; Resveratrol; Smoke; Stilbenes; Superoxide Dismutase; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Blotting, Western; Carbon; Cell Line; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Humans; Indican; Isothiocyanates; Lipid Peroxidation; Liver; Male; NF-E2-Related Factor 2; Oxides; Quercetin; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Sulfotransferases; Sulfoxides | 2014 |
Spinal SIRT1 activation attenuates neuropathic pain in mice.
Topics: Animals; Down-Regulation; Hyperalgesia; Male; Mice; Mice, Inbred Strains; NAD; Neuralgia; Niacinamide; Resveratrol; Sirtuin 1; Spinal Cord; Stilbenes | 2014 |
FeCl3-promoted and ultrasound-assisted synthesis of resveratrol O-derived glycoside analogs.
Topics: Catalysis; Chemistry Techniques, Synthetic; Chlorides; Ferric Compounds; Glycosides; Oxygen; Palladium; Resveratrol; Stilbenes; Ultrasonics | 2015 |
Inhibition of cancer derived cell lines proliferation by synthesized hydroxylated stilbenes and new ferrocenyl-stilbene analogs. Comparison with resveratrol.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Epithelial Cells; Ferrous Compounds; Hep G2 Cells; Humans; Intestinal Mucosa; Resveratrol; Stilbenes | 2014 |
Enhancement of phenolics, resveratrol and antioxidant activity by nitrogen enrichment in cell suspension culture of Vitis vinifera.
Topics: Antioxidants; Biomass; Cells, Cultured; Free Radical Scavengers; Nitrates; Nitrogen; Phenols; Resveratrol; Stilbenes; Vitis | 2014 |
Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells.
Topics: Acetylation; Cell Differentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Enzyme Activation; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; I-kappa B Kinase; Imidazoles; Interleukin-1beta; Mesenchymal Stem Cells; NF-kappa B; Niacinamide; Quinoxalines; Resveratrol; Signal Transduction; Sirtuin 1; SOX9 Transcription Factor; Stilbenes | 2014 |
Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice.
Topics: Adenylate Kinase; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Resveratrol; rho-Associated Kinases; rhoA GTP-Binding Protein; Stilbenes | 2014 |
Isolation, characterization, spectroscopic properties and quantum chemical computations of an important phytoalexin resveratrol as antioxidant component from Vitis labrusca L. and their chemical compositions.
Topics: Antioxidants; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Models, Molecular; Phytoalexins; Quantum Theory; Resveratrol; Sesquiterpenes; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes; Vitis | 2014 |
Biochemical and cellular evidence demonstrating AKT-1 as a binding partner for resveratrol targeting protein NQO2.
Topics: Carrier Proteins; Cell Line; Enzyme Activation; Gene Expression; Gene Knockdown Techniques; Humans; Hydrogen Bonding; Models, Molecular; Protein Binding; Protein Conformation; Protein Stability; Protein Transport; Proto-Oncogene Proteins c-akt; Quinone Reductases; Resveratrol; RNA Stability; Stilbenes | 2014 |
RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus biofilm inhibition by ursolic acid and resveratrol.
Topics: Anti-Infective Agents; Antioxidants; Bacterial Proteins; Biofilms; Biomarkers; Gene Expression Profiling; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Methicillin-Resistant Staphylococcus aureus; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Messenger; Staphylococcal Infections; Stilbenes; Triterpenes; Ursolic Acid | 2014 |
Resveratrol protects vascular smooth muscle cells against high glucose-induced oxidative stress and cell proliferation in vitro.
Topics: Animals; Biomarkers; Cell Cycle; Cell Proliferation; Cell Survival; Cells, Cultured; Cytoprotection; Extracellular Signal-Regulated MAP Kinases; Glucose; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Development of an in vitro periodontal biofilm model for assessing antimicrobial and host modulatory effects of bioactive molecules.
Topics: Aggregatibacter actinomycetemcomitans; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anti-Inflammatory Agents; Biofilms; Cell Line; Chlorhexidine; Coculture Techniques; Down-Regulation; Epithelial Cells; Fusobacterium nucleatum; Host-Pathogen Interactions; Humans; Inflammation Mediators; Interleukin-8; Keratinocytes; Microbial Consortia; Periodontal Diseases; Porphyromonas gingivalis; Resveratrol; RNA, Messenger; Saliva, Artificial; Stilbenes; Streptococcus mitis | 2014 |
Social deficits induced by peripubertal stress in rats are reversed by resveratrol.
Topics: Aging; Animals; Behavior, Animal; Cerebral Cortex; Enzyme Inhibitors; Exploratory Behavior; Fear; Female; Gyrus Cinguli; Male; Monoamine Oxidase; Prefrontal Cortex; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Social Behavior; Stilbenes; Stress, Psychological; Treatment Outcome | 2014 |
A role for peroxisome proliferator-activated receptor gamma in resveratrol-induced colon cancer cell apoptosis.
Topics: Anilides; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; PPAR gamma; Resveratrol; Rosiglitazone; S Phase Cell Cycle Checkpoints; Stilbenes; Thiazolidinediones | 2014 |
Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells.
Topics: Alcohol Oxidoreductases; Antineoplastic Agents; Breast Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Leupeptins; MCF-7 Cells; Phytotherapy; Plant Extracts; Resveratrol; RNA, Messenger; Stilbenes | 2014 |
Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Caloric Restriction; Creatine Kinase; Doxorubicin; Heart; Heat-Shock Proteins; L-Lactate Dehydrogenase; Male; Proteins; Rats; Rats, Inbred Strains; Resveratrol; Sequestosome-1 Protein; Stilbenes | 2014 |
Inhibition of STAT3 acetylation is associated with angiotesin renal fibrosis in the obstructed kidney.
Topics: Acetylation; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Fibrosis; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Phosphorylation; Rats; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2014 |
Impact of wines and wine constituents on cyclooxygenase-1, cyclooxygenase-2, and 5-lipoxygenase catalytic activity.
Topics: Arachidonate 5-Lipoxygenase; Catalysis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Flavonoids; Humans; Quercetin; Resveratrol; Stilbenes; Wine | 2014 |
Phytoestrogens induce differential effects on both normal and malignant human breast cells in vitro.
Topics: Apoptosis; Breast; Breast Neoplasms; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Genistein; Humans; In Situ Nick-End Labeling; MCF-7 Cells; Phytoestrogens; Quercetin; Resveratrol; Signal Transduction; Stilbenes | 2014 |
New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol.
Topics: Absorption, Physiological; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Chelating Agents; Clioquinol; Copper; Drug Design; Hydroxyl Radical; Mice; Oxidation-Reduction; Permeability; Protein Aggregates; Resveratrol; Small Molecule Libraries; Spectrophotometry, Ultraviolet; Stilbenes | 2014 |
Effect of resveratrol on hematological and biochemical alterations in rats exposed to fluoride.
Topics: Animals; Fluorides; Hematocrit; Leukocytes; Rats; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits ovarian cancer cell adhesion to peritoneal mesothelium in vitro by modulating the production of α5β1 integrins and hyaluronic acid.
Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Epithelial Cells; Epithelium; Female; Humans; Hyaluronic Acid; Integrin alpha5beta1; Ovarian Neoplasms; Peritoneum; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2014 |
Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetulus; Female; Gene Knockdown Techniques; Glucuronides; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Resveratrol; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Stilbenes | 2014 |
Compositional analysis of the fruiting body of transgenic Flammulina velutipes producing resveratrol.
Topics: Flammulina; Fruiting Bodies, Fungal; Genetic Engineering; Resveratrol; Stilbenes | 2014 |
Cytotoxicity of mitochondria-targeted resveratrol derivatives: interactions with respiratory chain complexes and ATP synthase.
Topics: Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Electron Transport; Hydrogen Peroxide; Mice; Microscopy, Fluorescence; Mitochondria; Oxygen Consumption; Proton-Translocating ATPases; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Proteomic identification of proteins differentially expressed in response to resveratrol treatment in middle cerebral artery occlusion stroke model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; Proteomics; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stroke; Transcriptome | 2014 |
Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1.
Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; DNA Helicases; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Poly-ADP-Ribose Binding Proteins; Protein Binding; Resveratrol; RNA Helicases; RNA Recognition Motif Proteins; Stilbenes; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitination | 2015 |
Resveratrol protects rabbit articular chondrocyte against sodium nitroprusside-induced apoptosis via scavenging ROS.
Topics: Animals; Apoptosis; Cartilage, Articular; Caspases; Cell Survival; Chondrocytes; Cytoskeleton; Free Radical Scavengers; Membrane Potential, Mitochondrial; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rabbits; Reactive Oxygen Species; Resveratrol; Sincalide; Stilbenes | 2014 |
Novel role of resveratrol: suppression of high-mobility group protein box 1 nucleocytoplasmic translocation by the upregulation of sirtuin 1 in sepsis-induced liver injury.
Topics: Acetylation; Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Nucleus; Cells, Cultured; Cytoplasm; Drug Evaluation, Preclinical; Gene Knockdown Techniques; Hepatocytes; HMGB1 Protein; Male; Molecular Targeted Therapy; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Sepsis; Sirtuin 1; Stilbenes; Translocation, Genetic; Up-Regulation | 2014 |
Quantification of the resveratrol analogs trans-2,3-dimethoxy-stilbene and trans-3,4-dimethoxystilbene in rat plasma: application to pre-clinical pharmacokinetic studies.
Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; Drug Stability; Male; Microsomes, Liver; Rats; Reproducibility of Results; Resveratrol; Stilbenes | 2014 |
Resveratrol metabolites have an antiproliferative effect on intestinal epithelial cancer cells.
Topics: Adenocarcinoma; Antioxidants; Apoptosis; Cell Cycle; Cell Proliferation; Humans; Intestinal Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2012 |
Piceid presents antiproliferative effects in intestinal epithelial Caco-2 cells, effects unrelated to resveratrol release.
Topics: Caco-2 Cells; Cell Cycle; Cell Proliferation; Epithelial Cells; Glucosides; Growth Inhibitors; Humans; Intestines; Resveratrol; Stilbenes | 2014 |
Resveratrol induced inhibition of Escherichia coli proceeds via membrane oxidation and independent of diffusible reactive oxygen species generation.
Topics: Bacterial Proteins; Catalase; Cell Wall; Escherichia coli; Escherichia coli Proteins; Gamma Rays; Glutathione; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Repressor Proteins; Resveratrol; Stilbenes; Superoxide Dismutase; Trans-Activators; Transcription Factors | 2014 |
Antifungal activity of resveratrol derivatives against Candida species.
Topics: Antifungal Agents; Benzofurans; Candida; Candida albicans; Microbial Sensitivity Tests; Molecular Structure; Resveratrol; Stereoisomerism; Stilbenes; Vitis | 2014 |
Resveratrol-loaded nanoparticles reduce oxidative stress induced by radiation or amyloid-beta in transgenic Caenorhabditis elegans.
Topics: Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Caenorhabditis elegans; Gamma Rays; Lipid Peroxidation; Nanoparticles; Oxidative Stress; Polyethylene Glycols; Resveratrol; Solubility; Stilbenes | 2014 |
Neuroprotective role of trans-resveratrol in a murine model of familial Alzheimer's disease.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Disease Models, Animal; Male; Memory Disorders; Memory, Short-Term; Mice, Transgenic; Neuroprotective Agents; Plaque, Amyloid; Presenilin-1; Recognition, Psychology; Resveratrol; Stilbenes | 2014 |
Resveratrol increases nephrin and podocin expression and alleviates renal damage in rats fed a high-fat diet.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Body Weight; Chemokine CCL2; Diet, High-Fat; Glucose Tolerance Test; Intracellular Signaling Peptides and Proteins; Kidney; Male; Malondialdehyde; Membrane Proteins; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2014 |
Imine resveratrol analogues: molecular design, Nrf2 activation and SAR analysis.
Topics: Antioxidants; Drug Design; Humans; Imines; MCF-7 Cells; NF-E2-Related Factor 2; Quantitative Structure-Activity Relationship; Response Elements; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Physiologically achievable doses of resveratrol enhance 3T3-L1 adipocyte differentiation.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Mice; PPAR gamma; Receptors, Glucocorticoid; Resveratrol; RNA, Messenger; RNA, Small Interfering; Stilbenes; Transcription Factors | 2015 |
Biosynthesis of methylated resveratrol analogs through the construction of an artificial biosynthetic pathway in E. coli.
Topics: Chromatography, High Pressure Liquid; Escherichia coli; Genetic Vectors; Mass Spectrometry; Methylation; Methyltransferases; Plant Proteins; Resveratrol; Sorghum; Stilbenes | 2014 |
Resveratrol is not compatible with a Fura-2-based assay for measuring intracellular Ca²⁺ signaling.
Topics: Calcium Signaling; Fluorescent Dyes; Fura-2; Resveratrol; Stilbenes | 2014 |
Content of resveratrol and glycoside and its contribution to the antioxidative capacity of Polygonum cuspidatum (Itadori) harvested in Kochi.
Topics: Antioxidants; Fallopia japonica; Glycosides; Plant Extracts; Plant Roots; Plant Stems; Resveratrol; Stilbenes | 2014 |
Effect of Robola and Cabernet Sauvignon extracts on platelet activating factor enzymes activity on U937 cells.
Topics: Atherosclerosis; Humans; Platelet Activating Factor; Resveratrol; Stilbenes; U937 Cells; Wine | 2014 |
A study of multi-ligand beta-lactoglobulin complex formation.
Topics: alpha-Tocopherol; Circular Dichroism; Folic Acid; Lactoglobulins; Protein Structure, Secondary; Resveratrol; Stilbenes | 2014 |
Antioxidative effects and percutaneous absorption of five polyphenols.
Topics: Administration, Cutaneous; Animals; Antioxidants; Biphenyl Compounds; Catechin; Chromans; Chromatography, High Pressure Liquid; Free Radical Scavengers; Picrates; Polyphenols; Quercetin; Resveratrol; Rutin; Skin; Skin Absorption; Stilbenes; Swine | 2014 |
Resveratrol protects against homocysteine-induced cell damage via cell stress response in neuroblastoma cells.
Topics: Analysis of Variance; Cell Death; Cell Line, Tumor; DNA Damage; Gene Expression Regulation, Neoplastic; Homocysteine; HSP70 Heat-Shock Proteins; Humans; Microscopy, Confocal; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Interferon gamma induced by resveratrol analog, HS-1793, reverses the properties of tumor associated macrophages.
Topics: Animals; Cell Line, Tumor; Cell Movement; Female; Interferon-gamma; Macrophages; Mice; Mice, Inbred C3H; Naphthols; Neoplasm Invasiveness; Neoplasms; Resorcinols; Resveratrol; Stilbenes | 2014 |
Probing treatment response of glutaminolytic prostate cancer cells to natural drugs with hyperpolarized [5-(13) C]glutamine.
Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Biomarkers, Tumor; Carbon Isotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Contrast Media; Enzyme-Linked Immunosorbent Assay; Gadolinium; Glutamine; Heterocyclic Compounds; Humans; In Vitro Techniques; Isothiocyanates; Magnetic Resonance Spectroscopy; Male; Organometallic Compounds; Phenotype; Prostatic Neoplasms; Resveratrol; Stilbenes; Sulfoxides | 2015 |
Synergic effects of artemisinin and resveratrol in cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Artemisinins; Cell Movement; Cell Proliferation; Drug Synergism; Flow Cytometry; HeLa Cells; Hep G2 Cells; Humans; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Administration of the resveratrol analogues isorhapontigenin and heyneanol-A protects mice hematopoietic cells against irradiation injuries.
Topics: Animals; Bone Marrow Cells; Cell Lineage; Cell Survival; Colony-Forming Units Assay; Cytoprotection; Flow Cytometry; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred C57BL; Radiation, Ionizing; Resveratrol; Stilbenes; Superoxide Dismutase; Time Factors | 2014 |
Resveratrol inhibits proliferation in human colorectal carcinoma cells by inducing G1/S‑phase cell cycle arrest and apoptosis through caspase/cyclin‑CDK pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Caspase 7; Caspase 9; Caspases; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Poly(ADP-ribose) Polymerases; Proliferating Cell Nuclear Antigen; Resveratrol; S Phase Cell Cycle Checkpoints; Stilbenes | 2014 |
Cardiac energy metabolism and oxidative stress biomarkers in diabetic rat treated with resveratrol.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Energy Intake; Energy Metabolism; Fatty Acids, Nonesterified; Glutathione; Male; Myocardium; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
MALDI mass spectrometry imaging for the simultaneous location of resveratrol, pterostilbene and viniferins on grapevine leaves.
Topics: Oomycetes; Plant Diseases; Plant Leaves; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Vitis | 2014 |
Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Antioxidants; Body Composition; Double-Blind Method; Human Growth Hormone; Mice; Muscles; Obesity; Resveratrol; Signal Transduction; Sirtuin 1; STAT5 Transcription Factor; Stilbenes | 2014 |
Protective effect of polydatin, a natural precursor of resveratrol, against cisplatin-induced toxicity in rats.
Topics: Animals; Antioxidants; Catalase; Cisplatin; DNA Damage; Erythrocytes; Glucosides; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2014 |
[Enhanced sensitivity of leukemia cell line KG-1a to activated immune cell-mediated cytolysis after treated with resveratrol].
Topics: Cell Line, Tumor; Cell Proliferation; Humans; Leukemia; Leukocytes, Mononuclear; Male; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor, Member 10c; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand | 2014 |
Immunomodulatory effects of high-protein diet with resveratrol supplementation on radiation-induced acute-phase inflammation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Deoxyguanosine; Diet; Dietary Proteins; Dietary Supplements; Female; Immune System; Inflammation; Leukocyte Count; Lipid Metabolism; Lipids; Neoplasms; Phytotherapy; Plant Extracts; Platelet Count; Radiation Injuries, Experimental; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
Resveratrol ameliorates motor neuron degeneration and improves survival in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Behavior, Animal; Disease Models, Animal; Female; Lipid Peroxidation; Lumbar Vertebrae; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Motor Neurons; Muscle, Skeletal; Neurodegenerative Diseases; Oxidative Stress; Resveratrol; Spinal Cord; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2014 |
Amelioration of doxorubicin‑induced cardiotoxicity by resveratrol.
Topics: Animals; Antioxidants; Cardiotoxicity; Creatine Kinase; Doxorubicin; Glutathione; Heart; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocytes, Cardiac; Oxidative Stress; Plant Extracts; Polyphenols; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells.
Topics: Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; ErbB Receptors; Humans; Keratinocytes; Phosphorylation; Resveratrol; STAT3 Transcription Factor; Stilbenes; Structure-Activity Relationship; Sulfides | 2014 |
Pharmacological upregulation of PGC1α in oligodendrocytes: implications for Huntington's Disease.
Topics: Animals; Cell Differentiation; Cells, Cultured; Heterocyclic Compounds, 4 or More Rings; Huntington Disease; Mice; Mutation; Oligodendroglia; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Serotonin Plasma Membrane Transport Proteins; Sirtuin 1; Stilbenes; Transcription Factors; Up-Regulation | 2013 |
Resveratrol mitigate structural changes and hepatic stellate cell activation in N'-nitrosodimethylamine-induced liver fibrosis via restraining oxidative damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Dimethylnitrosamine; Electrophoresis, Gel, Two-Dimensional; Hepatic Stellate Cells; Liver Cirrhosis; Male; Oxidative Stress; Rats; Resveratrol; Stilbenes | 2014 |
AMP-activated protein kinase mediates the antioxidant effects of resveratrol through regulation of the transcription factor FoxO1.
Topics: Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Animals; Antioxidants; Forkhead Box Protein O1; Forkhead Transcription Factors; HEK293 Cells; Hep G2 Cells; Humans; Mice; Phosphorylation; Protein Processing, Post-Translational; Protein Stability; Reactive Oxygen Species; Resveratrol; Stilbenes; Transcription, Genetic; Transcriptional Activation | 2014 |
New inhibitors of the Kvβ2 subunit from mammalian Kv1 potassium channels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Brain; Catechols; Cortisone; Kinetics; NADP; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Binding; Rats; Resveratrol; Rutin; Shaker Superfamily of Potassium Channels; Stilbenes; Valproic Acid | 2014 |
Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway.
Topics: Autophagy; beta Catenin; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Neoplastic Stem Cells; Resveratrol; Signal Transduction; Stilbenes; Wnt Proteins | 2014 |
[The antagonistic effect of folic acid and resveratrol on cleft palate in mice induced by TCDD].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Fetus; Folic Acid; Humans; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Pregnancy; Random Allocation; Resveratrol; Stilbenes; Teratogens | 2013 |
A novel anti‑cancer effect of resveratrol: reversal of epithelial‑mesenchymal transition in prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Movement; Cell Survival; Epithelial-Mesenchymal Transition; Hedgehog Proteins; Humans; Lipopolysaccharides; Male; Prostatic Neoplasms; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Transcription Factors; Vimentin; Zinc Finger Protein GLI1 | 2014 |
Inhibition of HDAC increases the senescence induced by natural polyphenols in glioma cells.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Cell Line, Tumor; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Drug Screening Assays, Antitumor; Drug Synergism; Glioma; Histone Deacetylase Inhibitors; Humans; Quercetin; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Resveratrol induces luminal apoptosis of human colorectal cancer HCT116 cells in three-dimensional culture.
Topics: Apoptosis; HCT116 Cells; Humans; Phosphodiesterase 4 Inhibitors; Resveratrol; Stilbenes | 2014 |
Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition.
Topics: Animals; Antioxidants; Apoptosis; Boronic Acids; Bortezomib; CHO Cells; Cricetinae; Cricetulus; Membrane Potential, Mitochondrial; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrazines; Reactive Oxygen Species; Resveratrol; Stilbenes; Ubiquitination | 2014 |
Effect of resveratrol on behavioral performance of streptozotocin-induced diabetic mice in anxiety tests.
Topics: Adaptation, Psychological; Animals; Anti-Anxiety Agents; Anticarcinogenic Agents; Antioxidants; Anxiety; Behavior, Animal; Defecation; Diabetes Mellitus, Experimental; Grooming; Male; Mice; Motor Activity; Resveratrol; Stilbenes; Streptozocin; Time Factors; Urination | 2014 |
In vitro tests of resveratrol radiomodifying effect on rhabdomyosarcoma cells by comet assay.
Topics: Cell Line, Tumor; Cell Survival; Comet Assay; Cytoprotection; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Radiation-Sensitizing Agents; Resveratrol; Rhabdomyosarcoma; Stilbenes | 2014 |
Resveratrol prevents cigarette smoke-induced keratinocytes damage.
Topics: Antioxidants; Cell Line; Humans; Keratinocytes; Methionine Sulfoxide Reductases; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Resveratrol; Smoke; Stilbenes; Tobacco Products | 2014 |
Investigating the effects of resveratrol on chronically ischemic myocardium in a swine model of metabolic syndrome: a proteomics analysis.
Topics: Animals; Antioxidants; Biomarkers; Cell Death; Cholesterol, Dietary; Coronary Vessels; Dietary Supplements; Disease Models, Animal; Heart; Male; Metabolic Syndrome; Mitochondria; Myocardial Ischemia; Myocardium; Phytotherapy; Plant Extracts; Proteins; Proteomics; Resveratrol; Signal Transduction; Stilbenes; Swine | 2015 |
Resveratrol prevents the development of choroidal neovascularization by modulating AMP-activated protein kinase in macrophages and other cell types.
Topics: AMP-Activated Protein Kinases; Animals; Cell Movement; Choroidal Neovascularization; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Real-Time Polymerase Chain Reaction; Resveratrol; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2014 |
Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a rat periodontitis model.
Topics: 8-Hydroxy-2'-Deoxyguanosine; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Bone Resorption; Cytokines; Deoxyguanosine; Disease Models, Animal; Gingiva; Inflammation; Male; NF-E2-Related Factor 2; Nitric Oxide; Oxidative Stress; Periodontitis; Random Allocation; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Tyrosine | 2014 |
AMPK activation prevents prenatal stress-induced cognitive impairment: modulation of mitochondrial content and oxidative stress.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Line; Cognition; Cognitive Dysfunction; Enzyme Activation; Female; Glutathione; Hippocampus; Humans; Male; Mitochondria; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress, Psychological | 2014 |
Resveratrol modulates mitochondria dynamics in replicative senescent yeast cells.
Topics: Mitochondrial Dynamics; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Vasodilator Agents | 2014 |
In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery.
Topics: Animals; Antineoplastic Agents; Brain; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Injections, Intraperitoneal; Lipids; Nanoparticles; Rats; Rats, Wistar; Resveratrol; Stilbenes; Structure-Activity Relationship; Tissue Distribution | 2014 |
Resveratrol: inhibitory effects on metastatic cell behaviors and voltage-gated Na⁺ channel activity in rat prostate cancer in vitro.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Male; Neoplasm Metastasis; Prostatic Neoplasms; Rats; Resveratrol; Sodium Channel Blockers; Sodium Channels; Stilbenes; Tetrodotoxin | 2014 |
A self-microemulsifying drug delivery system to overcome intestinal resveratrol toxicity and presystemic metabolism.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Caprylates; Castor Oil; Chemistry, Pharmaceutical; Drug Carriers; Emulsions; Glycerides; Humans; Intestinal Absorption; Jejunum; Male; Multidrug Resistance-Associated Proteins; Permeability; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes; Surface-Active Agents; Technology, Pharmaceutical; Viscosity | 2014 |
Investigations of curcumin and resveratrol on neurite outgrowth: perspectives on spinal muscular atrophy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Motor Neurons; Muscular Atrophy, Spinal; Neurites; PC12 Cells; Rats; Resveratrol; Stilbenes | 2014 |
The rescuable function and mechanism of resveratrol on As₂O₃-induced hERG K⁺ channel deficiency.
Topics: Action Potentials; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Blotting, Western; Cardiotonic Agents; Cardiotoxicity; Down-Regulation; Endoplasmic Reticulum Stress; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart Ventricles; HEK293 Cells; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques; Resveratrol; Stilbenes | 2014 |
Pharmacological activation of AMPK ameliorates perivascular adipose/endothelial dysfunction in a manner interdependent on AMPK and SIRT1.
Topics: Adipokines; Adipose Tissue; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Aorta; Culture Media, Conditioned; Diet; Fructose; Metformin; NF-kappa B; Palmitic Acid; Rats; Resveratrol; Ribonucleotides; Sirtuin 1; Sodium Salicylate; Stilbenes; Vasodilation | 2014 |
Resveratrol is active against Leishmania amazonensis: in vitro effect of its association with Amphotericin B.
Topics: Amphotericin B; Antiprotozoal Agents; Computational Biology; Drug Synergism; Leishmania; Magnetic Resonance Spectroscopy; Resveratrol; Ristocetin; Stilbenes | 2014 |
Novel resveratrol and 5-fluorouracil coencapsulated in PEGylated nanoliposomes improve chemotherapeutic efficacy of combination against head and neck squamous cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Fluorouracil; Head and Neck Neoplasms; Humans; Liposomes; Nanoparticles; Polyethylene Glycols; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes | 2014 |
Resveratrol suppresses oxidised low-density lipoprotein-induced macrophage apoptosis through inhibition of intracellular reactive oxygen species generation, LOX-1, and the p38 MAPK pathway.
Topics: Animals; Apoptosis; Cell Line; Lipoproteins, LDL; Macrophages; Mice; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Resveratrol; Scavenger Receptors, Class E; Stilbenes | 2014 |
Resveratrol attenuates hypoxia/reoxygenation‑induced Ca2+ overload by inhibiting the Wnt5a/Frizzled‑2 pathway in rat H9c2 cells.
Topics: Animals; Apoptosis; Calcium; Cardiotonic Agents; Cell Hypoxia; Cell Line; Drug Evaluation, Preclinical; Frizzled Receptors; Gene Expression; Myocardial Reperfusion Injury; Rats; Resveratrol; Stilbenes; Wnt Proteins; Wnt Signaling Pathway; Wnt-5a Protein | 2014 |
Treatment of FANCA cells with resveratrol and N-acetylcysteine: a comparative study.
Topics: Acetylcysteine; Antioxidants; Cells, Cultured; Drug Evaluation, Preclinical; Fanconi Anemia; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men.
Topics: Aged; Case-Control Studies; Dietary Supplements; Exercise; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Male; Middle Aged; Muscle, Skeletal; Neovascularization, Physiologic; Resveratrol; Stilbenes; Thrombospondin 1; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2014 |
Arsenic trioxide and resveratrol show synergistic anti-leukemia activity and neutralized cardiotoxicity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Leukemia, Promyelocytic, Acute; Myocytes, Cardiac; Neoplasm Proteins; Oxides; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2014 |
Resveratrol, a natural antioxidant, has a protective effect on liver injury induced by inorganic arsenic exposure.
Topics: Animals; Antioxidants; Arsenic; Arsenic Trioxide; Arsenicals; Cats; Environmental Exposure; Glutathione; Liver; Liver Diseases; Malondialdehyde; Oxidative Stress; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
Chemical and sensory characterisation of Sangiovese red wines: comparison between biodynamic and organic management.
Topics: Biogenic Amines; Catechin; Humans; Phenols; Polyphenols; Resveratrol; Stilbenes; Volatile Organic Compounds; Wine | 2015 |
Nutraceutical delivery systems: resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification.
Topics: Dietary Supplements; Emulsions; Resveratrol; Seeds; Stilbenes; Vitis | 2015 |
Investigation of the absorption of resveratrol oligomers in the Caco-2 cellular model of intestinal absorption.
Topics: Biological Transport; Caco-2 Cells; Humans; Intestinal Absorption; Polyphenols; Resveratrol; Stilbenes; Wine | 2015 |
The effect of resveratrol and its methylthio-derivatives on NF-κB and AP-1 signaling pathways in HaCaT keratinocytes.
Topics: Blotting, Western; Cell Line; Cyclooxygenase 2; Enzyme-Linked Immunosorbent Assay; Humans; Keratinocytes; NF-kappa B; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-fos; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor AP-1 | 2014 |
Therapeutic potential of resveratrol in diabetic complications: In vitro and in vivo studies.
Topics: Aldehyde Reductase; Animals; Cataract; Cattle; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Glycation End Products, Advanced; Imidazolidines; Inhibitory Concentration 50; Kidney Function Tests; Lens, Crystalline; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2014 |
Resveratrol attenuates methylglyoxal-induced mitochondrial dysfunction and apoptosis by Sestrin2 induction.
Topics: Adenoviridae; Animals; Apoptosis; Glycation End Products, Advanced; Hep G2 Cells; Humans; Male; Mice; Mice, Inbred ICR; Mitochondria; Nuclear Proteins; Pyruvaldehyde; Reactive Oxygen Species; Resveratrol; Stilbenes | 2014 |
[Investigation of properties of the resveratrol-beta-cyclodextrin inclusion complex by drug-protein interaction spectra and molecular modeling].
Topics: Animals; beta-Cyclodextrins; Cattle; Lactoferrin; Magnetic Resonance Spectroscopy; Models, Molecular; Resveratrol; Stilbenes | 2014 |
Studies of the in vitro antibacterial activities of several polyphenols against clinical isolates of methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacteremia; Drug Synergism; Humans; Luteolin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Polyphenols; Quercetin; Resveratrol; Staphylococcal Infections; Stilbenes | 2014 |
Resveratrol preserves mitochondrial function, stimulates mitochondrial biogenesis, and attenuates oxidative stress in regulatory T cells of mice fed a high-fat diet.
Topics: Animals; Antioxidants; Apoptosis; Diet, High-Fat; Drug Evaluation, Preclinical; Male; Membrane Potential, Mitochondrial; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Turnover; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; T-Lymphocytes, Regulatory | 2014 |
Cytotoxicity studies of novel combretastatin and pterostilbene derivatives.
Topics: Bibenzyls; Cell Death; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Resveratrol; Stilbenes | 2014 |
Resveratrol enhanced FOXO3 phosphorylation via synergetic activation of SIRT1 and PI3K/Akt signaling to improve the effects of exercise in elderly rat hearts.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Biopsy; Blotting, Western; Carrier Proteins; Forkhead Box Protein O3; Forkhead Transcription Factors; In Situ Nick-End Labeling; Myocardium; Oncogene Protein v-akt; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Resveratrol; Ribonucleotide Reductases; Signal Transduction; Sirtuin 1; Stilbenes | 2014 |
Antioxidants successfully reduce ROS production in propionic acidemia fibroblasts.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Antioxidants; Chromans; Fibroblasts; Gene Expression; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Humans; Methylmalonyl-CoA Decarboxylase; Mitochondria; Mutation; Organophosphorus Compounds; Primary Cell Culture; Propionic Acidemia; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Ubiquinone | 2014 |
Resveratrol protects against experimental induced Reye's syndrome by prohibition of oxidative stress and restoration of complex I activity.
Topics: Ammonia; Animals; Antioxidants; Electron Transport Complex I; Fatty Acids, Monounsaturated; Malondialdehyde; Membrane Transport Proteins; Oxidative Stress; Prothrombin; Rats, Wistar; Resveratrol; Reye Syndrome; Serum Albumin; Serum Albumin, Human; Stilbenes; Transaminases | 2014 |
Resveratrol increases the bone marrow hematopoietic stem and progenitor cell capacity.
Topics: Animals; Antioxidants; Biomarkers; Bone Marrow Cells; Cell Proliferation; Gamma Rays; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Injections, Intraperitoneal; Leukocyte Common Antigens; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Whole-Body Irradiation | 2014 |
Ameliorative effect of resveratrol against fluoride-induced alteration of thyroid function in male wistar rats.
Topics: Animals; Fluorides; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Thyroid Gland; Thyroid Hormones | 2014 |
An anti-inflammatory cell-free collagen/resveratrol scaffold for repairing osteochondral defects in rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage Diseases; Cell-Free System; Combined Modality Therapy; Drug Implants; Equipment Design; Equipment Failure Analysis; Guided Tissue Regeneration; Materials Testing; Rabbits; Resveratrol; Stilbenes; Tissue Scaffolds; Treatment Outcome | 2014 |
The effect of resveratrol and its methylthio-derivatives on the Nrf2-ARE pathway in mouse epidermis and HaCaT keratinocytes.
Topics: Animals; Antioxidant Response Elements; Blotting, Western; Cell Line; Cell Nucleus; Cytosol; Epidermis; Female; Glutathione Transferase; Humans; Isoenzymes; Keratinocytes; Mice; NF-E2-Related Factor 2; Protein Binding; Protein Transport; Quinone Reductases; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Resveratrol synthesis under natural conditions and after UV-C irradiation in berry skin is associated with berry development stages in 'Beihong' (V. vinifera×V. amurensis).
Topics: Acyltransferases; Gene Expression; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2015 |
[Effects of activating silent information regulator 1 on early myocardial damage in severely burned rats].
Topics: Animals; Antioxidants; Apoptosis; Burns; Caspase 3; Edema; Interleukin-1beta; Male; Myocardium; Myocytes, Cardiac; Rats; Resveratrol; RNA, Messenger; Serum; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2014 |
Resveratrol induces the expression of interleukin-10 and brain-derived neurotrophic factor in BV2 microglia under hypoxia.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cell Line; Interleukin-10; Mice; Microglia; NF-kappa B; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2014 |
In vitro antiviral effects and 3D QSAR study of resveratrol derivatives as potent inhibitors of influenza H1N1 neuraminidase.
Topics: Animals; Antiviral Agents; Cell Line; Dogs; Drug Design; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Molecular Docking Simulation; Neuraminidase; Orthomyxoviridae Infections; Quantitative Structure-Activity Relationship; Resveratrol; Stilbenes | 2015 |
Effect of resveratrol on proliferation and apoptosis of human pancreatic cancer MIA PaCa-2 cells may involve inhibition of the Hedgehog signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fluorouracil; Hedgehog Proteins; Humans; Pancreatic Neoplasms; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Resveratrol; Signal Transduction; Smoothened Receptor; Stilbenes | 2014 |
Structural basis of ConM binding with resveratrol, an anti-inflammatory and antioxidant polyphenol.
Topics: Anti-Inflammatory Agents; Antioxidants; Binding Sites; Biphenyl Compounds; Canavalia; Crystallography, X-Ray; Free Radical Scavengers; Glycosylation; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Picrates; Plant Lectins; Polyphenols; Protein Binding; Protein Structure, Secondary; Quercetin; Resveratrol; Stilbenes | 2015 |
Resveratrol ameliorates low shear stress‑induced oxidative stress by suppressing ERK/eNOS‑Thr495 in endothelial cells.
Topics: Antioxidants; Atherosclerosis; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Shear Strength; Stilbenes; Threonine | 2014 |
Isolation and identification of 2,4,6-trihydroxyphenanthrene as a byproduct of trans-resveratrol photochemical isomerization and electrocyclization.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Isomerism; Magnetic Resonance Spectroscopy; Phenanthrenes; Photochemical Processes; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2014 |
Resveratrol protects neurons and the myocardium by reducing oxidative stress and ameliorating mitochondria damage in a cerebral ischemia rat model.
Topics: Animals; Apoptosis; Brain Ischemia; Cardiotonic Agents; Disease Models, Animal; Heart; Male; Membrane Potential, Mitochondrial; Mitochondria; Myocardium; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
Preparation and optimization of resveratrol nanosuspensions by antisolvent precipitation using Box-Behnken design.
Topics: Colloids; Computer Simulation; Diffusion; Drug Compounding; Drug Design; Drug Stability; Fractional Precipitation; Models, Chemical; Nanocapsules; Particle Size; Resveratrol; Solubility; Solvents; Stilbenes; Surface-Active Agents | 2015 |
Novel resveratrol analogues attenuate renal ischemic injury in rats.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Aminophenols; Animals; Apoptosis; Drug Evaluation, Preclinical; Hydrazones; Kidney; Male; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2015 |
Alteration of splice site selection in the LMNA gene and inhibition of progerin production via AMPK activation.
Topics: Alternative Splicing; AMP-Activated Protein Kinases; Animals; Berberine; DNA, Mitochondrial; Enzyme Activation; Exons; Gene Expression Regulation; Humans; Lamin Type A; Metformin; Models, Biological; Mutation; Nuclear Proteins; Oxidative Phosphorylation; Phosphorylation; Point Mutation; Progeria; Resveratrol; RNA-Binding Proteins; Serine-Arginine Splicing Factors; Stilbenes | 2014 |
Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway.
Topics: Animals; Cell Line; Disease Models, Animal; Epithelial-Mesenchymal Transition; Extracellular Matrix; Fibrosis; Hedgehog Proteins; Kidney; Kidney Tubules; Male; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Resveratrol; Signal Transduction; Smoothened Receptor; Stilbenes; Transforming Growth Factor beta1; Ureteral Obstruction | 2014 |
Resveratrol synergistically enhances the effect of etoposide in HNSCC cell lines.
Topics: Analysis of Variance; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Flow Cytometry; Head and Neck Neoplasms; Humans; Reference Values; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes | 2014 |
Effect of chitosan concentration on PLGA microcapsules for controlled release and stability of resveratrol.
Topics: Capsules; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Humans; Lactic Acid; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; Stilbenes | 2015 |
Pre-formulation studies of resveratrol.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Blood Proteins; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; Humans; Hydrogen-Ion Concentration; Male; Pharmaceutical Solutions; Protein Binding; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Solvents; Species Specificity; Stilbenes | 2015 |
Resveratrol supplementation restores high-fat diet-induced insulin secretion dysfunction by increasing mitochondrial function in islet.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fats; Electron Transport; Gene Expression Regulation; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
AMP-activated protein kinase activation protects gastric epithelial cells from Helicobacter pylori-induced apoptosis.
Topics: AMP-Activated Protein Kinases; Apoptosis; Biphenyl Compounds; Cell Line; Cell Survival; Cells, Cultured; Enzyme Activation; Epithelial Cells; Gastric Mucosa; Gene Expression; Helicobacter pylori; Host-Pathogen Interactions; Humans; MAP Kinase Kinase Kinases; Pyrones; Resveratrol; RNA, Small Interfering; Stilbenes; Thiophenes | 2014 |
Synthesis of glycosides of resveratrol, pterostilbene, and piceatannol, and their anti-oxidant, anti-allergic, and neuroprotective activities.
Topics: Animals; Anti-Allergic Agents; Biphenyl Compounds; Cell Line; Chemistry Techniques, Synthetic; Free Radical Scavengers; Glycosides; Histamine Release; Male; Neuroprotective Agents; Phosphodiesterase Inhibitors; Picrates; Rats; Resveratrol; Stilbenes | 2014 |
Protective effect of resveratrol on fluoride induced alteration in protein and nucleic acid metabolism, DNA damage and biogenic amines in rat brain.
Topics: Animals; Antioxidants; Biogenic Amines; Body Weight; Brain; DNA Damage; Fluorides; Gene Expression Regulation, Enzymologic; Male; Neuroprotective Agents; Nucleic Acids; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2014 |
Regulation by resveratrol of prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts.
Topics: 3T3 Cells; Animals; Anthracenes; Dinoprostone; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Resveratrol ameliorates lipopolysaccharide-induced epithelial mesenchymal transition and pulmonary fibrosis through suppression of oxidative stress and transforming growth factor-β1 signaling.
Topics: Animals; Catalase; Collagen Type I; Disease Models, Animal; Epithelial-Mesenchymal Transition; Lipopolysaccharides; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; Pulmonary Fibrosis; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase; Transforming Growth Factor beta1 | 2015 |
The interplay between apoptosis, mitophagy and mitochondrial biogenesis induced by resveratrol can determine activated hepatic stellate cells death or survival.
Topics: Animals; Antioxidants; Apoptosis; Cell Line; Hepatic Stellate Cells; Mice; Mitophagy; Organelle Biogenesis; Resveratrol; Stilbenes | 2015 |
Resveratrol affects histone 3 lysine 27 methylation of vessels and blood biomarkers in DOCA salt-induced hypertension.
Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Blood Vessels; Desoxycorticosterone Acetate; Endothelium, Vascular; Fluorescent Antibody Technique; Histones; Hydrogen Sulfide; Hypertension; Lysine; Male; Methylation; Nitrites; Rats, Wistar; Renal Artery; Resveratrol; Stilbenes; Systole; Vasodilation | 2015 |
Oligostilbenoids from the heartwood of N. Heimii: role of non-covalent association in their biogenesis.
Topics: Dimerization; Dipterocarpaceae; Magnetic Resonance Spectroscopy; Molecular Conformation; Resveratrol; Stereoisomerism; Stilbenes; Thermodynamics | 2015 |
Variability in chemical composition of Vitis vinifera cv Mencía from different geographic areas and vintages in Ribeira Sacra (NW Spain).
Topics: Anthocyanins; Chromatography, High Pressure Liquid; Flavonols; Gas Chromatography-Mass Spectrometry; Geography; Phenols; Polyphenols; Resveratrol; Spain; Stilbenes; Vitis; Wine | 2015 |
High-fructose corn syrup-induced hepatic dysfunction in rats: improving effect of resveratrol.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Enzyme Activation; Fatty Acid Synthase, Type I; Gene Expression; High Fructose Corn Syrup; Insulin; Insulin Receptor Substrate Proteins; Liver; Male; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Stilbenes; Triglycerides | 2015 |
Resveratrol Derivative, 3,3',4,4'-Tetrahydroxy-trans-Stilbene, Retards Senescence of Mesothelial Cells via Hormetic-Like Prooxidative Mechanism.
Topics: Antioxidants; beta-Galactosidase; Catalase; Cell Growth Processes; Cell Proliferation; Cells, Cultured; Cellular Senescence; DNA Damage; Glutathione; Humans; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peritoneum; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Enzymatic Biosynthesis of Novel Resveratrol Glucoside and Glycoside Derivatives.
Topics: Bacillus; Carbohydrates; Cloning, Molecular; Cytosol; Gene Expression; Glucuronosyltransferase; Glycosides; Recombinant Proteins; Resveratrol; Stilbenes | 2014 |
Resveratrol reversal.
Topics: Aged; Antioxidants; Diet; Female; Follow-Up Studies; Health Status; Humans; Longevity; Male; Middle Aged; Plant Extracts; Resveratrol; Stilbenes | 2014 |
Differential regulation of estrogen receptors α and β by 4-(E)-{(4-hydroxyphenylimino)-methylbenzene,1,2-diol}, a novel resveratrol analog.
Topics: Antineoplastic Agents; Catechols; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Molecular Docking Simulation; para-Aminobenzoates; Proto-Oncogene Proteins c-myc; Resveratrol; RNA, Messenger; Schiff Bases; Stilbenes | 2014 |
Resveratrol ameliorates mitochondrial dysfunction but increases the risk of hypoglycemia following hemorrhagic shock.
Topics: Animals; Blood Glucose; Corticosterone; Glucagon; Glucagon-Like Peptide 1; Hypoglycemia; Insulin; Insulin Resistance; Kidney; Male; Mitochondria; Mitochondria, Liver; Rats, Long-Evans; Reactive Oxygen Species; Resuscitation; Resveratrol; Shock, Hemorrhagic; Stilbenes | 2014 |
Can drinking wine really promote longevity? Recent evidence shows the antioxidant resveratrol in wine does not offer a health boost.
Topics: Antioxidants; Cardiovascular Diseases; Dietary Supplements; Humans; Longevity; Resveratrol; Stilbenes; Wine | 2014 |
Resveratrol regulates naïve CD 8+ T-cell proliferation by upregulating IFN-γ-induced tryptophanyl-tRNA synthetase expression.
Topics: CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Humans; Interferon-gamma; Resveratrol; Stilbenes; Tryptophan-tRNA Ligase; Up-Regulation | 2015 |
Prevention of cyclophosphamide-induced hemorrhagic cystitis by resveratrol: a comparative experimental study with mesna.
Topics: Animals; Biomarkers; Cyclophosphamide; Cystitis; Hemorrhage; Immunoenzyme Techniques; In Situ Nick-End Labeling; Male; Mesna; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits sodium/iodide symporter gene expression and function in rat thyroid cells.
Topics: Animals; Antioxidants; Cell Line; Down-Regulation; Iodides; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Sodium; Stilbenes; Symporters; Thyroid Gland | 2014 |
The effect of the SIRT1 2827 A>G polymorphism, resveratrol, exercise, age and occupation in Turkish population with cardiovascular disease.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; DNA; Exercise; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Occupations; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Resveratrol; Sirtuin 1; Stilbenes; Turkey | 2015 |
Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinogens; Celecoxib; Chemoprevention; Drug Synergism; Female; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Methylnitrosourea; Pyrazoles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Sulfonamides | 2014 |
Analysis of phenolics in wine by high performance thin-layer chromatography with gradient elution and high resolution plate imaging.
Topics: Antioxidants; Caffeic Acids; Chromatography, Thin Layer; Gallic Acid; Phenols; Resveratrol; Rutin; Stilbenes; Wine | 2015 |
Anti-stress action of an orally-given combination of resveratrol, β-glucan, and vitamin C.
Topics: Administration, Oral; Animals; Ascorbic Acid; beta-Glucans; Mice; Resveratrol; Stilbenes | 2014 |
A combined experimental and computational study of Vam3, a derivative of resveratrol, and Syk interaction.
Topics: Adenosine Triphosphate; Benzofurans; Crystallography, X-Ray; Dimerization; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Protein Conformation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Resveratrol; Stilbenes; Structure-Activity Relationship; Syk Kinase; Vitis | 2014 |
Resveratrol prevents social deficits in animal model of autism induced by valproic acid.
Topics: Animals; Anti-Inflammatory Agents; Autistic Disorder; Female; Male; Maternal Exposure; Molecular Dynamics Simulation; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Resveratrol; Social Skills; Stilbenes; Valproic Acid | 2014 |
In vitro protective effects of resveratrol against oxidative damage in human erythrocytes.
Topics: Antioxidants; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Hemolysis; Humans; Hypochlorous Acid; Lipid Bilayers; Microscopy; Microscopy, Electron, Scanning; Molecular Structure; Oxidants; Oxidative Stress; Phosphatidylethanolamines; Protective Agents; Resveratrol; Stilbenes; X-Ray Diffraction | 2015 |
Potentiation of resveratrol-induced apoptosis by matrine in human hepatoma HepG2 cells.
Topics: Alkaloids; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cell Proliferation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Matrines; Proto-Oncogene Proteins c-bcl-2; Quinolizines; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
The effect of resveratrol on intimal hyperplasia and endothelial proliferation of rabbit carotid artery anastomosis.
Topics: Anastomosis, Surgical; Animals; Carotid Arteries; Carotid Intima-Media Thickness; Cell Proliferation; Endothelial Cells; Hyperplasia; Male; Models, Animal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Rabbits; Resveratrol; Stilbenes; Time Factors | 2015 |
Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach.
Topics: Cytokines; HT29 Cells; Humans; In Vitro Techniques; Janus Kinases; Mesalamine; Resveratrol; STAT Transcription Factors; Stilbenes | 2014 |
The beneficial effects of combined grape pomace and omija fruit extracts on hyperglycemia, adiposity and hepatic steatosis in db/db mice: a comparison with major index compounds.
Topics: Adiponectin; Adiposity; Animals; Biomarkers; Blood Glucose; Cyclooctanes; Diabetes Mellitus, Experimental; Fatty Liver; Fruit; Glycated Hemoglobin; Hyperglycemia; Insulin; Leptin; Lignans; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Plant Extracts; Polycyclic Compounds; Resistin; Resveratrol; Schisandra; Stilbenes; Vitis | 2014 |
Resveratrol augments paclitaxel treatment in MDA-MB-231 and paclitaxel-resistant MDA-MB-231 breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; Cytochrome P-450 CYP2C8; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Paclitaxel; Resveratrol; Stilbenes; Survivin; Tumor Stem Cell Assay | 2014 |
Resveratrol enhances mitomycin C-mediated suppression of human colorectal cancer cell proliferation by up-regulation of p21WAF1/CIP1.
Topics: alpha Karyopherins; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mad2 Proteins; Mitomycin; Nuclear Proteins; Resveratrol; Stilbenes; Trans-Activators; Transcription Factors; Up-Regulation | 2014 |
Synergistic combinations of tanshinone IIA and trans-resveratrol toward cisplatin-comparable cytotoxicity in HepG2 human hepatocellular carcinoma cells.
Topics: Abietanes; Apoptosis; Cell Cycle Checkpoints; Cell Survival; Cisplatin; DNA Fragmentation; Drug Synergism; Hep G2 Cells; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes | 2014 |
New water-soluble carbamate ester derivatives of resveratrol.
Topics: Animals; Carbamates; Esters; Intestinal Mucosa; Male; Molecular Structure; Permeability; Prodrugs; Rats; Resveratrol; Solubility; Stilbenes; Water | 2014 |
Identification of membrane proteins associated with phenylpropanoid tolerance and transport in Escherichia coli BL21.
Topics: Anti-Ulcer Agents; Biological Transport, Active; Drug Resistance, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Flavanones; Membrane Proteins; Phenylpropionates; Proteomics; Resveratrol; Rutin; Stilbenes | 2015 |
Green synthesis of bacterial gold nanoparticles conjugated to resveratrol as delivery vehicles.
Topics: Bacteria; Cell Line, Tumor; Cell Proliferation; Delftia; Gold; Humans; Metal Nanoparticles; Resveratrol; Stilbenes | 2014 |
Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
Topics: Adenomatous Polyposis Coli Protein; Animals; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Knockout; Mutation; Proto-Oncogene Proteins p21(ras); Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured | 2014 |
Silk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Cell Line; Colon; Cytokines; Delayed-Action Preparations; Disease Models, Animal; Inflammatory Bowel Diseases; Nanoparticles; Particle Size; Rats; Resveratrol; Silk; Stilbenes | 2014 |
Role of resveratrol in regulation of membrane transporters and integrity of human erythrocytes.
Topics: Erythrocytes; Humans; Membrane Transport Proteins; Oxidative Stress; Resveratrol; Stilbenes | 2014 |
[SIRT1 promote GTM cell DSBs repair and resist cellular senescence].
Topics: Cells, Cultured; Cellular Senescence; DNA Breaks, Double-Stranded; DNA Repair; Glaucoma; Humans; Hydrogen Peroxide; Oxidative Stress; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Trabecular Meshwork | 2014 |
Induction of secondary metabolite production by UV-C radiation in Vitis vinifera L. Öküzgözü callus cultures.
Topics: Catechin; Chromatography; Coumaric Acids; Crops, Agricultural; Flavonoids; Flavonols; Phenols; Plant Leaves; Plant Somatic Embryogenesis Techniques; Resveratrol; Secondary Metabolism; Stilbenes; Tocopherols; Ultraviolet Rays; Vitis | 2014 |
The effects of cadmium chloride on secondary metabolite production in Vitis vinifera cv. cell suspension cultures.
Topics: Cadmium Chloride; Cell Proliferation; Flavonoids; Flavonols; Phenols; Plant Leaves; Plant Somatic Embryogenesis Techniques; Primary Cell Culture; Resveratrol; Secondary Metabolism; Stilbenes; Tocopherols; Vitis | 2014 |
Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.
Topics: 3T3 Cells; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Fibroblast Growth Factor 2; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Proteins; Resveratrol; Stilbenes | 2014 |
The suppressive effect of resveratrol on HIF-1α and VEGF expression after warm ischemia and reperfusion in rat liver.
Topics: Animals; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; RNA, Messenger; Stilbenes; Vascular Endothelial Growth Factor A; Warm Ischemia | 2014 |
Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Proliferation; Curcumin; Drug Synergism; Fluorescent Antibody Technique; Head and Neck Neoplasms; Humans; In Vitro Techniques; Mice; Mice, Inbred BALB C; Phosphorylation; Reactive Oxygen Species; Resveratrol; Salivary Gland Neoplasms; Signal Transduction; Stilbenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.
Topics: Animals; Cells, Cultured; Curcumin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Insulin; Insulin-Secreting Cells; Mice; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Resveratrol; Stilbenes | 2014 |
Resveratrol inhibits hypoxia-inducible factor-1α-mediated androgen receptor signaling and represses tumor progression in castration-resistant prostate cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; beta Catenin; Cell Line, Tumor; Cell Nucleus; Diet; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice, Inbred BALB C; Mice, Nude; Phytotherapy; Plant Extracts; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Transcriptional Activation; Vitis | 2014 |
Effect of resveratrol on visceral white adipose tissue inflammation and insulin sensitivity in a mouse model of sleep apnea.
Topics: Animals; Anti-Obesity Agents; Diet, High-Fat; Disease Models, Animal; Eating; Inflammation; Insulin Resistance; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Obesity; Resveratrol; Sleep Apnea Syndromes; Stilbenes; Tumor Necrosis Factor-alpha; Weight Gain | 2015 |
Plasma metabolite profiles following trauma-hemorrhage: effect of posttreatment with resveratrol.
Topics: Animals; Carnitine; Drug Evaluation, Preclinical; Male; Metabolome; Metabolomics; Rats, Sprague-Dawley; Resveratrol; Shock, Hemorrhagic; Stilbenes; Vasodilator Agents; Wounds and Injuries | 2015 |
Protective effects of resveratrol on hepatotoxicity induced by isoniazid and rifampicin via SIRT1 modulation.
Topics: Alanine Transaminase; Animals; Antitubercular Agents; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Glutathione; Interleukin-10; Isoniazid; Liver; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Oxidation-Reduction; Oxidative Stress; Peroxidase; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Resveratrol; Rifampin; Sirtuin 1; Stilbenes; Transcription Factors; Tumor Necrosis Factor-alpha | 2014 |
Effect of resveratrol supplementation during culture on the quality and cryotolerance of bovine in vitro produced embryos.
Topics: Animals; Blastocyst; Cattle; Cell Survival; Cells, Cultured; Cryopreservation; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryonic Development; Fertilization in Vitro; Resveratrol; Stilbenes; Time Factors; Vitrification | 2014 |
In vitro assessment of biopolymer-modified porous silicon microparticles for wound healing applications.
Topics: Anti-Bacterial Agents; Biopolymers; Cell Line; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Fibroblasts; Humans; Microscopy, Electron, Scanning; Particle Size; Porosity; Reactive Oxygen Species; Resveratrol; Silicon; Spectroscopy, Fourier Transform Infrared; Stilbenes; Vancomycin; Wound Healing | 2014 |
Resveratrol entrapped niosomes as yoghurt additive.
Topics: Chemistry, Pharmaceutical; Functional Food; Liposomes; Resveratrol; Stilbenes; Yogurt | 2015 |
Cancer-specific interruption of glucose metabolism by resveratrol is mediated through inhibition of Akt/GLUT1 axis in ovarian cancer cells.
Topics: Apoptosis; Cell Line; Cell Line, Tumor; Cell Membrane; Epithelial Cells; Female; Glucose; Glucose Transporter Type 1; Humans; Ovarian Neoplasms; Protein Transport; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Photo-induced chemical reaction of trans-resveratrol.
Topics: Chromatography, High Pressure Liquid; Food Analysis; Furans; Isomerism; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Photochemical Processes; Photosensitizing Agents; Resveratrol; Singlet Oxygen; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes; Ultraviolet Rays | 2015 |
Enantioselective intramolecular C-H insertion reactions of donor-donor metal carbenoids.
Topics: Catalysis; Furans; Organometallic Compounds; Resveratrol; Rhodium; Stereoisomerism; Stilbenes | 2014 |
Diadenosine triphosphate is a novel factor which in combination with cyclodextrins synergistically enhances the biosynthesis of trans-resveratrol in Vitis vinifera cv. Monastrell suspension cultured cells.
Topics: Cells, Cultured; Cyclodextrins; Dinucleoside Phosphates; Drug Synergism; Gene Expression Regulation, Plant; Resveratrol; Stilbenes; Vitis | 2014 |
Phosphoproteomics reveals resveratrol-dependent inhibition of Akt/mTORC1/S6K1 signaling.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Chromatography, Liquid; Culture Media, Serum-Free; Humans; Immunoblotting; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Proto-Oncogene Proteins c-akt; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Tandem Mass Spectrometry; TOR Serine-Threonine Kinases | 2014 |
Dissecting the transcriptional response to elicitors in Vitis vinifera cells.
Topics: Acetates; Cyclodextrins; Cyclopentanes; Gene Expression Profiling; Gene Expression Regulation, Plant; Oxylipins; Plant Growth Regulators; Plant Proteins; Resveratrol; Stilbenes; Transcriptome; Up-Regulation; Vitis | 2014 |
Resveratrol increases nitric oxide production in the rat thick ascending limb via Ca2+/calmodulin.
Topics: AMP-Activated Protein Kinases; Animals; Calcium; Calmodulin; Gene Expression; Loop of Henle; Nitric Oxide; Protein Kinase Inhibitors; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Sulfonamides | 2014 |
Oligostilbenoids with acetylcholinesterase inhibitory activity from Dipterocarpus alatus.
Topics: Cholinesterase Inhibitors; Dipterocarpaceae; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Stilbenes | 2014 |
Effect of dietary supplementation with resveratrol on nutrient digestibility, methanogenesis and ruminal microbial flora in sheep.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Dietary Supplements; Digestion; Female; Methane; Resveratrol; Rumen; Sheep; Stilbenes | 2015 |
Production of anti-cancer agent using microbial biotransformation.
Topics: Antineoplastic Agents; Biotransformation; Fermentation; Gas Chromatography-Mass Spectrometry; HeLa Cells; Humans; Hydroxylation; Neoplasms; Resveratrol; Stilbenes; Streptomyces | 2014 |
Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species.
Topics: Antioxidants; Cells, Cultured; Endothelium, Vascular; Glucuronides; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidation-Reduction; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfates | 2014 |
Resveratrol based oral nutritional supplement produces long-term beneficial effects on structure and visual function in human patients.
Topics: Aged; Aged, 80 and over; Aging; Dietary Supplements; Female; Humans; Macular Degeneration; Male; Middle Aged; Nutritional Support; Resveratrol; Retina; Stilbenes; Time Factors; Treatment Outcome; Visual Acuity | 2014 |
[Protection of hypothermic preserved isolated rat hearts by resveratrol and its underlying mechanism].
Topics: Animals; Cryopreservation; Heart; Male; Organ Preservation; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Resveratrol attenuates the blood-brain barrier dysfunction by regulation of the MMP-9/TIMP-1 balance after cerebral ischemia reperfusion in rats.
Topics: Animals; Blood-Brain Barrier; Infarction, Middle Cerebral Artery; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tissue Inhibitor of Metalloproteinase-1 | 2015 |
In vitro and in vivo performance of supersaturable self-nanoemulsifying system of trans-resveratrol.
Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Drug Carriers; Emulsions; Hypromellose Derivatives; Intestinal Absorption; Male; Nanostructures; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Triglycerides; Water | 2016 |
Resveratrol inhibits the proliferation of human melanoma cells by inducing G1/S cell cycle arrest and apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; G1 Phase Cell Cycle Checkpoints; Humans; Melanoma; Resveratrol; Stilbenes | 2015 |
The combination of rapamycin and resveratrol blocks autophagy and induces apoptosis in breast cancer cells.
Topics: Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Estrogen Receptor alpha; Female; Humans; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Up-Regulation | 2015 |
Effects of yerba maté, a plant extract formulation ("YGD") and resveratrol in 3T3-L1 adipogenesis.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Antioxidants; Biomarkers, Tumor; Blotting, Western; Cell Differentiation; Cell Proliferation; Drug Combinations; Gene Expression Profiling; Gene Expression Regulation; Ilex paraguariensis; Mice; Obesity; Oligonucleotide Array Sequence Analysis; Plant Extracts; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2014 |
Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Bronchi; Cell Line; Cytotoxins; Epithelial Cells; Glutathione; Homeostasis; Humans; Lipid Peroxidation; Mutagens; Oxidative Stress; Oxides; Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol suppresses the inducible expression of CYP3A4 through the pregnane X receptor.
Topics: Animals; Cells, Cultured; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression; Hepatocytes; Male; Membrane Proteins; Mice, Inbred BALB C; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Steroid; Resveratrol; Rifampin; Stilbenes; Transcriptional Activation | 2014 |
Resveratrol as an inhibitor of pregnane X receptor (PXR): another lesson in PXR antagonism.
Topics: Antineoplastic Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Drug Discovery; Gene Expression; Humans; Molecular Targeted Therapy; Pregnane X Receptor; Receptors, Steroid; Resveratrol; Rifampin; Signal Transduction; Stilbenes | 2014 |
A dietary pattern rich in lignans, quercetin and resveratrol decreases the risk of oesophageal cancer.
Topics: Adenocarcinoma; Aged; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Case-Control Studies; Diet; Esophageal Neoplasms; Esophagus; Feeding Behavior; Female; Humans; Lignans; Logistic Models; Male; Middle Aged; Odds Ratio; Plant Extracts; Quercetin; Resveratrol; Stilbenes | 2014 |
Trans-resveratrol attenuates high fatty acid-induced P2X7 receptor expression and IL-6 release in PC12 cells: possible role of P38 MAPK pathway.
Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Interleukin-6; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptors, Purinergic P2X7; Resveratrol; Stilbenes | 2015 |
Protective effects of resveratrol oligomers from Vitis amurensis against sodium nitroprusside-induced neurotoxicity in human neuroblastoma SH-SY5Y cells.
Topics: Antioxidants; Benzofurans; Cell Line; DNA Fragmentation; Free Radical Scavengers; Humans; Hydroxyl Radical; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nitroprusside; Phenols; Plant Roots; Reactive Nitrogen Species; Resveratrol; Stilbenes; Vitis | 2015 |
GRIM‑19‑mediated Stat3 activation is a determinant for resveratrol‑induced proliferation and cytotoxicity in cervical tumor‑derived cell lines.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Proliferation; Cell Survival; Cyclin B1; Down-Regulation; Female; HeLa Cells; Humans; NADH, NADPH Oxidoreductases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2015 |
Resveratrol attenuates intermittent hypoxia-induced insulin resistance in rats: involvement of Sirtuin 1 and the phosphatidylinositol-4,5-bisphosphate 3-kinase/AKT pathway.
Topics: Animals; Blood Glucose; Body Weight; Gene Expression Regulation; Glucose Transporter Type 2; Hypoxia; Insulin; Insulin Resistance; Liver; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Exosome Multienzyme Ribonuclease Complex; Gene Expression; Humans; Inflammation Mediators; Mice; Mice, Knockout; Mutation; p38 Mitogen-Activated Protein Kinases; Resveratrol; RNA Stability; RNA-Binding Proteins; RNA, Messenger; Stilbenes; Trans-Activators | 2014 |
Piceatannol and its metabolite, isorhapontigenin, induce SIRT1 expression in THP-1 human monocytic cell line.
Topics: Cell Line; Humans; Monocytes; Passiflora; Plant Extracts; Resveratrol; RNA, Messenger; Seeds; Sirtuin 1; Stilbenes; Up-Regulation | 2014 |
Concentration-dependent biphasic effects of resveratrol on human natural killer cells in vitro.
Topics: Apoptosis; Humans; Jurkat Cells; Killer Cells, Natural; Resveratrol; Signal Transduction; Stilbenes | 2014 |
The sustained delivery of resveratrol or a defined grape powder inhibits new blood vessel formation in a mouse model of choroidal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Bruch Membrane; Cell Adhesion Molecules; Choroidal Neovascularization; Delayed-Action Preparations; Disease Models, Animal; Endothelial Cells; Female; Lasers; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Neovascularization, Pathologic; Powders; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Vitis | 2014 |
Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
Topics: Aged; Aged, 80 and over; alpha-Synuclein; Animals; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Female; Gene Expression Regulation; Glioma; Humans; Macrolides; Male; Mice; Mice, Transgenic; Middle Aged; Neurons; Parkinson Disease; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Resveratrol; RNA Polymerase II; Stilbenes; Substantia Nigra; TATA-Box Binding Protein; Transcription Factors | 2015 |
Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities.
Topics: Antioxidants; Apoptosis; Catechin; Cell Line, Tumor; Cell Proliferation; Drug Stability; Flavonoids; Flavonols; Gold; Green Chemistry Technology; Humans; Metal Nanoparticles; Polyphenols; Resveratrol; Stilbenes | 2014 |
Role of resveratrol on the cytotoxic effects and DNA damages of iododeoxyuridine and megavoltage radiation in spheroid culture of U87MG glioblastoma cell line.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Glioblastoma; Humans; Idoxuridine; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles; Trypan Blue; X-Rays | 2015 |
Anti-inflammatory properties of resveratrol in the retinas of type 2 diabetic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Diabetes Mellitus, Type 2; Inflammation Mediators; Insulin; Male; Rats; Rats, Wistar; Resveratrol; Retina; Stilbenes | 2015 |
A potential novel treatment strategy: inhibition of angiogenesis and inflammation by resveratrol for regression of endometriosis in an experimental rat model.
Topics: Angiogenesis Inhibitors; Animals; Ascitic Fluid; Disease Models, Animal; Endometriosis; Endometrium; Female; Inflammation; Leuprolide; Neovascularization, Pathologic; Rats; Rats, Wistar; Resveratrol; Stilbenes; Therapeutics | 2015 |
Protective effects of resveratrol on postmenopausal osteoporosis: regulation of SIRT1-NF-κB signaling pathway.
Topics: Animals; Base Sequence; Bone Density; Cell Differentiation; DNA Primers; Female; Humans; Middle Aged; NF-kappa B; Osteoblasts; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; X-Ray Microtomography | 2014 |
Modulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activity.
Topics: Analysis of Variance; Animals; Antigens, Polyomavirus Transforming; Antineoplastic Agents, Phytogenic; Biocatalysis; Cell Transformation, Neoplastic; Diet, High-Fat; Heterozygote; Male; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice, Transgenic; Point Mutation; Resveratrol; Sirtuin 1; Stilbenes; Tumor Burden | 2014 |
Resveratrol abrogates the effects of hypoxia on cell proliferation, invasion and EMT in osteosarcoma cells through downregulation of the HIF-1α protein.
Topics: Antineoplastic Agents, Phytogenic; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Osteosarcoma; Resveratrol; Stilbenes | 2015 |
Development and validation of a liquid chromatography with mass spectrometry method to determine resveratrol and piceid isomers in beeswax.
Topics: Chromatography, Liquid; Glucosides; Isomerism; Limit of Detection; Mass Spectrometry; Reference Standards; Reproducibility of Results; Resveratrol; Stilbenes; Waxes | 2015 |
Resveratrol exerts an anti-apoptotic effect on human bronchial epithelial cells undergoing cigarette smoke exposure.
Topics: Apoptosis; Cell Line; Epithelial Cells; Gene Knockout Techniques; HSP70 Heat-Shock Proteins; Humans; Protective Agents; Respiratory Mucosa; Resveratrol; RNA Interference; RNA, Small Interfering; Sirtuin 1; Smoke; Smoking; Stilbenes | 2015 |
Resveratrol and genistein inhibition of rat isolated gastrointestinal contractions and related mechanisms.
Topics: Animals; Calcium Channels, L-Type; Cyclic AMP; Dose-Response Relationship, Drug; Duodenum; Female; Gastric Mucosa; Gastrointestinal Motility; Genistein; In Vitro Techniques; KATP Channels; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Phytoestrogens; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Resveratrol; Signal Transduction; Stilbenes; Stomach | 2014 |
Effects of long-term feeding of the polyphenols resveratrol and kaempferol in obese mice.
Topics: Alanine Transaminase; Animals; Blood Glucose; Body Weight; Cholesterol; Gene Expression Regulation; Insulin; Kaempferols; Liver; Male; Mice, Inbred C57BL; Obesity; Resveratrol; Rotarod Performance Test; Stilbenes; Survival Rate; Triglycerides | 2014 |
[Resveratrol attenuates hypoxia-reperfusion injury induced rat myocardium microvascular endothelial cell dysfunction through upregulating PI3K/Akt/SVV pathways].
Topics: Animals; Apoptosis; Cell Proliferation; Chromones; Endothelial Cells; Enzyme Inhibitors; Heart; Hypoxia; Morpholines; Myocardium; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes; Up-Regulation | 2014 |
mPEG-b-PCL/TPGS mixed micelles for delivery of resveratrol in overcoming resistant breast cancer.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Tolerance; Humans; Micelles; Polyesters; Polyethylene Glycols; Resveratrol; Stilbenes; Vitamin E | 2015 |
Vitamin E loaded resveratrol nanoemulsion for brain targeting for the treatment of Parkinson's disease by reducing oxidative stress.
Topics: Animals; Antioxidants; Biological Availability; Brain; Chemistry, Pharmaceutical; Emulsions; Female; Male; Nanoparticles; Oxidative Stress; Parkinson Disease; Particle Size; Polysorbates; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Swine; Viscosity; Vitamin E | 2014 |
Resveratrol improves high-fructose-induced vascular dysfunction in rats.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Fructose; Fructose-Bisphosphate Aldolase; Glucose Transporter Type 5; Insulin; Leptin; Male; Muscle, Smooth, Vascular; Rats, Wistar; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Vasoconstriction; Vasodilation | 2014 |
Resveratrol treatment of mice with pressure-overload-induced heart failure improves diastolic function and cardiac energy metabolism.
Topics: Animals; Disease Models, Animal; Energy Metabolism; Heart Failure, Diastolic; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; Resveratrol; Ribonucleotide Reductases; Stilbenes; Stroke Volume; Vasodilator Agents; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Resveratrol prevents pathological but not physiological cardiac hypertrophy.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cells, Cultured; Exercise; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Insulin-Like Growth Factor I; Mice, Inbred C57BL; Myocytes, Cardiac; NFATC Transcription Factors; Rats; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; Transcriptional Activation; Ventricular Function | 2015 |
Non-toxic plant metabolites regulate Staphylococcus viability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections.
Topics: Anti-Bacterial Agents; Biofilms; Genistein; Hydroxybenzoates; Microbial Sensitivity Tests; Plant Extracts; Resveratrol; Skin Diseases, Bacterial; Staphylococcal Infections; Staphylococcus; Stilbenes; Vaccinium macrocarpon | 2014 |
Resveratrol suppresses TPA-induced matrix metalloproteinase-9 expression through the inhibition of MAPK pathways in oral cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Down-Regulation; Enzyme Activation; Head and Neck Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Resveratrol; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Stilbenes; Tetradecanoylphorbol Acetate; Tongue Neoplasms | 2015 |
Resveratrol attenuates inflammation in the rat heart subjected to ischemia-reperfusion: Role of the TLR4/NF-κB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Down-Regulation; Heart; Inflammation; Male; Myocardial Reperfusion Injury; Myocardium; Neutrophils; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Solving the supply of resveratrol tetramers from Papua New Guinean rainforest anisoptera species that inhibit bacterial type III secretion systems.
Topics: Animals; Anti-Bacterial Agents; Benzofurans; Dipterocarpaceae; Heterocyclic Compounds, 4 or More Rings; Inhibitory Concentration 50; Microbial Sensitivity Tests; Odonata; Papua New Guinea; Phenols; Rainforest; Resveratrol; Stilbenes; Yersinia pseudotuberculosis | 2014 |
Resveratrol attenuates intermittent hypoxia-induced macrophage migration to visceral white adipose tissue and insulin resistance in male mice.
Topics: Animals; Anti-Obesity Agents; Drug Evaluation, Preclinical; Eating; Hypoxia; Insulin; Insulin Resistance; Intra-Abdominal Fat; Leptin; Macrophages; Male; Mice, Inbred C57BL; Random Allocation; Resveratrol; Stilbenes; Weight Gain | 2015 |
Design and synthesis of resveratrol-salicylate hybrid derivatives as CYP1A1 inhibitors.
Topics: Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Humans; Models, Molecular; Molecular Structure; Resveratrol; RNA, Messenger; Salicylates; Stilbenes; Structure-Activity Relationship | 2015 |
Knockdown of Bcl-xL enhances growth-inhibiting and apoptosis-inducing effects of resveratrol and clofarabine in malignant mesothelioma H-2452 cells.
Topics: Adenine Nucleotides; Antimetabolites, Antineoplastic; Apoptosis; Arabinonucleosides; bcl-X Protein; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Proliferation; Clofarabine; G2 Phase Cell Cycle Checkpoints; Gene Knockdown Techniques; Humans; Leupeptins; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Mesothelioma; Mesothelioma, Malignant; Myeloid Cell Leukemia Sequence 1 Protein; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Stilbenes | 2014 |
Regulation of resveratrol production in Vitis amurensis cell cultures by calcium-dependent protein kinases.
Topics: Biomass; Cells, Cultured; Genes, Plant; Phylogeny; Plants, Genetically Modified; Protein Kinases; Resveratrol; Stilbenes; Transformation, Genetic; Transgenes; Vitis | 2015 |
The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Colon; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Histones; Humans; Polyploidy; Protein Kinases; Rats; Reactive Oxygen Species; Resveratrol; S Phase; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2014 |
[Resveratrol enhances radiosensitivity of human hypopharyngeal carcinoma cell line in nude mice].
Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Mice; Mice, Nude; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes; Transplantation, Heterologous; Tumor Burden | 2014 |
Novel antifungal mechanism of resveratrol: apoptosis inducer in Candida albicans.
Topics: Antifungal Agents; Apoptosis; Candida albicans; Caspases; Free Radicals; Mitochondria; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Anti-inflammatory activities of Gouania leptostachya methanol extract and its constituent resveratrol.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cyclooxygenase 2; Dinoprostone; Gastritis; I-kappa B Proteins; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Proto-Oncogene Proteins c-akt; Resveratrol; Rhamnaceae; Stilbenes; Thailand | 2015 |
Cross effects of resveratrol and mesenchymal stem cells on liver regeneration and homing in partially hepatectomized rats.
Topics: Animals; Bone Marrow Cells; Gene Expression; Hepatectomy; Interleukin-6; Liver Regeneration; Mesenchymal Stem Cell Transplantation; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Possible role of resveratrol targeting estradiol and neprilysin pathways in lipopolysaccharide model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Estradiol; Lipopolysaccharides; Memory; Mice; Motor Activity; Neprilysin; Random Allocation; Resveratrol; Signal Transduction; Stilbenes; Treatment Outcome | 2015 |
Resveratrol effectively attenuates α-naphthyl-isothiocyanate-induced acute cholestasis and liver injury through choleretic and anti-inflammatory mechanisms.
Topics: 1-Naphthylisothiocyanate; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Bile; Biomarkers; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Cytoprotection; Disease Models, Animal; DNA, Mitochondrial; Inflammation Mediators; Liver; Male; Membrane Transport Proteins; Neutrophil Infiltration; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Resveratrol ameliorates high glucose and high-fat/sucrose diet-induced vascular hyperpermeability involving Cav-1/eNOS regulation.
Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Capillary Permeability; Cattle; Caveolin 1; Cells, Cultured; Diet, High-Fat; Dietary Carbohydrates; Dietary Fats; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Glucose; Male; Nitric Oxide Synthase Type III; Phosphorylation; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Sucrose | 2014 |
Salicylic acid induces alterations in the methylation pattern of the VaSTS1, VaSTS2, and VaSTS10 genes in Vitis amurensis Rupr. cell cultures.
Topics: Acyltransferases; Cells, Cultured; DNA Methylation; Gene Expression Regulation, Plant; Plant Proteins; Resveratrol; Salicylic Acid; Sequence Analysis, DNA; Stilbenes; Vitis | 2015 |
Resveratrol ameliorates cardiac dysfunction induced by pressure overload in rats via structural protection and modulation of Ca(2+) cycling proteins.
Topics: Animals; Calcium; Heart; Male; Pressure; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Resveratrol synergistically triggers apoptotic cell death with arsenic trioxide via oxidative stress in human lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Humans; Lung Neoplasms; Oxidative Stress; Oxides; Resveratrol; Stilbenes | 2015 |
Firefly luciferase inhibition: a widely neglected problem.
Topics: Enzyme Inhibitors; Genes, Reporter; Inhibitory Concentration 50; Luciferases, Firefly; Research Design; Resveratrol; Stilbenes | 2015 |
Protective effect of resveratrol against cisplatin-induced ototoxicity in HEI-OC1 auditory cells.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line; Cell Survival; Cisplatin; Hair Cells, Auditory; Mice, Transgenic; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol enhances palmitate-induced ER stress and apoptosis in cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; DNA-Binding Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Hep G2 Cells; Humans; Neoplasms; Palmitates; Reactive Oxygen Species; Regulatory Factor X Transcription Factors; Resveratrol; Stearoyl-CoA Desaturase; Stilbenes; Transcription Factor CHOP; Transcription Factors; Triglycerides; X-Box Binding Protein 1 | 2014 |
Anti-proliferative and gene expression actions of resveratrol in breast cancer cells in vitro.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Humans; Integrin alphaVbeta3; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Purification and functional characterization of the first stilbene glucoside-specific β-glucosidase isolated from Lactobacillus kimchi.
Topics: Bacterial Proteins; beta-Glucosidase; Biotransformation; Disaccharides; Glucosides; Industrial Microbiology; Lactobacillus; Resveratrol; Stilbenes; Substrate Specificity | 2014 |
Relaxant and antioxidant capacity of the red wine polyphenols, resveratrol and quercetin, on isolated mice corpora cavernosa.
Topics: Acetylcholine; Animals; Antioxidants; Guanylate Cyclase; Male; Mice; Nitric Oxide; Nitroprusside; Oxidative Stress; Penile Erection; Penis; Polyphenols; Quercetin; Receptors, Cytoplasmic and Nuclear; Resveratrol; Soluble Guanylyl Cyclase; Stilbenes; Vasodilator Agents; Wine | 2015 |
Multi-drug resistance protein (Mrp) 3 may be involved in resveratrol protection against methotrexate-induced testicular damage.
Topics: Animals; Antimetabolites, Antineoplastic; Antioxidants; Body Weight; Cell Line, Tumor; Drug Resistance, Multiple; Humans; Male; Methotrexate; Multidrug Resistance-Associated Proteins; Prostatic Neoplasms; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Testis; Testosterone | 2014 |
Resveratrol-loaded polymeric nanoparticles suppress glucose metabolism and tumor growth in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Drug Liberation; Glucose; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Burden | 2015 |
Resveratrol prevents akinesia and restores neuronal tyrosine hydroxylase immunoreactivity in the substantia nigra pars compacta of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Dyskinesias; Male; Motor Activity; Neuroglia; Neurons; Neuroprotective Agents; Pars Compacta; Random Allocation; Rats, Wistar; Resveratrol; Stilbenes; Tyrosine 3-Monooxygenase | 2014 |
A successful experimental model for intimal hyperplasia prevention using a resveratrol-delivering balloon.
Topics: Angioplasty, Balloon; Animals; Cardiovascular Agents; Cell Proliferation; Cells, Cultured; Coated Materials, Biocompatible; Disease Models, Animal; Equipment Design; Humans; Hyperplasia; Iliac Artery; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Rabbits; Resveratrol; Stilbenes; Vascular Access Devices; Vascular System Injuries | 2016 |
Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer.
Topics: Acetylation; Animals; Cell Line, Tumor; Cell Nucleus; Down-Regulation; Enzyme Activation; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Immunoprecipitation; Male; Mi-2 Nucleosome Remodeling and Deacetylase Complex; Mice, Nude; Models, Biological; Nucleosomes; Prostatic Neoplasms; Protein Binding; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Repressor Proteins; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators; Up-Regulation; Xenograft Model Antitumor Assays | 2015 |
Resveratrol suppresses the proliferation of breast cancer cells by inhibiting fatty acid synthase signaling pathway.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Receptor, ErbB-2; Resveratrol; Signal Transduction; Stilbenes | 2014 |
Estrogen receptor-mediated resveratrol actions on blood-brain barrier of ovariectomized mice.
Topics: Animals; Blood-Brain Barrier; Brain; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Female; Hypoxia-Inducible Factor 1, alpha Subunit; Infarction, Middle Cerebral Artery; Mice, Inbred C57BL; Neuroprotective Agents; Ovariectomy; Postmenopause; Receptors, Estrogen; Resveratrol; Stilbenes; Tight Junction Proteins; Vascular Endothelial Growth Factor A | 2015 |
The effect of resveratrol on the recurrent attacks of gouty arthritis.
Topics: Animals; Arthritis, Gouty; Disease Models, Animal; Female; Kidney; Male; Mice; Mice, Inbred C57BL; Recurrence; Resveratrol; Stilbenes; Treatment Outcome; Uric Acid | 2016 |
Skin resistance to oxidative stress induced by resveratrol: from Nrf2 activation to GSH biosynthesis.
Topics: Antioxidants; Blotting, Western; Cells, Cultured; Chromatography, Liquid; Glutathione; Humans; Keratinocytes; NF-E2-Related Factor 2; Oxidative Stress; Protein Transport; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Absorption; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes | 2015 |
Resveratrol exerts anti-inflammatory and neuroprotective effects to prevent memory deficits in rats exposed to chronic unpredictable mild stress.
Topics: Amygdala; Animals; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Emotions; Hippocampus; Injections, Intraperitoneal; Interleukin-1beta; Male; Memory Disorders; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats, Wistar; Resveratrol; Spatial Learning; Spatial Memory; Stilbenes; Stress, Psychological; Tumor Necrosis Factor-alpha; Uncertainty | 2015 |
Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells.
Topics: Biomarkers; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Humans; Mesenchymal Stem Cells; Neurons; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Response of direct or priming defense against Botrytis cinerea to methyl jasmonate treatment at different concentrations in grape berries.
Topics: Acetates; Benzofurans; Botrytis; Cyclopentanes; Disease Resistance; Fruit; Gene Expression Regulation; Hydrogen Peroxide; Oxylipins; Plant Growth Regulators; Resveratrol; Stilbenes; Vitis | 2015 |
Metabolite profiling elucidates communalities and differences in the polyphenol biosynthetic pathways of red and white Muscat genotypes.
Topics: Anthocyanins; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Citric Acid; Cluster Analysis; Flavonols; Genotype; Malates; Mass Spectrometry; Metabolome; Metabolomics; Phylogeny; Polymorphism, Single Nucleotide; Polyphenols; Principal Component Analysis; Quercetin; Resveratrol; Species Specificity; Stilbenes; Vitis | 2015 |
Is resveratrol a potential substitute for leuprolide acetate in experimental endometriosis?
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Endometriosis; Endometrium; Female; Leuprolide; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome; Vascular Endothelial Growth Factor A | 2015 |
Transcriptomic analysis of grape (Vitis vinifera L.) leaves after exposure to ultraviolet C irradiation.
Topics: Cluster Analysis; DNA Probes; Down-Regulation; Flavonoids; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Plant Leaves; Plant Proteins; Reproducibility of Results; Resveratrol; RNA, Messenger; Stilbenes; Stress, Physiological; Time Factors; Transcription Factors; Transcriptome; Ultraviolet Rays; Up-Regulation; Vitis | 2014 |
Resveratrol dimers, nutritional components in grape wine, are selective ROS scavengers and weak Nrf2 activators.
Topics: Antioxidant Response Elements; Dimerization; Free Radical Scavengers; NF-E2-Related Factor 2; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Vitis; Wine | 2015 |
Resveratrol attenuates HMGB1 signaling and inflammation in house dust mite-induced atopic dermatitis in mice.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Female; HMGB1 Protein; Mice, Inbred Strains; Pyroglyphidae; Resveratrol; Severity of Illness Index; Signal Transduction; Skin; Stilbenes; Th1 Cells; Th2 Cells | 2014 |
Effects of resveratrol on ovarian response to controlled ovarian hyperstimulation in ob/ob mice.
Topics: Animals; Blood Glucose; Female; Mice; Mice, Inbred C57BL; Mice, Obese; Ovarian Hyperstimulation Syndrome; Ovary; Resveratrol; Stilbenes | 2015 |
Resveratrol modulates the topoisomerase inhibitory potential of doxorubicin in human colon carcinoma cells.
Topics: Cell Death; Cell Proliferation; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; Doxorubicin; HT29 Cells; Humans; Intracellular Space; Resveratrol; Rhodamines; Stilbenes; Topoisomerase Inhibitors | 2014 |
Resveratrol protects PC12 cells from high glucose-induced neurotoxicity via PI3K/Akt/FoxO3a pathway.
Topics: Acetylcysteine; Animals; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Nucleus; Chromones; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glucose; Membrane Proteins; Morpholines; Neuroprotection; Neuroprotective Agents; Neurotoxins; Oxidative Stress; PC12 Cells; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol enhances splicing of insulin receptor exon 11 in myotonic dystrophy type 1 fibroblasts.
Topics: Exons; Fibroblasts; HeLa Cells; Humans; Myotonic Dystrophy; Protein Splicing; Receptor, Insulin; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Up-Regulation | 2015 |
Inhibition of AMPK expression in skeletal muscle by systemic inflammation in COPD rats.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; Male; Muscle Weakness; Muscle, Skeletal; Pulmonary Disease, Chronic Obstructive; Rats, Wistar; Resveratrol; Ribonucleotides; RNA, Messenger; Sirtuin 1; Stilbenes; Time Factors; Tumor Necrosis Factor-alpha | 2014 |
Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells.
Topics: Acetylation; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Neurons; PC12 Cells; Peptide Fragments; Rats; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers.
Topics: Acetyl Coenzyme A; Anacardic Acids; Animals; Autophagy; Caloric Restriction; Catalysis; Catechin; Curcumin; Food Deprivation; Humans; Leucine; Mice; Models, Animal; Niacinamide; Plant Extracts; Resveratrol; Spermidine; Starvation; Stilbenes; Terpenes | 2014 |
Long-term oral resveratrol intake provides nutritional preconditioning against myocardial ischemia/reperfusion injury: involvement of VDAC1 downregulation.
Topics: Administration, Oral; Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Cytochromes c; Down-Regulation; Gene Expression Regulation; Heart; Ischemic Preconditioning, Myocardial; Mice; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Organ Culture Techniques; Resveratrol; Stilbenes; Voltage-Dependent Anion Channel 1 | 2015 |
Polydatin prevents angiotensin II-induced cardiac hypertrophy and myocardial superoxide generation.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Cells, Cultured; Glucosides; Male; Myocardium; Myocytes, Cardiac; NADPH Oxidases; Organ Size; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Superoxides; Ventricular Myosins | 2015 |
Nanoparticle-mediated dual delivery of an antioxidant and a peptide against the L-Type Ca2+ channel enables simultaneous reduction of cardiac ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Calcium Channels, L-Type; Curcumin; Drug Carriers; Drug Interactions; Male; Membrane Potential, Mitochondrial; Mice; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nanoparticles; Oxidative Stress; Peptide Fragments; Polyethyleneimine; Polymethacrylic Acids; Rats; Resveratrol; Stilbenes; Superoxides | 2015 |
Resveratrol attenuated homocysteine-induced apoptosis of rat ventricular myocytes.
Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Apoptosis; Disease Models, Animal; Heart Ventricles; Homocysteine; Myocytes, Cardiac; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2014 |
Resveratrol possesses protective effects in a pristane-induced lupus mouse model.
Topics: Animals; Antigens, CD; Antigens, CD19; Antigens, Differentiation, T-Lymphocyte; Apoptosis; B-Lymphocytes; CD4-Positive T-Lymphocytes; Gene Expression Regulation; Humans; Inflammation; Lectins, C-Type; Lupus Erythematosus, Systemic; Mice; Receptors, Transferrin; Resveratrol; Sirtuin 1; Stilbenes; Terpenes | 2014 |
Resveratrol inhibits trophoblast apoptosis through oxidative stress in preeclampsia-model rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Pressure; Cell Line; Disease Models, Animal; Female; Hypoxia; Oxidative Stress; Phenotype; Placenta; Pre-Eclampsia; Pregnancy; Rats; Resveratrol; Stilbenes; Trophoblasts | 2014 |
Evaluation of a special combination of glucan with organic selenium derivative in different murine tumor models.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Lewis Lung; Cell Line, Tumor; Cyclophosphamide; Disaccharides; Female; Glucans; Humans; Immunologic Factors; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organoselenium Compounds; Proteoglycans; Receptors, Transforming Growth Factor beta; Resveratrol; Stilbenes | 2014 |
Synthesis of a monofunctional platinum compound and its activity alone and in combination with phytochemicals in ovarian tumor models.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Cisplatin; Curcumin; Deoxyribonuclease BamHI; DNA; DNA Fragmentation; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Female; Genistein; Glutathione; Humans; Organoplatinum Compounds; Ovarian Neoplasms; Phytochemicals; Plasmids; Platinum Compounds; Resveratrol; Stilbenes | 2014 |
Quantitative nuclear proteomics identifies that miR-137-mediated EZH2 reduction regulates resveratrol-induced apoptosis of neuroblastoma cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Nucleus; Computational Biology; Enhancer of Zeste Homolog 2 Protein; Gene Knockdown Techniques; HEK293 Cells; Humans; Isotope Labeling; Mice; MicroRNAs; Neuroblastoma; Nuclear Proteins; Polycomb Repressive Complex 2; Protein Biosynthesis; Proteome; Proteomics; Reproducibility of Results; Resveratrol; RNA, Messenger; Stilbenes; Time Factors | 2015 |
Metabolism of skin-absorbed resveratrol into its glucuronized form in mouse skin.
Topics: Administration, Cutaneous; Animals; Biological Availability; Cells, Cultured; Female; Glucuronides; Humans; Inflammation; Male; Mice; Resveratrol; Skin; Skin Absorption; Stilbenes | 2014 |
Ovarian failure in diabetic rat model: nuclear factor-kappaB, oxidative stress, and pentraxin-3.
Topics: Animals; Antioxidants; C-Reactive Protein; Diabetes Mellitus, Experimental; Female; NF-kappa B; Ovarian Reserve; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Serum Amyloid P-Component; Stilbenes | 2014 |
Streptococcus pneumoniae-Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol.
Topics: Animals; Antioxidants; Autolysis; Bacterial Proteins; Cell Line; Cell Survival; Epithelial Cells; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Interleukin-8; Lung; Mice; NF-E2-Related Factor 2; Oxidative Stress; Pneumonia, Pneumococcal; Resveratrol; Stilbenes; Streptococcus pneumoniae; Streptolysins | 2015 |
Fruit-localized photoreceptors increase phenolic compounds in berry skins of field-grown Vitis vinifera L. cv. Malbec.
Topics: Anthocyanins; Argentina; Flavonoids; Flavonols; Fruit; Molecular Structure; Phenols; Photoperiod; Plant Leaves; Polyphenols; Resveratrol; Sensory Receptor Cells; Stilbenes; Vitis | 2015 |
Resveratrol induces cell cycle arrest via a p53-independent pathway in A549 cells.
Topics: Antineoplastic Agents; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Humans; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Effects of resveratrol supplementation on bone growth in young rats and microarchitecture and remodeling in ageing rats.
Topics: Adipogenesis; Aging; Alkaline Phosphatase; Animals; Bone Density; Bone Development; Bone Remodeling; Collagen Type I; Dietary Supplements; Male; Models, Animal; Osteocalcin; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes | 2014 |
Resveratrol regulates mitochondrial reactive oxygen species homeostasis through Sirt3 signaling pathway in human vascular endothelial cells.
Topics: Apoptosis; Cell Survival; Cells, Cultured; Homeostasis; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 3; Stilbenes | 2014 |
Effects of resveratrol on growth and skeletal muscle physiology of juvenile southern flounder.
Topics: Animal Feed; Animals; Dietary Supplements; Fish Proteins; Flounder; Lipid Peroxidation; Mitochondria, Muscle; Muscle, Skeletal; Protein Carbonylation; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Stilbenes; Ubiquitination | 2015 |
Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via the TGF-β/Smad3 pathway.
Topics: Animals; Cardiomegaly; Cells, Cultured; Collagen; Fibrosis; Heart; Male; Mice; Myocardium; Myocytes, Cardiac; Myofibroblasts; Resveratrol; Sirtuin 3; Smad3 Protein; Stilbenes; Transforming Growth Factor beta | 2015 |
Anti-inflammatory effects of a triple-bond resveratrol analog: structure and function relationship.
Topics: Acetylene; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cytokines; Lipopolysaccharides; Macrophages; Membrane Potential, Mitochondrial; Mice; NF-kappa B; Resorcinols; Resveratrol; Signal Transduction; Stilbenes; Structure-Activity Relationship | 2015 |
Resveratrol ameliorates experimental periodontitis in diabetic mice through negative regulation of TLR4 signaling.
Topics: Animal Experimentation; Animals; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred C57BL; Periodontitis; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4 | 2015 |
Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Amyloid; Arginine; Benzothiazoles; Catechin; DNA Mutational Analysis; Histidine; Humans; Islet Amyloid Polypeptide; Molecular Sequence Data; Mutant Proteins; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Structure-Activity Relationship; Thiazoles | 2015 |
Direct identification and characterization of phenolic compounds from crude extracts of buds and internodes of grapevine (Vitis vinifera cv Merlot).
Topics: Benzofurans; Chromatography, High Pressure Liquid; Flavonols; Mass Spectrometry; Phenols; Plant Extracts; Proanthocyanidins; Quercetin; Resveratrol; Stilbenes; Vitis | 2014 |
Resveratrol trimers from seed cake of Paeonia rockii.
Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Paeonia; Plant Extracts; Resveratrol; Seeds; Stilbenes | 2014 |
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol.
Topics: Alternative Splicing; Animals; Biocatalysis; Catalytic Domain; Cell Nucleus; Crystallography, X-Ray; Culture Media, Serum-Free; Enzyme Activation; Humans; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Poly (ADP-Ribose) Polymerase-1; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Protein Conformation; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Tyrosine-tRNA Ligase | 2015 |
Red wines and flavonoids diminish Staphylococcus aureus virulence with anti-biofilm and anti-hemolytic activities.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Erythrocytes; Flavonoids; Hemolysis; Humans; Quercetin; Resveratrol; Staphylococcus aureus; Stilbenes; Tannins; Virulence; Wine | 2015 |
Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphate; Animals; Apoptosis Regulatory Proteins; Autophagy; Calcium-Binding Proteins; Carrier Proteins; Caspase 1; Cells, Cultured; Gene Expression Regulation; Inflammation; Interleukin-1beta; Macrophages; Mice; Mitochondria; Mitogen-Activated Protein Kinase Kinases; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol potentiates vitamin D and nuclear receptor signaling.
Topics: Animals; Caco-2 Cells; Cell Line; HCT116 Cells; Humans; Mice; Protein Binding; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Resveratrol; Retinoid X Receptors; Signal Transduction; Stilbenes; Vitamin D Response Element | 2015 |
Prenylated flavonoids and resveratrol derivatives isolated from Artocarpus communis with the ability to overcome TRAIL resistance.
Topics: Apoptosis; Artocarpus; Flavonoids; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Reactive Oxygen Species; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53 | 2015 |
Resveratrol prevents high glucose-induced epithelial-mesenchymal transition in renal tubular epithelial cells by inhibiting NADPH oxidase/ROS/ERK pathway.
Topics: Antioxidants; Cell Line; Diabetic Nephropathies; Drug Evaluation, Preclinical; Epithelial Cells; Epithelial-Mesenchymal Transition; Glucose; Humans; Kidney; Kidney Tubules; MAP Kinase Signaling System; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Pifithrin-α ameliorates resveratrol-induced two-cell block in mouse preimplantation embryos in vitro.
Topics: Animals; Benzothiazoles; Blastocyst; Cytoprotection; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Mice; Resveratrol; Stilbenes; Toluene; Tumor Suppressor Protein p53 | 2015 |
Efficacy of antioxidants as a Complementary and Alternative Medicine (CAM) in combination with the chemotherapeutic agent doxorubicin.
Topics: 3T3 Cells; Animals; Antibiotics, Antineoplastic; Antioxidants; Antrodia; Breast Neoplasms; Complementary Therapies; Curcumin; Doxorubicin; Drug Synergism; Female; Glucosides; Humans; MCF-7 Cells; Mice; Plant Extracts; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid-DPPC microparticles as a wound healing system.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antioxidants; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Hyaluronic Acid; Oxidative Stress; Resveratrol; Stilbenes; Structure-Activity Relationship; Wound Healing | 2015 |
[Resveratrol improves intestinal injury in hemorrhagic shock rats by protection of mitochondria and reduction of oxidative stress].
Topics: Adenosine Triphosphate; Animals; Arterial Pressure; Catalase; Cytochromes c; Glutathione Peroxidase; Intestines; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Shock, Hemorrhagic; Specific Pathogen-Free Organisms; Stilbenes; Superoxide Dismutase | 2014 |
Overview of scientific evidence for chocolate health benefits.
Topics: Antioxidants; Cacao; Cardiovascular Diseases; Cognition; Flavonoids; Functional Food; Humans; Resveratrol; Stilbenes | 2015 |
[Resveratrol alleviates oxidative injury from high glucose-induced human lens epithelial cells and its possible mechanism].
Topics: Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Dehydroascorbic Acid; Epithelial Cells; Glucose; Humans; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2014 |
Differential contribution of ROS to resveratrol-induced cell death and loss of self-renewal capacity of ovarian cancer stem cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Ovarian Neoplasms; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol at anti-angiogenesis/anticancer concentrations suppresses protein kinase G signaling and decreases IAPs expression in HUVECs.
Topics: Angiogenesis Inhibitors; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Drug Screening Assays, Antitumor; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Inhibitor of Apoptosis Proteins; Isoenzymes; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Cardioprotective effect of resveratrol on atherogenic diet-fed rats.
Topics: Adenylate Kinase; Animals; Antioxidants; Aorta; Cardiovascular Diseases; Catalase; Diet, Atherogenic; Glutathione Peroxidase; Heart; Lipid Metabolism; Lipid Peroxidation; Lipids; Male; Myocardium; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2014 |
The proteomic and genomic teratogenicity elicited by valproic acid is preventable with resveratrol and α-tocopherol.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Carrier Proteins; Chick Embryo; Chromatography, Liquid; Filamins; Gene Expression Regulation; Membrane Proteins; Myosin Light Chains; Phosphatidylethanolamine Binding Protein; Proteome; Resveratrol; Serum Albumin; Stilbenes; Tandem Mass Spectrometry; Teratogens; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Valproic Acid | 2014 |
Effects of resveratrol on doxorubicin induced testicular damage in rats.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Disease Models, Animal; Doxorubicin; In Situ Nick-End Labeling; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Sperm Motility; Spermatozoa; Stilbenes; Testis | 2015 |
Resveratrol inhibits high glucose induced collagen upregulation in cardiac fibroblasts through regulating TGF-β1-Smad3 signaling pathway.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Collagen; Diabetes Mellitus, Experimental; Fibroblasts; Glucose; Mice; Mice, Inbred C57BL; Myocardium; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1; Up-Regulation | 2015 |
Resveratrol mimics insulin activity in the adipogenic commitment of human bone marrow mesenchymal stromal cells.
Topics: Adipogenesis; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Humans; Insulins; Mesenchymal Stem Cells; Phosphorylation; Resveratrol; Stilbenes | 2015 |
Blunted hypertrophic response in old mouse muscle is associated with a lower satellite cell density and is not alleviated by resveratrol.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Count; Cell Differentiation; Cell Proliferation; Hypertrophy; Male; Mice, Inbred C57BL; Muscle Proteins; Muscle, Skeletal; Resveratrol; Satellite Cells, Skeletal Muscle; Stilbenes | 2015 |
Rapid quantification of resveratrol in mouse plasma by ultra high pressure liquid chromatography (UPLC) coupled to tandem mass spectrometry.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Mice; Molecular Structure; Reference Standards; Resveratrol; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry | 2014 |
Anti-tumor properties of cis-resveratrol methylated analogs in metastatic mouse melanoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Inhibitory Concentration 50; Melanoma, Experimental; Mice; Neoplasm Metastasis; Resveratrol; Stilbenes | 2015 |
Resveratrol Attenuates Oxidative Stress and Extends Life Span in the Annual Fish Nothobranchius guentheri.
Topics: Aging; Animals; Antioxidants; Biomarkers; Fishes; Longevity; Mice; Models, Animal; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Sulfamethoxazole-trimethoprim associated with resveratrol for the treatment of toxoplasmosis in mice: Influence on the activity of enzymes involved in brain neurotransmission.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Brain; Drug Therapy, Combination; Enzyme Inhibitors; Liver; Mice; Parasite Load; Resveratrol; Stilbenes; Synaptic Transmission; Toxoplasma; Toxoplasmosis, Animal; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2015 |
IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Janus Kinase 1; Lipopolysaccharides; Mice; Microglia; Resveratrol; RNA, Messenger; STAT3 Transcription Factor; Stilbenes; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins | 2015 |
Cross-linked poly(acrylic acids) microgels and agarose as semi-interpenetrating networks for resveratrol release.
Topics: Acrylic Resins; Animals; Cell Line; Cross-Linking Reagents; Gels; Humans; Mice; Resveratrol; Rheology; Sepharose; Stilbenes | 2015 |
Resveratrol decreases oxidative burst capacity and alters stimulated leukocyte cytokine production in vitro.
Topics: Animals; Cytokines; Dogs; Gene Expression Regulation; Leukocytes; Phagocytosis; Respiratory Burst; Resveratrol; Stilbenes | 2015 |
Impact of lower concentrations of phytoestrogens on the effects of estradiol in breast cancer cells.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Breast; Cell Proliferation; Dose-Response Relationship, Drug; Estradiol; Female; Genistein; Humans; In Situ Nick-End Labeling; MCF-7 Cells; Phytoestrogens; Quercetin; Resveratrol; Stilbenes | 2015 |
In vivo anthelmintic activity of Carex baccans and its active principle resveratrol against Hymenolepis diminuta.
Topics: Animals; Anticestodal Agents; Carex Plant; Dose-Response Relationship, Drug; Female; Hymenolepiasis; Hymenolepis diminuta; India; Male; Parasite Egg Count; Phytotherapy; Plant Extracts; Plant Tubers; Praziquantel; Rats; Resveratrol; Stilbenes | 2015 |
Effects of resveratrol on the treatment of inflammatory response induced by severe burn.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cells, Cultured; Female; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Pseudomonas aeruginosa; Pseudomonas Infections; Resveratrol; Sirtuin 1; Stilbenes; Survival Rate; Tumor Necrosis Factor-alpha | 2015 |
Diffusion Efficiency and Bioavailability of Resveratrol Administered to Rat Brain by Different Routes: Therapeutic Implications.
Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glucuronosyltransferase; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
Nephroprotective role of resveratrol and ursolic Acid in aristolochic Acid intoxicated zebrafish.
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Aristolochic Acids; Embryo, Nonmammalian; Erythrocytes; Protective Agents; Reactive Oxygen Species; Renal Insufficiency; Resveratrol; Stilbenes; Triterpenes; Ursolic Acid; Zebrafish | 2015 |
Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzoxazoles; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Female; Glucose; Glutathione Disulfide; Glycolysis; Humans; Japan; Lactic Acid; Mice; Mice, Nude; Pentose Phosphate Pathway; Plant Extracts; Pyrimidines; Receptors, Peptide; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Treatment Outcome | 2015 |
P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Line, Tumor; Cell Proliferation; fas Receptor; Humans; Lung Neoplasms; Resveratrol; RNA-Binding Proteins; Stilbenes; Transfection | 2015 |
Biosynthetic origin of E-resveratrol accumulation in grape canes during postharvest storage.
Topics: Acyltransferases; Plant Extracts; Plant Proteins; Plant Stems; Resveratrol; Stilbenes; Temperature; Vitis; Waste Products | 2015 |
Sirt1 protects pig oocyte against in vitro aging.
Topics: Animals; Cells, Cultured; Cellular Senescence; Chromosome Aberrations; Cytoplasmic Granules; Female; Gene Expression; Microscopy, Confocal; Mitochondria; Oocytes; Resveratrol; Sirtuin 1; Spindle Apparatus; Stilbenes; Swine | 2015 |
Resveratrol induces cell apoptosis in adipocytes via AMPK activation.
Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cells, Cultured; Membrane Potential, Mitochondrial; Mice; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Effect of resveratrol on restoring spermatogenesis in experimental cryptorchid mice and analysis of related differentially expressed proteins.
Topics: Animals; Cell Shape; Cryptorchidism; Hormones; Male; Mice; Proteome; Proteomics; Resveratrol; Sperm Count; Spermatogenesis; Spermatozoa; Stilbenes; Testis; Vas Deferens | 2015 |
Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas.
Topics: 3' Untranslated Regions; Adult; Animals; Antineoplastic Agents; Binding Sites; Bone Neoplasms; Cell Line, Tumor; Cell Movement; CREB-Binding Protein; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Male; Matrix Metalloproteinase 2; Mice, SCID; MicroRNAs; Neoplasm Invasiveness; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Transcription, Genetic; Transfection; Xenograft Model Antitumor Assays; Young Adult | 2015 |
Modification of Antitumor Immunity and Tumor Microenvironment by Resveratrol in Mouse Renal Tumor Model.
Topics: Animals; Carcinoma; Cell Line, Tumor; Fas Ligand Protein; Humans; Immunologic Factors; Immunotherapy; Interferon-gamma; Interleukin-10; Interleukin-6; Kidney Neoplasms; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Resveratrol; Stilbenes; T-Lymphocytes, Regulatory; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2015 |
Influence of microemulsion-mucin interaction on the fate of microemulsions diffusing through pig gastric mucin solutions.
Topics: Administration, Oral; Animals; Biopharmaceutics; Diffusion; Drug Carriers; Drug Delivery Systems; Emulsions; Fluorescence Recovery After Photobleaching; Fluorescence Resonance Energy Transfer; Gastric Mucins; Hymecromone; Lipids; Particle Size; Resveratrol; Solutions; Stilbenes; Swine; Viscosity | 2015 |
Therapeutic effects of resveratrol in a mouse model of HDM-induced allergic asthma.
Topics: Animals; Anti-Inflammatory Agents; Antigens, Dermatophagoides; Asthma; Cell Degranulation; Cell Line; Chronic Disease; Dexamethasone; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Lung; Mast Cells; Mice; Mice, Inbred BALB C; Protein-Tyrosine Kinases; Pyroglyphidae; Resveratrol; Stilbenes; Syk Kinase; Tumor Necrosis Factor-alpha | 2015 |
Resveratrol induces apoptosis of human chronic myelogenous leukemia cells in vitro through p38 and JNK-regulated H2AX phosphorylation.
Topics: Antineoplastic Agents; Apoptosis; Dose-Response Relationship, Drug; Histones; Humans; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Time Factors; Transfection | 2015 |
Physiological levels of resveratrol metabolites are ineffective as anti-leukemia agents against Jurkat leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Death; Cell Proliferation; Glucuronides; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Resveratrol; Stilbenes | 2015 |
Simultaneous determination of isoflavones and resveratrols for adulteration detection of soybean and peanut oils by mixed-mode SPE LC-MS/MS.
Topics: Arachis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Food Contamination; Glycine max; Isoflavones; Mass Spectrometry; Plant Oils; Resveratrol; Solid Phase Extraction; Stilbenes | 2015 |
Dysregulated Ca2+ homeostasis in Fanconi anemia cells.
Topics: Acetylcysteine; Antioxidants; Calcium; Calcium-Transporting ATPases; Carbocyanines; Cell Line; Fanconi Anemia; Fanconi Anemia Complementation Group Proteins; Fibroblasts; Heterocyclic Compounds, 3-Ring; Homeostasis; Humans; Hydrogen Peroxide; Kinetics; Microscopy, Confocal; Mitochondria; Models, Biological; Resveratrol; Stilbenes; Thapsigargin | 2015 |
Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.
Topics: Aging; Animals; Astrocytes; CD11b Antigen; Cells, Cultured; Doublecortin Domain Proteins; Glial Fibrillary Acidic Protein; Hippocampus; Male; Maze Learning; Memory; Memory Disorders; Microtubule-Associated Proteins; Microvessels; Mood Disorders; Neurogenesis; Neuroglia; Neuropeptides; Rats; Rats, Inbred F344; Resveratrol; Stilbenes | 2015 |
The impact of resveratrol and hydrogen peroxide on muscle cell plasticity shows a dose-dependent interaction.
Topics: Animals; Cell Movement; Cell Plasticity; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Hydrogen Peroxide; Mice; Muscle Cells; Myoblasts; Myosin Type I; Myosins; Reactive Oxygen Species; Resveratrol; Stilbenes; Succinate Dehydrogenase | 2015 |
Curcumin and resveratrol in combination modulate drug-metabolizing enzymes as well as antioxidant indices during lung carcinogenesis in mice.
Topics: Animals; Antioxidants; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Catalase; Curcumin; Cytochrome P-450 Enzyme System; Cytochromes b5; Glutathione; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Lung; Lung Neoplasms; Male; Mice; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Synthesis and testing of novel isomeric mitochondriotropic derivatives of resveratrol and quercetin.
Topics: Animals; Cell Line, Tumor; Humans; Microscopy, Fluorescence; Mitochondria; Mitochondria, Liver; Quercetin; Rats; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2015 |
Studies with emulsion containing trans-resveratrol: in vitro release profile and ex vivo human skin permeation.
Topics: Administration, Cutaneous; Chromatography, High Pressure Liquid; Drug Delivery Systems; Drug Liberation; Emulsions; Humans; In Vitro Techniques; Kinetics; Permeability; Resveratrol; Skin Absorption; Stilbenes | 2015 |
Activation of miR-34a/SIRT1/p53 signaling contributes to cochlear hair cell apoptosis: implications for age-related hearing loss.
Topics: Acetylation; Aging; Animals; Apoptosis; Cell Line; Gene Expression; Hair Cells, Auditory; Hearing Loss, Sensorineural; Mice, Inbred C57BL; MicroRNAs; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Resveratrol interferes with the aggregation of membrane-bound human-IAPP: a molecular dynamics study.
Topics: Cell Membrane; Humans; Islet Amyloid Polypeptide; Models, Molecular; Molecular Dynamics Simulation; Resveratrol; Stilbenes; Structure-Activity Relationship | 2015 |
Resveratrol, a red wine antioxidant, reduces atrial fibrillation susceptibility in the failing heart by PI3K/AKT/eNOS signaling pathway activation.
Topics: Androstadienes; Animals; Antioxidants; Atrial Fibrillation; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Nitric Oxide Synthase Type III; Onium Compounds; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rabbits; Resveratrol; Signal Transduction; Stilbenes; Wine; Wortmannin | 2015 |
Resveratrol restores the circadian rhythmic disorder of lipid metabolism induced by high-fat diet in mice.
Topics: Animals; Body Weight; Chronobiology Disorders; Circadian Rhythm; Diet, High-Fat; Gene Expression Regulation; Lipid Metabolism; Lipids; Male; Mice, Inbred C57BL; Resveratrol; Stilbenes | 2015 |
Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages.
Topics: Acute Kidney Injury; Animals; Apoptosis; Capillary Permeability; Female; Inflammation; Kidney; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Therapeutic Potential of Resveratrol in Type I Gaucher Disease.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cells, Cultured; Fibroblasts; Gaucher Disease; Glucosylceramides; Humans; Resveratrol; Stilbenes | 2015 |
Effect of oxidant stressors and phenolic antioxidants on the ochratoxigenic fungus Aspergillus carbonarius.
Topics: Antioxidants; Aspergillus; Butylated Hydroxytoluene; Catechin; Food Contamination; Food Microbiology; Fruit; Humans; Ochratoxins; Oxidants; Oxidative Stress; Peroxiredoxins; Phenols; Plant Extracts; Resveratrol; Stilbenes; Superoxide Dismutase; Vitamin K 3; Vitis; Wine | 2016 |
Role of dietary antioxidants in human metapneumovirus infection.
Topics: Antioxidants; Cell Line; Cytokines; Dietary Supplements; Humans; Metapneumovirus; Oxidative Stress; Paramyxoviridae Infections; Quercetin; Resveratrol; Stilbenes; Virus Replication | 2015 |
Altered expression of long non-coding RNAs during genotoxic stress-induced cell death in human glioma cells.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; DNA Damage; Doxorubicin; Glioma; Humans; Necrosis; Resveratrol; RNA, Long Noncoding; Stilbenes | 2015 |
Resveratrol upregulates Egr-1 expression and activity involving extracellular signal-regulated protein kinase and ternary complex factors.
Topics: Base Sequence; Dual Specificity Phosphatase 1; Early Growth Response Protein 1; ets-Domain Protein Elk-1; Extracellular Signal-Regulated MAP Kinases; Genes, Reporter; HEK293 Cells; Humans; Molecular Sequence Data; Protein Processing, Post-Translational; Response Elements; Resveratrol; Stilbenes; Transcriptional Activation; Up-Regulation | 2015 |
Resveratrol inhibits glioma cell growth via targeting oncogenic microRNAs and multiple signaling pathways.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Glioma; MicroRNAs; Rats; Resveratrol; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2015 |
Resveratrol prevents oxidative stress-induced senescence and proliferative dysfunction by activating the AMPK-FOXO3 cascade in cultured primary human keratinocytes.
Topics: Adult; AMP-Activated Protein Kinases; Cell Proliferation; Cells, Cultured; Cellular Senescence; Enzyme Activation; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Hydrogen Peroxide; Infant; Keratinocytes; Middle Aged; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Ursolic acid and resveratrol synergize with chloroquine to reduce melanoma cell viability.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Synergism; Humans; Melanoma, Experimental; Mice; Resveratrol; Signal Transduction; Skin Neoplasms; Stilbenes; Triterpenes; Ursolic Acid | 2015 |
Mechanism of Dose-Dependent Regulation of UBE1L by Polyphenols in Human Bronchial Epithelial Cells.
Topics: Antineoplastic Agents; Bronchi; Catechin; Cell Line; Cell Survival; Curcumin; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation; Humans; Polyphenols; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; tert-Butylhydroperoxide; Ubiquitin-Activating Enzymes | 2015 |
A scalable biomimetic synthesis of resveratrol dimers and systematic evaluation of their antioxidant activities.
Topics: Antioxidants; Biological Products; Biomimetics; Cell Line; Dimerization; Humans; Indolequinones; Oxidation-Reduction; Polycyclic Compounds; Resveratrol; Stereoisomerism; Stilbenes | 2015 |
Anti-inflammatory effect of resveratrol through the suppression of NF-κB and JAK/STAT signaling pathways.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; HMGB1 Protein; I-kappa B Proteins; Interleukin-6; Janus Kinases; Lipopolysaccharides; Macrophages; Mice; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Phosphorylation; RAW 264.7 Cells; Resveratrol; RNA, Messenger; Signal Transduction; STAT Transcription Factors; Stilbenes; Transcription Factor RelA | 2015 |
Nanoparticles increase the efficacy of cancer chemopreventive agents in cells exposed to cigarette smoke condensate.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Apoptosis; Bronchial Neoplasms; Cell Line, Tumor; Humans; Isothiocyanates; Mice, Inbred Strains; Nanoparticles; Resveratrol; Smoking; Stilbenes; Tobacco Smoke Pollution | 2015 |
Resveratrol protects β amyloid-induced oxidative damage and memory associated proteins in H19-7 hippocampal neuronal cells.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Blotting, Western; Cell Line; Cytoskeletal Proteins; Disks Large Homolog 4 Protein; Hippocampus; Insulysin; Intracellular Signaling Peptides and Proteins; Lipid Peroxidation; Membrane Proteins; Nerve Tissue Proteins; Neuroprotective Agents; Peptide Fragments; Phosphorylation; Rats; Resveratrol; Stilbenes; tau Proteins | 2015 |
Resveratrol alters human endothelial cells redox state and causes mitochondrial-dependent cell death.
Topics: Cell Death; Cell Survival; Cyclosporine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2C9 Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfaphenazole | 2015 |
Riluzole- and Resveratrol-Induced Delay of Retinal Ganglion Cell Death in an Experimental Model of Glaucoma.
Topics: Animals; Antioxidants; Cell Count; Cell Survival; Disease Models, Animal; Drug Therapy, Combination; Glaucoma; Injections, Intraperitoneal; Intraocular Pressure; Male; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Retinal Ganglion Cells; Riluzole; Stilbenes; Tonometry, Ocular | 2016 |
In vitro assessment of antioxidant activity of tyrosol, resveratrol and their acetylated derivatives.
Topics: Acetylation; Antioxidants; Biphenyl Compounds; Free Radical Scavengers; Glycine max; Humans; In Vitro Techniques; Linoleic Acid; Lipid Peroxidation; Lipoxygenase Inhibitors; Oxidation-Reduction; Phenylethyl Alcohol; Picrates; Resveratrol; Serum; Stilbenes | 2015 |
Resveratrol protects against doxorubicin-induced cardiotoxicity in aged hearts through the SIRT1-USP7 axis.
Topics: Animals; Antioxidants; Apoptosis; Cardiotoxicity; Doxorubicin; Heart; Mice; Myocytes, Cardiac; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Ubiquitin-Specific Peptidase 7; Ubiquitin-Specific Proteases | 2015 |
Protective effects of resveratrol against streptozotocin-induced diabetes in rats by modulation of visfatin/sirtuin-1 pathway and glucose transporters.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Dietary Supplements; Glucose Transport Proteins, Facilitative; Hyperglycemia; Hypoglycemic Agents; Male; Malondialdehyde; Muscle, Skeletal; Nicotinamide Phosphoribosyltransferase; Oxidative Stress; Pancreas; Phytotherapy; Plant Extracts; Polyphenols; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Weight Loss | 2015 |
Effects of Resveratrol on Ovarian Morphology, Plasma Anti-Mullerian Hormone, IGF-1 Levels, and Oxidative Stress Parameters in a Rat Model of Polycystic Ovary Syndrome.
Topics: Animals; Anti-Mullerian Hormone; Antioxidants; Biomarkers; Dihydrotestosterone; Disease Models, Animal; Female; Glutathione Peroxidase; Insulin-Like Growth Factor I; Ovarian Follicle; Ovary; Oxidative Stress; Polycystic Ovary Syndrome; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cells.
Topics: Apoptosis; Cell Line, Tumor; Fibrosarcoma; Flow Cytometry; Gene Expression; Humans; Oligonucleotide Array Sequence Analysis; Resveratrol; Stilbenes | 2015 |
The combination of resveratrol and quercetin enhances the individual effects of these molecules on triacylglycerol metabolism in white adipose tissue.
Topics: Acetyl-CoA Carboxylase; Adipose Tissue, White; Animals; Blood Glucose; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Drug Synergism; Fatty Acid Synthases; Fatty Acids, Nonesterified; Hydrogen-Ion Concentration; Lipid Metabolism; Lipoprotein Lipase; Male; Organ Size; Quercetin; Rats; Rats, Wistar; Resveratrol; Sterol Esterase; Stilbenes; Triglycerides | 2016 |
The effect of resveratrol on protecting corneal epithelial cells from cytotoxicity caused by moxifloxacin and benzalkonium chloride.
Topics: Antioxidants; Benzalkonium Compounds; Cell Line; Cell Survival; Cytoprotection; Epithelial Cells; Epithelium, Corneal; Flow Cytometry; Fluoroquinolones; Humans; Luminescent Measurements; Moxifloxacin; Premedication; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol exerts growth inhibitory effects on human SZ95 sebocytes through the inactivation of the PI3-K/Akt pathway.
Topics: Cell Line, Transformed; Cell Proliferation; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Lipogenesis; Morpholines; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Resveratrol; Sebaceous Glands; Signal Transduction; Stilbenes | 2015 |
Authentication of geographical origin and crop system of grape juices by phenolic compounds and antioxidant activity using chemometrics.
Topics: Anthocyanins; Beverages; Biphenyl Compounds; Brazil; Europe; Flavonoids; Fruit; Geography; Glucosides; Humans; Organic Agriculture; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2015 |
Transcriptome and metabolome reprogramming in Vitis vinifera cv. Trincadeira berries upon infection with Botrytis cinerea.
Topics: Acyltransferases; Botrytis; Fruit; Gallic Acid; Gene Expression Profiling; Gene Expression Regulation, Plant; Glutathione Transferase; Host-Pathogen Interactions; Metabolome; Oligonucleotide Array Sequence Analysis; Phenylalanine Ammonia-Lyase; Plant Diseases; Plant Growth Regulators; Plant Proteins; Polyamines; Resveratrol; Stilbenes; Transcription Factors; Transcriptome; Vitis | 2015 |
Resveratrol increases CD68⁺ Kupffer cells colocalized with adipose differentiation-related protein and ameliorates high-fat-diet-induced fatty liver in mice.
Topics: Adipose Tissue; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Diet, High-Fat; Down-Regulation; Fatty Liver; Kupffer Cells; Liver; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Organ Size; Perilipin-2; Proteomics; Resveratrol; Stilbenes; Triglycerides; Tumor Necrosis Factor-alpha | 2015 |
Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism.
Topics: Animals; Antioxidants; Area Under Curve; Astrocytes; Brain; Carbazoles; Carbon Isotopes; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heterocyclic Compounds, 4 or More Rings; Lactic Acid; Magnetic Resonance Imaging; Male; Mitochondria; Oxidative Stress; Oxygen Consumption; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection.
Topics: Aging; Animals; Blood Pressure; Brain; Disease Models, Animal; Hypertension; Intracranial Hemorrhages; Male; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Resveratrol; Stilbenes | 2015 |
Indispensable role of endothelial nitric oxide synthase in caloric restriction-induced cardioprotection against ischemia-reperfusion injury.
Topics: Animals; Caloric Restriction; Hydralazine; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Resveratrol; Sirtuin 1; Stilbenes; Vasodilator Agents | 2015 |
Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis.
Topics: Animals; Cell Line, Tumor; Coumaric Acids; Escherichia coli; Humans; Mice; Propionates; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Ubiquinone | 2015 |
Targeting lung cancer stem-like cells with TRAIL gene armed oncolytic adenovirus.
Topics: Adenoviridae; Animals; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Inhibitors; Female; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Lung Neoplasms; Mice, Inbred BALB C; Microscopy, Fluorescence; Morpholines; Neoplastic Stem Cells; Oncolytic Virotherapy; Oncolytic Viruses; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Resveratrol improves high-fat diet induced insulin resistance by rebalancing subsarcolemmal mitochondrial oxidation and antioxidantion.
Topics: Animals; Antioxidants; Diet, High-Fat; DNA, Mitochondrial; Insulin; Insulin Resistance; Male; Mitochondria; Muscle, Skeletal; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Sirtuin 3; Stilbenes | 2015 |
Anti-inflammatory effect of resveratrol in old mice liver.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cytokines; Inflammation; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Resveratrol; RNA, Messenger; Stilbenes | 2015 |
Stress response: PARP1 911.
Topics: Animals; Antioxidants; Humans; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Resveratrol; Stilbenes; Stress, Physiological | 2015 |
Study of coumarin-resveratrol hybrids as potent antioxidant compounds.
Topics: Animals; Antioxidants; Cell Line; Coumarins; Macrophages; Mice; Resveratrol; Stilbenes | 2015 |
Resveratrol inhibits enterovirus 71 replication and pro-inflammatory cytokine secretion in rhabdosarcoma cells through blocking IKKs/NF-κB signaling pathway.
Topics: Antiviral Agents; Cytokines; Dose-Response Relationship, Drug; Enterovirus A, Human; Glucosides; I-kappa B Kinase; Inflammation; Interleukin-6; NF-kappa B; Phosphorylation; Resveratrol; Rhabdomyosarcoma; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Virus Replication | 2015 |
In vitro and in vivo inhibition of human Fanconi anemia head and neck squamous carcinoma by a phytonutrient combination.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; Dietary Supplements; Disease Models, Animal; Fanconi Anemia; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Nude; Phytochemicals; Phytotherapy; Quercetin; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes; Tea; Xenograft Model Antitumor Assays | 2015 |
Resveratrol: Challenges in translating pre-clinical findings to improved patient outcomes.
Topics: Animals; Humans; Resveratrol; Stilbenes; Translational Research, Biomedical | 2015 |
Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages.
Topics: Animals; Anti-Inflammatory Agents; B7-1 Antigen; B7-2 Antigen; Cell Line; Cell Proliferation; Cells, Cultured; Dinoprostone; Female; Gamma Rays; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Molecular Structure; NF-kappa B; Nitric Oxide; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2015 |
Resveratrol Reduces Myometrial Infiltration, Uterine Hyperactivity, and Stress Levels and Alleviates Generalized Hyperalgesia in Mice With Induced Adenomyosis.
Topics: Adenomyosis; Animals; Animals, Newborn; Behavior, Animal; Cluster Analysis; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glutamate Decarboxylase; Hyperalgesia; Mice, Inbred ICR; Myometrium; Nucleus Raphe Magnus; Pain Threshold; Phenotype; Reaction Time; Resveratrol; Stilbenes; Tamoxifen; Time Factors; Uterine Contraction; Uterus | 2015 |
Rapid determination of trans-resveratrol in vegetable oils using magnetic hydrophilic multi-walled carbon nanotubes as adsorbents followed by liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Magnetic Phenomena; Nanotubes, Carbon; Plant Oils; Resveratrol; Solid Phase Extraction; Stilbenes; Tandem Mass Spectrometry | 2015 |
The Histone Deacetylase Sirtuin 1 Is Reduced in Systemic Sclerosis and Abrogates Fibrotic Responses by Targeting Transforming Growth Factor β Signaling.
Topics: Animals; Case-Control Studies; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Humans; Mice; p300-CBP Transcription Factors; Platelet-Derived Growth Factor; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Scleroderma, Systemic; Signal Transduction; Sirtuin 1; Skin; Smad Proteins; Stilbenes; Transforming Growth Factor beta | 2015 |
Investigating the interactions of resveratrol with phospholipid vesicle bilayer and the skin: NMR studies and confocal imaging.
Topics: 3T3 Cells; Administration, Cutaneous; Animals; Liposomes; Magnetic Resonance Spectroscopy; Mice; Microscopy, Confocal; Organ Culture Techniques; Phospholipids; Resveratrol; Skin Absorption; Stilbenes; Swine | 2015 |
Screening and profiling stilbene-type natural products with angiotensin-converting enzyme inhibitory activity from Ampelopsis brevipedunculata var. hancei (Planch.) Rehder.
Topics: Ampelopsis; Angiotensin-Converting Enzyme Inhibitors; Biological Products; Chromatography, Liquid; Inhibitory Concentration 50; Molecular Docking Simulation; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2015 |
Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Female; Longevity; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Reproducibility of Results; Resveratrol; Stilbenes | 2016 |
Effects of resveratrol on benign prostatic hyperplasia by the regulation of inflammatory and apoptotic proteins.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cyclooxygenase 2; Humans; Male; Molecular Structure; Nitric Oxide Synthase Type II; Prostatic Hyperplasia; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
The effects of age and resveratrol on the hypoxic preconditioning protection against hypoxia-reperfusion injury: studies in rat hearts and human cardiomyocytes.
Topics: Age Factors; Animals; Cardiotonic Agents; Cells, Cultured; Heart Rate; Humans; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Resveratrol; Stilbenes; Ventricular Function | 2015 |
Metabolic engineering for resveratrol derivative biosynthesis in Escherichia coli.
Topics: Acyltransferases; Escherichia coli; Metabolic Engineering; Methyltransferases; Models, Molecular; Recombinant Proteins; Resveratrol; Stilbenes | 2015 |
3,4',5-trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Proliferation; Free Radical Scavengers; Humans; Inhibitory Concentration 50; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2015 |
Resveratrol Inhibits Proliferation and Induces Apoptosis of Pathological Scar Fibroblasts Through the Mechanism Involving TGF-β1/Smads Signaling Pathway.
Topics: Apoptosis; Cell Proliferation; Cicatrix; Fibroblasts; Gene Expression Regulation; Humans; Resveratrol; RNA, Messenger; Signal Transduction; Smad Proteins; Stilbenes; Transforming Growth Factor beta1 | 2015 |
An economical and efficient technology for the extraction of resveratrol from peanut (Arachis hypogaea) sprouts by multi-stage countercurrent extraction.
Topics: Arachis; Countercurrent Distribution; Resveratrol; Solid Phase Extraction; Stilbenes | 2015 |
Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions.
Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Caco-2 Cells; Emulsions; Glucuronosyltransferase; Glycerides; Humans; Intestinal Mucosa; Intestine, Small; Intestines; Male; Microsomes; Microsomes, Liver; Nanoparticles; Particle Size; Phenol; Rats; Rats, Wistar; Resveratrol; Stilbenes; Uridine Diphosphate | 2015 |
Is there room for improving the nutraceutical composition of apple?
Topics: Breeding; Dietary Supplements; Fruit; Malus; Resveratrol; Stilbenes | 2015 |
Trans-resveratrol and beta-carotene from sunscreens penetrate viable skin layers and reduce cutaneous penetration of UV-filters.
Topics: Administration, Cutaneous; Animals; Organ Culture Techniques; Resveratrol; Skin Absorption; Stilbenes; Sunscreening Agents; Swine; Ultraviolet Rays | 2015 |
Resveratrol improves the quality of pig oocytes derived from early antral follicles through sirtuin 1 activation.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Culture Media; DNA, Mitochondrial; Energy Metabolism; Enzyme Activation; Female; Granulosa Cells; In Vitro Oocyte Maturation Techniques; Lipids; Oocytes; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuins; Stilbenes; Sus scrofa | 2015 |
Overexpression of SIRT1 Induced by Resveratrol and Inhibitor of miR-204 Suppresses Activation and Proliferation of Microglia.
Topics: Animals; Cell Line; Cell Proliferation; Mice; Microglia; MicroRNAs; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
[Comparison of stilbene synthase from different plant sources for resveratrol biosynthesis].
Topics: Acyltransferases; Fallopia japonica; Recombinant Fusion Proteins; Resveratrol; Stilbenes; Vitis | 2014 |
Resveratrol downregulates type-1 glutamate transporter expression and microglia activation in the hippocampus following cerebral ischemia reperfusion in rats.
Topics: Analysis of Variance; Animals; Antigens, CD1; Antioxidants; Brain Ischemia; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Excitatory Amino Acid Transporter 2; Glial Fibrillary Acidic Protein; Hippocampus; Male; Neurons; Rats; Rats, Wistar; Reperfusion; Resveratrol; Stilbenes | 2015 |
Resveratrol synergistically augments anti-tumor effect of 5-FU in vitro and in vivo by increasing S-phase arrest and tumor apoptosis.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Flow Cytometry; Fluorouracil; Humans; Mice; Neoplasms, Experimental; Resveratrol; S Phase; Skin Neoplasms; Stilbenes | 2015 |
Intra-articular resveratrol injection prevents osteoarthritis progression in a mouse model by activating SIRT1 and thereby silencing HIF-2α.
Topics: Animals; Antioxidants; Basic Helix-Loop-Helix Transcription Factors; Cartilage, Articular; Collagen Type II; Drug Evaluation, Preclinical; Injections, Intra-Articular; Male; Matrix Metalloproteinase 13; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Osteoarthritis; Phytotherapy; Random Allocation; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Antiasthmatic effects of resveratrol in ovalbumin-induced asthma model mice involved in the upregulation of PTEN.
Topics: Airway Remodeling; Animals; Anti-Asthmatic Agents; Asthma; Cell Line; Disease Models, Animal; Female; Humans; Lung; Mice, Inbred BALB C; Ovalbumin; PTEN Phosphohydrolase; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation | 2015 |
Study on the interactions of trans-resveratrol and curcumin with bovine α-lactalbumin by spectroscopic analysis and molecular docking.
Topics: Animals; Binding Sites; Cattle; Curcumin; Hydrogen Bonding; Kinetics; Lactalbumin; Ligands; Molecular Conformation; Molecular Docking Simulation; Protein Binding; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thermodynamics; Tryptophan | 2015 |
A study of the human skin-whitening effects of resveratryl triacetate.
Topics: Adult; Cosmetics; Female; Humans; Hyperpigmentation; Melanins; Middle Aged; Pigmentation; Prodrugs; Resveratrol; Skin; Skin Lightening Preparations; Stilbenes; Sunbathing; Ultraviolet Rays | 2015 |
Effects of the polyphenol resveratrol on contractility of human term pregnant myometrium.
Topics: Female; Humans; In Vitro Techniques; Myometrium; Oxytocin; Pinacidil; Potassium Channels; Pregnancy; Resveratrol; Stilbenes; Uterine Contraction | 2015 |
The anti-inflammatory effects of resveratrol on human peripheral blood mononuclear cells are influenced by a superoxide dismutase 2 gene polymorphism.
Topics: Anti-Inflammatory Agents; Antioxidants; Cell Proliferation; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Genotype; Humans; Inflammation Mediators; Leukocytes, Mononuclear; Oxidative Stress; Phenotype; Polymorphism, Single Nucleotide; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2015 |
Obeticholic acid and resveratrol in nonalcoholic fatty liver disease: all that is gold does not glitter, not all those who wander are lost.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chenodeoxycholic Acid; Humans; Non-alcoholic Fatty Liver Disease; Randomized Controlled Trials as Topic; Receptors, Cytoplasmic and Nuclear; Resveratrol; Stilbenes | 2015 |
Nazarov cyclization of divinyl and arylvinyl epoxides: application in the synthesis of resveratrol-based natural products.
Topics: Biological Products; Cyclization; Cyclopentanes; Epoxy Compounds; Molecular Structure; Resveratrol; Stilbenes | 2015 |
Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1.
Topics: Adipocytes, Brown; Adipogenesis; Adipose Tissue, White; AMP-Activated Protein Kinases; Animals; Antioxidants; Cyclic AMP; Diet, High-Fat; Eating; Female; Gene Expression Regulation; Ion Channels; Mice; Mitochondrial Proteins; Resveratrol; Stilbenes; Uncoupling Protein 1 | 2015 |
Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Drinking; Eating; Hypertension; Inflammation; Kidney; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Resveratrol; Stilbenes | 2015 |
Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats.
Topics: Animals; Bacillus; Bacteroidetes; Diet, High-Fat; Dietary Supplements; DNA, Bacterial; Fatty Acids, Volatile; Feces; Firmicutes; Gas Chromatography-Mass Spectrometry; Gastrointestinal Microbiome; Gastrointestinal Tract; Insulin Resistance; Obesity; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sucrose; Weight Gain | 2015 |
Development and validation of a HPLC method using a monolithic column for quantification of trans-resveratrol in lipid nanoparticles for intestinal permeability studies.
Topics: Chromatography, High Pressure Liquid; Humans; Intestinal Mucosa; Models, Biological; Nanoparticles; Permeability; Resveratrol; Stilbenes | 2015 |
Biosynthesis of Resveratrol in Blastospore of the Macrofungus Tremella fuciformis.
Topics: Acyltransferases; Basidiomycota; China; Cloning, Molecular; Coenzyme A Ligases; Gastrula; Humans; Resveratrol; Stilbenes | 2015 |
SIRT1 suppresses doxorubicin-induced cardiotoxicity by regulating the oxidative stress and p38MAPK pathways.
Topics: Animals; Apoptosis; Cell Line; Doxorubicin; Gene Expression Regulation; Heart Failure; Humans; Mice; Myocytes, Cardiac; Niacinamide; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Formulation of resveratrol entrapped niosomes for topical use.
Topics: Administration, Cutaneous; Animals; Animals, Newborn; Antioxidants; Drug Compounding; Ethanol; Liposomes; Particle Size; Permeability; Resveratrol; Skin; Skin Absorption; Sonication; Stilbenes; Surface-Active Agents; Swine | 2015 |
Role of mitochondrial dysfunction in hyperglycaemia-induced coronary microvascular dysfunction: Protective role of resveratrol.
Topics: Animals; Blood Glucose; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Artery Disease; Coronary Circulation; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Humans; Isolated Heart Preparation; Male; Microcirculation; Microvessels; Mitochondria; Myocardial Contraction; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Time Factors; Vasodilation | 2015 |
Protection of injured retinal ganglion cell dendrites and unfolded protein response resolution after long-term dietary resveratrol.
Topics: Animals; Dendrites; Dietary Supplements; DNA-Binding Proteins; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Heat-Shock Proteins; Mice, Inbred C57BL; Mice, Transgenic; Optic Nerve Injuries; Protein Unfolding; Regulatory Factor X Transcription Factors; Resveratrol; Retinal Ganglion Cells; Stilbenes; Time Factors; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1 | 2015 |
Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
Topics: Animals; Cell Differentiation; Cell Line; Diabetes Mellitus, Experimental; Embryonic Stem Cells; Heterografts; Humans; Insulin-Secreting Cells; Mice; Mice, Inbred NOD; Mice, SCID; Resveratrol; Stilbenes | 2015 |
Protective effects of resveratrol against UVA-induced damage in ARPE19 cells.
Topics: Cell Line; Cell Survival; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Radiation-Protective Agents; Resveratrol; Retinal Pigment Epithelium; Stilbenes; Ultraviolet Rays | 2015 |
Resveratrol loaded gelatin nanoparticles synergistically inhibits cell cycle progression and constitutive NF-kappaB activation, and induces apoptosis in non-small cell lung cancer cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cattle; Cell Cycle; Cell Line, Tumor; Drug Synergism; Gelatin; Humans; Lung Neoplasms; Mice; Nanoparticles; NF-kappa B; Resveratrol; Stilbenes | 2015 |
Resveratrol up-regulates AMPA receptor expression via AMP-activated protein kinase-mediated protein translation.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Hippocampus; Miniature Postsynaptic Potentials; Neurons; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Rats; Receptors, AMPA; Resveratrol; Ribonucleotides; Sirtuin 1; Stilbenes; Up-Regulation | 2015 |
Nanopotentiated combination cancer therapy: Chemotherapeutic and chemosensitizer (2C approach).
Topics: Antineoplastic Agents, Phytogenic; Curcumin; Drug Delivery Systems; Drug Therapy, Combination; Flavonoids; Fluorouracil; Humans; Models, Biological; Nanoparticles; Neoplasms; Resveratrol; Stilbenes | 2015 |
Effect of phytochemical intervention on dibenzo[a,l]pyrene-induced DNA adduct formation.
Topics: Abietanes; Animals; Anthocyanins; Benzopyrenes; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; DNA Adducts; Indoles; Microsomes, Liver; Phytochemicals; Rats; Resveratrol; Stilbenes | 2015 |
The 4'-hydroxyl group of resveratrol is functionally important for direct activation of PPARα.
Topics: Animals; Gene Knockout Techniques; Hydroxides; Male; Mice; Molecular Docking Simulation; Phosphodiesterase Inhibitors; PPAR alpha; Protein Conformation; Resveratrol; Sirtuin 1; Stilbenes; Structure-Activity Relationship | 2015 |
Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile.
Topics: Animals; Antioxidants; Drug Stability; Male; Polyesters; Polyethylene Glycols; Rats, Wistar; Resveratrol; Stilbenes; Succinic Acid | 2015 |
Resveratrol Ameliorates Diabetes-Induced Cardiac Dysfunction Through AT1R-ERK/p38 MAPK Signaling Pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Heart Diseases; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Stilbenes | 2016 |
Resveratrol treatment rescues hyperleptinemia and improves hypothalamic leptin signaling programmed by maternal high-fat diet in rats.
Topics: Adipose Tissue; Animals; Body Composition; Diet, High-Fat; Female; Hyperphagia; Hypothalamus; Janus Kinase 2; Leptin; Male; Maternal Nutritional Physiological Phenomena; Obesity; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Suppressor of Cytokine Signaling 3 Protein; Weight Gain | 2016 |
Resveratrol prevents cardiovascular complications in the SHR/STZ rat by reductions in oxidative stress and inflammation.
Topics: Acetylcholine; Animals; Blood Vessels; Body Weight; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Drinking; In Vitro Techniques; Inflammation; Lipid Peroxidation; Male; Microelectrodes; Myocardial Contraction; Nitric Oxide; Nitroprusside; Norepinephrine; Oxidative Stress; Rats, Inbred SHR; Resveratrol; Stilbenes; Streptozocin; Ventricular Function | 2015 |
ω-3 Supplementation increases amyloid-β phagocytosis and resolvin D1 in patients with minor cognitive impairment.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Cholecalciferol; Cognitive Dysfunction; Dietary Supplements; Docosahexaenoic Acids; Fatty Acids, Omega-3; Female; Humans; Inflammation; Macrophages; Male; Mental Status Schedule; Middle Aged; Monocytes; Phagocytosis; Resveratrol; RNA, Messenger; Stilbenes | 2015 |
Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner.
Topics: Animals; Antioxidants; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; Enzyme Inhibitors; Female; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Islets of Langerhans; Liver; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.
Topics: Ataxia Telangiectasia Mutated Proteins; Carcinoma; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Checkpoints; Cell Division; Checkpoint Kinase 1; Checkpoint Kinase 2; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; DNA Damage; Female; G2 Phase; HeLa Cells; Humans; Phosphorylation; Protein Kinases; Quinazolines; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation; Uterine Cervical Neoplasms | 2015 |
Resveratrol suppresses vascular endothelial growth factor secretion via inhibition of CXC-chemokine receptor 4 expression in ARPE-19 cells.
Topics: Apoptosis; Cell Hypoxia; Cell Line; Cell Proliferation; Chemokine CXCL12; Cobalt; Endothelial Cells; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; NF-kappa B; Receptors, CXCR4; Resveratrol; Retinal Pigment Epithelium; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor A | 2015 |
Modulatory role of resveratrol on cytotoxic activity of cisplatin, sensitization and modification of cisplatin resistance in colorectal cancer cells.
Topics: Antioxidants; Apoptosis; Carcinogenesis; Cell Cycle; Cisplatin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Resveratrol; Stilbenes | 2015 |
Resveratrol analog piceatannol restores the palmitic acid-induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti-inflammatory and antioxidative heme oxygenase-1 in human endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Gene Expression Regulation; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Interleukin-6; Metalloporphyrins; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidants; Oxidative Stress; Palmitic Acid; Protoporphyrins; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Protective effects of resveratrol on the inhibition of hippocampal neurogenesis induced by ethanol during early postnatal life.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Ethanol; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Homeodomain Proteins; Male; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Neuroprotective Agents; Resveratrol; Stilbenes; Transcription Factor HES-1 | 2015 |
Sequential treatment with resveratrol-trolox improves development of porcine embryos derived from parthenogenetic activation and somatic cell nuclear transfer.
Topics: Animals; Chromans; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Glutathione; Nuclear Transfer Techniques; Reactive Oxygen Species; Resveratrol; Stilbenes; Swine | 2015 |
Resveratrol attenuates inflammation and oxidative stress in epididymal white adipose tissue: implications for its involvement in improving steroidogenesis in diet-induced obese mice.
Topics: Adipose Tissue, White; Animals; Blotting, Western; DNA Primers; Epididymis; Gonadal Steroid Hormones; Histological Techniques; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2015 |
Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.
Topics: Adrenoleukodystrophy; Animals; Blotting, Western; Disease Models, Animal; Humans; In Vitro Techniques; Locomotion; Mice; Mice, Mutant Strains; Oxidation-Reduction; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Effect of resveratrol and orchidectomy on the vasorelaxing influence of perivascular adipose tissue.
Topics: Adipose Tissue; Animals; Aorta, Thoracic; Disease Models, Animal; Male; Mice; Muscle, Smooth, Vascular; Orchiectomy; Platelet Aggregation Inhibitors; Resveratrol; Stilbenes; Vascular Diseases; Vasoconstriction; Vasodilation | 2016 |
Liver delipidating effect of a combination of resveratrol and quercetin in rats fed an obesogenic diet.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Diet, High-Fat; Drug Evaluation, Preclinical; Energy Intake; Gene Expression; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Obesity; Quercetin; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Resveratrol alleviates vascular inflammatory injury by inhibiting inflammasome activation in rats with hypercholesterolemia and vitamin D2 treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta, Thoracic; Atherosclerosis; Carrier Proteins; Caspase 1; Ergocalciferols; Hypercholesterolemia; Inflammasomes; Inflammation; Lipid Peroxidation; Lipids; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitamins | 2015 |
Resveratrol Regulates the Quiescence-Like Induction of Activated Stellate Cells by Modulating the PPARγ/SIRT1 Ratio.
Topics: Animals; Cell Proliferation; Fibrosis; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Kupffer Cells; Lipid Droplets; Lipogenesis; Liver; Mice; Myoblasts; PPAR gamma; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Vitamin A | 2015 |
Enhanced Production of Resveratrol, Piceatannol, Arachidin-1, and Arachidin-3 in Hairy Root Cultures of Peanut Co-treated with Methyl Jasmonate and Cyclodextrin.
Topics: Acetates; Arachis; beta-Cyclodextrins; Cell Culture Techniques; Culture Media; Cyclopentanes; Gene Expression Regulation, Plant; Hemiterpenes; Oxylipins; Plant Growth Regulators; Plant Proteins; Plant Roots; Resveratrol; Stilbenes | 2015 |
Regulation of alpha-1 acid glycoprotein synthesis by porcine hepatocytes in monolayer culture.
Topics: Acute-Phase Proteins; Animals; Animals, Suckling; Cells, Cultured; Dexamethasone; Female; Gene Expression Regulation; Haptoglobins; Hepatocytes; Interleukin-1; Interleukin-17; Interleukin-6; Oncostatin M; Orosomucoid; Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Sus scrofa; Thyroid Hormones; Tumor Necrosis Factor-alpha | 2015 |
Improving resveratrol bioaccessibility using biopolymer nanoparticles and complexes: impact of protein-carbohydrate maillard conjugation.
Topics: Biological Availability; Biopolymers; Caseins; Dextrans; Drug Carriers; Drug Delivery Systems; Gastrointestinal Tract; Humans; Maillard Reaction; Models, Biological; Nanoparticles; Resveratrol; Stilbenes | 2015 |
Cytoprotective effect of resveratrol diastereomers in CHO-K1 cells exposed to beauvericin.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cytoprotection; Depsipeptides; Lipid Peroxidation; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Effects of combining rapamycin and resveratrol on apoptosis and growth of TSC2-deficient xenograft tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Drug Therapy, Combination; Female; Gene Expression Regulation, Neoplastic; Humans; Lymphangioleiomyomatosis; Mechanistic Target of Rapamycin Complex 1; Mice, SCID; Multiprotein Complexes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Treatment Outcome; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Uterine Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Resveratrol prevents osteoporosis in ovariectomized rats by regulating microRNA-338-3p.
Topics: Animals; Antioxidants; Base Sequence; Body Weight; Bone and Bones; Cell Differentiation; Cell Line; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Down-Regulation; Female; Gene Expression Regulation; Humans; MicroRNAs; Molecular Sequence Data; Osteoblasts; Osteoporosis; Ovariectomy; Phylogeny; Rats; Rats, Wistar; Resveratrol; Sequence Alignment; Stilbenes | 2015 |
SirT1 and STAT3 protect retinal pigmented epithelium cells against oxidative stress.
Topics: Antioxidants; Apoptosis; Cell Line; Cellular Senescence; Epithelial Cells; Gene Expression Regulation; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Niacinamide; Oxidative Stress; Resveratrol; Retinal Pigment Epithelium; Signal Transduction; Sirtuin 1; STAT3 Transcription Factor; Stilbenes | 2015 |
Resveratrol Fails to Extend Life Span in the Mosquito Anopheles stephensi.
Topics: Animals; Anopheles; Carbohydrates; Feeding Behavior; Female; Longevity; Resveratrol; Stilbenes | 2015 |
Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Nerve Net; Neurons; Niacinamide; Obesity; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Streptozocin | 2015 |
Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities.
Topics: AMP-Activated Protein Kinases; Animals; Blotting, Western; Cytokines; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fructose; Gene Expression Regulation; Inflammation; Insulin Resistance; Male; Microscopy, Fluorescence; Nitric Oxide; Phosphorylation; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Vasodilation | 2016 |
Resveratrol reduces amyloid-beta (Aβ₁₋₄₂)-induced paralysis through targeting proteostasis in an Alzheimer model of Caenorhabditis elegans.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autophagy; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Disease Models, Animal; Endoplasmic Reticulum Stress; Mitochondria; Paralysis; Peptide Fragments; Proteasome Endopeptidase Complex; Proteostasis Deficiencies; Resveratrol; RNA Interference; Stilbenes; Ubiquitins; Unfolded Protein Response | 2016 |
Label-free quartz crystal microbalance with dissipation monitoring of resveratrol effect on mechanical changes and folate receptor expression levels of living MCF-7 cells: a model for screening of drugs.
Topics: Apoptosis; Biosensing Techniques; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flow Cytometry; Folate Receptors, GPI-Anchored; Humans; MCF-7 Cells; Microscopy, Fluorescence; Models, Biological; Quartz Crystal Microbalance Techniques; Resveratrol; Stilbenes; Structure-Activity Relationship | 2015 |
Resveratrol Partially Suppresses Inflammatory Events but Does not Affect Stroke Onset in Stroke-Prone Spontaneously Hypertensive Rats.
Topics: Adenylate Kinase; Animals; Antioxidants; Blood Glucose; Blood Pressure; Body Weight; Cerebrovascular Circulation; Chemokine CCL2; Endothelial Cells; Inflammation; Interleukin-1beta; Male; Rats; Rats, Inbred SHR; Resveratrol; Signal Transduction; Stilbenes; Stroke | 2015 |
Resveratrol inhibits the acetylated α-tubulin-mediated assembly of the NLRP3-inflammasome.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carrier Proteins; Caspases; Endoplasmic Reticulum; Female; Immunity, Innate; Inflammasomes; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Phytochemicals; Resveratrol; Signal Transduction; Stilbenes; Tubulin; Vitis; Wine | 2015 |
Antioxidant and anti-inflammatory agents mitigate pathology in a mouse model of pseudoachondroplasia.
Topics: Achondroplasia; Animals; Anti-Inflammatory Agents; Antioxidants; Aspirin; Cartilage Oligomeric Matrix Protein; Cell Proliferation; Chondrocytes; Disease Models, Animal; Growth Plate; Inflammation; Mice; Mutation; Resveratrol; Stilbenes | 2015 |
Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol promotes angiogenesis in a mouse model.
Topics: Animals; Aorta; Bone Marrow Cells; Cell Culture Techniques; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniques; Disease Models, Animal; HSP70 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Ischemia; Isomerism; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2015 |
The resveratrol oligomers, cis- and trans-gnetin H, from Paeonia suffruticosa seeds inhibit the growth of several human cancer cell lines.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Growth Inhibitors; Humans; Male; MCF-7 Cells; Mice; Mice, Nude; Paeonia; Resorcinols; Resveratrol; Seeds; Stereoisomerism; Stilbenes; Xenograft Model Antitumor Assays | 2015 |
NAD(+)-dependent SIRT1 deactivation has a key role on ischemia-reperfusion-induced apoptosis.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Binding Sites; Caspase 3; DNA-Binding Proteins; Enzyme Activation; Forkhead Transcription Factors; Glucose; Heat Shock Transcription Factors; Isolated Heart Preparation; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; NAD; Nerve Tissue Proteins; Promoter Regions, Genetic; Rats, Inbred WKY; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Time Factors; Transcription Factors | 2015 |
Stability and solubility of trans-resveratrol are strongly influenced by pH and temperature.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Nanofibers; Nanomedicine; Particle Size; Reproducibility of Results; Resveratrol; Solubility; Spectrophotometry, Ultraviolet; Stilbenes; Technology, Pharmaceutical; Temperature | 2015 |
Development of mucoadhesive microbeads using thiolated sodium alginate for intrapocket delivery of resveratrol.
Topics: Alginates; Animals; Antioxidants; Chemistry, Pharmaceutical; Chickens; Drug Delivery Systems; Excipients; Gingiva; Glucuronic Acid; Hexuronic Acids; Mucous Membrane; Particle Size; Resveratrol; Solubility; Stilbenes; Sulfhydryl Compounds; Thioglycolates; Tissue Adhesives | 2015 |
Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity.
Topics: Acetaminophen; Animals; Apoptosis Inducing Factor; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Drug Overdose; Endonucleases; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Liver; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidative Stress; Peroxynitrous Acid; Protein Binding; Resveratrol; Stilbenes; Tyrosine | 2015 |
Dose-related effects of chronic resveratrol administration on neurogenesis, angiogenesis, and corticosterone secretion are associated with improved spatial memory retention following global cerebral ischemia.
Topics: Adrenal Cortex; Animals; Behavior, Animal; Biomarkers; Brain Ischemia; CA1 Region, Hippocampal; Corticosterone; Dose-Response Relationship, Drug; Doublecortin Protein; Injections, Intraperitoneal; Male; Neovascularization, Physiologic; Neurogenesis; Neuronal Plasticity; Neurons; Neuroprotective Agents; Random Allocation; Rats, Wistar; Reperfusion Injury; Resveratrol; Spatial Memory; Stilbenes | 2016 |
Resveratrol-induced mitochondrial synthesis and autophagy in oocytes derived from early antral follicles of aged cows.
Topics: Abattoirs; Aging; Animals; Animals, Inbred Strains; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Biomarkers; Cattle; Female; Follicular Phase; Gene Expression Profiling; Gene Expression Regulation, Developmental; Granulosa Cells; In Vitro Oocyte Maturation Techniques; Japan; Mitochondria; Mitochondrial Dynamics; Oocytes; Ovarian Follicle; Resveratrol; Stilbenes | 2015 |
Sonic hedgehog signaling mediates resveratrol to increase proliferation of neural stem cells after oxygen-glucose deprivation/reoxygenation injury in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Female; Glucose; Hedgehog Proteins; Kruppel-Like Transcription Factors; Male; Nestin; Neural Stem Cells; Oxygen; Patched Receptors; Patched-1 Receptor; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smoothened Receptor; Stilbenes; Veratrum Alkaloids; Zinc Finger Protein GLI1 | 2015 |
Genetic diversity of stilbene metabolism in Vitis sylvestris.
Topics: Acyltransferases; Gene Expression Regulation, Plant; Genetic Variation; Genotype; Glucosides; Oomycetes; Phytoalexins; Plant Diseases; Plant Immunity; Plant Leaves; Plant Stomata; Resveratrol; Sesquiterpenes; Stilbenes; Ultraviolet Rays; Vitis | 2015 |
Discovery of the glycogen phosphorylase-modulating activity of a resveratrol glucoside by using a virtual screening protocol optimized for solvation effects.
Topics: Animals; Biological Products; Glucosides; Glycogen Phosphorylase; Rabbits; Resveratrol; Solubility; Stilbenes; Water | 2015 |
Resveratrol Represses Pokemon Expression in Human Glioma Cells.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cellular Senescence; DNA-Binding Proteins; DNA, Neoplasm; E1A-Associated p300 Protein; Gene Expression Regulation, Neoplastic; Glioma; HEK293 Cells; Histone Deacetylase 1; Humans; Promoter Regions, Genetic; Protein Binding; Protein Transport; Resveratrol; Sp1 Transcription Factor; Stilbenes; Transcription Factors | 2016 |
Transgene silencing of the Hutchinson-Gilford progeria syndrome mutation results in a reversible bone phenotype, whereas resveratrol treatment does not show overall beneficial effects.
Topics: Animals; Bone and Bones; Female; Gene Silencing; Lamin Type A; Male; Mice; Mutation; Osteocytes; Phenotype; Progeria; Resveratrol; Stilbenes; Transgenes | 2015 |
Resveratrol Improves Survival and Prolongs Life Following Hemorrhagic Shock.
Topics: Animals; Antioxidants; Disease Models, Animal; Kaplan-Meier Estimate; Male; Mortality; Myocardium; Rats; Resveratrol; Severity of Illness Index; Shock, Hemorrhagic; Stilbenes; Time Factors | 2015 |
Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage in vivo.
Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Disease Models, Animal; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; Inflammation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Pancreas; Pancreatic Diseases; Phosphorylation; Pyruvaldehyde; Resveratrol; Stilbenes | 2015 |
Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Resveratrol; Signal Transduction; Smad Proteins; Snail Family Transcription Factors; Stilbenes; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2015 |
Resveratrol food supplements: a survey on the role of individual consumer characteristics in predicting the attitudes and adoption intentions of US American and Danish respondents.
Topics: Adult; Attitude; Complementary Therapies; Denmark; Diet; Dietary Supplements; Feeding Behavior; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Health Status; Humans; Intention; Male; Middle Aged; Resveratrol; Socioeconomic Factors; Stilbenes; United States | 2015 |
A novel long noncoding RNA AK001796 acts as an oncogene and is involved in cell growth inhibition by resveratrol in lung cancer.
Topics: Animals; Cell Cycle; Cell Division; Cell Line, Tumor; Down-Regulation; Genetic Vectors; Growth Inhibitors; Humans; Lung Neoplasms; Mice, Nude; Microarray Analysis; Oncogenes; Resveratrol; RNA Interference; RNA, Long Noncoding; Stilbenes; Transfection; Tumor Stem Cell Assay | 2015 |
SIRT1 activation rescues doxorubicin-induced loss of functional competence of human cardiac progenitor cells.
Topics: Analysis of Variance; Animals; Apoptosis; Blotting, Western; Cardiomyopathies; Cells, Cultured; Disease Models, Animal; Doxorubicin; Female; Humans; Immunohistochemistry; Myocytes, Cardiac; Normal Distribution; Random Allocation; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Statistics, Nonparametric; Stem Cells; Stilbenes | 2015 |
Resveratrol attenuates CXCL11 expression induced by proinflammatory cytokines in retinal pigment epithelial cells.
Topics: Cell Line; Chemokine CXCL11; Gene Expression Regulation; Humans; Inflammation; NF-kappa B; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2015 |
Protective effect of resveratrol against caspase 3 activation in primary mouse fibroblasts.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Mice; Phosphatidylinositol 3-Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Up-Regulation | 2015 |
Improvement in the blastocyst quality and efficiency of putative embryonic stem cell line derivation from porcine embryos produced in vitro using a novel culturing system.
Topics: Animals; Blastocyst; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Embryonic Stem Cells; Female; Fertilization in Vitro; Gene Expression Profiling; Granulocyte-Macrophage Colony-Stimulating Factor; Male; Mercaptoethanol; Mice; Parthenogenesis; Resveratrol; Stilbenes; Swine | 2015 |
Resveratrol Rescues Kidney Mitochondrial Function Following Hemorrhagic Shock.
Topics: Acute Kidney Injury; Aging; Aldehydes; Animals; Antioxidants; Citrate (si)-Synthase; Hemorrhage; Kidney; Male; Mitochondria; Oxidative Stress; Rats; Rats, Long-Evans; Reactive Oxygen Species; Resuscitation; Resveratrol; Shock, Hemorrhagic; Stilbenes; Tyrosine | 2015 |
Improving effect of chronic resveratrol treatment on central monoamine synthesis and cognition in aged rats.
Topics: Aging; Animals; Body Temperature; Body Weight; Brain; Chromatography, High Pressure Liquid; Cognition; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2015 |
Synergistic Induction of Erlotinib-Mediated Apoptosis by Resveratrol in Human Non-Small-Cell Lung Cancer Cells by Down-Regulating Survivin and Up-Regulating PUMA.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; Down-Regulation; Drug Synergism; Erlotinib Hydrochloride; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Ribosomal Protein S6 Kinases; Signal Transduction; Stilbenes; Survivin; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
Inhibition of STAT3 signaling as critical molecular event in resveratrol-suppressed ovarian cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Phosphorylation; Receptors, Notch; Resveratrol; STAT3 Transcription Factor; Stilbenes; Wnt Signaling Pathway | 2015 |
Resveratrol Rescues the Impairments of Hippocampal Neurons Stimulated by Microglial Over-Activation In Vitro.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Hippocampus; Lipopolysaccharides; Mice; Microglia; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes | 2015 |
Ultradeformable liposomes as multidrug carrier of resveratrol and 5-fluorouracil for their topical delivery.
Topics: Administration, Cutaneous; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Fluorouracil; Humans; In Vitro Techniques; Liposomes; Resveratrol; Skin; Skin Absorption; Skin Neoplasms; Stilbenes | 2015 |
Comparison of biological activity of phenolic fraction from roots of Alhagi maurorum with properties of commercial phenolic extracts and resveratrol.
Topics: Antioxidants; Blood Platelets; Fabaceae; Humans; Lipid Peroxidation; Phenols; Plant Extracts; Plant Roots; Platelet Activation; Platelet Aggregation; Resveratrol; Stilbenes | 2015 |
Resveratrol-based benzoselenophenes with an enhanced antioxidant and chain breaking capacity.
Topics: Antioxidants; Caco-2 Cells; Cell Proliferation; Cells, Cultured; Humans; Keratinocytes; Kinetics; Organometallic Compounds; Resveratrol; Selenium Compounds; Stilbenes; Thermodynamics | 2015 |
Differential gene expression in liver tissues of streptozotocin-induced diabetic rats in response to resveratrol treatment.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Gene Expression Profiling; Hyperglycemia; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2015 |
[Effect of resveratrol on constrictions of human intrapulmonary arteries ex vivo].
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Humans; In Vitro Techniques; Pulmonary Artery; Resveratrol; Stilbenes; Vasoconstriction | 2015 |
Resveratrol Preconditioning Protects Against Cerebral Ischemic Injury via Nuclear Erythroid 2-Related Factor 2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Astrocytes; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Male; Mice; Mice, Knockout; Mitochondria; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Induction of c-Jun by air particulate matter (PM₁₀) of Mexico city: Participation of polycyclic aromatic hydrocarbons.
Topics: Air Pollutants; Cell Line, Tumor; Cities; Cytochrome P-450 CYP1B1; DNA Adducts; Humans; Interleukin-6; Interleukin-8; Mexico; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Proto-Oncogene Proteins c-jun; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2015 |
SIRT1 mediates a primed response to immune challenge after traumatic lung injury.
Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Immunity, Cellular; Immunoblotting; Immunohistochemistry; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Resveratrol; Ribonucleotide Reductases; RNA, Messenger; Sirtuin 1; Stilbenes | 2015 |
Use of Pollen Solid-Phase Extraction for the Determination of trans-Resveratrol in Peanut Oils.
Topics: Adsorption; Isomerism; Limit of Detection; Peanut Oil; Pinus; Plant Oils; Pollen; Resveratrol; Solid Phase Extraction; Stilbenes | 2015 |
Effect of polyphenolic phytochemicals on ectopic oxidative phosphorylation in rod outer segments of bovine retina.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzodioxoles; Caspase 3; Caspase 9; Catechin; Cattle; Curcumin; Cytochromes c; Hydrogen Peroxide; Malondialdehyde; Oxidative Phosphorylation; Oxygen Consumption; Phytochemicals; Piperidines; Polyunsaturated Alkamides; Quercetin; Resveratrol; Rod Cell Outer Segment; Stilbenes | 2015 |
Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway.
Topics: Antineoplastic Agents, Phytogenic; Autophagy; Calcium; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Male; Membrane Proteins; Neoplasm Proteins; Prostatic Neoplasms; Resveratrol; Signal Transduction; Stilbenes; Stromal Interaction Molecule 1; TOR Serine-Threonine Kinases | 2016 |
The cardioprotective effects of resveratrol in rats with simultaneous type 2 diabetes and renal hypertension.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heart Diseases; Hypertension, Renal; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
A cluster of noncoding RNAs activates the ESR1 locus during breast cancer adaptation.
Topics: Adaptation, Physiological; Base Sequence; Breast Neoplasms; Carcinoma; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; In Situ Hybridization, Fluorescence; MCF-7 Cells; Molecular Sequence Data; Resveratrol; RNA, Untranslated; Stilbenes | 2015 |
Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation.
Topics: Cell Proliferation; Cellular Senescence; DNA Damage; Fibroblasts; Gene Expression Regulation; Humans; Primary Cell Culture; Resveratrol; Sirtuin 1; Sirtuin 2; Stilbenes | 2015 |
A critical role of nicotinamide phosphoribosyltransferase in human telomerase reverse transcriptase induction by resveratrol in aortic smooth muscle cells.
Topics: Animals; Aorta; Cell Line, Tumor; Cellular Senescence; Cytokines; Dose-Response Relationship, Drug; Enzyme Induction; Female; Humans; Male; Mice, Inbred C57BL; Mitochondrial Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nicotinamide Phosphoribosyltransferase; Resveratrol; RNA Interference; Signal Transduction; Sirtuins; Stilbenes; Telomerase; Time Factors; Transfection | 2015 |
Improved neuroprotective effects of resveratrol-loaded polysorbate 80-coated poly(lactide) nanoparticles in MPTP-induced Parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Corpus Striatum; Dopaminergic Neurons; Drug Carriers; Male; Memory; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Olfactory Perception; Oxidative Stress; Parkinson Disease, Secondary; Polyesters; Polysorbates; Resveratrol; Stilbenes | 2015 |
PTEN over-expression by resveratrol in acute lymphoblastic leukemia cells along with suppression of AKT/PKB and ERK1/2 in genotoxic stress.
Topics: DNA Damage; Humans; MAP Kinase Signaling System; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Stilbenes | 2015 |
Reduction of graphene oxide by resveratrol: a novel and simple biological method for the synthesis of an effective anticancer nanotherapeutic molecule.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Graphite; Humans; Nanomedicine; Nanostructures; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes | 2015 |
Synthesis of amphiphilic resveratrol lipoconjugates and evaluation of their anticancer activity towards neuroblastoma SH-SY5Y cell line.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lipids; Molecular Structure; Neuroblastoma; Resveratrol; Stilbenes; Structure-Activity Relationship; Surface-Active Agents | 2015 |
Antitumor effect of resveratrol on chondrosarcoma cells via phosphoinositide 3-kinase/AKT and p38 mitogen-activated protein kinase pathways.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chondrocytes; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Anti-angiogenic effects of resveratrol in combination with 5-fluorouracil on B16 murine melanoma cells.
Topics: AMP-Activated Protein Kinases; Angiogenesis Inhibitors; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion Molecules; Cell Line, Tumor; Fluorouracil; Melanoma, Experimental; Mice; Microfilament Proteins; Neovascularization, Pathologic; Phosphoproteins; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2015 |
The effect of trans-resveratrol on post-stroke depression via regulation of hypothalamus-pituitary-adrenal axis.
Topics: Animals; Antidepressive Agents; Brain Ischemia; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Frontal Lobe; Hypothalamo-Hypophyseal System; Imipramine; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Pituitary-Adrenal System; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stroke | 2015 |
By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice.
Topics: Aerobiosis; Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, Tumor; Glycolysis; Hep G2 Cells; Hexokinase; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Random Allocation; Resveratrol; Stilbenes | 2015 |
Supplemental genistein, quercetin, and resveratrol intake in active duty army soldiers.
Topics: Adolescent; Adult; Antioxidants; Cross-Sectional Studies; Dietary Supplements; Female; Genistein; Humans; Male; Middle Aged; Military Personnel; Motivation; Phytochemicals; Phytoestrogens; Quercetin; Resveratrol; Stilbenes; United States; Young Adult | 2015 |
[Resveratrol inhibits hyperxia-induced cell apoptosis through up-regulating SIRT1 expression in HPAECs].
Topics: Apoptosis; Caspase 9; Cell Hypoxia; Epithelial Cells; Humans; Membrane Potential, Mitochondrial; Pulmonary Alveoli; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2015 |
Resveratrol antibacterial activity against Escherichia coli is mediated by Z-ring formation inhibition via suppression of FtsZ expression.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Blotting, Western; Chromosomes, Bacterial; Cytoskeletal Proteins; DNA Fragmentation; DNA, Fungal; Escherichia coli; Microbial Sensitivity Tests; Microscopy, Phase-Contrast; Peptide Nucleic Acids; Reactive Oxygen Species; Resveratrol; SOS Response, Genetics; Stilbenes | 2015 |
Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.
Topics: Adenylyl Cyclases; Animals; Antioxidants; Autophagy; Cyclic AMP; Dietary Supplements; Enzyme Induction; Enzyme Inhibitors; Fatty Acids, Nonesterified; Hep G2 Cells; Humans; Lipid Metabolism; Liver; Mice, 129 Strain; Microscopy, Electron, Transmission; Non-alcoholic Fatty Liver Disease; Resveratrol; RNA Interference; Second Messenger Systems; Sirtuin 1; Stilbenes | 2015 |
Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiency.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport, Active; Cells, Cultured; Chloride Channels; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; HEK293 Cells; Humans; Hypoxia; Ion Transport; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Models, Biological; Mucociliary Clearance; Nasal Mucosa; Paranasal Sinuses; Patch-Clamp Techniques; Phosphorylation; Resveratrol; Stilbenes; Swine | 2015 |
A new approach to elucidating repair reactions of resveratrol.
Topics: Aminophenols; Antioxidants; Ascorbic Acid; Chromans; Kinetics; Phenols; Resveratrol; Stilbenes; Wine | 2015 |
Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses of old mice.
Topics: Aging; Angiogenesis Inhibitors; Animals; Antioxidants; Male; Mice; Motor Activity; Organ Specificity; Oxidation-Reduction; Oxidative Stress; Physical Conditioning, Animal; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2015 |
Resveratrol induces DNA damage in colon cancer cells by poisoning topoisomerase II and activates the ATM kinase to trigger p53-dependent apoptosis.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Colonic Neoplasms; DNA Damage; DNA Topoisomerases, Type II; HCT116 Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Fluorescence quenching study of resveratrol binding to zein and gliadin: Towards a more rational approach to resveratrol encapsulation using water-insoluble proteins.
Topics: Fluorescence Resonance Energy Transfer; Gliadin; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Resveratrol; Solubility; Stilbenes; Thermodynamics; Zein | 2015 |
Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy.
Topics: Animals; Apoptosis; Cattle; Complement System Proteins; Disease Models, Animal; Glomerulonephritis, Membranous; Heme Oxygenase-1; Kidney; Kidney Glomerulus; Metalloporphyrins; Mice; Oxidative Stress; Protoporphyrins; Reactive Oxygen Species; Resveratrol; Serum Albumin; Stilbenes | 2015 |
Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1-p53 signaling pathways.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Random Allocation; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Resveratrol attenuates microvascular inflammation in sepsis via SIRT-1-Induced modulation of adhesion molecules in ob/ob mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cecum; Cell Adhesion Molecules; Female; Inflammation; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Platelet Adhesiveness; Resveratrol; Sepsis; Sirtuin 1; Stilbenes | 2015 |
Effects of long-term resveratrol-induced SIRT1 activation on insulin and apoptotic signalling in aged skeletal muscle.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Forkhead Box Protein O1; Insulin; Male; Mice; Motor Activity; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Physical Endurance; Pyruvate Dehydrogenase Complex; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Anti-fibrotic effect of trans-resveratrol on pancreatic stellate cells.
Topics: Animals; Cell Death; Cell Line; Fibronectins; Fibrosis; NF-kappa B; Pancreatic Stellate Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol-Induced Vascular Progenitor Differentiation towards Endothelial Lineage via MiR-21/Akt/β-Catenin Is Protective in Vessel Graft Models.
Topics: Animals; beta Catenin; Biomarkers; Blood Vessels; Cell Differentiation; Cell Line; Embryonic Stem Cells; Endothelial Cells; Gene Expression; Mice; MicroRNAs; Neointima; Proto-Oncogene Proteins c-akt; Resveratrol; Stem Cells; Stilbenes; Transplants | 2015 |
TCF4 Is a Molecular Target of Resveratrol in the Prevention of Colorectal Cancer.
Topics: Apoptosis; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Caco-2 Cells; Colorectal Neoplasms; Down-Regulation; Humans; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes; Transcription Factor 4; Transcription Factors | 2015 |
SIRT1 suppresses cardiomyocyte apoptosis in diabetic cardiomyopathy: An insight into endoplasmic reticulum stress response mechanism.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Diet, High-Fat; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes; Unfolded Protein Response | 2015 |
Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Gene Expression Regulation; Humans; Imiquimod; Interleukins; Male; Mice; Psoriasis; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Wall; Drugs, Chinese Herbal; Emodin; Glucosides; Methicillin-Resistant Staphylococcus aureus; Resveratrol; Rhizome; Stilbenes | 2015 |
Resveratrol Attenuated Low Ambient Temperature-Induced Myocardial Hypertrophy via Inhibiting Cardiomyocyte Apoptosis.
Topics: Animals; Apoptosis; Cardiomegaly; Caspase 3; Cold Temperature; Fibrosis; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Myocardium; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2015 |
Effect of sodium alginate addition to resveratrol on acute gouty arthritis.
Topics: Alginates; Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Gouty; Chemokine CXCL10; Colchicine; Disease Models, Animal; Drug Therapy, Combination; Glucuronic Acid; Hexuronic Acids; Interleukin-1beta; Mice; Receptors, CCR5; Resveratrol; Stilbenes; Uric Acid | 2015 |
Resveratrol attenuates spinal cord injury-induced inflammatory damage in rat lungs.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cytokines; Female; Inflammation; Lung; Lung Diseases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Spinal Cord Injuries; Stilbenes | 2015 |
Phase Behavior of Resveratrol Solid Dispersions Upon Addition to Aqueous media.
Topics: Acrylates; Crystallization; Drug Stability; Polymers; Povidone; Resveratrol; Solubility; Solutions; Spectrum Analysis, Raman; Stilbenes; Water | 2015 |
The natural phytochemical dehydroabietic acid is an anti-aging reagent that mediates the direct activation of SIRT1.
Topics: Abietanes; Adult; Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Catalytic Domain; Cells, Cultured; Enzyme Activation; Enzyme Activators; Female; Humans; Male; Middle Aged; Models, Molecular; Protein Binding; Resveratrol; Sirtuins; Stilbenes | 2015 |
Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism.
Topics: Animals; Antioxidants; Blotting, Western; Disease Models, Animal; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Fluorescent Antibody Technique; Gene Knockdown Techniques; HMGB1 Protein; Lung; Male; Mice; Mice, Inbred ICR; Mitochondria; NF-E2-Related Factor 2; Oxidative Stress; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Small Interfering; Stilbenes; Stress, Mechanical; Transfection; Ventilator-Induced Lung Injury | 2015 |
Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivo.
Topics: Administration, Oral; Animals; Antioxidants; Biotransformation; Catalase; Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Glutathione; Glutathione Peroxidase; Male; Mice; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Rhizome; Stilbenes; Superoxide Dismutase | 2015 |
Synthesis and cytotoxic activities of E-resveratrol derivatives.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Lung Neoplasms; Resveratrol; Stilbenes; Structure-Activity Relationship; Uterine Cervical Neoplasms | 2015 |
Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α).
Topics: Adipose Tissue; Animals; Energy Metabolism; Female; Glucose; Heterocyclic Compounds, 4 or More Rings; Lipid Metabolism; Liver; Male; Mice; Mice, Knockout; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Stilbenes; Transcription Factors | 2015 |
Antioxidant Treatments Recover the Alteration of Auditory-Evoked Potentials and Reduce Morphological Damage in the Inferior Colliculus after Perinatal Asphyxia in Rat.
Topics: Animals; Animals, Newborn; Antioxidants; Astrocytes; Body Weight; Disease Models, Animal; Docosahexaenoic Acids; Evoked Potentials, Auditory, Brain Stem; Gliosis; Hypoxia-Ischemia, Brain; Inferior Colliculi; Melatonin; Neurons; Neuroprotective Agents; Nicotine; Oligodendroglia; Organ Size; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling.
Topics: Acute Lung Injury; Animals; Apoptosis; Burns; Caspase 3; Cells, Cultured; Cytokines; Disease Models, Animal; Endothelial Cells; Lung; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Permeability; Rats; Rats, Sprague-Dawley; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2015 |
Evaluation of PPARα activation by known blueberry constituents.
Topics: Animals; Anthocyanins; Blueberry Plants; Catechin; Cell Line; Cricetinae; Humans; PPAR alpha; Protein Binding; Resveratrol; Stilbenes | 2016 |
Determination of naturally occurring resveratrol analog trans-4,4'-dihydroxystilbene in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study.
Topics: Animals; Chromatography, Liquid; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2015 |
Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions.
Topics: Acetylcysteine; Animals; Antioxidants; Cartilage, Articular; Cell Hypoxia; Cells, Cultured; Chondrocytes; Glutathione; Glycosaminoglycans; Horses; Hydrogen-Ion Concentration; Interleukin-1; Membrane Potential, Mitochondrial; Resveratrol; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1 | 2015 |
Ammonia-induced oxidative damage in neurons is prevented by resveratrol and lipoic acid with participation of heme oxygenase 1.
Topics: Ammonia; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Fluoresceins; Glutathione; Heme Oxygenase-1; Humans; Neurons; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Chronic treatment with resveratrol, a natural polyphenol found in grapes, alleviates oxidative stress and apoptotic cell death in ovariectomized female rats subjected to chronic cerebral hypoperfusion.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspase 3; Cerebral Cortex; Dementia, Vascular; Dietary Supplements; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Glutathione; Hippocampus; Lipid Peroxidation; Neuroprotective Agents; Ovariectomy; Oxidative Stress; Random Allocation; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Resveratrol and sildenafil synergistically improve diabetes-associated erectile dysfunction in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Blood Pressure; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diabetes Complications; Diabetes Mellitus, Experimental; Erectile Dysfunction; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Resveratrol; Second Messenger Systems; Sildenafil Citrate; Stilbenes; Sulfonamides | 2015 |
Implications of chronic daily anti-oxidant administration on the inflammatory response to intracortical microelectrodes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chronic Disease; Electrodes, Implanted; Electroencephalography; Encephalitis; Injections, Intraperitoneal; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Treatment Outcome | 2015 |
Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Topics: Antineoplastic Agents; Benzofurans; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Protein Structure, Tertiary; Resveratrol; Stilbenes; Thiophenes; Tubulin | 2015 |
Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model.
Topics: Animals; Bridged-Ring Compounds; Butadienes; Cell Line; Gap Junctions; Nitriles; Norbornanes; Phosphatidylcholines; Principal Component Analysis; Rats; Rats, Inbred F344; Resveratrol; Stilbenes; Thiocarbamates; Thiones; Type C Phospholipases | 2015 |
Shear stress-induced mitochondrial biogenesis decreases the release of microparticles from endothelial cells.
Topics: Cell-Derived Microparticles; E-Selectin; Exercise; Female; Human Umbilical Vein Endothelial Cells; Humans; Male; Middle Aged; Mitochondria; Mitochondrial Turnover; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Platelet Endothelial Cell Adhesion Molecule-1; Platelet Glycoprotein GPIb-IX Complex; Prehypertension; Regional Blood Flow; Resveratrol; Sirtuin 1; Stilbenes; Stress, Mechanical; Transcription Factors | 2015 |
Zein-Based Nanoparticles Improve the Oral Bioavailability of Resveratrol and Its Anti-inflammatory Effects in a Mouse Model of Endotoxic Shock.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Availability; Disease Models, Animal; Drug Carriers; Female; Humans; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Rats; Rats, Wistar; Resveratrol; Shock, Septic; Stilbenes; Tumor Necrosis Factor-alpha; Zein | 2015 |
Anti-apoptotic and Beneficial Metabolic Activities of Resveratrol in Type II Gaucher Disease.
Topics: Acetyl-CoA C-Acetyltransferase; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; Caspase 3; Cell Survival; Cells, Cultured; Citrate (si)-Synthase; Fibroblasts; Gaucher Disease; Glucosylceramides; Humans; Phytotherapy; Plant Extracts; Pyruvate Dehydrogenase Complex; Resveratrol; Stilbenes | 2015 |
Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes.
Topics: Acetylcysteine; ARNTL Transcription Factors; Cell Line; Cell Nucleus; Circadian Rhythm; Gene Expression; Humans; Keratinocytes; Melatonin; Niacinamide; Oxidation-Reduction; Peroxiredoxins; Protein Biosynthesis; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Transcription, Genetic | 2015 |
Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection.
Topics: AMP-Activated Protein Kinases; Dietary Supplements; Enzyme Activators; Herpes Simplex; Herpesvirus 1, Human; Humans; Neurons; Quercetin; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Assessment of the effect of prolonged forced swimming on CD-1 mice sperm morphology with and without antioxidant supplementation.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Shape; Male; Mice; Physical Conditioning, Animal; Resveratrol; Spermatozoa; Stilbenes; Swimming | 2016 |
Heterologous expression of tyrosinase (MelC2) from Streptomyces avermitilis MA4680 in E. coli and its application for ortho-hydroxylation of resveratrol to produce piceatannol.
Topics: Bacterial Proteins; Escherichia coli; Gene Expression; Hydroxylation; Monophenol Monooxygenase; Resveratrol; Stilbenes; Streptomyces | 2015 |
Resveratrol Protects Against Pathological Preterm Birth by Suppression of Macrophage-Mediated Inflammation.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cyclooxygenase 2; Disease Models, Animal; Female; Gestational Age; Inflammation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Macrophages, Peritoneal; Mice, Inbred C57BL; Pregnancy; Premature Birth; Resveratrol; Stilbenes; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Beta catenin is degraded by both caspase-3 and proteasomal activity during resveratrol-induced apoptosis in HeLa cells in a GSK3β-independent manner.
Topics: Apoptosis; beta Catenin; Caspase 3; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HeLa Cells; Humans; Proteasome Endopeptidase Complex; Resveratrol; Stilbenes | 2015 |
Phenolic compounds, organic acids and antioxidant activity of grape juices produced in industrial scale by different processes of maceration.
Topics: Anthocyanins; Antioxidants; Biflavonoids; Caffeic Acids; Catechin; Cinnamates; Food Handling; Fruit and Vegetable Juices; Gallic Acid; Phenols; Polygalacturonase; Principal Component Analysis; Proanthocyanidins; Resveratrol; Stilbenes; Temperature; Vitis | 2015 |
Resveratrol Decreases TXNIP mRNA and Protein Nuclear Expressions With an Arterial Function Improvement in Old Mice.
Topics: Animals; Aorta; Calcium; Carrier Proteins; Echocardiography, Doppler; Glucose Intolerance; Glucose Tolerance Test; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nuclear Proteins; Oxidative Stress; Phenotype; Random Allocation; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Thioredoxins | 2016 |
Resveratrol Inhibits the Invasion of Glioblastoma-Initiating Cells via Down-Regulation of the PI3K/Akt/NF-κB Signaling Pathway.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Survival; Dacarbazine; Down-Regulation; Glioblastoma; Humans; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Transplantation; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Temozolomide | 2015 |
Resveratrol suppresses persistent airway inflammation and hyperresponsivess might partially via nerve growth factor in respiratory syncytial virus-infected mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain-Derived Neurotrophic Factor; Bronchoalveolar Lavage Fluid; Female; Interferon-gamma; Lung; Mice; Mice, Inbred BALB C; Nerve Growth Factor; Pneumonia; Respiratory Function Tests; Respiratory Hypersensitivity; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Resveratrol; RNA, Viral; Stilbenes | 2015 |
Resveratrol amplifies BMP-4-stimulated osteoprotegerin synthesis via p38 MAP kinase in osteoblasts.
Topics: Animals; Bone Density Conservation Agents; Bone Morphogenetic Protein 4; Cell Line; Mice; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes | 2015 |
Structural modification of resveratrol leads to increased anti-tumor activity, but causes profound changes in the mode of action.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Caco-2 Cells; Cell Cycle Checkpoints; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hep G2 Cells; HT29 Cells; Humans; Liver Neoplasms; Microtubules; Molecular Structure; Resveratrol; RNA Interference; Sirtuin 1; Stilbenes; Structure-Activity Relationship; Transfection; Tubulin Modulators | 2015 |
Pathological changes in hippocampal neuronal circuits underlie age-associated neurodegeneration and memory loss: positive clue toward SAD.
Topics: Aging; Animals; Frontal Lobe; Hippocampus; Male; Neocortex; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Spatial Learning; Spatial Memory; Stilbenes | 2015 |
Resveratrol induces apoptosis of leukemia cell line K562 by modulation of sphingosine kinase-1 pathway.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Cell Membrane; Cell Proliferation; Ceramides; Cytosol; Dose-Response Relationship, Drug; Humans; K562 Cells; Leukemia, Myeloid; Lysophospholipids; Phosphotransferases (Alcohol Group Acceptor); Protein Transport; Resveratrol; Signal Transduction; Sphingosine; Stilbenes; Time Factors | 2015 |
Resveratrol Enhances Etoposide-Induced Cytotoxicity through Down-Regulating ERK1/2 and AKT-Mediated X-ray Repair Cross-Complement Group 1 (XRCC1) Protein Expression in Human Non-Small-Cell Lung Cancer Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Time Factors; Transfection; X-ray Repair Cross Complementing Protein 1 | 2015 |
Resveratrol ameliorates depressive-like behavior in repeated corticosterone-induced depression in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corticosterone; Depression; Gene Expression Regulation; Hippocampus; Male; Mice; Resveratrol; Stilbenes | 2015 |
Spectroscopic study on the interaction of resveratrol and pterostilbene with human serum albumin.
Topics: Binding Sites; Humans; Molecular Docking Simulation; Protein Binding; Protein Conformation; Resveratrol; Serum Albumin; Spectrum Analysis; Stilbenes | 2015 |
Design, synthesis and biological evaluation of paralleled Aza resveratrol-chalcone compounds as potential anti-inflammatory agents for the treatment of acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Aza Compounds; Cell Line; Chalcones; Humans; Interleukin-6; Lipopolysaccharides; Lung; Macrophages; Mice; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
A natural product, resveratrol, protects against high-glucose-induced developmental damage in chicken embryo.
Topics: Animals; Biological Products; Chickens; Glucose; Molecular Structure; Neuroprotective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol Upregulates Cardiac SDF-1 in Mice with Acute Myocardial Infarction through the Deacetylation of Cardiac p53.
Topics: Acetylation; Animals; Cell Hypoxia; Chemokine CXCL12; Fibrosis; Gene Silencing; Heart Function Tests; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Ultrasonography; Up-Regulation | 2015 |
Resveratrol attenuates high glucose-induced oxidative stress and cardiomyocyte apoptosis through AMPK.
Topics: Adenylate Kinase; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Gene Expression; Glucose; Myocytes, Cardiac; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; rac1 GTP-Binding Protein; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats.
Topics: Animals; Diet, High-Fat; Dyslipidemias; Endoplasmic Reticulum Stress; Gene Expression; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing's sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Caspases; Cell Proliferation; Etoposide; Flow Cytometry; Heterocyclic Compounds, 4 or More Rings; Humans; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma, Ewing; Sirtuin 1; Stilbenes; Tumor Cells, Cultured; Vincristine | 2016 |
SIRT1 Suppresses Human T-Cell Leukemia Virus Type 1 Transcription.
Topics: Chromatin Immunoprecipitation; Gene Expression Regulation, Viral; HEK293 Cells; Human T-lymphotropic virus 1; Humans; Jurkat Cells; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sirtuin 1; Stilbenes; Terminal Repeat Sequences; Virion | 2015 |
Quercetin and Resveratrol Decrease the Inflammatory and Oxidative Responses in Human Ocular Surface Epithelial Cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cells, Cultured; Chemokine CXCL10; Conjunctiva; Drug Combinations; Epithelium, Corneal; Humans; Interleukin-6; Interleukin-8; Quercetin; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Ultraviolet Rays; Vascular Endothelial Growth Factor A | 2015 |
Apoptotic Cell Death Induced by Resveratrol Is Partially Mediated by the Autophagy Pathway in Human Ovarian Cancer Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Autophagy-Related Protein 5; Caspase 3; Cell Line, Tumor; Chloroquine; Female; Humans; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Ovarian Neoplasms; Oxidative Stress; Reactive Oxygen Species; Resveratrol; RNA Interference; RNA, Small Interfering; Stilbenes | 2015 |
Resveratrol improves hepatic insulin signaling and reduces the inflammatory response in streptozotocin-induced diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Inflammation; Insulin; Liver; Male; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Streptozocin | 2015 |
Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway.
Topics: Animals; Cyclosporine; Disease Models, Animal; Glucosides; Hepatocytes; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Shock, Hemorrhagic; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2015 |
Creating Space for Large Acceptors: Rational Biocatalyst Design for Resveratrol Glycosylation in an Aqueous System.
Topics: Binding Sites; Biocatalysis; Catalytic Domain; Enzymes; Glucosyltransferases; Glycosylation; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Resveratrol; Stilbenes; Substrate Specificity; Thermoanaerobacterium; Water | 2015 |
Effect of resveratrol on Treg/Th17 signaling and ulcerative colitis treatment in mice.
Topics: Animals; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Male; Mice, Inbred BALB C; Resveratrol; Signal Transduction; Spleen; STAT3 Transcription Factor; Stilbenes; T-Lymphocytes, Regulatory; Th17 Cells; Time Factors; TOR Serine-Threonine Kinases | 2015 |
Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload.
Topics: Acetylation; Animals; Antioxidants; Apoptosis; Chronic Disease; Disease Models, Animal; Forkhead Box Protein O1; Forkhead Transcription Factors; Hemochromatosis; Iron; Iron Overload; Liver Diseases; Mice; Models, Genetic; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Treatment Outcome | 2016 |
Resveratrol Reduces Morphologic Changes in the Myenteric Plexus and Oxidative Stress in the Ileum in Rats with Ischemia/Reperfusion Injury.
Topics: Administration, Oral; Animals; Antioxidants; Disease Models, Animal; Glucosephosphate Dehydrogenase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Ileal Diseases; Ileum; Lipid Peroxidation; Male; Myenteric Plexus; Neuroprotective Agents; Nitrergic Neurons; Oxidative Stress; Protein Carbonylation; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2015 |
Resveratrol reverses morphine-induced neuroinflammation in morphine-tolerant rats by reversal HDAC1 expression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Drug Tolerance; Histone Deacetylase 1; Injections, Spinal; Male; Morphine; Neuralgia; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Resveratrol; Spinal Cord; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol regulates oxidative biomarkers and antioxidant enzymes in the brain of streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Frontal Lobe; Gene Expression Regulation, Enzymologic; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2016 |
Promoter methylation-independent reactivation of PAX1 by curcumin and resveratrol is mediated by UHRF1.
Topics: CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Curcumin; DNA Methylation; Gene Expression Profiling; Gene Expression Regulation; Humans; Paired Box Transcription Factors; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Transcriptional Activation; Ubiquitin-Protein Ligases | 2016 |
Effects of a grape-supplemented diet on proliferation and Wnt signaling in the colonic mucosa are greatest for those over age 50 and with high arginine consumption.
Topics: AC133 Antigen; Adolescent; Adult; Antigens, CD; Arginine; Axin Protein; Biomarkers; Body Mass Index; Cell Proliferation; Colon; Colonic Neoplasms; Cyclin D1; Diet; Female; Glycoproteins; Humans; Intestinal Mucosa; Linear Models; Male; Mental Recall; Middle Aged; Peptides; Proto-Oncogene Proteins c-myc; Resveratrol; Stilbenes; Vitis; Wnt Signaling Pathway; Young Adult | 2015 |
Trans-Resveratrol Induces Apoptosis through ROS-Triggered Mitochondria-Dependent Pathways in A549 Human Lung Adenocarcinoma Epithelial Cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Survival; Epithelial Cells; Fluoresceins; Humans; Lung Neoplasms; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes; Tetrazolium Salts; Thiazoles | 2015 |
Resveratrol Protects Hippocampal Astrocytes Against LPS-Induced Neurotoxicity Through HO-1, p38 and ERK Pathways.
Topics: Animals; Astrocytes; Cells, Cultured; Heme Oxygenase (Decyclizing); Hippocampus; Lipopolysaccharides; Male; MAP Kinase Signaling System; Neuroprotective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Resveratrol increases glycolytic flux in Saccharomyces cerevisiae via a SNF1-dependet mechanism.
Topics: Glycolysis; Hexokinase; Mitochondria; Oxygen Consumption; Phosphofructokinase-1; Protein Serine-Threonine Kinases; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stilbenes; Transcription, Genetic | 2015 |
Construction, expression, and characterization of Arabidopsis thaliana 4CL and Arachis hypogaea RS fusion gene 4CL::RS in Escherichia coli.
Topics: Acyltransferases; Arabidopsis; Arachis; Biosynthetic Pathways; Cloning, Molecular; Coenzyme A Ligases; Coumaric Acids; Escherichia coli; Plant Proteins; Propionates; Recombinant Fusion Proteins; Resveratrol; Stilbenes | 2015 |
Locating the binding sites of antioxidants resveratrol, genistein and curcumin with tRNA.
Topics: Antioxidants; Base Pairing; Binding Sites; Curcumin; Genistein; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Resveratrol; RNA, Transfer; Stilbenes; Thermodynamics | 2015 |
The Phytoalexin Resveratrol Ameliorates Ochratoxin A Toxicity in Human Embryonic Kidney (HEK293) Cells.
Topics: Apoptosis; Aspergillus; ATP-Dependent Proteases; Balkan Nephropathy; DNA Damage; DNA Glycosylases; Food Microbiology; HEK293 Cells; Humans; Mitochondrial Proteins; Ochratoxins; Oxidative Stress; Penicillium; Phytoalexins; Reactive Oxygen Species; Resveratrol; Sesquiterpenes; Stilbenes | 2015 |
Cytotoxicity of the mycotoxins deoxynivalenol and ochratoxin A on Caco-2 cell line in presence of resveratrol.
Topics: Antioxidants; Caco-2 Cells; Cell Survival; Drug Interactions; Humans; Ochratoxins; Reactive Oxygen Species; Resveratrol; Stilbenes; Trichothecenes | 2015 |
Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.
Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Cell Nucleus; Cell Proliferation; Cytosol; Female; Inflammation; Male; Mice; Mice, Inbred ICR; Protein Binding; Resveratrol; Signal Transduction; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2015 |
Inhibition of amyloid fibrillation and cytotoxicity of lysozyme fibrillation products by polyphenols.
Topics: Amyloid; Animals; Antioxidants; Cell Shape; Cell Survival; Cinnamates; Depsides; Drug Evaluation, Preclinical; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Muramidase; PC12 Cells; Protein Aggregation, Pathological; Protein Stability; Protein Structure, Secondary; Rats; Resveratrol; Rosmarinic Acid; Stilbenes | 2015 |
Resveratrol derivative-rich melinjo (Gnetum gnemon L.) seed extract improves obesity and survival of C57BL/6 mice fed a high-fat diet.
Topics: Animals; Diet, High-Fat; Gnetum; Insulin; Male; Mice; Mice, Inbred C57BL; Motor Activity; Obesity; Plant Extracts; Resveratrol; Seeds; Stilbenes; Survival Analysis | 2015 |
Antimicrobial mechanism of resveratrol-trans-dihydrodimer produced from peroxidase-catalyzed oxidation of resveratrol.
Topics: Anti-Infective Agents; DNA, Bacterial; Escherichia coli; Gene Expression Profiling; Glycine max; Gram-Positive Bacteria; Membrane Potentials; Microbial Sensitivity Tests; Oxidation-Reduction; Peroxidase; Resveratrol; Stilbenes | 2015 |
Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol.
Topics: Crystallization; Enzyme Activation; Models, Molecular; Protein Structure, Tertiary; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Sulfated and Glucuronated trans-Resveratrol Metabolites Regulate Chemokines and Sirtuin-1 Expression in U-937 Macrophages.
Topics: Anti-Inflammatory Agents; Cell Line; Chemokines; Gene Expression Regulation; Glucuronides; Humans; Lipopolysaccharides; Macrophage Activation; Macrophages; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Sulfates | 2015 |
Analysis of Potential Binding Sites of 3,5,4'-Trihydroxystilbene (Resveratrol) and trans-3,3',5,5'-Tetrahydroxy-4'-methoxystilbene (THMS) to the GAPDH Molecule Using a Computational Ligand-Docking Method: Structural and Functional Changes in GAPDH Induced
Topics: Antioxidants; Catalytic Domain; Glyceraldehyde-3-Phosphate Dehydrogenases; Ligands; Molecular Docking Simulation; Polyphenols; Resveratrol; Stilbenes; Superoxides; Tryptophan | 2015 |
Resveratrol via activation of AMPK lowers blood pressure in DOCA-salt hypertensive mice.
Topics: AMP-Activated Protein Kinases; Animals; Anticarcinogenic Agents; Blood Pressure; Desoxycorticosterone Acetate; Disease Models, Animal; Enzyme Activation; Hypertension; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Resveratrol; Stilbenes; Vasoconstriction; Vasodilator Agents | 2015 |
In vitro biological activity of resveratrol using a novel inhalable resveratrol spray-dried formulation.
Topics: Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Desiccation; Dry Powder Inhalers; Epithelial Cells; Free Radical Scavengers; Humans; Interleukin-8; Lipopolysaccharides; Particle Size; Pulmonary Disease, Chronic Obstructive; Resveratrol; Stilbenes; Stress, Physiological; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2015 |
Resveratrol-salicylate derivatives as selective DNMT3 inhibitors and anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3B; Enzyme Activation; Hep G2 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Protein Binding; Resveratrol; Salicylates; Stilbenes | 2016 |
Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity.
Topics: AMP-Activated Protein Kinases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colorectal Neoplasms; Cyclic AMP Response Element-Binding Protein; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; eIF-2 Kinase; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; I-kappa B Proteins; NF-KappaB Inhibitor alpha; Organoplatinum Compounds; Oxaliplatin; Resveratrol; Signal Transduction; Stilbenes; Transcriptional Activation | 2015 |
Inhibition of human chronic myelogenous leukemia K562 cell growth following combination treatment with resveratrol and imatinib mesylate.
Topics: Apoptosis; Cell Cycle; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Resveratrol; Stilbenes | 2015 |
Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
Topics: Acetylcysteine; Animals; Antioxidants; Biomarkers; Choline Deficiency; Cytoprotection; Disease Models, Animal; Hypolipidemic Agents; Lipids; Liver; Male; Methionine; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Ursodeoxycholic Acid | 2016 |
A Resveratrol Analogue Promotes ERKMAPK-Dependent Stat3 Serine and Tyrosine Phosphorylation Alterations and Antitumor Effects In Vitro against Human Tumor Cells.
Topics: Acetates; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; MAP Kinase Signaling System; Phosphorylation; Resveratrol; Serine; STAT3 Transcription Factor; Stilbenes; Tyrosine | 2015 |
Resveratrol- and α-viniferin-induced alterations of acetylcholinesterase and nitric oxide synthase in Raillietina echinobothrida.
Topics: Acetylcholinesterase; Animals; Anthelmintics; Benzofurans; Cestoda; Cholinesterase Inhibitors; India; Nitric Oxide; Nitric Oxide Synthase; Plant Extracts; Praziquantel; Resveratrol; Stilbenes | 2015 |
Probing the position of resveratrol in lipid bilayers: A neutron reflectivity study.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Cholesterol; Lipid Bilayers; Neutrons; Resveratrol; Stilbenes; Surface Properties | 2015 |
Influence of high fat diet and resveratrol supplementation on placental fatty acid uptake in the Japanese macaque.
Topics: AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Dietary Supplements; Fatty Acids; Female; Fetus; Macaca; Maternal-Fetal Exchange; Phosphorylation; Placenta; Pregnancy; Resveratrol; Stilbenes | 2015 |
[Resveratrol inhibits cell proliferation and up-regulates MICA/B expression in human colon cancer stem cells].
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; Histocompatibility Antigens Class I; Humans; Neoplastic Stem Cells; Resting Phase, Cell Cycle; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Up-Regulation | 2015 |
Resveratrol prevents cadmium activation of Erk1/2 and JNK pathways from neuronal cell death via protein phosphatases 2A and 5.
Topics: Animals; Cadmium; Cell Death; Cell Survival; Enzyme Activation; Humans; MAP Kinase Signaling System; Neurons; Nuclear Proteins; PC12 Cells; Phosphoprotein Phosphatases; Protein Phosphatase 2; Rats; Resveratrol; Stilbenes | 2015 |
Biological and computational evaluation of resveratrol inhibitors against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Cell Death; Cell Line; Dose-Response Relationship, Drug; Mice; Molecular Dynamics Simulation; Molecular Structure; Neurons; Oxidative Stress; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
Transcriptome analysis of the biofilm formed by methicillin-susceptible Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biofilms; Gene Expression Profiling; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Resveratrol; RNA, Bacterial; Sequence Analysis, RNA; Staphylococcus aureus; Stilbenes; Transcriptome; Triterpenes; Ursolic Acid; Vancomycin | 2015 |
Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; DNA Damage; Epoxy Compounds; HL-60 Cells; Humans; Male; Methyl Methanesulfonate; Mice; Micronucleus Tests; Mitomycin; Procarbazine; Quinolones; Resveratrol; Stilbenes | 2016 |
Modifying Choroidal Neovascularization Development with a Nutritional Supplement in Mice.
Topics: Animals; Carrier Proteins; Choroid; Choroidal Neovascularization; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Fatty Acids, Omega-3; Fluorescein Angiography; Intravitreal Injections; Lutein; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Minerals; NLR Family, Pyrin Domain-Containing 3 Protein; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A; Vitamins | 2015 |
The chemomodulatory effects of resveratrol and didox on herceptin cytotoxicity in breast cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Receptor, ErbB-2; Resveratrol; Stilbenes; Trastuzumab | 2015 |
Metabolic faecal fingerprinting of trans-resveratrol and quercetin following a high-fat sucrose dietary model using liquid chromatography coupled to high-resolution mass spectrometry.
Topics: Animals; Chromatography, Liquid; Dietary Fats; Dietary Sucrose; Dietary Supplements; Feces; Female; Male; Mass Spectrometry; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Photostability evaluation of five UV-filters, trans-resveratrol and beta-carotene in sunscreens.
Topics: Acrylates; Benzoates; beta Carotene; Chromatography, High Pressure Liquid; Cinnamates; Drug Stability; Gas Chromatography-Mass Spectrometry; Phenols; Photolysis; Propiophenones; Resveratrol; Singlet Oxygen; Spectrophotometry, Ultraviolet; Stilbenes; Sunscreening Agents; Superoxides; Triazines; Ultraviolet Rays | 2015 |
Resveratrol Preconditioning Induces a Novel Extended Window of Ischemic Tolerance in the Mouse Brain.
Topics: Animals; Brain; Brain Ischemia; Drug Administration Schedule; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Resveratrol; Stilbenes; Time Factors | 2015 |
Combinatorial resveratrol and quercetin polymeric micelles mitigate doxorubicin induced cardiotoxicity in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Cell Line; Cell Line, Tumor; Doxorubicin; Drug Carriers; Female; Heart; Humans; Male; Micelles; Myocytes, Cardiac; Poloxamer; Quercetin; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells.
Topics: Angiopoietins; Animals; Antioxidants; Fetal Blood; Graft Survival; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Insulin-Like Growth Factor Binding Protein 2; Interleukin Receptor Common gamma Subunit; Interleukin-6; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Primary Cell Culture; Resveratrol; Stem Cell Factor; Stilbenes; Thrombopoietin; Transplantation, Heterologous; Vascular Endothelial Growth Factor Receptor-1 | 2015 |
Comparison of the anti-diabetic effects of resveratrol, gliclazide and losartan in streptozotocin-induced experimental diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gliclazide; Glycated Hemoglobin; Hypoglycemic Agents; Losartan; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Resveratrol Ameliorates Pressure Overload-induced Cardiac Dysfunction and Attenuates Autophagy in Rats.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Autophagy; Blotting, Western; Cardiotonic Agents; Disease Models, Animal; Heart Failure; Heart Function Tests; Hypertension; Male; Myocardium; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
Biochemical and Histopathological Investigation of Resveratrol, Gliclazide, and Losartan Protective Effects on Renal Damage in a Diabetic Rat Model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Gliclazide; Hypoglycemic Agents; Immunohistochemistry; Kidney; Losartan; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Dendrimer nanotechnology for enhanced formulation and controlled delivery of resveratrol.
Topics: Animals; Biological Availability; Chemistry, Pharmaceutical; Dendrimers; Drug Stability; Humans; Resveratrol; Solubility; Solutions; Stilbenes | 2015 |
Resveratrol attenuates hyperoxia-induced oxidative stress, inflammation and fibrosis and suppresses Wnt/β-catenin signalling in lungs of neonatal rats.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Cell Hypoxia; Cytoprotection; Female; Inflammation; Lung; Oxidative Stress; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wnt Signaling Pathway | 2015 |
SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization.
Topics: Cell Line; Choroidal Neovascularization; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Phosphorylation; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2015 |
Resveratrol Derivative-Rich Melinjo Seed Extract Attenuates Skin Atrophy in Sod1-Deficient Mice.
Topics: Animals; Benzofurans; Cell Line; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Gnetum; Mice; Mice, Knockout; Plant Extracts; Resveratrol; Seeds; Sirtuin 1; Skin; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Tumor Suppressor Protein p53 | 2015 |
Antioxidant potential of CORM-A1 and resveratrol during TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Boranes; Carbonates; Cell Line; Cycloheximide; Cytoprotection; Epithelial Cells; Intestinal Mucosa; Membrane Potential, Mitochondrial; Mice; Mitochondria; NADPH Oxidases; Oxidative Stress; Oxygen Consumption; Resveratrol; Stilbenes; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Resveratrol ameliorates high glucose-induced oxidative stress injury in human umbilical vein endothelial cells by activating AMPK.
Topics: Adenylate Kinase; Cells, Cultured; Diabetic Angiopathies; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Activators; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Malondialdehyde; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Structural modeling for DNA binding to antioxidants resveratrol, genistein and curcumin.
Topics: Antioxidants; Binding Sites; Circular Dichroism; Curcumin; DNA; DNA Adducts; Genistein; Intercalating Agents; Models, Molecular; Molecular Docking Simulation; Nucleic Acid Conformation; Resveratrol; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2015 |
Resveratrol inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cell line C666-1 through AMPK activation.
Topics: AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Activation; Humans; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Nasopharyngeal Neoplasms; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases | 2015 |
Resveratrol inhibits dysfunction of dendritic cells from chronic obstructive pulmonary disease patients through promoting miR-34.
Topics: B7-1 Antigen; B7-2 Antigen; Biomarkers; Dendritic Cells; Dose-Response Relationship, Drug; Female; HEK293 Cells; Humans; Interferon-gamma; Male; MicroRNAs; Middle Aged; Pulmonary Disease, Chronic Obstructive; Resveratrol; Signal Transduction; Stilbenes; Transfection; Up-Regulation | 2015 |
Xanthohumol impairs glucose uptake by a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) and impacts the process of placentation.
Topics: Biological Transport; Cell Division; Cell Line, Transformed; Cell Movement; Cytochalasin B; Deoxyglucose; Dexamethasone; Female; Flavonoids; Glucose; Glucose Transport Proteins, Facilitative; Humans; Illicit Drugs; Melatonin; Phloretin; Phlorhizin; Placentation; Polyphenols; Pregnancy; Pregnancy Trimester, First; Propiophenones; Protein-Tyrosine Kinases; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Trophoblasts | 2015 |
Effect of substituted stilbenes on platelet function.
Topics: Blood Platelets; Humans; Nitric Oxide; Platelet Aggregation; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Synthesis of Resveratrol Glycosides by Plant Glucosyltransferase and Cyclodextrin Glucanotransferase and Their Neuroprotective Activity.
Topics: Biocatalysis; Glucosyltransferases; Glycosides; Neuroprotective Agents; Phytolacca americana; Plant Proteins; Resveratrol; Stilbenes | 2015 |
Resveratrol prevents doxorubicin-induced cardiotoxicity in H9c2 cells through the inhibition of endoplasmic reticulum stress and the activation of the Sirt1 pathway.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Cardiotoxicity; Cell Line; Cell Survival; Doxorubicin; Endoplasmic Reticulum Stress; Myoblasts; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity.
Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Aspirin; Caspase 3; Cell Cycle; Cell Line, Tumor; Cyclins; Enzyme Activation; Female; Humans; Intestinal Absorption; Mice; Mice, Inbred C57BL; Prodrugs; Resveratrol; Stilbenes | 2015 |
Protective effect of resveratrol against oxidative damage to ovarian reserve in female Sprague-Dawley rats.
Topics: Animals; Anti-Mullerian Hormone; Antineoplastic Agents; Antioxidants; Cisplatin; Female; Ovarian Follicle; Ovarian Reserve; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Up-Regulation | 2015 |
A novel approach to arthritis treatment based on resveratrol and curcumin co-encapsulated in lipid-core nanocapsules: In vivo studies.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Curcumin; Drug Carriers; Foot Joints; Grape Seed Extract; Hexoses; Injections, Intraperitoneal; Male; Nanocapsules; Polyesters; Polysorbates; Rats, Wistar; Resveratrol; Stilbenes; Treatment Outcome | 2015 |
Effects of sulfamethoxazole-trimethoprim associated to resveratrol on its free form and complexed with 2-hydroxypropyl-β-cyclodextrin on cytokines levels of mice infected by Toxoplasma gondii.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antiprotozoal Agents; beta-Cyclodextrins; Brain; Cytokines; Immunologic Factors; Mice, Inbred BALB C; Resveratrol; Serum; Stilbenes; Toxoplasma; Toxoplasmosis, Animal; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2015 |
Resveratrol inhibits TIGAR to promote ROS induced apoptosis and autophagy.
Topics: Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; Drug Synergism; Fluorescent Antibody Technique; Humans; Intracellular Signaling Peptides and Proteins; Microscopy, Confocal; Phosphoric Monoester Hydrolases; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection | 2015 |
Resveratrol and curcumin synergistically induces apoptosis in cigarette smoke condensate transformed breast epithelial cells through a p21(Waf1/Cip1) mediated inhibition of Hh-Gli signaling.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Cell Line; Cell Transformation, Neoplastic; Curcumin; Cyclin-Dependent Kinase Inhibitor p21; Drug Synergism; Epithelial Cells; Female; Hedgehog Proteins; Humans; Immunoblotting; Mice, Inbred BALB C; Microscopy, Fluorescence; Nicotiana; Resveratrol; RNA Interference; Signal Transduction; Smoke; Stilbenes; Transcription Factors; Xenograft Model Antitumor Assays; Zinc Finger Protein GLI1 | 2015 |
Glucoregulatory Relevance of Small Intestinal Nutrient Sensing in Physiology, Bariatric Surgery, and Pharmacology.
Topics: Animals; Bariatric Surgery; Blood Glucose; Brain; Glucose; Glycemic Load; Humans; Hypoglycemic Agents; Intestine, Small; Liver; Metformin; Nutritional Physiological Phenomena; Resveratrol; Stilbenes | 2015 |
Epigenetic potential of resveratrol and analogs in preclinical models of prostate cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylases; Humans; Male; MicroRNAs; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Stilbenes; Trans-Activators; Xenograft Model Antitumor Assays | 2015 |
Skin penetration behavior of lipid-core nanocapsules for simultaneous delivery of resveratrol and curcumin.
Topics: Cell Survival; Cells, Cultured; Curcumin; Drug Carriers; Drug Liberation; Fibroblasts; Grape Seed Extract; Hexoses; Humans; In Vitro Techniques; Nanocapsules; Oils; Polyesters; Polyphenols; Resveratrol; Skin Absorption; Stilbenes | 2015 |
Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice.
Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Autophagy; Colorectal Neoplasms; Diet, High-Fat; Dose-Response Relationship, Drug; Humans; Mice; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2015 |
Resveratrol-downregulated phosphorylated liver kinase B1 is involved in senescence of acute myeloid leukemia stem cells.
Topics: AMP-Activated Protein Kinase Kinases; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Phosphorylation; Protein Serine-Threonine Kinases; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Resveratrol attenuates hypoxia-induced neurotoxicity through inhibiting microglial activation.
Topics: Animals; Cell Line; Cells, Cultured; Hypoxia; Interleukin-1beta; Mice; Microglia; Mitogen-Activated Protein Kinases; Neuroprotective Agents; NF-kappa B; Nitric Oxide; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Resveratrol improved the spatial learning and memory in subclinical hypothyroidism rat induced by hemi-thyroid electrocauterization.
Topics: Animals; Antioxidants; Asymptomatic Diseases; Behavior, Animal; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Hormone Replacement Therapy; Hypothyroidism; Learning Disabilities; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neurons; Nootropic Agents; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Spatial Learning; Stilbenes; Synaptotagmin I; Thyroxine | 2015 |
High Potency of a Novel Resveratrol Derivative, 3,3',4,4'-Tetrahydroxy-trans-stilbene, against Ovarian Cancer Is Associated with an Oxidative Stress-Mediated Imbalance between DNA Damage Accumulation and Repair.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Catalase; Catechols; Cell Line, Tumor; Cell Proliferation; Deoxyguanosine; DNA Damage; DNA Glycosylases; DNA Repair; Female; Humans; Ovarian Neoplasms; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Effect of tannic acid, resveratrol and its derivatives, on oxidative damage and apoptosis in human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Carcinogens; Cells, Cultured; DNA Damage; Humans; Hydrogen Peroxide; Neutrophil Activation; Neutrophils; Oxidants; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Tannins; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2015 |
Taste Detection Thresholds of Resveratrol.
Topics: Animals; Capsules; Caseins; Chemistry, Pharmaceutical; Desiccation; Dietary Fats; Humans; Milk; Polyphenols; Resveratrol; Stilbenes; Taste; Taste Threshold | 2015 |
Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction.
Topics: Animals; Brain; Cognition Disorders; Dose-Response Relationship, Drug; Drug Delivery Systems; Grape Seed Extract; Mice; Mice, Inbred C57BL; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Sleep Deprivation; Stilbenes | 2015 |
New Insights on the Biophysical Interaction of Resveratrol with Biomembrane Models: Relevance for Its Biological Effects.
Topics: Antineoplastic Agents, Phytogenic; Cardiotonic Agents; Cholesterol; Lipid Bilayers; Liposomes; Membrane Fluidity; Molecular Structure; Neuroprotective Agents; Phosphatidylcholines; Resveratrol; Spectrophotometry; Sphingomyelins; Stilbenes | 2015 |
Effects of dietary resveratrol on excess-iron-induced bone loss via antioxidative character.
Topics: Animals; Antioxidants; Bone Density; Cell Line; Dietary Supplements; Femur; Interleukin-6; Iron Overload; Male; Mice, Inbred C57BL; Osteoporosis; Osteoprotegerin; RANK Ligand; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Synthesis, estrogenic activity, and anti-osteoporosis effects in ovariectomized rats of resveratrol oligomer derivatives.
Topics: Animals; Disease Models, Animal; Estrogen Receptor beta; Estrogens; Female; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
Enhancement of in vivo human skin penetration of resveratrol by chitosan-coated lipid microparticles.
Topics: Administration, Topical; Adult; Antioxidants; Chemistry, Pharmaceutical; Chitosan; Female; Humans; Liposomes; Male; Nanoparticles; Particle Size; Resveratrol; Skin Absorption; Solubility; Stilbenes; Surface-Active Agents; Young Adult | 2015 |
[The Radiosensitizing Effect of Resveratrol on Hopypharyngeal Carcinoma Cell Line FADU and its Effect on the Cell Cycle].
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Head and Neck Neoplasms; Humans; Hypopharyngeal Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Squamous Cell Carcinoma of Head and Neck; Stilbenes | 2015 |
Resveratrol ameliorates cisplatin-induced oxidative injury in New Zealand rabbits.
Topics: Animals; Antioxidants; Catalase; Cisplatin; Cytoprotection; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rabbits; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase | 2015 |
Mesenchymal stem cell-based HSP70 promoter-driven VEGFA induction by resveratrol alleviates elastase-induced emphysema in a mouse model.
Topics: Animals; Cell Survival; Cells, Cultured; Disease Models, Animal; Emphysema; Female; HSP70 Heat-Shock Proteins; Lung; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Nicotiana; Pancreatic Elastase; Resveratrol; Smoke; Stilbenes; Vascular Endothelial Growth Factor A | 2015 |
Resveratrol Pretreatment Ameliorates TNBS Colitis in Rats.
Topics: Animals; Antioxidants; Colitis; Female; Inflammatory Bowel Diseases; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Trinitrobenzenesulfonic Acid | 2015 |
Excited-State Proton Transfer in Resveratrol and Proposed Mechanism for Plant Resistance to Fungal Infection.
Topics: Alcohols; Cellulose; Fungi; Isomerism; Molecular Structure; Photochemical Processes; Plant Diseases; Plant Leaves; Protons; Resveratrol; Solutions; Solvents; Spectrum Analysis; Stilbenes; Viscosity; Water | 2015 |
Synthesis and pharmacological evaluation of glycosides of resveratrol, pterostilbene, and piceatannol.
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Drug Evaluation, Preclinical; Free Radical Scavengers; Glycosides; Glycosylation; Inhibitory Concentration 50; Phosphodiesterase Inhibitors; Phytolacca americana; Plant Extracts; Rats; Resveratrol; Solubility; Stilbenes | 2015 |
Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Carbamates; Chromatography, High Pressure Liquid; Esters; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Intestinal Mucosa; Kinetics; Male; Molecular Structure; Prodrugs; Rats; Rats, Wistar; Resveratrol; Solubility; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2015 |
Resveratrol inhibits oligomeric Aβ-induced microglial activation via NADPH oxidase.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents; Cell Proliferation; Cells, Cultured; Interleukin-1beta; Membrane Glycoproteins; Mice; Microglia; NADPH Oxidase 2; NADPH Oxidases; Neuroprotective Agents; Nitric Oxide; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Comprehensive evaluation of the photo-transformation routes of trans-resveratrol.
Topics: Chromatography, Liquid; Cyclization; Isomerism; Mass Spectrometry; Oxidation-Reduction; Photochemical Processes; Resveratrol; Stilbenes; Sunlight; Time Factors; Ultraviolet Rays | 2015 |
Palmitic acid increases pro-oxidant adaptor protein p66Shc expression and affects vascularization factors in angiogenic mononuclear cells: Action of resveratrol.
Topics: Antioxidants; Case-Control Studies; Cell Movement; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation; Gene Silencing; Humans; Leukocytes, Mononuclear; Male; Metabolic Syndrome; Middle Aged; Neovascularization, Physiologic; Oxidative Stress; Palmitic Acid; Resveratrol; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes | 2015 |
Targeted intracellular delivery of resveratrol to glioblastoma cells using apolipoprotein E-containing reconstituted HDL as a nanovehicle.
Topics: Antineoplastic Agents, Phytogenic; Apolipoprotein E3; Azoles; Cell Line, Tumor; Drug Delivery Systems; Endocytosis; Endosomes; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Lipoproteins, HDL; Neuroglia; Nitrobenzenes; Particle Size; Protein Structure, Tertiary; Receptors, LDL; Resveratrol; Staining and Labeling; Stilbenes | 2015 |
Dissociative Electron Attachment to Resveratrol as a Likely Pathway for Generation of the H2 Antioxidant Species Inside Mitochondria.
Topics: Antioxidants; Benzoquinones; Electron Transport; Electrons; Humans; Hydrogen; Metabolic Networks and Pathways; Mitochondria; Resveratrol; Stilbenes | 2015 |
Apoptosis like cell death in Raillietina echinobothrida induced by resveratrol.
Topics: Animals; Anthelmintics; Apoptosis; Caspases; Cestoda; DNA Fragmentation; Dose-Response Relationship, Drug; India; Mitochondrial Membranes; Phytoalexins; Plants, Medicinal; Resveratrol; Sesquiterpenes; Stilbenes | 2015 |
Analysis of the Molecular Dialogue Between Gray Mold (Botrytis cinerea) and Grapevine (Vitis vinifera) Reveals a Clear Shift in Defense Mechanisms During Berry Ripening.
Topics: Botrytis; Cell Wall; Cyclopentanes; Disease Resistance; Fruit; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Fungal; Gene Expression Regulation, Plant; Gene Ontology; Host-Pathogen Interactions; Oligonucleotide Array Sequence Analysis; Oxylipins; Phytoalexins; Plant Diseases; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Salicylates; Sesquiterpenes; Stilbenes; Virulence; Vitis | 2015 |
Regulation of Cell Cycle Regulators by SIRT1 Contributes to Resveratrol-Mediated Prevention of Pulmonary Arterial Hypertension.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Treatment Outcome; Vasodilator Agents | 2015 |
UCP2- and non-UCP2-mediated electric current in eukaryotic cells exhibits different properties.
Topics: 2,4-Dinitrophenol; Animals; Electricity; Electrodes; Electron Transport; Erythrocytes; Eukaryotic Cells; HCT116 Cells; Hepatocytes; Humans; Ion Channels; Iridoids; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Mitochondrial Proteins; Protons; Rabbits; Reactive Oxygen Species; Resveratrol; Stilbenes; Uncoupling Protein 2 | 2015 |
β-Lactoglobulin mutant Lys69Asn has attenuated IgE and increased retinol binding activity.
Topics: Antibodies, Monoclonal; Asparagine; Humans; Immunoglobulin E; Immunoglobulin G; Lactoglobulins; Lysine; Milk Hypersensitivity; Mutation; Palmitic Acid; Pichia; Protein Binding; Resveratrol; Stilbenes; Vitamin A | 2015 |
Involvement of resveratrol in crosstalk between adipokine adiponectin and hepatokine fetuin-A in vivo and in vitro.
Topics: Adipocytes; Adiponectin; alpha-2-HS-Glycoprotein; Animals; Body Weight; Coculture Techniques; Diet, High-Fat; Hepatocytes; Lipids; Liver; Male; Mice, Inbred C57BL; Obesity; Resveratrol; Stilbenes | 2015 |
Resveratrol decreases nitric oxide production by hepatocytes during inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blotting, Western; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Hepatocytes; Inflammation; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2015 |
Resveratrol potentiates the effect of dexamethasone in rat model of acute lung inflammation.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Dexamethasone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Lipopolysaccharides; Male; Pneumonia; Rats, Sprague-Dawley; Resveratrol; Smoke; Stilbenes; Tobacco Products | 2015 |
In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells.
Topics: Adult; Antioxidants; Catalase; Cells, Cultured; Dapsone; Erythrocytes; Female; Humans; Male; Methemoglobin; Methemoglobinemia; Middle Aged; Oxidation-Reduction; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Young Adult | 2015 |
Melatonin, quercetin and resveratrol attenuates oxidative hepatocellular injury in streptozotocin-induced diabetic rats.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Body Weight; Catalase; Diabetes Complications; Diabetes Mellitus, Experimental; Hepatitis; Hepatocytes; Male; Melatonin; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Novel chemical library screen identifies naturally occurring plant products that specifically disrupt glioblastoma-endothelial cell interactions.
Topics: Animals; Brain Neoplasms; Cell Communication; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Endothelial Cells; Female; Glioblastoma; Humans; Mice, Nude; Phytotherapy; Plant Extracts; Protamines; Resveratrol; Small Molecule Libraries; Spirostans; Stilbenes; Survival Analysis; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2015 |
Biocatalytic synthesis of 3,4,5,3',5'-pentahydroxy-trans-stilbene from piceatannol by two-component flavin-dependent monooxygenase HpaBC.
Topics: Bacterial Proteins; Biocatalysis; Culture Media; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Mixed Function Oxygenases; Morpholines; Polysorbates; Resveratrol; Sodium Hydroxide; Stilbenes | 2016 |
Multiple Comparisons of Glucokinase Activation Mechanisms of Five Mulberry Bioactive Ingredients in Hepatocyte.
Topics: 1-Deoxynojirimycin; Adaptor Proteins, Signal Transducing; Anthocyanins; Blood Glucose; Carrier Proteins; Glucokinase; Glucose; Glucosides; Hepatocytes; Liver; Morus; Plant Extracts; Resveratrol; Stilbenes; Up-Regulation | 2016 |
Permeation profiles of resveratrol cream delivered through porcine vaginal mucosa: Evaluation of different HPLC stationary phases.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Mucous Membrane; Resveratrol; Stilbenes; Swine; Vagina | 2015 |
Resveratrol inhibits rhinovirus replication and expression of inflammatory mediators in nasal epithelia.
Topics: Antiviral Agents; Blotting, Western; Cytokines; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; HeLa Cells; Humans; Nasal Mucosa; Organ Culture Techniques; Resveratrol; Rhinovirus; Stilbenes; Viral Load; Viral Plaque Assay; Virus Replication | 2015 |
Resveratrol ameliorates cardiac oxidative stress in diabetes through deacetylation of NFkB-p65 and histone 3.
Topics: Acetylation; Animals; Cardiomegaly; Diabetes Mellitus, Experimental; Fructosamine; Heart; Histones; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Transcription Factor RelA | 2015 |
ω-3 PUFAs and Resveratrol Differently Modulate Acute and Chronic Inflammatory Processes.
Topics: Acute Disease; Chondrocytes; Chronic Disease; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Gene Expression Regulation; Humans; Inflammation; Interleukin-10; Interleukin-6; Interleukin-8; Leukocytes; Lipopolysaccharides; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Evaluating the Effect of Expressing a Peanut Resveratrol Synthase Gene in Rice.
Topics: Acyltransferases; Arachis; Escherichia coli; Gene Expression Regulation, Plant; Oryza; Plants, Genetically Modified; Resveratrol; Seedlings; Seeds; Stilbenes | 2015 |
Resveratrol compounds inhibit human holocarboxylase synthetase and cause a lean phenotype in Drosophila melanogaster.
Topics: Adipose Tissue; Animals; Biotinylation; Carbon-Nitrogen Ligases; Drosophila melanogaster; Drosophila Proteins; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Humans; Lipase; Male; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2015 |
Resveratrol offers protection to oxidative stress induced by ferrous ascorbate in bovine spermatozoa.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Cattle; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Semen; Semen Analysis; Spermatozoa; Stilbenes; Superoxide Dismutase | 2015 |
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death.
Topics: Animals; Carbazoles; Cell Death; Cell Line, Tumor; Chromatin Immunoprecipitation; Down-Regulation; Gene Silencing; Humans; Neurons; Polychlorinated Biphenyls; Promoter Regions, Genetic; Rats; Reactive Oxygen Species; Repressor Proteins; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Investigation of the effects of soluble fibers on the absorption of resveratrol and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) in the Caco-2 cellular model of intestinal absorption.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Caco-2 Cells; Dietary Fiber; Humans; Imidazoles; Intestinal Absorption; Intestines; Resveratrol; Stilbenes | 2015 |
Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.
Topics: Alginates; Antimetabolites; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Culture Media; Drug Therapy, Combination; Epithelial Cells; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intercellular Junctions; Mesenchymal Stem Cells; Resveratrol; Stilbenes; Up-Regulation | 2015 |
Resveratrol: beneficial or not? Opposite effects of resveratrol on hypoxia-dependent PAI-1 expression in tumour and primary cells.
Topics: Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Oxygen; Plasminogen Activator Inhibitor 1; Polyphenols; Resveratrol; RNA, Messenger; Stilbenes | 2016 |
Effect of resveratrol on experimental non-alcoholic fatty liver disease depends on severity of pathology and timing of treatment.
Topics: Animals; Antioxidants; Biological Availability; Disease Models, Animal; Female; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats, Wistar; Resveratrol; Stilbenes; Triglycerides | 2016 |
Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Flow Cytometry; Humans; Lung Neoplasms; Mitochondria; Resveratrol; Stilbenes | 2015 |
Toward an understanding of the role of a catechol moiety in cancer chemoprevention: The case of copper- and o-quinone-dependent Nrf2 activation by a catechol-type resveratrol analog.
Topics: Anticarcinogenic Agents; Catechols; Copper; Hep G2 Cells; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Phosphorylation; Protein Stability; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Structure-Activity Relationship; Ubiquitination | 2015 |
Resveratrol: challenges in analyzing its biological effects.
Topics: Animals; Cell Proliferation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Resveratrol; Stilbenes | 2015 |
Resveratrol and health from a consumer perspective: perception, attitude, and adoption of a new functional ingredient.
Topics: Attitude to Health; Consumer Behavior; Cultural Characteristics; Denmark; Dietary Supplements; Health; Humans; Life Style; Resveratrol; Stilbenes; United States | 2015 |
Introduction to Resveratrol and Health: 3rd International Conference.
Topics: Health; Humans; Resveratrol; Stilbenes | 2015 |
Sustained neurological recovery induced by resveratrol is associated with angioneurogenesis rather than neuroprotection after focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic; Neurogenesis; Neurons; Oxidative Stress; Recovery of Function; Resveratrol; Rotarod Performance Test; Signal Transduction; Sirtuin 1; Stilbenes; Stroke | 2015 |
Resveratrol attenuates renal injury and fibrosis by inhibiting transforming growth factor-β pathway on matrix metalloproteinase 7.
Topics: Acute Kidney Injury; Animals; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Male; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Mice, Inbred C57BL; Resveratrol; Stilbenes; Transforming Growth Factor beta | 2016 |
Ammonia impairs glutamatergic communication in astroglial cells: protective role of resveratrol.
Topics: Ammonia; Animals; Astrocytes; Cell Line, Tumor; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glutamate-Ammonia Ligase; Glutamic Acid; Glutathione; Rats; Resveratrol; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Stilbenes | 2015 |
Resveratrol and pterostilbene epigenetically restore PTEN expression by targeting oncomiRs of the miR-17 family in prostate cancer.
Topics: 3' Untranslated Regions; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Immunohistochemistry; Lentivirus; Luciferases; Male; Mice; MicroRNAs; Prostatic Neoplasms; PTEN Phosphohydrolase; Resveratrol; RNA, Messenger; Stilbenes | 2015 |
Microemulsion Using Polyoxyethylene Sorbitan Trioleate and its Usage for Skin Delivery of Resveratrol to Protect Skin against UV-Induced Damage.
Topics: Administration, Topical; Animals; Drug Delivery Systems; Emulsions; Erythema; Guinea Pigs; Hexoses; Lipid Peroxidation; Molecular Structure; Oxidative Stress; Polyethylene Glycols; Resveratrol; Skin; Stilbenes; Ultraviolet Rays | 2015 |
The Resveratrol Tetramer r-Viniferin Induces a Cell Cycle Arrest Followed by Apoptosis in the Prostate Cancer Cell Line LNCaP.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; G1 Phase; Growth Inhibitors; Humans; Male; Polyphenols; Prostatic Neoplasms; Resveratrol; Stilbenes | 2015 |
Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Dietary Supplements; Disease Models, Animal; Lung; Male; Mangifera; Mice, Inbred ICR; Neutrophil Infiltration; Plant Extracts; Plant Leaves; Polyphenols; Pulmonary Fibrosis; Quercetin; Random Allocation; Respiratory Mucosa; Resveratrol; Stilbenes; Vitis; Xanthones | 2015 |
Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol.
Topics: Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Cell Line; Cell Survival; Enzyme Activation; Models, Molecular; NF-kappaB-Inducing Kinase; Oxadiazoles; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Effects of doxorubicin mediated by gold nanoparticles and resveratrol in two human cervical tumor cell lines.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Female; Gold; Humans; Metal Nanoparticles; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Resveratrol; Spectrum Analysis; Stilbenes; Uterine Cervical Neoplasms; X-Ray Diffraction | 2015 |
Evidence against resveratrol as a viable therapy for the rescue of defective ΔF508 CFTR.
Topics: Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; HEK293 Cells; Humans; Mutation; Resveratrol; Stilbenes | 2015 |
Modulation of human basophil activation by resveratrol.
Topics: Antioxidants; Basophils; Humans; Resveratrol; Stilbenes | 2015 |
De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae.
Topics: Acyltransferases; Arabidopsis; Chloroflexi; Ethanol; Fermentation; Glucose; Malonyl Coenzyme A; Metabolic Engineering; Metabolic Networks and Pathways; Plasmids; Protein Processing, Post-Translational; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Vitis | 2015 |
Deprotometalation-iodolysis and computed CH acidity of 1,2,3- and 1,2,4-triazoles. Application to the synthesis of resveratrol analogues.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Conformation; Resveratrol; Stilbenes; Triazoles | 2015 |
Application of monodirectional Janus patch to oromucosal delivery system.
Topics: Administration, Oral; Animals; Drug Delivery Systems; Drug Liberation; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; Male; Mice; Mouth Mucosa; Polymers; Resveratrol; Stilbenes; Transdermal Patch | 2015 |
Effect of fluoxetine and resveratrol on testicular functions and oxidative stress in a rat model of chronic mild stress-induced depression.
Topics: Animals; Antidepressive Agents, Second-Generation; Antioxidants; Body Weight; Depression; Fluoxetine; Gene Expression Regulation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Sperm Count; Sperm Motility; Stilbenes; Stress, Psychological; Swimming; Testis | 2015 |
MicroRNA-214 participates in the neuroprotective effect of Resveratrol via inhibiting α-synuclein expression in MPTP-induced Parkinson's disease mouse.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Neuroblastoma; Neuroprotective Agents; Parkinsonian Disorders; Resveratrol; RNA, Messenger; Stilbenes; Up-Regulation | 2015 |
Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors.
Topics: Chromones; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Resveratrol; Stilbenes; Structure-Activity Relationship | 2015 |
Sirt 1 activator inhibits the AGE-induced apoptosis and p53 acetylation in human vascular endothelial cells.
Topics: Acetylation; Apoptosis; Benzamides; Cardiovascular Diseases; Caspases; Cells, Cultured; Cytochromes c; Diabetes Mellitus; Endothelial Cells; Glycation End Products, Advanced; Humans; Insulin; Insulin Secretion; Naphthols; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Comparative biochemical responses and antioxidant activities of the rabbit urinary bladder to whole grapes versus resveratrol.
Topics: Animals; Antioxidants; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Fruit; Hydrogen Peroxide; Lipid Peroxidation; Male; Malondialdehyde; Mitochondria; Mucous Membrane; Muscle, Smooth; Nerve Endings; Oxidative Stress; Phytotherapy; Plant Preparations; Plants, Medicinal; Rabbits; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stilbenes; Urinary Bladder; Vitis | 2015 |
Platelet Activating Factor (PAF) biosynthesis is inhibited by phenolic compounds in U-937 cells under inflammatory conditions.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetylation; Acetyltransferases; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Diacylglycerol Cholinephosphotransferase; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-1beta; Monocytes; Osmolar Concentration; Phenylethyl Alcohol; Platelet Activating Factor; Recombinant Proteins; Resveratrol; Stilbenes | 2015 |
Resveratrol-loaded liposomes for topical treatment of the vaginal inflammation and infections.
Topics: Administration, Intravaginal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Female; Interleukin-1beta; Liposomes; Mice; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Vaginitis; Vaginosis, Bacterial | 2015 |
Resveratrol and curcumin ameliorate di-(2-ethylhexyl) phthalate induced testicular injury in rats.
Topics: Alkaline Phosphatase; Animals; Antioxidants; Curcumin; Diethylhexyl Phthalate; Gene Expression; Glutathione; Heat-Shock Proteins; Heme Oxygenase-1; Male; Malondialdehyde; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Testicular Diseases; Testis; Testosterone | 2016 |
Sirtuin 4 Regulates Lipopolysaccharide Mediated Leydig Cell Dysfunction.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Antioxidants; Apoptosis; Cell Line; Cell Survival; Gene Expression Regulation; Glutathione; JNK Mitogen-Activated Protein Kinases; Leydig Cells; Lipopolysaccharides; Male; Membrane Potential, Mitochondrial; Mitochondria; Rats; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuins; Stilbenes | 2016 |
Acidosis and Formaldehyde Secretion as a Possible Pathway of Cancer Pain and Options for Improved Cancer Pain Control.
Topics: Acidosis; Aldehyde Dehydrogenase; Dichloroacetic Acid; Formaldehyde; Glutathione; Humans; Hydrogen-Ion Concentration; Lactic Acid; Neoplasms; Pain; Pain Management; Quality of Life; Resveratrol; Sodium Bicarbonate; Stilbenes | 2015 |
Growth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain.
Topics: Biomass; Bioreactors; Gene Expression Regulation, Fungal; Metabolic Engineering; Metabolic Networks and Pathways; Resveratrol; RNA, Messenger; Saccharomyces cerevisiae; Stilbenes | 2015 |
Tackling pollution by organic farming is capable of increasing fortified foods.
Topics: Chromatography, High Pressure Liquid; Environmental Pollution; Food, Fortified; Fruit; Humans; Organic Agriculture; Resveratrol; Stilbenes; Vitis; Wine | 2016 |
Resveratrol selectively induces apoptosis in malignant cells with the JAK2V617F mutation by inhibiting the JAK2 pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cells, Cultured; Hematopoietic Stem Cells; Humans; Janus Kinase 2; Mutation; Nitriles; Pyrazoles; Pyrimidines; Resveratrol; Signal Transduction; STAT Transcription Factors; Stilbenes | 2015 |
Activation of Adenosine Monophosphate-activated Protein Kinase Suppresses Neuroinflammation and Ameliorates Bone Cancer Pain: Involvement of Inhibition on Mitogen-activated Protein Kinase.
Topics: AMP-Activated Protein Kinases; Animals; Bone Neoplasms; Cell Line, Tumor; Female; Humans; Inflammation; Mitogen-Activated Protein Kinases; Pain; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2015 |
Properties of a novel polydatin-β-d-glucosidase from Aspergillus niger SK34.002 and its application in enzymatic preparation of resveratrol.
Topics: Amino Acid Sequence; Aspergillus niger; beta-Glucosidase; Biotechnology; Biotransformation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Glucosides; Metals; Molecular Sequence Data; Resveratrol; Stilbenes; Substrate Specificity | 2016 |
Reciprocal regulation between sirtuin-1 and angiotensin-II in the substantia nigra: implications for aging and neurodegeneration.
Topics: Aging; Angiotensin II; Animals; Brain; Cell Line; Dopaminergic Neurons; Gene Expression Regulation; Homozygote; Humans; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Fluorescence; NADPH Oxidases; Neurodegenerative Diseases; Neuroglia; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Sirtuin 1; Stilbenes; Substantia Nigra | 2015 |
Preparation of resveratrol-enriched and poor allergic protein peanut sprout from ultrasound treated peanut seeds.
Topics: Arachis; Carbohydrates; Fatty Acids; Germination; Hypersensitivity; Plant Proteins; Resveratrol; Seeds; Stilbenes; Ultrasonic Waves | 2016 |
The effect of resveratrol on pharmacokinetics of aripiprazole in vivo and in vitro.
Topics: Animals; Antipsychotic Agents; Area Under Curve; Aripiprazole; Chromatography, Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2016 |
Synthesis and Biological Evaluation of Resveratrol Derivatives as Melanogenesis Inhibitors.
Topics: alpha-MSH; Animals; Biological Availability; Cell Line, Tumor; Gene Expression Regulation, Enzymologic; Melanins; Membrane Glycoproteins; Mice; Molecular Structure; Monophenol Monooxygenase; Oxidoreductases; Resveratrol; Skin Lightening Preparations; Stilbenes | 2015 |
Analysis of trans-resveratrol and trans-piceid in vegetable foods using high-performance liquid chromatography.
Topics: China; Chromatography, High Pressure Liquid; Diet; Glucosides; Humans; Resveratrol; Stilbenes; Vegetables | 2015 |
Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.
Topics: Animals; ATP Binding Cassette Transporter 1; Caco-2 Cells; Down-Regulation; Humans; Intestinal Absorption; Leucine; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Peptide Transporter 1; Rats; Rats, Wistar; Receptor, IGF Type 1; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; Symporters; Up-Regulation | 2015 |
Resveratrol inhibits canonical Wnt signaling in human MG-63 osteosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Osteosarcoma; Resveratrol; Stilbenes; Wnt Signaling Pathway | 2015 |
Resveratrol caused apoptosis in QGY-7701 cells.
Topics: Apoptosis; DNA Damage; Humans; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Development of an optimized hyaluronic acid-based lipidic nanoemulsion co-encapsulating two polyphenols for nose to brain delivery.
Topics: Administration, Intranasal; Animals; Brain; Curcumin; Emulsions; Hyaluronic Acid; Lipids; Nanoparticles; Nasal Mucosa; Neurodegenerative Diseases; Polyphenols; Rats; Resveratrol; Sheep; Stilbenes | 2016 |
Inhibitory effect of cytotoxic stilbenes related to resveratrol on the expression of the VEGF, hTERT and c-Myc genes.
Topics: Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; HEK293 Cells; HT29 Cells; Humans; MCF-7 Cells; Molecular Structure; Proto-Oncogene Proteins c-myc; Resveratrol; Stilbenes; Structure-Activity Relationship; Telomerase; Vascular Endothelial Growth Factor A | 2015 |
N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol.
Topics: Animals; Carbamates; Molecular Structure; Polyethylene Glycols; Prodrugs; Rats; Resveratrol; Stilbenes | 2015 |
The Application of Template Selectophores for the Preparation of Molecularly Imprinted Polymers.
Topics: Adsorption; Chromatography, High Pressure Liquid; Green Chemistry Technology; Molecular Imprinting; Molecular Mimicry; Molecular Structure; Polymers; Resveratrol; Stilbenes | 2015 |
Resveratrol inhibits the hydrogen dioxide-induced apoptosis via Sirt 1 activation in osteoblast cells.
Topics: Acetylation; Animals; Apoptosis; Cell Line; Gene Expression Regulation; Hydrogen Peroxide; Mice; Mitochondria; Osteoblasts; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Resveratrol inhibits oral squamous cell carcinoma through induction of apoptosis and G2/M phase cell cycle arrest.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Mouth Neoplasms; Resveratrol; Stilbenes | 2016 |
Protecting the BBB endothelium against cigarette smoke-induced oxidative stress using popular antioxidants: Are they really beneficial?
Topics: Antioxidants; Blood-Brain Barrier; Cell Line, Transformed; Cell Survival; Cullin Proteins; Cytokines; Endothelium; Enzyme-Linked Immunosorbent Assay; Glutathione; Humans; L-Lactate Dehydrogenase; Melatonin; Oxidative Stress; Plant Extracts; Platelet Endothelial Cell Adhesion Molecule-1; Resveratrol; Stilbenes; Tobacco Products; Ubiquinone; Up-Regulation; Vascular Endothelial Growth Factor A | 2015 |
Effect of Resveratrol on Leptin and Sirtuin 2 Expression in the Kidneys in Streptozotocin-induced Diabetic Rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Female; Immunohistochemistry; Kidney; Leptin; Rats; Rats, Wistar; Resveratrol; Sirtuin 2; Stilbenes | 2015 |
Genome Expression Profiling-Based Identification and Administration Efficacy of Host-Directed Antimicrobial Drugs against Respiratory Infection by Nontypeable Haemophilus influenzae.
Topics: Animals; Anti-Bacterial Agents; Cell Line, Tumor; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Therapy, Combination; Enzyme Activation; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Genome, Human; Haemophilus Infections; Haemophilus influenzae; Host-Pathogen Interactions; Humans; Lung; Mice; Phosphodiesterase 4 Inhibitors; Respiratory Mucosa; Resveratrol; Rolipram; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Deep sequencing analysis of transcriptomes in Aspergillus flavus in response to resveratrol.
Topics: Aflatoxins; Antifungal Agents; Aspergillus flavus; Gene Expression Profiling; Gene Expression Regulation, Fungal; High-Throughput Nucleotide Sequencing; Mycelium; Resveratrol; Spores, Fungal; Stilbenes | 2015 |
Protective effect of resveratrol against neuronal damage following transient global cerebral ischemia in mice.
Topics: Animals; Brain Ischemia; Male; Mice; Mice, Inbred C57BL; Neurons; Resveratrol; Stilbenes | 2016 |
Resveratrol prevents renal lipotoxicity in high-fat diet-treated mouse model through regulating PPAR-α pathway.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; PPAR alpha; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Pomegranate Seed Oil Exerts Synergistic Effects with trans-Resveratrol in a Self-nanoemulsifying Drug Delivery System.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Survival; Drug Delivery Systems; Drug Synergism; Edema; Gastric Juice; Humans; Intestinal Secretions; Lythraceae; MCF-7 Cells; Mice; Plant Oils; Resveratrol; Seeds; Solubility; Stilbenes; Water | 2015 |
Topical trans-resveratrol ameliorates steroid-induced anterior and posterior segment changes in rats.
Topics: Administration, Topical; Animals; Antioxidants; Aqueous Humor; Cell Count; Disease Models, Animal; Female; Glucocorticoids; Intraocular Pressure; Male; Matrix Metalloproteinase 2; Ocular Hypertension; Ophthalmic Solutions; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Retina; Retinal Ganglion Cells; Stilbenes; Tonometry, Ocular; Trabecular Meshwork | 2016 |
Resveratrol attenuates norepinephrine-induced ovarian cancer invasiveness through downregulating hTERT expression.
Topics: Adrenergic beta-Antagonists; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasm Invasiveness; Norepinephrine; Ovarian Neoplasms; Phosphorylation; Resveratrol; Signal Transduction; Snail Family Transcription Factors; src-Family Kinases; Stilbenes; Telomerase; Transfection | 2016 |
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Proliferation; Cell Survival; Cyclin D1; Female; Gene Expression; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Molecular Chaperones; Phosphorylation; Protein Inhibitors of Activated STAT; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Proto-Oncogene Proteins c-myc; Resveratrol; RNA, Neoplasm; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Survivin; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A | 2015 |
In Vitro Safety/Protection Assessment of Resveratrol and Pterostilbene in a Human Hepatoma Cell Line (HepG2).
Topics: Apoptosis; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Humans; Liver Neoplasms; Protective Agents; Resveratrol; Stilbenes | 2015 |
Profiling of bioactive compounds in cultivars of Runner and Valencia peanut market-types using liquid chromatography/APCI mass spectrometry.
Topics: Arachis; Chromatography, Liquid; Mass Spectrometry; Quercetin; Resveratrol; Stilbenes | 2012 |
Time--and Concentration--Dependent Effects of Resveratrol on miR 15a and miR16-1 Expression and Apoptosis in the CCRF-CEM Acute Lymphoblastic Leukemia Cell Line.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression; Humans; MicroRNAs; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes; Time Factors; Up-Regulation | 2015 |
Therapeutic Effect of Resveratrol on Oxidative Stress in Graves' Orbitopathy Orbital Fibroblasts.
Topics: Adipocytes; Adipogenesis; Angiogenesis Inhibitors; Antioxidants; Cell Proliferation; Cells, Cultured; Fibroblasts; Graves Ophthalmopathy; Humans; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol Stimulates Hydrogen Sulfide (H2 S) Formation to Relax Murine Corpus Cavernosum.
Topics: Animals; Arginine; Cysteine; Hydrogen Sulfide; Male; Mice; Muscle Relaxation; Nitric Oxide; Penile Erection; Penis; Resveratrol; Signal Transduction; Stilbenes; Vasodilator Agents | 2015 |
Effect of resveratrol and lipoic acid on sirtuin-regulated expression of metabolic genes in bovine liver and muscle slice cultures.
Topics: Animals; Antioxidants; Blotting, Western; Cattle; Forkhead Transcription Factors; Gene Expression Regulation; Gluconeogenesis; Glucose; Lipid Metabolism; Liver; Male; Muscle, Skeletal; PPAR gamma; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Sirtuins; Stilbenes; Thioctic Acid; Tissue Culture Techniques | 2015 |
Food Polyphenols Fail to Cause a Biologically Relevant Reduction of COX-2 Activity.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Celecoxib; Cell Line, Tumor; Cells, Cultured; Cyclooxygenase 2; Enzyme Activation; Genistein; Humans; Indomethacin; Lipopolysaccharides; Male; Mice, Inbred C57BL; Monocytes; Polyphenols; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes | 2015 |
Treatment of SMB-S15 Cells with Resveratrol Efficiently Removes the PrP(Sc) Accumulation In Vitro and Prion Infectivity In Vivo.
Topics: Animals; Brain; Cell Line; Injections, Intraventricular; Mice; Prion Diseases; PrPSc Proteins; Resveratrol; Stilbenes; Sus scrofa | 2016 |
ERK5/HDAC5-mediated, resveratrol-, and pterostilbene-induced expression of MnSOD in human endothelial cells.
Topics: AMP-Activated Protein Kinases; Animals; Base Sequence; Gene Expression Regulation, Enzymologic; Histone Deacetylases; Human Umbilical Vein Endothelial Cells; Humans; Kruppel-Like Transcription Factors; Mitochondria; Mitogen-Activated Protein Kinase 12; Molecular Sequence Data; Oxidative Stress; Phosphorylation; Rats; Resveratrol; Stilbenes; Superoxide Dismutase | 2016 |
Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase.
Topics: Animals; Benzofurans; Biological Products; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Hepacivirus; Humans; Phenols; Protein Binding; Rats; Resveratrol; RNA Helicases; Sofosbuvir; Stilbenes; Tissue Distribution; Viral Nonstructural Proteins; Virus Replication | 2016 |
Resveratrol exerts a biphasic effect on apolipoprotein M.
Topics: Animals; Apolipoproteins; Apolipoproteins M; Dose-Response Relationship, Drug; Extracellular Space; Hep G2 Cells; Hepatocytes; Humans; Lipocalins; Lysophospholipids; Mice; Primary Cell Culture; Receptors, LDL; Resveratrol; RNA, Small Interfering; Sirtuin 1; Sphingosine; Stilbenes | 2016 |
Resveratrol stimulates cyclic AMP response element mediated gene transcription.
Topics: Activating Transcription Factor 2; Anticarcinogenic Agents; Cells, Cultured; Curcumin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Flavanones; Gene Expression Regulation; HEK293 Cells; Hep G2 Cells; Humans; Neural Stem Cells; Quercetin; Response Elements; Resveratrol; Stilbenes; Transcriptional Activation; Up-Regulation | 2016 |
Resveratrol Inhibits Hypoxia-Induced Vascular Endothelial Growth Factor Expression and Pathological Neovascularization.
Topics: Adult; Animals; Cell Survival; Choroidal Neovascularization; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proteasome Endopeptidase Complex; Proto-Oncogene Proteins c-akt; Resveratrol; Retinal Pigment Epithelium; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Ubiquitin; Vascular Endothelial Growth Factor A | 2015 |
Vitis thunbergii var. taiwaniana Extracts and Purified Compounds Ameliorate Obesity in High-Fat Diet-Induced Obese Mice.
Topics: Animals; Cholesterol; Diet, High-Fat; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Phytotherapy; Plant Extracts; Plant Leaves; Plant Stems; Resveratrol; Stilbenes; Taiwan; Triglycerides; Vitis | 2015 |
Kinetic characterization of oxyresveratrol as a tyrosinase substrate.
Topics: Fungal Proteins; Hydrogen Peroxide; Hydroxylation; Kinetics; Levodopa; Monophenol Monooxygenase; Plant Extracts; Resveratrol; Stilbenes; Substrate Specificity; Tyrosine | 2015 |
Acute Treatment of Resveratrol Alleviates Doxorubicin-Induced Myotoxicity in Aged Skeletal Muscle Through SIRT1-Dependent Mechanisms.
Topics: Age Factors; Animals; Apoptosis; Cardiotoxicity; Caspase 3; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Male; Mice; Muscle, Skeletal; Oxidative Stress; Proteasome Endopeptidase Complex; Pyruvate Dehydrogenase Complex; Random Allocation; Resveratrol; Signal Transduction; Sirtuin 1; Staining and Labeling; Stilbenes | 2016 |
miR-27b overexpression improves mitochondrial function in a Sirt1-dependent manner.
Topics: Animals; Antioxidants; Blood Glucose; Cell Line; Drug Evaluation, Preclinical; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Male; Mice, Inbred C57BL; MicroRNAs; Mitochondria, Muscle; Muscle, Skeletal; Resveratrol; RNA Interference; Sirtuin 1; Stilbenes; Weight Gain | 2015 |
Resveratrol decreases the insoluble Aβ1-42 level in hippocampus and protects the integrity of the blood-brain barrier in AD rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood-Brain Barrier; Claudin-5; Disease Models, Animal; Female; Galactose; Glycation End Products, Advanced; Hippocampus; Matrix Metalloproteinase 9; Ovariectomy; Peptide Fragments; Rats; Rats, Wistar; Resveratrol; Stilbenes; Transcription Factor RelA | 2015 |
Concentration-dependent effects of resveratrol and metabolites on the redox status of human erythrocytes in single-dose studies.
Topics: Erythrocytes; Humans; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
[Effects of resveratrol on hippocampal astrocytes and expression of TNF-α in Alzheimer's disease model rate].
Topics: Alzheimer Disease; Animals; Astrocytes; Disease Models, Animal; Estradiol; Female; Galactose; Glial Fibrillary Acidic Protein; Hippocampus; Humans; Ovariectomy; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Inhibition of topoisomerase II by phase II metabolites of resveratrol in human colon cancer cells.
Topics: Apoptosis; Caco-2 Cells; Cell-Free System; Colonic Neoplasms; Comet Assay; Drug Screening Assays, Antitumor; Glucuronides; HT29 Cells; Humans; Resveratrol; Stilbenes; Topoisomerase II Inhibitors | 2015 |
Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo.
Topics: Animals; Biomarkers; Blood Glucose; Disease Models, Animal; Dyslipidemias; Emulsions; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; I-kappa B Kinase; I-kappa B Proteins; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Muscle, Skeletal; NF-KappaB Inhibitor alpha; Phospholipids; Phosphorylation; Rats, Wistar; Resveratrol; Serine; Soybean Oil; Stilbenes; Time Factors; Up-Regulation | 2015 |
Resveratrol Reverses the Synaptic Plasticity Deficits in a Chronic Cerebral Hypoperfusion Rat Model.
Topics: Animals; Carotid Stenosis; Cerebrovascular Circulation; Chronic Disease; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dementia, Vascular; Dendritic Spines; Dentate Gyrus; Enzyme Activation; Hypoxia-Ischemia, Brain; Learning Disabilities; Long-Term Potentiation; Male; Maze Learning; Memory Disorders; Nerve Tissue Proteins; Neuroprotective Agents; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Resveratrol induces ordered domains formation in biomembranes: Implication for its pleiotropic action.
Topics: Animals; Chickens; Cholesterol; Cyclic N-Oxides; Diphenylhexatriene; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Lipid Bilayers; Liposomes; Membrane Microdomains; Octoxynol; Phosphatidylcholines; Resveratrol; Sphingomyelins; Stilbenes; Thermodynamics | 2016 |
Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation.
Topics: Adult; beta Catenin; Cellular Senescence; Humans; Mesenchymal Stem Cells; Resveratrol; Stilbenes | 2015 |
Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERα status.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Drug Interactions; Estrogen Receptor alpha; Female; Humans; Integrin alphaVbeta3; MCF-7 Cells; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Scavenging of Toxic Acrolein by Resveratrol and Hesperetin and Identification of Adducts.
Topics: Acrolein; Antioxidants; Hesperidin; Hydrogen-Ion Concentration; Molecular Structure; Resveratrol; Stilbenes | 2015 |
Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Aquaporin 4; Brain; Brain Ischemia; Male; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2015 |
Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Epigenesis, Genetic; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histones; Humans; Receptor, ErbB-2; Resveratrol; Sirtuin 1; Stilbenes; Telomerase; Triple Negative Breast Neoplasms | 2015 |
Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Caspases; Cell Proliferation; Cell Survival; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Humans; K562 Cells; Leucine; Leukemia, Erythroblastic, Acute; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2016 |
Amino Acid Carbamates As Prodrugs Of Resveratrol.
Topics: Administration, Oral; Amino Acids; Animals; Carbamates; Drug Design; Male; Metabolic Clearance Rate; Prodrugs; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2015 |
Resveratrol pretreatment protects rat hearts from ischemia/reperfusion injury partly via a NALP3 inflammasome pathway.
Topics: Animals; Antioxidants; Blotting, Western; Carrier Proteins; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Heart; Inflammasomes; Male; Microscopy, Electron, Transmission; Myocardial Reperfusion Injury; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes | 2015 |
Anti-inflammatory Effects of Resveratrol on Hypoxia/Reoxygenation-Induced Alveolar Epithelial Cell Dysfunction.
Topics: Anti-Inflammatory Agents; Cell Line; Epithelial Cells; Humans; Hypoxia; Interleukin-1beta; Interleukin-6; Lung Injury; Oxygen; Pulmonary Alveoli; Resveratrol; Stilbenes | 2015 |
Effects of Resveratrol on Receptor for Advanced Glycation End Products (RAGE) Expression and Oxidative Stress in the Liver of Rats with Type 2 Diabetes.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Resveratrol; Stilbenes | 2016 |
Effect of resveratrol on metabolic and cardiovascular function in male and female adult offspring exposed to prenatal hypoxia and a high-fat diet.
Topics: Animals; Cardiotonic Agents; Cardiovascular Diseases; Diet, High-Fat; Female; Fetal Hypoxia; Heart; Male; Myocardial Contraction; Myocardium; Pregnancy; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxides; Ventricular Function | 2016 |
Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites.
Topics: Amyloid; Binding Sites; Humans; Molecular Probes; Polyphenols; Prealbumin; Protein Denaturation; Resveratrol; Stilbenes; Urea | 2015 |
Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.
Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; DNA Adducts; Drug Resistance, Neoplasm; Gene Expression Regulation; Histones; Humans; Hydrogels; Microscopy, Confocal; Prodrugs; Resveratrol; Stilbenes; Thiazoles | 2015 |
Plant stilbenes induce endoplasmic reticulum stress and their anti-cancer activity can be enhanced by inhibitors of autophagy.
Topics: Antimalarials; Antineoplastic Agents; Antioxidants; Autophagy; Blotting, Western; Cell Proliferation; Chloroquine; Drug Synergism; Drug Therapy, Combination; Endoplasmic Reticulum Stress; Fibrosarcoma; High-Throughput Screening Assays; Humans; Plants; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Small Molecule Libraries; Stilbenes; Tumor Cells, Cultured | 2015 |
Antibacterial nanocarriers of resveratrol with gold and silver nanoparticles.
Topics: Anti-Bacterial Agents; Bacteria; Gold; Metal Nanoparticles; Microscopy, Atomic Force; Particle Size; Resveratrol; Silver; Stilbenes | 2016 |
Enhancing delivery and cytotoxicity of resveratrol through a dual nanoencapsulation approach.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Structure-Activity Relationship; Surface Properties | 2016 |
Resveratrol inhibits collagen-induced platelet stimulation through suppressing NADPH oxidase and oxidative inactivation of SH2 domain-containing protein tyrosine phosphatase-2.
Topics: Antioxidants; Blood Platelets; Collagen; Enzyme Activation; Flow Cytometry; Humans; Immunoblotting; Immunoprecipitation; NADPH Oxidases; Platelet Activation; Platelet Aggregation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Use of In Vitro and Predictive In Silico Models to Study the Inhibition of Cytochrome P4503A by Stilbenes.
Topics: Animals; Caco-2 Cells; Cell Survival; Computational Biology; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Humans; In Vitro Techniques; Male; Microsomes, Liver; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Testosterone | 2015 |
Resveratrol abrogates lipopolysaccharide-induced depressive-like behavior, neuroinflammatory response, and CREB/BDNF signaling in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cell Nucleus; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cytokines; Depression; Food Preferences; Hippocampus; Inflammation; Lipopolysaccharides; Male; Mice; Motor Activity; NF-kappa B; Prefrontal Cortex; Resveratrol; Signal Transduction; Stilbenes; Sucrose | 2015 |
Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration.
Topics: Antioxidants; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblasts; Fibrosis; Humans; Hydrogen Peroxide; Light; Phototherapy; Resveratrol; Skin; Stilbenes | 2015 |
Root Transcriptome Analysis of Wild Peanut Reveals Candidate Genes for Nematode Resistance.
Topics: Animals; Arachis; Cyclopentanes; Disease Resistance; Gene Expression Profiling; Genes, Plant; Lipocalins; Oxylipins; Plant Diseases; Plant Roots; Resveratrol; Stilbenes; Tylenchoidea | 2015 |
Long-Term Dietary Fructose Causes Gender-Different Metabolic and Vascular Dysfunction in Rats: Modulatory Effects of Resveratrol.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Body Weight; Diet; Female; Fructose; Insulin; Insulin Receptor Substrate Proteins; Lipoproteins, VLDL; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Sex Factors; Sirtuin 1; Stilbenes; Triglycerides | 2015 |
Association of habitual dietary resveratrol exposure with the development of frailty in older age: the Invecchiare in Chianti study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cohort Studies; Diet; Elder Nutritional Physiological Phenomena; Fatigue; Feeding Behavior; Female; Frail Elderly; Humans; Italy; Longitudinal Studies; Male; Muscle Weakness; Prospective Studies; Registries; Resveratrol; Risk Factors; Stilbenes | 2015 |
Resveratrol prevents alveolar bone loss in an experimental rat model of periodontitis.
Topics: Adult; Alveolar Bone Loss; Animals; Disease Models, Animal; Extracellular Matrix Proteins; Humans; Lipopolysaccharides; Male; Periodontitis; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol ameliorates hepatic steatosis and inflammation in methionine/choline-deficient diet-induced steatohepatitis through regulating autophagy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Choline Deficiency; Cytokines; Drug Evaluation, Preclinical; Gene Expression; Male; Methionine; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Resveratrol; Stilbenes | 2015 |
Resveratrol sensitizes glioblastoma-initiating cells to temozolomide by inducing cell apoptosis and promoting differentiation.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neoplastic Stem Cells; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; Temozolomide; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Resveratrol alleviates diabetes-induced testicular dysfunction by inhibiting oxidative stress and c-Jun N-terminal kinase signaling in rats.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Hyperglycemia; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Streptozocin; Superoxide Dismutase; Testicular Diseases; Transcription Factor AP-1 | 2015 |
Resveratrol induces human keratinocyte damage via the activation of class III histone deacetylase, Sirt1.
Topics: Apoptosis; Cell Line; Gene Expression Regulation; Humans; Keratinocytes; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA-Binding Proteins; Sirtuin 1; Stilbenes | 2016 |
Utilization of Dioxygen by Carotenoid Cleavage Oxygenases.
Topics: Animals; Bacterial Proteins; Carotenoids; Cattle; Dioxygenases; Intramolecular Oxidoreductases; Oxygen; Resveratrol; Stilbenes; Synechocystis | 2015 |
Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Line, Transformed; Curcumin; Dogs; Glucuronides; Glucuronosyltransferase; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Male; Membrane Transport Proteins; Metabolic Detoxication, Phase II; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Resveratrol; Stilbenes; UDP-Glucuronosyltransferase 1A9 | 2016 |
Resveratrol could reverse the expression of SIRT1 and MMP-1 in vitro.
Topics: Adult; Aged; Aggrecans; Cells, Cultured; Collagen Type II; Female; Gene Expression Regulation; Humans; Immunohistochemistry; In Vitro Techniques; Male; Matrix Metalloproteinase 1; Middle Aged; Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Young Adult | 2015 |
The protective effect of resveratrol against dentin bonding agents-induced cytotoxicity.
Topics: Animals; Cell Culture Techniques; Cell Survival; Cytotoxins; Dental Bonding; Dentin-Bonding Agents; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Glutaral; Methacrylates; Mice; Oxidative Stress; Polymethacrylic Acids; Reactive Oxygen Species; Resin Cements; Resveratrol; Stilbenes | 2015 |
Neuroprotection of Neuro2a cells and the cytokine suppressive and anti-inflammatory mode of action of resveratrol in activated RAW264.7 macrophages and C8-B4 microglia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Coculture Techniques; Cytokines; Macrophages; Mice; Microglia; Neuroprotection; Resveratrol; Stilbenes | 2016 |
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Topics: Animals; Benzofurans; Cytokines; Diet, High-Fat; Hep G2 Cells; HMGB1 Protein; Humans; Liver; Male; Non-alcoholic Fatty Liver Disease; Palmitic Acid; Protective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Up-Regulation | 2015 |
Function of sustained released resveratrol on IL-1β-induced hBMSC MMP13 secretion inhibition and chondrogenic differentiation promotion.
Topics: Antioxidants; Arthritis; Cell Differentiation; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes; Coculture Techniques; Drug Carriers; Drug Delivery Systems; Humans; Inflammation; Interleukin-1beta; Lactic Acid; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Mesenchymal Stem Cells; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; SOX9 Transcription Factor; Stilbenes | 2016 |
Enhanced extracellular production of trans-resveratrol in Vitis vinifera suspension cultured cells by using cyclodextrins and coronatine.
Topics: Amino Acids; Cell Proliferation; Cells, Cultured; Cyclodextrins; Extracellular Space; Gene Expression Regulation, Plant; Indenes; Intracellular Space; Resveratrol; Stilbenes; Suspensions; Vitis | 2015 |
Resveratrol attenuates the progress of liver fibrosis via the Akt/nuclear factor-κB pathways.
Topics: Actins; Animals; Biomarkers; Cell Line; Disease Models, Animal; Disease Progression; Enzyme Activation; Humans; Liver Cirrhosis; Male; Mice, Inbred C57BL; NF-kappa B; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; Stomach Neoplasms | 2016 |
Potential Compounds for Oral Cancer Treatment: Resveratrol, Nimbolide, Lovastatin, Bortezomib, Vorinostat, Berberine, Pterostilbene, Deguelin, Andrographolide, and Colchicine.
Topics: Administration, Oral; Algorithms; Antineoplastic Agents; Berberine; Bortezomib; Colchicine; Databases, Pharmaceutical; Databases, Protein; Diterpenes; Humans; Hydroxamic Acids; Limonins; Lovastatin; Models, Statistical; Mouth Neoplasms; Predictive Value of Tests; Resveratrol; Rotenone; Stilbenes; Support Vector Machine; Vorinostat | 2015 |
Resveratrol Induces Glioma Cell Apoptosis through Activation of Tristetraprolin.
Topics: 3' Untranslated Regions; Apoptosis; AU Rich Elements; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Fibroblasts; Gene Expression Regulation; Glioma; Humans; Receptors, Urokinase Plasminogen Activator; Resveratrol; RNA Stability; RNA, Messenger; Stilbenes; Tristetraprolin; Up-Regulation; Urokinase-Type Plasminogen Activator | 2015 |
Resveratrol-Related Polymethoxystilbene Glycosides: Synthesis, Antiproliferative Activity, and Glycosidase Inhibition.
Topics: alpha-Glucosidases; Antineoplastic Agents; Caco-2 Cells; Cell Proliferation; Fluorouracil; Glycoside Hydrolase Inhibitors; Glycosides; Humans; Molecular Structure; Resveratrol; Stereoisomerism; Stilbenes | 2015 |
Resveratrol relieves gestational diabetes mellitus in mice through activating AMPK.
Topics: Adenylate Kinase; Animals; Blood Glucose; Diabetes, Gestational; Female; Insulin Resistance; Mice; Pregnancy; Resveratrol; Signal Transduction; Stilbenes; Treatment Outcome | 2015 |
Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency.
Topics: Action Potentials; Berberine; Caveolin 1; Cell Membrane; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Mutation; Phenylalanine; Potassium Channel Blockers; Resveratrol; RNA Interference; Stilbenes; Terfenadine; Transfection; Tyrosine | 2015 |
Pretreatment with Resveratrol Prevents Neuronal Injury and Cognitive Deficits Induced by Perinatal Hypoxia-Ischemia in Rats.
Topics: Animals; Animals, Newborn; Astrocytes; Behavior, Animal; Brain; Brain Injuries; Cognition Disorders; Disease Models, Animal; Female; Hypoxia-Ischemia, Brain; Male; Membrane Potential, Mitochondrial; Mitochondria; Myelin Basic Protein; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol inhibits mucus overproduction and MUC5AC expression in a murine model of asthma.
Topics: Animals; Asthma; Cell Line; Disease Models, Animal; Epithelial Cells; Female; Gene Expression Regulation; Humans; Lung; Mice, Inbred BALB C; Mucin 5AC; Mucus; Pneumonia; Resveratrol; Stilbenes | 2016 |
Resveratrol induces cell death and inhibits human herpesvirus 8 replication in primary effusion lymphoma cells.
Topics: Apoptosis; Autophagy; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Herpesvirus 8, Human; Humans; Lymphoma, Primary Effusion; Reactive Oxygen Species; Resveratrol; Stilbenes; Virus Replication | 2015 |
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy.
Topics: Acetylation; Animals; Biomarkers; Cell Movement; Cell Proliferation; Disease Models, Animal; Disease Progression; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibronectins; Rabbits; Resveratrol; Retinal Pigment Epithelium; Sirtuin 1; Smad4 Protein; Stilbenes; Transforming Growth Factor beta2; Vitreoretinopathy, Proliferative | 2015 |
Influence of resveratrol release on the tissue response to mechanically adaptive cortical implants.
Topics: Animals; Blood-Brain Barrier; Cerebral Cortex; Drug Delivery Systems; Inflammation; Macrophages; Male; Microelectrodes; Microglia; Nanocomposites; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
BMP9/p38 MAPK is essential for the antiproliferative effect of resveratrol on human colon cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Flow Cytometry; Growth Differentiation Factor 2; Growth Differentiation Factors; Humans; Immunohistochemistry; Mice; Mice, Nude; p38 Mitogen-Activated Protein Kinases; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
Chemopreventive effect of resveratrol and apocynin on pancreatic carcinogenesis via modulation of nuclear phosphorylated GSK3β and ERK1/2.
Topics: Acetophenones; Adenocarcinoma; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Carcinogenesis; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chemoprevention; Cricetinae; Disease Models, Animal; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; MAP Kinase Signaling System; Mesocricetus; Pancreatic Neoplasms; Phosphorylation; Resveratrol; Stilbenes | 2015 |
3,5,4'-Tri-O-acetylresveratrol decreases seawater inhalation-induced acute lung injury by interfering with the NF-κB and i-NOS pathways.
Topics: Acetylation; Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Interleukin-1beta; Lung; Male; NF-kappa B; Nitric Oxide Synthase Type II; Rats, Sprague-Dawley; Resveratrol; Seawater; Signal Transduction; Stilbenes | 2016 |
Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in vitro.
Topics: Antioxidants; Cell Line; Cell Survival; Contrast Media; DNA Fragmentation; Epithelial Cells; Humans; Iothalamic Acid; Kidney Tubules, Proximal; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
SIRT1 and FOXO Mediate Contractile Differentiation of Vascular Smooth Muscle Cells under Cyclic Stretch.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium-Binding Proteins; Calponins; Cell Cycle Proteins; Cell Differentiation; Cells, Cultured; Forkhead Box Protein O3; Forkhead Transcription Factors; Mice; Mice, Knockout; Microfilament Proteins; Muscle Contraction; Muscle Proteins; Myocytes, Smooth Muscle; Rats; Resveratrol; RNA Interference; RNA, Small Interfering; Sirtuin 1; Stilbenes; Stress, Mechanical; Up-Regulation | 2015 |
The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antioxidants; Aspartic Acid Endopeptidases; Caspase 3; Cell Death; Cell Line, Tumor; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Gene Expression Regulation; Glycation End Products, Advanced; Heat-Shock Proteins; Humans; Neurons; Neuroprotective Agents; Plaque, Amyloid; Presenilin-1; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation | 2015 |
Mitochondrial Dysfunction Launches Dexamethasone-Induced Skeletal Muscle Atrophy via AMPK/FOXO3 Signaling.
Topics: Animals; Cell Differentiation; Cell Line; Dexamethasone; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Real-time quantification of oxidative stress and the protective effect of nitroxide antioxidants.
Topics: Animals; Antioxidants; Cell Line; Extracellular Space; Female; Mitochondria; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Photoreceptor Cells, Vertebrate; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Retinal Vessels; Stilbenes | 2016 |
Effect of resveratrol or ascorbic acid on the stability of α-tocopherol in O/W emulsions stabilized by whey protein isolate: Simultaneous encapsulation of the vitamin and the protective antioxidant.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Drug Stability; Emulsions; Food Handling; Hydrophobic and Hydrophilic Interactions; Resveratrol; Stilbenes; Vitamins; Water; Whey Proteins | 2016 |
ε-Viniferin, a resveratrol dimer, prevents diet-induced obesity in mice.
Topics: 3T3 Cells; Adipogenesis; Animals; Anti-Obesity Agents; Benzofurans; Diet, High-Fat; Dimerization; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Obesity; Resveratrol; Stilbenes; Treatment Outcome | 2015 |
α-Viniferin and resveratrol induced alteration in the activities of some energy metabolism related enzymes in the cestode parasite Raillietina echinobothrida.
Topics: Animals; Anthelmintics; Benzofurans; Cestoda; Energy Metabolism; Enzyme Inhibitors; L-Lactate Dehydrogenase; Malate Dehydrogenase; Phosphoenolpyruvate Carboxykinase (ATP); Praziquantel; Resveratrol; Stilbenes | 2016 |
Systemic administration of resveratrol suppress the nociceptive neuronal activity of spinal trigeminal nucleus caudalis in rats.
Topics: Action Potentials; Administration, Intravenous; Analgesics; Animals; Dose-Response Relationship, Drug; Face; Male; Microelectrodes; Neurons; Nociception; Physical Stimulation; Rats, Wistar; Resveratrol; Stilbenes; Touch; Trigeminal Caudal Nucleus | 2016 |
Resveratrol Protects against Helicobacter pylori-Associated Gastritis by Combating Oxidative Stress.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Disease Models, Animal; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Heme Oxygenase-1; Interleukin-8; Lipid Peroxides; Male; Mice; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Phosphorylation; Resveratrol; Stilbenes | 2015 |
Resveratrol as a Bioenhancer to Improve Anti-Inflammatory Activities of Apigenin.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Carrageenan; Cyclooxygenase 2; Dinoprostone; Drug Synergism; Edema; Glucuronosyltransferase; Hep G2 Cells; Humans; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Evaluation of brain SERT occupancy by resveratrol against MDMA-induced neurobiological and behavioral changes in rats: A 4-[¹⁸F]-ADAM/small-animal PET study.
Topics: Animals; Benzylamines; Brain; Brain Mapping; Corticosterone; Depressive Disorder; Dose-Response Relationship, Drug; Fluorine Radioisotopes; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Positron-Emission Tomography; Radiopharmaceuticals; Random Allocation; Rats, Sprague-Dawley; Resveratrol; RNA-Binding Proteins; Serotonin Agents; Stilbenes | 2016 |
Resveratrol Regulates Activated Hepatic Stellate Cells by Modulating NF-κB and the PI3K/Akt Signaling Pathway.
Topics: Actins; Animals; Cell Line; Cell Survival; Collagen; Hepatic Stellate Cells; Lipopolysaccharides; Liver; Liver Cirrhosis; Myeloid Differentiation Factor 88; NF-kappa B; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phosphorylation; Phytotherapy; Plant Extracts; Protein Serine-Threonine Kinases; Rats; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4 | 2016 |
Development and validation of a simple high performance thin layer chromatography method combined with direct 1,1-diphenyl-2-picrylhydrazyl assay to quantify free radical scavenging activity in wine.
Topics: Antioxidants; Biphenyl Compounds; Caffeic Acids; Chromatography, Thin Layer; Free Radical Scavengers; Gallic Acid; Picrates; Polyphenols; Reproducibility of Results; Resveratrol; Rutin; Stilbenes; Wine | 2016 |
Stability indicating simplified HPLC method for simultaneous analysis of resveratrol and quercetin in nanoparticles and human plasma.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Limit of Detection; Nanoparticles; Quercetin; Resveratrol; Stilbenes | 2016 |
Resveratrol inhibits ovarian tumor growth in an in vivo mouse model.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Carcinoma, Ovarian Epithelial; Cell Proliferation; Cell Survival; Cisplatin; Female; Glucose; Glycolysis; Humans; In Vitro Techniques; Mice; Neoplasm Transplantation; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Positron-Emission Tomography; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
Effects of resveratrol on methotrexate-induced intestinal injury.
Topics: Animals; Antimetabolites, Antineoplastic; Catalase; In Situ Nick-End Labeling; Intestine, Small; Male; Methotrexate; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2015 |
Resveratrol Suppresses Cytokine Production Linked to FcεRI-MAPK Activation in IgE-Antigen Complex-Exposed Basophilic Mast Cells and Mice.
Topics: Animals; Cells, Cultured; Cytokines; Dinitrophenols; Disease Models, Animal; Dose-Response Relationship, Drug; Hypersensitivity; Immunoglobulin E; Inflammation; Male; MAP Kinase Signaling System; Mast Cells; Mice; Mice, Inbred BALB C; Molecular Targeted Therapy; Phosphorylation; Phytotherapy; Receptors, IgE; Resveratrol; Serum Albumin; Stilbenes; Th2 Cells | 2015 |
The Differential Effects of Resveratrol and trans-ε-Viniferin on the GABA-Induced Current in GABAA Receptor Subtypes Expressed in Xenopus Laevis Oocytes.
Topics: Animals; Benzofurans; Binding Sites; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Humans; Imidazoles; Inhibitory Concentration 50; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Resveratrol; Stilbenes; Xenopus laevis | 2015 |
Attenuation of Oxidative Stress in HEK 293 Cells by the TCM Constituents Schisanhenol, Baicalein, Resveratrol or Crocetin and Two Defined Mixtures.
Topics: Antioxidants; Carotenoids; Cyclooctanes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; HEK293 Cells; Humans; Medicine, Chinese Traditional; Oxidation-Reduction; Oxidative Stress; Polycyclic Compounds; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; tert-Butylhydroperoxide; Vitamin A | 2015 |
Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway.
Topics: Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; E1A-Associated p300 Protein; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Metformin; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
BIOAVAILABILITY AND METABOLISM OF GRAPE TRANS-RESVERATROL ON CACO-2 CELLS.
Topics: Biological Availability; Caco-2 Cells; Endothelial Cells; Humans; Resveratrol; Stilbenes; Vitis | 2015 |
Resveratrol Ameliorates Clonidine-Induced Endothelium-Dependent Relaxation Involving Akt and Endothelial Nitric Oxide Synthase Regulation in Type 2 Diabetic Mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antioxidants; Clonidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Synergism; Endothelium, Vascular; Male; Mice, Inbred ICR; Nitric Oxide Synthase; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Vasodilation | 2015 |
Effect of Resveratrol Treatment on the Pharmacokinetics of Diclofenac in Healthy Human Volunteers.
Topics: Administration, Oral; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C9; Diclofenac; Half-Life; Healthy Volunteers; Herb-Drug Interactions; Humans; Male; Plant Extracts; Resveratrol; Stilbenes; Young Adult | 2016 |
Improved Antioxidant Capacity of Optimization of a Self-Microemulsifying Drug Delivery System for Resveratrol.
Topics: Animals; Antioxidants; Biological Availability; Cell Proliferation; Drug Carriers; Drug Delivery Systems; Emulsions; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2015 |
Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Cytochrome P-450 CYP1A1; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Quinazolines; Resveratrol; Stilbenes | 2015 |
Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fibroblasts; Fibrosis; Forkhead Box Protein O1; Forkhead Transcription Factors; Genetic Therapy; GPI-Linked Proteins; Hemochromatosis Protein; Humans; Iron Overload; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Myocardium; Myocytes, Cardiac; Oxidants; Oxidative Stress; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation.
Topics: Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Cell Death; Cognition; Extracellular Matrix Proteins; GABAergic Neurons; Gene Expression Regulation; Hippocampus; Inflammation; Interneurons; Longevity; Male; Microglia; Nerve Degeneration; Nerve Tissue Proteins; Neurogenesis; Neuropeptide Y; Oxidative Stress; Parvalbumins; Rats, Inbred F344; Reelin Protein; Resveratrol; Seizures; Serine Endopeptidases; Somatostatin; Status Epilepticus; Stilbenes; Tumor Necrosis Factor-alpha | 2015 |
Simple low-cost miniaturization approach for pharmaceutical nanocrystals production.
Topics: Apigenin; Ascorbic Acid; Chemistry, Pharmaceutical; Cyclosporine; Hesperidin; Miniaturization; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Suspensions; Technology, Pharmaceutical | 2016 |
Effects of resveratrol on collagen type II protein in the superficial and middle zone chondrocytes of porcine articular cartilage.
Topics: Animals; Arthritis; Cartilage, Articular; Chondrocytes; Collagen Type II; Immunohistochemistry; Resveratrol; RNA, Messenger; Stilbenes; Swine | 2016 |
3,5,4'-Tri-O-acetylresveratrol Attenuates Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome via MAPK/SIRT1 Pathway.
Topics: Acetates; Animals; Capillary Permeability; Cells, Cultured; Inflammation Mediators; Lipopolysaccharides; Lung; Male; MAP Kinase Signaling System; Mice; Respiratory Distress Syndrome; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
Validated LC-MS/MS method for simultaneous quantification of resveratrol levels in mouse plasma and brain and its application to pharmacokinetic and brain distribution studies.
Topics: Animals; Biological Availability; Brain; Chromatography, Liquid; Drug Carriers; Drug Stability; Injections, Intravenous; Lipids; Liquid-Liquid Extraction; Male; Mice, Inbred BALB C; Nanoparticles; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry; Tissue Distribution | 2016 |
Resveratrol partially prevents oxidative stress and metabolic dysfunction in pregnant rats fed a low protein diet and their offspring.
Topics: Animals; Antioxidants; Female; Insulin; Leptin; Liver; Male; Metabolic Diseases; Oxidative Stress; Placenta; Pregnancy; Prenatal Exposure Delayed Effects; Prenatal Nutritional Physiological Phenomena; Protein Deficiency; Rats; Rats, Wistar; Resveratrol; Sex Factors; Stilbenes | 2016 |
Trans-resveratrol induces a potential anti-lipogenic effect in lipopolysaccharide-stimulated enterocytes.
Topics: Amphiregulin; Anticholesteremic Agents; Caco-2 Cells; Cell Death; Cholesterol; Coenzyme A Ligases; EGF Family of Proteins; Enterocytes; Gene Expression Profiling; Gene Expression Regulation; Humans; Inhibitor of Differentiation Protein 1; Kruppel-Like Transcription Factors; Lipase; Lipogenesis; Lipopolysaccharides; Membrane Proteins; Microarray Analysis; NADPH Oxidase 1; NADPH Oxidases; Phosphoproteins; Proteins; Resveratrol; Signal Transduction; Stilbenes | 2015 |
[Optimization and in vitro characterization of resveratrol-loaded poloxamer 403/407 mixed micelles].
Topics: Drug Carriers; Fluorescence; Kinetics; Micelles; Particle Size; Poloxamer; Resveratrol; Solubility; Stilbenes; Water | 2015 |
Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Organoplatinum Compounds; Oxaliplatin; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2015 |
Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Doxorubicin; Gene Expression Regulation; Humans; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2016 |
Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
Topics: Aminophenols; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Polymerization; Resveratrol; Stilbenes; Structure-Activity Relationship; Sulfonamides; Tubulin; Tubulin Modulators | 2016 |
Aloe vera and Vitis vinifera improve wound healing in an in vivo rat burn wound model.
Topics: Aloe; Animals; Anthraquinones; Burns; Cell Line; Cell Proliferation; Cytokines; Disease Models, Animal; Humans; Interleukin-1beta; Male; Mice, Inbred BALB C; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A; Vitis; Wound Healing | 2016 |
Resveratrol Prevents Retinal Dysfunction by Regulating Glutamate Transporters, Glutamine Synthetase Expression and Activity in Diabetic Retina.
Topics: Animals; Cells, Cultured; Diabetic Retinopathy; Electroretinography; Ependymoglial Cells; Excitatory Amino Acid Transporter 1; Glucose; Glutamate-Ammonia Ligase; Rats, Sprague-Dawley; Resveratrol; Retina; Stilbenes | 2016 |
Stability of Trans-Resveratrol Encapsulated in a Protein Matrix Produced Using Spray Drying to UV Light Stress and Simulated Gastro-Intestinal Digestion.
Topics: Capsules; Caseins; Desiccation; Digestion; Drug Compounding; Drug Delivery Systems; Drug Stability; Gastrointestinal Tract; Humans; In Vitro Techniques; Models, Biological; Polyphenols; Resveratrol; Stilbenes; Ultraviolet Rays; Whey Proteins | 2016 |
Sirtuin 1 modulation in rat model of acetaminophen-induced hepatotoxicity.
Topics: Acetaminophen; Animals; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hepatocytes; Male; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes | 2015 |
The effect of in vivo resveratrol supplementation in irradiated mice on the induction of micronuclei in peripheral blood and bone marrow reticulocytes.
Topics: Animals; Blood Cells; Bone Marrow Cells; Gamma Rays; Male; Mice; Micronuclei, Chromosome-Defective; Micronucleus Tests; Radiation-Protective Agents; Resveratrol; Reticulocytes; Stilbenes | 2016 |
Resveratrol preserves the function of human platelets stored for transfusion.
Topics: Animals; Apoptosis; Blood Platelets; Blood Preservation; Cyclooxygenase Inhibitors; Drug Evaluation; Hemostasis; Humans; Inflammation Mediators; Male; Mice, Inbred C57BL; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Transfusion; Resveratrol; Stilbenes | 2016 |
Resveratrol Directly Binds to Mitochondrial Complex I and Increases Oxidative Stress in Brain Mitochondria of Aged Mice.
Topics: Age Factors; Animals; Binding Sites; Brain; Cell Respiration; Cells, Cultured; Dose-Response Relationship, Drug; Electron Transport Complex I; Gene Expression Regulation, Enzymologic; Humans; Male; Mice; Mitochondria; Models, Molecular; Molecular Docking Simulation; NAD; Oxidative Stress; Resveratrol; Stilbenes | 2015 |
Characterization of the 5'-flanking region of the human TP53 gene and its response to the natural compound, Resveratrol.
Topics: 5' Flanking Region; Antioxidants; Binding Sites; Cellular Senescence; DNA Helicases; Gene Expression Regulation; HeLa Cells; Humans; Luciferases; Mutation; Promoter Regions, Genetic; Resveratrol; Sequence Deletion; Stilbenes; Tumor Suppressor Protein p53 | 2016 |
Synergistic effect of PEGylated resveratrol on delivery of anticancer drugs.
Topics: Antineoplastic Agents; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Synergism; HeLa Cells; Humans; MCF-7 Cells; Polyethylene Glycols; Resveratrol; Stilbenes | 2016 |
Resveratrol reduces IL-6 and VEGF secretion from co-cultured A549 lung cancer cells and adipose-derived mesenchymal stem cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Humans; Interleukin-6; Lung Neoplasms; Mesenchymal Stem Cells; Resveratrol; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2016 |
Dual drug loaded nanoliposomal chemotherapy: A promising strategy for treatment of head and neck squamous cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Doxorubicin; Head and Neck Neoplasms; Humans; Liposomes; Nanoparticles; Resveratrol; Stilbenes | 2016 |
Potassium Hexacyanoferrate (III)-Catalyzed Dimerization of Hydroxystilbene: Biomimetic Synthesis of Indane Stilbene Dimers.
Topics: Biomimetics; Catalysis; Dimerization; Ferricyanides; Indans; Oxidation-Reduction; Resveratrol; Sodium Acetate; Stilbenes | 2015 |
Resveratrol Enhances Neuroplastic Changes, Including Hippocampal Neurogenesis, and Memory in Balb/C Mice at Six Months of Age.
Topics: Animals; Cell Differentiation; Doublecortin Domain Proteins; Doublecortin Protein; Female; Gene Expression Regulation; Hippocampus; Memory; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Neurogenesis; Neuronal Plasticity; Neurons; Neuropeptides; Protein Kinase C; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2015 |
Resveratrol, a potential radiation sensitizer for glioma stem cells both in vitro and in vivo.
Topics: AC133 Antigen; Animals; Antigens, CD; Apoptosis; Autophagy; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; DNA Damage; Glioblastoma; Glycoproteins; Humans; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Peptides; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2015 |
Resveratrol exerts anti-obesity effects in high-fat diet obese mice and displays differential dosage effects on cytotoxicity, differentiation, and lipolysis in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Anti-Obesity Agents; Cell Death; Cell Differentiation; Diet, High-Fat; Dose-Response Relationship, Drug; Lipolysis; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Resveratrol; Stilbenes | 2016 |
Improved oral delivery of resveratrol from N-trimethyl chitosan-g-palmitic acid surface-modified solid lipid nanoparticles.
Topics: Administration, Oral; Animals; Biological Availability; Chitosan; Diglycerides; Drug Carriers; Drug Compounding; Drug Liberation; Fats; Hydrophobic and Hydrophilic Interactions; Kinetics; Male; Mice; Mice, Inbred BALB C; Nanoparticles; NIH 3T3 Cells; Oils; Palmitic Acid; Polysorbates; Resveratrol; Solubility; Stilbenes | 2016 |
Effects of Ethanol on the Expression Level of Various BDNF mRNA Isoforms and Their Encoded Protein in the Hippocampus of Adult and Embryonic Rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Ethanol; Exons; Female; Hippocampus; Pregnancy; Protein Isoforms; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2015 |
Resveratrol triggers ER stress-mediated apoptosis by disrupting N-linked glycosylation of proteins in ovarian cancer cells.
Topics: Activating Transcription Factor 6; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; eIF-2 Kinase; Endoplasmic Reticulum Stress; Enzyme Activation; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Glycosylation; Humans; Neoplasm Proteins; Oncogene Proteins; Ovarian Neoplasms; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrophosphatases; Resveratrol; Signal Transduction; Stilbenes; Time Factors; Transcription Factor CHOP; Transfection | 2016 |
Protective effects of fenofibrate and resveratrol in an aggressive model of rheumatoid arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Antirheumatic Agents; Arthritis, Experimental; Biomarkers; Cytokines; Dexamethasone; Female; Fenofibrate; Freund's Adjuvant; Immunosuppressive Agents; Inflammation Mediators; Joints; Methotrexate; Oxidative Stress; Rats, Wistar; Resveratrol; Spleen; Stilbenes | 2016 |
BDNFVal66met polymorphism: a potential bridge between depression and thrombosis.
Topics: Animals; Anxiety Disorders; Aorta; Blood Coagulation; Brain-Derived Neurotrophic Factor; Carotid Arteries; Carotid Artery Thrombosis; Depressive Disorder; Disease Models, Animal; Female; Heterozygote; Homozygote; Humans; Male; Mice, Transgenic; Middle Aged; Myocardial Ischemia; Nerve Tissue Proteins; Platelet Activation; Platelet Aggregation Inhibitors; Polymorphism, Single Nucleotide; Receptors, Cell Surface; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Thrombosis | 2017 |
Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway.
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Hedgehog Proteins; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Pancreatic Neoplasms; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Urokinase-Type Plasminogen Activator | 2016 |
A facile green approach to prepare core-shell hybrid PLGA nanoparticles for resveratrol delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Calorimetry, Differential Scanning; Cell Line, Tumor; Chlorocebus aethiops; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes; Vero Cells | 2016 |
Resveratrol protects mice from paraquat-induced lung injury: The important role of SIRT1 and NRF2 antioxidant pathways.
Topics: Animals; Antioxidants; Catalase; Glutathione; Heme Oxygenase-1; Lung; Lung Injury; Male; Malondialdehyde; Mice; NF-E2-Related Factor 2; Paraquat; Protective Agents; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase; Up-Regulation | 2016 |
Resveratrol induces apoptosis through modulation of the Akt/FoxO3a/Bim pathway in HepG2 cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Nucleus; Cell Survival; Forkhead Box Protein O3; Forkhead Transcription Factors; Hep G2 Cells; Humans; Membrane Proteins; Phosphorylation; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2016 |
A study of retention characteristics and quality control of nutraceuticals containing resveratrol and polydatin using fused-core column chromatography.
Topics: Acetonitriles; Chromatography, High Pressure Liquid; Dietary Supplements; Glucosides; Indicators and Reagents; Nitrophenols; Quality Control; Resveratrol; Solutions; Stilbenes | 2016 |
SIRT1 regulates accumulation of oxidized LDL in HUVEC via the autophagy-lysosomal pathway.
Topics: Autophagy; Autophagy-Related Protein 5; Blotting, Western; Cells, Cultured; Chloroquine; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Lysosomes; Microscopy, Fluorescence; Microtubule-Associated Proteins; Niacinamide; Resveratrol; RNA Interference; Sequestosome-1 Protein; Signal Transduction; Sirtuin 1; Stilbenes; Vitamin B Complex | 2016 |
SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cardiomyopathies; Cells, Cultured; Diastole; Disease Models, Animal; Doxorubicin; Female; Fibrosis; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Resveratrol Induces Apoptosis-Like Death and Prevents In Vitro and In Vivo Virulence of Entamoeba histolytica.
Topics: Apoptosis; Calcium; Calpain; DNA Fragmentation; Entamoeba histolytica; Lipid Peroxidation; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Trophozoites; Virulence | 2016 |
Resveratrol Improved Flow-Mediated Outward Arterial Remodeling in Ovariectomized Rats with Hypertrophic Effect at High Dose.
Topics: Animals; Atrial Remodeling; Endothelium, Vascular; Female; Membrane Glycoproteins; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Contraction; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type III; Ovariectomy; Oxidative Stress; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxides; Vasodilator Agents | 2016 |
[Effects of resveratrol on Nrf2 signal pathway of chronic lead-exposed mouse brain tissue].
Topics: Animals; Brain; Lead Poisoning; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats.
Topics: Animals; Animals, Newborn; Antioxidants; Brain Ischemia; Female; Hedgehog Proteins; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Resveratrol; Signal Transduction; Stilbenes; Stroke; Treatment Outcome | 2017 |
Resveratrol can prevent CCl₄-induced liver injury by inhibiting Notch signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Female; Immunohistochemistry; In Situ Nick-End Labeling; Rats; Rats, Wistar; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Effects of resveratrol on the structure and fluidity of lipid bilayers: a membrane biophysical study.
Topics: Biological Transport; Cholesterol; Kinetics; Lipid Bilayers; Liposomes; Membrane Fluidity; Resveratrol; Stilbenes; Thermodynamics | 2016 |
Juglone up-regulates sirt1 in skin cells under normal and UVB irradiated conditions.
Topics: Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Keratinocytes; Naphthoquinones; NIMA-Interacting Peptidylprolyl Isomerase; Resveratrol; Signal Transduction; Sirtuin 1; Skin; Stilbenes; Ultraviolet Rays; Up-Regulation | 2016 |
Effects of resveratrol and methoxyamine on the radiosensitivity of iododeoxyuridine in U87MG glioblastoma cell line.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Colony-Forming Units Assay; Comet Assay; Gamma Rays; Humans; Hydroxylamines; Idoxuridine; Neuroglia; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Stilbenes | 2016 |
Resveratrol Ameliorates the Components of Hepatic Inflammation and Apoptosis in a Rat Model of Streptozotocin-Induced Diabetes.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers; Diabetes Mellitus, Experimental; Erythropoietin; Gene Expression Regulation; Interleukins; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin; Tumor Necrosis Factor-alpha | 2016 |
TRPA1 channels as targets for resveratrol and related stilbenoids.
Topics: Animals; Calcium; HEK293 Cells; Humans; Inhibitory Concentration 50; Ion Transport; Protein Binding; Rats; Resveratrol; Stilbenes; TRPA1 Cation Channel; TRPC Cation Channels | 2016 |
Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice.
Topics: Animals; Antioxidants; Cell Adhesion Molecules; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Heart; Male; MAP Kinase Signaling System; Mice; Myocardium; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Transforming Growth Factor beta | 2016 |
LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol.
Topics: Adipose Tissue; Animals; Antioxidants; Blood Glucose; Body Weight; Epididymis; Gene Expression Profiling; Glucose; Glucose Tolerance Test; Homeostasis; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Leukocytes; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Obesity; Osmosis; Resveratrol; Stilbenes | 2016 |
Resveratrol Protects and Restores Endothelium-Dependent Relaxation in Hypercholesterolemic Rabbit Corpus Cavernosum.
Topics: Animals; Cholesterol, Dietary; Disease Models, Animal; Endothelium; Erectile Dysfunction; Hypercholesterolemia; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Penis; Rabbits; Resveratrol; Stilbenes | 2016 |
Prominent efficiency in skin delivery of resveratrol by novel sucrose oleate microemulsion.
Topics: Administration, Cutaneous; Drug Delivery Systems; Emulsions; Excipients; Myristates; Oleic Acid; Resveratrol; Skin; Skin Absorption; Solubility; Stilbenes; Sucrose; Surface-Active Agents; Water | 2016 |
Negative ion electrospray high-resolution tandem mass spectrometry of polyphenols.
Topics: Anthraquinones; Apigenin; Flavanones; Flavones; Flavonols; Isoflavones; Luteolin; Phloroglucinol; Polyphenols; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Tandem Mass Spectrometry | 2016 |
AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Topics: Animals; beta-Transducin Repeat-Containing Proteins; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Female; Heterocyclic Compounds, 3-Ring; Humans; Mice; Mice, Inbred BALB C; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Twist-Related Protein 1 | 2016 |
Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition.
Topics: Aspirin; Curcumin; Hydrophobic and Hydrophilic Interactions; Islet Amyloid Polypeptide; Models, Molecular; Molecular Conformation; Nanostructures; Polyphenols; Protein Aggregates; Protein Aggregation, Pathological; Protein Binding; Resveratrol; Stilbenes | 2016 |
Amphiphilic nanoparticles of resveratrol-norcantharidin to enhance the toxicity in zebrafish embryo.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Carriers; Embryo, Nonmammalian; Hydrophobic and Hydrophilic Interactions; Liposomes; Medicine, Chinese Traditional; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Zebrafish | 2016 |
Resveratrol Regulates Mitochondrial Biogenesis and Fission/Fusion to Attenuate Rotenone-Induced Neurotoxicity.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Shape; Cell Survival; DNA, Mitochondrial; Gene Dosage; Male; Mitochondria; Mitochondrial Dynamics; Motor Activity; Neuroprotective Agents; Neurotoxins; Organelle Biogenesis; PC12 Cells; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Rotarod Performance Test; Rotenone; Stilbenes; Survival Analysis; Transcription Factors; Transcription, Genetic | 2016 |
ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Lung; Lung Neoplasms; Mitochondria; Oxides; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol-induced autophagy promotes survival and attenuates doxorubicin-induced cardiotoxicity.
Topics: AMP-Activated Protein Kinases; Animals; Antibiotics, Antineoplastic; Autophagy; Cardiotoxicity; Cell Line; Cell Survival; Doxorubicin; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol preferentially inhibits IgE-dependent PGD2 biosynthesis but enhances TNF production from human skin mast cells.
Topics: Animals; Cyclooxygenase 2; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Hypersensitivity; Immunoglobulin E; MAP Kinase Signaling System; Mast Cells; Mice; Prostaglandin D2; Resveratrol; Skin; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Combined 1,25-Dihydroxy-vitamin D and Resveratrol: A Novel Therapeutic Approach to Ameliorate Ischemia Reperfusion-Induced Myocardial Injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Calcium; Drug Therapy, Combination; Male; Myocardial Infarction; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Resveratrol; RNA, Messenger; Stilbenes; Vitamin D; Vitamins | 2015 |
The endocannabinoid system and NGF are involved in the mechanism of action of resveratrol: a multi-target nutraceutical with therapeutic potential in neuropsychiatric disorders.
Topics: Amitriptyline; Animals; Antioxidants; Brain; Camphanes; Cannabinoids; Clonazepam; Dose-Response Relationship, Drug; Endocannabinoids; Male; Nerve Growth Factor; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol-4‑O-D‑(2'-galloyl)-glucopyranoside exerts an anticancer effect on leukemia cells via inducing apoptosis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Flow Cytometry; Glucosides; Leukemia; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
Genetic transformation of a fruit-specific, highly expressed stilbene synthase gene from Chinese wild Vitis quinquangularis.
Topics: Acyltransferases; Ascomycota; Disease Resistance; Fruit; Plant Diseases; Plants, Genetically Modified; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Transformation, Genetic; Vitis | 2016 |
Resveratrol Enhances Apoptosis in Endometriotic Stromal Cells.
Topics: Apoptosis; Cells, Cultured; Endometriosis; Endometrium; Female; Humans; Inhibitor of Apoptosis Proteins; Resveratrol; Stilbenes; Stromal Cells; Survivin; TNF-Related Apoptosis-Inducing Ligand | 2016 |
Facile large-scale preparation of mesoporous silica microspheres with the assistance of sucrose and their drug loading and releasing properties.
Topics: Drug Carriers; Drug Compounding; Drug Liberation; Ibuprofen; Microspheres; Porosity; Resveratrol; Silicon Dioxide; Solubility; Stilbenes; Sucrose | 2016 |
Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats.
Topics: Animals; Antioxidants; Dendrites; Hippocampus; Male; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol fails to affect cocaine conditioned place preference behavior, but alleviates anxiety-like behaviors in cocaine withdrawn rats.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Conditioning, Operant; Cytokines; Hippocampus; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Substance Withdrawal Syndrome | 2016 |
Self-emulsifying drug delivery systems as a tool to improve solubility and bioavailability of resveratrol.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Diabetes Mellitus, Experimental; Drug Delivery Systems; Drug Liberation; Emulsions; Excipients; Hypoglycemic Agents; Male; Particle Size; Rats; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Surface-Active Agents; Thermodynamics | 2016 |
Resveratrol Protects against TNF-α-Induced Injury in Human Umbilical Endothelial Cells through Promoting Sirtuin-1-Induced Repression of NF-KB and p38 MAPK.
Topics: CD40 Antigens; Human Umbilical Vein Endothelial Cells; Humans; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Umbilical Veins | 2016 |
Resveratrol exerts antidepressant properties in the chronic unpredictable mild stress model through the regulation of oxidative stress and mTOR pathway in the rat hippocampus and prefrontal cortex.
Topics: Animals; Antidepressive Agents; Brain; Chronic Disease; Depression; Disease Models, Animal; Exploratory Behavior; Food Preferences; Lipid Peroxidation; Locomotion; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Stress, Psychological; Swimming; Time Factors; TOR Serine-Threonine Kinases | 2016 |
[The effect of resveratrol on paraquat-induced acute lung injury in mice and its mechanism].
Topics: Acute Lung Injury; Animals; Apoptosis; Interleukin-1beta; Interleukin-6; Lung; Male; Mice; Mice, Inbred ICR; NF-kappa B; Paraquat; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Skin Delivery and in Vitro Biological Evaluation of Trans-Resveratrol-Loaded Solid Lipid Nanoparticles for Skin Disorder Therapies.
Topics: Calorimetry, Differential Scanning; Cell Line; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Humans; Lipids; Nanoparticles; Particle Size; Permeability; Resveratrol; Skin; Skin Diseases; Stilbenes | 2016 |
The Scavenging of DPPH, Galvinoxyl and ABTS Radicals by Imine Analogs of Resveratrol.
Topics: Benzhydryl Compounds; Benzothiazoles; Biphenyl Compounds; Free Radical Scavengers; Molecular Structure; Picrates; Resveratrol; Stilbenes; Sulfonic Acids | 2016 |
Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; K562 Cells; Neoplasms, Experimental; Resveratrol; Sphingomyelin Phosphodiesterase; Stilbenes; Transcriptional Activation; Up-Regulation | 2016 |
Obesity Weighs down Memory through a Mechanism Involving the Neuroepigenetic Dysregulation of Sirt1.
Topics: Animals; Antioxidants; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; DNA Methylation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Insulin; Male; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Obesity; Prosencephalon; Recognition, Psychology; Resveratrol; Sirtuin 1; Spatial Memory; Stilbenes; Time Factors | 2016 |
Resveratrol and its methoxy-derivatives as modulators of DNA damage induced by ionising radiation.
Topics: Animals; Cell Proliferation; CHO Cells; Cricetulus; DNA; DNA Damage; Mitosis; Radiation, Ionizing; Resveratrol; Stilbenes; Topoisomerase Inhibitors | 2016 |
The role of Resveratrol-induced mitophagy/autophagy in peritoneal mesothelial cells inflammatory injury via NLRP3 inflammasome activation triggered by mitochondrial ROS.
Topics: Autophagy; Carrier Proteins; Cells, Cultured; Epithelial Cells; Humans; Inflammasomes; Inflammation; Mitochondria; Mitophagy; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol augments therapeutic efficiency of mouse bone marrow mesenchymal stem cell-based therapy in experimental autoimmune encephalomyelitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Freund's Adjuvant; L-Lactate Dehydrogenase; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Resveratrol; Severity of Illness Index; Stilbenes; Time Factors | 2016 |
Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cytokines; Female; Gamma Rays; Inflammation; Nitric Oxide Synthase Type II; Ovarian Follicle; Ovarian Reserve; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; PPAR gamma; Primary Ovarian Insufficiency; Radiation Injuries, Experimental; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factor RelA | 2016 |
Resveratrol analogue 4,4'-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis.
Topics: Animals; Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Male; Mice; Neoplasm Invasiveness; Neoplasms, Experimental; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
Dihydro-Resveratrol Ameliorates Lung Injury in Rats with Cerulein-Induced Acute Pancreatitis.
Topics: alpha-Amylases; Animals; Ceruletide; Cytokines; Lung; Lung Diseases; NF-kappa B; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol modulates intestinal morphology and HSP70/90, NF-κB and EGF expression in the jejunal mucosa of black-boned chickens on exposure to circular heat stress.
Topics: Animal Feed; Animals; Chickens; Dietary Supplements; Epidermal Growth Factor; Hot Temperature; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Ileum; Intestinal Mucosa; Jejunum; NF-kappa B; Resveratrol; Stilbenes | 2016 |
Resveratrol induces intracellular Ca(2+) rise via T-type Ca(2+) channels in a mesothelioma cell line.
Topics: Calcium; Calcium Channels, T-Type; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Mesothelioma; Resveratrol; Stilbenes | 2016 |
Potential of Synechocystis PCC 6803 as a novel cyanobacterial chassis for heterologous expression of enzymes in the trans-resveratrol biosynthetic pathway.
Topics: Acyltransferases; Ammonia-Lyases; Biosynthetic Pathways; Gene Expression; Promoter Regions, Genetic; Resveratrol; Stilbenes; Synechocystis | 2016 |
Characterization of NtREL1, a novel root-specific gene from tobacco, and upstream promoter activity analysis in homologous and heterologous hosts.
Topics: Amino Acid Sequence; Base Sequence; Gene Expression Regulation, Plant; Genes, Plant; Glucuronidase; Nicotiana; Organ Specificity; Phylogeny; Plant Proteins; Plant Roots; Plants, Genetically Modified; Promoter Regions, Genetic; Resveratrol; Stilbenes; Transgenes | 2016 |
Oxidative stress plays major role in mediating apoptosis in filarial nematode Setaria cervi in the presence of trans-stilbene derivatives.
Topics: Animals; Apoptosis; Caspases; DNA Fragmentation; Elephantiasis, Filarial; Gene Expression Regulation; Humans; Hydrogen Peroxide; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Setaria Nematode; Stilbenes | 2016 |
Anti-inflammatory and antioxidant properties of a novel resveratrol-salicylate hybrid analog.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Carrageenan; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Hep G2 Cells; Humans; Hydrogen Peroxide; Mice; Molecular Structure; Oxidative Stress; Peritonitis; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Resveratrol; Salicylates; Stilbenes; Structure-Activity Relationship | 2016 |
Pterostilbene carboxaldehyde thiosemicarbazone, a resveratrol derivative inhibits 17β-Estradiol induced cell migration and proliferation in HUVECs.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Estradiol; Female; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Signaling System; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, Estrogen; Receptors, Vascular Endothelial Growth Factor; Resveratrol; Stilbenes; Thiosemicarbazones; Thrombospondin 1; Up-Regulation; Vascular Endothelial Growth Factor A | 2016 |
Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; CD4-Positive T-Lymphocytes; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Leukemic; Humans; Interleukin-2; Jurkat Cells; Leukemia, T-Cell; Prodrugs; Promoter Regions, Genetic; Resveratrol; Stilbenes; Transfection | 2016 |
Alteration of cytokine profile following hemorrhagic shock.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Chemokine CCL3; Cytokines; Gene Expression; Interleukin-10; Interleukin-2; Interleukin-6; Male; Myocardium; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Shock, Hemorrhagic; Stilbenes; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
The enhancement of immune function and activation of NF-κB by resveratrol-treatment in immunosuppressive mice.
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Immunity; Immunization; Immunocompromised Host; Immunosuppression Therapy; Macrophages, Peritoneal; Male; Mice; NF-kappa B; Resveratrol; Stilbenes | 2016 |
Revised structure of trans-resveratrol: Implications for its proposed antioxidant mechanism.
Topics: Antioxidants; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
The antimicrobial action of resveratrol against Listeria monocytogenes in food-based models and its antibiofilm properties.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Biofilms; Chickens; Diet, Fat-Restricted; Food Preservatives; Food Storage; Humans; Lactuca; Listeria; Listeria monocytogenes; Meat Products; Microbial Sensitivity Tests; Microbial Viability; Milk; Plankton; Plant Leaves; Portugal; Refrigeration; Resveratrol; Species Specificity; Stilbenes | 2016 |
Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat.
Topics: Animals; Antioxidants; Autophagy; Blotting, Western; Cell Hypoxia; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Gene Knockdown Techniques; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes | 2016 |
Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cellular Senescence; Diet, High-Fat; Male; Mice; Mitochondria; Neuroprotective Agents; Random Allocation; Resveratrol; Stilbenes; Stress, Physiological; Wnt Signaling Pathway | 2017 |
Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion.
Topics: Animals; Antioxidants; Caloric Restriction; Cells, Cultured; Complement Activation; Complement C3; Disease Models, Animal; Genotype; Isolated Heart Preparation; Mice, Inbred C57BL; Mice, Knockout; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Oxidative Stress; Phenotype; Phosphorylation; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Time Factors; Ventricular Function, Left | 2016 |
Resveratrol provides neuroprotection by inhibiting phosphodiesterases and regulating the cAMP/AMPK/SIRT1 pathway after stroke in rats.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Brain; Brain Infarction; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Male; Neuroprotective Agents; Phosphoric Diester Hydrolases; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Rolipram; Signal Transduction; Sirtuin 1; Stilbenes; Stroke | 2016 |
Resveratrol is equipotent to perindopril in attenuating post-infarct cardiac remodeling and contractile dysfunction in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Male; Myocardial Contraction; Myocardial Infarction; Perindopril; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol Protects against Titanium Particle-Induced Aseptic Loosening Through Reduction of Oxidative Stress and Inactivation of NF-κB.
Topics: Animals; Antioxidants; Catalase; Cell Line; Female; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteolysis; Oxidative Stress; Prostheses and Implants; RAW 264.7 Cells; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Titanium; Tumor Necrosis Factor-alpha | 2016 |
Direct ingestion method for enhancing production and bioavailability of resveratrol and other phytoalexins in Vitis vinifera.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Food; Humans; Models, Theoretical; Phytoalexins; Plant Extracts; Plant Leaves; Rats; Resveratrol; Saliva; Sesquiterpenes; Stilbenes; Vitis | 2016 |
Dietary Phenolic Compounds Interfere with the Fate of Hydrogen Peroxide in Human Adipose Tissue but Do Not Directly Inhibit Primary Amine Oxidase Activity.
Topics: Adipocytes; Adipose Tissue; Adolescent; Adult; Aged; Amine Oxidase (Copper-Containing); Anti-Inflammatory Agents; Antioxidants; Benzylamines; Caffeic Acids; Diet; Female; Fluorometry; Hexoses; Humans; Hydrogen Peroxide; Inflammation; Middle Aged; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidative Stress; Oxygen; Phenols; Quercetin; Resveratrol; Stilbenes; Tyramine; Young Adult | 2016 |
Neuroprotection by combination of resveratrol and enriched environment against ischemic brain injury in rats.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Infarction; Brain Injuries; Disease Models, Animal; Environment; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Locomotion; Male; MAP Kinase Signaling System; Neurologic Examination; Neuroprotective Agents; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Insights into the properties of the two enantiomers of trans-δ-viniferin, a resveratrol derivative: antioxidant activity, biochemical and molecular modeling studies of its interactions with hemoglobin.
Topics: Antioxidants; Benzofurans; Erythrocyte Membrane; Erythrocytes; Free Radical Scavengers; Hemoglobins; Humans; Hydrogen Bonding; Methemoglobin; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Nitrites; Oxidation-Reduction; Oxidative Stress; Protein Binding; Resorcinols; Resveratrol; Stilbenes | 2016 |
Role of apoptosis-related miRNAs in resveratrol-induced breast cancer cell death.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspases; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; X-Linked Inhibitor of Apoptosis Protein | 2016 |
PHYSIOLOGICAL EFFECTS OF RESVERATROL AND COUMARIC ACID ON TWO MAJOR GROUNDNUT PESTS AND THEIR EGG PARASITOID BEHAVIOR.
Topics: Animals; Arachis; Coumaric Acids; Insect Control; Larva; Moths; Resveratrol; Spodoptera; Stilbenes; Wasps | 2016 |
Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars.
Topics: Animals; Cells, Cultured; Cicatrix, Hypertrophic; Disease Models, Animal; Humans; Mice; Mice, Inbred BALB C; Resveratrol; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2016 |
Resveratrol augments ER stress and the cytotoxic effects of glycolytic inhibition in neuroblastoma by downregulating Akt in a mechanism independent of SIRT1.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glycolysis; Humans; Insulin Receptor Substrate Proteins; Neuroblastoma; Phosphatidylinositol 3-Kinases; Protein Phosphatase 1; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2016 |
BRCA1 inhibits AR-mediated proliferation of breast cancer cells through the activation of SIRT1.
Topics: Animals; BRCA1 Protein; Breast Neoplasms; Cell Proliferation; Female; Gene Expression; Genes, BRCA1; Humans; MCF-7 Cells; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Mice, Nude; Prognosis; Receptors, Androgen; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition.
Topics: Adenosine Triphosphate; Amino Acid Motifs; Antineoplastic Agents, Phytogenic; Autophagy; Autophagy-Related Protein-1 Homolog; Binding, Competitive; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genes, Reporter; HEK293 Cells; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins; Luciferases; MCF-7 Cells; Molecular Docking Simulation; Protein Binding; Protein Domains; Protein Structure, Secondary; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2016 |
A novel monolithic controlled delivery system of resveratrol for enhanced hepatoprotection: nanoformulation development, pharmacokinetics and pharmacodynamics.
Topics: Administration, Oral; Animals; Biological Availability; Biomarkers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Stability; Lipids; Liver; Liver Cirrhosis; Male; Nanoparticles; Particle Size; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Suspensions; X-Ray Diffraction | 2016 |
Sequential molecularly imprinted solid-phase extraction methods for the analysis of resveratrol and other polyphenols.
Topics: Arachis; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Industrial Waste; Molecular Imprinting; Polyphenols; Resveratrol; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Water | 2016 |
Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Kidney Neoplasms; Membrane Potential, Mitochondrial; Niacinamide; Phenylurea Compounds; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Resveratrol; S Phase Cell Cycle Checkpoints; Signal Transduction; Sorafenib; STAT3 Transcription Factor; STAT5 Transcription Factor; Stilbenes | 2016 |
Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Disease Models, Animal; Fibrosis; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoblotting; Inflammation; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol reduces matrix metalloproteinases and alleviates intrahepatic cholestasis of pregnancy in rats.
Topics: Animals; Cholestasis, Intrahepatic; Female; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pregnancy; Pregnancy Complications; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Ursodeoxycholic Acid | 2016 |
Chronic in vivo or acute in vitro resveratrol attenuates endothelium-dependent cyclooxygenase-mediated contractile signaling in hypertensive rat carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; AMP-Activated Protein Kinases; Animals; Carotid Artery, Common; Endothelium, Vascular; Hypertension; Male; Muscle Contraction; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Thromboxane; Resveratrol; Signal Transduction; Stilbenes; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2016 |
Repurposing Resveratrol and Fluconazole To Modulate Human Cytochrome P450-Mediated Arachidonic Acid Metabolism.
Topics: Arachidonic Acid; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Drug Repositioning; Fluconazole; Humans; Microsomes, Liver; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2016 |
Effect of resveratrol on the pharmacokinetics of fexofenadine in rats: Involvement of P-glycoprotein inhibition.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Drug Interactions; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Rats, Wistar; Resveratrol; Stilbenes; Terfenadine; Verapamil | 2016 |
Regulation of eIF2α expression and renal interstitial fibrosis by resveratrol in rat renal tissue after unilateral ureteral obstruction.
Topics: Animals; Eukaryotic Initiation Factor-2; Fibrosis; Kidney; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Ureteral Obstruction | 2016 |
Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1β Axis in Microglia.
Topics: Animals; Cell Line; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Microglia; NLR Family, Pyrin Domain-Containing 3 Protein; Resveratrol; Sepsis-Associated Encephalopathy; Stilbenes | 2016 |
Protective effects of resveratrol against cisplatin-induced testicular and epididymal toxicity in rats.
Topics: Animals; Antineoplastic Agents; Cisplatin; Epididymis; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Testis | 2016 |
Protein-Flavonoid Interaction Studies by a Taylor Dispersion Surface Plasmon Resonance (SPR) Technique: A Novel Method to Assess Biomolecular Interactions.
Topics: Binding Sites; Flavonoids; Glutathione S-Transferase pi; Humans; Kaempferols; Kinetics; Luteolin; Protein Binding; Quercetin; Resveratrol; Serum Albumin; Stilbenes; Surface Plasmon Resonance | 2016 |
Perinatal Resveratrol Supplementation to Spontaneously Hypertensive Rat Dams Mitigates the Development of Hypertension in Adult Offspring.
Topics: Adult; Adult Children; Animals; Animals, Newborn; Dietary Supplements; Disease Models, Animal; Female; Humans; Hypertension; Male; Perinatal Care; Pregnancy; Pregnancy, Animal; Random Allocation; Rats; Rats, Inbred SHR; Reference Values; Resveratrol; Stilbenes | 2016 |
Assessment of resveratrol, apocynin and taurine on mechanical-metabolic uncoupling and oxidative stress in a mouse model of duchenne muscular dystrophy: A comparison with the gold standard, α-methyl prednisolone.
Topics: Acetophenones; Animals; Antioxidants; Disease Models, Animal; Male; Methylprednisolone; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NADPH Oxidases; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Taurine | 2016 |
Resveratrol suppresses myofibroblast activity of human buccal mucosal fibroblasts through the epigenetic inhibition of ZEB1 expression.
Topics: Enhancer of Zeste Homolog 2 Protein; Epigenomics; Fibroblasts; Humans; Mouth Mucosa; Mouth Neoplasms; Myofibroblasts; Oral Submucous Fibrosis; Precancerous Conditions; Resveratrol; Stilbenes; Zinc Finger E-box-Binding Homeobox 1 | 2016 |
Resveratrol can both enhance and relax adrenergic contractions of the rat tail artery.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Channels; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stimulation, Chemical; Tail | 2016 |
Resveratrol attenuates neuronal autophagy and inflammatory injury by inhibiting the TLR4/NF-κB signaling pathway in experimental traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Brain; Brain Injuries, Traumatic; Male; Memory; Motor Activity; Neurons; Neuroprotective Agents; NF-kappa B; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Toll-Like Receptor 4 | 2016 |
Comparison between resveratrol and cabergoline in preventing ovarian hyperstimulation syndrome in a rat model.
Topics: Animals; Antioxidants; Cabergoline; Disease Models, Animal; Dopamine Agonists; Ergolines; Female; Ovarian Hyperstimulation Syndrome; Ovary; Random Allocation; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Protective effect of resveratrol against chronic intermittent hypoxia-induced spatial memory deficits, hippocampal oxidative DNA damage and increased p47Phox NADPH oxidase expression in young rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Glutamic Acid; Glutathione; Glutathione Reductase; Hemoglobins; Hippocampus; Hypoxia; Male; Maze Learning; Memory Disorders; NADPH Oxidases; Neuroprotective Agents; Rats; Rats, Wistar; Reaction Time; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2016 |
Resveratrol Potentiates Growth Inhibitory Effects of Rapamycin in PTEN-deficient Lipoma Cells by Suppressing p70S6 Kinase Activity.
Topics: Adipocytes; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; G1 Phase Cell Cycle Checkpoints; Humans; Lipoma; Phosphorylation; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Stilbenes | 2016 |
Co-spray dried resveratrol and budesonide inhalation formulation for reducing inflammation and oxidative stress in rat alveolar macrophages.
Topics: Administration, Inhalation; Aerosols; Animals; Anti-Inflammatory Agents; Antioxidants; Budesonide; Cell Line; Chemistry, Pharmaceutical; Desiccation; Interleukin-6; Lipopolysaccharides; Macrophages, Alveolar; Oxidative Stress; Rats; Resveratrol; Stilbenes; Technology, Pharmaceutical; Tumor Necrosis Factor-alpha | 2016 |
Energy-dependent effects of resveratrol in Saccharomyces cerevisiae.
Topics: Cell Survival; Energy Metabolism; Enzyme Inhibitors; Oxygen Consumption; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2016 |
Piperine potentiates the effects of trans-resveratrol on stress-induced depressive-like behavior: involvement of monoaminergic system and cAMP-dependent pathway.
Topics: Alkaloids; Animals; Behavior, Animal; Benzodioxoles; Cyclic AMP; Depression; Frontal Lobe; Hippocampus; Male; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Stress, Psychological | 2016 |
Resveratrol attenuated TNF-α-induced MMP-3 expression in human nucleus pulposus cells by activating autophagy via AMPK/SIRT1 signaling pathway.
Topics: AMP-Activated Protein Kinases; Autophagy; Blotting, Western; Cells, Cultured; Humans; Matrix Metalloproteinase 3; Nucleus Pulposus; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Trans-Resveratrol Enhances the Anticoagulant Activity of Warfarin in a Mouse Model.
Topics: Animals; Anticoagulants; Antioxidants; Blood Coagulation; Cytochrome P-450 Enzyme System; Disease Models, Animal; Drug Combinations; Drug Synergism; Gene Expression Regulation, Enzymologic; Gnetum; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Plant Extracts; Real-Time Polymerase Chain Reaction; Resveratrol; Seeds; Stilbenes; Warfarin | 2016 |
Production of highly bioactive resveratrol analogues pterostilbene and piceatannol in metabolically engineered grapevine cell cultures.
Topics: Cell Culture Techniques; Gene Expression Regulation, Plant; Metabolic Engineering; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis | 2016 |
Combination Therapy using Co-encapsulated Resveratrol and Paclitaxel in Liposomes for Drug Resistance Reversal in Breast Cancer Cells in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Carriers; Drug Resistance, Multiple; Female; Liposomes; Mice, Inbred BALB C; Paclitaxel; Resveratrol; Stilbenes; Treatment Outcome; Tubulin Modulators | 2016 |
Nanoscale Delivery of Resveratrol towards Enhancement of Supplements and Nutraceuticals.
Topics: Administration, Oral; Caco-2 Cells; Dietary Supplements; Drug Carriers; Drug Compounding; Drug Stability; Humans; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Lipids; Nanoparticles; Nanotechnology; Permeability; Resveratrol; Stilbenes; Time Factors | 2016 |
The Natural Product Resveratrol Inhibits Yeast Cell Separation by Extensively Modulating the Transcriptional Landscape and Reprogramming the Intracellular Metabolome.
Topics: Biological Products; Cell Division; Cell Proliferation; Gene Knockout Techniques; Intracellular Space; Metabolome; Phenotype; Resveratrol; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Stilbenes; Transcription Factors; Transcription, Genetic | 2016 |
Involvement of miR-539-5p in the inhibition of de novo lipogenesis induced by resveratrol in white adipose tissue.
Topics: 3T3-L1 Cells; Adipose Tissue, White; Animals; Down-Regulation; Lipogenesis; Male; Mice; MicroRNAs; PPAR gamma; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Silencing of USP22 suppresses high glucose-induced apoptosis, ROS production and inflammation in podocytes.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Cycle Checkpoints; Cell Proliferation; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Endopeptidases; Gene Expression; Gene Silencing; Glucose; Inflammation Mediators; Matrix Metalloproteinases; Mice; Podocytes; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Ubiquitin Thiolesterase | 2016 |
Resveratrol attenuates neuropathic pain through balancing pro-inflammatory and anti-inflammatory cytokines release in mice.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Humans; Hyperalgesia; Mice; Mice, Inbred BALB C; Microglia; Neuralgia; Neurogenic Inflammation; Resveratrol; Sciatic Nerve; Stilbenes; Th1-Th2 Balance | 2016 |
Determination of trans-resveratrol in Solanum americanum Mill. by HPLC.
Topics: Chromatography, High Pressure Liquid; Fruit; Resveratrol; Solanum; Stilbenes | 2016 |
Seedless synthesis of gold nanorods using resveratrol as a reductant.
Topics: Cetrimonium Compounds; Gold; Nanotubes; Particle Size; Reducing Agents; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2016 |
[Regulatory Effect of Resveratrol on microRNA in Inflammation Reaction].
Topics: Humans; Inflammation; MicroRNAs; Resveratrol; Stilbenes | 2016 |
[Effect of resveratrol on aniogtensin II induced cardiomyocytes hypertrophy and FoxO1/MnSOD signaling pathway].
Topics: Angiotensin II; Animals; Animals, Newborn; Forkhead Transcription Factors; Hypertrophy; Myocytes, Cardiac; Nerve Tissue Proteins; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2015 |
Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells.
Topics: Acetylation; Antineoplastic Agents; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Humans; Ki-67 Antigen; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Oligonucleotides, Antisense; Phosphorylation; Receptors, CXCR4; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Transcription Factor RelA; Transfection | 2016 |
Resveratrol protects PC12 cells against OGD/ R-induced apoptosis via the mitochondrial-mediated signaling pathway.
Topics: Animals; Apoptosis; Calcium; Catalase; Cell Hypoxia; Glucose; Lipid Peroxidation; Malondialdehyde; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; PC12 Cells; Rats; Resveratrol; Signal Transduction; Stilbenes; Superoxide Dismutase | 2016 |
Protection of Bovine Mammary Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Cell Damage by Resveratrol.
Topics: Animals; Antioxidants; Apoptosis; Cattle; Cell Survival; Cells, Cultured; Cytoprotection; Epithelial Cells; Female; Hydrogen Peroxide; Lactation; Mammary Glands, Animal; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol inhibits lipogenesis of 3T3-L1 and SGBS cells by inhibition of insulin signaling and mitochondrial mass increase.
Topics: 3T3-L1 Cells; Acetyl-CoA Carboxylase; Adenosine Triphosphatases; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Antioxidants; ATPases Associated with Diverse Cellular Activities; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Humans; Insulin; Lipogenesis; Mice; Mitochondria; Mitochondrial Proteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol improves the anticancer effects of doxorubicin in vitro and in vivo models: A mechanistic insight.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Doxorubicin; Female; Humans; Male; Mice; NF-kappa B; Resveratrol; Stilbenes | 2016 |
4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, 1 a novel resveratrol analog, differentially regulates estrogen receptors α and β in breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Resveratrol; RNA, Messenger; RNA, Small Interfering; Stilbenes | 2016 |
Inhibition of pancreatic oxidative damage by stilbene derivative dihydro-resveratrol: implication for treatment of acute pancreatitis.
Topics: Acute Disease; alpha-Amylases; Animals; Antioxidants; Blotting, Western; Ceruletide; Cytokines; Inflammation Mediators; Malondialdehyde; Microscopy, Fluorescence; Molecular Structure; NF-kappa B; Oxidative Stress; Pancreas; Pancreatitis; Phosphatidylinositol 3-Kinases; Protein Carbonylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression.
Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Energy Metabolism; Fenofibrate; Fructose; Gene Expression Regulation; Liver; Male; Non-alcoholic Fatty Liver Disease; Rats; Resveratrol; Stilbenes; Time Factors | 2016 |
Resveratrol inhibits Trypanosoma cruzi arginine kinase and exerts a trypanocidal activity.
Topics: Arginine Kinase; Drug Design; Enzyme Inhibitors; Molecular Docking Simulation; Polyphenols; Protein Conformation; Resveratrol; Stilbenes; Trypanocidal Agents; Trypanosoma cruzi | 2016 |
De novo biosynthesis of resveratrol by site-specific integration of heterologous genes in Escherichia coli.
Topics: Acyltransferases; Ammonia-Lyases; Coenzyme A Ligases; Escherichia coli; Genetic Engineering; Glucose; Mutagenesis, Site-Directed; Resveratrol; Stilbenes; Wine | 2016 |
The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Male; Memory Disorders; Mice; Mice, Inbred ICR; Peptide Fragments; Phosphodiesterase 4 Inhibitors; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Micro-CT evaluation of the radioprotective effect of resveratrol on the mandibular incisors of irradiated rats.
Topics: Animals; Imaging, Three-Dimensional; Incisor; Male; Mandible; Odontogenesis; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats, Wistar; Resveratrol; Stilbenes; Time Factors; X-Ray Microtomography | 2016 |
[Study and Evaluation on Preparation of Monolithic Osmotic Pump Tablet of Resveratrol].
Topics: Chemistry, Pharmaceutical; Osmosis; Resveratrol; Solubility; Stilbenes; Tablets | 2015 |
Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes.
Topics: Cell Survival; Chronic Disease; Curcuma; Curcumin; Cytokines; Euterpe; Female; Humans; Hydrogen Peroxide; Inflammation; Jurkat Cells; Lipopolysaccharides; Lymphocytes; Middle Aged; Onions; Polyphenols; Quercetin; Resveratrol; Stilbenes; Tea; Vanillic Acid; Vitis | 2016 |
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
Effect of toasting on non-volatile and volatile vine-shoots low molecular weight phenolic compounds.
Topics: Hot Temperature; Molecular Weight; Phenols; Plant Extracts; Plant Stems; Resveratrol; Stilbenes; Vitis | 2016 |
Protective effect of resveratrol and quercetin on in vitro-induced diabetic mouse corpus cavernosum.
Topics: Acetylcholine; Animals; Arteries; Biological Factors; Cytoprotection; Diabetic Angiopathies; Dose-Response Relationship, Drug; Electric Stimulation; Glucose; In Vitro Techniques; Male; Mice; Nitric Oxide; Penis; Pyruvaldehyde; Quercetin; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents | 2016 |
Effect of Resveratrol on Preventing Steroid-induced Osteonecrosis in a Rabbit Model.
Topics: Animals; Disease Models, Animal; Femur Head Necrosis; Lipopolysaccharides; Magnetic Resonance Imaging; Methylprednisolone; Plasminogen Activator Inhibitor 1; Rabbits; Resveratrol; Stilbenes; Thrombomodulin; Tissue Plasminogen Activator; Vascular Endothelial Growth Factor A | 2016 |
Resveratrol Increases Osteoblast Differentiation In Vitro Independently of Inflammation.
Topics: Cell Differentiation; Cell Lineage; Humans; Inflammation; Mesenchymal Stem Cells; Osteoblasts; Osteocalcin; Osteogenesis; Resveratrol; Stilbenes | 2016 |
Consumer Acceptance of Bars and Gummies with Unencapsulated and Encapsulated Resveratrol.
Topics: Capsules; Caseins; Consumer Behavior; Drug Compounding; Drug Stability; Food; Functional Food; Humans; Polyphenols; Resveratrol; Stilbenes; Taste | 2016 |
Combined high-fat-resveratrol diet and RIP140 knockout mice reveal a novel relationship between elevated bone mitochondrial content and compromised bone microarchitecture, bone mineral mass, and bone strength in the tibia.
Topics: Adaptor Proteins, Signal Transducing; Animals; Body Weight; Bone Density; Bone Resorption; Diet, High-Fat; Male; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Osteoclasts; RANK Ligand; Resveratrol; Stilbenes; Tibia | 2016 |
Inhibitory Effects of Resveratrol on the Human Alveolar Rhabdomyosarcoma Cell Line PLA-802 through Inhibition of the TGF-β1/Smad Signaling Pathway.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Resveratrol; Rhabdomyosarcoma, Alveolar; RNA, Messenger; Signal Transduction; Smad4 Protein; Stilbenes; Transforming Growth Factor beta1 | 2016 |
Synthesis and Biological Evaluation of Novel Resveratrol-NSAID Derivatives as Anti-inflammatory Agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Enzyme-Linked Immunosorbent Assay; Gastric Mucosa; Ibuprofen; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Modulatory effects of resveratrol on endoplasmic reticulum stress-associated apoptosis and oxido-inflammatory markers in a rat model of rotenone-induced Parkinson's disease.
Topics: Animals; Apoptosis; Biomarkers; Caspase 3; Chemically-Induced Disorders; Disease Models, Animal; Endoplasmic Reticulum Stress; Enzyme Activation; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Inflammation; Male; Membrane Proteins; Parkinson Disease; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Rotenone; Stilbenes; Transcription Factor CHOP | 2016 |
Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzamides; Dendrites; Dentate Gyrus; Depression; Disease Models, Animal; Enzyme Inhibitors; Heterocyclic Compounds, 2-Ring; Hippocampus; Imipramine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Naphthols; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Stress, Psychological | 2016 |
Resveratrol lowers blood pressure in spontaneously hypertensive rats via calcium-dependent endothelial NO production.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Pressure; Calcium; Disease Models, Animal; Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Resveratrol; Stilbenes; Vasodilation | 2016 |
A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Antipyrine; Apoptosis; Ascorbic Acid; Autophagy; Edaravone; Gene Expression Regulation; Macrophages; Membrane Potential, Mitochondrial; Mice; Oxidative Stress; Protein Kinases; RAW 264.7 Cells; Reactive Oxygen Species; Resveratrol; Sirolimus; Sirtuin 3; Stilbenes; Stress, Psychological | 2016 |
DNA damage is a late event in resveratrol-mediated inhibition of Escherichia coli.
Topics: Cell Cycle Checkpoints; DNA Damage; Escherichia coli; Genes, Bacterial; Reactive Oxygen Species; Resveratrol; SOS Response, Genetics; Stilbenes | 2016 |
SIRT1 prevents hyperuricemia via the PGC-1α/PPARγ-ABCG2 pathway.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Humans; Hyperuricemia; Ileum; Mice; Neoplasm Proteins; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Uric Acid | 2016 |
Glycosylation of trans-Resveratrol by Cultured Plant Cells under Illumination of LEDs.
Topics: Biotransformation; Cells, Cultured; Glycosylation; Light; Resveratrol; Stereoisomerism; Stilbenes; Strophanthus | 2016 |
Effects of resveratrol and genistein on nuclear factor‑κB, tumor necrosis factor‑α and matrix metalloproteinase‑9 in patients with chronic obstructive pulmonary disease.
Topics: Aged; Aged, 80 and over; Female; Genistein; Humans; Lymphocytes; Male; Matrix Metalloproteinase 9; NF-kappa B; Pulmonary Disease, Chronic Obstructive; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol attenuates inflammatory hyperalgesia by inhibiting glial activation in mice spinal cords.
Topics: Animals; Antigens, Differentiation; Dose-Response Relationship, Drug; Hyperalgesia; Lipopolysaccharides; Male; Mice; Mice, Inbred ICR; Neuroglia; Resveratrol; Spinal Cord; Stilbenes | 2016 |
Gold-conjugated resveratrol nanoparticles attenuate the invasion and MMP-9 and COX-2 expression in breast cancer cells.
Topics: Cell Movement; Cyclooxygenase 2; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gold; Heme Oxygenase-1; Humans; Matrix Metalloproteinase 9; MCF-7 Cells; Nanoconjugates; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2016 |
Impact of Bacillus cereus NRKT on grape ripe rot disease through resveratrol synthesis in berry skin.
Topics: Acyltransferases; Bacillus cereus; Biological Control Agents; Fruit; Gene Expression Regulation, Plant; Plant Diseases; Resveratrol; Stilbenes; Up-Regulation; Vitis | 2017 |
Protective effects of resveratrol on aging-induced cognitive impairment in rats.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Avoidance Learning; Behavior, Animal; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Inflammation; Male; Rats, Wistar; Resveratrol; Spatial Learning; Stilbenes | 2016 |
Antiviral effect of resveratrol in ducklings infected with virulent duck enteritis virus.
Topics: Alphaherpesvirinae; Animals; Antiviral Agents; Cytokines; Ducks; Herpesviridae Infections; Poultry Diseases; Resveratrol; Stilbenes; Viral Load; Virus Replication | 2016 |
Resveratrol Treatment Inhibits Proliferation of and Induces Apoptosis in Human Colon Cancer Cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Indomethacin; Receptors, Prostaglandin; Resveratrol; Stilbenes | 2016 |
Is resveratrol therapeutic when used to treat allergic rhinitisinitis in rats?
Topics: Animals; Male; Nasal Mucosa; Rats; Rats, Wistar; Resveratrol; Rhinitis, Allergic; Stilbenes | 2016 |
Physicochemical properties and antioxidant potential of phosvitin-resveratrol complexes in emulsion system.
Topics: Antioxidants; Emulsions; Hep G2 Cells; Humans; Lipid Peroxidation; Phosvitin; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2016 |
The resveratrol-enriched rice DJ526 boosts motor coordination and physical strength.
Topics: Adipose Tissue; Aging; Animals; Behavior, Animal; Body Weight; Collagen; Crops, Agricultural; Extracellular Matrix; Female; Food, Fortified; Gene Expression Profiling; Mice; Mice, Inbred C57BL; Motor Skills; Muscle Strength; Nutritive Value; Oligonucleotide Array Sequence Analysis; Oryza; Plants, Genetically Modified; Resveratrol; Stilbenes | 2016 |
Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants.
Topics: Anti-Bacterial Agents; Escherichia coli; Genes, Bacterial; Mutation; Reactive Oxygen Species; Resveratrol; Staphylococcus aureus; Stilbenes | 2016 |
Effect of resveratrol analogue, DMU-212, on antioxidant status and apoptosis-related genes in rat model of hepatocarcinogenesis.
Topics: Animals; Antioxidants; Apoptosis; Liver Neoplasms, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota.
Topics: Animals; Atherosclerosis; Bacteria; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Female; Gastrointestinal Microbiome; Humans; Liver; Methylamines; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes | 2016 |
Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 cells through Pim-1.
Topics: Aging; Animals; Glucose; Insulin; Mesenchymal Stem Cells; Proto-Oncogene Proteins c-pim-1; Rats; Resveratrol; Stilbenes; Transfection | 2016 |
Mitochondrial dysfunction in resveratrol-induced apoptosis in QGY-7701 cells.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol alleviates endotoxemia-associated adrenal insufficiency by suppressing oxidative/nitrative stress.
Topics: Adrenal Glands; Adrenal Insufficiency; Animals; Antioxidants; Cytoprotection; Endotoxemia; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Protective effect of resveratrol against aluminum chloride induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Aluminum Chloride; Aluminum Compounds; Animals; Antioxidants; Chlorides; Creatinine; Interleukin-6; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Urea | 2016 |
Vasorelaxing Effect of Resveratrol on Bovine Retinal Arteries.
Topics: Animals; Antioxidants; Cattle; Dose-Response Relationship, Drug; Endothelium, Vascular; Isometric Contraction; Muscle, Smooth, Vascular; Myography; Nitric Oxide; Phorbol 12,13-Dibutyrate; Potassium Channels; Protein Kinase C; Resveratrol; Retinal Artery; Stilbenes; Tetradecanoylphorbol Acetate; Vasodilation; Vasodilator Agents | 2016 |
Partial dealcoholization of red wine by nanofiltration and its effect on anthocyanin and resveratrol levels.
Topics: Alcohols; Anthocyanins; Filtration; Food Handling; Humans; Models, Theoretical; Nanotechnology; Resveratrol; Stilbenes; Taste; Wine | 2016 |
Synergistic effects of resveratrol (free and inclusion complex) and sulfamethoxazole-trimetropim treatment on pathology, oxidant/antioxidant status and behavior of mice infected with Toxoplasma gondii.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Liver; Mice; Oxidants; Oxidative Stress; Resveratrol; Stilbenes; Toxoplasmosis, Animal; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2016 |
Protective Capacity of Resveratrol, a Natural Polyphenolic Compound, against Deoxynivalenol-Induced Intestinal Barrier Dysfunction and Bacterial Translocation.
Topics: Animals; Bacterial Translocation; Cell Line; Cytokines; Inflammation Mediators; Intestinal Mucosa; Intestines; Resveratrol; Stilbenes; Swine; Trichothecenes | 2016 |
The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibrosis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Male; Metformin; Mice; Mice, Inbred ICR; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
Anti-melanogenic effects of resveratryl triglycolate, a novel hybrid compound derived by esterification of resveratrol with glycolic acid.
Topics: alpha-MSH; Animals; Arbutin; Cell Culture Techniques; Cell Line, Tumor; Enzyme Inhibitors; Epidermal Cells; Esterification; Glycolates; Humans; Intramolecular Oxidoreductases; Keratolytic Agents; Melanins; Melanocytes; Membrane Glycoproteins; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Oxidoreductases; Resveratrol; Stilbenes | 2016 |
Generation of Novel Thyroid Cancer Stem-Like Cell Clones: Effects of Resveratrol and Valproic Acid.
Topics: Animals; Antioxidants; Blotting, Western; Cell Culture Techniques; Cell Line, Tumor; Enzyme Inhibitors; Flow Cytometry; Heterografts; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Valproic Acid | 2016 |
Anti-Nociceptive Effect of Resveratrol During Inflammatory Hyperalgesia via Differential Regulation of pro-Inflammatory Mediators.
Topics: Analgesics; Animals; Cyclooxygenase 2; Cytokines; Hyperalgesia; Inflammation Mediators; Male; Nitric Oxide Synthase Type II; Rats; Resveratrol; Spinal Cord; Stilbenes | 2016 |
Colloidal mesoporous silica nanoparticles enhance the biological activity of resveratrol.
Topics: Animals; Calorimetry, Differential Scanning; Cell Line, Tumor; Colloids; Drug Liberation; Humans; Mice; Nanoparticles; Porosity; RAW 264.7 Cells; Resveratrol; Silicon Dioxide; Solubility; Stilbenes; Thermogravimetry; X-Ray Diffraction | 2016 |
Brain-targeted delivery of resveratrol using solid lipid nanoparticles functionalized with apolipoprotein E.
Topics: Apolipoproteins; Blood-Brain Barrier; Brain; Cell Line; Cell Survival; Drug Carriers; Drug Delivery Systems; Humans; Lipids; Nanoparticles; Neuroprotective Agents; Particle Size; Resveratrol; Stilbenes | 2016 |
Molecular insight into the differential anti-androgenic activity of resveratrol and its natural analogs: in silico approach to understand biological actions.
Topics: Androgen Antagonists; Cell Line, Tumor; Computer Simulation; Flutamide; Humans; Hydrogen Bonding; Male; Molecular Conformation; Molecular Dynamics Simulation; Mutant Proteins; Prostatic Neoplasms; Protein Binding; Receptors, Androgen; Resveratrol; Stilbenes; Thermodynamics | 2016 |
Cholesterol induces surface localization of polyphenols in model membranes thus enhancing vesicle stability against lysozyme, but reduces protection of distant double bonds from reactive-oxygen species.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antioxidants; Catechin; Cholesterol; Dimyristoylphosphatidylcholine; Flavanones; Fluorescence Polarization; Hydrophobic and Hydrophilic Interactions; Lignans; Linoleic Acid; Lipid Bilayers; Lipid Peroxidation; Liposomes; Muramidase; Reactive Oxygen Species; Resveratrol; Stilbenes; Surface Properties | 2016 |
Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Head and Neck Neoplasms; Humans; Janus Kinase 1; Janus Kinase 2; Phosphorylation; Radiation-Sensitizing Agents; Resveratrol; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; src-Family Kinases; STAT3 Transcription Factor; Stilbenes; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins | 2016 |
Resveratrol preconditioning protects hepatocytes against hepatic ischemia reperfusion injury via Toll-like receptor 4/nuclear factor-κB signaling pathway in vitro and in vivo.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Disease Models, Animal; Hepatocytes; Humans; Interleukin-1beta; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Dietary Fructose Activates Insulin Signaling and Inflammation in Adipose Tissue: Modulatory Role of Resveratrol.
Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dietary Carbohydrates; Female; Fructose; Gonadal Steroid Hormones; Inflammation; Insulin; Male; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Polydatin ameliorates injury to the small intestine induced by hemorrhagic shock via SIRT3 activation-mediated mitochondrial protection.
Topics: Animals; Disease Models, Animal; Female; Glucosides; Hydrogen Peroxide; Intestine, Small; Male; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Shock, Hemorrhagic; Signal Transduction; Sirtuins; Stilbenes; Superoxide Dismutase | 2016 |
The investigation of resveratrol and analogs as potential inducers of fetal hemoglobin.
Topics: Antioxidants; Cell Survival; Cells, Cultured; Erythroid Precursor Cells; Fetal Hemoglobin; Humans; K562 Cells; Resveratrol; Stilbenes | 2016 |
Resveratrol Promotes Remyelination in Cuprizone Model of Multiple Sclerosis: Biochemical and Histological Study.
Topics: Animals; Biomarkers; Brain; Cuprizone; Disease Models, Animal; Inflammation; Male; Mice, Inbred C57BL; Mitochondria; Motor Activity; Multiple Sclerosis; Myelin Sheath; Oxidative Stress; Remyelination; Resveratrol; Stilbenes | 2017 |
Resveratrol attenuates inflammation-induced hyperexcitability of trigeminal spinal nucleus caudalis neurons associated with hyperalgesia in rats.
Topics: Animals; Hyperalgesia; Inflammation; Male; Neurons; Rats, Wistar; Resveratrol; Stilbenes; Trigeminal Nucleus, Spinal | 2016 |
Resveratrol improves reproductive parameters of adult rats varicocelized in peripuberty.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Infertility, Male; Male; Puberty; Rats; Rats, Wistar; Reproduction; Resveratrol; Sperm Motility; Stilbenes; Testis; Varicocele | 2016 |
Resveratrol Enhances Autophagic Flux and Promotes Ox-LDL Degradation in HUVECs via Upregulation of SIRT1.
Topics: Autophagy; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Lysosomes; Proteolysis; Resveratrol; Sirtuin 1; Stilbenes; Time Factors; Up-Regulation | 2016 |
Resveratrol-loaded nanocapsules inhibit murine melanoma tumor growth.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Melanoma, Experimental; Mice, Inbred C57BL; Nanocapsules; Resveratrol; Stilbenes; Tumor Burden; X-Ray Diffraction | 2016 |
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
Topics: Animals; Apoptosis; Cerebral Cortex; Diet, High-Fat; Dietary Sucrose; Gene Expression Profiling; Inflammation; Macaca mulatta; Male; Neuroprotective Agents; NF-kappa B; Nitric Oxide Synthase Type III; Oxidative Stress; Resveratrol; Stilbenes | 2016 |
Characterization of the 5'-flanking region of the human DNA helicase B (HELB) gene and its response to trans-Resveratrol.
Topics: 5' Flanking Region; Base Sequence; Binding Sites; Cell Line, Tumor; Cloning, Molecular; DNA Helicases; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Proteolysis; Response Elements; Resveratrol; Sp1 Transcription Factor; Stilbenes; Transcription Initiation Site | 2016 |
A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages.
Topics: Animals; Cell Line, Transformed; Cell Survival; Dose-Response Relationship, Drug; Female; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Nitric Oxide; Primary Cell Culture; Resveratrol; Stilbenes | 2017 |
HRD1-Mediated IGF-1R Ubiquitination Contributes to Renal Protection of Resveratrol in db/db Mice.
Topics: Animals; Biomarkers; Body Weight; Cell Line; Chromatography, Liquid; Diabetes Mellitus, Experimental; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Kidney; Male; Mice, Inbred C57BL; Organ Size; Oxidative Stress; Protective Agents; Protein Binding; Proteolysis; Receptor, IGF Type 1; Resveratrol; RNA, Messenger; Stilbenes; Tandem Mass Spectrometry; Transforming Growth Factor beta; Ubiquitin-Protein Ligases; Ubiquitination | 2016 |
The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cells.
Topics: A549 Cells; Adenine; Adenocarcinoma, Bronchiolo-Alveolar; Apoptosis; Autophagosomes; Autophagy; Cisplatin; Drug Synergism; Humans; Lung Neoplasms; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Neoplasm Proteins; Proto-Oncogene Proteins c-akt; Resveratrol; RNA-Binding Proteins; Stilbenes | 2016 |
Distinct metabolic effects of resveratrol on lipogenesis markers in mice adipose tissue treated with high-polyunsaturated fat and high-protein diets.
Topics: Adipogenesis; Adipose Tissue; Animals; Body Composition; Dietary Fats, Unsaturated; Dietary Proteins; Fatty Acids, Unsaturated; Female; Lipogenesis; Mice; Resveratrol; Stilbenes | 2016 |
Effects of polyphenols including curcuminoids, resveratrol, quercetin, pterostilbene, and hydroxypterostilbene on lymphocyte pro-inflammatory cytokine production of senior horses in vitro.
Topics: Age Factors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Curcumin; Cytokines; Flow Cytometry; Horses; Inflammation Mediators; Lymphocytes; Polyphenols; Quercetin; Resveratrol; Stilbenes | 2016 |
Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Blotting, Western; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique; Hyperalgesia; Male; Neuroglia; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Trigeminal Neuralgia | 2016 |
Resveratrol enhances HBV replication through activating Sirt1-PGC-1α-PPARα pathway.
Topics: Animals; Cell Line; Disease Models, Animal; Hepatitis B; Hepatitis B virus; Hepatocytes; Humans; Mice; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Promoter Regions, Genetic; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcriptional Activation; Virus Replication | 2016 |
Resveratrol Requires Red Wine Polyphenols for Optimum Antioxidant Activity.
Topics: Animals; Antioxidants; Humans; Oxidative Stress; Polyphenols; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Wine | 2016 |
Oral Resveratrol Prevents Osteoarthritis Progression in C57BL/6J Mice Fed a High-Fat Diet.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Cartilage, Articular; Chondrocytes; Collagen Type II; Dietary Fats; Dose-Response Relationship, Drug; Gene Expression Regulation; Male; Mice; Mice, Inbred C57BL; Osteoarthritis; Random Allocation; Resveratrol; Stilbenes | 2016 |
Resveratrol Ameliorates Cardiac Hypertrophy by Down-regulation of miR-155 Through Activation of Breast Cancer Type 1 Susceptibility Protein.
Topics: Animals; Blotting, Western; BRCA1 Protein; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation; Immunohistochemistry; Male; Mice; MicroRNAs; Myocytes, Cardiac; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stilbenes | 2016 |
Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs.
Topics: Cell Differentiation; Cell Self Renewal; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Mesenchymal Stem Cells; Neurons; Proliferating Cell Nuclear Antigen; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Umbilical Cord | 2016 |
Resveratrol inhibits cell cycle progression by targeting Aurora kinase A and Polo-like kinase 1 in breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Aurora Kinase A; BRCA1 Protein; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cyclin B1; Cyclin D1; Female; G1 Phase Cell Cycle Checkpoints; Humans; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Resveratrol; Stilbenes; Transcriptome | 2016 |
Combined metformin and resveratrol confers protection against UVC-induced DNA damage in A549 lung cancer cells via modulation of cell cycle checkpoints and DNA repair.
Topics: A549 Cells; Aging; Antineoplastic Agents, Phytogenic; CDC2 Protein Kinase; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 2; Cyclin B1; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA Damage; DNA Repair; G1 Phase Cell Cycle Checkpoints; Histones; Humans; Metformin; Oncogene Proteins; Resveratrol; Retinoblastoma Protein; Ribonucleotide Reductases; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53; Ultraviolet Rays | 2016 |
Neuroprotective effect of resveratrol against brain ischemia reperfusion injury in rats entails reduction of DJ-1 protein expression and activation of PI3K/Akt/GSK3b survival pathway.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Brain Ischemia; Glycogen Synthase Kinase 3 beta; Immunoenzyme Techniques; Male; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protein Deglycase DJ-1; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes | 2016 |
A New Approach to Produce Resveratrol by Enzymatic Bioconversion.
Topics: Alginates; Alternaria; Biotransformation; Enzymes, Immobilized; Glucose; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Resveratrol; Stilbenes; Vitis | 2016 |
Development of a Solid Dispersion System for Improving the Oral Bioavailability of Resveratrol in Rats.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes; Vitis | 2017 |
Neuroprotective effects of resveratrol against traumatic brain injury in rats: Involvement of synaptic proteins and neuronal autophagy.
Topics: Animals; Autophagy; Brain Injuries, Traumatic; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Synapses | 2016 |
Resveratrol attenuates oxidative stress in mitochondrial Complex I deficiency: Involvement of SIRT3.
Topics: Antioxidants; Cells, Cultured; Electron Transport Complex I; ERRalpha Estrogen-Related Receptor; Estrogen Receptor alpha; Fibroblasts; Gene Expression Regulation; Humans; Mitochondria; Mitochondrial Diseases; Oxidative Stress; Oxygen Consumption; Reactive Oxygen Species; Receptors, Estrogen; Resveratrol; Signal Transduction; Sirtuin 3; Stilbenes; Superoxide Dismutase | 2016 |
Resveratrol ameliorates renal injury in spontaneously hypertensive rats by inhibiting renal micro-inflammation.
Topics: Acute Kidney Injury; Animals; beta 2-Microglobulin; Blood Pressure; Collagen Type I; Disease Models, Animal; Fibronectins; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Inflammation; Kidney; Plasminogen Activator Inhibitor 1; Rats; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2016 |
Resveratrol protects the ovary against chromium-toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol.
Topics: Animals; Animals, Newborn; Apoptosis; Carcinogens; Catalase; Chromium; Environmental Pollutants; Estradiol; Female; Follicular Atresia; Glutathione Peroxidase; Kidney; Liver; Oocytes; Ovary; Pregnancy; Progesterone; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Testosterone | 2016 |
Isolation and purification of two antioxidant isomers of resveratrol dimer from the wine grape by counter-current chromatography.
Topics: Antioxidants; Countercurrent Distribution; Dimerization; Resveratrol; Stereoisomerism; Stilbenes; Vitis; Wine | 2016 |
HPLC Methods for Quantitation of Exemestane-Luteolin and Exemestane-Resveratrol Mixtures in Nanoformulations.
Topics: Androstadienes; Antineoplastic Agents; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Humans; Luteolin; Nanoconjugates; Reproducibility of Results; Resveratrol; Stilbenes | 2016 |
The effect of lead exposure on expression of SIRT1 in the rat hippocampus.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Female; Hippocampus; Lead; Male; Maternal-Fetal Exchange; Neuroprotective Agents; Phosphorylation; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes | 2016 |
The combination of 1α,25dihydroxyvitaminD3 with resveratrol improves neuronal degeneration by regulating endoplasmic reticulum stress, insulin signaling and inhibiting tau hyperphosphorylation in SH-SY5Y cells.
Topics: Amyloid beta-Peptides; Anti-Bacterial Agents; Antioxidants; Apoptosis; Blotting, Western; Calcitriol; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Insulin; Neuroblastoma; Neuroprotective Agents; Peptide Fragments; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; tau Proteins; Tumor Cells, Cultured; Tunicamycin; Vitamins | 2016 |
Systemic treatment with resveratrol and/or curcumin reduces the progression of experimental periodontitis in rats.
Topics: Animals; Curcumin; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Gingiva; Immunologic Factors; Interferon-gamma; Interleukin-1beta; Male; Periodontitis; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Enzyme Activators; Fructose; Hypertension; rac1 GTP-Binding Protein; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Encapsulation of piceatannol, a naturally occurring hydroxylated analogue of resveratrol, by natural and modified cyclodextrins.
Topics: Chemical Phenomena; Computational Biology; Cyclodextrins; Entropy; Hydrogen-Ion Concentration; Molecular Docking Simulation; Resveratrol; Stilbenes; Temperature; Thermodynamics | 2016 |
Resveratrol Protects Oxidative Stress-Induced Intestinal Epithelial Barrier Dysfunction by Upregulating Heme Oxygenase-1 Expression.
Topics: Animals; Antioxidants; Bile Ducts; Blotting, Western; Caco-2 Cells; Heme Oxygenase-1; Humans; Hydrogen Peroxide; In Vitro Techniques; Intestinal Mucosa; Jaundice, Obstructive; Ligation; Male; Malondialdehyde; Occludin; Oxidative Stress; Permeability; Phosphorylation; Protein Kinase C; Rats, Wistar; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Tight Junctions; Up-Regulation; Zonula Occludens-1 Protein | 2016 |
Cytotoxic, Antiangiogenic and Antitelomerase Activity of Glucosyl- and Acyl- Resveratrol Prodrugs and Resveratrol Sulfate Metabolites.
Topics: Acylation; Angiogenesis Inhibitors; Antineoplastic Agents; Glycosylation; HT29 Cells; Humans; MCF-7 Cells; Prodrugs; Resveratrol; Stilbenes; Sulfates; Telomerase; Vascular Endothelial Growth Factor A | 2016 |
Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Antioxidants; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; DEAD-box RNA Helicases; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Male; Mechanistic Target of Rapamycin Complex 1; Molecular Targeted Therapy; Multiprotein Complexes; Phosphoproteins; Phosphorylation; Prostate; Proteolysis; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2016 |
A novel enzyme-assisted ultrasonic approach for highly efficient extraction of resveratrol from Polygonum cuspidatum.
Topics: Fallopia japonica; Resveratrol; Stilbenes; Temperature; Ultrasonics | 2016 |
Resveratrol shows neuronal and vascular-protective effects in older, obese, streptozotocin-induced diabetic rats.
Topics: Analgesics; Animals; Antioxidants; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperalgesia; Male; Muscle Contraction; Nervous System; Obesity; Plant Extracts; Polyphenols; Random Allocation; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Resveratrol attenuates monocyte-to-macrophage differentiation and associated inflammation via modulation of intracellular GSH homeostasis: Relevance in atherosclerosis.
Topics: Acetylcysteine; AMP-Activated Protein Kinases; Animals; Antioxidants; Apolipoproteins E; Atherosclerosis; Buthionine Sulfoximine; Cell Differentiation; Glutathione; Homeostasis; Humans; Inflammation; Macrophages; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Monocytes; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells.
Topics: Breast Neoplasms; Cell Line, Tumor; DNA Methylation; Epigenesis, Genetic; Estrogen Receptor alpha; Female; Humans; Promoter Regions, Genetic; Resveratrol; Stilbenes; Tamoxifen | 2016 |
Synthesis of Resveratrol Derivatives and In Vitro Screening for Potential Cancer Chemopreventive Activities.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Biological Assay; Drug Screening Assays, Antitumor; Enzyme Induction; Estrogen Receptor Modulators; Humans; Pentanoic Acids; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
Inhibition of tumor suppressor p53 preserves glycation-serum induced pancreatic beta-cell demise.
Topics: Animals; Antioxidants; Apoptosis; Cell Line; Chromans; Cytoprotection; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Mitochondria; Oxidative Stress; PPAR gamma; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thiazolidinediones; Transcription, Genetic; Troglitazone; Tumor Suppressor Protein p53 | 2016 |
Protective Effects of Chlorogenic Acid and its Metabolites on Hydrogen Peroxide-Induced Alterations in Rat Brain Slices: A Comparative Study with Resveratrol.
Topics: Animals; Antioxidants; Brain; Chlorogenic Acid; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol ameliorates benzo(a)pyrene-induced testicular dysfunction and apoptosis: involvement of p38 MAPK/ATF2/iNOS signaling.
Topics: Activating Transcription Factor 2; Active Transport, Cell Nucleus; Animals; Antioxidants; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Cytochrome P-450 CYP1A1; Dietary Supplements; Dose-Response Relationship, Drug; Environmental Pollutants; Gene Expression Regulation; Infertility, Male; Male; MAP Kinase Signaling System; Nitric Oxide Synthase Type II; Oxidative Stress; Promoter Regions, Genetic; Rats, Wistar; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Testis; Testosterone | 2016 |
Effects of ε-viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa.
Topics: Animals; Benzofurans; Biological Transport; Dose-Response Relationship, Drug; Intestinal Mucosa; Intestine, Large; Intestine, Small; Ion Transport; Male; Permeability; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Topics: Animals; Ataxin-3; Autophagy; Caloric Restriction; Cell Line, Tumor; Cerebellum; Disease Models, Animal; Gait; Inflammation; Machado-Joseph Disease; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutant Proteins; Nervous System; Neurons; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes | 2016 |
Resveratrol reverses diabetes-related decrement in sildenafil-induced relaxation of corpus cavernosum in aged rats.
Topics: Animals; Diabetes Mellitus, Experimental; Drug Synergism; Erectile Dysfunction; Humans; Male; Nitric Oxide; Penis; Phosphodiesterase 5 Inhibitors; Random Allocation; Rats; Rats, Wistar; Resveratrol; Sildenafil Citrate; Stilbenes | 2017 |
Sustained Anti-inflammatory Effect of Resveratrol-Phospholipid Complex Embedded Polymeric Patch.
Topics: Acrylic Resins; Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Carrageenan; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Edema; Inflammation; Male; Permeability; Phospholipids; Polyethylene Glycols; Polymers; Rabbits; Rats; Rats, Wistar; Resveratrol; Skin; Skin Absorption; Stilbenes; Transdermal Patch | 2017 |
Chronic acrylamide exposure in male mice induces DNA damage to spermatozoa; Potential for amelioration by resveratrol.
Topics: Acrylamide; Animals; Antioxidants; Apoptosis; Comet Assay; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; DNA Damage; Male; Mice; Resveratrol; Spermatozoa; Stilbenes; Testis; Tyrosine | 2016 |
Resveratrol Prevents Reactive Oxygen Species-Induced Effects of Light-Emitting Diode-Generated Blue Light in Human Skin Fibroblasts.
Topics: Antioxidants; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Flow Cytometry; Humans; Light; Reactive Oxygen Species; Resveratrol; Skin; Stilbenes | 2016 |
Resveratrol Attenuates Aβ25-35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Autophagy; Cell Survival; Neurons; Neurotoxicity Syndromes; PC12 Cells; Peptide Fragments; Poly (ADP-Ribose) Polymerase-1; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tyrosine-tRNA Ligase; Up-Regulation | 2016 |
Resveratrol Pretreatment Protected against Cerebral Ischemia/Reperfusion Injury in Rats via Expansion of T Regulatory Cells.
Topics: Animals; Antioxidants; Brain; Cytokines; Disease Models, Animal; Drug Administration Schedule; Flow Cytometry; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Spleen; Stilbenes; T-Lymphocytes, Regulatory | 2016 |
Effect of Simvastatin, Coenzyme Q10, Resveratrol, Acetylcysteine and Acetylcarnitine on Mitochondrial Respiration.
Topics: Acetylcarnitine; Acetylcysteine; Animals; Brain; Cell Respiration; Electron Transport Complex IV; Mitochondria; Neuroprotective Agents; Oxygen Consumption; Resveratrol; Simvastatin; Stilbenes; Swine; Ubiquinone | 2016 |
Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cells, Cultured; Chondrocytes; Coculture Techniques; Humans; Inflammation; Interleukin-1beta; Macrophages; Resveratrol; Stilbenes; Time Factors | 2016 |
Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells.
Topics: Autophagy; Cell Line; Cell Survival; Dietary Supplements; Enzyme Inhibitors; Fatty Acids, Omega-3; Gene Expression Regulation; Humans; Leupeptins; Macrolides; Microtubule-Associated Proteins; Resveratrol; RNA-Binding Proteins; Stilbenes | 2016 |
Brief Communication: SIR-2.1-dependent lifespan extension of Caenorhabditis elegans by oxyresveratrol and resveratrol.
Topics: Animals; Blotting, Western; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dose-Response Relationship, Drug; Longevity; Plant Extracts; Resveratrol; Sirtuins; Stilbenes | 2016 |
Resveratrol counters systemic lupus erythematosus-associated atherogenicity by normalizing cholesterol efflux.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; fas Receptor; Humans; Lupus Erythematosus, Systemic; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Resveratrol; Stilbenes | 2016 |
Resveratrol delays polycystic kidney disease progression through attenuation of nuclear factor κB-induced inflammation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemokine CCL2; Disease Progression; Dogs; Humans; Inflammation; Madin Darby Canine Kidney Cells; Male; NF-kappa B; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha; Zebrafish | 2016 |
Effect of resveratrol on progression of polycystic kidney disease: a case of cautious optimism.
Topics: Disease Progression; Humans; Kidney; Polycystic Kidney Diseases; Polycystic Kidney, Autosomal Dominant; Resveratrol; Stilbenes | 2016 |
Re: Resveratrol Reduces the Levels of Circulating Androgen Precursors but has No Effect on Testosterone, Dihydrotestosterone, PSA Levels or Prostate Volume. A 4-Month Randomised Trial in Middle-Aged Men.
Topics: Androgens; Dihydrotestosterone; Humans; Male; Middle Aged; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Resveratrol; Stilbenes; Testosterone | 2016 |
Resveratrol-Loaded Liquid-Crystalline System Inhibits UVB-Induced Skin Inflammation and Oxidative Stress in Mice.
Topics: Animals; Antioxidants; Benzothiazoles; Edema; Female; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Heme Oxygenase-1; Humans; Inflammation; Interleukin-10; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Molecular Structure; Oxidative Stress; Resveratrol; Skin; Stilbenes; Sulfonic Acids; Superoxides; Ultraviolet Rays | 2016 |
New Procedure to Obtain Polyphenol-Enriched Grapes Based on the Use of Chemical Elicitors.
Topics: Acetates; Antioxidants; Cyclopentanes; Ethanol; Flavonoids; Food Handling; Fruit; Glucosides; Oxylipins; Polyphenols; Quercetin; Resveratrol; Rutin; Stilbenes; Vitis | 2016 |
Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity.
Topics: Breast Neoplasms; Cell Line, Tumor; Chromatin; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Nuclear Proteins; Organic Cation Transporter 1; Promoter Regions, Genetic; Receptors, Notch; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators; Transcription Factors; Transcriptional Activation | 2016 |
Electrosprayed nanocomposites based on hyaluronic acid derivative and Soluplus for tumor-targeted drug delivery.
Topics: Administration, Intravenous; Animals; Cell Death; Cell Line, Tumor; Ceramides; Drug Delivery Systems; Drug Liberation; Endocytosis; Fluorescence; Hyaluronic Acid; Male; Mice; Nanocomposites; Polyethylene Glycols; Polyvinyls; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2016 |
Resveratrol attenuates cortical neuron activity: roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels.
Topics: Action Potentials; Animals; Benzimidazoles; Cell Line; Cerebral Cortex; Large-Conductance Calcium-Activated Potassium Channels; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Voltage-Gated Sodium Channels | 2016 |
Influence of canopy-applied chitosan on the composition of organic cv. Sangiovese and Cabernet Sauvignon berries and wines.
Topics: Anthocyanins; Biflavonoids; Catechin; Chitosan; Food, Organic; Fruit; gamma-Aminobutyric Acid; Hydroxybenzoates; Proanthocyanidins; Resveratrol; Solutions; Stilbenes; Vitis; Wine | 2016 |
Effects of Resveratrol Supplementation and Exercise Training on Exercise Performance in Middle-Aged Mice.
Topics: Aging; Animals; Antioxidants; Dietary Supplements; Fatigue; Glycogen; Humans; Mice; Muscle Strength; Muscle, Skeletal; Physical Conditioning, Animal; Resveratrol; Stilbenes; Swimming | 2016 |
Protective mechanisms of resveratrol against methotrexate-induced renal damage may involve BCRP/ABCG2.
Topics: Acute Kidney Injury; Animals; Antimetabolites, Antineoplastic; Antioxidants; ATP Binding Cassette Transporter, Subfamily G, Member 2; Dose-Response Relationship, Drug; Humans; Male; Methotrexate; Neoplasm Proteins; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Evidence supporting the conceptual framework of cancer chemoprevention in canines.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemoprevention; Curcumin; DNA Damage; Dog Diseases; Dogs; Ellagic Acid; Food, Formulated; Genistein; Hydrogen Peroxide; Neoplasms; Oxidative Stress; Quercetin; Resveratrol; Stilbenes; Treatment Outcome | 2016 |
Physicochemical Changes and Glycation Reaction in Intermediate-Moisture Protein-Sugar Foods with and without Addition of Resveratrol during Storage.
Topics: Food Additives; Food Storage; Glucose; Glycation End Products, Advanced; Glycosylation; Maillard Reaction; Resveratrol; Stilbenes; Water; Whey Proteins | 2016 |
Enhancing Topical Delivery of Resveratrol through a Nanosizing Approach.
Topics: Administration, Cutaneous; Animals; Antioxidants; Biological Availability; Drug Delivery Systems; In Vitro Techniques; Nanoparticles; Particle Size; Resveratrol; Skin Absorption; Stilbenes; Swine | 2017 |
Resveratrol promotes differentiation of mouse embryonic stem cells to cardiomyocytes.
Topics: Animals; Biomarkers; Cell Differentiation; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Embryoid Bodies; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Phenotype; Resveratrol; Stilbenes | 2016 |
Combination of Rapamycin and Resveratrol for Treatment of Bladder Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line; Cell Movement; Cell Proliferation; Embryo, Mammalian; Enzyme Activation; Fibroblasts; Humans; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Sirolimus; Stilbenes; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2017 |
[Study on the Interaction in Resveratrol-Hordein Nanoparticle].
Topics: Binding Sites; Energy Transfer; Glutens; Nanoparticles; Protein Binding; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Thermodynamics | 2016 |
Functional/activity network (FAN) analysis of gene-phenotype connectivity liaised by grape polyphenol resveratrol.
Topics: Humans; Phenotype; Protein Interaction Maps; Resveratrol; Stilbenes; Vitis | 2016 |
Investigation of the potential immunomodulatory effects of resveratrol on equine whole blood: An in vitro investigation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Gene Expression Regulation; Horses; Immunity, Innate; Inflammation; Lipopolysaccharides; Phytoalexins; Resveratrol; Sesquiterpenes; Stilbenes; Teichoic Acids; Tumor Necrosis Factor-alpha | 2016 |
Pharmacokinetics, biodistribution, in vitro cytotoxicity and biocompatibility of Vitamin E TPGS coated trans resveratrol liposomes.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Liposomes; Male; Nanomedicine; Polyethylene Glycols; Rats; Resveratrol; Stilbenes; Vitamin E | 2016 |
Anti-inflammatory effect of a resveratrol derivative 3,4,5-trimethoxy-4',5'-dihydroxy-trans-stilbene (WL-09-5) via ROS-mediated NF-κB pathway.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Cytokines; Dinoprostone; Edema; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Sirt 1 activator attenuates the bleomycin-induced lung fibrosis in mice via inhibiting epithelial-to-mesenchymal transition (EMT).
Topics: Animals; Bleomycin; Cadherins; Enzyme Activation; Epithelial-Mesenchymal Transition; Mice; Pulmonary Fibrosis; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
[Polyketone Reaction in Biosynthetic Pathways of 2, 3, 5, 4'-Tetrahydroxy Stilhene-2-O-β-D-glucoside in Polygonum multiflorum by Biocatalysis].
Topics: Acyltransferases; Biocatalysis; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Fallopia multiflora; Glucosides; Mass Spectrometry; Resveratrol; Stilbenes | 2015 |
Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antioxidants; Avoidance Learning; Cerebral Cortex; Convulsants; Dietary Supplements; Encephalitis; Female; Hippocampus; Inflammation Mediators; Kindling, Neurologic; Male; Maze Learning; Mice; Neurons; Neuroprotective Agents; Pentylenetetrazole; Random Allocation; Resveratrol; Seizures; Stilbenes | 2017 |
Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.
Topics: Animals; Anti-Obesity Agents; Antihypertensive Agents; Antioxidants; Biomarkers; Cardiotonic Agents; Cardiovascular Diseases; Diet, High-Fat; Female; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypothyroidism; Mice, Inbred C57BL; Obesity; Oxidative Stress; Quercetin; Random Allocation; Resveratrol; Stilbenes; Thioctic Acid; Thyroid Hormones; Weight Gain | 2016 |
[Effect of Resveratrol Preconditioning on Myocardial Dysfunction after Cardiac Arrest in Rats].
Topics: Animals; Disease Models, Animal; Heart; Heart Arrest; Ischemic Preconditioning; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tyrosine | 2016 |
Metformin and resveratrol inhibit Drp1-mediated mitochondrial fission and prevent ER stress-associated NLRP3 inflammasome activation in the adipose tissue of diabetic mice.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Apoptosis; Cell Differentiation; Diabetes Mellitus, Experimental; Dynamins; Endoplasmic Reticulum Stress; Gene Expression Regulation; Inflammasomes; Metformin; Mice; Mitochondria; Mitochondrial Dynamics; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Lipopolysaccharide Attenuates the Cytotoxicity of Resveratrol in Transformed Mouse Macrophages.
Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Lipopolysaccharides; Macrophages; Mice; RAW 264.7 Cells; Resveratrol; Stilbenes; Toll-Like Receptor 4 | 2016 |
Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways.
Topics: Acetylcysteine; Cell Line, Tumor; Cell Movement; Diabetes Complications; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glucose; Humans; Hyperglycemia; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Pyridines; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol Alleviates Cadmium-Induced Damage and Overexpression of Epidermal Growth Factor Receptor and its Downstream Signaling Proteins in the Reproductive System of Male Swiss Albino Mice.
Topics: Animals; Antioxidants; Cadmium Chloride; Environmental Pollutants; ErbB Receptors; Gene Expression Regulation; Intracellular Signaling Peptides and Proteins; Male; Mice; Resveratrol; Semen; Stilbenes; Testis | 2016 |
A Novel Self-Microemulsifying System for the Simultaneous Delivery and Enhanced Oral Absorption of Curcumin and Resveratrol.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Capsules; Curcumin; Drug Delivery Systems; Emulsions; HT29 Cells; Humans; Oral Mucosal Absorption; Pharmaceutical Vehicles; Rabbits; Resveratrol; Solubility; Stilbenes | 2017 |
LC-MS Guided Isolation of Bioactive Principles from Iris hookeriana and Bioevaluation of Isolates for Antimicrobial and Antioxidant Activities.
Topics: Anti-Bacterial Agents; Antioxidants; Chromatography, Liquid; Flavonols; Glucosides; Iris Plant; Isoflavones; Microbial Sensitivity Tests; Plant Extracts; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2016 |
Resveratrol cocrystals with enhanced solubility and tabletability.
Topics: Benzamides; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Magnetic Resonance Spectroscopy; Models, Molecular; para-Aminobenzoates; Powder Diffraction; Resveratrol; Solubility; Spectroscopy, Fourier Transform Infrared; Stilbenes; Tablets; Temperature; X-Ray Diffraction | 2016 |
Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model.
Topics: Active Transport, Cell Nucleus; Animals; Aorta; Aortic Aneurysm; Apoptosis; Cells, Cultured; Cellular Senescence; Dilatation, Pathologic; Disease Models, Animal; Elastin; Female; Fibrillin-1; Genetic Predisposition to Disease; Human Umbilical Vein Endothelial Cells; Humans; Male; Marfan Syndrome; Mice, Inbred C57BL; Mice, Mutant Strains; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade.
Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Breast; Breast Neoplasms; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice, Nude; Mice, SCID; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Quercetin; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Vitis | 2016 |
Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Apoptosis; bcl-2-Associated X Protein; Collagen Type IV; Deoxyguanosine; Diabetic Nephropathies; Fatty Acids; Fluorescent Antibody Technique; Forkhead Transcription Factors; In Situ Nick-End Labeling; Kidney; Male; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Phenotype; Phosphorylation; PPAR alpha; Receptors, Adiponectin; Resveratrol; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Stilbenes; Transforming Growth Factor beta1; Triglycerides | 2016 |
Local administration of resveratrol inhibits excitability of nociceptive wide-dynamic range neurons in rat trigeminal spinal nucleus caudalis.
Topics: Action Potentials; Analysis of Variance; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Injections, Subcutaneous; Lidocaine; Male; Nociception; Nociceptive Pain; Nociceptors; Physical Stimulation; Rats; Rats, Wistar; Resveratrol; Stilbenes; Trigeminal Nucleus, Spinal | 2016 |
Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylation; alpha-Synuclein; Animals; Autophagy; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine; Male; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neuroprotective Agents; Parkinson Disease, Secondary; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Resveratrol Inhibits Diabetic-Induced Müller Cells Apoptosis through MicroRNA-29b/Specificity Protein 1 Pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Caspase 3; Cells, Cultured; Diabetes Mellitus, Experimental; Ependymoglial Cells; Fructosamine; Gene Expression Regulation; MicroRNAs; Rats, Sprague-Dawley; Resveratrol; Retina; RNA, Messenger; Sp1 Transcription Factor; Stilbenes | 2017 |
In vitro antioxidant activities of resveratrol, cinnamaldehyde and their synergistic effect against cyadox-induced cytotoxicity in rabbit erythrocytes.
Topics: Acrolein; Animals; Antioxidants; Biomarkers; Biphenyl Compounds; Cytoprotection; Dose-Response Relationship, Drug; Drug Synergism; Energy Metabolism; Enzymes; Eryptosis; Erythrocytes; Glutathione; Hemoglobins; Hemolysis; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Picrates; Protein Carbonylation; Quinoxalines; Rabbits; Resveratrol; Stilbenes | 2017 |
Chronic treatment with resveratrol improves overactive bladder in obese mice via antioxidant activity.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Antioxidants; Body Weight; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Muscle, Smooth; NADPH Oxidase 2; NADPH Oxidases; Obesity; Oxidative Stress; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase-1; Time Factors; Urinary Bladder; Urinary Bladder, Overactive | 2016 |
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cerebellar Neoplasms; Combined Modality Therapy; Decitabine; Dideoxynucleosides; Epigenesis, Genetic; Humans; Hydroxamic Acids; Medulloblastoma; Mice; Neurogenesis; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Treatment Outcome; Tretinoin; Valproic Acid; Vorinostat; Xenograft Model Antitumor Assays | 2016 |
Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Obesity Agents; Cells, Cultured; Diet, High-Fat; Enzyme Activation; Inflammation; Insulin; Male; Mice; Niacinamide; Obesity; Proto-Oncogene Proteins c-akt; Regulatory-Associated Protein of mTOR; Resveratrol; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Sirtuin 1; Stilbenes; Subcutaneous Fat; TOR Serine-Threonine Kinases | 2016 |
Resveratrol attenuates peripheral and brain inflammation and reduces ischemic brain injury in aged female mice.
Topics: Adipocytes; Animals; Brain; Brain Ischemia; Encephalitis; Female; Humans; Immunoglobulin G; Inflammation; Interleukin-1beta; Intra-Abdominal Fat; Mice, Inbred C57BL; Postmenopause; Resveratrol; Stilbenes; Stroke; Tumor Necrosis Factor-alpha | 2016 |
[Effect of resveratrol on myocardial energy metabolism in sepsis rats].
Topics: Animals; Energy Metabolism; Heart; Lipopolysaccharides; Mitochondria, Heart; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Sepsis; Stilbenes | 2015 |
Resveratrol Prevents Warm Ischemia-Reperfusion Injury in Liver Grafts From Non-Heart-Beating Donor Rats.
Topics: Animals; Liver Transplantation; Male; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes; Treatment Outcome; Warm Ischemia | 2016 |
Effect of Resveratrol on the Prevention of Intra-Abdominal Adhesion Formation in a Rat Model.
Topics: Abdomen; Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Collagen; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fibrinogen; Interleukin-6; Male; Peritoneum; Postoperative Complications; Rats, Sprague-Dawley; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes; Tissue Adhesions; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2016 |
Tristetraprolin: a novel mediator of the anticancer properties of resveratrol.
Topics: Breast Neoplasms; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; MCF-7 Cells; Nitric Oxide Synthase Type II; Resveratrol; RNA-Binding Proteins; Stilbenes; Tristetraprolin; Vascular Endothelial Growth Factor A | 2016 |
Resveratrol preconditioning induces cerebral ischemic tolerance but has minimal effect on cerebral microRNA profiles.
Topics: Animals; Brain Ischemia; Gene Expression Profiling; Ischemic Preconditioning; Mice; MicroRNAs; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Resveratrol; Stilbenes | 2016 |
The effect of resveratrol on angiotensin II levels and the rate of transcription of its receptors in the rat cardiac hypertrophy model.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart; Male; Myocardium; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Transcription, Genetic | 2017 |
Suppression of microphthalmia-associated transcription factor, but not NF-kappa B sensitizes melanoma specific cell death.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle Checkpoints; Cell Death; Cell Line, Tumor; Cell Proliferation; Down-Regulation; HT29 Cells; Humans; Melanoma; Microphthalmia-Associated Transcription Factor; NF-kappa B; Resveratrol; S Phase; Stilbenes | 2016 |
Intracellular Delivery of Poorly Soluble Polyphenols: Elucidating the Interplay of Self-Assembling Nanocarriers and Human Chondrocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chondrocytes; Curcumin; Drug Carriers; Grape Seed Extract; Humans; Inflammation; Microscopy, Atomic Force; Nanocapsules; Nonlinear Optical Microscopy; Particle Size; Polyphenols; Polysorbates; Resveratrol; Stilbenes; Vitis | 2016 |
Resveratrol Cardioprotection Against Myocardial Ischemia/Reperfusion Injury Involves Upregulation of Adiponectin Levels and Multimerization in Type 2 Diabetic Mice.
Topics: Adiponectin; Animals; Cardiotonic Agents; Diabetes Mellitus, Type 2; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Protein Multimerization; Random Allocation; Resveratrol; Stilbenes; Up-Regulation | 2016 |
Differential responses of Trans-Resveratrol on proliferation of neural progenitor cells and aged rat hippocampal neurogenesis.
Topics: A549 Cells; Aging; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Humans; Neural Stem Cells; Neurogenesis; Phosphorylation; Rats; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Enhanced production of resveratrol derivatives in tobacco plants by improving the metabolic flux of intermediates in the phenylpropanoid pathway.
Topics: Nicotiana; Plant Proteins; Plants, Genetically Modified; Pollination; Resveratrol; Stilbenes | 2016 |
Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue.
Topics: 3T3-L1 Cells; Adipose Tissue; Administration, Oral; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diet, High-Fat; Diglycerides; Fatty Acids; Feeding Behavior; Glucose; Hypoxia; Inflammation; Insulin; Insulin Resistance; Lipolysis; Male; Metformin; Mice; Mice, Inbred ICR; Models, Biological; Muscles; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Therapy with resveratrol attenuates obesity-associated allergic airway inflammation in mice.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Asthma; Cell Movement; Cells, Cultured; Disease Progression; Eosinophils; Lung; Mice; Mice, Inbred Strains; Obesity; Pneumonia; Resveratrol; Stilbenes | 2016 |
The Role of Lipin-1 in the Regulation of Fibrogenesis and TGF-β Signaling in Hepatic Stellate Cells.
Topics: Cell Line, Transformed; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Phosphatidate Phosphatase; Resveratrol; Signal Transduction; Stilbenes; Transforming Growth Factor beta | 2016 |
Resveratrol reverses chronic restraint stress-induced depression-like behaviour: Involvement of BDNF level, ERK phosphorylation and expression of Bcl-2 and Bax in rats.
Topics: Animals; Antidepressive Agents; bcl-2-Associated X Protein; Brain; Brain-Derived Neurotrophic Factor; Extracellular Signal-Regulated MAP Kinases; Male; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Restraint, Physical; Resveratrol; Stilbenes; Stress, Psychological | 2016 |
Tamoxifen synergizes with 4-(E)-{(4-hydroxyphenylimino)-methylbenzene, 1,2-diol} and 4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol}, novel azaresveratrol analogs, in inhibiting the proliferation of breast cancer cells.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Catechols; Cell Proliferation; Cells, Cultured; Drug Synergism; Female; Humans; MCF-7 Cells; Resveratrol; Schiff Bases; Stilbenes; Tamoxifen | 2016 |
Effect and Mechanism of Resveratrol on the Apoptosis of Lung Adenocarcinoma Cell Line A549.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Proliferation; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2015 |
Resveratrol Overcomes Cellular Resistance to Vemurafenib Through Dephosphorylation of AKT in BRAF-mutated Melanoma Cells.
Topics: Antineoplastic Agents; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Inhibitory Concentration 50; Melanoma; Mutation, Missense; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Sulfonamides; Tumor Cells, Cultured; Vemurafenib | 2016 |
Resveratrol lowers synovial hyperplasia, inflammatory markers and oxidative damage in an acute antigen-induced arthritis model.
Topics: Animals; Antioxidants; Arthritis, Experimental; Cell Proliferation; Cytokines; DNA Damage; Dose-Response Relationship, Drug; Female; Hyperplasia; Immunity, Cellular; Peroxidase; Random Allocation; Rats, Inbred Lew; Resveratrol; Stilbenes; Synovial Membrane | 2016 |
Methylation Landscape of Human Breast Cancer Cells in Response to Dietary Compound Resveratrol.
Topics: Anticarcinogenic Agents; Breast Neoplasms; Cell Line, Tumor; CpG Islands; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Resveratrol; Stilbenes | 2016 |
Mechanism of uncoupling protein 2‑mediated myocardial injury in hypothermic preserved rat hearts.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbazoles; Cryopreservation; Male; Mitochondria, Heart; Myocardium; Organ Preservation; Rats; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Uncoupling Protein 2 | 2016 |
A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway.
Topics: Arachis; Dimethylallyltranstransferase; Hemiterpenes; Organophosphorus Compounds; Plant Proteins; Plant Roots; Plastids; Prenylation; Resveratrol; Seeds; Stilbenes; Substrate Specificity; Terpenes | 2016 |
Sirtuin 1-dependent resveratrol cytotoxicity and pro-differentiation activity on breast cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Cycle Checkpoints; Cell Differentiation; Cell Respiration; Electron Transport Complex I; Female; Humans; Male; MCF-7 Cells; Mitochondria, Liver; Neoplastic Stem Cells; Rats, Wistar; Resveratrol; Sirtuin 1; Sirtuin 3; Stilbenes | 2017 |
Epigenomic maintenance through dietary intervention can facilitate DNA repair process to slow down the progress of premature aging.
Topics: Aging; Animals; Curcumin; DNA Damage; DNA Repair; Docosahexaenoic Acids; Epigenesis, Genetic; Genomic Instability; Humans; Longevity; Plant Extracts; Progeria; Rats; Resveratrol; Stilbenes | 2016 |
Resveratrol-Mediated Repression and Reversion of Prostatic Myofibroblast Phenoconversion.
Topics: Apoptosis; Cell Proliferation; Chemokine CXCL12; Dose-Response Relationship, Drug; Humans; Male; Myofibroblasts; Prostate; Resveratrol; Stilbenes; Transcription, Genetic; Transforming Growth Factor beta | 2016 |
Comprehensive two-dimensional liquid chromatography-tandem mass spectrometry for the simultaneous determination of wine polyphenols and target contaminants.
Topics: Antioxidants; Chromatography, Liquid; Food Contamination; Herbicides; Limit of Detection; Methylurea Compounds; Polyphenols; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Wine | 2016 |
P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Drug Interactions; HEK293 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Kidney; Male; Methotrexate; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats, Wistar; Renal Elimination; Resveratrol; Stilbenes | 2016 |
Novel multifunctional pH-sensitive nanoparticles loaded into microbubbles as drug delivery vehicles for enhanced tumor targeting.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Hydrogen-Ion Concentration; Mice; Microbubbles; Molecular Targeted Therapy; Nanoparticles; Neoplasm Transplantation; Neoplasms; Resveratrol; Stilbenes; Treatment Outcome | 2016 |
Tetrahydropyrrolization of Resveratrol and Other Stilbenes Improves Inhibitory Effects on DNA Oxidation.
Topics: Amidines; Antioxidants; Cycloaddition Reaction; DNA Damage; Imines; Kinetics; Organosilicon Compounds; Oxidation-Reduction; Pyrrolidines; Resveratrol; Stilbenes | 2016 |
Resveratrol exerts protective effects on anoxia/reoxygenation injury in cardiomyocytes via miR-34a/Sirt1 signaling pathway.
Topics: Animals; Antioxidants; MicroRNAs; Myocytes, Cardiac; Rats; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Antibacterial and antibiotic-resistance modifying activity of the extracts and compounds from Nauclea pobeguinii against Gram-negative multi-drug resistant phenotypes.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Plant Extracts; Resveratrol; Rubiaceae; Stilbenes | 2016 |
Riboflavin Phototransformation on the Changes of Antioxidant Capacities in Phenolic Compounds.
Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Caffeic Acids; Chlorogenic Acid; Chromans; Coumaric Acids; Curcumin; Light; Molecular Structure; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Propionates; Quercetin; Resveratrol; Riboflavin; Stilbenes; Sulfonic Acids; Vanillic Acid | 2016 |
Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol.
Topics: Administration, Cutaneous; Cosmeceuticals; Drug Combinations; Drug Eruptions; Female; Hexylresorcinol; Humans; Middle Aged; Niacinamide; Resveratrol; Skin Aging; Skin Care; Skin Pigmentation; Stilbenes; Surveys and Questionnaires; Treatment Outcome; Vitamin A | 2016 |
AhR-dependent 2,3,7,8-tetrachlorodibenzo-p-dioxin toxicity in human neuronal cell line SHSY5Y.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Nucleus; Cell Survival; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Neurons; Neurotoxins; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Resveratrol; RNA, Small Interfering; Stilbenes; Time Factors; Transfection | 2016 |
Effect of Resveratrol Administration on the Element Metabolism in the Blood and Brain Tissues of Rats Subjected to Acute Swimming Exercise.
Topics: Animals; Brain; Male; Physical Conditioning, Animal; Rats; Rats, Wistar; Resveratrol; Stilbenes; Swimming; Trace Elements | 2017 |
Biotransformation of Resveratrol: New Prenylated trans-Resveratrol Synthesized by Aspergillus sp. SCSIOW2.
Topics: Animals; Antioxidants; Aspergillus; Biotransformation; Circular Dichroism; Erythrocyte Membrane; Free Radicals; Magnetic Resonance Spectroscopy; Molecular Structure; Rabbits; Resveratrol; Stilbenes | 2016 |
The Effect of Resveratrol and Quercetin Treatment on PPAR Mediated Uncoupling Protein (UCP-) 1, 2, and 3 Expression in Visceral White Adipose Tissue from Metabolic Syndrome Rats.
Topics: Adipose Tissue, White; Animals; Gene Expression Regulation; Insulin; Linoleic Acid; Male; Metabolic Syndrome; Mitochondrial Uncoupling Proteins; Oleic Acid; Peroxisome Proliferator-Activated Receptors; Quercetin; Radioimmunoassay; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Uncoupling Protein 1; Uncoupling Protein 2; Uncoupling Protein 3 | 2016 |
The Neuroprotective Effects of Resveratrol Preconditioning in Transient Global Cerebral Ischemia-Reperfusion in Mice.
Topics: Animals; Apoptosis; Caspase 3; Cell Survival; Disease Models, Animal; Ischemic Attack, Transient; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Reperfusion Injury; Resveratrol; Stilbenes | 2016 |
The Relationship of Oxidation Sensitivity of Red Blood Cells and Carbonic Anhydrase Activity in Stored Human Blood: Effect of Certain Phenolic Compounds.
Topics: Antioxidants; Caffeic Acids; Carbonic Anhydrases; Erythrocytes; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Malondialdehyde; Oxidation-Reduction; Resveratrol; Specimen Handling; Stilbenes; Tannins | 2016 |
Administration of resveratrol enhances cell-cycle arrest followed by apoptosis in DMBA-induced skin carcinogenesis in male Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Cell Cycle Checkpoints; Male; Rats; Rats, Wistar; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
A facile and rapid access to resveratrol derivatives and their radioprotective activity.
Topics: Animals; Apoptosis; Boronic Acids; Catalysis; Gamma Rays; Oxidation-Reduction; Palladium; Radiation-Protective Agents; Rats; Resveratrol; Stilbenes; Structure-Activity Relationship; Styrenes; Thymocytes | 2016 |
A mechanistic study to increase understanding of titanium dioxide nanoparticles-increased plasma glucose in mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Blood Glucose; Insulin Resistance; Male; Metal Nanoparticles; Mice; Reactive Oxygen Species; Resveratrol; Stilbenes; Titanium; Vitamin E | 2016 |
Classical and atypical resistance of cancer cells as a target for resveratrol.
Topics: Antioxidants; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Humans; Pancreatic Neoplasms; Resveratrol; Stilbenes | 2016 |
Dietary resveratrol improves immunity but reduces reproduction of broodstock medaka Oryzias latipes (Temminck & Schlegel).
Topics: Animals; Cell Proliferation; Diet; Female; Immunity, Cellular; Immunologic Factors; Liver; Lymphocytes; Macrophages; Male; Oryzias; Phagocytosis; Prostaglandin-Endoperoxide Synthases; Reproduction; Resveratrol; Sperm Motility; Spleen; Stilbenes | 2017 |
Resveratrol prevents oxidative damage and loss of sperm motility induced by long-term treatment with valproic acid in Wistar rats.
Topics: Animals; Anticonvulsants; Antioxidants; Fertility; Genitalia, Male; Male; Oxidative Stress; Rats, Wistar; Resveratrol; Sperm Motility; Spermatozoa; Stilbenes; Testosterone; Valproic Acid | 2016 |
Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness.
Topics: Animals; Blotting, Western; Cardiovascular Diseases; Diet, High-Fat; Disease Models, Animal; Glucose Tolerance Test; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; Obesity; Pulse Wave Analysis; Random Allocation; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes; Vascular Cell Adhesion Molecule-1; Vascular Stiffness | 2016 |
Resveratrol Reduces the Incidence of Portal Vein System Thrombosis after Splenectomy in a Rat Fibrosis Model.
Topics: Animals; Anticoagulants; Apoptosis; Blood Platelets; Enoxaparin; Fibrinolytic Agents; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Platelet Aggregation; Portal Vein; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Splenectomy; Stilbenes; Venous Thrombosis | 2016 |
SILAC-MS Based Characterization of LPS and Resveratrol Induced Changes in Adipocyte Proteomics - Resveratrol as Ameliorating Factor on LPS Induced Changes.
Topics: Adipocytes; Adipose Tissue; Angiopoietin-Like Protein 3; Angiopoietin-like Proteins; Angiopoietins; Gastrointestinal Microbiome; Gene Expression Regulation; Glycosylation; Humans; Inflammation; Insulin; Insulin Resistance; Lipid Metabolism; Lipogenesis; Lipopolysaccharides; N-Acetylgalactosaminyltransferases; Obesity; Polypeptide N-acetylgalactosaminyltransferase; Proteome; Proteomics; Resveratrol; Stilbenes | 2016 |
Live fast, die young.
Topics: Africa; Aging; Alzheimer Disease; Amyloid; Animal Feed; Animal Husbandry; Animals; Animals, Laboratory; Breeding; Caloric Restriction; CRISPR-Cas Systems; Crosses, Genetic; Disease Models, Animal; Female; Fundulidae; Genetic Engineering; Genomics; Iron; Life Cycle Stages; Longevity; Male; Mice; Models, Animal; Neurosciences; Resveratrol; Stilbenes; Time Factors | 2016 |
Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol.
Topics: Anti-Inflammatory Agents, Non-Steroidal; CD4-Positive T-Lymphocytes; Cell Line; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Human T-lymphotropic virus 1; Humans; Interleukin-17; Interleukin-1alpha; Interleukin-6; NF-kappa B; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Size Selective Green Synthesis of Silver and Gold Nanoparticles: Enhanced Antibacterial Efficacy of Resveratrol Capped Silver Sol.
Topics: Anti-Bacterial Agents; Escherichia coli; Gold; Metal Nanoparticles; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Resveratrol; Silver; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Stilbenes; X-Ray Diffraction | 2016 |
Effects of resveratrol on carbon monoxide-induced cardiotoxicity in rats.
Topics: Animals; Carbon Monoxide; Carbon Monoxide Poisoning; Carboxyhemoglobin; Cardiotonic Agents; Cardiotoxicity; Caspase 3; Dose-Response Relationship, Drug; Electrocardiography; Heart; Male; Myocardium; Proto-Oncogene Proteins c-akt; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Inhibition of Cardiomyocytes Hypertrophy by Resveratrol Is Associated with Amelioration of Endoplasmic Reticulum Stress.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Atrial Natriuretic Factor; bcl-2-Associated X Protein; Blotting, Western; Cardiomegaly; Cardiotonic Agents; Cell Size; Cells, Cultured; Endoplasmic Reticulum Stress; Gene Expression; Heat-Shock Proteins; Isoproterenol; Microscopy, Electron, Transmission; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Stilbenes | 2016 |
Effect of resveratrol and rosuvastatin on experimental diabetic nephropathy in rats.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression Regulation; Glycated Hemoglobin; Kidney; Male; Nerve Tissue Proteins; NF-kappa B; Oxidative Stress; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Rosuvastatin Calcium; Sirtuin 1; Stilbenes; Transforming Growth Factor beta1 | 2016 |
SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis.
Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Experimental; Gene Silencing; Glucose; Humans; Hyperglycemia; Kidney Tubules, Proximal; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Streptozocin | 2016 |
Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice.
Topics: Animals; Bacteria; Blood Glucose; Clostridium; Diet, High-Fat; Gastrointestinal Microbiome; Glucose Intolerance; Glucose Tolerance Test; Insulin; Intestines; Lactococcus; Male; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Obesity; Resveratrol; Signal Transduction; Sirolimus; Stilbenes | 2016 |
Piceatannol and resveratrol share inhibitory effects on hydrogen peroxide release, monoamine oxidase and lipogenic activities in adipose tissue, but differ in their antilipolytic properties.
Topics: Adipocytes; Adult; Animals; Benzylamines; Biocatalysis; Catalase; Electron Spin Resonance Spectroscopy; Female; Humans; Hydrogen Peroxide; Lipogenesis; Lipolysis; Mice, Inbred C57BL; Molecular Docking Simulation; Monoamine Oxidase; Oxidants; Resveratrol; Stilbenes; Subcutaneous Fat; Tyramine | 2016 |
Resveratrol affects DNA damage induced by ionizing radiation in human lymphocytes in vitro.
Topics: Apoptosis; Cell Cycle; DNA Damage; Flow Cytometry; Humans; Lymphocytes; Radiation, Ionizing; Resveratrol; Stilbenes | 2016 |
Beneficial effects of combined resveratrol and metformin therapy in treating diet-induced insulin resistance.
Topics: Adiposity; Animals; Blood Glucose; Diet, High-Fat; Drug Therapy, Combination; Inflammation Mediators; Insulin Resistance; Male; Metformin; Mice; Mice, Inbred C57BL; Oncogene Protein v-akt; Organ Specificity; Resveratrol; Stilbenes | 2016 |
Resveratrol, a natural antioxidant, protects monosodium iodoacetate-induced osteoarthritic pain in rats.
Topics: Animals; Antioxidants; Cartilage, Articular; Cyclooxygenase 2; Cytokines; Extremities; Hyperalgesia; Iodoacetates; Male; Nitric Oxide Synthase Type II; Osteoarthritis; Pain; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Synovial Fluid | 2016 |
Preventive effects of Resveratrol against azoxymethane-induced testis injury in rats.
Topics: Animals; Antioxidants; Azoxymethane; Carcinogens; Male; Oxidative Stress; Rats; Resveratrol; Seminiferous Tubules; Stilbenes; Testis; Testosterone | 2017 |
Resveratrol inhibits phosphorylation within the signal transduction and activator of transcription 3 signaling pathway by activating sirtuin 1 in SW1353 chondrosarcoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Bone Neoplasms; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chondrosarcoma; Dose-Response Relationship, Drug; Humans; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Signal Transduction; Sirtuin 1; STAT3 Transcription Factor; Stilbenes | 2016 |
Resveratrol primes the effects of physical activity in old mice.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle, Skeletal; Physical Conditioning, Animal; Physical Endurance; Resveratrol; Stilbenes | 2016 |
Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Differentiation; Cell Line; Cell Proliferation; Diabetic Nephropathies; Fibroblasts; Fibrosis; Gene Expression Regulation; Glucose; Kidney; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myofibroblasts; NADPH Oxidase 4; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Comment on "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice".
Topics: Adenoma; Animals; Chemoprevention; Diet, High-Fat; Humans; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes | 2016 |
Response to comment on "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice".
Topics: Adenoma; Animals; Antioxidants; Carcinogenesis; Chemoprevention; Colorectal Neoplasms; Diet, High-Fat; Female; Humans; Male; Mice; Resveratrol; Stilbenes | 2016 |
The protective effect of resveratrol against cytotoxicity induced by mycotoxin, zearalenone.
Topics: Acetylation; Apoptosis; Cell Cycle Checkpoints; Cell Survival; Edible Grain; Food Contamination; Forkhead Box Protein O3; Gene Expression; HEK293 Cells; Humans; Lipid Peroxidation; Malondialdehyde; Membrane Potential, Mitochondrial; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase; Zearalenone | 2016 |
CSTMP induces apoptosis and mitochondrial dysfunction in human myeloma RPMI8226 cells via CHOP-dependent endoplasmic reticulum stress.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Mitochondria; Multiple Myeloma; Pyrazines; Resveratrol; Stilbenes; Transcription Factor CHOP; Unfolded Protein Response | 2016 |
Bioconversion of piceid to resveratrol by selected probiotic cell extracts.
Topics: Glucosides; Gram-Positive Bacteria; Resveratrol; Stilbenes | 2016 |
The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Movement; Cell Survival; Enzyme-Linked Immunosorbent Assay; Female; Hypoxia; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Microscopy, Fluorescence; Naphthols; Neoplastic Stem Cells; Neovascularization, Pathologic; Radiation Tolerance; Radiation-Sensitizing Agents; Real-Time Polymerase Chain Reaction; Resorcinols; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
Resveratrol induces thermal stabilization of human serum albumin and modulates the early aggregation stage.
Topics: Binding Sites; Hot Temperature; Humans; Kinetics; Protein Aggregates; Protein Binding; Protein Domains; Protein Stability; Protein Structure, Secondary; Protein Unfolding; Resveratrol; Serum Albumin; Stilbenes; Thermodynamics | 2016 |
Grape compounds suppress colon cancer stem cells in vitro and in a rodent model of colon carcinogenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Grape Seed Extract; Male; Mice; Neoplastic Stem Cells; Resveratrol; Signal Transduction; Stilbenes; Vitis | 2016 |
Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay.
Topics: Antiviral Agents; Dengue Virus; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Microbial Sensitivity Tests; Protein Biosynthesis; Resveratrol; Stilbenes; Virus Replication | 2017 |
Resveratrol Treatment Prevents Hippocampal Neurodegeneration in a Rodent Model of Traumatic Brain Injury.
Topics: Animals; Antioxidants; Brain Injuries, Traumatic; DNA Damage; Glutathione Peroxidase; Hippocampus; Male; Malondialdehyde; Nerve Degeneration; Neuroprotective Agents; Rats; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
Effects of resveratrol on the alterations of cavernosal eNOS and LOX-1 expression in the hypercholesterolemic condition: a preliminary study.
Topics: Animals; Erectile Dysfunction; Hypercholesterolemia; Male; Nitric Oxide Synthase Type III; Penis; Rabbits; Resveratrol; Scavenger Receptors, Class E; Stilbenes | 2016 |
Effects of resveratrol and cigarette smoking onbone healing: histomorphometric evaluation.
Topics: Animals; Cigarette Smoking; Rats; Rats, Sprague-Dawley; Resveratrol; Smoke; Stilbenes | 2016 |
Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress.
Topics: Antioxidants; Ethanol; Fibroblasts; Gene Expression Regulation; Glutathione; HeLa Cells; Hep G2 Cells; Hormesis; HT29 Cells; Humans; Keratinocytes; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Primary Cell Culture; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis.
Topics: Animals; Antioxidants; Behavior, Animal; Cell Proliferation; Dentate Gyrus; Depression; Dimethyl Sulfoxide; Disease Models, Animal; Ependymoglial Cells; Hippocampus; Humans; Immunohistochemistry; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Neurogenesis; NF-kappa B; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Stress, Psychological; Transcription Factor HES-1; Up-Regulation | 2016 |
Improving solubility, stability, and cellular uptake of resveratrol by nanoencapsulation with chitosan and γ-poly (glutamic acid).
Topics: Antioxidants; Biological Availability; Caco-2 Cells; Cell Proliferation; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Stability; Humans; Nanoparticles; Polyglutamic Acid; Resveratrol; Solubility; Stilbenes | 2016 |
Sirtuin 3 Deregulation Promotes Pulmonary Fibrosis.
Topics: Aging; Animals; Cell Differentiation; Disease Models, Animal; Down-Regulation; Fibroblasts; Humans; Isocitrate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pulmonary Fibrosis; Resveratrol; Sirtuin 3; Smad3 Protein; Stilbenes; Superoxide Dismutase; Transforming Growth Factor beta1 | 2017 |
Effect of resveratrol and environmental enrichment on biomarkers of oxidative stress in young healthy mice.
Topics: Animals; Antioxidants; Biomarkers; Brain; Environment; Glutathione Peroxidase; Housing, Animal; Lipid Peroxidation; Malondialdehyde; Mice; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
Xanthine Oxidase-Derived ROS Display a Biphasic Effect on Endothelial Cells Adhesion and FAK Phosphorylation.
Topics: Androstadienes; Cell Adhesion; Focal Adhesion Protein-Tyrosine Kinases; Human Umbilical Vein Endothelial Cells; Humans; Hypoxanthine; Immunoprecipitation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Reactive Oxygen Species; Resveratrol; Stilbenes; Wortmannin; Xanthine Oxidase | 2016 |
Resveratrol Attenuates Acute Inflammatory Injury in Experimental Subarachnoid Hemorrhage in Rats via Inhibition of TLR4 Pathway.
Topics: Animals; Anti-Inflammatory Agents; Brain; Inflammation; Male; Myeloid Differentiation Factor 88; NF-kappa B; Rats; Resveratrol; Signal Transduction; Stilbenes; Subarachnoid Hemorrhage; Toll-Like Receptor 4 | 2016 |
Inhibition of cytochrome P450 3A by acetoxylated analogues of resveratrol in in vitro and in silico models.
Topics: Animals; Binding Sites; Cell Line; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Microsomes, Liver; Models, Chemical; Molecular Docking Simulation; Rats; Resveratrol; Static Electricity; Stilbenes; Testosterone | 2016 |
Resveratrol defends blood-brain barrier integrity in experimental autoimmune encephalomyelitis mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Inflammation Mediators; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes | 2016 |
Fluorometric Investigation on the Binding of Letrozole and Resveratrol with Serum Albumin.
Topics: Aromatase Inhibitors; Fluorometry; Humans; Letrozole; Nitriles; Protein Binding; Resveratrol; Serum Albumin; Spectrometry, Fluorescence; Stilbenes; Triazoles | 2016 |
Hydrogen sulfide: A novel mechanism for the vascular protection by resveratrol under oxidative stress in mouse aorta.
Topics: Animals; Antioxidants; Aorta; Cysteine; Hydrogen Sulfide; Male; Mice; Nitric Oxide; Oxidative Stress; Pyrogallol; Reactive Oxygen Species; Resveratrol; Stilbenes | 2016 |
In vitro comparative studies of resveratrol and triacetylresveratrol on cell proliferation, apoptosis, and STAT3 and NFκB signaling in pancreatic cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Neoplasm Proteins; NF-kappa B; Pancreatic Neoplasms; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2016 |
A steroid like phytochemical Antcin M is an anti-aging reagent that eliminates hyperglycemia-accelerated premature senescence in dermal fibroblasts by direct activation of Nrf2 and SIRT-1.
Topics: Acetylcysteine; Antioxidants; Antrodia; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Cellular Senescence; Cholestenones; Endothelial Cells; Fibroblasts; Gene Silencing; Glucose; Humans; Hyperglycemia; Medicine, Chinese Traditional; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Phytochemicals; Reactive Oxygen Species; Resveratrol; Retinoblastoma Protein; Sirtuin 1; Skin; Stilbenes; Triterpenes | 2016 |
TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy.
Topics: Acetylation; Animals; Autophagy; Carbazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; Histone Deacetylase Inhibitors; Humans; Lysine; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Niacinamide; Protein Domains; Protein Processing, Post-Translational; Protein Stability; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; TOR Serine-Threonine Kinases; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2016 |
Resveratrol intake enhances indoleamine-2,3-dioxygenase activity in humans.
Topics: Administration, Oral; Adult; Biomarkers; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Neopterin; Pilot Projects; Resveratrol; Stilbenes; Tryptophan; Young Adult | 2016 |
Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells.
Topics: Antigens, CD; CD83 Antigen; Cell Differentiation; Dendritic Cells; Drug Carriers; Flow Cytometry; Fluorescein-5-isothiocyanate; Humans; Immune Tolerance; Immunoglobulins; Interleukin-12; Lipids; Membrane Glycoproteins; Monocytes; Nanostructures; NF-kappa B; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol improves TNF-α-induced endothelial dysfunction in a coculture model of a Caco-2 with an endothelial cell line.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Caco-2 Cells; Cell Communication; Cell Line; Coculture Techniques; Endothelium, Vascular; Enterocytes; Glucuronides; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-8; Intestinal Absorption; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Sulfates; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factors | 2016 |
Resveratrol inhibits steroidogenesis in human fetal adrenocortical cells at the end of first trimester.
Topics: Adrenal Cortex; Cells, Cultured; Cytochrome P450 Family 21; Female; Humans; Pregnancy; Pregnancy Trimester, First; Resveratrol; Steroid 17-alpha-Hydroxylase; Steroids; Stilbenes | 2017 |
Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic plasticity.
Topics: Animals; Antioxidants; Blood Glucose; Cognition; Cognition Disorders; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus, Experimental; Hippocampus; Inflammation; Male; Maze Learning; Memory; Neuronal Plasticity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase; Synapses | 2016 |
Fabrication of an ionic-sensitive in situ gel loaded with resveratrol nanosuspensions intended for direct nose-to-brain delivery.
Topics: Administration, Intranasal; Animals; Antioxidants; Biological Availability; Biological Transport; Brain; Drug Carriers; Drug Delivery Systems; Gels; Mice; Nanoparticles; Nasal Mucosa; Resveratrol; Stilbenes; Suspensions; Tissue Distribution; Viscosity | 2016 |
Long-term treatment with nicotinamide induces glucose intolerance and skeletal muscle lipotoxicity in normal chow-fed mice: compared to diet-induced obesity.
Topics: Animals; Antioxidants; Autophagy; Diet, High-Fat; Dietary Supplements; Gene Expression Regulation; Glucose Intolerance; Histone Deacetylase Inhibitors; Insulin Resistance; Lipid Metabolism; Male; Mice, Inbred C57BL; Mitophagy; Muscle Proteins; Muscle, Skeletal; Niacinamide; Obesity; Resveratrol; Sirtuin 1; Stilbenes; Time Factors | 2016 |
Evaluate the ability of PVP to inhibit crystallization of amorphous solid dispersions by density functional theory and experimental verify.
Topics: Calorimetry, Differential Scanning; Crystallization; Drug Liberation; Griseofulvin; Hydrogen Bonding; Povidone; Powder Diffraction; Resveratrol; Solubility; Spectroscopy, Fourier Transform Infrared; Stilbenes; X-Ray Diffraction | 2017 |
Resveratrol pretreatment attenuates injury and promotes proliferation of neural stem cells following oxygen-glucose deprivation/reoxygenation by upregulating the expression of Nrf2, HO-1 and NQO1 in vitro.
Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Cells, Cultured; Female; Glucose; Heme Oxygenase-1; Male; NAD(P)H Dehydrogenase (Quinone); Neural Stem Cells; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Oxygen; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol Protects Rabbits Against Cholesterol Diet-Induced Hyperlipidaemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Hyperlipidemias; Male; Protective Agents; Rabbits; Resveratrol; Stilbenes; Triglycerides | 2016 |
Stilbene biosynthesis in the needles of spruce Picea jezoensis.
Topics: Acyltransferases; Glucosides; Phenols; Picea; Plant Bark; Plant Roots; Resveratrol; Stilbenes | 2016 |
High Mobility Group Box 1 Mediates Interferon-γ-Induced Phenotypic Modulation of Vascular Smooth Muscle Cells.
Topics: Animals; Gene Expression Regulation, Enzymologic; HMGB1 Protein; Interferon-gamma; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Sirtuin 1 and 7 mediate resveratrol-induced recovery from hyper-anxiety in high-fructose-fed prediabetic rats.
Topics: Animals; Antioxidants; Anxiety Disorders; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet; Epigenesis, Genetic; Fructose; Gene Expression Regulation; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Metformin; Prediabetic State; Rats; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2016 |
Resveratrol Protects against High-Fat Diet Induced Renal Pathological Damage and Cell Senescence by Activating SIRT1.
Topics: Animals; Cellular Senescence; Diet, High-Fat; Kidney; Male; Mice, Inbred C57BL; Protective Agents; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
3'-hydroxy-3,4,5,4'-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Genome, Human; Humans; Metabolome; Mice; Mice, SCID; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2016 |
Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington's Disease Models.
Topics: Animals; Corpus Striatum; Disease Models, Animal; DNA, Mitochondrial; Humans; Huntington Disease; Membrane Potential, Mitochondrial; Mice, Transgenic; Mitochondria; Neurons; Niacinamide; Resveratrol; Stilbenes | 2017 |
Therapeutic Effects of Resveratrol in a Mouse Model of LPS and Cigarette Smoke-Induced COPD.
Topics: Animals; Beclin-1; Bronchoalveolar Lavage Fluid; Cytokines; Lipopolysaccharides; Lung; Mice; Mucus; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Resveratrol; Smoke; Stilbenes | 2016 |
Identification of resveratrol derivative 3,3',4,4',5,5'-hexamethoxy- trans-stilbene as a novel pro-angiogenic small-molecule compound.
Topics: Animals; Cell Movement; Cell Proliferation; Drug Evaluation, Preclinical; Early Growth Response Protein 1; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Resveratrol; Stilbenes; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2016 |
Differential inhibition of human erythrocyte acetylcholinesterase by polyphenols epigallocatechin-3-gallate and resveratrol. Relevance of the membrane-bound form.
Topics: Acetylcholinesterase; Catechin; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Erythrocyte Membrane; Humans; Inhibitory Concentration 50; Resveratrol; Stilbenes | 2017 |
Cisplatin and resveratrol induce apoptosis and autophagy following oxidative stress in malignant mesothelioma cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Caspase 3; Cisplatin; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Oxidative Stress; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
The protective effects of resveratrol on social stress-induced cytokine release and depressive-like behavior.
Topics: Adaptation, Psychological; Anhedonia; Animals; Antioxidants; Cytokines; Depressive Disorder; Dose-Response Relationship, Drug; Locus Coeruleus; Male; Raphe Nuclei; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Resveratrol; Social Environment; Spleen; Stilbenes; Stress, Psychological | 2017 |
Ability of resveratrol to inhibit advanced glycation end product formation and carbohydrate-hydrolyzing enzyme activity, and to conjugate methylglyoxal.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Antioxidants; Carbohydrates; Cattle; Glycation End Products, Advanced; Glycosylation; Hydrolysis; Pyruvaldehyde; Resveratrol; Serum Albumin, Bovine; Stilbenes | 2017 |
Resveratrol lacks protective activity against acute seizures in mouse models.
Topics: Animals; Anticonvulsants; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Pentylenetetrazole; Resveratrol; Seizures; Stilbenes; Treatment Failure | 2016 |
Resveratrol ameliorates spatial learning memory impairment induced by Aβ
Topics: Amyloid beta-Peptides; Animals; Blotting, Western; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Learning Disabilities; Long-Term Potentiation; Male; Memory Disorders; Neuroprotective Agents; Nootropic Agents; Peptide Fragments; Phosphorylation; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Spatial Learning; Spatial Memory; Stilbenes; Time Factors | 2017 |
Resveratrol attenuates acute kidney injury by inhibiting death receptor‑mediated apoptotic pathways in a cisplatin‑induced rat model.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cisplatin; Kidney; Male; Protective Agents; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Calcium; Calcium Channels; Calcium-Binding Proteins; Caspase 3; Caspase 7; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Ion Transport; Membrane Proteins; Mitochondria; Organ Specificity; Resveratrol; RNA, Small Interfering; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stilbenes | 2016 |
Potential protective effect of resveratrol on acoustic trauma: electron microscopy study.
Topics: Animals; Cochlea; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Microscopy, Electron, Scanning; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2016 |
Effect of quercetin and resveratrol co-incorporated in liposomes against inflammatory/oxidative response associated with skin cancer.
Topics: Administration, Topical; Animals; Antioxidants; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Dynamic Light Scattering; Female; Fibroblasts; Humans; Inflammation; Liposomes; Mice; Oxidative Stress; Quercetin; Reactive Oxygen Species; Resveratrol; Skin Neoplasms; Stilbenes | 2016 |
Autophagy and mitochondrial dysfunction in adjuvant-arthritis rats treatment with resveratrol.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Autophagy; Cells, Cultured; Mitochondria; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Synoviocytes | 2016 |
ATM/CHK/p53 Pathway Dependent Chemopreventive and Therapeutic Activity on Lung Cancer by Pterostilbene.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia Mutated Proteins; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Humans; Lung Neoplasms; Proteome; Respiratory Mucosa; Resveratrol; Rheum; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2016 |
Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver.
Topics: AMP-Activated Protein Kinases; Animals; Cytokines; Humans; Mice; NF-kappa B; Non-alcoholic Fatty Liver Disease; Phosphorylation; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2016 |
Resveratrol cross-linked chitosan loaded with phospholipid for controlled release and antioxidant activity.
Topics: Animals; Antioxidants; Chitosan; Delayed-Action Preparations; Mice; NIH 3T3 Cells; Phospholipids; Resveratrol; Stilbenes | 2016 |
Arbuscular mycorrhizal symbiosis stimulates key genes of the phenylpropanoid biosynthesis and stilbenoid production in grapevine leaves in response to downy mildew and grey mould infection.
Topics: Benzofurans; Botrytis; Oomycetes; Phenylpropionates; Plant Components, Aerial; Plant Diseases; Plant Leaves; Resorcinols; Resveratrol; Stilbenes; Symbiosis; Vitis | 2016 |
Resveratrol Ameliorates Alcoholic Fatty Liver by Inducing Autophagy.
Topics: Animals; Autophagy; Disease Models, Animal; Fatty Liver, Alcoholic; Hep G2 Cells; Hepatocytes; Humans; Lipid Droplets; Male; Mice, Inbred C57BL; Phytotherapy; Resveratrol; Stilbenes; Vitis; Wine | 2016 |
Resveratrol ameliorates LPS-induced acute lung injury via NLRP3 inflammasome modulation.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Inflammasomes; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Random Allocation; Resveratrol; Stilbenes | 2016 |
Convergent Effects of Resveratrol and PYK2 on Prostate Cells.
Topics: Antioxidants; Autophagy; Cell Line; Cell Proliferation; Cell Size; Focal Adhesion Kinase 2; Gene Expression Regulation; Humans; Male; Mutation; Oxidative Stress; Prostate; Resveratrol; Stilbenes | 2016 |
Protective effects of resveratrol and its analogs on age-related macular degeneration in vitro.
Topics: Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Macular Degeneration; Neuroprotective Agents; Resveratrol; Retinal Pigment Epithelium; Stilbenes | 2016 |
Resveratrol attenuates myocardial ischemia/reperfusion injury through up-regulation of vascular endothelial growth factor B.
Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Cell Line; Creatine Kinase, MB Form; Gene Expression Regulation; Glycogen Synthase Kinase 3 beta; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Organ Culture Techniques; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Superoxide Dismutase; Vascular Endothelial Growth Factor B; Ventricular Function, Left | 2016 |
YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Enzyme Inhibitors; Gemcitabine; Gene Expression Regulation, Enzymologic; Humans; Pancreatic Neoplasms; Phosphoproteins; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Transcription Factors; YAP-Signaling Proteins | 2016 |
Resveratrol promotes myenteric neuroprotection in the ileum of rats after ischemia-reperfusion injury.
Topics: Animals; Antioxidants; Cell Proliferation; Ileum; Male; Myenteric Plexus; Neuroglia; Neurons; Neuroprotection; Neuroprotective Agents; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2016 |
Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans.
Topics: Acetylcysteine; Aging; Animals; Antioxidants; Ascorbic Acid; Caenorhabditis elegans; Longevity; Mitochondria; Models, Biological; Mutation; Oxidative Stress; Paraquat; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
Effects of Trans-Resveratrol on hyperglycemia-induced abnormal spermatogenesis, DNA damage and alterations in poly (ADP-ribose) polymerase signaling in rat testis.
Topics: Animals; Diabetes Mellitus, Type 1; DNA Damage; Hyperglycemia; Male; Oxidation-Reduction; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Spermatogenesis; Spermatozoa; Stilbenes; Testis | 2016 |
Development of resveratrol-curcumin hybrids as potential therapeutic agents for inflammatory lung diseases.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Curcumin; Gene Expression Regulation; Humans; Interleukin-6; Lung; Mice; RAW 264.7 Cells; Resveratrol; RNA, Messenger; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol induces chain interdigitation in DPPC cell membrane model systems.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biophysical Phenomena; Calorimetry, Differential Scanning; Cell Membrane; Electron Spin Resonance Spectroscopy; Gels; Lipid Bilayers; Liquid Crystals; Membrane Lipids; Molecular Docking Simulation; Phase Transition; Resveratrol; Stilbenes; Transition Temperature; X-Ray Diffraction | 2016 |
Systematical investigation of a combinative particle size reduction technology for production of resveratrol nanosuspensions.
Topics: Nanoparticles; Particle Size; Resveratrol; Stilbenes; Surface-Active Agents; Suspensions; Technology, Pharmaceutical | 2017 |
Nanocarriers enhance the transdermal bioavailability of resveratrol: In-vitro and in-vivo study.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Drug Carriers; Drug Stability; Emulsions; Nanostructures; Particle Size; Rats, Sprague-Dawley; Resveratrol; Skin; Skin Absorption; Skin Tests; Stilbenes; Thermodynamics; Viscosity | 2016 |
Metformin potentiates anti-tumor effect of resveratrol on pancreatic cancer by down-regulation of VEGF-B signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Synergism; Humans; Hypoglycemic Agents; Metformin; Mice, Nude; Pancreatic Neoplasms; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Vascular Endothelial Growth Factor B; Xenograft Model Antitumor Assays | 2016 |
Anti-Campylobacter activity of resveratrol and an extract from waste Pinot noir grape skins and seeds, and resistance of Camp. jejuni planktonic and biofilm cells, mediated via the CmeABC efflux pump.
Topics: Animals; ATP-Binding Cassette Transporters; Bacterial Adhesion; Bacterial Proteins; Biofilms; Campylobacter jejuni; Cell Line; Drug Resistance, Bacterial; Epithelial Cells; Humans; Intestines; Microbial Sensitivity Tests; Plankton; Polystyrenes; Resveratrol; Seeds; Stilbenes; Swine; Vitis | 2017 |
Piceatannol is superior to resveratrol in promoting neural stem cell differentiation into astrocytes.
Topics: Animals; Astrocytes; Cell Differentiation; Gene Expression Regulation; Hippocampus; Male; Mice; Molecular Structure; Neural Stem Cells; Resveratrol; Stilbenes | 2016 |
The role of expression imbalance between adipose synthesis and storage mediated by PPAR-γ/FSP27 in the formation of insulin resistance in catch up growth.
Topics: Adipocytes; Adipose Tissue; Animals; Apoptosis Regulatory Proteins; Caloric Restriction; Energy Intake; Epididymis; Epididymitis; Gene Expression Regulation; Humans; Insulin Resistance; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Proteins; Rats; Resveratrol; Stilbenes; Subcutaneous Fat | 2016 |
Lumbar puncture-administered resveratrol inhibits STAT3 activation, enhancing autophagy and apoptosis in orthotopic rat glioblastomas.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Magnetic Resonance Imaging; Rats; Resveratrol; Signal Transduction; Spinal Puncture; STAT3 Transcription Factor; Stilbenes | 2016 |
Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Resveratrol; Stilbenes | 2016 |
The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis.
Topics: Animals; Cell Cycle; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; HeLa Cells; Humans; Mitosis; Neoplasms; Resveratrol; Stilbenes; Tubulin | 2017 |
Resveratrol Attenuates Copper and Zinc Homeostasis and Ameliorates Oxidative Stress in Type 2 Diabetic Rats.
Topics: Administration, Oral; Animals; Copper; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Homeostasis; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Zinc | 2017 |
A Novel Resveratrol Based Tubulin Inhibitor Induces Mitotic Arrest and Activates Apoptosis in Cancer Cells.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzene Derivatives; Cell Line, Tumor; Cells, Cultured; G2 Phase Cell Cycle Checkpoints; HEK293 Cells; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mitosis; Neoplasms; Neoplasms, Experimental; Polymerization; Resveratrol; Stilbenes; Tubulin; Tubulin Modulators | 2016 |
Protective effect of resveratrol on spermatozoa function in male infertility induced by excess weight and obesity.
Topics: Acrosin; Adult; Cell Survival; Cytoplasm; Gonadal Steroid Hormones; Humans; Infertility, Male; Male; Obesity; Overweight; Protective Agents; Resveratrol; Semen Analysis; Spermatozoa; Stilbenes; Zinc | 2016 |
Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces apoptosis via Fas-mediated pathway in HL-60 human leukemia cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Cytochromes c; Fas Ligand Protein; HL-60 Cells; Humans; Membrane Potential, Mitochondrial; Oligopeptides; Poly(ADP-ribose) Polymerases; Quinazolines; Resveratrol; Stilbenes | 2016 |
Resveratrol Ameliorates the Depressive-Like Behaviors and Metabolic Abnormalities Induced by Chronic Corticosterone Injection.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Body Weight; Corticosterone; Depression; Disease Models, Animal; Drug Administration Schedule; Fluoxetine; Lipids; Male; Mice; Mice, Inbred ICR; Pioglitazone; Resveratrol; Stilbenes; Swimming; Thiazolidinediones | 2016 |
Synthesis, oxygen radical absorbance capacity, and tyrosinase inhibitory activity of glycosides of resveratrol, pterostilbene, and pinostilbene.
Topics: Agaricales; Biocatalysis; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Glucosyltransferases; Glycosides; Glycosylation; Monophenol Monooxygenase; Oxygen Radical Absorbance Capacity; Resveratrol; Stilbenes | 2017 |
Diet-induced non-alcoholic fatty liver disease affects expression of major cytochrome P450 genes in a mouse model.
Topics: Animals; Cytochrome P-450 Enzyme System; Diet, High-Fat; Dietary Sucrose; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Isoenzymes; Lipids; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Resveratrol; RNA, Messenger; Stilbenes; Time Factors | 2016 |
Resveratrol induces mitochondrial respiration and apoptosis in SW620 colon cancer cells.
Topics: Adenosine Triphosphate; Apoptosis; Caloric Restriction; Cell Line, Tumor; Cell Respiration; Colon; Colonic Neoplasms; Energy Metabolism; Fatty Acids; Glycolysis; Humans; Mitochondria; Mitochondrial Membranes; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Plausible anti-inflammatory mechanism of resveratrol and caffeic acid against chronic stress-induced insulin resistance in mice.
Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Caffeic Acids; Corticosterone; Cytokines; Drug Therapy, Combination; Glyburide; Hypoglycemic Agents; Insulin Resistance; Male; Mice, Inbred Strains; Restraint, Physical; Resveratrol; Stilbenes; Stress, Psychological | 2016 |
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.
Topics: Animals; Antioxidants; Blotting, Western; Chagas Cardiomyopathy; Disease Models, Animal; Heart; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcriptome; Trypanosoma cruzi | 2016 |
Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach.
Topics: Animals; Cattle; Culture Media; Glycosylation; Humans; Hydroxylation; Oxidation-Reduction; Polyphenols; Resveratrol; Serum; Stilbenes | 2017 |
Resveratrol, piperine and apigenin differ in their NADPH-oxidase inhibitory and reactive oxygen species-scavenging properties.
Topics: Alkaloids; Antioxidants; Apigenin; Benzodioxoles; Cell Line; Humans; Hydrogen Peroxide; NADP; NADPH Oxidases; Oxidation-Reduction; Pentacyclic Triterpenes; Piperidines; Plant Extracts; Polyunsaturated Alkamides; Reactive Oxygen Species; Resveratrol; Stilbenes; Triterpenes | 2016 |
Selectivity mapping of the binding sites of (E)-resveratrol imprinted polymers using structurally diverse polyphenolic compounds present in Pinot noir grape skins.
Topics: Binding Sites; Chromatography, High Pressure Liquid; Fruit; Molecular Imprinting; Plant Extracts; Polymers; Polyphenols; Porosity; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Surface Properties; Tandem Mass Spectrometry; Vitis | 2016 |
Protective effect of resveratrol against nigrostriatal pathway injury in striatum via JNK pathway.
Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Corpus Striatum; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Neural Pathways; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Random Allocation; Resveratrol; Stilbenes; Substantia Nigra | 2017 |
Curcumin Shows Antiviral Properties against Norovirus.
Topics: Animals; Antiviral Agents; Caliciviridae Infections; Cell Line; Curcumin; Dose-Response Relationship, Drug; Humans; Mice; Models, Biological; Norovirus; RAW 264.7 Cells; Resveratrol; Stilbenes; Virus Internalization; Virus Replication | 2016 |
Resveratrol alleviates sepsis‑induced myocardial injury in rats by suppressing neutrophil accumulation, the induction of TNF‑α and myocardial apoptosis via activation of Sirt1.
Topics: Animals; Apoptosis; Cardiomyopathies; Disease Models, Animal; Male; Neutrophil Infiltration; Neutrophils; Rats; Resveratrol; Sepsis; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol induces cell cycle arrest and apoptosis in human eosinophils from asthmatic individuals.
Topics: Adult; Apoptosis; Asthma; Cell Cycle Checkpoints; Cell Proliferation; Cells, Cultured; Eosinophils; Female; Humans; Male; Resveratrol; Stilbenes; Young Adult | 2016 |
Dose-dependent short- and long-term effects of ionizing irradiation on neural stem cells in murine hippocampal tissue cultures: neuroprotective potential of resveratrol.
Topics: Animals; Cell Death; Cell Proliferation; Dose-Response Relationship, Radiation; Drug Evaluation, Preclinical; Hippocampus; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Nestin; Neural Stem Cells; Neuroglia; Neurons; Neuroprotective Agents; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation, Ionizing; Resveratrol; Stilbenes; Time Factors; Tissue Culture Techniques; X-Rays | 2016 |
Resveratrol alleviates ethanol-induced hormonal and metabolic disturbances in the rat.
Topics: Adiponectin; Animals; Ethanol; Fatty Acids, Nonesterified; Glucagon; Insulin; Lipid Metabolism; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Triglycerides | 2017 |
Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein.
Topics: Acetylation; Administration, Oral; Antineoplastic Agents; Apoptosis; Biological Availability; Caffeic Acids; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lysine; Molecular Docking Simulation; Molecular Targeted Therapy; Phosphorylation; Protein Conformation; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2016 |
Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy.
Topics: Autophagy; Beclin-1; Cell Line, Tumor; Cell Movement; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Ovarian Neoplasms; Resveratrol; rho GTP-Binding Proteins; Stilbenes; Up-Regulation | 2017 |
Resveratrol Interaction with Lipid Bilayers: A Synchrotron X-ray Scattering Study.
Topics: Animals; Cattle; Cholesterol; Egg Yolk; Lipid Bilayers; Phosphatidylcholines; Resveratrol; Scattering, Small Angle; Sheep; Sphingomyelins; Stilbenes; Synchrotrons; X-Ray Diffraction | 2016 |
Resveratrol Reverses Functional Chagas Heart Disease in Mice.
Topics: Animals; Antioxidants; Chagas Cardiomyopathy; Cyclic N-Oxides; Disease Models, Animal; Female; Male; Metformin; Mice; Mice, Inbred BALB C; Oxidative Stress; Resveratrol; Spin Labels; Stilbenes | 2016 |
Comparison of Regulation Mechanisms of Five Mulberry Ingredients on Insulin Secretion under Oxidative Stress.
Topics: Animals; Anthocyanins; Apoptosis; Cell Line; Glucokinase; Glucosides; Homeodomain Proteins; Insulin; Insulin-Secreting Cells; Mice; Morus; Oxidative Stress; Paclitaxel; Plant Extracts; Resveratrol; Signal Transduction; Stilbenes; Trans-Activators | 2016 |
Resveratrol changes spermatogonial stem cells (SSCs) activity and ameliorates their loss in busulfan-induced infertile mouse.
Topics: Adult Germline Stem Cells; Animals; Apoptosis; Azoospermia; Busulfan; Cell Line; Cell Proliferation; Cell Survival; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Fertility; Male; Mice, Inbred ICR; Resveratrol; Spermatogenesis; Stilbenes; Time Factors | 2016 |
Design, synthesis and antibreast cancer MCF-7 cells biological evaluation of heterocyclic analogs of resveratrol.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Models, Molecular; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2017 |
A Prospective Experimental Study on the Protective Effect of Resveratrol against Amikacin-Induced Ototoxicity in Rats.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Antioxidants; Disease Models, Animal; Female; Hearing Loss; Otoacoustic Emissions, Spontaneous; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2016 |
Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia.
Topics: Animals; Animals, Newborn; bcl-2-Associated X Protein; Brain Injuries; Caspase 3; Cytokines; Disease Models, Animal; Gene Expression Regulation; Hypoxia-Ischemia, Brain; Male; Microglia; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Resveratrol; Stilbenes | 2016 |
Combinatorial Treatment Effects in a Cell Culture Model of Alzheimer's Disease.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antipsychotic Agents; Catechin; Cell Line, Tumor; Cytokines; Drug Combinations; Gene Expression Regulation, Neoplastic; Humans; Melatonin; Mice; Mutation; Neuroblastoma; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection | 2017 |
Anti-inflammatory protection afforded by cyanidin-3-glucoside and resveratrol in human intestinal cells via Nrf2 and PPAR-γ: Comparison with 5-aminosalicylic acid.
Topics: Anthocyanins; Anti-Inflammatory Agents; Catalysis; Cell Nucleus; Cytokines; Cytoprotection; Gene Expression Regulation; Glucosides; Glutathione Disulfide; Heme Oxygenase-1; HT29 Cells; Humans; Intestines; Intracellular Space; Mesalamine; NF-E2-Related Factor 2; PPAR gamma; Protein Subunits; Resveratrol; RNA, Messenger; Stilbenes | 2016 |
Determination of trans-resveratrol and its metabolites in rat serum using liquid chromatography with high-resolution time of flight mass spectrometry.
Topics: Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Chromatography, High Pressure Liquid; Deuterium Exchange Measurement; Female; Glucuronides; Limit of Detection; Rats; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes | 2016 |
Resveratrol inhibits lung cancer growth by suppressing M2-like polarization of tumor associated macrophages.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Culture Media, Conditioned; Cytokines; Humans; Lung Neoplasms; Macrophages; Mice; Resveratrol; STAT3 Transcription Factor; Stilbenes; Th2 Cells; Tumor Escape; Xenograft Model Antitumor Assays | 2017 |
Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Glycolysis; Hexokinase; Humans; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Engineering yeast for high-level production of stilbenoid antioxidants.
Topics: Antioxidants; Arabidopsis Proteins; Bioreactors; Biosynthetic Pathways; Cytochrome P-450 Enzyme System; Fermentation; Malonyl Coenzyme A; Metabolic Engineering; Phenylalanine; Promoter Regions, Genetic; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2016 |
Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart; HMGB1 Protein; Inflammation; Male; Membrane Glycoproteins; Mice; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Protective Agents; Resveratrol; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes | 2016 |
Development and characterization of resveratrol nanoemulsions carrying dual-imaging agents.
Topics: Biological Availability; Emulsions; Molecular Imaging; Resveratrol; Stilbenes; Tissue Distribution | 2016 |
Resveratrol and Coumarin: Novel Agricultural Antibacterial Agent against Ralstonia solanacearum In Vitro and In Vivo.
Topics: Anti-Bacterial Agents; Biofilms; Coumarins; Nicotiana; Plant Diseases; Ralstonia solanacearum; Resveratrol; Stilbenes | 2016 |
SIRT1-AMPK crosstalk is involved in high glucose-dependent impairment of insulin responsiveness in primary rat podocytes.
Topics: AMP-Activated Protein Kinases; Animals; Glucose; Insulin; Insulin Resistance; Phosphorylation; Podocytes; Rats; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes | 2016 |
Protection of resveratrol on acute kidney injury in septic rats.
Topics: Acute Kidney Injury; Animals; Cytokines; Glomerular Filtration Rate; Kidney; Male; Protective Agents; Rats, Sprague-Dawley; Renal Circulation; Resveratrol; Sepsis; Sirtuin 1; Stilbenes; Transcription Factor RelA | 2017 |
Enhanced colloidal stability, solubility and rapid dissolution of resveratrol by nanocomplexation with soy protein isolate.
Topics: Animals; Cell Line; Colloids; Delayed-Action Preparations; Drug Compounding; Drug Liberation; Drug Stability; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Hydrophobic and Hydrophilic Interactions; Macrophages; Mice; Nanoparticles; NF-kappa B; Particle Size; Resveratrol; Solubility; Soybean Proteins; Static Electricity; Stilbenes | 2017 |
Comparative proteomic analyses of the parietal lobe from rhesus monkeys fed a high-fat/sugar diet with and without resveratrol supplementation, relative to a healthy diet: Insights into the roles of unhealthy diets and resveratrol on function.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Brain; Diet, Healthy; Diet, High-Fat; Dietary Sugars; Dietary Supplements; Disease Models, Animal; Glutamate-Ammonia Ligase; Macaca mulatta; Male; Parietal Lobe; Proteome; Reproducibility of Results; Resveratrol; Signal Transduction; Stilbenes | 2017 |
The phytogestrogenic stilbenes, arachidin-1 and resveratrol, modulate regulatory T cell functions responsible for successful aging in aged ICR mice.
Topics: Age Factors; Aging; Animals; Biomarkers; Cytokines; Dietary Supplements; Female; Immunophenotyping; Lymphocyte Activation; Mice; Mice, Inbred ICR; Phenotype; Resveratrol; Stilbenes; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Tamoxifen | 2016 |
Resveratrol analogue, HS-1793, induces apoptotic cell death and cell cycle arrest through downregulation of AKT in human colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Chromones; Colonic Neoplasms; Cytochromes c; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; HCT116 Cells; Humans; Morpholines; Naphthols; Phosphorylation; Proto-Oncogene Proteins c-akt; Resorcinols; Resveratrol; Stilbenes | 2017 |
Resveratrol prevents endothelial progenitor cells from senescence and reduces the oxidative reaction via PPAR‑γ/HO‑1 pathways.
Topics: Adult; Animals; Antioxidants; Cells, Cultured; Cellular Senescence; Endothelial Progenitor Cells; Female; Gene Expression; Heme Oxygenase-1; Humans; Male; Nitric Oxide; Oxidative Stress; PPAR gamma; Rabbits; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Telomerase | 2016 |
Resveratrol solid lipid microparticles as dry powder formulation for nasal delivery, characterization and in vitro deposition study.
Topics: Administration, Intranasal; Anti-Inflammatory Agents; Cell Line; Chitosan; Drug Carriers; Humans; Lipids; Nasal Cavity; Particle Size; Powders; Resveratrol; Stilbenes | 2016 |
Efficiacy of resveratrol and quercetin after experimental spinal cord injury.
Topics: Animals; Antioxidants; Disease Models, Animal; Inflammation; Male; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Resveratrol; Spinal Cord Injuries; Stilbenes | 2016 |
Resveratrol and its methoxy derivatives modulate the expression of estrogen metabolism enzymes in breast epithelial cells by AhR down-regulation.
Topics: Basic Helix-Loop-Helix Transcription Factors; Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Down-Regulation; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Sulfotransferases | 2017 |
Front-face fluorescence spectroscopy combined with second-order multivariate algorithms for the quantification of polyphenols in red wine samples.
Topics: Algorithms; Chromatography, Liquid; Coumaric Acids; Polyphenols; Propionates; Resveratrol; Spectrometry, Fluorescence; Stilbenes; Wine | 2017 |
Resveratrol and cisplatin in a malignant mesothelioma cell model.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cisplatin; Drug Synergism; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Models, Biological; Resveratrol; Stilbenes | 2016 |
Resveratrol enhances the efficacy of sorafenib mediated apoptosis in human breast cancer MCF7 cells through ROS, cell cycle inhibition, caspase 3 and PARP cleavage.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 3; Cell Cycle Checkpoints; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Humans; MCF-7 Cells; Niacinamide; Phenylurea Compounds; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Resveratrol; Sorafenib; Stilbenes; Treatment Outcome | 2016 |
Resveratrol Inhibited Non-small Cell Lung Cancer Through Inhibiting STAT-3 Signaling.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Drug Screening Assays, Antitumor; Gene Transfer Techniques; Humans; Lung Neoplasms; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2016 |
Resveratrol prevents capacitation-like changes and improves in vitro fertilizing capability of buffalo frozen-thawed sperm.
Topics: Animals; Antioxidants; Buffaloes; Cell Survival; Cryopreservation; Dose-Response Relationship, Drug; Female; Insemination, Artificial; Male; Pregnancy; Resveratrol; Semen Preservation; Sperm Capacitation; Spermatozoa; Stilbenes | 2017 |
Resveratrol enhances brown adipocyte formation and function by activating AMP-activated protein kinase (AMPK) α1 in mice fed high-fat diet.
Topics: Adipocytes, Brown; Adipogenesis; Adipose Tissue, Brown; AMP-Activated Protein Kinases; Animals; Diet, High-Fat; Ion Channels; Mice; Mitochondrial Proteins; Obesity; Resveratrol; Stilbenes; Thermogenesis; Transcription Factors | 2017 |
A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet.
Topics: Adipocytes; Adipose Tissue, Brown; Adipose Tissue, White; Amino Acid Transport Systems, Neutral; Animals; Apoptosis Regulatory Proteins; Body Weight; Bone Morphogenetic Protein 4; Cyclooxygenase 2; Diet; Fatty Acid-Binding Proteins; Lipase; Quercetin; Rats; Resveratrol; RNA, Messenger; Stilbenes; Symporters; Uncoupling Protein 1 | 2017 |
Superparamagnetic nanoparticle-enhanced MRI of Alzheimer's disease plaques and activated microglia in 3X transgenic mouse brains: Contrast optimization.
Topics: Alleles; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidogenic Proteins; Animals; Brain; Contrast Media; Disease Models, Animal; Ferric Compounds; Homozygote; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Magnetite Nanoparticles; Metal Nanoparticles; Mice; Mice, Transgenic; Micelles; Microglia; Mutation; Plaque, Amyloid; Resveratrol; Stilbenes | 2017 |
SirT1 activator represses the transcription of TNF‑α in THP‑1 cells of a sepsis model via deacetylation of H4K16.
Topics: Acetylation; Cell Line; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation; Histones; Humans; Macrophages; Promoter Regions, Genetic; Protein Binding; Resveratrol; RNA, Messenger; Sepsis; Sirtuin 1; Stilbenes; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2016 |
Neurobehavioural evaluation of resveratrol in murine models of anxiety and schizophrenia.
Topics: Animals; Antioxidants; Antipsychotic Agents; Anxiety; Apomorphine; Behavior, Animal; Caloric Restriction; Exploratory Behavior; Female; Grooming; Male; Mice; Resveratrol; Schizophrenia; Schizophrenic Psychology; Stereotyped Behavior; Stilbenes; Swimming | 2017 |
The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4'-hydroxystilbene and trans-2,4',5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Hot Temperature; Longevity; Mutation; Oxidative Stress; Plant Extracts; Resveratrol; Stilbenes; Stress, Physiological; Transcription Factors | 2017 |
Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation.
Topics: Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Design; Enzyme Inhibitors; Histone Demethylases; Humans; Molecular Docking Simulation; Protein Conformation; Resveratrol; Stilbenes | 2017 |
Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring.
Topics: Adipocytes, Beige; Adipocytes, Brown; Animals; Diet, High-Fat; Energy Metabolism; Female; Male; Mice; Obesity; Pregnancy; Resveratrol; Stilbenes; Thermogenesis | 2017 |
Resveratrol attenuates MPP
Topics: Apoptosis; Caspase 3; Cell Line; Dopaminergic Neurons; Glycogen Synthase Kinase 3 beta; Humans; Mitochondria; Neuroprotective Agents; Oncogene Protein v-akt; Oxidative Stress; Piperidines; Pyrazoles; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Effects of resveratrol on P-glycoprotein and cytochrome P450 3A in vitro and on pharmacokinetics of oral saquinavir in rats.
Topics: Administration, Oral; Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Cell Line; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Dogs; Drug Interactions; Enzyme Inhibitors; Intestinal Absorption; Male; Microsomes; Rats; Rats, Sprague-Dawley; Resveratrol; Saquinavir; Stilbenes; Tandem Mass Spectrometry | 2016 |
Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation.
Topics: Binding Sites; Enzyme Activation; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Domains; Protein Stability; Resveratrol; Sirtuin 1; Stilbenes; Substrate Specificity; Tumor Suppressor Protein p53 | 2016 |
Effect of Resveratrol on periodontal pathogens during experimental periodontitis in rats.
Topics: Aggregatibacter actinomycetemcomitans; Animals; Anti-Bacterial Agents; Disease Models, Animal; Male; Periodontitis; Periodontium; Porphyromonas gingivalis; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Resveratrol; Stilbenes; Tannerella forsythia; Time Factors; Treatment Outcome | 2016 |
Improved Glucose Homeostasis in Obese Mice Treated With Resveratrol Is Associated With Alterations in the Gut Microbiome.
Topics: Animals; Bacteroides; Blood Glucose; Chromatography, Liquid; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Glucose; Glucose Tolerance Test; Homeostasis; Male; Mice; Mice, Obese; Obesity; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2017 |
Resveratrol and acetyl-resveratrol modulate activity of VEGF and IL-8 in ovarian cancer cell aggregates via attenuation of the NF-κB protein.
Topics: Cell Aggregation; Cell Line, Tumor; Cell Proliferation; Energy Metabolism; Female; Humans; Interleukin-8; NF-kappa B; Ovarian Neoplasms; Resveratrol; Signal Transduction; Spheroids, Cellular; Stilbenes; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A | 2016 |
Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase.
Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Dioxygenases; Electron Spin Resonance Spectroscopy; Models, Molecular; Recombinant Proteins; Resveratrol; Sphingomonadaceae; Stilbenes; Substrate Specificity | 2016 |
Selecting optimum protein nano-carriers for natural polyphenols using chemoinformatics tools.
Topics: Albumins; Antineoplastic Agents, Phytogenic; Carrier Proteins; Chemistry, Pharmaceutical; Curcumin; Drug Carriers; Gelatin; Humans; MCF-7 Cells; Molecular Docking Simulation; Nanoparticles; Polyphenols; Resveratrol; Stilbenes | 2016 |
A Molecular Electron Density Theory Study of the Chemical Reactivity of Cis- and Trans-Resveratrol.
Topics: Electrons; Models, Chemical; Resveratrol; Stereoisomerism; Stilbenes | 2016 |
Small molecules increase direct neural conversion of human fibroblasts.
Topics: Anilides; Benzazepines; Cell Line; Cellular Reprogramming; Cyclic AMP; Dinoprostone; Fetus; Fibroblasts; Gene Expression Regulation; Genetic Vectors; Glycogen Synthase Kinase 3 beta; Humans; Indoles; Lentivirus; Nerve Tissue Proteins; Neurons; Pyridines; Pyrimidines; Resveratrol; Small Molecule Libraries; Stilbenes; Transcription Factors; Transduction, Genetic | 2016 |
Resveratrol Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition by Increasing miR-200c Expression in HCT-116 Colorectal Cancer Cells.
Topics: Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; MicroRNAs; Neoplasm Invasiveness; Resveratrol; Stilbenes; Up-Regulation | 2017 |
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Topics: Animals; Antioxidants; Cells, Cultured; Glycerophosphates; Heme Oxygenase-1; Male; Mitochondria, Muscle; Muscle, Smooth, Vascular; NF-E2-Related Factor 2; Osteopontin; Oxidative Stress; Rats; Resveratrol; Sirtuin 1; Stilbenes; Vascular Calcification | 2016 |
In vitro detection of diesel exhaust particles induced human lung carcinoma epithelial cells damage and the effect of resveratrol.
Topics: A549 Cells; Antioxidants; Cell Cycle; Cytokines; Cytoskeleton; DNA Damage; Epithelial Cells; Humans; Membrane Potentials; Microscopy, Atomic Force; Particulate Matter; Resveratrol; Spectrum Analysis, Raman; Stilbenes; Surface Properties; Vehicle Emissions | 2017 |
Topics: Benzofurans; Chromatography, Liquid; Cyclopentanes; Flavanones; Flavonoids; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxylipins; Phenols; Plant Roots; Polycyclic Compounds; Resveratrol; Stilbenes; Vitis | 2016 |
The antileishmanial activity of xanthohumol is mediated by mitochondrial inhibition.
Topics: Animals; Antiprotozoal Agents; Cattle; Cell Line; Electron Transport; Electron Transport Complex III; Female; Flavonoids; Inhibitory Concentration 50; Leishmania; Macrophages, Peritoneal; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Propiophenones; Resveratrol; Stilbenes; Superoxides; Yeasts | 2017 |
The combined effect of resveratrol and diphenyleneiodonium on irradiation-induced injury to the hematopoietic system.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Drug Interactions; Drug Therapy, Combination; Hematopoietic System; Humans; Male; Mice; Mice, Inbred C57BL; Onium Compounds; Radiation Injuries, Experimental; Resveratrol; Stilbenes; Whole-Body Irradiation | 2017 |
Synthesis of resveratrol tetramers via a stereoconvergent radical equilibrium.
Topics: Benzofurans; Biological Products; Carbon; Dimerization; Indolequinones; Oxidation-Reduction; Resorcinols; Resveratrol; Stilbenes | 2016 |
Down-regulation of fibroblast growth factor 2 and its co-receptors heparan sulfate proteoglycans by resveratrol underlies the improvement of cardiac dysfunction in experimental diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Down-Regulation; Fibroblast Growth Factor 2; Gene Expression Regulation; Glypicans; Heart; Heparan Sulfate Proteoglycans; Rats, Wistar; Resveratrol; Stilbenes; Syndecan-4 | 2017 |
Resveratrol attenuates mitochondrial dysfunction in the liver of intrauterine growth retarded suckling piglets by improving mitochondrial biogenesis and redox status.
Topics: Animals; Animals, Newborn; DNA, Mitochondrial; Fetal Growth Retardation; Lipid Metabolism; Liver; Male; Mitochondria, Liver; Organelle Biogenesis; Oxidation-Reduction; Resveratrol; Stilbenes; Swine; Triglycerides; Weaning | 2017 |
Modulatory potential of resveratrol during lung inflammatory disease.
Topics: Acute Lung Injury; Antioxidants; Chromatin; DNA Damage; Flavonoids; Humans; Inflammation; Lung; Models, Theoretical; Neutrophils; Reactive Oxygen Species; Respiratory Function Tests; Resveratrol; Stilbenes | 2016 |
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; MicroRNAs; Mitochondria; Mitochondrial Dynamics; Neoplasms; Resveratrol; Stilbenes; Thyroid Hormone-Binding Proteins; Thyroid Hormones | 2016 |
Effect of resveratrol on resistin and apelin gene expressions in adipose tissue of diabetic rats.
Topics: Adipose Tissue; Animals; Apelin; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Rats; Rats, Wistar; Resistin; Resveratrol; Stilbenes | 2016 |
Enhanced Stilbene Production and Excretion in Vitis vinifera cv Pinot Noir Hairy Root Cultures.
Topics: Acetates; Benzofurans; beta-Cyclodextrins; Cyclopentanes; Glucosides; Oxylipins; Plant Roots; Resorcinols; Resveratrol; Stilbenes; Vitis | 2016 |
Antiadipogenic Effects and Mechanisms of Combinations of Genistein, Epigallocatechin-3-Gallate, and/or Resveratrol in Preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Catechin; CCAAT-Enhancer-Binding Protein-alpha; Fats; Genistein; Humans; Mice; PPAR gamma; Resveratrol; Stilbenes | 2017 |
Influence of glycosylation of deamidated wheat gliadin on its interaction mechanism with resveratrol.
Topics: Gliadin; Glycosylation; Humans; Hydrophobic and Hydrophilic Interactions; Resveratrol; Solubility; Stilbenes; Triticum | 2017 |
Skin targeting of resveratrol utilizing solid lipid nanoparticle-engrossed gel for chemically induced irritant contact dermatitis.
Topics: Animals; Dermatitis, Irritant; Dinitrochlorobenzene; Drug Carriers; Female; Gels; Humans; Irritants; Lipids; Male; Mice, Inbred BALB C; Nanoparticles; Rabbits; Resveratrol; Rheology; Skin; Stilbenes | 2017 |
Fabrication of chitosan-polycaprolactone composite nanofibrous scaffold for simultaneous delivery of ferulic acid and resveratrol.
Topics: Animals; Bandages; Chitosan; Coumaric Acids; Drug Delivery Systems; Nanofibers; Polyesters; Rats; Resveratrol; Stilbenes; Wound Healing | 2017 |
Physico-chemical characterization of succinyl chitosan-stabilized liposomes for the oral co-delivery of quercetin and resveratrol.
Topics: Chitosan; Drug Carriers; Liposomes; Particle Size; Quercetin; Resveratrol; Stilbenes | 2017 |
Protective features of resveratrol on human spermatozoa cryopreservation may be mediated through 5' AMP-activated protein kinase activation.
Topics: AMP-Activated Protein Kinases; Antioxidants; Cryopreservation; Humans; Male; Membrane Potential, Mitochondrial; Oxidative Stress; Phosphorylation; Protective Agents; Reactive Oxygen Species; Resveratrol; Semen Analysis; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes | 2017 |
Resveratrol alleviate hypoxic pulmonary hypertension via anti-inflammation and anti-oxidant pathways in rats.
Topics: Animals; Antioxidants; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; NF-E2-Related Factor 2; Random Allocation; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes; Thioredoxins | 2016 |
Gene expression profiles and physiological data from mice fed resveratrol-enriched rice DJ526.
Topics: Animals; Cellular Senescence; Diet; Mice; Oryza; Resveratrol; Stilbenes; Transcriptome | 2016 |
Metabolic Stress Induces Cognitive Disturbances and Inflammation in Aged Mice: Protective Role of Resveratrol.
Topics: 5-Methylcytosine; Animals; Biomarkers; Body Weight; Cognitive Dysfunction; Energy Intake; Gene Expression Regulation; Glucose Tolerance Test; Inflammation; Male; Maze Learning; Memory; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Phosphorylation; Oxidative Stress; Resveratrol; Stilbenes; Stress, Physiological | 2017 |
Nutritionally relevant concentrations of resveratrol and hydroxytyrosol mitigate oxidative burst of human granulocytes and monocytes and the production of pro-inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; CD11b Antigen; Dinoprostone; Granulocytes; Humans; Inflammation Mediators; Lipopolysaccharides; Mice; MicroRNAs; Monocytes; NF-E2-Related Factor 2; Nitric Oxide; Phenylethyl Alcohol; RAW 264.7 Cells; Respiratory Burst; Resveratrol; Stilbenes | 2017 |
HPLC Identification of Copper (II)-Trans-Resveratrol Complexes in Ethanolic Aqueous Solution.
Topics: Chromatography, High Pressure Liquid; Copper; Organometallic Compounds; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Wine | 2017 |
SIRT1‑mediated regulation of oxidative stress induced by Pseudomonas aeruginosa lipopolysaccharides in human alveolar epithelial cells.
Topics: A549 Cells; Alveolar Epithelial Cells; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lipopolysaccharides; Microscopy, Fluorescence; NF-kappa B; Niacinamide; Oxidative Stress; Pseudomonas aeruginosa; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Up-Regulation | 2017 |
Inhibitory effects of resveratrol on the adhesion, migration and invasion of human bladder cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Phosphorylation; Resveratrol; Stilbenes; Urinary Bladder; Urinary Bladder Neoplasms | 2017 |
miR-196b/miR-1290 participate in the antitumor effect of resveratrol via regulation of IGFBP3 expression in acute lymphoblastic leukemia.
Topics: 3' Untranslated Regions; Antineoplastic Agents, Phytogenic; Case-Control Studies; Cell Line, Tumor; Gene Expression Regulation, Leukemic; Humans; Insulin-Like Growth Factor Binding Protein 3; MicroRNAs; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; RNA, Small Interfering; Stilbenes | 2017 |
An integral study of cyclodextrins as solubility enhancers of α-methylstilbene, a resveratrol analogue.
Topics: Chromatography, High Pressure Liquid; Cyclodextrins; Entropy; Molecular Docking Simulation; Resveratrol; Solubility; Stilbenes; Thermodynamics | 2017 |
SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model.
Topics: Acetylation; Acute Kidney Injury; Animals; Apoptosis; Carbazoles; Cecum; Disease Models, Animal; Enzyme Activation; Epithelial Cells; Female; Histone Deacetylase Inhibitors; Kidney Tubules; Ligation; Male; Mitochondria; Oxidative Stress; Punctures; Rats, Sprague-Dawley; Resveratrol; Sepsis; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes; Superoxide Dismutase | 2016 |
Resveratrol upregulates SOCS1 production by lipopolysaccharide-stimulated RAW264.7 macrophages by inhibiting miR-155.
Topics: Animals; Cell Death; Cytokines; Down-Regulation; Interleukin-6; Janus Kinases; Lipopolysaccharides; Macrophages; Mice; MicroRNAs; p38 Mitogen-Activated Protein Kinases; RAW 264.7 Cells; Resveratrol; STAT Transcription Factors; Stilbenes; Suppressor of Cytokine Signaling 1 Protein; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Resveratrol Improves Cognitive Impairment by Regulating Apoptosis and Synaptic Plasticity in Streptozotocin-Induced Diabetic Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Glucose; Blotting, Western; Brain-Derived Neurotrophic Factor; Caspase 3; Cognition Disorders; Diabetes Mellitus, Experimental; Disease Models, Animal; Male; Maze Learning; Neuronal Plasticity; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Resveratrol; Stilbenes; Streptozocin; Up-Regulation | 2016 |
Resveratrol-loaded folic acid-grafted dextran stearate submicron particles exhibits enhanced antitumor efficacy in non-small cell lung cancers.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Dextrans; Drug Liberation; Folic Acid; Humans; Lung Neoplasms; Mitochondria; Particle Size; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Does Resveratrol Improve Insulin Signalling in HepG2 Cells?
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Forkhead Box Protein O1; Gene Expression Regulation; Hep G2 Cells; Humans; Insulin; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Resveratrol suppresses neuroinflammation in the experimental paradigm of autism spectrum disorders.
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; Inflammation; Male; Memory; Motor Activity; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
The Combination of Resveratrol and High-Fluence Light Emitting Diode-Red Light Produces Synergistic Photobotanical Inhibition of Fibroblast Proliferation and Collagen Synthesis: A Novel Treatment for Skin Fibrosis.
Topics: Antioxidants; Cell Line; Cell Proliferation; Collagen Type I; Collagen Type I, alpha 1 Chain; Color; Fibroblasts; Humans; Protein Biosynthesis; Resveratrol; Stilbenes | 2017 |
Resveratrol-induced antinociception is involved in calcium channels and calcium/caffeine-sensitive pools.
Topics: Analgesics; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Chelating Agents; Calcium Chloride; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Egtazic Acid; Male; Mice, Inbred ICR; Nociception; Nociceptive Pain; Phosphorylation; Reaction Time; Resveratrol; Ryanodine; Spinal Cord; Stilbenes; Time Factors | 2017 |
Protective effects of resveratrol against mancozeb induced apoptosis damage in mouse oocytes.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Cytoprotection; Epigenesis, Genetic; Female; Fertility; Fungicides, Industrial; Gene Expression Regulation, Developmental; Maneb; Mice, Inbred ICR; Oocytes; Ovarian Follicle; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Zineb | 2017 |
SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Medulloblastoma; Molecular Chaperones; Protein Inhibitors of Activated STAT; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Suppressor of Cytokine Signaling 3 Protein | 2016 |
Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression.
Topics: Acetylation; Animals; Benzamides; Cell Differentiation; Chagas Disease; Chlorocebus aethiops; DNA Replication; Gene Expression; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Naphthols; Resveratrol; Stilbenes; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2017 |
Assessment of the effect of adding L-carnitine and/or resveratrol to maturation medium before vitrification on in vitro-matured calf oocytes.
Topics: Animals; Blastocyst; Carnitine; Cattle; Cryopreservation; Embryonic Development; Female; Gene Expression Regulation, Developmental; In Vitro Oocyte Maturation Techniques; Oocytes; Resveratrol; Stilbenes; Vitrification | 2017 |
Resveratrol Ameliorates Palmitate-Induced Inflammation in Skeletal Muscle Cells by Attenuating Oxidative Stress and JNK/NF-κB Pathway in a SIRT1-Independent Mechanism.
Topics: Animals; Cell Line; Inflammation; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Muscle Fibers, Skeletal; Muscle Proteins; NF-kappa B; Oxidative Stress; Palmitic Acid; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Resveratrol Intervenes Cholesterol- and Isoprenoid-Mediated Amyloidogenic Processing of AβPP in Familial Alzheimer's Disease.
Topics: ADAM10 Protein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Antioxidants; Aspartic Acid Endopeptidases; CHO Cells; Cholesterol; Cricetulus; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Membrane Proteins; Mutation; Peptide Hydrolases; Resveratrol; Sirtuin 1; Stilbenes; Terpenes; Transfection | 2017 |
Synthesis and biological evaluation of deferiprone-resveratrol hybrids as antioxidants, Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Chelating Agents; Chemistry Techniques, Synthetic; Copper; Deferiprone; Drug Design; Iron; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Protein Structure, Secondary; Pyridones; Resveratrol; Stilbenes; Structure-Activity Relationship | 2017 |
Role of nutraceutical SIRT1 modulators in AMPK and mTOR pathway: Evidence of a synergistic effect.
Topics: AMP-Activated Protein Kinases; Anthocyanins; Berberine; Catechin; Cell Line, Tumor; Cell Survival; Coumaric Acids; Curcumin; Dietary Supplements; Gene Expression Regulation; Humans; Niclosamide; Phenylethyl Alcohol; Phosphorylation; Quercetin; Resveratrol; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Functional response of novel bioprotective poloxamer-structured vesicles on inflamed skin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Edema; Female; Fibroblasts; Gallic Acid; Liposomes; Mice; Oxidative Stress; Poloxamer; Resveratrol; Skin; Skin Absorption; Stilbenes; Swine | 2017 |
Pectin-zinc-chitosan-polyethylene glycol colloidal nano-suspension as a food grade carrier for colon targeted delivery of resveratrol.
Topics: Chitosan; Colloids; Colon; Drug Carriers; Drug Liberation; Food; Nanoparticles; Particle Size; Pectins; Polyethylene Glycols; Resveratrol; Stilbenes; Suspensions; Zinc | 2017 |
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Humans; Ligands; Liver; Molecular Targeted Therapy; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Resveratrol; Stilbenes; Tacrine | 2017 |
Resveratrol-Mediated Expression of KLF15 in the Ischemic Myocardium is Associated with an Improved Cardiac Phenotype.
Topics: Animals; Antioxidant Response Elements; Antioxidants; Disease Models, Animal; Kruppel-Like Transcription Factors; Male; Myocardial Infarction; Myocardium; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Phenotype; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Time Factors; Up-Regulation; Ventricular Remodeling | 2017 |
Bioavailability-enhanced Resveramax™ modulates quorum sensing and inhibits biofilm formation in Pseudomonas aeruginosa PAO1.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Biological Availability; Biosensing Techniques; Drug Synergism; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Protein Binding; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Resveratrol; Stilbenes; Trans-Activators | 2017 |
Anti-inflammatory effect of resveratrol in human coronary arterial endothelial cells via induction of autophagy: implication for the treatment of Kawasaki disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Cells, Cultured; Coronary Vessels; Endothelial Cells; Humans; Inflammation Mediators; Mucocutaneous Lymph Node Syndrome; Nitric Oxide Synthase Type II; Resveratrol; Stilbenes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Inhaled resveratrol treatments slow ageing-related degenerative changes in mouse lung.
Topics: Administration, Inhalation; Aging; Animals; Antioxidants; Blotting, Western; DNA Damage; In Situ Nick-End Labeling; Lung; Mice; Mice, Inbred C57BL; Respiratory Function Tests; Resveratrol; Stilbenes | 2017 |
Influence of resveratrol on endoplasmic reticulum stress and expression of adipokines in adipose tissues/adipocytes induced by high-calorie diet or palmitic acid.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Adipose Tissue; Animals; Cell Differentiation; Endoplasmic Reticulum Stress; Insulin Resistance; Lipids; Male; Mice; Palmitic Acid; Resveratrol; Stilbenes | 2017 |
Resveratrol modulates GSH system in C6 astroglial cells through heme oxygenase 1 pathway.
Topics: Animals; Astrocytes; Buthionine Sulfoximine; Cell Line; Cell Survival; Cytokines; Glutathione; Heme Oxygenase-1; Male; Oxidative Stress; Rats; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Sinonasal Delivery of Resveratrol via Mucoadhesive Nanostructured Microparticles in a Nasal Polyp Mouse Model.
Topics: Adhesives; Administration, Intranasal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Male; Mice, Inbred BALB C; Nanoparticles; Nasal Mucosa; Nasal Polyps; Resveratrol; Rhinitis; Sinusitis; Stilbenes | 2017 |
Resveratrol suppresses human hepatocellular carcinoma via targeting HGF-c-Met signaling pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Gene Knockdown Techniques; Hepatocyte Growth Factor; Humans; Liver Neoplasms; Mice, Nude; Molecular Targeted Therapy; Phosphorylation; Proto-Oncogene Proteins c-met; Resveratrol; Signal Transduction; Stilbenes; Xenograft Model Antitumor Assays | 2017 |
Sensitization of Radioresistant Prostate Cancer Cells by Resveratrol Isolated from Arachis hypogaea Stems.
Topics: Animals; Apoptosis; Arachis; Cell Line, Tumor; Chemoradiotherapy; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Plant Stems; Prostatic Neoplasms; Radiation Tolerance; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays | 2017 |
Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway.
Topics: beta Catenin; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Epithelial-Mesenchymal Transition; Glioma; Humans; Neoplastic Stem Cells; Proto-Oncogene Proteins c-myc; Resveratrol; Stilbenes; Wnt Signaling Pathway | 2017 |
Melatonin and resveratrol reverse the toxic effect of high boron (B) and modulate biochemical parameters in pepper plants (Capsicum annuum L.).
Topics: Antioxidants; Biomass; Boron; Capsicum; Carbohydrates; Carotenoids; Chlorophyll; Electrolytes; Fruit; Melatonin; Phenols; Photosynthesis; Plant Development; Plant Leaves; Plant Roots; Plant Stems; Resveratrol; Stilbenes; Water | 2017 |
Resveratrol limits epithelial to mesenchymal transition through modulation of KHSRP/hnRNPA1-dependent alternative splicing in mammary gland cells.
Topics: Alternative Splicing; Animals; Cytoskeletal Proteins; Epithelial-Mesenchymal Transition; Female; Heterogeneous Nuclear Ribonucleoprotein A1; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Hyaluronan Receptors; Mammary Glands, Animal; Mice; Microfilament Proteins; Receptor, Fibroblast Growth Factor, Type 2; Resveratrol; RNA-Binding Proteins; Stilbenes | 2017 |
Resveratrol and capsaicin used together as food complements reduce tumor growth and rescue full efficiency of low dose gemcitabine in a pancreatic cancer model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Capsaicin; Cell Cycle; Cell Line, Tumor; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Effect of resveratrol and tetracycline on the subacute paraquat toxicity in mice.
Topics: Animals; Antioxidants; Brain; Catalase; Cytokines; Electron Transport Complex I; Glutathione; Glutathione Peroxidase; Herbicides; Lung; Male; Malondialdehyde; Mice; Mitochondrial Membranes; Oxidative Stress; Paraquat; Protein Synthesis Inhibitors; Resveratrol; Stilbenes; Tetracycline; Toxicity Tests, Subacute | 2017 |
Low dose resveratrol ameliorates mitochondrial respiratory dysfunction and enhances cellular reprogramming.
Topics: Antioxidants; Cell Respiration; Cells, Cultured; Cellular Reprogramming; Fibroblasts; Humans; Mitochondria; Pluripotent Stem Cells; Resveratrol; Stilbenes | 2017 |
Topics: Anti-Bacterial Agents; Biofilms; Citric Acid Cycle; Gene Expression Regulation, Bacterial; Glycolysis; Metabolic Networks and Pathways; Metabolomics; Nuclear Magnetic Resonance, Biomolecular; Oxidative Stress; Plant Extracts; Protein Biosynthesis; Pseudomonas aeruginosa; Pyocyanine; Quorum Sensing; Resveratrol; Smilax; Stilbenes; Virulence Factors | 2017 |
Effect of resveratrol on platelet aggregation by fibrinogen protection.
Topics: Epinephrine; Fibrinogen; Humans; Microscopy, Electrochemical, Scanning; Platelet Aggregation; Protective Agents; Protein Conformation; Resveratrol; Spectrum Analysis; Stilbenes | 2017 |
Development of a Topical Resveratrol Formulation for Commercial Applications Using Dendrimer Nanotechnology.
Topics: Animals; Antioxidants; Dendrimers; Diffusion Chambers, Culture; Drug Stability; Humans; Hydrogen-Ion Concentration; Permeability; Polysorbates; Rats; Resveratrol; Skin; Skin Cream; Solubility; Stilbenes; Water | 2017 |
Effect and mechanism of resveratrol on drug resistance in human bladder cancer cells.
Topics: Antineoplastic Agents; Biomarkers; Cell Cycle; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drugs, Chinese Herbal; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Resveratrol; RNA, Messenger; Stilbenes; Urinary Bladder Neoplasms | 2017 |
Surfactant-Free Preparation of Au@Resveratrol Hollow Nanoparticles with Photothermal Performance and Antioxidant Activity.
Topics: Antioxidants; Gold; Metal Nanoparticles; Resveratrol; Stilbenes; Surface-Active Agents | 2017 |
Effect of Combinatory Treatment With Resveratrol and Guggulsterone on Mild Acute Pancreatitis in Mice.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ceruletide; Chemokines; Cytokines; Female; Mice, Inbred C57BL; NF-kappa B; Pancreatitis; Pregnenediones; Resveratrol; STAT3 Transcription Factor; Stilbenes | 2017 |
[Streptococcus pneumoniae induces SPLUNC1 and the regulatory effects of resveratrol].
Topics: Bronchi; Cells, Cultured; Cytoprotection; Epithelial Cells; Glycoproteins; Humans; Phosphoproteins; Resveratrol; RNA, Messenger; Stilbenes; Streptococcus pneumoniae | 2017 |
Resveratrol inhibits adventitial fibroblast proliferation and induces cell apoptosis through the SIRT1 pathway.
Topics: Animals; Apoptosis; Cell Movement; Cells, Cultured; Fibroblasts; Male; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes; Up-Regulation | 2017 |
Resveratrol Co-Treatment Attenuates the Effects of HIV Protease Inhibitors on Rat Body Weight and Enhances Cardiac Mitochondrial Respiration.
Topics: Animals; Body Weight; HIV Protease Inhibitors; Male; Mitochondria, Heart; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Sirtuin 1 independent effects of resveratrol in INS-1E β-cells.
Topics: Animals; Cell Line; Cell Size; Enzyme Inhibitors; Gene Knockdown Techniques; Insulin-Secreting Cells; Rats; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Postnatal resveratrol supplementation improves cardiovascular function in male and female intrauterine growth restricted offspring.
Topics: AMP-Activated Protein Kinases; Animals; Body Weight; Cardiovascular Diseases; Eating; Female; Fetal Growth Retardation; Heart; Male; Myocardium; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2017 |
Improving key enzyme activity in phenylpropanoid pathway with a designed biosensor.
Topics: Biosensing Techniques; Biosynthetic Pathways; Coenzyme A Ligases; Coumaric Acids; Enzyme Activation; Escherichia coli; Flavanones; Gene Expression Regulation, Enzymologic; Genetic Enhancement; Metabolic Engineering; Metabolic Networks and Pathways; Propanols; Resveratrol; Stilbenes; Up-Regulation | 2017 |
Growth-Inhibiting Activity of Resveratrol Imine Analogs on Tumor Cells In Vitro.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Humans; Imines; Resveratrol; Stilbenes | 2017 |
Rehabilitation Training and Resveratrol Improve the Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through the Sirt1 Signaling Pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Combined Modality Therapy; Exercise Therapy; Male; Movement Disorders; Neurological Rehabilitation; Rats; Rats, Sprague-Dawley; Recovery of Function; Resveratrol; Sirtuin 1; Stilbenes; Treatment Outcome | 2016 |
Optimized Extraction of Resveratrol from
Topics: Antioxidants; Arachis; Microwaves; Phenols; Resveratrol; Stilbenes | 2016 |
The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development.
Topics: AMP-Activated Protein Kinases; Analgesics; Anesthetics, Local; Animals; Binding Sites; Biphenyl Compounds; Drug Evaluation, Preclinical; HEK293 Cells; Hot Temperature; Humans; Male; meta-Aminobenzoates; Metformin; NAV1.7 Voltage-Gated Sodium Channel; Neural Conduction; Pain; Patch-Clamp Techniques; Pyrones; Rats; Rats, Sprague-Dawley; Reaction Time; Recombinant Fusion Proteins; Resveratrol; Sensory Receptor Cells; Sodium Channel Blockers; Stilbenes; Thiazoles; Thiophenes; Trigeminal Ganglion | 2017 |
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Cell Survival; Doxorubicin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Mice; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; Stomach Neoplasms; Xenograft Model Antitumor Assays | 2017 |
Niosome-based hydrogel of resveratrol for topical applications: An effective therapy for pain related disorder(s).
Topics: Administration, Topical; Animals; Dialysis; Edema; Hydrogel, Polyethylene Glycol Dimethacrylate; Kinetics; Liposomes; Male; Pain; Particle Size; Rats, Wistar; Resveratrol; Rheology; Skin Absorption; Stilbenes; Surface-Active Agents; Suspensions | 2017 |
Protective effect of resveratrol against inflammation, oxidative stress and apoptosis in pancreas of aged SAMP8 mice.
Topics: Aging; Animals; Antioxidants; Apoptosis; Inflammation; Male; Mice; NF-kappa B; Oxidative Stress; Pancreas; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes | 2017 |
Carbon monoxide ameliorates hepatic ischemia/reperfusion injury via sirtuin 1-mediated deacetylation of high-mobility group box 1 in rats.
Topics: Acetylation; Animals; Carbazoles; Carbon Monoxide; HMGB1 Protein; Inflammation; Liver; Liver Transplantation; Male; Mice; Organometallic Compounds; Protective Agents; Rats; Rats, Sprague-Dawley; RAW 264.7 Cells; Reperfusion Injury; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Long-term low dose dietary resveratrol supplement reduces cardiovascular structural and functional deterioration in chronic heart failure in rats.
Topics: Animals; Cardiotonic Agents; Chronic Disease; Collagen; Dietary Supplements; Disease Models, Animal; Drug Administration Schedule; Echocardiography; Fibrosis; Heart Failure; Male; Myocardial Contraction; Myocardium; Pulse Wave Analysis; Rats, Wistar; Resveratrol; Stilbenes; Stroke Volume; Time Factors; Vascular Stiffness; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Chemical Composition Analysis, Sensory, and Feasibility Study of Tree Peony Seed.
Topics: alpha-Linolenic Acid; Antioxidants; Chromans; Feasibility Studies; Food Analysis; gamma-Tocopherol; Glucosides; Linseed Oil; Monoterpenes; Nutritive Value; Oxidation-Reduction; Paeonia; Phenols; Resveratrol; Seeds; Species Specificity; Stilbenes; Trees; Vitamin E | 2017 |
Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Humans; Resveratrol; Retinal Pigment Epithelium; Signal Transduction; Smad2 Protein; Smad3 Protein; Stilbenes; Structure-Activity Relationship; Transforming Growth Factor beta2 | 2017 |
Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction.
Topics: Animals; Antigens, Ly; Apoptosis; Biomarkers; Chemokine CXCL12; Disease Models, Animal; Male; Membrane Proteins; Mice; Myoblasts, Cardiac; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Regeneration; Resveratrol; Stem Cells; Stilbenes; Vascular Endothelial Growth Factor A | 2017 |
Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling.
Topics: Adult; Aging; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Caloric Restriction; Cells, Cultured; Cellular Senescence; Epithelial-Mesenchymal Transition; Glucose; Humans; Hypoglycemic Agents; Kidney Tubules, Proximal; Male; Metformin; Microscopy, Fluorescence; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Systemic administration of the dietary constituent resveratrol inhibits the nociceptive jaw-opening reflex in rats via the endogenous opioid system.
Topics: Administration, Intravenous; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Electromyography; Jaw; Male; Naloxone; Nociception; Opioid Peptides; Rats; Reflex; Resveratrol; Stilbenes | 2017 |
Disparate Effects of Stilbenoid Polyphenols on Hypertrophic Cardiomyocytes In Vitro vs. in the Spontaneously Hypertensive Heart Failure Rat.
Topics: Animals; Blood Pressure; Cardiomegaly; Cell Survival; Disease Models, Animal; Heart Failure; Heart Function Tests; MAP Kinase Signaling System; Myocytes, Cardiac; Polyphenols; Rats; Rats, Inbred SHR; Resveratrol; Stilbenes | 2017 |
Resveratrol induces mitochondria-mediated, caspase-independent apoptosis in murine prostate cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase Inhibitors; Caspases; Cell Cycle Proteins; Cell Proliferation; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Prostatic Neoplasms; Resveratrol; Stilbenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
Comparison of methods for analysis of resveratrol in dietary vegetable supplements.
Topics: Chromatography, High Pressure Liquid; Dietary Supplements; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Vegetables | 2017 |
Resveratrol improves exercise performance and skeletal muscle oxidative capacity in heart failure.
Topics: Animals; Antioxidants; Energy Metabolism; Exercise Tolerance; Fatigue; Glucose; Heart Failure; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Microbiota; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Physical Conditioning, Animal; Physical Exertion; Resveratrol; Stilbenes; Stroke Volume | 2017 |
Distribution of trans-resveratrol and its metabolites after acute or sustained administration in mouse heart, brain, and liver.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Glucuronides; Heart; Liver; Mass Spectrometry; Mice; Resveratrol; Stilbenes; Tissue Distribution | 2017 |
Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy.
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; Disease Models, Animal; Down-Regulation; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; GluK2 Kainate Receptor; Glutamic Acid; Kainic Acid; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Kainic Acid; Resveratrol; Stilbenes; Up-Regulation | 2017 |
Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol.
Topics: Animals; Antioxidants; Cell Differentiation; Cell Proliferation; Cells, Cultured; Coronary Restenosis; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Smad3 Protein; Stilbenes; Transforming Growth Factor beta | 2017 |
Enhanced antitumor efficacy of resveratrol-loaded nanocapsules in colon cancer cells: physicochemical and biological characterization.
Topics: Antineoplastic Agents; Apoptosis; Colonic Neoplasms; Drug Carriers; HT29 Cells; Humans; Lipids; Nanocapsules; Resveratrol; Stilbenes | 2017 |
Resveratrol prevents ammonia-induced mitochondrial dysfunction and cellular redox imbalance in C6 astroglial cells.
Topics: Ammonia; Animals; Antioxidants; Astrocytes; Catalase; Cell Line; Creatine Kinase; DNA Damage; Glutathione; Glutathione Peroxidase; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
Resveratrol and Epigallocatechin-3-gallate addition to thawed boar sperm improves in vitro fertilization.
Topics: Acrosome; Animals; Antioxidants; Catechin; Cryopreservation; Dose-Response Relationship, Drug; Female; Fertilization in Vitro; Male; Resveratrol; Semen Preservation; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Stilbenes; Sus scrofa | 2017 |
Resveratrol ameliorates oxidative stress and organ dysfunction in Schistosoma mansoni infected mice.
Topics: Animals; Antioxidants; Blood Proteins; Brain; Catalase; Cholesterol; Glutathione; Kidney; Liver; Lung; Male; Mice; Oxidative Stress; Receptor for Advanced Glycation End Products; Resveratrol; Schistosoma mansoni; Schistosomiasis mansoni; Specific Pathogen-Free Organisms; Spleen; Stilbenes; Superoxide Dismutase; tau Proteins; Triglycerides | 2017 |
Characterization of Stilbene Synthase Genes in Mulberry (Morus atropurpurea) and Metabolic Engineering for the Production of Resveratrol in Escherichia coli.
Topics: Acyltransferases; Biosynthetic Pathways; Escherichia coli; Metabolic Engineering; Morus; Nicotiana; Plant Proteins; Resveratrol; Stilbenes | 2017 |
Apigenin alleviates STZ-induced diabetic cardiomyopathy.
Topics: Animals; Antioxidants; Apigenin; Cardiotonic Agents; Cell Line; Diabetic Cardiomyopathies; Gene Expression Regulation; Humans; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Rats; Resveratrol; Stilbenes; Streptozocin | 2017 |
Vitamin D Combined with Resveratrol Prevents Cognitive Decline in SAMP8 Mice.
Topics: Aging; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antioxidants; Aspartic Acid Endopeptidases; Brain; Cathepsin B; Cognition; Cognition Disorders; Disease Models, Animal; Drug Therapy, Combination; Glycogen Synthase Kinase 3; In Situ Nick-End Labeling; Mice; Nerve Tissue Proteins; Peptide Fragments; Resveratrol; Signal Transduction; Stilbenes; tau Proteins; Vitamin D | 2017 |
Differential sensitivities of bladder cancer cell lines to resveratol are unrelated to its metabolic profile.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arylsulfotransferase; Cell Line, Tumor; Cell Proliferation; Humans; Rats; Resveratrol; Stilbenes; Urinary Bladder Neoplasms | 2017 |
Manganese neurotoxicity and protective effects of resveratrol and quercetin in preclinical research.
Topics: alpha-Tocopherol; Animals; Caspase 3; Catalase; Glutathione; Male; Malondialdehyde; Manganese; Neurotoxicity Syndromes; Oxidation-Reduction; Oxidative Stress; Protective Agents; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Vitamin E | 2017 |
Resveratrol enhances the radiosensitivity of nasopharyngeal carcinoma cells by downregulating E2F1.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Chemoradiotherapy; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nasopharyngeal Neoplasms; Proto-Oncogene Proteins c-akt; Radiation Tolerance; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
Protective impact of resveratrol in experimental rat model of hyperoxaluria.
Topics: Animals; Antioxidants; Biopsy, Needle; Disease Models, Animal; Ethylene Glycol; Hyperoxaluria; Immunohistochemistry; Kidney Calculi; Male; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Reference Values; Resveratrol; Statistics, Nonparametric; Stilbenes | 2017 |
A New Anti-Aging Lysophosphatidic Acid from Arabidopsis thaliana.
Topics: Aging; Arabidopsis; DNA-Binding Proteins; Heat-Shock Proteins; Hydrogen Peroxide; Lysophospholipids; Membrane Proteins; Mitochondrial Proteins; Mutation; Oxidative Stress; Resveratrol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Stilbenes; Superoxide Dismutase; Superoxide Dismutase-1; Transcription Factors | 2017 |
Bifunctional viscous nanovesicles co-loaded with resveratrol and gallic acid for skin protection against microbial and oxidative injuries.
Topics: Animals; Animals, Newborn; Anti-Infective Agents, Local; Antioxidants; Cell Survival; Drug Stability; Fibroblasts; Gallic Acid; Humans; In Vitro Techniques; Keratinocytes; Liposomes; Particle Size; Phospholipids; Resveratrol; Skin Diseases; Skin Diseases, Bacterial; Stilbenes; Swine; Viscosity | 2017 |
Effective inhibition of MERS-CoV infection by resveratrol.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Coronavirus Infections; Middle East Respiratory Syndrome Coronavirus; Protein Binding; Resveratrol; RNA-Binding Proteins; RNA, Viral; Stilbenes; Vero Cells; Viral Proteins | 2017 |
Preparation and in-vitro/in-vivo characterization of trans-resveratrol nanocrystals for oral administration.
Topics: Administration, Oral; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Liberation; Drug Stability; Humans; Lecithins; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Poloxamer; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vitamin E | 2017 |
Different effect of resveratrol to induction of apoptosis depending on the type of human cancer cells.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Fragmentation; Enzyme Activation; HCT116 Cells; Hep G2 Cells; Humans; MCF-7 Cells; Mitochondria; Neoplasms; Proto-Oncogene Proteins c-akt; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Resveratrol-induced autophagy and apoptosis in cisplatin-resistant human oral cancer CAR cells: A key role of AMPK and Akt/mTOR signaling.
Topics: Amino Acid Chloromethyl Ketones; AMP-Activated Protein Kinases; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Autophagy-Related Protein 12; Autophagy-Related Protein 5; Beclin-1; Caspase 3; Caspase 9; Cell Line, Tumor; Cisplatin; DNA Fragmentation; Drug Resistance, Neoplasm; Humans; Microtubule-Associated Proteins; Mouth Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Development of Water-Triggered Chitosan Film Containing Glucamylase for Sustained Release of Resveratrol.
Topics: Amylases; beta-Cyclodextrins; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Glucose; Hydrogen-Ion Concentration; Hydrolysis; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2017 |
De novo biosynthesis of pterostilbene in an Escherichia coli strain using a new resveratrol O-methyltransferase from Arabidopsis.
Topics: Acyltransferases; Ammonia-Lyases; Arabidopsis; Biocatalysis; Escherichia coli; Metabolic Engineering; Metabolic Networks and Pathways; Methionine; Methyltransferases; Resveratrol; S-Adenosylmethionine; Stilbenes; Tyrosine | 2017 |
Lycopene, resveratrol, vitamin C and FeSO
Topics: 4-Nitroquinoline-1-oxide; Animals; Antioxidants; Ascorbic Acid; Carcinogens; Carotenoids; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Female; Ferrous Compounds; Larva; Lycopene; Male; Resveratrol; Stilbenes; Toxicity Tests; Wings, Animal; Xenobiotics | 2017 |
Structural features of Zika virus non-structural proteins 3 and -5 and its individual domains in solution as well as insights into NS3 inhibition.
Topics: Antioxidants; Enzyme Inhibitors; Models, Molecular; Peptide Hydrolases; Protein Conformation; Protein Domains; Quercetin; Resveratrol; RNA Helicases; Scattering, Small Angle; Serine Endopeptidases; Solutions; Stilbenes; Viral Nonstructural Proteins; X-Ray Diffraction; Zika Virus | 2017 |
Resveratrol inhibits the IL-1β-induced expression of MMP-13 and IL-6 in human articular chondrocytes via TLR4/MyD88-dependent and -independent signaling cascades.
Topics: Aged; Biomarkers; Cell Survival; Chondrocytes; Gene Expression; Humans; Interleukin-1beta; Interleukin-6; Matrix Metalloproteinase 13; Middle Aged; Myeloid Differentiation Factor 88; Osteoarthritis; Phenotype; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4 | 2017 |
Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Drug Compounding; Drug Delivery Systems; Drug Liberation; Grape Seed Extract; Immunoconjugates; Lipids; Nanoparticles; Particle Size; Permeability; Plant Extracts; Protein Aggregates; Protein Aggregation, Pathological; Resveratrol; Stilbenes; Vitis | 2017 |
Resveratrol decreases FoXO protein expression through PI3K-Akt-dependent pathway inhibition in H₂O₂-treated synoviocytes.
Topics: Antioxidants; Apoptosis; Arthritis, Rheumatoid; Cells, Cultured; Forkhead Transcription Factors; Humans; Hydrogen Peroxide; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Synoviocytes | 2017 |
Resveratrol induces cell cycle arrest and apoptosis with docetaxel in prostate cancer cells via a p53/ p21WAF1/CIP1 and p27KIP1 pathway.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Docetaxel; Drug Synergism; Humans; Immunoblotting; Male; Microscopy, Fluorescence; Prostatic Neoplasms; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes; Taxoids; Tumor Suppressor Protein p53 | 2017 |
A new strategy to enhance the biosynthesis of trans-resveratrol by overexpressing stilbene synthase gene in elicited Vitis vinifera cell cultures.
Topics: Acetates; Acyltransferases; Agrobacterium; Cell Line; Cell Survival; Cells, Cultured; Cyclodextrins; Cyclopentanes; Gene Expression Regulation, Plant; Oxylipins; Plant Growth Regulators; Plants, Genetically Modified; Resveratrol; Stilbenes; Transformation, Genetic; Vitis | 2017 |
SIRT1 Regulates the Inflammatory Response of Vascular Adventitial Fibroblasts through Autophagy and Related Signaling Pathway.
Topics: Adventitia; Animals; Autophagy; Benzamides; Cells, Cultured; Fibroblasts; Heterocyclic Compounds, 3-Ring; Interleukin-1beta; Interleukin-6; Male; Naphthols; NLR Family, Pyrin Domain-Containing 3 Protein; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirolimus; Sirtuin 1; Stilbenes; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol regulates neuronal glucose uptake and insulin sensitivity via P21-activated kinase 2 (PAK2).
Topics: 4-Chloro-7-nitrobenzofurazan; AMP-Activated Protein Kinases; Animals; Antioxidants; Blotting, Western; Cell Line; Cell Line, Tumor; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Insulin; Neurons; p21-Activated Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2017 |
Increased intestinal permeation and modulation of presystemic metabolism of resveratrol formulated into self-emulsifying drug delivery systems.
Topics: Animals; Drug Compounding; Drug Delivery Systems; Emulsifying Agents; Intestinal Absorption; Intestinal Mucosa; Male; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2017 |
Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection.
Topics: Antiviral Agents; Cell Line, Tumor; Cell Nucleus; Dengue; Dengue Virus; HMGB1 Protein; Humans; Interferon Type I; Interferon-beta; Myxovirus Resistance Proteins; Promoter Regions, Genetic; Protein Binding; Resveratrol; RNA Interference; RNA, Small Interfering; Sirtuin 1; Stilbenes; Virus Replication | 2017 |
Comparative effects of energy restriction and resveratrol intake on glycemic control improvement.
Topics: Adiponectin; Animals; Antioxidants; Blood Glucose; Caloric Restriction; Diet, High-Fat; Fructosamine; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Leptin; Male; Muscle, Skeletal; Obesity; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Insulin; Resveratrol; Stilbenes; Sucrose; Triglycerides | 2017 |
The protective effects of resveratrol, H
Topics: Animals; Apoptosis; Cadmium Compounds; Cell Line; Cell Survival; Hydrogen Sulfide; Hyperthermia, Induced; MAP Kinase Kinase 4; Mice; p38 Mitogen-Activated Protein Kinases; Protective Agents; Proto-Oncogene Proteins c-akt; Quantum Dots; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Tellurium | 2017 |
Transport-Glucuronidation Classification System and PBPK Modeling: New Approach To Predict the Impact of Transporters on Disposition of Glucuronides.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Glucuronides; Glucuronosyltransferase; HeLa Cells; Humans; Kinetics; Liver; Male; Mice; Mice, Knockout; Resveratrol; Stilbenes | 2017 |
A Combination of Resveratrol and Curcumin is Effective Against Aluminum Chloride-Induced Neuroinflammation in Rats.
Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Brain; Catalase; Chlorides; Curcumin; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Encephalitis; Glutathione Transferase; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
A simple LC-MS/MS method for the simultaneous quantification of resveratrol and its major phase II metabolites: Assessment of their urinary and biliary excretions in rats.
Topics: Animals; Antioxidants; Chromatography, High Pressure Liquid; Hepatobiliary Elimination; Limit of Detection; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2017 |
Resveratrol Enhances Self-Renewal of Mouse Embryonic Stem Cells.
Topics: Animals; Cell Differentiation; Cell Line; Cell Proliferation; Embryonic Stem Cells; Mice; Pluripotent Stem Cells; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Green Hydroselenation of Aryl Alkynes: Divinyl Selenides as a Precursor of Resveratrol.
Topics: Alkynes; Catalysis; Chemistry Techniques, Synthetic; Organoselenium Compounds; Resveratrol; Selenium; Stilbenes; Tellurium | 2017 |
Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Humans; Neoplasm Invasiveness; Phosphoproteins; Resveratrol; rhoA GTP-Binding Protein; Signal Transduction; Stilbenes; Transcription Factors; YAP-Signaling Proteins | 2017 |
Resveratrol stimulates mitochondrial fusion by a mechanism requiring mitofusin-2.
Topics: Animals; Antioxidants; Cell Line; Cell Line, Tumor; Cell Proliferation; Gene Deletion; GTP Phosphohydrolases; Humans; Mice; Mitochondria; Mitochondrial Dynamics; Mitochondrial Proteins; Resveratrol; Stilbenes | 2017 |
Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway.
Topics: Adenylate Kinase; Animals; Apoptosis; Autophagy; Beclin-1; Caspase 3; Caspase 9; Female; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1; Spinal Cord; Spinal Cord Injuries; Stilbenes | 2017 |
Biorelevant physicochemical profiling of (E)- and (Z)-resveratrol determined from isomeric mixtures.
Topics: Hydrogen-Ion Concentration; Isomerism; Magnetic Resonance Spectroscopy; Octanols; Resveratrol; Solubility; Stilbenes; Water | 2017 |
Preparation Nanocrystals of Poorly Soluble Plant Compounds Using an Ultra-Small-Scale Approach.
Topics: Freeze Drying; Hesperidin; Nanoparticles; Quercetin; Resveratrol; Rutin; Solubility; Stilbenes; Suspensions; Technology, Pharmaceutical | 2017 |
Resveratrol Attenuates Subacute Systemic Inflammation-Induced Spatial Memory Impairment via Inhibition of Astrocyte Activation and Enhancement of Synaptophysin Expression in the Hippocampus.
Topics: Animals; Astrocytes; Blotting, Western; Glial Fibrillary Acidic Protein; Hippocampus; Hyperalgesia; Immunohistochemistry; Inflammation; Lipopolysaccharides; Male; Maze Learning; Memory Disorders; Mice, Inbred ICR; Microglia; Models, Biological; Resveratrol; Sirtuin 1; Spatial Memory; Stilbenes; Synaptophysin | 2017 |
Oral Administration of Resveratrol Alleviates Osteoarthritis Pathology in C57BL/6J Mice Model Induced by a High-Fat Diet.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Blotting, Western; Diet, High-Fat; Enzyme-Linked Immunosorbent Assay; Inflammation; Male; Mice; Mice, Inbred C57BL; Obesity; Osteoarthritis; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stilbenes | 2017 |
Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster.
Topics: Aging; Animals; Dose-Response Relationship, Drug; Drosophila melanogaster; Enzyme Activation; Enzyme Inhibitors; Female; Genotype; Humans; Male; Monocytes; Mutation; Resorcinols; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Resveratrol ameliorates hyperglycemia-induced renal tubular oxidative stress damage via modulating the SIRT1/FOXO3a pathway.
Topics: Animals; Catalase; Cytoprotection; Diabetic Nephropathies; Forkhead Box Protein O3; Hyperglycemia; Kidney Tubules; Male; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2017 |
Peripheral and Cerebral Resistance Arteries in the Spontaneously Hypertensive Heart Failure Rat: Effects of Stilbenoid Polyphenols.
Topics: Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Mesenteric Arteries; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vascular Resistance | 2017 |
Pyridoxine-resveratrol hybrids Mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Chelating Agents; Cholinesterase Inhibitors; Electrophorus; Humans; Kinetics; Mannich Bases; Metals; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pyridoxine; Rats; Resveratrol; Stilbenes | 2017 |
Resveratrol regulates microglia M1/M2 polarization via PGC-1α in conditions of neuroinflammatory injury.
Topics: Animals; Cell Line, Tumor; Cell Polarity; Encephalitis; Humans; Mice; Microglia; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Hairy root culture optimization and resveratrol production from Vitis vinifera subsp. sylvesteris.
Topics: Agrobacterium; Biomass; Coculture Techniques; Culture Media; Cyclopentanes; DNA, Plant; Genotype; In Vitro Techniques; Oxylipins; Plant Roots; Resveratrol; Sodium Acetate; Stilbenes; Vitis | 2017 |
A Focused Multiple Reaction Monitoring (MRM) Quantitative Method for Bioactive Grapevine Stilbenes by Ultra-High-Performance Liquid Chromatography Coupled to Triple-Quadrupole Mass Spectrometry (UHPLC-QqQ).
Topics: Biological Products; Chromatography, High Pressure Liquid; Mass Spectrometry; Phytochemicals; Resveratrol; Stilbenes; Vitis; Wine | 2017 |
Comprehensive Metabolomic Analysis in Blood, Urine, Fat, and Muscle in Men with Metabolic Syndrome: A Randomized, Placebo-Controlled Clinical Trial on the Effects of Resveratrol after Four Months' Treatment.
Topics: Adipose Tissue; Biomarkers; Blood Pressure; Gastrointestinal Microbiome; Humans; Insulin Resistance; Male; Metabolic Syndrome; Metabolomics; Middle Aged; Muscles; Obesity; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2017 |
α-Tocopherol as functional excipient for resveratrol and coenzyme Q10-loaded SNEDDS for improved bioavailability and prophylaxis of breast cancer.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Antioxidants; Area Under Curve; Biological Availability; Breast Neoplasms; Caco-2 Cells; Coumarins; Drug Delivery Systems; Emulsions; Excipients; Female; Humans; Nanoparticles; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thiazoles; Ubiquinone | 2017 |
Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).
Topics: Amino Acid Sequence; Anticarcinogenic Agents; Antioxidants; Apoptosis; Calcium; Calcium Channels; Cancer-Associated Fibroblasts; Cell Line, Tumor; Humans; Male; Mutation; Nerve Tissue Proteins; Prostate; Prostatic Neoplasms; Resveratrol; Stilbenes; Transient Receptor Potential Channels; TRPA1 Cation Channel; Tumor Microenvironment | 2017 |
Resveratrol ameliorates the chemical and microbial induction of inflammation and insulin resistance in human placenta, adipose tissue and skeletal muscle.
Topics: Adipose Tissue; Diabetes, Gestational; Female; Humans; Infant; Inflammation; Insulin; Insulin Resistance; Muscle, Skeletal; Placenta; Pregnancy; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Hydroxystilbenes and methoxystilbenes activate human aryl hydrocarbon receptor and induce CYP1A genes in human hepatoma cells and human hepatocytes.
Topics: Adult; Aged; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inducers; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Isomerism; Male; Middle Aged; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes | 2017 |
Effects of Resveratrol Supplementation on Methotrexate Chemotherapy-Induced Bone Loss.
Topics: Adipocytes; Adipogenesis; Animals; Bone and Bones; Bone Diseases; Dietary Supplements; Dose-Response Relationship, Drug; Male; Methotrexate; Osteoclasts; Osteogenesis; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes | 2017 |
Resveratrol rescues cadmium-induced mitochondrial injury by enhancing transcriptional regulation of PGC-1α and SOD2 via the Sirt3/FoxO3a pathway in TCMK-1 cells.
Topics: Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cadmium; Cells, Cultured; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Forkhead Box Protein O3; Gene Expression Regulation; Immunoblotting; Kidney Tubules; Mice; Mitochondria; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Resveratrol; RNA Interference; Signal Transduction; Sirtuin 3; Stilbenes; Superoxide Dismutase | 2017 |
In vitro cytotoxicity evaluation of resveratrol-loaded nanoparticles: Focus on the challenges of in vitro methodologies.
Topics: Cell Line; Drug Carriers; Humans; Keratinocytes; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Toxicity Tests | 2017 |
Wine Chemical Composition and Radical Scavenging Activity of Some Cabernet Franc Clones.
Topics: Anthocyanins; Color; Free Radical Scavengers; Phenols; Principal Component Analysis; Resveratrol; Serbia; Stilbenes; Tannins; Taste; Vitis; Wine | 2017 |
Evaluation of growth inhibitory response of Resveratrol and Salinomycin combinations against triple negative breast cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cadherins; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Humans; Mice; NF-kappa B; Pyrans; Resveratrol; Stilbenes; Triple Negative Breast Neoplasms | 2017 |
Anti-Cancer Activity of Resveratrol and Derivatives Produced by Grapevine Cell Suspensions in a 14 L Stirred Bioreactor.
Topics: Antineoplastic Agents, Phytogenic; Batch Cell Culture Techniques; Bioreactors; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Plant Cells; Resveratrol; Stilbenes; Vitis | 2017 |
Anti-Tumorigenic Effects of Resveratrol in Lung Cancer Cells Through Modulation of c-FLIP.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Humans; Hydrogen Peroxide; Lung Neoplasms; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells.
Topics: A549 Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cellular Senescence; DNA Replication; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Receptors, Interleukin-8B; Resveratrol; S Phase Cell Cycle Checkpoints; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Co-treatment with indole-3-carbinol and resveratrol modify porcine CYP1A and CYP3A activities and expression.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Food-Drug Interactions; Gene Expression Regulation, Enzymologic; Hepatocytes; Indoles; Male; Microsomes, Liver; Pregnane X Receptor; Receptors, Aryl Hydrocarbon; Receptors, Steroid; Resveratrol; Stilbenes; Swine | 2018 |
Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Female; Inflammation; Lipopolysaccharides; Liver; Male; Mitogen-Activated Protein Kinases; Models, Biological; Pulmonary Edema; Rats; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Transcription Factor RelA | 2017 |
Resveratrol inhibits androgen production of human adrenocortical H295R cells by lowering CYP17 and CYP21 expression and activities.
Topics: Adrenal Cortex; Androgens; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytochrome P450 Family 21; Humans; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Messenger; Sirtuin 3; Steroid 17-alpha-Hydroxylase; Stilbenes | 2017 |
Efficient de novo synthesis of resveratrol by metabolically engineered Escherichia coli.
Topics: Bacterial Proteins; Base Sequence; Culture Media; Escherichia coli; Escherichia coli Proteins; Malonyl Coenzyme A; Metabolic Engineering; Microorganisms, Genetically-Modified; Multienzyme Complexes; Nucleic Acid Conformation; Resveratrol; Stilbenes | 2017 |
The dietary constituent resveratrol suppresses nociceptive neurotransmission via the NMDA receptor.
Topics: Action Potentials; Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glutamic Acid; Hyperalgesia; Iontophoresis; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Resveratrol; Sensory Receptor Cells; Stilbenes; Trigeminal Nucleus, Spinal | 2017 |
Resveratrol Treatment Normalizes the Endothelial Function and Blood Pressure in Ovariectomized Rats.
Topics: Animals; Antioxidants; Blood Pressure; Endothelium, Vascular; Estrogens; Female; Hypertension; Nitrates; Nitric Oxide; Nitrites; Ovariectomy; Rats, Wistar; Reference Values; Reproducibility of Results; Resveratrol; Stilbenes; Time Factors; Treatment Outcome | 2017 |
Caloric Restriction Mimetics Slow Aging of Neuromuscular Synapses and Muscle Fibers.
Topics: Aging; Animals; Antioxidants; Caloric Restriction; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Hypoglycemic Agents; Immunohistochemistry; Metformin; Mice; Mice, Inbred C57BL; Motor Disorders; Muscle Fibers, Skeletal; Neuromuscular Junction; Resveratrol; Stilbenes; Synapses | 2017 |
Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.
Topics: Animals; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Culture Media, Conditioned; Fibroblasts; Humans; Interleukins; Melanoma; Mice; Phenotype; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Tumor Cells, Cultured; Tumor Microenvironment | 2017 |
Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure.
Topics: Acrolein; Allergens; Animals; Antibody Formation; Cytokines; Disease Models, Animal; Forkhead Transcription Factors; Hypersensitivity; Immunologic Factors; Lung; Mice; Neoplasms; NF-kappa B; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; T-Lymphocytes, Regulatory | 2017 |
Generation of Antifungal Stilbenes Using the Enzymatic Secretome of Botrytis cinerea.
Topics: Antifungal Agents; Biotransformation; Botrytis; Fungal Proteins; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oomycetes; Plant Diseases; Resveratrol; Stilbenes; Vitis | 2017 |
Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cell Adhesion; Disease Models, Animal; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Monocytes; p38 Mitogen-Activated Protein Kinases; Peritonitis; Primary Cell Culture; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2017 |
The inhibitory effect of resveratrol on COX-2 expression in human colorectal cancer: a promising therapeutic strategy.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Humans; Resveratrol; RNA, Messenger; Stilbenes | 2017 |
Resveratrol derivative BTM-0512 mitigates obesity by promoting beige remodeling of subcutaneous preadipocytes.
Topics: Adipocytes; Adipose Tissue, Beige; Adipose Tissue, Brown; Animals; Blotting, Western; Body Weight; Cells, Cultured; Diet, High-Fat; DNA-Binding Proteins; Gene Expression; Humans; Male; Mice, Inbred C57BL; Molecular Structure; Obesity; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Sirtuin 1; Stilbenes; Subcutaneous Fat; Transcription Factors; Uncoupling Protein 1 | 2017 |
Dietary resveratrol supplementation prevents transport-stress-impaired meat quality of broilers through maintaining muscle energy metabolism and antioxidant status.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Diet; Dietary Supplements; Energy Metabolism; Male; Meat; Muscle, Skeletal; Random Allocation; Resveratrol; Stilbenes; Stress, Physiological; Transportation | 2017 |
Bioconversion of stilbenes in genetically engineered root and cell cultures of tobacco.
Topics: Biosynthetic Pathways; Cell Culture Techniques; Cytochrome P-450 CYP1B1; Gene Expression Regulation, Plant; Genetic Engineering; Humans; Methyltransferases; Mixed Function Oxygenases; Nicotiana; Plant Proteins; Plant Roots; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis | 2017 |
Resveratrol protects the loss of connexin 43 induced by ethanol exposure in neonatal mouse cardiomyocytes.
Topics: Animals; Animals, Newborn; Antioxidants; Cell Survival; Connexin 43; Ethanol; Mice; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Resveratrol; Stilbenes | 2017 |
Multi-Level Characterization of the Membrane Properties of Resveratrol-Incorporated Liposomes.
Topics: Antioxidants; Cell Membrane; Hydroxyl Radical; Lipid Peroxidation; Liposomes; Membrane Fluidity; Resveratrol; Stilbenes | 2017 |
Differential autophagic effects of vital dyes in retinal pigment epithelial ARPE-19 and photoreceptor 661W cells.
Topics: Animals; Autophagy; Cell Survival; Cells, Cultured; Chloroquine; Coloring Agents; Humans; Indocyanine Green; Lutein; Mice; Protective Agents; Resveratrol; Retinal Pigment Epithelium; Rosaniline Dyes; Stilbenes; Ubiquinone; Vitrectomy | 2017 |
A monoclonal antibody-based immunoassay for the determination of oxyresveratrol from Artocarpus lacucha Buch.-Ham.
Topics: Animals; Antibodies, Monoclonal; Antioxidants; Antiviral Agents; Artocarpus; Enzyme-Linked Immunosorbent Assay; Immunization; Immunoassay; Male; Mice, Inbred BALB C; Monophenol Monooxygenase; Plant Extracts; Reproducibility of Results; Resveratrol; Stilbenes | 2017 |
Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells.
Topics: Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Cell Cycle; Cell Line, Tumor; DNA Damage; Drug Synergism; Humans; Membrane Potential, Mitochondrial; Nitrophenols; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Sulfonamides; Tumor Suppressor Protein p53 | 2017 |
Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism.
Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Animals; Anti-Inflammatory Agents; Biological Availability; Cell Survival; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Inflammation; Injections, Intravenous; Male; Molecular Structure; Pulmonary Disease, Chronic Obstructive; Rats; Rats, Sprague-Dawley; Respiratory System; Resveratrol; Stilbenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2017 |
Extremely low-frequency electromagnetic field exposure enhances inflammatory response and inhibits effect of antioxidant in RAW 264.7 cells.
Topics: Animals; Antioxidants; Cytokines; Down-Regulation; Electromagnetic Fields; Gene Knockdown Techniques; Homeodomain Proteins; Homeostasis; Inflammation; Mice; NF-kappa B; NFATC Transcription Factors; RAW 264.7 Cells; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Rapid assay of resveratrol in red wine by paper spray tandem mass spectrometry and isotope dilution.
Topics: Isotopes; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Wine | 2017 |
Resveratrol protects podocytes against apoptosis via stimulation of autophagy in a mouse model of diabetic nephropathy.
Topics: Albuminuria; Animals; Apoptosis; Autophagy; Diabetic Nephropathies; Disease Models, Animal; Mice; Mice, Inbred C57BL; Podocytes; Protective Agents; Resveratrol; RNA, Small Interfering; Stilbenes | 2017 |
Are miRNA-103, miRNA-107 and miRNA-122 Involved in the Prevention of Liver Steatosis Induced by Resveratrol?
Topics: Animals; Carnitine O-Palmitoyltransferase; Cell Line; Diet, High-Fat; Down-Regulation; Fatty Acid Synthases; Fatty Liver; Hepatocytes; Liver; Male; MicroRNAs; Rats; Rats, Sprague-Dawley; Resveratrol; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2017 |
Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cyclin D1; Hepatitis B virus; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Repressor Proteins; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Survivin; Trans-Activators; Viral Regulatory and Accessory Proteins | 2017 |
Resveratrol inhibits LPS-induced mice mastitis through attenuating the MAPK and NF-κB signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cytokines; Disease Models, Animal; Female; Inflammation; Interleukin-1beta; Lipopolysaccharides; Mammary Glands, Animal; MAP Kinase Signaling System; Mastitis; Mice; Mice, Inbred BALB C; NF-kappa B; Peroxidase; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
Skin permeation and antioxidant efficacy of topically applied resveratrol.
Topics: Administration, Cutaneous; Adult; Animals; Biphenyl Compounds; Epidermis; Female; Free Radical Scavengers; Free Radicals; Healthy Volunteers; Humans; Permeability; Picrates; Resveratrol; Skin Absorption; Spectrum Analysis, Raman; Stilbenes; Sus scrofa; Treatment Outcome | 2017 |
Effects of dietary resveratrol supplementation on hepatic and serum pro-/anti-inflammatory activity in juvenile GIFT tilapia, Oreochromis niloticus.
Topics: Animals; Anti-Inflammatory Agents; Cichlids; Cytokines; Dietary Supplements; Immunoglobulin M; Liver; Resveratrol; Stilbenes | 2017 |
Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells.
Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; Cell Survival; Curcumin; Gene Expression Regulation, Neoplastic; Humans; Male; Melatonin; Prostatic Neoplasms; Reactive Oxygen Species; Resveratrol; Silybin; Silymarin; Stilbenes; Thioredoxins | 2017 |
Resveratrol attenuates skeletal muscle atrophy induced by chronic kidney disease via MuRF1 signaling pathway.
Topics: Animals; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscular Atrophy; NF-kappa B; Renal Insufficiency, Chronic; Resveratrol; Signal Transduction; Stilbenes; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2017 |
Folic acid-functionalized drug delivery platform of resveratrol based on Pluronic 127/D-α-tocopheryl polyethylene glycol 1000 succinate mixed micelles.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Magnetic Resonance Spectroscopy; MCF-7 Cells; Micelles; Poloxamer; Polyethylene Glycols; Rats, Sprague-Dawley; Resveratrol; Spectrophotometry, Infrared; Stilbenes; Tissue Distribution; Vitamin E | 2017 |
Assessment of the potential activity of major dietary compounds as selective estrogen receptor modulators in two distinct cell models for proliferation and differentiation.
Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents, Phytogenic; Apigenin; Breast Neoplasms; Cell Proliferation; Chemokine CXCL12; Diet; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Isoflavones; MCF-7 Cells; Nerve Tissue Proteins; Neurites; Neurogenesis; PC12 Cells; Pheochromocytoma; Phytoestrogens; Rats; Response Elements; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes; Transcription, Genetic; Transfection; Zearalenone | 2017 |
Alginate Nanoparticles Containing Curcumin and Resveratrol: Preparation, Characterization, and In Vitro Evaluation Against DU145 Prostate Cancer Cell Line.
Topics: Alginates; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Liberation; Glucuronic Acid; Hexuronic Acids; Humans; Male; Nanoparticles; Particle Size; Prostatic Neoplasms; Resveratrol; Stilbenes | 2017 |
Resveratrol induces mitochondrial dysfunction and decreases chronological life span of Saccharomyces cerevisiae in a glucose-dependent manner.
Topics: Antioxidants; Glucose; Hydrogen Peroxide; Longevity; Mitochondria; Oxidative Phosphorylation; Oxygen Consumption; Resveratrol; Saccharomyces cerevisiae; Stilbenes | 2017 |
Dominant Carbons in trans- and cis-Resveratrol Isomerization.
Topics: Carbon; Isomerism; Quantum Theory; Resveratrol; Static Electricity; Stilbenes | 2017 |
Lycopene and resveratrol pretreatment did not interfere with the liver of hepatectomized rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Carotenoids; Hepatectomy; Liver; Liver Regeneration; Lycopene; Male; Mitotic Index; Oxidative Stress; Rats, Wistar; Reproducibility of Results; Resveratrol; Stilbenes; Time Factors; Treatment Outcome | 2017 |
Resveratrol reduces the apoptosis induced by cigarette smoke extract by upregulating MFN2.
Topics: Apoptosis; Bronchi; Cells, Cultured; Complex Mixtures; Epithelial Cells; GTP Phosphohydrolases; Humans; Mitochondria; Mitochondrial Proteins; Respiratory Mucosa; Resveratrol; Stilbenes; Tobacco Smoke Pollution; Up-Regulation | 2017 |
Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice.
Topics: Adipose Tissue; Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blood Glucose; Body Weight; Drug Combinations; Drug Evaluation, Preclinical; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose Tolerance Test; Insulin Resistance; Liver; Male; Mice, Mutant Strains; Organ Size; Oxidative Stress; Resveratrol; Stilbenes; Vitamin D | 2017 |
Development and evaluation of resveratrol, Vitamin E, and epigallocatechin gallate loaded lipid nanoparticles for skin care applications.
Topics: Catechin; Drug Evaluation, Preclinical; Female; Humans; Lipid Metabolism; Lipids; Middle Aged; Nanoparticles; Organ Culture Techniques; Resveratrol; Skin; Skin Care; Stilbenes; Vitamin E | 2017 |
During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.
Topics: Acetylation; Gene Expression Regulation, Fungal; Microbial Viability; Phenotype; Phosphoenolpyruvate Carboxykinase (GTP); Resveratrol; Saccharomyces cerevisiae; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 2; Stilbenes | 2017 |
Resveratrol alleviates FFA and CCl4 induced apoptosis in HepG2 cells via restoring endoplasmic reticulum stress.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Biomarkers; Cytokines; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fatty Acids, Nonesterified; Gene Silencing; Heat-Shock Proteins; Hep G2 Cells; Humans; Inflammation Mediators; Resveratrol; Stilbenes | 2017 |
Spectroscopic evidences of toxic trans-crotonaldehyde trapped and transformed by resveratrol to prevent the damage of mitochondrial DNA.
Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; DNA Damage; DNA, Mitochondrial; Hydrogen-Ion Concentration; Male; Mitochondria; Models, Molecular; Rats, Wistar; Resveratrol; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Stilbenes | 2017 |
Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia.
Topics: Animals; Antioxidants; Brain-Derived Neurotrophic Factor; Dementia, Vascular; Disease Models, Animal; Drug Therapy, Combination; Glutathione; Hippocampus; Interleukin-1beta; Male; Malondialdehyde; Maze Learning; Melatonin; Memory Disorders; Models, Molecular; Rats; Rats, Wistar; Recognition, Psychology; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Thioredoxin-Interacting Protein Mediates Apoptosis in Early Brain Injury after Subarachnoid Haemorrhage.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Injuries; Carrier Proteins; Cell Cycle Proteins; eIF-2 Kinase; Gene Expression; Male; Neurons; Permeability; Protein Binding; Protein Transport; Rats; Resveratrol; RNA, Small Interfering; Stilbenes; Subarachnoid Hemorrhage | 2017 |
Resveratrol suppresses hyperoxia-induced nucleocytoplasmic shuttling of SIRT1 and ROS production in PBMC from preterm infants in vitro.
Topics: Active Transport, Cell Nucleus; Cells, Cultured; Female; Humans; Hyperoxia; Infant, Newborn; Infant, Premature; Leukocytes, Mononuclear; Malondialdehyde; Oxygen; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Ultrasound processed nanoemulsion: A comparative approach between resveratrol and resveratrol cyclodextrin inclusion complex to study its binding interactions, antioxidant activity and UV light stability.
Topics: Animals; Antioxidants; Cattle; Cyclodextrins; Emulsions; Hydrogen-Ion Concentration; Nanotechnology; Particle Size; Resveratrol; Serum Albumin, Bovine; Sonication; Stilbenes; Surface Tension; Thermodynamics; Ultrasonic Waves; Ultraviolet Rays; Viscosity | 2017 |
Anticancer effects of novel resveratrol analogues on human ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; Female; Humans; Interleukin-6; Ovarian Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol protects against early polymicrobial sepsis-induced acute kidney injury through inhibiting endoplasmic reticulum stress-activated NF-κB pathway.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Biomarkers; Cell Line; Cytokines; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; Inflammation Mediators; Kidney Function Tests; Lipopolysaccharides; Male; Membrane Proteins; NF-kappa B; Protein Serine-Threonine Kinases; Rats; Resveratrol; Sepsis; Signal Transduction; Stilbenes | 2017 |
Multiple repair pathways mediate cellular tolerance to resveratrol-induced DNA damage.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chickens; Chromosome Aberrations; DNA Breaks, Double-Stranded; DNA Repair; Histones; Resveratrol; Stilbenes | 2017 |
Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Disease Models, Animal; Gene Expression Regulation; Kidney; Male; Mice; Mitochondria; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Resveratrol; Stilbenes | 2017 |
A genomics approach identifies selective effects of trans-resveratrol in cerebral cortex neuron and glia gene expression.
Topics: Animals; Cell Line; Cerebral Cortex; Down-Regulation; Gene Expression; Genomics; Mice; Neuroglia; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes; Up-Regulation | 2017 |
Binding of resveratrol to the minor groove of DNA sequences with AATT and TTAA segments induces differential stability.
Topics: Base Sequence; Binding Sites; Circular Dichroism; DNA; Molecular Docking Simulation; Nucleic Acid Conformation; Resveratrol; Spectrometry, Fluorescence; Stilbenes | 2017 |
Resveratrol protects against oxidized low‑density lipoprotein‑induced human umbilical vein endothelial cell apoptosis via inhibition of mitochondrial‑derived oxidative stress.
Topics: Apoptosis; Human Umbilical Vein Endothelial Cells; Humans; Lipoproteins, LDL; Mitochondria; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
Expression of mTOR/70S6K signaling pathway in pathological scar fibroblasts and the effects of resveratrol intervention.
Topics: Cicatrix; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Male; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspartate Aminotransferases; Cartilage; Curcumin; Cytokines; Drug Combinations; Edema; Female; Inflammation; Joints; Kidney; Liver; Male; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Pyrazines; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2017 |
Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway.
Topics: Acrylamides; AMP-Activated Protein Kinases; Animals; Carbazoles; Cell Line; Cytokines; Diet, High-Fat; Enzyme Inhibitors; Gene Expression Regulation; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Mice; Mice, Inbred C57BL; NAD; Nicotinamide Mononucleotide; Nicotinamide Phosphoribosyltransferase; Non-alcoholic Fatty Liver Disease; Oleic Acid; Piperidines; Resveratrol; Signal Transduction; Sirtuin 1; Sterol Regulatory Element Binding Protein 1; Stilbenes | 2017 |
Caffeic acid phenethyl ester attenuates pathological cardiac hypertrophy by regulation of MEK/ERK signaling pathway in vivo and vitro.
Topics: Animals; Blotting, Western; Caffeic Acids; Cardiomegaly; Cell Line; Disease Models, Animal; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Phenylephrine; Phenylethyl Alcohol; Polymerase Chain Reaction; Rats; Resveratrol; Smad Proteins; Stilbenes; Transforming Growth Factor beta | 2017 |
Antioxidant capacity of trans-resveratrol dietary supplements alone or combined with the mycotoxin beauvericin.
Topics: Antioxidants; Depsipeptides; Dietary Supplements; Mycotoxins; Resveratrol; Stilbenes | 2017 |
Cytochrome c and resveratrol preserve platelet function during cold storage.
Topics: Blood Platelets; Blood Preservation; Cell Survival; Cryopreservation; Cytochromes c; Humans; Lipid Peroxidation; Mitochondria; Oxygen Consumption; Platelet Activation; Platelet Aggregation; Platelet Count; Platelet Function Tests; Platelet Transfusion; Resveratrol; Stilbenes; Thrombelastography | 2017 |
Resveratrol inhibits hepatocellular carcinoma progression driven by hepatic stellate cells by targeting Gli-1.
Topics: Carcinoma, Hepatocellular; Disease Progression; Hep G2 Cells; Hepatic Stellate Cells; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; Liver Neoplasms; Neoplasm Invasiveness; Neovascularization, Pathologic; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A; Zinc Finger Protein GLI1 | 2017 |
Neuroprotective effect of resveratrol against late cerebral ischemia reperfusion induced oxidative stress damage involves upregulation of osteopontin and inhibition of interleukin-1beta.
Topics: Animals; bcl-2-Associated X Protein; Brain Ischemia; Catalase; Cerebral Cortex; Chemokine CXCL2; Chemokines; Glutathione Peroxidase; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Neuroprotective Agents; Nitric Oxide Synthase Type II; Osteopontin; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes; Superoxide Dismutase; Up-Regulation | 2017 |
Wound healing effects of collagen-laminin dermal matrix impregnated with resveratrol loaded hyaluronic acid-DPPC microparticles in diabetic rats.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Cutaneous; Animals; Cattle; Collagen; Diabetes Mellitus, Experimental; Drug Carriers; Hyaluronic Acid; Laminin; Male; Microspheres; Rats; Rats, Wistar; Resveratrol; Skin; Stilbenes; Treatment Outcome; Wound Healing | 2017 |
Inhibition of NF-κB/TNF-α pathway may be involved in the protective effect of resveratrol against cyclophosphamide-induced multi-organ toxicity.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Blood Urea Nitrogen; Creatine Kinase; Creatinine; Cyclophosphamide; Inflammation; Male; Malondialdehyde; NF-kappa B; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Nanoparticle-mediated dual delivery of resveratrol and DAP5 ameliorates kidney ischemia/reperfusion injury by inhibiting cell apoptosis and inflammation.
Topics: Animals; Apoptosis; Biomarkers; Calcium; Caspase 3; Cell Line; Cell Survival; Cytokines; Disease Models, Animal; Drug Delivery Systems; Humans; Inflammation Mediators; Kidney Diseases; Kidney Function Tests; Male; Nanoparticles; Oxidative Stress; Protective Agents; Rats; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Stilbenes | 2017 |
Studies on Trans-Resveratrol/Carboxymethylated (1,3/1,6)-β-d-Glucan Association for Aerosol Pharmaceutical Applications.
Topics: Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; beta-Glucans; Cell Survival; HeLa Cells; Humans; Nasal Mucosa; Nebulizers and Vaporizers; Particle Size; Resveratrol; Rhinovirus; Stilbenes; Volatilization | 2017 |
Tonic suppression of PCAT29 by the IL-6 signaling pathway in prostate cancer: Reversal by resveratrol.
Topics: Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Interleukin-6; Male; MicroRNAs; Prostatic Neoplasms; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Long Noncoding; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2017 |
Resveratrol Reactivates Latent HIV through Increasing Histone Acetylation and Activating Heat Shock Factor 1.
Topics: Acetylation; Cell Line; Heat-Shock Proteins; Histones; HIV Infections; HIV-1; Humans; Resveratrol; Stilbenes; Virus Latency | 2017 |
Neuroprotective effect of resveratrol on rotenone-treated C57BL/6 mice.
Topics: Animals; Disease Models, Animal; Dopaminergic Neurons; Insecticides; Iron; Male; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neuroprotective Agents; Psychomotor Disorders; Random Allocation; Resveratrol; Rotarod Performance Test; Rotenone; Stilbenes; Substantia Nigra; Tyrosine 3-Monooxygenase | 2017 |
Co-encapsulated resveratrol and quercetin in chitosan and peg modified chitosan nanoparticles: For efficient intra ocular pressure reduction.
Topics: Animals; Antioxidants; Chickens; Chitosan; Drug Carriers; Drug Compounding; Drug Liberation; Hydrogen-Ion Concentration; Intraocular Pressure; Nanoparticles; Osmolar Concentration; Particle Size; Polyethylene Glycols; Quercetin; Rabbits; Resveratrol; Spectroscopy, Fourier Transform Infrared; Stilbenes | 2017 |
[Effect of resveratrol on expression of TLR4 and inflammatory factors in gingival epithelial cells under high glucose environment].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cells, Cultured; Epithelial Cells; Gingiva; Glucose; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; NF-kappa B; Periodontitis; Resveratrol; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2017 |
RES-loaded pegylated CS NPs: for efficient ocular delivery.
Topics: Administration, Ophthalmic; Angiogenesis Inhibitors; Animals; Chitosan; Coated Materials, Biocompatible; Cornea; Delayed-Action Preparations; Diffusion; In Vitro Techniques; Nanocapsules; Ocular Absorption; Particle Size; Polyethylene Glycols; Rabbits; Resveratrol; Stilbenes | 2017 |
Inflammation Downregulates UCP1 Expression in Brown Adipocytes Potentially via SIRT1 and DBC1 Interaction.
Topics: Adipocytes, Brown; Animals; Cell Cycle Proteins; Cell Line; Down-Regulation; Inflammation; Interleukin-1beta; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Resveratrol; Sirtuin 1; Stilbenes; Uncoupling Protein 1 | 2017 |
Mechanism of resveratrol-induced relaxation in the human gallbladder.
Topics: Adult; Aged; Aged, 80 and over; Animals; Female; Gallbladder; Guinea Pigs; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channels; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents; Young Adult | 2017 |
Thioredoxin-interacting protein links endoplasmic reticulum stress to inflammatory brain injury and apoptosis after subarachnoid haemorrhage.
Topics: Adenine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood-Brain Barrier; Brain Edema; Carrier Proteins; Cell Cycle Proteins; Encephalitis; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Gene Expression Regulation; Indoles; Male; Models, Biological; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Subarachnoid Hemorrhage; Sulfonamides; Thiophenes | 2017 |
Resveratrol Inhibits Periodontitis-Related Bone Loss in Rats Subjected to Cigarette Smoke Inhalation.
Topics: Alveolar Bone Loss; Animals; Cytokines; Disease Models, Animal; Disease Progression; Gene Expression; Immunologic Factors; Inflammation Mediators; Male; Periodontitis; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Smoking; Stilbenes | 2017 |
Resveratrol Protects Against Pulmonary Arterial Hypertension in Rats via Activation of Silent Information Regulator 1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood Pressure; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Down-Regulation; Heterocyclic Compounds, 4 or More Rings; Hypertension, Pulmonary; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Vascular Remodeling | 2017 |
Negative correlation between serum uric acid and kidney URAT1 mRNA expression caused by resveratrol in rats.
Topics: Alanine Transaminase; Allopurinol; Animals; Anion Transport Proteins; Aspartate Aminotransferases; C-Reactive Protein; Creatinine; Cytokines; Disease Models, Animal; Hyperuricemia; Kidney; Male; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Uric Acid | 2017 |
Activity of resveratrol triesters against primary acute lymphoblastic leukemia cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; G1 Phase Cell Cycle Checkpoints; Humans; Molecular Structure; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Resveratrol; Stilbenes; Structure-Activity Relationship | 2017 |
Resveratrol promotes recovery of immune function of immunosuppressive mice by activating JNK/NF-κB pathway in splenic lymphocytes.
Topics: Animals; Female; I-kappa B Kinase; Immunosuppression Therapy; JNK Mitogen-Activated Protein Kinases; Lymphocytes; Male; MAP Kinase Signaling System; Mice; NF-kappa B; Recovery of Function; Resveratrol; Spleen; Stilbenes; Up-Regulation | 2017 |
Biomimetic Synthesis of Resveratrol Trimers Catalyzed by Horseradish Peroxidase.
Topics: Benzofurans; Biocatalysis; Biomimetics; Horseradish Peroxidase; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Resveratrol; Stilbenes | 2017 |
Anti-oxidative effect of resveratrol on aluminum induced toxicity in rat cerebral tissue.
Topics: Aluminum Compounds; Animals; Antioxidants; Brain; Lipid Peroxidation; Male; Nerve Degeneration; Neuroglia; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Mechanism of As2O3-Induced Action Potential Prolongation and Using hiPS-CMs to Evaluate the Rescue Efficacy of Drugs With Different Rescue Mechanism.
Topics: Action Potentials; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; ERG1 Potassium Channel; HEK293 Cells; Humans; Induced Pluripotent Stem Cells; Leukemia, Promyelocytic, Acute; Long QT Syndrome; Lysosomes; Myocytes, Cardiac; Oxides; Patch-Clamp Techniques; Proteolysis; Resveratrol; Stilbenes; Terfenadine | 2017 |
Role of sulfotransferases in resveratrol metabolism in human adipocytes.
Topics: Adipocytes; Arylsulfotransferase; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Gene Silencing; Humans; Polyphenols; Resveratrol; Stilbenes; Up-Regulation | 2017 |
Functional Mitochondria Are Important for the Effect of Resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Size; DNA, Mitochondrial; HeLa Cells; Humans; Mitochondria; Organ Specificity; Osteoblasts; Oxygen Consumption; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Sirt1 ameliorates systemic sclerosis by targeting the mTOR pathway.
Topics: Animals; Biopsy; Bleomycin; Cells, Cultured; Collagen; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fibroblasts; Gene Knockdown Techniques; Humans; Immunohistochemistry; Mice; Mice, Inbred C3H; Phosphorylation; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Scleroderma, Systemic; Signal Transduction; Sirolimus; Sirtuin 1; Skin; Stilbenes; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Morphogenetic Protein 7; Cell Proliferation; Cell Survival; Colonic Neoplasms; Flow Cytometry; HCT116 Cells; Humans; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2017 |
Resveratrol may reverse the effects of long-term occupational exposure to electromagnetic fields on workers of a power plant.
Topics: Biomarkers; Cytokines; Dietary Supplements; Electromagnetic Fields; Female; Humans; Inflammation Mediators; Male; Occupational Exposure; Oxidative Stress; Power Plants; Radiation-Protective Agents; Resveratrol; Risk Factors; Stilbenes | 2017 |
SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2.
Topics: Animals; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Male; Mice; Mice, Inbred C57BL; Osteoblasts; Osteogenesis; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2017 |
Resveratrol relieves Angiostrongylus cantonensis - Induced meningoencephalitis by activating sirtuin-1.
Topics: Angiostrongylus cantonensis; Animals; Blood-Brain Barrier; Cytokines; Gene Expression Regulation; Male; Meningoencephalitis; Mice; Resveratrol; Sirtuin 1; Stilbenes; Strongylida Infections | 2017 |
Resveratrol alleviates oxidative damage in enteric neurons and associated gastrointestinal dysfunction caused by chemotherapeutic agent oxaliplatin.
Topics: Animals; Antineoplastic Agents; Antioxidants; Colon; Gastrointestinal Diseases; Intestinal Mucosa; Male; Mice, Inbred BALB C; Neurons; Organoplatinum Compounds; Oxaliplatin; Oxidative Stress; Resveratrol; Stilbenes | 2017 |
Resveratrol beneficially affects meat quality of heat-stressed broilers which is associated with changes in muscle antioxidant status.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Chickens; Corticosterone; Diet; Dietary Supplements; Food Quality; Glutathione Peroxidase; Hot Temperature; Male; Malondialdehyde; Meat; Muscles; Resveratrol; Stilbenes; Stress, Physiological; Time Factors; Triglycerides | 2017 |
Resveratrol induces membrane and DNA disruption via pro-oxidant activity against Salmonella typhimurium.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Survival; DNA, Bacterial; Microbial Sensitivity Tests; Oxidants; Oxidation-Reduction; Oxidative Stress; Resveratrol; Salmonella typhimurium; Stilbenes; Structure-Activity Relationship | 2017 |
The metal nanoparticle-induced inflammatory response is regulated by SIRT1 through NF-κB deacetylation in aseptic loosening.
Topics: Acetylation; Aged, 80 and over; Animals; Arthroplasty, Replacement, Hip; Cytokines; Female; Humans; Inflammation; Macrophages; Male; Metal Nanoparticles; Mice, Inbred C57BL; Middle Aged; NF-kappa B; Osteolysis; Prostheses and Implants; Prosthesis Failure; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Identification of tissue-specific transcriptional markers of caloric restriction in the mouse and their use to evaluate caloric restriction mimetics.
Topics: 2,4-Dinitrophenol; Adipose Tissue, White; Aging; Animals; Bezafibrate; Caloric Restriction; Carnitine; Citrate (si)-Synthase; Gene Expression Profiling; Gene Expression Regulation; Glycated Hemoglobin; Interferon-gamma; Male; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Muscle, Skeletal; Myocardium; Neocortex; Pioglitazone; Quercetin; Resveratrol; Sirtuin 3; Stilbenes; Thiazolidinediones; Tumor Necrosis Factor-alpha | 2017 |
Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism.
Topics: Albumins; Ammonia; Carbamoyl-Phosphate Synthase (Ammonia); CCAAT-Enhancer-Binding Proteins; Cell Line, Transformed; CRISPR-Cas Systems; Cytochrome P-450 Enzyme System; Founder Effect; Gene Editing; Gene Expression Regulation; Genes, Reporter; Hep G2 Cells; Hepatocyte Nuclear Factor 4; High-Throughput Screening Assays; Humans; Inactivation, Metabolic; Liver, Artificial; Luminescent Proteins; Phenylbutyrates; Red Fluorescent Protein; Resveratrol; Small Molecule Libraries; Stilbenes; Urea | 2017 |
Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat.
Topics: Animals; Anthocyanins; Biological Availability; Blood Glucose; Brain; Catechin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Flavonoids; Grape Seed Extract; Male; Polyphenols; Quercetin; Rats; Rats, Zucker; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Vitis | 2017 |
Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death.
Topics: A549 Cells; Apoptosis; Autophagy; Gene Knockdown Techniques; Glucosylceramidase; HT29 Cells; Humans; Lysosomes; Necrosis; Resveratrol; RNA Interference; Signal Transduction; Sphingolipids; Stilbenes | 2017 |
In vitro and in vivo evaluation of cubosomal in situ nasal gel containing resveratrol for brain targeting.
Topics: Administration, Intranasal; Brain; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Liberation; Gels; Glycerides; Particle Size; Poloxamer; Polymers; Resveratrol; Stilbenes; Tissue Distribution | 2017 |
Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.
Topics: Analgesics; Animals; Calcium Channels; Ganglia, Spinal; HEK293 Cells; Humans; Inhibitory Concentration 50; Nerve Tissue Proteins; Pain; Patch-Clamp Techniques; Rats; Resveratrol; Stilbenes; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2017 |
Anticonvulsant activity of resveratrol-loaded liposomes in vivo.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Drug Carriers; Electrocorticography; Epilepsy; Glutathione; Glutathione Transferase; Liposomes; Male; Malondialdehyde; Penicillins; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
Identification of endocrine disrupting chemicals acting on human aromatase.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles | 2018 |
Resveratrol protects against L-arginine-induced acute necrotizing pancreatitis in mice by enhancing SIRT1-mediated deacetylation of p53 and heat shock factor 1.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Heat Shock Transcription Factors; Male; Mice; Mice, Inbred BALB C; Pancreatitis, Acute Necrotizing; Protein Interaction Maps; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Depigmenting Effect of Resveratrol Is Dependent on FOXO3a Activation without SIRT1 Activation.
Topics: Cell Line, Tumor; Forkhead Box Protein O3; Humans; Melanins; Melanocytes; Monophenol Monooxygenase; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Skin Lightening Preparations; Stilbenes; Superoxide Dismutase | 2017 |
Testing of resveratrol microemulsion photostability and protective effect against UV induced oxidative stress.
Topics: Cell Line; Drug Delivery Systems; Drug Stability; Emulsions; Humans; Keratinocytes; Oxidative Stress; Resveratrol; Stilbenes; Ultraviolet Rays | 2017 |
The effect of resveratrol, its naturally occurring derivatives and tannic acid on the induction of cell cycle arrest and apoptosis in rat C6 and human T98G glioma cell lines.
Topics: Adjuvants, Pharmaceutic; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioma; Humans; Membrane Potential, Mitochondrial; Rats; Resveratrol; Stilbenes; Tannins | 2017 |
Trans-resveratrol enriched maternal diet protects the immature hippocampus from perinatal asphyxia in rats.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Dietary Supplements; Disease Models, Animal; Epigenesis, Genetic; Female; Hippocampus; Inflammation; Neuroprotective Agents; Pregnancy; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Antioxidants; Cell Culture Techniques; Humans; Neurites; Neurons; Neuroprotective Agents; Oxidative Stress; Plant Extracts; Prenylation; Resveratrol; Stilbenes | 2017 |
Modification of mitochondrial function, cytoplasmic lipid content and cryosensitivity of bovine embryos by resveratrol.
Topics: Animals; Blastocyst; Cattle; Cell Survival; Cells, Cultured; Cryopreservation; Culture Media; Cytoplasm; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; Lipid Metabolism; Lipids; Male; Mitochondria; Resveratrol; Stilbenes | 2017 |
Resveratrol Improves Cell Cycle Arrest in Chronic Prostatitis Rats, by C-kit/SCF Suppression.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Proliferation; Chronic Disease; Diphtheria-Tetanus-Pertussis Vaccine; Disease Models, Animal; Down-Regulation; Humans; Immunohistochemistry; Male; Prostatitis; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Staining and Labeling; Stem Cell Factor; Stilbenes | 2017 |
A novel resveratrol-salinomycin combination sensitizes ER-positive breast cancer cells to apoptosis.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Drug Therapy, Combination; Female; Gene Expression Regulation, Neoplastic; Humans; Pyrans; Receptors, Estrogen; Resveratrol; Signal Transduction; Stilbenes; Wnt Proteins | 2017 |
Potential chemoprotective role of resveratrol against cisplatin induced testicular damage in mice.
Topics: Animals; Antineoplastic Agents; Body Weight; Cisplatin; Injections, Intraperitoneal; Lipid Peroxidation; Male; Mice; Organ Size; Protective Agents; Resveratrol; Spermatozoa; Stilbenes; Structure-Activity Relationship; Testis | 2017 |
Divergent antiarrhythmic effects of resveratrol and piceatannol in a whole-heart model of long QT syndrome.
Topics: Animals; Anti-Arrhythmia Agents; Female; Heart; Isolated Heart Preparation; Long QT Syndrome; Rabbits; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol-loaded glycyrrhizic acid-conjugated human serum albumin nanoparticles wrapping resveratrol nanoparticles: Preparation, characterization, and targeting effect on liver tumors.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Glycyrrhizic Acid; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Mice; Nanoparticles; Resveratrol; Serum Albumin, Human; Stilbenes | 2017 |
Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells.
Topics: Animals; Chemokines; Cytokines; Endothelial Cells; Humans; Inflammation; Macrophages; Mice; Monocytes; RAW 264.7 Cells; Resveratrol; Stilbenes | 2017 |
Research on the protective effects of antioxidants on metabolic syndrome induced by thyroid dysfunction.
Topics: Adult; Anthropometry; Antioxidants; Biomarkers; Cross-Sectional Studies; Female; Humans; Hypothyroidism; Male; Metabolic Syndrome; Middle Aged; Oxidative Stress; Quercetin; Resveratrol; Stilbenes; Thioctic Acid; Thyroid Function Tests; Thyroid Hormones; Thyrotropin | 2017 |
Plant-derived antifungal compounds trigger a common transcriptional response.
Topics: Antifungal Agents; Biphenyl Compounds; Coumarins; Gene Expression Profiling; Gene Expression Regulation, Fungal; Lignans; Oxidative Stress; Plant Extracts; Resveratrol; Schizosaccharomyces; Stilbenes; Transcription, Genetic; Up-Regulation | 2017 |
Pterostilbene Inhibits Lipogenic Activity similar to Resveratrol or Caffeine but Differently Modulates Lipolysis in Adipocytes.
Topics: 3T3 Cells; Adipocytes; Adult; Animals; Biological Transport; Caffeine; Cell Differentiation; Female; Glucose; Glycerol; Humans; Insulin; Lipogenesis; Lipolysis; Mice; Middle Aged; Obesity; Resveratrol; Stilbenes | 2017 |
Resveratrol suppresses pulmonary tumor metastasis by inhibiting platelet-mediated angiogenic responses.
Topics: A549 Cells; Adenosine Diphosphate; Animals; Antineoplastic Agents, Phytogenic; Blood Platelets; Calcium; Cell Adhesion Molecules; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Lung Neoplasms; Mice, Nude; Microfilament Proteins; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphoproteins; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2017 |
Neuro-Protective Effects of Resveratrol on Carbon Monoxide-Induced Toxicity in Male Rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Brain; Carbon Monoxide Poisoning; Lipid Peroxidation; Male; Necrosis; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Evaluation of urinary resveratrol as a biomarker of dietary resveratrol intake in the European Prospective Investigation into Cancer and Nutrition (EPIC) study.
Topics: Biomarkers; Cross-Sectional Studies; Diet; Diet Surveys; Europe; Feeding Behavior; Female; Humans; Male; Mental Recall; Middle Aged; Phenols; Prospective Studies; Resveratrol; Stilbenes; Wine | 2017 |
Application of open-access databases to determine functional connectivity between resveratrol-binding protein QR2 and colorectal carcinoma.
Topics: Colorectal Neoplasms; Databases as Topic; Gene Expression Regulation, Neoplastic; Humans; Open Access Publishing; Quinone Reductases; Resveratrol; Stilbenes | 2017 |
Antitumor activity of resveratrol is independent of Cu(II) complex formation in MCF-7 cell line.
Topics: Antineoplastic Agents; Apoptosis; Coordination Complexes; Copper; Humans; MCF-7 Cells; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Resveratrol alleviates inflammatory hyperalgesia by modulation of reactive oxygen species (ROS), antioxidant enzymes and ERK activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Freund's Adjuvant; Hyperalgesia; Inflammation; MAP Kinase Signaling System; Pain Measurement; Rats; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Resveratrol; Stilbenes | 2017 |
Resveratrol Improved the Progression of Chronic Prostatitis via the Downregulation of c-kit/SCF by Activating Sirt1.
Topics: Animals; Disease Progression; Down-Regulation; Humans; Male; Prostatitis; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1; Stem Cell Factor; Stilbenes | 2017 |
Effect of the Biphenyl Neolignan Honokiol on Aβ
Topics: Amyloid beta-Peptides; Animals; Biphenyl Compounds; Caenorhabditis elegans; Catechin; Chelating Agents; Cholinesterase Inhibitors; Drug Stability; Free Radical Scavengers; Humans; Iron; Lignans; Molecular Docking Simulation; Molecular Structure; Neuroprotective Agents; Paralysis; Peptide Fragments; Picrates; Protein Aggregation, Pathological; Protein Multimerization; Resveratrol; Stilbenes | 2017 |
Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene.
Topics: CD4-Positive T-Lymphocytes; Cells, Cultured; DNA Replication; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Resveratrol; Reverse Transcription; Stilbenes; Viral Proteins; Virus Replication | 2017 |
The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans.
Topics: Aged; Anti-Obesity Agents; Area Under Curve; Body Mass Index; Dietary Supplements; Female; Fruit; Fruit and Vegetable Juices; Humans; Kinetics; Male; Middle Aged; Obesity; Overweight; Pilot Projects; Plant Extracts; Polyphenols; Resveratrol; Seeds; Stilbenes; Vitis | 2017 |
Resveratrol inhibits hypoxia-induced proliferation and migration of pulmonary artery vascular smooth muscle cells by inhibiting the phosphoinositide 3-kinase/protein kinase B signaling pathway.
Topics: Animals; Cell Hypoxia; Cell Movement; Cell Proliferation; Chromones; Drug Synergism; Morpholines; Muscle, Smooth, Vascular; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Rats; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol reversed chronic restraint stress-induced impaired cognitive function in rats.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cognition Disorders; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Hippocampus; Male; Maze Learning; Rats; Rats, Wistar; Resveratrol; Stilbenes; Stress, Physiological | 2017 |
Beneficial effect of resveratrol on phenotypic features and activity of osteoarthritic osteoblasts.
Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Middle Aged; Osteoarthritis; Osteoblasts; Phenotype; Resveratrol; Sirtuin 1; Stilbenes; Treatment Outcome | 2017 |
Resveratrol has anti-thyroid effects both in vitro and in vivo.
Topics: Animals; Antithyroid Agents; Cell Line; Cell Proliferation; Dietary Supplements; Iodide Peroxidase; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Thyroglobulin; Thyroid Gland; Thyroid Hormones | 2017 |
Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Cartilage; Chondrocytes; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intra-Articular; Male; Mice, Inbred C57BL; Osteoarthritis; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
Anti-aging pharmacology in cutaneous wound healing: effects of metformin, resveratrol, and rapamycin by local application.
Topics: Acetyl-CoA Carboxylase; Administration, Cutaneous; Aging; AMP-Activated Protein Kinases; Animals; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Activation; Female; Gene Expression Regulation; Metformin; Mice; Neovascularization, Physiologic; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Resveratrol; Ribosomal Protein S6 Kinases; Sirolimus; Skin; Skin Aging; Stilbenes; Tumor Suppressor Protein p53; Wound Healing; Wounds, Nonpenetrating | 2017 |
Resveratrol suppresses thyroid hormone‑induced osteocalcin synthesis in osteoblasts.
Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Gene Expression Regulation; Mice; Osteoblasts; Osteocalcin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Resveratrol; Stilbenes; Triiodothyronine | 2017 |
Resveratrol Ameliorates Cardiac Dysfunction by Inhibiting Apoptosis via the PI3K/Akt/FoxO3a Pathway in a Rat Model of Diabetic Cardiomyopathy.
Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Forkhead Box Protein O3; Male; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autophagy; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Humans; Inflammasomes; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses.
Topics: Active Transport, Cell Nucleus; Antioxidant Response Elements; Antioxidants; Apigenin; Cell Nucleus; CRISPR-Cas Systems; Gene Expression Regulation; Genes, Reporter; HEK293 Cells; Hep G2 Cells; Humans; Kelch-Like ECH-Associated Protein 1; Luciferases; Mutation; NF-E2-Related Factor 2; Peptide Fragments; Proteasome Endopeptidase Complex; Proteolysis; Recombinant Fusion Proteins; Resveratrol; Small Molecule Libraries; Stilbenes | 2017 |
Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio).
Topics: AMP-Activated Protein Kinase Kinases; Animals; Antioxidants; Caloric Restriction; Caveolin 1; Diet; Eating; Female; Gene Expression Regulation; Lipid Metabolism; Male; Microtubule-Associated Proteins; Phosphorylation; PPAR gamma; Protein Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcription Factors; Triglycerides; Zebrafish; Zebrafish Proteins | 2017 |
Endocytic pathways of optimized resveratrol cubosomes capturing into human hepatoma cells.
Topics: Carcinoma, Hepatocellular; Endocytosis; Hep G2 Cells; Humans; Liquid Crystals; Liver Neoplasms; Nanoparticles; Particle Size; Resveratrol; Solubility; Stilbenes | 2017 |
Resveratrol has dose-dependent effects on DNA fragmentation and mitochondrial activity of ovine secondary follicles cultured in vitro.
Topics: Animals; DNA Fragmentation; Dose-Response Relationship, Drug; Female; Glutathione; Mitochondria; Ovarian Follicle; Oxidative Stress; Resveratrol; Sheep; Stilbenes | 2017 |
Lack of Additive Effects of Resveratrol and Energy Restriction in the Treatment of Hepatic Steatosis in Rats.
Topics: Acetyl-CoA Carboxylase; Alanine Transaminase; AMP-Activated Protein Kinases; Animals; Aspartate Aminotransferases; Caloric Restriction; Coenzyme A Ligases; Diacylglycerol O-Acyltransferase; Diet, High-Fat; Fatty Acid Transport Proteins; Fatty Acids; Fatty Liver; Liver; Male; Organ Size; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Triglycerides; Uncoupling Protein 2 | 2017 |
Regulation of fetuin A gene expression in the neonatal pig liver.
Topics: alpha-2-HS-Glycoprotein; Animals; Antioxidants; Birth Weight; Cytokines; Female; Gene Expression Regulation; Glucagon; Growth Hormone; Hepatocytes; Liver; Male; Resveratrol; RNA, Messenger; Stilbenes; Swine | 2018 |
Resveratrol prevents angiotensin II-induced hypertrophy of vascular smooth muscle cells through the transactivation of growth factor receptors.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Line; CSK Tyrosine-Protein Kinase; Enzyme Activation; Hypertrophy; Male; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Growth Factor; Resveratrol; Signal Transduction; src-Family Kinases; Stilbenes; Transcriptional Activation | 2017 |
Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis.
Topics: Animals; beta Catenin; Chronic Disease; Fibrosis; Male; Prostate; Prostatitis; Proto-Oncogene Proteins c-kit; Rats, Sprague-Dawley; Resveratrol; Stem Cell Factor; Stilbenes; Transforming Growth Factor beta; Urinary Bladder, Overactive; Wnt Proteins | 2017 |
Distinct Mechanisms Underlying Resveratrol-Mediated Protection from Types of Cellular Stress in C6 Glioma Cells.
Topics: Animals; Apoptosis; Caspases; Cell Line, Tumor; Cytoprotection; DNA Damage; Enzyme Activation; Glioma; Models, Biological; Neurofibrillary Tangles; Oxidative Stress; Phosphorylation; Phosphoserine; Rats; Resveratrol; Signal Transduction; Stilbenes; Stress, Physiological; tau Proteins; Ultraviolet Rays | 2017 |
Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application.
Topics: 3T3-L1 Cells; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; CHO Cells; Cricetulus; Enzyme Activation; HEK293 Cells; HeLa Cells; Humans; Mice; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Serine-Threonine Kinases; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2017 |
Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1.
Topics: Animals; Binding Sites; Free Radical Scavengers; Hippocampus; Humans; Mice; Molecular Docking Simulation; Nerve Tissue Proteins; Neurons; Phorbol Esters; Primary Cell Culture; Protein Kinase C-alpha; Resveratrol; SNARE Proteins; Stilbenes; Synaptic Transmission | 2017 |
Upregulation of connexin 43 and apoptosis‑associated protein expression by high glucose in H9c2 cells was improved by resveratrol via the autophagy signaling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Cell Line; Cell Survival; Chloroquine; Connexin 43; Down-Regulation; Glucose; Hyperglycemia; L-Lactate Dehydrogenase; Mice; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Up-Regulation | 2017 |
Dose dependent effect of resveratrol in preventing cisplatin-induced ovarian damage in rats: An experimental study.
Topics: Animals; Antineoplastic Agents; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ovary; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Sirtuin 1 attenuates inflammation and hepatocellular damage in liver transplant ischemia/Reperfusion: From mouse to human.
Topics: Adult; Allografts; Animals; Biopsy; Cells, Cultured; Cytokines; Disease Models, Animal; End Stage Liver Disease; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Kaplan-Meier Estimate; Liver; Liver Transplantation; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Middle Aged; Reperfusion Injury; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Young Adult | 2017 |
Resveratrol ameliorates hypoxia/ischemia-induced brain injury in the neonatal rat via the miR-96/Bax axis.
Topics: Animals; Animals, Newborn; bcl-2-Associated X Protein; Brain; Hypoxia-Ischemia, Brain; MicroRNAs; Neuroprotective Agents; PC12 Cells; Rats; Resveratrol; Stilbenes | 2017 |
A Study of the Therapeutic Effects of Resveratrol on Blunt Chest Trauma-Induced Acute Lung Injury in Rats and the Potential Role of Endocan as a Biomarker of Inflammation.
Topics: Acute Lung Injury; Animals; Antioxidants; Biomarkers; Inflammation; Proteoglycans; Rats; Resveratrol; Stilbenes; Thoracic Injuries; Wounds, Nonpenetrating | 2017 |
Prophylactic supplementation of resveratrol is more effective than its therapeutic use against doxorubicin induced cardiotoxicity.
Topics: Animals; Apoptosis; Biomarkers; Cardiotoxicity; Creatine Kinase, MB Form; Doxorubicin; Drug Administration Schedule; Drug Evaluation, Preclinical; Echocardiography; Heart; Immunohistochemistry; L-Lactate Dehydrogenase; Male; Myocardium; NFATC Transcription Factors; Protective Agents; Random Allocation; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Pharmacological activation of AMPK inhibits incision-evoked mechanical hypersensitivity and the development of hyperalgesic priming in mice.
Topics: AMP-Activated Protein Kinases; Analgesics; Animals; Cells, Cultured; Ganglia, Spinal; Hyperalgesia; Male; Metformin; Mice, Inbred ICR; Neurons; Pain; Pain Threshold; Postoperative Complications; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol efficiently improves pulmonary function via stabilizing mast cells in a rat intestinal injury model.
Topics: Acute Lung Injury; Animals; Antioxidants; Disease Models, Animal; Intestinal Diseases; Male; Mast Cells; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2017 |
Protective role of benzoselenophene derivatives of resveratrol on the induced oxidative stress in intestinal myofibroblasts and osteocytes.
Topics: Cell Line; Cell Survival; Ethylenediamines; Humans; Intestines; Myofibroblasts; Osteocytes; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
The effect of Pro NanoLipospheres (PNL) formulation containing natural absorption enhancers on the oral bioavailability of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in a rat model.
Topics: Administration, Oral; Alkaloids; Animals; Benzodioxoles; Biological Availability; Cannabidiol; Curcumin; Dronabinol; Drug Delivery Systems; Emulsions; Excipients; Gastrointestinal Absorption; Lipids; Male; Nanoparticles; Piperidines; Polyunsaturated Alkamides; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Effect of apigenin, kaempferol and resveratrol on the gene expression and protein secretion of tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) in RAW-264.7 macrophages.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Cell Line; Cytokines; Gene Expression; Inflammation; Interleukin-10; Kaempferols; Lipopolysaccharides; Macrophages; Mice; RAW 264.7 Cells; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
Nicotine Exposure Augments Renal Toxicity of 5-aza-cytidine Through p66shc: Prevention by Resveratrol.
Topics: Antioxidants; Azacitidine; Cell Line; Heme Oxygenase-1; Humans; Kidney Tubules, Proximal; Neoplasms; NF-E2-Related Factor 2; Nicotine; Oxidative Stress; Promoter Regions, Genetic; Resveratrol; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes | 2017 |
Effect of dietary resveratrol supplementation on meat quality, muscle antioxidative capacity and mitochondrial biogenesis of broilers.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Dietary Supplements; Male; Malondialdehyde; Meat; Mitochondria; Muscle, Skeletal; Organelle Biogenesis; Resveratrol; Stilbenes | 2018 |
Resveratrol Protects Against Vacuous Chewing Movements Induced by Chronic Treatment with Fluphenazine.
Topics: Animals; Antioxidants; Antipsychotic Agents; Drug Administration Schedule; Dyskinesias; Fluphenazine; Male; Mastication; Motor Activity; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Delivering Resveratrol on the Buccal Mucosa Using Mucoadhesive Tablets: A Potential Treatment Strategy for Inflammatory Oral Lesions.
Topics: Adhesiveness; Administration, Buccal; Animals; Chemistry, Pharmaceutical; Drug Delivery Systems; Inflammation; Mouth; Mouth Mucosa; Permeability; Resveratrol; Stilbenes; Stomatitis; Swine; Tablets; Viscosity | 2018 |
Pilot scale repeated fed-batch fermentation processes of the wine yeast Dekkera bruxellensis for mass production of resveratrol from Polygonum cuspidatum.
Topics: Dekkera; Fallopia japonica; Fermentation; Resveratrol; Stilbenes; Wine | 2017 |
Novel combination of salinomycin and resveratrol synergistically enhances the anti-proliferative and pro-apoptotic effects on human breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Flow Cytometry; Humans; Inhibitory Concentration 50; MAP Kinase Signaling System; MCF-7 Cells; Pyrans; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Stem Cell Assay | 2017 |
Cryoprotective effect of resveratrol on DNA damage and crucial human sperm messenger RNAs, possibly through 5' AMP-activated protein kinase activation.
Topics: Adult; AMP-Activated Protein Kinases; Cells, Cultured; Cryopreservation; Cryoprotective Agents; DNA Damage; Humans; Male; Resveratrol; RNA, Messenger; Semen Preservation; Sperm Motility; Spermatozoa; Stilbenes; Young Adult | 2018 |
Human skin gene expression: Natural (trans) resveratrol versus five resveratrol analogs for dermal applications.
Topics: Antioxidants; Gene Expression; Gene Expression Profiling; Humans; Organ Culture Techniques; Real-Time Polymerase Chain Reaction; Resveratrol; Skin; Stilbenes | 2017 |
Development and in vitro assessment of psoralen and resveratrol co-loaded ultradeformable liposomes for the treatment of vitiligo.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Liberation; Ficusin; Kinetics; Liposomes; Melanins; Mice; Monophenol Monooxygenase; Particle Size; Resveratrol; Stilbenes; Vitiligo | 2017 |
SIRT1 induces resistance to apoptosis in human granulosa cells by activating the ERK pathway and inhibiting NF-κB signaling with anti-inflammatory functions.
Topics: Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Cells, Cultured; Female; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Gene Knockdown Techniques; Granulosa Cells; Humans; MAP Kinase Signaling System; NF-kappa B; Proline; Resveratrol; Sirtuin 1; Stilbenes; Thiocarbamates | 2017 |
Effects of Resveratrol and ACE Inhibitor Enalapril on Glucose and Lipid Profiles in Mice.
Topics: Adipocytes; Adipogenesis; Adipose Tissue, White; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Diet, High-Fat; Enalapril; Humans; Insulin Resistance; Lipid Metabolism; Lipogenesis; Male; Mice; Resveratrol; Stilbenes | 2017 |
The beneficial effects of resveratrol on steatosis and mitochondrial oxidative stress in HepG2 cells.
Topics: Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; Lipid Metabolism; Mitochondria; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Palmitic Acid; Resveratrol; Stilbenes | 2017 |
Mechanism of isomers and analogues of resveratrol dimers selectively quenching singlet oxygen by UHPLC-ESI-MS
Topics: Benzofurans; Isomerism; Resveratrol; Singlet Oxygen; Stilbenes | 2017 |
Resveratrol: A thermoanalytical study.
Topics: Antioxidants; Calorimetry, Differential Scanning; Resveratrol; Stilbenes; Thermogravimetry | 2017 |
A comparative assessment of antiproliferative properties of resveratrol and ethanol leaf extract of Anogeissus leiocarpus (DC) Guill and Perr against HepG2 hepatocarcinoma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Proliferation; Combretaceae; Flavonoids; Hep G2 Cells; Humans; Liver Neoplasms; Mitochondria; Necrosis; Phenols; Phytotherapy; Plant Extracts; Plant Leaves; Resveratrol; Stilbenes | 2017 |
Resveratrol alleviates diabetic cardiomyopathy in rats by improving mitochondrial function through PGC-1α deacetylation.
Topics: Acetylation; Animals; Antioxidants; Cardiomegaly; Cardiotonic Agents; Cell Line; Diabetic Cardiomyopathies; Male; Mitochondria; Organelle Biogenesis; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Uncoupling Protein 2; Ventricular Function, Left | 2018 |
Treatment with antioxidants ameliorates oxidative damage in a mouse model of propionic acidemia.
Topics: Administration, Oral; Amino Acids, Branched-Chain; Animals; Antioxidants; Disease Models, Animal; Heart; Humans; Lipid Peroxidation; Mice; Organophosphorus Compounds; Oxidative Stress; Propionic Acidemia; Resveratrol; Stilbenes; Ubiquinone | 2017 |
Resveratrol improves high-fat diet induced fatty liver and insulin resistance by concomitantly inhibiting proteolytic cleavage of sterol regulatory element-binding proteins, free fatty acid oxidation, and intestinal triglyceride absorption.
Topics: Animals; Antioxidants; Area Under Curve; Diet, High-Fat; Fatty Acids, Nonesterified; Fatty Liver; Feces; Gene Expression Regulation; Glucose; Glucose Tolerance Test; Insulin Resistance; Intestinal Absorption; Lipase; Liver; Male; Organ Size; Oxidation-Reduction; Oxidative Stress; Proteolysis; Rats, Wistar; Resveratrol; RNA, Messenger; Sterol Regulatory Element Binding Proteins; Stilbenes; Triglycerides | 2018 |
Antitumour activity of resveratrol on human melanoma cells: A possible mechanism related to its interaction with malignant cell telomerase.
Topics: Antineoplastic Agents; Biophysical Phenomena; Cell Line, Tumor; Cell Proliferation; Circular Dichroism; Copper; G-Quadruplexes; Humans; Melanoma; Nucleic Acid Conformation; Resveratrol; Spectrometry, Fluorescence; Spectrum Analysis; Stilbenes; Telomerase | 2017 |
Differentiation of human dental pulp stem cells into neuronal by resveratrol.
Topics: Adult Stem Cells; Cell Differentiation; Cells, Cultured; Dental Pulp; Epithelial Cells; Humans; Neurons; Resveratrol; Stilbenes | 2017 |
Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor Proteins; GATA4 Transcription Factor; Gene Expression Regulation; Isoproterenol; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Resveratrol; Stilbenes | 2017 |
Can resveratrol attenuate testicular damage in neonatal and adult rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin during gestation?
Topics: Age Factors; Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Cytoprotection; Environmental Pollutants; Female; Male; Maternal Exposure; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Resveratrol; Risk Assessment; Semen Analysis; Seminiferous Tubules; Sertoli Cells; Signal Transduction; Spermatogenesis; Stilbenes; Testis | 2018 |
Maternal Resveratrol Treatment Reduces the Risk of Mammary Carcinogenesis in Female Offspring Prenatally Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Hormones; Male; Maternal Exposure; Polychlorinated Dibenzodioxins; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Resveratrol; Stilbenes; Teratogens; Tumor Burden | 2017 |
Identification of Polyphenol-Specific Innate Epitopes That Originated from a Resveratrol Analogue.
Topics: Aging; Animals; Epitopes; Female; Immunoglobulin M; Mice; Mice, Inbred Strains; Molecular Structure; Polyphenols; Resveratrol; Serum Albumin, Bovine; Stilbenes | 2017 |
Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway.
Topics: Animals; Anti-Inflammatory Agents; Doxorubicin; Fibrosis; Glomerulosclerosis, Focal Segmental; Kidney; Male; Mice; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Receptor, Anaphylatoxin C5a; Receptors, G-Protein-Coupled; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Effect of resveratrol on c-fos expression of rat trigeminal spinal nucleus caudalis and C1 dorsal horn neurons following mustard oil-induced acute inflammation.
Topics: Animals; Inflammation; Male; Mustard Plant; Plant Oils; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Resveratrol; Stilbenes; Trigeminal Nucleus, Spinal | 2017 |
Resveratrol increases phagocytosis and lipopolysaccharide-induced interleukin-1β production, but decreases surface expression of Toll-like receptor 2 in THP-1 monocytes.
Topics: Cell Death; Glucuronides; Humans; Interleukin-1beta; Lipopolysaccharides; Monocytes; Phagocytosis; Phytochemicals; Resveratrol; Stilbenes; THP-1 Cells; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2018 |
Resveratrol protects from lipopolysaccharide-induced inflammation in the uterus and prevents experimental preterm birth.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endocannabinoids; Female; Inflammation; Lipopolysaccharides; Mice, Inbred BALB C; Obstetric Labor, Premature; Pregnancy; Prostaglandins; Protective Agents; Resveratrol; Stilbenes; Uterus | 2017 |
4-(E)-{(p-tolylimino)-methylbenzene-1,2-diol} (TIMBD) suppresses HIV1-gp120 mediated production of IL6 and IL8 but not CCL5.
Topics: Active Transport, Cell Nucleus; Astrocytes; Cell Line; Chemokine CCL5; Gene Expression; HIV Envelope Protein gp120; Humans; Interleukin-6; Interleukin-8; Phosphorylation; Resveratrol; STAT3 Transcription Factor; Stilbenes; Transcription Factor RelA; Transfection | 2017 |
The protective effects of Resveratrol against radiation-induced intestinal injury.
Topics: Animals; Antioxidants; Apoptosis; Carbazoles; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Male; Mice, Inbred C57BL; Oxidative Stress; Phytotherapy; Plant Extracts; Radiation Injuries; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2017 |
Attenuation of Multiple Organ Damage by Continuous Low-Dose Solvent-Free Infusions of Resveratrol after Severe Hemorrhagic Shock in Rats.
Topics: Animals; Blood Glucose; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Hemoglobins; Intestine, Small; Isotonic Solutions; Kidney; Lactic Acid; Liver; Lung; Male; Multiple Organ Failure; Peroxidase; Rats; Rats, Wistar; Resuscitation; Resveratrol; Ringer's Lactate; Shock, Hemorrhagic; Sodium Chloride; Stilbenes | 2017 |
Experimental and Theoretical Insights into the Inhibition Mechanism of Prion Fibrillation by Resveratrol and its Derivatives.
Topics: Amyloid; Binding Sites; Models, Chemical; Molecular Docking Simulation; Prion Proteins; Protein Binding; Protein Conformation; Resveratrol; Stilbenes | 2017 |
Resveratrol improves alcoholic fatty liver disease by downregulating HIF-1α expression and mitochondrial ROS production.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Ethanol; Fatty Liver, Alcoholic; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Resveratrol and caloric restriction prevent hepatic steatosis by regulating SIRT1-autophagy pathway and alleviating endoplasmic reticulum stress in high-fat diet-fed rats.
Topics: Animals; Autophagy; Blotting, Western; Body Weight; Caloric Restriction; Diet, High-Fat; Endoplasmic Reticulum Stress; Energy Intake; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Organ Size; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
Effects of dietary supplementation of resveratrol on performance, egg quality, yolk cholesterol and antioxidant enzyme activity of laying hens.
Topics: Animal Feed; Animals; Antioxidants; Chickens; Cholesterol; Diet; Dietary Supplements; Egg Yolk; Female; Ovum; Resveratrol; Stilbenes | 2017 |
Resveratrol induces apoptosis and inhibits adipogenesis by stimulating the SIRT1-AMPKα-FOXO1 signalling pathway in bovine intramuscular adipocytes.
Topics: Adipocytes; AMP-Activated Protein Kinase Kinases; Animals; Apoptosis; Cattle; Forkhead Box Protein O1; Muscle, Skeletal; Protein Kinases; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2018 |
Barley and yeast β-glucans as new emulsifier agents for the development of aqueous natural antifungal formulations.
Topics: beta-Glucans; Botrytis; Drug Compounding; Emulsifying Agents; Fungicides, Industrial; Hordeum; Resveratrol; Stilbenes; Yeasts | 2017 |
Neonatal rat cardiomyocytes as an in vitro model for circadian rhythms in the heart.
Topics: Animals; Animals, Newborn; Apoptosis; Carbazoles; Circadian Clocks; Circadian Rhythm; Doxorubicin; Heart; Models, Biological; Myocytes, Cardiac; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Effects of resveratrol on rat neurosteroid synthetic enzymes.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Alcohol Oxidoreductases; Animals; Chlorocebus aethiops; COS Cells; Membrane Proteins; Molecular Docking Simulation; Neurotransmitter Agents; Oxidoreductases; Rats; Resveratrol; Stilbenes | 2017 |
Quantitative Determination of Anthraquinones and Resveratrol in
Topics: Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Polygonum; Resveratrol; Stilbenes | 2017 |
Resveratrol prevents the combined maternal plus postweaning high-fat-diets-induced hypertension in male offspring.
Topics: Animals; Arginine; Blood Pressure; Diet, High-Fat; Female; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Oxidative Stress; Pregnancy; Rats, Sprague-Dawley; Renin-Angiotensin System; Resveratrol; Stilbenes; Weaning | 2017 |
VDAC1 deacetylation is involved in the protective effects of resveratrol against mitochondria-mediated apoptosis in cardiomyocytes subjected to anoxia/reoxygenation injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carbazoles; Gene Expression Regulation; Humans; Infant, Newborn; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Oxidative Stress; Oxygen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Voltage-Dependent Anion Channel 1 | 2017 |
Comment on Timmers et al. Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care 2016;39:2211-2217.
Topics: Diabetes Mellitus, Type 2; Humans; Resveratrol; Stilbenes; Vitamin D | 2017 |
Response to Comment on Timmers et al. Resveratrol as Add-on Therapy in Subjects With Well-Controlled Type 2 Diabetes: A Randomized Controlled Trial. Diabetes Care 2016;39:2211-2217.
Topics: Diabetes Mellitus, Type 2; Humans; Resveratrol; Stilbenes; Vitamin D | 2017 |
Characteristics of resveratrol and serotonin on antioxidant capacity and susceptibility to oxidation of red blood cells in stored human blood in a time-dependent manner.
Topics: Anticoagulants; Antioxidants; Carbonic Anhydrases; Catalase; Citrates; Erythrocytes; Glucose; Glutathione; Glutathione Peroxidase; Humans; Lipid Peroxidation; Malondialdehyde; Primary Cell Culture; Resveratrol; Serotonin; Stilbenes; Superoxide Dismutase | 2018 |
Cyperaceae Species Are Potential Sources of Natural Mammalian Arginase Inhibitors with Positive Effects on Vascular Function.
Topics: Animals; Arginase; Benzofurans; Cattle; Cyperaceae; Enzyme Inhibitors; Molecular Structure; Rats; Resveratrol; Stilbenes | 2017 |
Resveratrol accumulation and its involvement in stilbene synthetic pathway of Chinese wild grapes during berry development using quantitative proteome analysis.
Topics: Antioxidants; Fruit; Metabolic Networks and Pathways; Plant Proteins; Proteome; Proteomics; Resveratrol; Stilbenes; Tandem Mass Spectrometry; Vitis | 2017 |
Self-Nanoemulsifying Drug Delivery System for Resveratrol: Enhanced Oral Bioavailability and Reduced Physical Fatigue in Rats.
Topics: Administration, Oral; Animals; Biological Availability; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Emulsions; Glycogen; Particle Size; Rats; Resveratrol; Solubility; Stilbenes | 2017 |
Singlet Oxygen Detection Using Red Wine Extracts as Photosensitizers.
Topics: Antioxidants; Gallic Acid; Oxidation-Reduction; Peroxides; Photosensitizing Agents; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Rutin; Singlet Oxygen; Stilbenes; Wine | 2017 |
Resveratrol improves smooth muscle carcinogenesis in the progression of chronic prostatitis via the downregulation of c-kit/SCF by activating Sirt1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogenesis; Chronic Disease; Disease Progression; Down-Regulation; Male; Muscle, Smooth; Prostatitis; Proto-Oncogene Proteins c-kit; Rats; Resveratrol; Sirtuin 1; Stem Cell Factor; Stilbenes; Urinary Bladder | 2017 |
The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway.
Topics: Age Factors; Aging; AMP-Activated Protein Kinases; Animals; Apoptosis; bcl-2-Associated X Protein; Combined Modality Therapy; Disease Models, Animal; Exercise Therapy; Male; Muscle Fibers, Skeletal; Muscle Strength; Muscle, Skeletal; Physical Conditioning, Animal; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley; Resveratrol; Sarcopenia; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Tumor Suppressor Protein p53 | 2017 |
A study of Sirt1 regulation and the effect of resveratrol on synoviocyte invasion and associated joint destruction in rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Models, Animal; Gene Expression; Joints; Matrix Metalloproteinases; Rats; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Synoviocytes | 2017 |
Identification of Resveratrol, an Herbal Compound, as an Activator of the Calcium-Activated Chloride Channel, TMEM16A.
Topics: Animals; Anoctamin-1; Calcium Signaling; Chloride Channel Agonists; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gastrointestinal Motility; Guinea Pigs; HEK293 Cells; Humans; Ileum; Neoplasm Proteins; Plants, Medicinal; Resveratrol; Stilbenes | 2017 |
The protein restriction mimetic Resveratrol is an autophagy inducer stronger than amino acid starvation in ovarian cancer cells.
Topics: Amino Acids; Antineoplastic Agents, Phytogenic; Autophagy; Blotting, Western; Cell Line, Tumor; Cluster Analysis; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Fluorescence; Ovarian Neoplasms; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Suppression of Oxidative Stress and Apoptosis in Electrically Stimulated Neonatal Rat Cardiomyocytes by Resveratrol and Underlying Mechanisms.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electric Stimulation; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2017 |
Effect of Resveratrol on Critical-Sized Calvarial Defects of Diabetic Rats: Histometric and Gene Expression Analysis.
Topics: Animals; Biomarkers; Bone Density Conservation Agents; Bone Regeneration; Diabetes Mellitus, Experimental; Gene Expression Regulation; Insulin; Male; Rats; Rats, Wistar; Resveratrol; Skull; Stilbenes; Streptozocin; Wound Healing | 2017 |
Resveratrol promotes human embryonic stem cells self-renewal by targeting SIRT1-ERK signaling pathway.
Topics: Benzamides; Carbazoles; Cell Differentiation; Cell Proliferation; Cell Self Renewal; Diphenylamine; Gene Expression Regulation, Developmental; Human Embryonic Stem Cells; Humans; MAP Kinase Signaling System; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
[Apoptosis mechanism of taxol combined with resveratrol on human laryngeal carcinoma Hep-2 cells].
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Cell Line, Tumor; Humans; Laryngeal Neoplasms; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2016 |
Lipophilization of Resveratrol and Effects on Antioxidant Activities.
Topics: Antioxidants; Chromatography, High Pressure Liquid; Esterification; Fatty Acids; Free Radical Scavengers; Mass Spectrometry; Resveratrol; Stilbenes; Structure-Activity Relationship | 2017 |
Proliferative endocrine effects of adipose tissue from obese animals on MCF7 cells are ameliorated by resveratrol supplementation.
Topics: Adipocytes; Adipokines; Adipose Tissue; Animals; Body Weight; Breast Neoplasms; Cell Cycle; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Endocrine System; Female; Humans; Male; MCF-7 Cells; Obesity; Rats; Rats, Zucker; Resveratrol; Stilbenes; Time Factors | 2017 |
SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice.
Topics: Animals; Cell Line; Diabetic Cardiomyopathies; DNA-Binding Proteins; ERRalpha Estrogen-Related Receptor; Humans; Mice; Mice, Knockout; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; NF-E2-Related Factor 1; Receptors, Estrogen; Resveratrol; Sirtuin 1; Stilbenes; Transcription Factors | 2017 |
Resveratrol-loaded nanoparticles conjugated with kidney injury molecule-1 as a drug delivery system for potential use in chronic kidney disease.
Topics: Animals; Antibodies; Autophagy; Cell Line; Cell Survival; Creatinine; Drug Carriers; Drug Liberation; Epithelial Cells; Hepatitis A Virus Cellular Receptor 1; Humans; Inflammasomes; Interleukin-1beta; Kidney Tubules; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Nephritis, Interstitial; NLR Family, Pyrin Domain-Containing 3 Protein; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Renal Insufficiency, Chronic; Resveratrol; Stilbenes | 2017 |
Resveratrol protects against mitochondrial dysfunction through autophagy activation in human nucleus pulposus cells.
Topics: Animals; Antioxidants; Cells, Cultured; Dose-Response Relationship, Drug; Female; Humans; Intervertebral Disc Degeneration; Male; Mitochondria; Nucleus Pulposus; Rabbits; Resveratrol; Stilbenes; Treatment Outcome | 2017 |
Resveratrol, piceatannol and analogs inhibit activation of both wild-type and T877A mutant androgen receptor.
Topics: Androgen Receptor Antagonists; Cell Line, Tumor; Cell Survival; Humans; Kallikreins; Prostate-Specific Antigen; Receptors, Androgen; Resveratrol; Stilbenes | 2017 |
Metabolites of flavonoid compounds preserve indices of endothelial cell nitric oxide bioavailability under glucotoxic conditions.
Topics: Antioxidants; Aorta; Biological Availability; Diabetes Mellitus; Diet; Endothelial Cells; Endothelium, Vascular; Flavonoids; Glucose; Humans; Insulin; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Proanthocyanidins; Proto-Oncogene Proteins c-akt; Quercetin; Resveratrol; Stilbenes | 2017 |
Hepatic transcriptome analysis of juvenile GIFT tilapia (Oreochromis niloticus), fed diets supplemented with different concentrations of resveratrol.
Topics: Animals; China; Cichlids; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Immunity, Innate; Liver; Resveratrol; Stilbenes; Transcriptome | 2018 |
The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Gene Expression Regulation; Inflammation; Interleukin-6; Interleukin-8; Lipopolysaccharides; Lung; Malondialdehyde; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Pulmonary Disease, Chronic Obstructive; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2017 |
Resveratrol-Enriched Rice Attenuates UVB-ROS-Induced Skin Aging via Downregulation of Inflammatory Cascades.
Topics: Down-Regulation; Humans; Inflammation; Oryza; Reactive Oxygen Species; Resveratrol; Skin Aging; Stilbenes; Ultraviolet Rays | 2017 |
Inhibitory effects of 17β-estradiol or a resveratrol dimer on hypoxia-inducible factor-1α in genioglossus myoblasts: Involvement of ERα and its downstream p38 MAPK pathways.
Topics: Animals; Cell Hypoxia; Estradiol; Estrogen Receptor alpha; Gene Knockdown Techniques; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Myoblasts; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes | 2017 |
SIRT1 confers protection against ischemia/reperfusion injury in cardiomyocytes via regulation of uncoupling protein 2 expression.
Topics: Animals; Cell Hypoxia; Cell Line; Cell Survival; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Myocytes, Cardiac; Rats; Resveratrol; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Stilbenes; Uncoupling Protein 2 | 2017 |
Resveratrol suppresses P-selectin, PSGL-1, and VWF through SIRT1 signaling pathway.
Topics: Antioxidants; Carbazoles; Cells, Cultured; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Membrane Glycoproteins; Oxidants; P-Selectin; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; von Willebrand Factor | 2017 |
Biological effects of combined resveratrol and vitamin D3 on ovarian tissue.
Topics: Animals; Antioxidants; Biological Availability; Cell Survival; CHO Cells; Cholecalciferol; Cricetulus; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Female; Ovary; Proto-Oncogene Proteins c-akt; Rats, Wistar; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Tissue Distribution | 2017 |
Preparation and biological activity studies of resveratrol loaded ionically cross-linked chitosan-TPP nanoparticles.
Topics: Cell Line, Tumor; Chitosan; Drug Carriers; Humans; Nanoparticles; Resveratrol; Stilbenes | 2017 |
Resveratrol inhibits proliferation, promotes differentiation and melanogenesis in HT-144 melanoma cells through inhibition of MEK/ERK kinase pathway.
Topics: Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Humans; MAP Kinase Signaling System; Melanins; Melanoma; Mitogen-Activated Protein Kinase 3; Resveratrol; Stilbenes | 2017 |
Silver nanoparticles enhance the apoptotic potential of gemcitabine in human ovarian cancer cells: combination therapy for effective cancer treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Delivery Systems; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Metal Nanoparticles; Ovarian Neoplasms; Resveratrol; Silver; Stilbenes | 2017 |
Resveratrol attenuates high glucose-induced endothelial cell apoptosis via mediation of store-operated calcium entry.
Topics: Apoptosis; Calcium; Calcium Signaling; Cell Line; Endothelial Cells; Glucose; Humans; Resveratrol; Stilbenes | 2018 |
Effects of Hypobaric Hypoxia on Rat Retina and Protective Response of Resveratrol to the Stress.
Topics: Altitude Sickness; Animals; Antioxidants; Apoptosis; Cytokines; Disease Models, Animal; Humans; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Retina; Retinal Diseases; Stilbenes; Thioredoxins | 2017 |
Impact of resveratrol on bone repair in rats exposed to cigarette smoke inhalation: histomorphometric and bone-related gene expression analysis.
Topics: Animals; Gene Expression; Male; Polymerase Chain Reaction; Rats; Rats, Wistar; Resveratrol; Skull; Smoking; Stilbenes; Wound Healing | 2018 |
Resveratrol suppresses melanoma by inhibiting NF-κB/miR-221 and inducing TFG expression.
Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinogenesis; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Mice; Mice, SCID; MicroRNAs; Proteins; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2017 |
A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.
Topics: Cell Proliferation; Colorectal Neoplasms; Humans; MCF-7 Cells; Mutation; Proto-Oncogene Proteins p21(ras); Resveratrol; Signal Transduction; Stilbenes | 2018 |
Dual Effects of Resveratrol on Cell Death and Proliferation of Colon Cancer Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Death; Cell Proliferation; Colonic Neoplasms; DNA Damage; Dose-Response Relationship, Drug; HCT116 Cells; HT29 Cells; Humans; L-Lactate Dehydrogenase; Quercetin; Reactive Oxygen Species; Resveratrol; Sirtuins; Stilbenes; Superoxides | 2017 |
Resveratrol suppresses the alveolar bone resorption induced by artificial trauma from occlusion in mice.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Dental Occlusion, Traumatic; Gene Expression; Gingiva; Macrophages; Male; Mice; Osteogenesis; Periodontal Ligament; RAW 264.7 Cells; Resveratrol; RNA; Stilbenes | 2018 |
Mechanical stress rapidly induces E-resveratrol and E-piceatannol biosynthesis in grape canes stored as a freshly-pruned byproduct.
Topics: Resveratrol; Stilbenes; Stress, Mechanical; Vitis | 2018 |
Chemical composition, bioactive compounds, and volatiles of six table grape varieties (Vitis vinifera L.).
Topics: Anthocyanins; Fruit; Oman; Resveratrol; Stilbenes; Vitis | 2018 |
Resveratrol ameliorated the behavioral deficits in a mouse model of post-traumatic stress disorder.
Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Immobilization; Male; Maze Learning; Mice; Mice, Inbred ICR; Resveratrol; Stilbenes; Stress Disorders, Post-Traumatic | 2017 |
Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway.
Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Humans; Lymphoma, Extranodal NK-T-Cell; Mitochondria; Resveratrol; Stilbenes | 2017 |
EcoSynther: A Customized Platform To Explore the Biosynthetic Potential in E. coli.
Topics: Algorithms; Biosynthetic Pathways; Carotenoids; Escherichia coli; Lycopene; Metabolic Engineering; Metabolomics; Resveratrol; Stilbenes | 2017 |
Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion Molecules; Cell Movement; Colorectal Neoplasms; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesions; HCT116 Cells; Humans; Integrin beta1; Neoplasm Invasiveness; NF-kappa B; Protein Kinase Inhibitors; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Tumor Microenvironment | 2017 |
Potential miRNA involvement in the anti-adipogenic effect of resveratrol and its metabolites.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; Dose-Response Relationship, Drug; Mice; MicroRNAs; Resveratrol; Stilbenes; Transcription Factors | 2017 |
Production of drug nanosuspensions: effect of drug physical properties on nanosizing efficiency.
Topics: Calorimetry, Differential Scanning; Crystallization; Desiccation; Glyburide; Hesperidin; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Powder Diffraction; Quercetin; Resveratrol; Rutin; Stilbenes; Technology, Pharmaceutical | 2018 |
Resveratrol Enhances Neurite Outgrowth and Synaptogenesis Via Sonic Hedgehog Signaling Following Oxygen-Glucose Deprivation/Reoxygenation Injury.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Female; Glucose; Hedgehog Proteins; Neurogenesis; Neuronal Outgrowth; Neurons; Neuroprotective Agents; Oxygen; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol and cognitive performance.
Topics: Cognition; Humans; Memory; Resveratrol; Stilbenes | 2018 |
Upregulation of FcγRIIB by resveratrol via NF-κB activation reduces B-cell numbers and ameliorates lupus.
Topics: Animals; Anti-Inflammatory Agents; Autoantibodies; B-Lymphocytes; Cell Membrane; Disease Models, Animal; Gene Expression Regulation; Lupus Erythematosus, Systemic; Lupus Nephritis; Mice; Mice, Inbred MRL lpr; Models, Biological; Myeloid Cells; NF-kappa B; Promoter Regions, Genetic; Receptors, IgG; Resveratrol; Splenomegaly; Stilbenes; Survival Rate; Transcriptional Activation | 2017 |
Antioxidant activities of novel resveratrol analogs in breast cancer.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Anticarcinogenic Agents; Antioxidants; Breast; Breast Neoplasms; Catechols; Cell Line; Cell Proliferation; Cell Survival; Deoxyguanosine; Dietary Supplements; DNA Damage; Enzyme Induction; Estradiol; Female; Humans; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Reactive Oxygen Species; Resveratrol; Schiff Bases; Signal Transduction; Stilbenes; Superoxide Dismutase | 2018 |
Protective effects of resveratrol on mitochondrial function in the hippocampus improves inflammation-induced depressive-like behavior.
Topics: Animals; Antidepressive Agents; Antioxidants; Apoptosis; Cyclic N-Oxides; Depression; Disease Models, Animal; Food Preferences; Hippocampus; Inflammation; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred ICR; Mitochondria; Resveratrol; Rotenone; Stilbenes; Swimming; Uncoupling Agents | 2017 |
Resveratrol and cognitive performance: Selecting the evidence.
Topics: Cognition; Humans; Memory; Resveratrol; Stilbenes | 2018 |
Resveratrol Inhibits the Epidermal Growth Factor-Induced Migration of Osteoblasts: the Suppression of SAPK/JNK and Akt.
Topics: Animals; Anthracenes; Cell Movement; Cells, Cultured; Epidermal Growth Factor; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; rho-Associated Kinases; Sirtuin 1; Stilbenes | 2017 |
Resveratrol, pterostilbene, and baicalein: plant-derived anti-biofilm agents.
Topics: Anti-Infective Agents; Biofilms; Candida albicans; Escherichia coli; Flavanones; Microbial Sensitivity Tests; Plant Extracts; Pseudomonas aeruginosa; Resveratrol; Staphylococcus epidermidis; Stilbenes | 2018 |
Coupled transcript and metabolite identification: insights on induction and synthesis of resveratrol in peanut, wild relatives and synthetic allotetraploid.
Topics: Arachis; Genotype; Plant Leaves; Plant Proteins; Resveratrol; RNA, Messenger; Stilbenes; Tetraploidy; Transcriptional Activation; Ultraviolet Rays | 2017 |
Resveratrol enhances anticancer effects of paclitaxel in HepG2 human liver cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Paclitaxel; Resveratrol; RNA, Messenger; Stilbenes | 2017 |
Protective effects of the resveratrol analog piceid in dopaminergic SH-SY5Y cells.
Topics: Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Dopamine; Dopaminergic Neurons; Extracellular Signal-Regulated MAP Kinases; Glucosides; Humans; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes | 2018 |
Receptor-Mediated Attachment and Uptake of Hyaluronan Conjugates by Breast Cancer Cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Delivery Systems; HeLa Cells; Humans; Hyaluronan Receptors; Hyaluronic Acid; Nanomedicine; Resveratrol; Stilbenes | 2017 |
Resveratrol inhibits proliferation and migration through SIRT1 mediated post‑translational modification of PI3K/AKT signaling in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol Ameliorates Retinal Ischemia/Reperfusion Injury in C57BL/6J Mice via Downregulation of Caspase-3.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Disease Models, Animal; Down-Regulation; Gene Expression Regulation, Enzymologic; In Situ Nick-End Labeling; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Resveratrol; Retinal Degeneration; RNA, Messenger; Stilbenes | 2017 |
In vitro and in vivo evaluation of targeting tumor with folate-based amphiphilic multifunctional stabilizer for resveratrol nanosuspensions.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Drug Delivery Systems; Drug Stability; Folic Acid; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron; Nanoparticles; Phosphatidylethanolamines; Polyethylene Glycols; Resveratrol; Stilbenes; Suspensions; Xenograft Model Antitumor Assays | 2017 |
Assessment of a nutritional supplement containing resveratrol, prebiotic fiber, and omega-3 fatty acids for the prevention and treatment of mild traumatic brain injury in rats.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries, Traumatic; Dietary Supplements; Disease Models, Animal; Exploratory Behavior; Fatty Acids, Omega-3; Female; Gene Expression Regulation; Male; Maze Learning; Memory, Short-Term; Neurofibromatosis 1; Prebiotics; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Swimming | 2017 |
Deciphering molecular mechanisms of arginine deiminase-based therapy - Comparative response analysis in paired human primary and recurrent glioblastomas.
Topics: Autophagy; Bacterial Proteins; Cell Line, Tumor; Cell Survival; Cellular Senescence; Curcumin; Gamma Rays; Glioblastoma; Heat-Shock Proteins; Humans; Hydrolases; Quinacrine; Recombinant Proteins; Resveratrol; Stilbenes; Streptococcus pyogenes; Superoxide Dismutase; Up-Regulation | 2017 |
Neuronal SIRT1 (Silent Information Regulator 2 Homologue 1) Regulates Glycolysis and Mediates Resveratrol-Induced Ischemic Tolerance.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Glycolysis; Mice; Mice, Knockout; Neurons; Neuroprotective Agents; Resveratrol; Sirtuin 1; Stilbenes; Stroke | 2017 |
Aggregation of Aβ(17-36) in the Presence of Naturally Occurring Phenolic Inhibitors Using Coarse-Grained Simulations.
Topics: Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzaldehydes; Catechin; Curcumin; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Aggregates; Resveratrol; Stilbenes | 2017 |
Resveratrol improved detrusor fibrosis induced by mast cells during progression of chronic prostatitis in rats.
Topics: Animals; Chronic Disease; Collagen; Down-Regulation; Fibrosis; Male; Mast Cells; Muscle, Smooth; Prostatitis; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta; Urinary Bladder; Urinary Bladder, Overactive; Wnt Signaling Pathway | 2017 |
Special Issue: Improvements for Resveratrol Efficacy.
Topics: Cyclodextrins; Humans; Liposomes; Resveratrol; Stilbenes | 2017 |
Resveratrol Suppresses Growth and Migration of Myelodysplastic Cells by Inhibiting the Expression of Elevated Cyclin D1 (CCND1).
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Case-Control Studies; Cell Cycle; Cell Movement; Cell Proliferation; Cyclin D1; Gene Expression Regulation; Humans; Myelodysplastic Syndromes; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2017 |
Resveratrol Ameliorates Contrast Induced Nephropathy Through the Activation of SIRT1-PGC-1α-Foxo1 Signaling in Mice.
Topics: Animals; Apoptosis; Contrast Media; Forkhead Box Protein O1; Kidney Diseases; Mice; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2017 |
Resveratrol attenuates bone cancer pain through regulating the expression levels of ASIC3 and activating cell autophagy.
Topics: Acid Sensing Ion Channels; AMP-Activated Protein Kinases; Animals; Autophagy; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Female; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2017 |
The role of resveratrol on full - Thickness uterine wound healing in rats.
Topics: Animals; Antioxidants; Female; Glutathione Peroxidase; Malondialdehyde; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase; Treatment Outcome; Uterus; Vascular Endothelial Growth Factor A; Wound Healing | 2017 |
SIRT1 activation by resveratrol reduces brain edema and neuronal apoptosis in an experimental rat subarachnoid hemorrhage model.
Topics: Animals; Apoptosis; Brain Edema; Caspase 3; Disease Models, Animal; Fluorescent Antibody Technique; Male; Mortality; Neurons; Neuroprotection; Occludin; Rats; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Subarachnoid Hemorrhage; Zonula Occludens-1 Protein | 2017 |
Apurinic/apyrimidinic endonuclease 1 (APE1) contributes to resveratrol‑induced neuroprotection against oxygen‑glucose deprivation and re‑oxygenation injury in HT22 cells: Involvement in reducing oxidative DNA damage.
Topics: Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Gene Knockdown Techniques; Glucose; Humans; Neuroprotection; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Stilbenes | 2017 |
Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence.
Topics: Alternative Splicing; Cell Cycle; Cell Proliferation; Cells, Cultured; Cellular Senescence; Fibroblasts; Humans; Resveratrol; RNA Splicing Factors; Small Molecule Libraries; Stilbenes | 2017 |
Resveratrol stimulates the metabolic reprogramming of human CD4
Topics: Adult; Antioxidants; Ataxia Telangiectasia Mutated Proteins; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; DNA Damage; G1 Phase Cell Cycle Checkpoints; Gene Expression Profiling; Glycolysis; Humans; Oxidative Phosphorylation; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Isoflavones Induce BEX2-Dependent Autophagy to Prevent ATR-Induced Neurotoxicity in SH-SY5Y Cells.
Topics: Apoptosis; Atrazine; Autophagy; Blotting, Western; Cell Line, Tumor; Cell Survival; Curcumin; Flow Cytometry; Humans; Isoflavones; Nerve Tissue Proteins; Polyphenols; Quercetin; Real-Time Polymerase Chain Reaction; Resveratrol; Sincalide; Stilbenes; TOR Serine-Threonine Kinases; Tyrosine 3-Monooxygenase | 2017 |
The effect of leptin and resveratrol on JAK/STAT pathways and Sirt-1 gene expression in the renal tissue of ischemia/reperfusion induced rats.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Gene Expression; Kidney; Leptin; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor; Reperfusion Injury; Resveratrol; RNA, Messenger; Signal Transduction; Sirtuin 1; STAT1 Transcription Factor; STAT3 Transcription Factor; Stilbenes; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol alleviates heat stress-induced impairment of intestinal morphology, microflora, and barrier integrity in broilers.
Topics: Animals; Avian Proteins; Chickens; Gastrointestinal Microbiome; Heat Stress Disorders; Intestines; Male; Protective Agents; Random Allocation; Resveratrol; RNA, Messenger; Stilbenes; Tight Junction Proteins | 2017 |
Dietary resveratrol increases mid-life fecundity of female Nothobranchius guentheri.
Topics: Age Factors; Animal Feed; Animals; Antioxidants; Body Weight; Diet; Female; Fertility; Fish Proteins; Fishes; Nicotinamide Phosphoribosyltransferase; Ovary; Resveratrol; Sexual Maturation; Sirtuin 1; Stilbenes | 2018 |
Suppression of Sirtuin-1 Increases IL-6 Expression by Activation of the Akt Pathway During Allergic Asthma.
Topics: Animals; Asthma; Blotting, Western; Cell Line; Chromones; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Humans; Immunohistochemistry; Interleukin-6; Lung; Morpholines; Naphthols; Phenylpropionates; Proto-Oncogene Proteins c-akt; Resveratrol; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes | 2017 |
Switching enzyme specificity from phosphate to resveratrol glucosylation.
Topics: Enzyme-Linked Immunosorbent Assay; Glucosyltransferases; Glycosylation; Models, Molecular; Molecular Structure; Phosphates; Resveratrol; Stilbenes; Substrate Specificity | 2017 |
Prolonged exposure of resveratrol induces reactive superoxide species-independent apoptosis in murine prostate cells.
Topics: Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Male; Membrane Potential, Mitochondrial; Mice; Prostatic Neoplasms; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Trans-resveratrol-loaded nonionic lamellar liquid-crystalline systems: structural, rheological, mechanical, textural, and bioadhesive characterization and evaluation of in vivo anti-inflammatory activity.
Topics: Adhesiveness; Adhesives; Animals; Anti-Inflammatory Agents; Humans; Ions; Liquid Crystals; Male; Materials Testing; Mechanical Phenomena; Mice; Resveratrol; Rheology; Scattering, Small Angle; Skin; Solubility; Stilbenes; Sus scrofa; X-Ray Diffraction | 2017 |
Resveratrol improves urinary dysfunction in rats with chronic prostatitis and suppresses the activity of the stem cell factor/c-Kit signaling pathway.
Topics: Animals; Chronic Disease; Diphtheria-Tetanus-Pertussis Vaccine; Disease Models, Animal; Down-Regulation; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostate; Prostatitis; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Solifenacin Succinate; Stem Cell Factor; Stilbenes; Urinary Bladder | 2017 |
Anticancer Effects of Resveratrol-Loaded Solid Lipid Nanoparticles on Human Breast Cancer Cells.
Topics: Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D1; Female; Gene Expression Regulation, Neoplastic; Humans; Lipids; Nanoparticles; Particle Size; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Resveratrol; Stilbenes | 2017 |
Resveratrol-based cinnamic ester hybrids: synthesis, characterization, and anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Cinnamates; Crystallography, X-Ray; Esters; Macrophages; Mice; Molecular Docking Simulation; Molecular Structure; NF-kappa B p50 Subunit; RAW 264.7 Cells; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol controlled the fate of porcine pancreatic stem cells through the Wnt/β-catenin signaling pathway mediated by Sirt1.
Topics: Animals; Cell Lineage; Cell Proliferation; Cells, Cultured; Glucose; Pancreas; Resveratrol; Sirtuin 1; Stem Cells; Stilbenes; Swine; Wnt Signaling Pathway | 2017 |
Resveratrol increases nucleus pulposus matrix synthesis through activating the PI3K/Akt signaling pathway under mechanical compression in a disc organ culture.
Topics: Aggrecans; Animals; Collagen; Culture Media; Dose-Response Relationship, Drug; Glycosaminoglycans; Humans; Hydroxyproline; Intervertebral Disc; Male; Nucleus Pulposus; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Regeneration; Resveratrol; Stilbenes; Stress, Mechanical; Swine | 2017 |
Dietary Compound Resveratrol Is a Pan-BET Bromodomain Inhibitor.
Topics: Acetylation; Antineoplastic Agents, Phytogenic; Cell Cycle Proteins; Diet; Epigenesis, Genetic; Gene Expression; Histones; Humans; Kinetics; Lysine; Molecular Docking Simulation; Neoplasms; Nuclear Proteins; Phytotherapy; Plant Extracts; Proteins; Resveratrol; Stilbenes; Transcription Factors | 2017 |
Involvement of Resveratrol and ω-3 Polyunsaturated Fatty Acids on Sirtuin 1 Gene Expression in THP1 Cells.
Topics: Cell Line, Tumor; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Gene Expression Regulation, Enzymologic; Glucose; Humans; Mannitol; Monocytes; Resveratrol; Sirtuin 1; Stilbenes | 2017 |
The Neuroprotective Effects of SIRT1 on NMDA-Induced Excitotoxicity.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cerebral Cortex; Excitatory Postsynaptic Potentials; Humans; N-Methylaspartate; Rats; Rats, Wistar; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transfection | 2017 |
[Effect of resveratrol in regulating proliferation and apoptosis of rectal cancer cells via up-regulating PTEN].
Topics: Apoptosis; Caco-2 Cells; Caspase 3; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rectal Neoplasms; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2017 |
Shell-crosslinked zein nanocapsules for oral codelivery of exemestane and resveratrol in breast cancer therapy.
Topics: Administration, Oral; Androstadienes; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cross-Linking Reagents; Drug Combinations; Drug Liberation; Female; Glutaral; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Male; Mice; Nanocapsules; Particle Size; Rats, Wistar; Resveratrol; Solubility; Stilbenes; Surface Properties; Tissue Distribution; Zein | 2017 |
In Vitro Dissolution, Cellular Membrane Permeability, and Anti-Inflammatory Response of Resveratrol-Encapsulated Mesoporous Silica Nanoparticles.
Topics: Animals; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; Drug Liberation; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Nanocapsules; Porosity; RAW 264.7 Cells; Resveratrol; Silicon Dioxide; Solubility; Stilbenes; Surface Properties | 2017 |
Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.
Topics: Apoptosis; Cartilage, Articular; Cells, Cultured; Chondrocytes; Down-Regulation; Gene Knockdown Techniques; Humans; Inflammation; Lymphotoxin-alpha; NF-kappa B; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Up-Regulation | 2017 |
Influence of resveratrol pretreatment on thawed bovine embryo quality and mitochondrial DNA copy number.
Topics: Animals; Cattle; Cryopreservation; DNA Copy Number Variations; DNA, Mitochondrial; Embryo Culture Techniques; Embryo Transfer; Female; Gene Expression Regulation, Developmental; Pregnancy; Pregnancy Rate; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation | 2018 |
Topics: Animals; beta-Naphthoflavone; Cell Culture Techniques; Cytochrome P-450 CYP1A1; Male; Mice; Mice, Knockout; Mitochondria; Resveratrol; Stilbenes | 2017 |
Resveratrol suppresses ethanol stress in winery and bottom brewery yeast by affecting superoxide dismutase, lipid peroxidation and fatty acid profile.
Topics: Antioxidants; Ethanol; Fatty Acids; Lipid Metabolism; Lipid Peroxidation; Lipids; Resveratrol; Saccharomyces cerevisiae; Stilbenes; Stress, Physiological; Superoxide Dismutase; Wine | 2017 |
Ameliorative potential of sitagliptin and/or resveratrol on experimentally-induced clear cell renal cell carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Carcinoma, Renal Cell; Immunohistochemistry; Kidney Function Tests; Kidney Neoplasms; Male; Neoplasms, Experimental; Rats; Rats, Wistar; Resveratrol; Sitagliptin Phosphate; Stilbenes | 2018 |
Resveratrol promotes hUC-MSCs engraftment and neural repair in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cell Differentiation; Disease Models, Animal; Hippocampus; Humans; Memory; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Transgenic; Neurogenesis; Neurons; Resveratrol; Stilbenes; Umbilical Cord | 2018 |
Octenylsuccinate hydroxypropyl phytoglycogen, a dendrimer-like biopolymer, solubilizes poorly water-soluble active pharmaceutical ingredients.
Topics: Celecoxib; Dendrimers; Docetaxel; Fenofibrate; Glycogen; Griseofulvin; Pharmaceutic Aids; Resveratrol; Solubility; Solvents; Stilbenes; Succinates; Surface-Active Agents; Taxoids | 2018 |
The inhibition of indoleamine 2, 3-dioxygenase 1 by connexin 43.
Topics: Animals; Cell Line, Tumor; Connexin 43; Gene Knockdown Techniques; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Neoplasms; Resveratrol; RNA Interference; RNA, Small Interfering; Salmonella enterica; Signal Transduction; Stilbenes; T-Lymphocytes; Up-Regulation | 2017 |
Resveratrol enhancement staphylococcus aureus survival under levofloxacin and photodynamic treatments.
Topics: Anti-Bacterial Agents; Antioxidants; Hydrogen Peroxide; Levofloxacin; Methylene Blue; Microbial Sensitivity Tests; Oxidants; Photochemotherapy; Resveratrol; Staphylococcus aureus; Stilbenes; Superoxides | 2018 |
Resveratrol analogues like piceatannol are potent antioxidants as quantitatively demonstrated through the high scavenging ability against reactive oxygen species and methyl radical.
Topics: Antioxidants; Dose-Response Relationship, Drug; Humans; Methane; Molecular Structure; Reactive Oxygen Species; Resveratrol; Stilbenes; Structure-Activity Relationship | 2017 |
Resveratrol prevents osteoporosis by upregulating FoxO1 transcriptional activity.
Topics: Animals; Cell Differentiation; Disease Models, Animal; Female; Forkhead Box Protein O1; Gene Expression Regulation; Humans; Hydrogen Peroxide; Mice; Osteoclasts; Osteoporosis; Osteoprotegerin; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RANK Ligand; RAW 264.7 Cells; Resveratrol; Signal Transduction; Stilbenes | 2018 |
High glucose upregulates endothelin type B receptors in vascular smooth muscle cells via the downregulation of Sirt1.
Topics: Animals; Gene Expression Regulation; Glucose; MAP Kinase Signaling System; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Organ Culture Techniques; Rats; Receptor, Endothelin B; Resveratrol; Sirtuin 1; Stilbenes; Vasoconstriction; Viper Venoms | 2018 |
Resveratrol-mediated apoptosis in renal cell carcinoma via the p53/AMP‑activated protein kinase/mammalian target of rapamycin autophagy signaling pathway.
Topics: AMP-Activated Protein Kinases; Autophagy; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression; Humans; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Tumor Suppressor Protein p53 | 2018 |
Anti-inflammatory activity of resveratrol prevents inflammation by inhibiting NF‑κB in animal models of acute pharyngitis.
Topics: Animals; Anti-Inflammatory Agents; Chemokine CXCL2; Cyclooxygenase 2; Drug Evaluation, Preclinical; Interleukin-6; Male; NF-kappa B; Pharyngitis; Pharynx; Rabbits; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2018 |
Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression.
Topics: Animals; Biomarkers; Chronic Disease; Disease Models, Animal; Fibrosis; Humans; Male; Mast Cells; Prostatic Diseases; Prostatitis; Resveratrol; Stilbenes; Transforming Growth Factor beta; Tryptases; Urologic Diseases; Wnt Signaling Pathway | 2018 |
Cytotoxicity of Labruscol, a New Resveratrol Dimer Produced by Grapevine Cell Suspensions, on Human Skin Melanoma Cancer Cell Line HT-144.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bioreactors; Cell Line, Tumor; Cell Survival; Dimerization; Humans; Magnetic Resonance Spectroscopy; Melanoma; Melanoma, Cutaneous Malignant; Molecular Structure; Plant Cells; Resveratrol; Skin Neoplasms; Stilbenes; Vitis | 2017 |
Effects of a Grapevine Shoot Extract Containing Resveratrol and Resveratrol Oligomers on Intestinal Adenoma Development in Mice: In Vitro and In Vivo Studies.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Caspases; Cell Proliferation; Female; Intestinal Neoplasms; Male; Mice, Mutant Strains; Phenols; Resveratrol; Stilbenes | 2018 |
Resveratrol Exerts Antioxidant Effects by Activating SIRT2 To Deacetylate Prx1.
Topics: Antioxidants; Gene Expression Regulation; Hep G2 Cells; Homeodomain Proteins; Humans; Hydrogen Peroxide; Resveratrol; Sirtuin 2; Stilbenes | 2017 |
Resveratrol pretreatment enhanced homing of SDF-1α-preconditioned bone marrow-derived mesenchymal stem cells in a rat model of liver cirrhosis.
Topics: Animals; Bone Marrow Cells; Chemokine CXCL12; Disease Models, Animal; Graft Enhancement, Immunologic; Liver Cirrhosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2018 |
The Effects of 4'-Esterified Resveratrol Derivatives on Calcium Dynamics in Breast Cancer Cells.
Topics: Antineoplastic Agents; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Cell Survival; Esters; Female; Humans; Molecular Structure; Receptors, Estrogen; Resveratrol; Stilbenes | 2017 |
Beneficial effect of resveratrol on α‑naphthyl isothiocyanate‑induced cholestasis via regulation of the FXR pathway.
Topics: 1-Naphthylisothiocyanate; Animals; Chemical and Drug Induced Liver Injury; Cholestasis; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Lipopolysaccharides; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Receptors, Cytoplasmic and Nuclear; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Resveratrol ameliorates inflammatory damage and protects against osteoarthritis in a rat model of osteoarthritis.
Topics: Adenylate Kinase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Caspase 9; Drug Evaluation, Preclinical; Enzyme Induction; Gene Expression; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Osteoarthritis; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2018 |
Stable isotope labeling and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside biosynthetic pathway characterization in Fallopia multiflora.
Topics: Fallopia multiflora; Glucosides; Glycosylation; Hydroxylation; Isotope Labeling; Metabolic Networks and Pathways; Resveratrol; Stilbenes | 2018 |
Impact of the cultivation strategy on resveratrol production from glucose in engineered Corynebacterium glutamicum.
Topics: Biomass; Bioreactors; Corynebacterium glutamicum; Fermentation; Glucose; Resveratrol; Stilbenes | 2018 |
The effect of resveratrol on the developmental competence of porcine oocytes vitrified at germinal vesicle stage.
Topics: Animals; Apoptosis; Embryonic Development; Female; Glutathione; Hydrogen Peroxide; In Vitro Oocyte Maturation Techniques; Oocytes; Resveratrol; Stilbenes; Sus scrofa; Vitrification | 2018 |
Rosiglitazone is superior to resveratrol in inducing the expression of glyceroneogenic genes in adipose tissue from obese participants.
Topics: Adipose Tissue; Adult; Female; Gene Expression Regulation; Humans; Male; Middle Aged; Obesity; Pregnancy; Resveratrol; Rosiglitazone; Stilbenes; Thiazolidinediones; Tissue Culture Techniques | 2018 |
Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model.
Topics: Adult; Benzoflavones; Carbazoles; Cell Death; Female; Humans; In Situ Nick-End Labeling; Ovarian Follicle; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Tissue Culture Techniques | 2018 |
A combination of quercetin and resveratrol reduces obesity in high-fat diet-fed rats by modulation of gut microbiota.
Topics: Animals; Bacteria; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Humans; Male; Obesity; Quercetin; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Resveratrol attenuates testicular apoptosis in type 1 diabetic mice: Role of Akt-mediated Nrf2 activation and p62-dependent Keap1 degradation.
Topics: Animals; Antioxidants; Apoptosis; Diabetes Mellitus, Type 1; Kelch-Like ECH-Associated Protein 1; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Proteolysis; Proto-Oncogene Proteins c-akt; Resveratrol; Sequestosome-1 Protein; Stilbenes; Testis | 2018 |
Resveratrol dimer trans-ε-viniferin prevents rotaviral diarrhea in mice by inhibition of the intestinal calcium-activated chloride channel.
Topics: Animals; Benzofurans; Chloride Channels; Diarrhea; HT29 Cells; Humans; Intestines; Male; Mice, Inbred C57BL; Resveratrol; Rotavirus; Rotavirus Infections; Stilbenes | 2018 |
Microbial transformation of resveratrol by endophyte Streptomyces sp. A12 isolated from Polygonum cuspidatum.
Topics: Endophytes; Molecular Structure; Polygonum; Resveratrol; Spectrum Analysis; Stilbenes; Streptomyces; Transformation, Bacterial | 2018 |
Stilbenoid prenyltransferases define key steps in the diversification of peanut phytoalexins.
Topics: Amino Acid Sequence; Arachis; Biosynthetic Pathways; Dimethylallyltranstransferase; Phylogeny; Phytoalexins; Plant Roots; Resveratrol; Secondary Metabolism; Sequence Alignment; Sesquiterpenes; Stilbenes; Substrate Specificity; Transcriptome | 2018 |
Topics: Biological Availability; Dietary Carbohydrates; Gastrointestinal Microbiome; Glucosides; Humans; Hydrolysis; Lactobacillus acidophilus; Phytochemicals; Polyphenols; Resveratrol; Stilbenes | 2017 |
Effect of Chronic Administration of Resveratrol on Cognitive Performance during Aging Process in Rats.
Topics: Aging; Animals; Cognition; Drug Administration Routes; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2017 |
Resveratrol transcriptionally regulates miRNA-18a-5p expression ameliorating diabetic nephropathy via increasing autophagy.
Topics: Adenine; Animals; Ataxia Telangiectasia Mutated Proteins; Autophagy; Caspase 3; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Down-Regulation; Male; Mice; Mice, Obese; MicroRNAs; Microtubule-Associated Proteins; Resveratrol; RNA Interference; RNA, Small Interfering; Sirolimus; Stilbenes; Up-Regulation | 2017 |
Design, syntheses and lipid accumulation inhibitory activities of novel resveratrol mimics.
Topics: 3T3-L1 Cells; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Gene Expression Profiling; HEK293 Cells; Humans; Lipids; Mice; Molecular Structure; Resveratrol; Stilbenes; Structure-Activity Relationship | 2018 |
Release Properties and Cellular Uptake in Caco-2 Cells of Size-Controlled Chitosan Nanoparticles.
Topics: Biological Transport; Caco-2 Cells; Cells; Chemistry, Pharmaceutical; Chitosan; Coumarins; Drug Carriers; Humans; Nanoparticles; Particle Size; Resveratrol; Stilbenes; Thiazoles | 2017 |
Resveratrol strongly enhances the retinoic acid-induced superoxide generating activity via up-regulation of gp91-phox gene expression in U937 cells.
Topics: Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; NADPH Oxidase 2; Neoplasms, Experimental; Resveratrol; Stilbenes; Superoxides; Tretinoin; U937 Cells; Up-Regulation | 2018 |
Resveratrol ameliorates ionizing irradiation-induced long-term immunosuppression in mice.
Topics: Animals; Cytokines; Immune Tolerance; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Radiation-Protective Agents; Resveratrol; Spleen; Stilbenes; Thymus Gland; Whole-Body Irradiation | 2018 |
Resveratrol Intake During Pregnancy and Lactation Modulates the Early Metabolic Effects of Maternal Nutrition Differently in Male and Female Offspring.
Topics: Animal Nutritional Physiological Phenomena; Animals; Eating; Female; Lactation; Male; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Resveratrol; Sex Characteristics; Stilbenes | 2018 |
The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction.
Topics: Animals; Cell Differentiation; Cell Line; Glucose; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Diseases; Myoblasts, Skeletal; Resveratrol; Stilbenes | 2018 |
Resveratrol-induced thrombocytopenia: Inadvertent side-effect of a commonly used antioxidant.
Topics: Adult; Antioxidants; Female; Humans; Melanosis; Neurocutaneous Syndromes; Platelet Count; Resveratrol; Stilbenes; Thrombocytopenia | 2018 |
Effects of nutraceuticals on anaplastic thyroid cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Catechin; Cell Differentiation; Cell Growth Processes; Cell Line, Tumor; Curcumin; Dietary Supplements; Genistein; Humans; MicroRNAs; Resveratrol; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms | 2018 |
Resveratrol Ameliorates Mitochondrial Elongation via Drp1/Parkin/PINK1 Signaling in Senescent-Like Cardiomyocytes.
Topics: Animals; Calcium; Cell Line; Cellular Senescence; Dynamins; Galactose; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mitochondrial Proteins; Mitophagy; Myocytes, Cardiac; Phosphorylation; Protein Kinases; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Ubiquitin-Protein Ligases; Up-Regulation | 2017 |
Effect of Glycine, Pyruvate, and Resveratrol on the Regeneration Process of Postischemic Intestinal Mucosa.
Topics: Animals; beta-Fructofuranosidase; Cell Proliferation; Disease Models, Animal; Glycine; Injections, Intravenous; Intestinal Mucosa; Intestine, Small; Ki-67 Antigen; Mesenteric Arteries; Pyruvic Acid; Rats; Regeneration; Reperfusion Injury; Resveratrol; Stilbenes | 2017 |
Resveratrol attenuates hydrogen peroxide‑induced apoptosis, reactive oxygen species generation, and PSGL‑1 and VWF activation in human umbilical vein endothelial cells, potentially via MAPK signalling pathways.
Topics: Antioxidants; Apoptosis; Caspase 3; Cell Survival; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; MAP Kinase Signaling System; Membrane Glycoproteins; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; von Willebrand Factor | 2018 |
Resveratrol Does Not Protect from Ischemia-Induced Acute Kidney Injury in an in Vivo Rat Model.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Ischemia; Rats; Reperfusion Injury; Resveratrol; Sirtuin 1; Stilbenes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Resveratrol mitigates trophoblast and endothelial dysfunction partly via activation of nuclear factor erythroid 2-related factor-2.
Topics: Activins; Antioxidants; Endothelial Cells; Female; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; NF-E2-Related Factor 2; Oxidative Stress; Pre-Eclampsia; Pregnancy; Resveratrol; Stilbenes; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1 | 2017 |
Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Cardiomyopathies; Disease Models, Animal; GPI-Linked Proteins; Heart; Hemochromatosis Protein; Hepcidins; Humans; Iron; Iron Overload; Membrane Proteins; Mice; Myocardium; Oxidative Stress; Protein Kinases; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium-Calcium Exchanger; Stilbenes | 2018 |
Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; ATP-Binding Cassette Transporters; Azithromycin; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Glutathione; Hepatocytes; Humans; Liver; Male; Pregnane X Receptor; Rats; Rats, Wistar; Receptors, Steroid; Resveratrol; Stilbenes | 2017 |
Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.
Topics: Animals; Blood Glucose; Body Weight; Caveolin 1; Diet, High-Fat; Down-Regulation; HEK293 Cells; Humans; Kruppel-Like Transcription Factors; Lipids; Liver; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Transcription, Genetic; Transforming Growth Factor beta | 2017 |
Autophagy plays a protective role in Mn-induced toxicity in PC12 cells.
Topics: Acetylcysteine; Animals; Autophagy; Cell Respiration; Chlorides; Chloroquine; Dopamine; Manganese Compounds; Mitochondria; Neurosecretory Systems; Oxidative Stress; PC12 Cells; Rats; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced glycation end products in glomeruli and tubules of rat kidneys.
Topics: Animals; Antioxidants; Diabetes Mellitus, Type 1; DNA Damage; Glycation End Products, Advanced; Kidney Glomerulus; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2018 |
Efficiency of resveratrol-loaded sericin nanoparticles: Promising bionanocarriers for drug delivery.
Topics: Anti-Inflammatory Agents; Antioxidants; Caco-2 Cells; Cell Line; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Fibroblasts; Humans; Nanoparticles; Particle Size; Polyphenols; Resveratrol; Sericins; Silk; Solubility; Stilbenes | 2018 |
Resveratrol and/or exercise training counteract aging-associated decline of physical endurance in aged mice; targeting mitochondrial biogenesis and function.
Topics: Aging; Animals; Antioxidants; Gene Expression Regulation; Mice; Mitochondria, Muscle; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Physical Endurance; Resveratrol; Stilbenes | 2018 |
Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice.
Topics: Animals; Glucuronides; Glucuronosyltransferase; Mice; Resveratrol; Stilbenes; Sulfotransferases; Tissue Distribution | 2017 |
Effects of Resveratrol, Lovastatin and the mTOR-Inhibitor RAD-001 on Insulin-Induced Genomic Damage In Vitro.
Topics: Animals; Cell Survival; Cells, Cultured; Diabetes Mellitus; DNA Damage; Epithelial Cells; Everolimus; Humans; Insulin; Kidney; Lovastatin; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases | 2017 |
CACUL1 reciprocally regulates SIRT1 and LSD1 to repress PPARγ and inhibit adipogenesis.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Carrier Proteins; Cell Differentiation; Co-Repressor Proteins; Cullin Proteins; Epigenesis, Genetic; HCT116 Cells; HEK293 Cells; Histone Demethylases; Histones; Humans; Mice; PPAR gamma; Resveratrol; Sequence Analysis, RNA; Signal Transduction; Sirtuin 1; Stilbenes | 2017 |
Anticancer effects of resveratrol in canine hemangiosarcoma cell lines.
Topics: Analysis of Variance; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Anura; Apoptosis; Cell Line, Tumor; Dog Diseases; Dogs; Doxorubicin; Hemangiosarcoma; Resveratrol; Stilbenes | 2018 |
Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells.
Topics: Cadherins; Carcinoma, Renal Cell; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Vimentin | 2018 |
Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cyclooxygenase 2; Enzyme Induction; Gene Knockdown Techniques; Humans; Male; MAP Kinase Signaling System; Microscopy, Confocal; Phosphorylation; Prostatic Neoplasms; Protein Transport; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Small Interfering; Stilbenes; SUMO-1 Protein; Sumoylation; Tumor Suppressor Protein p53 | 2018 |
Co-encapsulation of curcumin and resveratrol into novel nutraceutical hyalurosomes nano-food delivery system based on oligo-hyaluronic acid-curcumin polymer.
Topics: Antioxidants; Biphenyl Compounds; Curcumin; Dietary Supplements; Drug Compounding; Drug Liberation; Food; Free Radical Scavengers; Hyaluronic Acid; Nanoparticles; Particle Size; Picrates; Polymers; Proton Magnetic Resonance Spectroscopy; Resveratrol; Stilbenes | 2018 |
Effect of storage tube material and resveratrol during liquid storage of matured bovine oocytes on subsequent development.
Topics: Animals; Antioxidants; Blastocyst; Cattle; Fertilization in Vitro; In Vitro Oocyte Maturation Techniques; Oocytes; Resveratrol; Stilbenes; Tissue Preservation | 2017 |
Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1.
Topics: Animals; Benzamides; Brain Injuries, Traumatic; Caspase 1; Cerebral Cortex; Cytokines; Glutathione; Inflammasomes; Male; Malondialdehyde; Naphthols; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Superoxide Dismutase | 2018 |
Resveratrol alleviates lysophosphatidylcholine-induced damage and inflammation in vascular endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Cell Line; DNA, Complementary; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Interleukin-6; L-Lactate Dehydrogenase; Lysophosphatidylcholines; Models, Cardiovascular; Myeloid Differentiation Factor 88; NF-kappa B; Resveratrol; RNA, Small Interfering; Signal Transduction; Stilbenes; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Orthogonal Array composite design to study and optimize antioxidant combinations in the prevention of UVB-induced HSF damage.
Topics: Antioxidants; Cell Line; Cell Survival; Curcumin; DNA Fragmentation; Fibroblasts; Flavanones; Humans; Linear Models; Oxidative Stress; Proanthocyanidins; Reactive Oxygen Species; Resveratrol; Skin; Stilbenes; Ultraviolet Rays | 2018 |
[Effect of high glucose-based peritoneal dialysis fluids on NLRP3-IL-1β in human peritoneal mesothelial cells].
Topics: Autophagy; Blotting, Western; Carrier Proteins; Cell Line; Dialysis Solutions; Glucose; Humans; Inflammasomes; Inflammation; Interleukin-1beta; Mitochondria; NLR Family, Pyrin Domain-Containing 3 Protein; Peritoneal Dialysis; Peritoneum; Reactive Oxygen Species; Resveratrol; Stilbenes | 2017 |
Resveratrol and pinostilbene confer neuroprotection against aging-related deficits through an ERK1/2-dependent mechanism.
Topics: Aging; Animals; Cell Line; Dopamine; Dopaminergic Neurons; Humans; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Motor Activity; Neurons; Neuroprotective Agents; Resveratrol; Stilbenes; Substantia Nigra | 2018 |
Resveratrol-Induced Changes in MicroRNA Expression in Primary Human Fibroblasts Harboring Carnitine-Palmitoyl Transferase-2 Gene Mutation, Leading to Fatty Acid Oxidation Deficiency.
Topics: Carnitine O-Palmitoyltransferase; Case-Control Studies; Fibroblasts; Gene Expression Regulation; Humans; Metabolism, Inborn Errors; MicroRNAs; Mitochondria; Molecular Sequence Annotation; Mutation; Primary Cell Culture; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Apoptosis induction and inhibition of HeLa cell proliferation by alpha-naphthoflavone and resveratrol are aryl hydrocarbon receptor-independent.
Topics: Apoptosis; Benzoflavones; Cell Proliferation; CRISPR-Cas Systems; G1 Phase Cell Cycle Checkpoints; HeLa Cells; Humans; Microscopy, Confocal; Receptors, Aryl Hydrocarbon; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2018 |
Resveratrol attenuates reproductive alterations in type 1 diabetes-induced rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Epididymis; Male; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Reproduction; Resveratrol; Sperm Motility; Spermatozoa; Stilbenes; Testis | 2017 |
A Comparison of the Effectiveness of Silibinin and Resveratrol in Preventing Alpha-Amanitin-Induced Hepatotoxicity.
Topics: Alanine Transaminase; Alpha-Amanitin; Antioxidants; Aspartate Aminotransferases; Caspase 3; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Liver; Mushroom Poisoning; Nucleic Acid Synthesis Inhibitors; Protective Agents; Resveratrol; Silybin; Silymarin; Stilbenes | 2018 |
Resveratrol enhances the effects of ALA-PDT on skin squamous cells A431 through p38/ MAPK signaling pathway.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Combined Modality Therapy; Humans; MAP Kinase Signaling System; Photochemotherapy; Resveratrol; Skin Neoplasms; Stilbenes | 2018 |
DJ-1 preserving mitochondrial complex I activity plays a critical role in resveratrol-mediated cardioprotection against hypoxia/reoxygenation-induced oxidative stress.
Topics: Animals; Cardiotonic Agents; Cell Line; Electron Transport Complex I; Hypoxia; L-Lactate Dehydrogenase; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Protein Deglycase DJ-1; Rats; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; RNA, Small Interfering; Stilbenes | 2018 |
The role of resveratrol and melatonin in the nitric oxide and its oxidation products mediated functional and structural modifications of two glycolytic enzymes: GAPDH and LDH.
Topics: Animals; Antioxidants; Dithiothreitol; Enzyme Activation; Glutathione; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Kinetics; L-Lactate Dehydrogenase; Melatonin; Nitric Oxide; Oxidation-Reduction; Rabbits; Resveratrol; Stilbenes | 2018 |
Cutaneous wound healing using polymeric surgical dressings based on chitosan, sodium hyaluronate and resveratrol. A preclinical experimental study.
Topics: Animals; Bandages; Cell Line; Cell Survival; Chitosan; Drug Evaluation, Preclinical; Fibroblasts; Humans; Hyaluronic Acid; Male; Mice; Mice, Inbred ICR; Porosity; Resveratrol; Skin; Stilbenes; Surgical Wound; Wound Healing | 2018 |
Improving oral bioavailability of resveratrol by a UDP-glucuronosyltransferase inhibitory excipient-based self-microemulsion.
Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Emulsions; Excipients; Gastrointestinal Absorption; Glucuronosyltransferase; Humans; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2018 |
Stability, biocompatibility and antioxidant activity of PEG-modified liposomes containing resveratrol.
Topics: Antioxidants; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Stability; Dynamic Light Scattering; Erythrocytes; Free Radical Scavengers; Hemolysis; Humans; Liposomes; Oxidative Stress; Phospholipids; Polyethylene Glycols; Resveratrol; Stilbenes; Surface-Active Agents | 2018 |
Synergistic Promotion on Tyrosinase Inhibition by Antioxidants.
Topics: Antioxidants; Drug Synergism; Enzyme Inhibitors; Humans; Isoflavones; Kelch-Like ECH-Associated Protein 1; Melanocytes; Molecular Docking Simulation; Monophenol Monooxygenase; Phenols; Plant Extracts; Resorcinols; Resveratrol; Stilbenes; Ultraviolet Rays | 2018 |
Resveratrol Radical Repair by Vitamin C at the Micelle-Water Interface: Unexpected Reaction Rates Explained by Ion-Dipole Interactions.
Topics: Antioxidants; Ascorbic Acid; Micelles; Polyethylene Glycols; Resveratrol; Stilbenes; Surface-Active Agents; Water | 2018 |
Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke.
Topics: Acetylation; Animals; Bcl-2-Like Protein 11; Disease Models, Animal; Drug Synergism; Histone Deacetylase Inhibitors; Histones; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Promoter Regions, Genetic; Protein Binding; Resveratrol; Stilbenes; Stroke; Transcription Factor RelA; Valproic Acid | 2018 |
Tanshinol alleviates impaired bone formation by inhibiting adipogenesis via KLF15/PPARγ2 signaling in GIO rats.
Topics: Adipocytes; Adipogenesis; Animals; Body Weight; Bone Marrow; Caffeic Acids; CCAAT-Enhancer-Binding Protein-alpha; Down-Regulation; Fatty Acid-Binding Proteins; Female; Forkhead Box Protein O3; Kruppel-Like Transcription Factors; Osteogenesis; Osteoporosis; PPAR gamma; Prednisone; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Up-Regulation; Wnt Signaling Pathway | 2018 |
Resveratrol ameliorates depressive disorder through the NETRIN1-mediated extracellular signal-regulated kinase/cAMP signal transduction pathway.
Topics: Animals; Antioxidants; Cells, Cultured; Cyclic AMP; Depressive Disorder; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Hippocampus; Interleukin-17; Interleukin-1beta; Mice; Netrin-1; Neurons; Oxidative Stress; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Stilbenes; Tumor Necrosis Factor-alpha | 2018 |
High-fat Diet Mediates Anxiolytic-like Behaviors in a Time-dependent Manner Through the Regulation of SIRT1 in the Brain.
Topics: Animals; Anxiety; Blood Glucose; Body Weight; Brain; Carbazoles; Diet, High-Fat; Gene Expression Regulation; Male; Mice, Inbred C57BL; Psychotropic Drugs; Resveratrol; Sirtuin 1; Stilbenes; Time Factors | 2018 |
The in vitro radiosensitizer potential of resveratrol on MCF-7 breast cancer cells.
Topics: Antioxidants; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Humans; MCF-7 Cells; Radiation-Sensitizing Agents; Resveratrol; Signal Transduction; Stilbenes; Tumor Suppressor Protein p53 | 2018 |
Dietary Total Prenylflavonoids from the Fruits of Psoralea corylifolia L. Prevents Age-Related Cognitive Deficits and Down-Regulates Alzheimer's Markers in SAMP8 Mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animal Feed; Animals; Biomarkers; Brain; Cognitive Dysfunction; Cytokines; Disease Models, Animal; Flavonoids; Fruit; Glycogen Synthase Kinase 3 beta; Male; Mice; Molecular Structure; Peptide Fragments; Phosphorylation; Protein Aggregates; Psoralea; Resveratrol; Stilbenes; tau Proteins | 2018 |
Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells.
Topics: Animals; Biomarkers, Tumor; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; Drug Combinations; Drug Synergism; Glioblastoma; Humans; Immunophenotyping; Killer Cells, Natural; Liposomes; Lymphocytes, Tumor-Infiltrating; Macrophages; Mice; Microglia; Neoplastic Stem Cells; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Molecular Mechanism of Resveratrol's Lipid Membrane Protection.
Topics: Hydrogen Bonding; Lipid Bilayers; Molecular Dynamics Simulation; Resveratrol; Stilbenes | 2018 |
trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder.
Topics: Adrenal Glands; Analysis of Variance; Animals; Antioxidants; Anxiety; Brain-Derived Neurotrophic Factor; Corticotropin-Releasing Hormone; CREB-Binding Protein; Disease Models, Animal; Exploratory Behavior; Fear; Male; Maze Learning; Memory Disorders; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stress Disorders, Post-Traumatic | 2018 |
Preventive Effects of Resveratrol on Endocannabinoid System and Synaptic Protein Modifications in Rat Cerebral Cortex Challenged by Bilateral Common Carotid Artery Occlusion and Reperfusion.
Topics: Animals; Arterial Occlusive Diseases; Carotid Artery Diseases; Frontal Lobe; Gene Expression Regulation; Male; Oxidative Stress; Rats; Rats, Wistar; Receptors, Cannabinoid; Reperfusion Injury; Resveratrol; Stilbenes | 2018 |
Hydroxylation of Resveratrol with DoxA In Vitro: An Enzyme with the Potential for the Bioconversion of a Bioactive Stilbene.
Topics: Apigenin; Bacterial Proteins; Cytochrome P-450 Enzyme System; Doxorubicin; Ferredoxins; Flavanones; Flavones; Hydroxylation; Mixed Function Oxygenases; Models, Molecular; Molecular Docking Simulation; Oxidation-Reduction; Protein Conformation; Resveratrol; Stilbenes; Streptomyces; Substrate Specificity | 2018 |
Homocysteine-induced proliferation of vascular smooth muscle cells occurs via PTEN hypermethylation and is mitigated by Resveratrol.
Topics: Cell Line; Cell Proliferation; Cell Survival; DNA Methylation; Gene Expression Regulation; Homocysteine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PTEN Phosphohydrolase; Resveratrol; Stilbenes | 2018 |
AMPK/SIRT1/p38 MAPK signaling pathway regulates alcohol‑induced neurodegeneration by resveratrol.
Topics: AMP-Activated Protein Kinases; Animals; Ethanol; Gene Expression Regulation; Humans; Male; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Rats; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2018 |
Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice.
Topics: Acetyl-CoA Carboxylase; Animals; Benzoxazoles; Body Weight; Diabetes Mellitus; Enzyme Activators; Fatty Acid Synthases; Fatty Liver; Gene Expression Regulation; Glucose Intolerance; Heterocyclic Compounds, 4 or More Rings; Hypoglycemic Agents; Male; Metabolic Syndrome; Mice, Inbred C57BL; Molecular Docking Simulation; Resveratrol; Sirtuin 1; Sterol Regulatory Element Binding Proteins; Stilbenes | 2018 |
Comparative Study of Glyceryl Behenate or Polyoxyethylene 40 Stearate-Based Lipid Carriers for Trans-Resveratrol Delivery: Development, Characterization and Evaluation of the In Vitro Tyrosinase Inhibition.
Topics: Animals; Cell Line; Drug Carriers; Enzyme Inhibitors; Fatty Acids; Monophenol Monooxygenase; Nanostructures; Particle Size; Polyethylene Glycols; Resveratrol; Stilbenes | 2018 |
The effects of resveratrol on hepatic oxidative stress in metabolic syndrome model induced by high fructose diet.
Topics: Animals; Antioxidants; Fructose; Glutathione Peroxidase; Insulin Resistance; Liver; Male; Metabolic Syndrome; Oxidants; Oxidative Stress; Rats; Resveratrol; Stilbenes; Superoxide Dismutase | 2018 |
Improved neuroprotective effect of resveratrol nanoparticles as evinced by abrogation of rotenone-induced behavioral deficits and oxidative and mitochondrial dysfunctions in rat model of Parkinson's disease.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Male; Mitochondria; Nanoparticles; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Resveratrol; Rotenone; Stilbenes | 2018 |
ROS-driven and preferential killing of HepG2 over L-02 cells by a short-term cooperation of Cu(II) and a catechol-type resveratrol analog.
Topics: Apoptosis; Catechols; Copper; Hep G2 Cells; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
What are the chances that resveratrol will be the drug of tomorrow?
Topics: Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2018 |
Evaluation of the treatment with resveratrol-loaded nanoparticles in intestinal injury model caused by ischemia and reperfusion.
Topics: Animals; Antioxidants; Drug Carriers; Gastrointestinal Transit; Ileum; Intestinal Diseases; Male; Nanoparticles; Oxidative Stress; Particle Size; Rats; Rats, Wistar; Reperfusion Injury; Resveratrol; Stilbenes | 2018 |
Resveratrol liposomes and lipid nanocarriers: Comparison of characteristics and inducing browning of white adipocytes.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Animals; Biomarkers; Calorimetry, Differential Scanning; Cell Death; Drug Carriers; Drug Liberation; Gene Expression Regulation; Genes, Reporter; Lipids; Liposomes; Mice; Nanoparticles; Organelle Biogenesis; PPAR gamma; Resveratrol; RNA, Messenger; Spectrum Analysis, Raman; Stilbenes; X-Ray Diffraction | 2018 |
ROS responsive resveratrol delivery from LDLR peptide conjugated PLA-coated mesoporous silica nanoparticles across the blood-brain barrier.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Cells, Cultured; Coculture Techniques; Delayed-Action Preparations; Endothelial Cells; Nanoparticles; Peptides; Polyesters; Rats; Reactive Oxygen Species; Receptors, LDL; Resveratrol; Silicon Dioxide; Stilbenes | 2018 |
Resveratrol protects against sodium nitroprusside induced nucleus pulposus cell apoptosis by scavenging ROS.
Topics: Animals; Antioxidants; Apoptosis; Cells, Cultured; Nitric Oxide Donors; Nitroprusside; Nucleus Pulposus; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
Metabolomics Reveals Protection of Resveratrol in Diet-Induced Metabolic Risk Factors in Abdominal Muscle.
Topics: Abdominal Muscles; Amino Acids; Animals; Apolipoproteins E; Atherosclerosis; Carbohydrate Metabolism; Diet, High-Fat; Discriminant Analysis; Gas Chromatography-Mass Spectrometry; Least-Squares Analysis; Lipid Metabolism; Lipids; Metabolic Diseases; Mice; Mice, Knockout; Microscopy, Electron; Monosaccharides; Resveratrol; Risk Factors; Stilbenes | 2018 |
Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Cardiotoxicity; Cell Line; Diterpenes; Epoxy Compounds; Female; Forkhead Box Protein O3; Heart Diseases; Humans; Male; Mice; Mice, Inbred BALB C; Myocardium; Myocytes, Cardiac; Phenanthrenes; Resveratrol; Signal Transduction; Sirtuin 3; Stilbenes | 2016 |
Enhancement of
Topics: Adult; Anti-Inflammatory Agents; Antioxidants; Chemistry, Pharmaceutical; Drug Stability; Emulsions; Female; Humans; Hydrogels; Lipids; Male; Microscopy; Microspheres; Phosphatidylcholines; Photolysis; Resveratrol; Skin Cream; Stilbenes; Surface-Active Agents; Triglycerides; Young Adult | 2017 |
Nanoliposomal Resveratrol as a Novel Approach to Treatment of Diabetes Mellitus.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Drug Delivery Systems; Insulin; Liposomes; Nanoparticles; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2018 |
Resveratrol Improves Endothelial Progenitor Cell Function through miR-138 by Targeting Focal Adhesion Kinase (FAK) and Promotes Thrombus Resolution In Vivo.
Topics: Adult; Animals; Cell Movement; Endothelial Progenitor Cells; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; MicroRNAs; Neovascularization, Physiologic; Rats, Nude; Resveratrol; Stilbenes; Thrombosis; Up-Regulation | 2018 |
Resveratrol's Hidden Hand: A Route to the Optical Detection of Biomolecular Binding.
Topics: Binding Sites; Circular Dichroism; Humans; Molecular Structure; Optical Imaging; Quantum Theory; Resveratrol; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Stereoisomerism; Stilbenes; Tyrosine-tRNA Ligase | 2018 |
Dermal anti-oxidant, anti-inflammatory and anti-aging effects of Compritol ATO-based Resveratrol colloidal carriers prepared using mixed surfactants.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colloids; Dermatologic Agents; Dermis; Drug Carriers; Drug Compounding; Drug Liberation; Excipients; Fatty Acids; Male; Models, Animal; Particle Size; Rats; Rats, Wistar; Resveratrol; Skin Aging; Stilbenes; Surface-Active Agents; Ultraviolet Rays | 2018 |
Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro.
Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Colorectal Neoplasms; Fatty Acids, Omega-3; HCT116 Cells; HT29 Cells; Humans; Nanoparticles; Rats; Resveratrol; Stearic Acids; Stilbenes | 2018 |
Protective effects and immunomodulation on piglets infected with rotavirus following resveratrol supplementation.
Topics: Animals; Cytokines; Diarrhea; Oxidative Stress; Resveratrol; Rotavirus Infections; Stilbenes; Swine; Swine Diseases; T-Lymphocyte Subsets | 2018 |
FOXO1, a Potential Therapeutic Target, Regulates Autophagic Flux, Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in Human Cholangiocarcinoma QBC939 Cells.
Topics: Acetylation; Apoptosis; Autophagy; Autophagy-Related Protein 7; Bile Duct Neoplasms; Cell Line, Tumor; Cholangiocarcinoma; Forkhead Box Protein O1; Humans; Membrane Potential, Mitochondrial; Microtubule-Associated Proteins; Oxidative Stress; Resveratrol; RNA Interference; RNA, Small Interfering; Sequestosome-1 Protein; Stilbenes | 2018 |
Resveratrol Attenuates Cognitive Deficits of Traumatic Brain Injury by Activating p38 Signaling in the Brain.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Injuries, Traumatic; Cognition; Cognitive Dysfunction; Female; Male; MAP Kinase Signaling System; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes | 2018 |
Quantification of desoxyrhapontigenin (4-methoxyresveratrol) in rat plasma by LC-MS/MS: Application to pre-clinical pharmacokinetic study.
Topics: Administration, Oral; Animals; Biological Availability; Chromatography, Liquid; Infusions, Intravenous; Male; Plasma; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2018 |
Resveratrol protects late endothelial progenitor cells from TNF-α-induced inflammatory damage by upregulating Krüppel-like factor-2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Endothelial Progenitor Cells; Female; Gene Expression Regulation; Inflammation; Intercellular Adhesion Molecule-1; Kruppel-Like Transcription Factors; Male; Neovascularization, Physiologic; Nitric Oxide; Rats; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2018 |
Resveratrol and Pterostilbene Exhibit Anticancer Properties Involving the Downregulation of HPV Oncoprotein E6 in Cervical Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle Checkpoints; DNA-Binding Proteins; Down-Regulation; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Oncogene Proteins, Viral; Polyphenols; Repressor Proteins; Resveratrol; Stilbenes; Tumor Suppressor Protein p53; Up-Regulation; Uterine Cervical Neoplasms | 2018 |
Resveratrol Alleviates Inflammatory Responses and Oxidative Stress in Rat Kidney Ischemia-Reperfusion Injury and H2O2-Induced NRK-52E Cells via the Nrf2/TLR4/NF-κB Pathway.
Topics: Animals; Caspase 3; Cell Line; Cell Survival; Cytokines; Disease Models, Animal; Hydrogen Peroxide; Kidney; Male; Matrix Metalloproteinase 13; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; RNA Interference; Signal Transduction; Stilbenes; Superoxide Dismutase; Toll-Like Receptor 4 | 2018 |
Resveratrol combined with total flavones of hawthorn alleviate the endothelial cells injury after coronary bypass graft surgery.
Topics: Animals; Aspirin; Coronary Artery Bypass; Crataegus; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Flavones; Intercellular Adhesion Molecule-1; Rabbits; Resveratrol; Stilbenes | 2018 |
Synthetic resveratrol-curcumin hybrid derivative inhibits mitosis progression in estrogen positive MCF-7 breast cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Aurora Kinase A; Breast Neoplasms; Cell Cycle Proteins; Cell Line; Cell Survival; Curcumin; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Drug Combinations; Estrogens; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; MCF-7 Cells; Mitosis; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Resveratrol; Stilbenes | 2018 |
Correlation of ARHI upregulation with growth suppression and STAT3 inactivation in resveratrol-treated ovarian cancer cells.
Topics: Antioxidants; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Resveratrol; rho GTP-Binding Proteins; STAT3 Transcription Factor; Stilbenes; Up-Regulation | 2018 |
Behavioral alterations in autism model induced by valproic acid and translational analysis of circulating microRNA.
Topics: Adolescent; Animals; Anticonvulsants; Antioxidants; Autistic Disorder; Behavior, Animal; Child; Child, Preschool; Circulating MicroRNA; Disease Models, Animal; Female; Humans; Male; Maternal Exposure; MicroRNAs; Pregnancy; Prenatal Exposure Delayed Effects; Protein Biosynthesis; Rats, Wistar; Resveratrol; Stilbenes; Valproic Acid | 2018 |
Resveratrol Inhibits Porcine Intestinal Glucose and Alanine Transport: Potential Roles of Na⁺/K⁺-ATPase Activity, Protein Kinase A, AMP-Activated Protein Kinase and the Association of Selected Nutrient Transport Proteins with Detergent Resistant Membranes
Topics: Alanine; AMP-Activated Protein Kinases; Animals; Cell Membrane; Chlorides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucose; Ileum; In Vitro Techniques; Ion Pumps; Jejunum; Membrane Potentials; Peptide Transporter 1; Phosphorylation; Resveratrol; Sodium-Glucose Transporter 1; Sodium-Hydrogen Exchanger 3; Sodium-Potassium-Exchanging ATPase; Stilbenes; Sus scrofa | 2018 |
Resveratrol stimulates c-Fos gene transcription via activation of ERK1/2 involving multiple genetic elements.
Topics: Caco-2 Cells; Enzyme Activation; Gene Expression Regulation; Genes, fos; HEK293 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Response Elements; Resveratrol; Signal Transduction; Stilbenes; Transcriptional Activation | 2018 |
Early potential effects of resveratrol supplementation on skeletal muscle adaptation involved in exercise-induced weight loss in obese mice.
Topics: Animals; Diet, High-Fat; Glucose; Homeostasis; Lipids; Male; Mice; Mice, Inbred ICR; Mice, Obese; Muscle, Skeletal; Obesity; Physical Conditioning, Animal; Resveratrol; Stilbenes; Transcription Factors; Weight Loss | 2018 |
The Synergistic Neuroprotective Effects of Combined Rosuvastatin and Resveratrol Pretreatment against Cerebral Ischemia/Reperfusion Injury.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Proteins; Brain; Cytoprotection; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Inflammation Mediators; Male; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Rosuvastatin Calcium; Signal Transduction; Stilbenes | 2018 |
Pomegranate Seed Oil Enhances the Percutaneous Absorption of trans-Resveratrol.
Topics: Animals; Biological Transport; Fatty Acids, Unsaturated; In Vitro Techniques; Lythraceae; Palmitates; Plant Oils; Resveratrol; Seeds; Skin; Skin Absorption; Stilbenes; Stimulation, Chemical; Swine | 2018 |
High glucose causes vascular dysfunction through Akt/eNOS pathway: reciprocal modulation by juglone and resveratrol.
Topics: Acetylcholine; Animals; Aorta; Endothelium, Vascular; Fructose; Gene Expression Regulation; Glucose; In Vitro Techniques; Male; Naphthoquinones; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; Resveratrol; Signal Transduction; Stilbenes; Vasodilation | 2018 |
Can the quorum sensing inhibitor resveratrol function as an aminoglycoside antibiotic accelerant against Pseudomonas aeruginosa?
Topics: Aminoglycosides; Anti-Bacterial Agents; Biofilms; Drug Synergism; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Pseudomonas aeruginosa; Quorum Sensing; Resveratrol; Stilbenes | 2018 |
Combinatorial Preconditioning of Rat Brain Cultures with Subprotective Ethanol and Resveratrol Concentrations Promotes Synergistic Neuroprotection.
Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Brain; Cells, Cultured; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Contamination; Ethanol; Female; Male; Neuroglia; Neurons; Peptide Fragments; Rats; Resveratrol; Stilbenes | 2018 |
Going through the wine fining: Intimate dialogue between organics and clays.
Topics: Bentonite; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Polyphenols; Resveratrol; Stilbenes; Wine; X-Ray Diffraction | 2018 |
Resveratrol regulates hyperglycemia-induced modulations in experimental diabetic animal model.
Topics: Animals; Antioxidants; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Hyperglycemia; Insulin; Insulin Resistance; Magnesium; Male; Metformin; Rats; Resveratrol; Stilbenes; Vitamin E | 2018 |
Nocturnal resveratrol administration inhibits chemically induced breast cancer formation in rats.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cytokines; Drug Administration Schedule; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Period Circadian Proteins; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Burden | 2017 |
Switching glycosyltransferase UGT
Topics: Bacillus licheniformis; Bacterial Proteins; Glucosides; Glucosyltransferases; Glycosylation; Kinetics; Mutation; Protein Engineering; Resveratrol; Stilbenes | 2018 |
High fat diet and high polyphenols beverages effects in enzymatic and non-enzymatic antioxidant activity.
Topics: Animals; Antioxidants; Beverages; Catalase; Diet, High-Fat; Female; Glutathione Peroxidase; Polyphenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Superoxide Dismutase | 2017 |
Gut microbiota analysis of juvenile genetically improved farmed tilapia (Oreochromis niloticus) by dietary supplementation of different resveratrol concentrations.
Topics: Animal Feed; Animals; Cichlids; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Gastrointestinal Microbiome; Male; Random Allocation; Resveratrol; Stilbenes | 2018 |
Resveratrol influences platinum pharmacokinetics: A novel mechanism in protection against cisplatin-induced nephrotoxicity.
Topics: Amidinotransferases; Animals; Antineoplastic Agents; Cisplatin; Kidney; Male; Nitric Oxide Synthase Type III; Platinum; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2018 |
Preparation and in vitro-in vivo characterization of trans-resveratrol nanosuspensions.
Topics: Animals; Antioxidants; Biological Availability; Drug Liberation; Nanoparticles; Particle Size; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes; Suspensions | 2018 |
Resveratrol-cyclodextrin complex affects the expression of genes associated with lipid metabolism in bovine in vitro produced embryos.
Topics: Animals; Cattle; Cyclodextrins; Dose-Response Relationship, Drug; Embryo Culture Techniques; Embryo, Mammalian; Gene Expression Regulation, Developmental; In Vitro Oocyte Maturation Techniques; Lipid Metabolism; Oocytes; Resveratrol; Stilbenes | 2018 |
Resveratrol Suppresses the Growth and Enhances Retinoic Acid Sensitivity of Anaplastic Thyroid Cancer Cells.
Topics: Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Resveratrol; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Tretinoin; Up-Regulation | 2018 |
Resveratrol protects HaCaT cells from ultraviolet B-induced photoaging via upregulation of HSP27 and modulation of mitochondrial caspase-dependent apoptotic pathway.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line; Cell Survival; Cellular Senescence; Cytoprotection; Gene Silencing; HSP27 Heat-Shock Proteins; Humans; Mitochondria; Resveratrol; RNA, Small Interfering; Signal Transduction; Skin Aging; Stilbenes; Ultraviolet Rays; Up-Regulation | 2018 |
Repair Activity of trans-Resveratrol toward 2'-Deoxyguanosine Radicals.
Topics: Deoxyguanosine; Electron Transport; Free Radicals; Kinetics; Quantum Theory; Resveratrol; Stereoisomerism; Stilbenes | 2018 |
Resveratrol decreases Rad51 expression and sensitizes cisplatin‑resistant MCF‑7 breast cancer cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cisplatin; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; MCF-7 Cells; Phosphorylation; Rad51 Recombinase; Resveratrol; Stilbenes | 2018 |
Cryoprotectant choice and analyses of freeze-drying drug suspension of nanoparticles with functional stabilisers.
Topics: Antioxidants; Cryoprotective Agents; Drug Stability; Excipients; Folic Acid; Freeze Drying; Nanoparticles; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Quercetin; Resveratrol; Solubility; Stilbenes; Suspensions; Vitamin E | 2018 |
Resveratrol Attenuates Lipopolysaccharides (LPS)-Induced Inhibition of Osteoblast Differentiation in MC3T3-E1 Cells.
Topics: 3T3 Cells; Animals; Apoptosis; Cell Differentiation; Cell Line; Cell Survival; Lipopolysaccharides; Mice; Mitochondria; Osteoblasts; Osteogenesis; Resveratrol; Stilbenes | 2018 |
Quantification of Trans-resveratrol in Red Wines Using QuEChERS Extraction Combined with Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Analytic Sample Preparation Methods; Chemical Fractionation; Chromatography, Liquid; Costs and Cost Analysis; Limit of Detection; Resveratrol; Safety; Stereoisomerism; Stilbenes; Tandem Mass Spectrometry; Wine | 2018 |
Synergistic effects of resveratrol and melatonin on in vitro maturation of porcine oocytes and subsequent embryo development.
Topics: Animals; Antioxidants; Drug Synergism; Drug Therapy, Combination; Embryo Culture Techniques; Embryonic Development; In Vitro Oocyte Maturation Techniques; Melatonin; Oocytes; Parthenogenesis; Resveratrol; Stilbenes; Swine | 2018 |
Arcopilus aureus, a Resveratrol-Producing Endophyte from Vitis vinifera.
Topics: Ascomycota; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Endophytes; Fungi; India; Plant Leaves; Plant Stems; Resveratrol; Stilbenes; Vitis | 2018 |
Alleviative effect of resveratrol on polyvinyl chloride-induced reproductive toxicity in male Wistar rats.
Topics: Animals; Antioxidants; Body Weight; Dose-Response Relationship, Drug; Enzymes; Lipid Peroxidation; Male; Polyvinyl Chloride; Rats, Wistar; Reproduction; Resveratrol; Stilbenes | 2018 |
Reply to the comments on effect of resveratrol on lipid profile: An updated systematic review and meta-analysis on randomized clinical trials.
Topics: Lipids; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2018 |
Comments on: "Effect of resveratrol on lipid profile: An updated systematic review and meta-analysis on randomized clinical trials".
Topics: Lipids; Randomized Controlled Trials as Topic; Resveratrol; Stilbenes | 2018 |
Positive effect of resveratrol against preantral follicles degeneration after ovarian tissue vitrification.
Topics: Animals; Antioxidants; Cattle; Cryopreservation; Female; Ovarian Follicle; Resveratrol; Stilbenes; Tissue Preservation; Vitrification | 2018 |
Protective effects of resveratrol against high ambient temperature-induced spleen dysplasia in broilers through modulating splenic redox status and apoptosis.
Topics: Animals; Apoptosis; Catalase; Chickens; Female; Glutathione; Glutathione Peroxidase; Hot Temperature; Male; Malondialdehyde; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Poultry Diseases; Resveratrol; Spleen; Splenic Diseases; Stilbenes; Superoxide Dismutase | 2018 |
The effect of resveratrol on glycation and oxidation products in plasma and liver of chronic methylglyoxal-treated rats.
Topics: Animals; Antioxidants; Fructosamine; Glycation End Products, Advanced; Lipid Peroxidation; Liver; Male; Oxidation-Reduction; Oxidative Stress; Protective Agents; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances | 2018 |
Resveratrol reverses the adverse effects of a diet-induced obese murine model on oocyte quality and zona pellucida softening.
Topics: Animals; Diet, High-Fat; Disease Models, Animal; Female; Humans; Meiosis; Mice; Mice, Inbred C57BL; Obesity; Oocytes; Oxidative Stress; Resveratrol; Stilbenes; Zona Pellucida | 2018 |
Molecular analysis of differential antiproliferative activity of resveratrol, epsilon viniferin and labruscol on melanoma cells and normal dermal cells.
Topics: Anticarcinogenic Agents; Benzofurans; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cyclin A; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Fibroblasts; Humans; Melanoma; Resveratrol; S Phase; Skin; Stilbenes; Vitis | 2018 |
Resveratrol alleviates LPS-induced injury in human keratinocyte cell line HaCaT by up-regulation of miR-17.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Burns; Cell Line; Cell Survival; Humans; Keratinocytes; Lipopolysaccharides; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases; Up-Regulation | 2018 |
Apoptosis induction in human breast cancer cell lines by synergic effect of raloxifene and resveratrol through increasing proapoptotic genes.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspases; Cell Line, Tumor; Cell Survival; Drug Synergism; Female; Humans; MCF-7 Cells; Nitric Oxide; Raloxifene Hydrochloride; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes | 2018 |
Resveratrol inhibits Interleukin-6 induced invasion of human gastric cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Resveratrol; Signal Transduction; Stilbenes; Stomach Neoplasms; Up-Regulation | 2018 |
Shufeng Jiedu Capsule and its active ingredients induce apoptosis, inhibit migration and invasion, and enhances doxorubicin therapeutic efficacy in hepatocellular carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Doxorubicin; Drugs, Chinese Herbal; Hep G2 Cells; Humans; Liver Neoplasms; Neoplasm Invasiveness; Quercetin; Real-Time Polymerase Chain Reaction; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Resveratrol improves uric acid-induced pancreatic β-cells injury and dysfunction through regulation of miR-126.
Topics: Animals; Cell Line, Tumor; Insulin-Secreting Cells; Kruppel-Like Transcription Factors; Mice; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation; Uric Acid | 2018 |
Resveratrol Protects Purkinje Neurons and Restores Muscle Activity in Rat Model of Cerebellar Ataxia.
Topics: Animals; Apoptosis; Cerebellar Ataxia; Male; Movement; Muscle Contraction; Muscle, Skeletal; Neuroprotective Agents; Purkinje Cells; Pyridines; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2018 |
Resveratrol prevents cognitive deficits induced by chronic unpredictable mild stress: Sirt1/miR-134 signalling pathway regulates CREB/BDNF expression in hippocampus in vivo and in vitro.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cognitive Dysfunction; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Hippocampus; Male; Maze Learning; MicroRNAs; Nootropic Agents; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Spatial Memory; Stilbenes; Stress, Psychological; Uncertainty | 2018 |
Bioavailability of Compounds Susceptible to Enzymatic Oxidation Enhances Growth of Shiitake Medicinal Mushroom (Lentinus edodes) in Solid-State Fermentation with Vineyard Prunings.
Topics: Biological Availability; Catechin; Fermentation; Laccase; Mexico; Oxidation-Reduction; Peroxidases; Phytochemicals; Plant Stems; Resveratrol; Shiitake Mushrooms; Stilbenes; Triticum; Vitis | 2018 |
Resveratrol Prevents Diabetic Cardiomyopathy by Increasing Nrf2 Expression and Transcriptional Activity.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Gene Expression Regulation; Male; Mice; NF-E2-Related Factor 2; Resveratrol; Stilbenes; Transcription, Genetic | 2018 |
Resveratrol induces dynamic changes to the microglia transcriptome, inhibiting inflammatory pathways and protecting against microglia-mediated photoreceptor apoptosis.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Movement; Lipopolysaccharides; Mice; Microglia; Models, Neurological; Nerve Degeneration; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Phagocytosis; Photoreceptor Cells, Vertebrate; Pseudopodia; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Transcriptome | 2018 |
Resveratrol Modulates Apoptosis and Autophagy Induced by High Glucose and Palmitate in Cardiac Cells.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cell Line; Diabetic Cardiomyopathies; Glucose; Hyperglycemia; Myoblasts, Cardiac; Palmitates; Rats; Resveratrol; Stilbenes | 2018 |
Resveratrol attenuates denervation-induced muscle atrophy due to the blockade of atrogin-1 and p62 accumulation.
Topics: Animals; Dietary Supplements; Humans; Mice, Inbred mdx; Muscle Denervation; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; Resveratrol; Signal Transduction; SKP Cullin F-Box Protein Ligases; Stilbenes; Transcription Factor TFIIH; Transcription Factors | 2018 |
[Inhibition analysis of resveratrol against Vibrio parahaemolyticus biofilm based on RNA-Seq technology].
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Microbial Sensitivity Tests; Resveratrol; Sequence Analysis, RNA; Stilbenes; Vibrio parahaemolyticus | 2016 |
Antioxidant activity of resveratrol ester derivatives in food and biological model systems.
Topics: Animals; Antioxidants; Cattle; Copper; Esterification; Esters; Food Additives; Free Radical Scavengers; Hydroxyl Radical; Lipoproteins, LDL; Meat; Models, Biological; Oxidation-Reduction; Resveratrol; Stilbenes | 2018 |
Improved chemical stability and cellular antioxidant activity of resveratrol in zein nanoparticle with bovine serum albumin-caffeic acid conjugate.
Topics: Antioxidants; Caffeic Acids; Drug Stability; Nanoparticles; Particle Size; Resveratrol; Serum Albumin, Bovine; Stilbenes; Zein | 2018 |
Mesenchymal stromal cells enhance the hematopoietic stem cell-supportive activity of resveratrol.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Hematopoietic Stem Cells; Humans; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mice; Proto-Oncogene Proteins c-akt; Resveratrol; Stilbenes | 2018 |
Long-Term Resveratrol Supplementation as a Secondary Prophylaxis for Stroke.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dietary Supplements; Female; Humans; Male; Resveratrol; Stilbenes; Stroke | 2018 |
Mechanism of resveratrol-induced relaxation of the guinea pig fundus.
Topics: Animals; Dose-Response Relationship, Drug; Gastric Fundus; Guinea Pigs; KATP Channels; Male; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Organ Culture Techniques; Peptides; Potassium Channel Blockers; Resveratrol; Stilbenes; Tetraethylammonium | 2018 |
Pterostilbene and 4'-Methoxyresveratrol Inhibited Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Cytokines; Inflammation; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Resveratrol; Signal Transduction; Stilbenes; Transcription Factor AP-1 | 2018 |
Does resveratrol retain its antioxidative properties in wine? Redox behaviour of resveratrol in the presence of Cu(II) and tebuconazole.
Topics: Antioxidants; Copper; Fungicides, Industrial; Mass Spectrometry; Oxidation-Reduction; Resveratrol; Stilbenes; Triazoles; Wine | 2018 |
Effects of red wine, grape juice and resveratrol consumption on bone parameters of Wistar rats submitted to high-fat diet and physical training.
Topics: Animals; Antioxidants; Beverages; Bone and Bones; Bone Density; Diet, High-Fat; Female; Physical Conditioning, Animal; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vitis; Wine | 2017 |
Efficient monooxygenase-catalyzed piceatannol production: Application of cyclodextrins for reducing product inhibition.
Topics: Bacterial Proteins; Biocatalysis; Cyclodextrins; Escherichia coli; Mixed Function Oxygenases; Pseudomonas aeruginosa; Resveratrol; Stilbenes | 2018 |
Resveratrol-Induced Downregulation of NAF-1 Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine via the ROS/Nrf2 Signaling Pathways.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Down-Regulation; Gemcitabine; Humans; Mitochondria; NF-E2-Related Factor 2; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Resveratrol; Ribonucleoproteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Stilbenes | 2018 |
Screening of melatonin, α-tocopherol, folic acid, acetyl-L-carnitine and resveratrol for anti-dengue 2 virus activity.
Topics: Acetylcarnitine; alpha-Tocopherol; Antiviral Agents; Dengue; Dengue Virus; Folic Acid; HEK293 Cells; Hep G2 Cells; Humans; Melatonin; Resveratrol; Stilbenes | 2018 |
Resveratrol prevents high-calorie diet-induced learning and memory dysfunction in juvenile C57BL/6J mice.
Topics: Animals; Biomarkers; Body Weight; CA1 Region, Hippocampal; Diet, High-Fat; Female; Learning Disabilities; Male; Maze Learning; Memory; Memory Disorders; Mice, Inbred C57BL; Neuroprotection; Nootropic Agents; Random Allocation; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Escherichia coli modular coculture system for resveratrol glucosides production.
Topics: Batch Cell Culture Techniques; Bioreactors; Biosynthetic Pathways; Biotransformation; Coculture Techniques; Coumaric Acids; DNA, Bacterial; Escherichia coli; Fermentation; Genetic Vectors; Glucosides; Glucosyltransferases; Metabolic Engineering; Resveratrol; Stilbenes; Temperature | 2018 |
Reply to Letter to the Editor "The effects of resveratrol on markers of oxidative stress in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial".
Topics: Biomarkers; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2018 |
Effect of resveratrol in type 2 diabetes oxidative stress markers: a reassessment.
Topics: Antioxidants; Biomarkers; Diabetes Mellitus, Type 2; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2018 |
[Resveratrol regulate the extracellular matrix expression via Wnt/β-catenin pathway in nucleus pulposus cells].
Topics: Aggrecans; beta Catenin; Cell Count; Cells, Cultured; Collagen Type II; Diskectomy; Extracellular Matrix; Gene Expression; Humans; Interleukin-1beta; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Nucleus Pulposus; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Combined effects of resveratrol and epigallocatechin-3-gallate on post thaw boar sperm and IVF parameters.
Topics: Animals; Catechin; Fertilization in Vitro; Male; Resveratrol; Semen Analysis; Spermatozoa; Stilbenes; Swine | 2018 |
Endothelial growth factor receptor-targeted and reactive oxygen species-responsive lung cancer therapy by docetaxel and resveratrol encapsulated lipid-polymer hybrid nanoparticles.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Compounding; Drug Liberation; Drug Synergism; Endothelial Growth Factors; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyethylene Glycols; Reactive Oxygen Species; Receptors, Vascular Endothelial Growth Factor; Resveratrol; Stearic Acids; Stilbenes; Surface Properties; Taxoids | 2018 |
Resveratrol inhibits pulmonary fibrosis by regulating miR-21 through MAPK/AP-1 pathways.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Gene Expression Regulation; Male; MAP Kinase Signaling System; MicroRNAs; Pulmonary Fibrosis; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transcription Factor AP-1 | 2018 |
Resveratrol Protects Murine Chondrogenic ATDC5 Cells Against LPS-Induced Inflammatory Injury Through Up-Regulating MiR-146b.
Topics: Animals; Cell Line; Chondrocytes; Cytokines; Inflammation; Lipopolysaccharides; MAP Kinase Signaling System; Mice; MicroRNAs; Resveratrol; Stilbenes; Up-Regulation | 2018 |
Alleviation of Acute Lung Injury in Rats with Sepsis by Resveratrol via the Phosphatidylinositol 3-Kinase/Nuclear Factor-Erythroid 2 Related Factor 2/Heme Oxygenase-1 (PI3K/Nrf2/HO-1) Pathway.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Heme Oxygenase-1; Interleukin-10; Interleukin-18; Male; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylinositol 3-Kinase; Random Allocation; Rats; Rats, Wistar; Resveratrol; Sepsis; Signal Transduction; Stilbenes | 2018 |
Resveratrol inhibits angiotensin II‑induced proliferation of A7r5 cells and decreases neointimal hyperplasia by inhibiting the CaMKII‑HDAC4 signaling pathway.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Cycle; Cell Line; Histone Deacetylases; Hyperplasia; Male; Neointima; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Resveratrol promotes the embryonic development of vitrified mouse oocytes after in vitro fertilization.
Topics: Animals; Blastocyst; Cell Survival; Cryopreservation; Embryo Culture Techniques; Female; Fertilization in Vitro; Glutathione; Mice; Mitochondria; Oocytes; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Vitrification | 2018 |
Resveratrol Improves Tube Formation in AGE-Induced Late Endothelial Progenitor Cells by Suppressing Syndecan-4 Shedding.
Topics: Antigens, CD34; Cells, Cultured; Endothelial Progenitor Cells; Glycation End Products, Advanced; Humans; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Syndecan-4 | 2018 |
Comparative study of transdermal drug delivery systems of resveratrol: High efficiency of deformable liposomes.
Topics: Administration, Cutaneous; Drug Delivery Systems; Dynamic Light Scattering; Ethanol; Liposomes; Microscopy, Electron, Transmission; Nanoparticles; Polysorbates; Resveratrol; Skin Absorption; Spectrum Analysis, Raman; Stilbenes | 2018 |
Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21.
Topics: Cell Line; Cell Movement; Glycolysis; Humans; Hydrogen Peroxide; MicroRNAs; Pancreatic Stellate Cells; Reactive Oxygen Species; Resveratrol; Stilbenes; Transfection; Up-Regulation | 2018 |
Evaluation of Oxidative Stress in Cardiomyocytes during the Aging Process in Rats Treated with Resveratrol.
Topics: Aging; Animals; Male; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2018 |
Resveratrol Can Be Stable in a Medium Containing Fetal Bovine Serum with Pyruvate but Shortens the Lifespan of Human Fibroblastic Hs68 Cells.
Topics: Animals; Catalase; Cattle; Cell Line; Cellular Senescence; Chromatography, High Pressure Liquid; Culture Media; Fibroblasts; Humans; Pyruvic Acid; Resveratrol; Serum; Stilbenes; Superoxide Dismutase | 2018 |
Resveratrol protects bupivacaine-induced neuro-apoptosis in dorsal root ganglion neurons via activation on tropomyosin receptor kinase A.
Topics: Animals; Apoptosis; Bupivacaine; Enzyme Activation; Ganglia, Spinal; Mice, Inbred C57BL; Neurons; Neuroprotection; Neuroprotective Agents; Protein Kinases; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Toward an Increased Functionality in Oyster ( Pleurotus) Mushrooms Produced on Grape Marc or Olive Mill Wastes Serving as Sources of Bioactive Compounds.
Topics: beta-Glucans; Culture Media; Ergosterol; Hydroxybenzoates; Olea; Pleurotus; Resveratrol; Stilbenes; Vitis; Waste Products | 2018 |
The effects of resveratrol on ovarian hyperstimulation syndrome in a rat model.
Topics: Animals; Antioxidants; Body Weight; Disease Models, Animal; Female; Gonadotropins, Equine; Humans; Ovarian Hyperstimulation Syndrome; Ovary; Rats; Rats, Wistar; Resveratrol; Statistics, Nonparametric; Stilbenes; Vascular Endothelial Growth Factor A | 2018 |
Resveratrol ameliorates disorders of mitochondrial biogenesis and dynamics in a rat chronic ocular hypertension model.
Topics: Animals; Antioxidants; Apoptosis; Cell Line, Tumor; Cell Survival; Intraocular Pressure; Male; Mitochondria; Mitochondrial Diseases; Ocular Hypertension; Organelle Biogenesis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Retina; Stilbenes | 2018 |
Gnetin C, a resveratrol dimer, reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ42-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzofurans; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neuroblastoma; Peptide Fragments; Resveratrol; Stilbenes | 2018 |
Antioxidant and pro-oxidant actions of resveratrol on human serum albumin in the presence of toxic diabetes metabolites: Glyoxal and methyl-glyoxal.
Topics: Antioxidants; Diabetes Mellitus; Glyoxal; Humans; Oxidants; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Reactive Oxygen Species; Resveratrol; Serum Albumin, Human; Stilbenes | 2018 |
4'-Methoxyresveratrol Alleviated AGE-Induced Inflammation via RAGE-Mediated NF-κB and NLRP3 Inflammasome Pathway.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dipterocarpaceae; Gene Expression Regulation; Glycation End Products, Advanced; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Plant Extracts; Polyphenols; RAW 264.7 Cells; Receptor for Advanced Glycation End Products; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Resveratrol promotes neuroprotection and attenuates oxidative and nitrosative stress in the small intestine in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Intestine, Small; Male; Myenteric Plexus; Neuroprotective Agents; Nitrosative Stress; Oxidative Stress; Rats, Wistar; Resveratrol; Stilbenes; Streptozocin | 2018 |
Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri.
Topics: Animals; beta-Galactosidase; Cellular Senescence; Cyprinodontiformes; Cytokines; Epithelial Cells; Intestinal Mucosa; Intestines; NF-kappa B; Phenotype; Resveratrol; Signal Transduction; Sirtuin 1; Stem Cells; Stilbenes | 2018 |
Synergistic Effects of Resveratrol and Pyrimethanil against
Topics: Botrytis; Drug Resistance, Fungal; Drug Synergism; Mycelium; Plant Diseases; Pyrimidines; Resveratrol; Spores, Fungal; Stilbenes; Vitis | 2018 |
Resveratrol induced reactive oxygen species and endoplasmic reticulum stress‑mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Endoplasmic Reticulum Stress; Humans; Melanoma; Melanoma, Cutaneous Malignant; Models, Biological; Reactive Oxygen Species; Resveratrol; Skin Neoplasms; Stilbenes | 2018 |
Enhancing the photostability and bioaccessibility of resveratrol using ovalbumin-carboxymethylcellulose nanocomplexes and nanoparticles.
Topics: Carboxymethylcellulose Sodium; Drug Carriers; Drug Compounding; Drug Stability; Light; Nanocapsules; Nanoparticles; Ovalbumin; Particle Size; Resveratrol; Stilbenes | 2018 |
[Effects of different intensities exercise combined with resveratrol on RBP4 in aged obese rats].
Topics: Aging; Animals; Insulin Resistance; Male; Obesity; Physical Conditioning, Animal; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Retinol-Binding Proteins, Plasma; Stilbenes | 2017 |
[A study on anti-arrhythmia mechanisms of resveratrol on ischemia/reperfusion in rats by regulating PI3K/Akt signaling pathway].
Topics: Animals; Arrhythmias, Cardiac; Chromones; Male; Morpholines; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Stilbenes; Ventricular Function, Left | 2017 |
[A study on preventive mechanisms of resveratrol on injuried heart during hepatic ischemia/reperfusion injury in rats by regulating Notch signaling pathway].
Topics: Animals; Cardiotonic Agents; Heart; Liver; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Resveratrol; Stilbenes | 2016 |
Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells.
Topics: 3' Untranslated Regions; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; RNA Stability; RNA, Messenger; RNA, Small Interfering; Stilbenes; Tristetraprolin | 2018 |
Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Inflammation; Male; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Spinal Cord Injuries; Stilbenes; TOR Serine-Threonine Kinases | 2018 |
Acute electrophysiologic effects of the polyphenols resveratrol and piceatannol in rabbit atria.
Topics: Animals; Atrial Fibrillation; Atrial Function; Dose-Response Relationship, Drug; Electrophysiological Phenomena; Heart Atria; Rabbits; Resveratrol; Stilbenes | 2019 |
Resveratrol Reverts Epigenetic and Transcription Changes Caused by Smoke Inhalation on Bone-Related Genes in Rats.
Topics: Animals; Bone and Bones; Bone Remodeling; Cytoprotection; Epigenesis, Genetic; Gene Expression Regulation; Inhalation Exposure; Male; Nicotiana; Osteogenesis; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tobacco Smoke Pollution | 2018 |
Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Count; Dehydroepiandrosterone; Disease Models, Animal; Drug Therapy, Combination; Female; Hormones; Lipid Peroxidation; Metformin; Ovarian Follicle; Ovarian Reserve; Ovary; Polycystic Ovary Syndrome; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Tumor Necrosis Factor-alpha; Vagina | 2018 |
Supplementation with resveratrol as Polygonum cuspidatum Sieb. et Zucc. extract induces changes in the excretion of urinary markers associated to aging in rats.
Topics: Aging; Animals; Biomarkers; Chromatography, High Pressure Liquid; Fallopia japonica; Female; Glycine; Male; Mass Spectrometry; Metabolomics; Plant Extracts; Pyridones; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2018 |
Drug Distribution and Basic Pharmacology of Paclitaxel/Resveratrol-Coated Balloon Catheters.
Topics: Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Animals; Coated Materials, Biocompatible; In Vitro Techniques; Neointima; Paclitaxel; Resveratrol; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes; Swine | 2018 |
Self-microemulsifying tablets prepared by direct compression for improved resveratrol delivery.
Topics: Aluminum Compounds; Antioxidants; Drug Compounding; Drug Delivery Systems; Drug Liberation; Emulsions; Excipients; Fatty Acids, Nonesterified; Lipase; Lipolysis; Magnesium Compounds; Resveratrol; Silicates; Silicon Dioxide; Stilbenes; Tablets | 2018 |
Resveratrol prevents nanoparticles-induced inflammation and oxidative stress via downregulation of PKC-α and NADPH oxidase in lung epithelial A549 cells.
Topics: A549 Cells; Down-Regulation; Humans; Inflammation; Lung; NADPH Oxidases; Nanoparticles; Oxidative Stress; Protein Kinase C-alpha; Reactive Oxygen Species; Resveratrol; Soot; Stilbenes | 2018 |
Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fluorouracil; HCT116 Cells; Humans; Lymphotoxin-alpha; Neoplastic Stem Cells; Phenotype; Resveratrol; Signal Transduction; Stilbenes; Tumor Microenvironment | 2018 |
Polydatin, Natural Precursor of Resveratrol, Promotes Osteogenic Differentiation of Mesenchymal Stem Cells.
Topics: Cell Differentiation; Cells, Cultured; Child; Glucosides; Humans; Male; Mesenchymal Stem Cells; Osteogenesis; Resveratrol; Stilbenes | 2018 |
Regulation of Apoptosis and Radiation Sensitization in Lung Cancer Cells via the Sirt1/NF-κB/Smac Pathway.
Topics: A549 Cells; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; DNA Damage; Gene Expression; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mitochondrial Proteins; NF-kappa B; Radiation Tolerance; Radiation, Ionizing; Resveratrol; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 1; Stilbenes | 2018 |
Production of Bioactive 3'-Hydroxystilbene Compounds Using the Flavin-Dependent Monooxygenase Sam5.
Topics: Dinitrocresols; Escherichia coli; Flavins; Glucosides; Hydroxylation; Mixed Function Oxygenases; Plant Extracts; Resveratrol; Stilbenes | 2018 |
Physiological Relevance of the Antiproliferative and Estrogenic Effects of Dietary Polyphenol Aglycones versus Their Phase-II Metabolites on Breast Cancer Cells: A Call of Caution.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Coumarins; Estrogen Antagonists; Estrogens; Female; Humans; Polyphenols; Resveratrol; Stilbenes | 2018 |
Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R.
Topics: Cell Proliferation; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Integrin alphaVbeta3; Leiomyoma; Phosphorylation; Receptor Cross-Talk; Receptor, IGF Type 1; Resveratrol; Stilbenes; Uterine Neoplasms | 2018 |
Pinosylvin enhances leukemia cell death via down-regulation of AMPKα expression.
Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Caspase 3; Down-Regulation; Gene Expression Regulation, Leukemic; Humans; Leukemia; Resveratrol; Stilbenes; THP-1 Cells; U937 Cells | 2018 |
Resveratrol sensitizes lung cancer cell to TRAIL by p53 independent and suppression of Akt/NF-κB signaling.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2018 |
Topics: Animals; Antioxidants; Cytoprotection; Models, Molecular; Molecular Conformation; Molecular Structure; Protective Agents; Rats; Resveratrol; Stilbenes | 2018 |
Resveratrol Modulates SIRT1 and DNMT Functions and Restores LINE-1 Methylation Levels in ARPE-19 Cells under Oxidative Stress and Inflammation.
Topics: Cell Line; Cell Survival; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; Epigenomics; Glucose Oxidase; Humans; Inflammation; Lipopolysaccharides; Long Interspersed Nucleotide Elements; Methylation; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes | 2018 |
Galactosylated PLGA nanoparticles for the oral delivery of resveratrol: enhanced bioavailability and in vitro anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Biological Availability; Caco-2 Cells; Drug Liberation; Endocytosis; Galactosamine; Humans; Inflammation; Intestinal Absorption; Intestinal Mucosa; Lactic Acid; Male; Nanoparticles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Resveratrol; Solubility; Stilbenes | 2018 |
t-Resveratrol Protects against Acute High Glucose Damage in Endothelial Cells.
Topics: Acetylcholine; Animals; Aorta; Blood Glucose; Cardiovascular Diseases; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Male; Nitric Oxide; Nitroprusside; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; Stilbenes; Vasodilation | 2018 |
Search of Neuroprotective Polyphenols Using the "Overlay" Isolation Method.
Topics: Amyloid beta-Peptides; Animals; Catechin; Cell Culture Techniques; Cell Differentiation; Culture Media, Serum-Free; Curcumin; Hormesis; Nerve Growth Factor; Neurons; Neuroprotective Agents; PC12 Cells; Plant Extracts; Plant Leaves; Polyphenols; Rats; Resveratrol; Sasa; Stilbenes; Taxoids | 2018 |
Modulatory Potential of Curcumin and Resveratrol on p53 Post-Translational Modifications during Gastric Cancer.
Topics: Acetylation; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinogenesis; Curcumin; Dimethylhydrazines; Drug Combinations; Male; Phosphorylation; Protein Processing, Post-Translational; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stomach Neoplasms; Tumor Suppressor Protein p53 | 2018 |
Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system.
Topics: Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Animals, Newborn; Diet, High-Fat; Female; Gene Expression Regulation; Hypolipidemic Agents; Leptin; Lipid Metabolism; Male; Maternal Nutritional Physiological Phenomena; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Resveratrol; Sirtuin 1; Stilbenes; Weaning | 2018 |
Pretreatment of nerve grafts with resveratrol improves axonal regeneration following replantation surgery for nerve root avulsion injury in rats.
Topics: Animals; Autografts; Axons; Cervical Vertebrae; Glial Cell Line-Derived Neurotrophic Factor; Male; Motor Neurons; Nerve Regeneration; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Resveratrol; Schwann Cells; Spinal Nerve Roots; Spinal Nerves; Stilbenes; Tissue Culture Techniques | 2018 |
Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Synergism; Drug Therapy, Combination; Epigenesis, Genetic; Female; Grape Seed Extract; Histone Deacetylases; Humans; MCF-7 Cells; Proanthocyanidins; Resveratrol; Stilbenes | 2018 |
Preparation and Characterization of Resveratrol Loaded Pectin/Alginate Blend Gastro-Resistant Microparticles.
Topics: 3T3-L1 Cells; Adipocytes; Alginates; Animals; Anti-Obesity Agents; Biomimetic Materials; Capsules; Cell Differentiation; Delayed-Action Preparations; Dietary Supplements; Drug Compounding; Drug Liberation; Gastric Juice; Glucuronic Acid; Hexuronic Acids; Humans; Hydrogen-Ion Concentration; Kinetics; Mice; Particle Size; Pectins; Polymethacrylic Acids; Resveratrol; Stilbenes; Triglycerides | 2018 |
Subinhibitory concentrations of resveratrol reduce alpha-hemolysin production in Staphylococcus aureus isolates by downregulating saeRS.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Down-Regulation; Gene Expression Regulation, Bacterial; Hemolysin Proteins; Humans; Methicillin-Resistant Staphylococcus aureus; Protein Kinases; Resveratrol; Staphylococcal Infections; Staphylococcus aureus; Stilbenes; Transcription Factors | 2018 |
Upregulation of PD‑L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300‑mediated NF‑κB signaling.
Topics: Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; E1A-Associated p300 Protein; Female; G1 Phase Cell Cycle Checkpoints; Histone Deacetylases; Humans; NF-kappa B; Programmed Cell Death 1 Receptor; Resveratrol; Signal Transduction; Stilbenes; Treatment Outcome; Triple Negative Breast Neoplasms; Up-Regulation | 2018 |
Fabrication of Resveratrol-Loaded Whey Protein-Dextran Colloidal Complex for the Stabilization and Delivery of β-Carotene Emulsions.
Topics: beta Carotene; Dextrans; Drug Delivery Systems; Drug Stability; Emulsions; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Osmolar Concentration; Resveratrol; Stilbenes; Whey Proteins | 2018 |
Resveratrol inhibited the progression of human hepatocellular carcinoma by inducing autophagy via regulating p53 and the phosphoinositide 3‑kinase/protein kinase B pathway.
Topics: Adenine; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Benzothiazoles; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Toluene; Tumor Suppressor Protein p53; Up-Regulation | 2018 |
Novel Approach with Controlled Nucleation and Growth for Green Synthesis of Size-Controlled Cyclodextrin-Based Metal-Organic Frameworks Based on Short-Chain Starch Nanoparticles.
Topics: Crystallization; Cyclodextrins; Drug Carriers; Green Chemistry Technology; Isomerism; Kinetics; Metal-Organic Frameworks; Nanoparticles; Particle Size; Resveratrol; Starch; Stilbenes | 2018 |
Resveratrol attenuates brain damage in permanent focal cerebral ischemia via activation of PI3K/Akt signaling pathway in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Brain Ischemia; Cyclooxygenase 2; Cytokines; Disease Models, Animal; Enzyme Activation; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Male; Neurologic Examination; Oncogene Protein v-akt; Peroxidase; Phosphatidylinositol 3-Kinase; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Signal Transduction; Stilbenes | 2018 |
Postoperative resveratrol administration improves prognosis of rat orthotopic glioblastomas.
Topics: Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Intracranial Hypertension; Neoplasm Recurrence, Local; Prognosis; Rats; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2018 |
Modular pathway engineering for resveratrol and piceatannol production in engineered Escherichia coli.
Topics: Acetyl Coenzyme A; Biosynthetic Pathways; Escherichia coli; Escherichia coli Proteins; Malonyl Coenzyme A; Metabolic Engineering; Resveratrol; Stilbenes | 2018 |
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hypertension, Pulmonary; Male; Monocrotaline; NF-kappa B; Phosphotransferases (Alcohol Group Acceptor); Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Stilbenes; Vascular Remodeling | 2018 |
Resveratrol-loaded nanoemulsion prevents cognitive decline after abdominal surgery in aged rats.
Topics: Administration, Oral; Aging; Animals; Biological Availability; Cognitive Dysfunction; Cytokines; Dose-Response Relationship, Drug; Emulsions; Hippocampus; Inflammation; Inflammation Mediators; Male; Microglia; Postoperative Complications; Rats, Wistar; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2018 |
Resveratrol and Pterostilbene, Two Analogue Phenolic Compounds, Affect Aquaglyceroporin Expression in a Different Manner in Adipose Tissue.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Aquaglyceroporins; Diet, High-Fat; Gene Expression Regulation; Male; Obesity; Rats, Wistar; Resveratrol; Stilbenes; Triglycerides | 2018 |
Antioxidant Activity and Neuroprotective Activity of Stilbenoids in Rat Primary Cortex Neurons via the PI3K/Akt Signalling Pathway.
Topics: Amyloid beta-Peptides; Animals; Antioxidants; Cell Survival; Cerebral Cortex; Gene Expression Regulation; Models, Molecular; Molecular Docking Simulation; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Stilbenes | 2018 |
Resveratrol administration increases phagocytosis, decreases oxidative burst, and promotes pro-inflammatory cytokine production in healthy dogs.
Topics: Animals; Cytokines; Dogs; Female; Immunologic Factors; Interleukin-10; Interleukin-6; Leukocytes; Male; Phagocytosis; Respiratory Burst; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2018 |
Antioxidant Properties of the Vam3 Derivative of Resveratrol.
Topics: Antioxidants; Benzofurans; Biological Products; Food Additives; Humans; Phenols; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2018 |
Alginate immobilization of Morus alba L. cell suspension cultures improved the accumulation and secretion of stilbenoids.
Topics: Acetates; Alginates; Cell Culture Techniques; Culture Media; Cyclopentanes; Disaccharides; Morus; Oxylipins; Phenylalanine Ammonia-Lyase; Plant Extracts; Plant Leaves; Resveratrol; Stilbenes; Tyrosine | 2019 |
The Effects of Resveratrol, Metformin, Cold and Strength Training on the Level of Perilipin 5 in the Heart, Skeletal Muscle and Brown Adipose Tissues in Mouse.
Topics: Adipose Tissue, Brown; Animals; Cold Temperature; Gene Expression Regulation; Lipid Metabolism; Male; Metformin; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myocardium; Perilipin-5; Physical Conditioning, Animal; Resveratrol; Stilbenes | 2018 |
Resveratrol Activated Sonic Hedgehog Signaling to Enhance Viability of NIH3T3 Cells in Vitro via Regulation of Sirt1.
Topics: Animals; Benzamides; Cell Survival; Hedgehog Proteins; Mice; Naphthols; NIH 3T3 Cells; Patched-1 Receptor; Resveratrol; Signal Transduction; Sirtuin 1; Smoothened Receptor; Stilbenes; Transcription, Genetic; Up-Regulation; Veratrum Alkaloids; Zinc Finger Protein GLI1 | 2018 |
Trans-resveratrol, but not other natural stilbenes occurring in food, carries the risk of drug-food interaction via inhibition of cytochrome P450 enzymes or interaction with xenosensor receptors.
Topics: Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Food-Drug Interactions; Hepatocytes; Humans; Receptors, Steroid; Resveratrol; Stilbenes | 2019 |
Synthesis of Piceatannol, an Oxygenated Analog of Resveratrol.
Topics: Molecular Structure; Resveratrol; Stilbenes | 2016 |
In Vitro Anticancer Properties of Table Grape Powder Extract (GPE) in Prostate Cancer.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoprevention; Colony-Forming Units Assay; Flavonoids; Histone Deacetylases; Humans; Male; Plant Extracts; Powders; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Stilbenes; Trans-Activators; Vitis; Wound Healing | 2018 |
Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Culture Media; Disaccharides; Glycosylation; Morus; Plant Extracts; Resveratrol; Stilbenes; Tissue Culture Techniques | 2019 |
Molecular cloning and functional characterization of an O-methyltransferase catalyzing 4'-O-methylation of resveratrol in Acorus calamus.
Topics: Acorus; Cloning, Molecular; Kinetics; Methylation; Methyltransferases; Plant Proteins; Resveratrol; Stilbenes | 2019 |
Structural analysis of the inhibitory effects of polyphenols, (+)-hopeaphenol and (-)-isohopeaphenol, on human SIRT1.
Topics: Humans; Phenols; Polyphenols; Protein Binding; Resveratrol; Sirtuin 1; Stilbenes | 2019 |
Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: inhibitory mechanism and structure-activity relationship.
Topics: Antioxidants; Glucosides; Glycation End Products, Advanced; Plant Extracts; Pyruvaldehyde; Resveratrol; Stilbenes; Structure-Activity Relationship | 2020 |
Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol
Topics: Apoptosis; Carcinoma, Hepatocellular; Gold; Humans; Liver Neoplasms; Metal Nanoparticles; Resveratrol; Stilbenes; Vascular Endothelial Growth Factor A | 2019 |
IL-6 in Osteoarthritis: Effects of Pine Stilbenoids.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biomarkers; Cartilage, Articular; Cell Line; Cells, Cultured; Chondrocytes; Collagen; Cytokines; Female; Gene Expression; Humans; Inflammation Mediators; Interleukin-6; Male; Matrix Metalloproteinases; Middle Aged; NF-kappa B; Osteoarthritis; Pinus; Plant Extracts; Resveratrol; Severity of Illness Index; Stilbenes; Synovial Fluid | 2018 |
Genomic sequencing, genome-scale metabolic network reconstruction, and in silico flux analysis of the grape endophytic fungus Alternaria sp. MG1.
Topics: Alternaria; Biomass; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Genome, Fungal; Mass Spectrometry; Metabolic Networks and Pathways; Propanols; Resveratrol; Stilbenes; Vitis; Whole Genome Sequencing | 2019 |
Antiproliferative activity of stilbene derivatives and other constituents from the stem bark of
Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Proliferation; Drug Screening Assays, Antitumor; Flavonoids; Hep G2 Cells; Humans; MCF-7 Cells; Morus; Plant Bark; Resveratrol; Stilbenes; Terpenes | 2020 |
Resveratrol, lunularin and dihydroresveratrol do not act as caloric restriction mimetics when administered intraperitoneally in mice.
Topics: Animals; Bibenzyls; Blood Glucose; Body Weight; Caloric Restriction; Diet, High-Fat; Eating; Gene Expression Regulation; Heme Oxygenase-1; Injections, Intraperitoneal; Insulin; Leptin; Liver; Membrane Proteins; Mice, Inbred C57BL; Phenols; Resveratrol; Sirtuin 1; Stilbenes | 2019 |
Effect of Pterostilbene, a Natural Analog of Resveratrol, on the Activity of some Antiepileptic Drugs in the Acute Seizure Tests in Mice.
Topics: Animals; Anticonvulsants; Brain Chemistry; Convulsants; Dose-Response Relationship, Drug; Electroshock; Male; Mice; Pentylenetetrazole; Psychomotor Performance; Resveratrol; Seizures; Stilbenes | 2019 |
Metabolism of Stilbenoids by Human Faecal Microbiota.
Topics: Chromatography, Liquid; Colon; Feces; Fermentation; Humans; Mass Spectrometry; Microbiota; Phenols; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2019 |
Effects of resveratrol and its analogue pterostilbene, on NOV/CCN3 adipokine in adipose tissue from rats fed a high-fat high-sucrose diet.
Topics: Adipose Tissue; Adiposity; Animals; Diet, Carbohydrate Loading; Diet, High-Fat; Immediate-Early Proteins; Male; Obesity; Rats; Rats, Wistar; Resveratrol; Stilbenes; Sucrose | 2019 |
Resveratrol analogues surprisingly effective against triple‑negative breast cancer, independent of ERα.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; DNA Repair; Estrogen Receptor alpha; Female; Humans; Resveratrol; Signal Transduction; Stilbenes; Triple Negative Breast Neoplasms | 2019 |
Hydroxystilbene Glucosides Are Incorporated into Norway Spruce Bark Lignin.
Topics: Glucosides; Lignin; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Norway; Picea; Plant Bark; Resveratrol; Stilbenes | 2019 |
Isolation and characterization of Gram-negative and Gram-positive bacteria capable of producing piceatannol from resveratrol.
Topics: Arthrobacter; Bacterial Proteins; Biocatalysis; Carbon; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydroxylation; Resveratrol; Stilbenes | 2019 |
Grape Peel Extract and Resveratrol Inhibit Wrinkle Formation in Mice Model Through Activation of Nrf2/HO-1 Signaling Pathway.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Flavonoids; Fruit; Glucosides; Heme Oxygenase-1; Humans; Mice; Mice, Hairless; NF-E2-Related Factor 2; Plant Extracts; Resveratrol; Signal Transduction; Skin Aging; Stilbenes; Ultraviolet Rays; Vitis | 2019 |
Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models.
Topics: Antioxidants; Cellular Senescence; Gene Expression Regulation; Humans; Imines; K562 Cells; Longevity; Molecular Docking Simulation; Resveratrol; Saccharomyces cerevisiae; Sirtuin 1; Stilbenes | 2019 |
Evolvement of nutraceutical onion plants engineered for resveratrol biosynthetic pathway.
Topics: Acyltransferases; Biosynthetic Pathways; Dietary Supplements; Glucosides; Onions; Plant Proteins; Plants, Genetically Modified; Resveratrol; Stilbenes; Vitis | 2019 |
Inhibiting the formation of advanced glycation end-products by three stilbenes and the identification of their adducts.
Topics: Acrolein; Glycation End Products, Advanced; Hydrogen-Ion Concentration; Plant Extracts; Pyruvaldehyde; Resveratrol; Serum Albumin, Bovine; Stilbenes; Temperature | 2019 |
Effects of Piceatannol and Resveratrol on Sirtuins and Hepatic Inflammation in High-Fat Diet-Fed Mice.
Topics: Animals; Diet, High-Fat; Humans; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Sirtuins; Stilbenes; Tumor Necrosis Factor-alpha | 2019 |
Changes in stilbene composition during postharvest ozone treatment of 'Moscato bianco' winegrapes.
Topics: Dehydration; Food Analysis; Food Handling; Food Preservation; Food Storage; Fruit; Ozone; Resveratrol; Stilbenes; Vitis | 2019 |
Divergent Effects of Resveratrol on Rat Cardiac Fibroblasts and Cardiomyocytes.
Topics: Animals; Apoptosis; Cell Death; Cell Proliferation; Cell Survival; Cells, Cultured; Estrogen Receptor alpha; Humans; Myocytes, Cardiac; Myofibroblasts; Phytoalexins; Rats; Resveratrol; Sesquiterpenes; Signal Transduction; Stilbenes; Tamoxifen | 2019 |
Stilbenoid-Mediated Epigenetic Activation of Semaphorin 3A in Breast Cancer Cells Involves Changes in Dynamic Interactions of DNA with DNMT3A and NF1C Transcription Factor.
Topics: Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Epigenesis, Genetic; Female; Gene Expression; Gene Knockdown Techniques; Gene Silencing; Homeodomain Proteins; Humans; Neoplasm Invasiveness; NFI Transcription Factors; Promoter Regions, Genetic; Resveratrol; Semaphorin-3A; Stilbenes; Transcription Factors | 2019 |
Screening and Evaluation of Xanthine Oxidase Inhibitors from
Topics: Allopurinol; Biphenyl Compounds; Enzyme Inhibitors; Free Radical Scavengers; Gnetum; High-Throughput Screening Assays; Kinetics; Least-Squares Analysis; Picrates; Plant Extracts; Resveratrol; Stilbenes; Ultrafiltration; Xanthine Oxidase | 2019 |
Topics: Animals; Antiviral Agents; Ducks; Enterovirus; Euphorbiaceae; HT29 Cells; Humans; Plant Leaves; Resveratrol; Serogroup; Stilbenes | 2021 |
Mitochondrial Ca
Topics: Adenosine Triphosphate; Animals; Calcium; Catalysis; Cell Death; Hydrolysis; Inhibitory Concentration 50; Kinetics; Magnesium; Membrane Potential, Mitochondrial; Mitochondria, Heart; Permeability; Protein Domains; Proton-Translocating ATPases; Quercetin; Resveratrol; Stilbenes; Succinic Acid; Swine | 2019 |
Regulation of resveratrol O-methyltransferase gene in pterostilbene defensing the sour rot of wine grape.
Topics: Geotrichum; Methyltransferases; Plant Diseases; Plant Proteins; Resveratrol; Secondary Metabolism; Stilbenes; Vitis | 2019 |
Isorhapontigenin, a resveratrol analogue selectively inhibits ADP-stimulated platelet activation.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Drug Evaluation, Preclinical; Female; Healthy Volunteers; Humans; Inhibitory Concentration 50; Male; Mice; Models, Animal; Molecular Docking Simulation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2Y12; Resveratrol; Signal Transduction; Stilbenes; Thrombosis | 2019 |
VqbZIP1 isolated from Chinese wild Vitis quinquangularis is involved in the ABA signaling pathway and regulates stilbene synthesis.
Topics: Abscisic Acid; Acyltransferases; Arabidopsis; Basic-Leucine Zipper Transcription Factors; Disease Resistance; Gene Expression; Gene Expression Regulation, Plant; Plant Growth Regulators; Plant Leaves; Plant Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Resveratrol; Signal Transduction; Stilbenes; Vitis | 2019 |
MTA1-Dependent Anticancer Activity of Gnetin C in Prostate Cancer.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Repressor Proteins; Resveratrol; Stilbenes; Trans-Activators | 2019 |
[Resveratrol counteracts lipopolisaccharide-mediated oxidative stress by upregulating SOCS-1 production].
Topics: Cell Line; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Stilbenes; Suppressor of Cytokine Signaling Proteins | 2019 |
The anti-biofilm and anti-virulence activities of
Topics: Bacterial Adhesion; Biofilms; Escherichia coli Proteins; Fimbriae, Bacterial; Plant Extracts; Resveratrol; Stilbenes; Uropathogenic Escherichia coli; Virulence | 2019 |
De novo transcriptome provides insights into the growth behaviour and resveratrol and trans-stilbenes biosynthesis in Dactylorhiza hatagirea - An endangered alpine terrestrial orchid of western Himalaya.
Topics: Altitude; Endangered Species; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Gene Ontology; High-Throughput Nucleotide Sequencing; Orchidaceae; Resveratrol; Seasons; Stilbenes; Temperature; Transcriptome | 2019 |
Expression of stilbene synthase VqSTS6 from wild Chinese Vitis quinquangularis in grapevine enhances resveratrol production and powdery mildew resistance.
Topics: Acyltransferases; Ascomycota; Blotting, Western; Chromatography, High Pressure Liquid; Disease Resistance; Metabolic Networks and Pathways; Phenylpropionates; Phytoalexins; Plant Diseases; Plant Proteins; Real-Time Polymerase Chain Reaction; Resveratrol; Sesquiterpenes; Stilbenes; Vitis | 2019 |
Plant-Derived Purification, Chemical Synthesis, and In Vitro/In Vivo Evaluation of a Resveratrol Dimer, Viniferin, as an HCV Replication Inhibitor.
Topics: Animals; Antiviral Agents; Benzofurans; Cell Line, Tumor; Cell Survival; Genotype; Hepacivirus; Humans; Mice; Molecular Structure; Replicon; Resveratrol; Stilbenes; Viral Nonstructural Proteins; Virus Replication; Vitis | 2019 |
Expression of CYP2S1 and CYP2W1 in breast cancer epithelial cells and modulation of their expression by synthetic methoxy stilbenes.
Topics: Breast Neoplasms; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Enzyme Induction; Epithelial Cells; Female; Humans; MCF-7 Cells; Resveratrol; Stilbenes | 2019 |
The effect of light, phenylalanine and methyl jasmonate, alone or in combination, on growth and secondary metabolism in cell suspension cultures of Vitis vinifera.
Topics: Acetates; Biosynthetic Pathways; Catechin; Cell Culture Techniques; Cell Line; Cyclopentanes; Electric Conductivity; Flavonoids; Glucosides; Hydrogen-Ion Concentration; Light; Oxylipins; Phenols; Phenylalanine; Resveratrol; Secondary Metabolism; Stilbenes; Suspensions; Vitis | 2019 |
Modulatory Role of SIRT1 and Resistin as Therapeutic Targets in Patients with Aortic Valve Stenosis.
Topics: Adult; Aged; Animals; Aortic Valve Stenosis; Biomarkers; Enzyme Inhibitors; Female; Humans; Inflammation; Leukocytes, Mononuclear; Male; Middle Aged; Resistin; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Up-Regulation | 2019 |
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA; G-Quadruplexes; Glucosides; Humans; Models, Molecular; Molecular Conformation; Proto-Oncogene Proteins c-myc; Resveratrol; Spectrum Analysis; Stilbenes; Structure-Activity Relationship | 2020 |
Resveratrol: A New Potential Therapeutic Agent for Melanoma?
Topics: Apoptosis; Humans; Melanoma; Quality of Life; Resveratrol; Skin Neoplasms; Stilbenes | 2021 |
Role of Resveratrol in Modulating microRNAs in Human Diseases: From Cancer to Inflammatory Disorder.
Topics: Anti-Inflammatory Agents; Antioxidants; Humans; MicroRNAs; Neoplasms; Resveratrol; Stilbenes | 2021 |
Influence of Resveratrol on Oxidation Processes and Lipid Phase Characteristics in Damaged Somatic Nerves.
Topics: Animals; Antioxidants; Catalase; Glutathione Peroxidase; Lipid Peroxidation; Malondialdehyde; Oxidation-Reduction; Oxidative Stress; Rats; Resveratrol; Sciatic Nerve; Stilbenes; Superoxide Dismutase | 2019 |
Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Biomarkers; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Female; Gene Expression; Humans; Molecular Structure; Neoplastic Stem Cells; Resveratrol; Stilbenes; Uterine Cervical Neoplasms | 2020 |
Role of Resveratrol in Transmitochondrial AMD RPE Cells.
Topics: Aged; Aged, 80 and over; Antioxidants; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Dietary Supplements; Epithelial Cells; Fallopia japonica; Female; Humans; Macular Degeneration; Male; Mitochondria; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Resveratrol; Retinal Pigment Epithelium; Stilbenes; Vitis | 2020 |
The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition, and the Metabolome in Mice.
Topics: Animals; Bibenzyls; Body Composition; Caloric Restriction; Dietary Supplements; Gene Expression Regulation; Glucose Tolerance Test; Glycoside Hydrolase Inhibitors; Insulin; Insulin Resistance; Leptin; Liver; Male; Metabolome; Mice, Inbred C57BL; Phenols; Resveratrol; Stilbenes | 2020 |
Resveratrol Derivative, Trans-3, 5, 4'-Trimethoxystilbene, Prevents the Developing of Atherosclerotic Lesions and Attenuates Cholesterol Accumulation in Macrophage Foam Cells.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; Cholesterol; Foam Cells; Heme Oxygenase-1; Humans; Lipoproteins, LDL; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-E2-Related Factor 2; Resveratrol; Scavenger Receptors, Class A; Stilbenes; Triggering Receptor Expressed on Myeloid Cells-1 | 2020 |
Increased mitochondrial content and function by resveratrol and select flavonoids protects against benzo[a]pyrene-induced bioenergetic dysfunction and ROS generation in a cell model of neoplastic transformation.
Topics: Benzo(a)pyrene; Flavonoids; Membrane Potential, Mitochondrial; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes | 2020 |
Exploring resveratrol dimers as virulence blocking agents - Attenuation of type III secretion in Yersinia pseudotuberculosis and Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Benzofurans; Drug Discovery; Flavonoids; Genes, Reporter; Green Fluorescent Proteins; Phenols; Pseudomonas aeruginosa; Resveratrol; Stilbenes; Type III Secretion Systems; Virulence; Yersinia pseudotuberculosis | 2020 |
The Effect of 3'-Hydroxy-3,4,5,4'-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells.
Topics: Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Humans; Kruppel-Like Factor 4; Ovarian Neoplasms; Resveratrol; Stilbenes; Transcriptome | 2020 |
A New Biosensor for Stilbenes and a Cannabinoid Enabled by Genome Mining of a Transcriptional Regulator.
Topics: Biosensing Techniques; Cannabinoids; Gene Expression Regulation; Genome, Bacterial; Metabolic Engineering; Resveratrol; Sphingomonadaceae; Stilbenes; Synthetic Biology | 2020 |
Resveratrol and its dimers ε-viniferin and δ-viniferin in red wine protect vascular endothelial cells by a similar mechanism with different potency and efficacy.
Topics: Animals; Antioxidants; Atherosclerosis; Benzofurans; Carbazoles; Catalase; Cell Line; Cell Survival; Dimerization; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation; Heme Oxygenase-1; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Protoporphyrins; Resorcinols; Resveratrol; Sirtuin 1; Stilbenes; Swine; Wine | 2020 |
Effects of Selected Resveratrol Analogues on Activation and Polarization of Lipopolysaccharide-Stimulated BV-2 Microglial Cells.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Inflammation; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Microglia; Plant Extracts; Resveratrol; Stilbenes | 2020 |
Ultrafast Nonadiabatic Photoisomerization Dynamics Mechanism for the UV Photoprotection of Stilbenoids in Grape Skin.
Topics: Density Functional Theory; Fruit; Molecular Structure; Photochemical Processes; Protective Agents; Resveratrol; Stereoisomerism; Stilbenes; Ultraviolet Rays; Vitis | 2020 |
Stability testing of resveratrol and viniferin obtained from Vitis vinifera L. by various extraction methods considering the industrial viewpoint.
Topics: Benzofurans; Chromatography, High Pressure Liquid; Mass Spectrometry; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2020 |
Maternal alcoholism and neonatal hypoxia-ischemia: Neuroprotection by stilbenoid polyphenols.
Topics: Alcohol Drinking; Alcoholism; Animals; Animals, Newborn; Brain; Brain Injuries; Cognitive Dysfunction; Female; Hypoxia; Hypoxia-Ischemia, Brain; Ischemia; Male; Maternal Nutritional Physiological Phenomena; Maternal-Fetal Exchange; Neuroprotection; Neuroprotective Agents; Polyphenols; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2020 |
Resveratrol restores intracellular transport in cystic fibrosis epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetylation; Biological Transport; Carbazoles; Cells, Cultured; Cholesterol; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Intracellular Space; Microtubules; Nose; Phosphodiesterase Inhibitors; PPAR gamma; Resorcinols; Resveratrol; Signal Transduction; Sirtuins; Stilbenes; Tubulin | 2020 |
Computational analysis of nuclear factor-κB and resveratrol in colorectal cancer.
Topics: Antioxidants; Colorectal Neoplasms; Humans; Molecular Docking Simulation; NF-kappa B; Resveratrol; Stilbenes | 2021 |
Neuroprotective Properties of Resveratrol and Its Derivatives-Influence on Potential Mechanisms Leading to the Development of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzofurans; Blood-Brain Barrier; Central Nervous System Diseases; Humans; Inflammation; Metabolic Diseases; Neuroprotection; Oxidative Stress; Resveratrol; Stilbenes; tau Proteins | 2020 |
Resveratrol transformation in red wine after heat treatment.
Topics: Alcoholic Beverages; Animals; Anti-Inflammatory Agents; Hot Temperature; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Phenols; RAW 264.7 Cells; Reactive Oxygen Species; Resveratrol; Stilbenes; Wine | 2020 |
Influence of Natural Polyphenols on Isolated Yeast Dipodascus magnusii Mitochondria.
Topics: Antioxidants; Catechin; Flavonoids; Flavonols; Microbial Sensitivity Tests; Mitochondria; Oxygen Consumption; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Saccharomycetales; Stilbenes | 2020 |
Resveratrol binds and inhibits transcription factor HIF-1α in pancreatic cancer.
Topics: Antineoplastic Agents, Phytogenic; Cell Hypoxia; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Pancreatic Neoplasms; Resveratrol; Stilbenes | 2020 |
Pterostilbene complexed with cyclodextrin exerts antimicrobial and anti-inflammatory effects.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Cell Line; Cell Survival; Cyclodextrins; Fusobacterium nucleatum; Immunologic Factors; Macrophages; Mice; Microbial Viability; NF-kappa B; Periodontitis; Polyphenols; RAW 264.7 Cells; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2020 |
Percutaneous absorption of resveratrol and its oligomers to relieve psoriasiform lesions: In silico, in vitro and in vivo evaluations.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Benzofurans; Chemistry, Pharmaceutical; Chemokines; Cytokines; Flavonoids; Glucosides; Inflammation Mediators; Keratinocytes; Mice; Phenols; Plant Extracts; Psoriasis; Resveratrol; Skin Absorption; Stilbenes; Swine | 2020 |
Total synthesis of the active resveratrol dimer dehydro-
Topics: Benzofurans; Molecular Structure; Resorcinols; Resveratrol; Stilbenes | 2020 |
Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes.
Topics: Amino Acid Chloromethyl Ketones; Antioxidants; Apoptosis; Caspase Inhibitors; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Glucosyltransferases; Humans; Inhibitory Concentration 50; Jurkat Cells; K562 Cells; PC-3 Cells; Phosphotransferases (Alcohol Group Acceptor); Resveratrol; Stilbenes; U937 Cells | 2020 |
α-Glucosidase Inhibitory Activity of Tannat Grape Phenolic Extracts in Relation to Their Ripening Stages.
Topics: alpha-Glucosidases; Anthocyanins; Antioxidants; Biocatalysis; Chromatography, High Pressure Liquid; Flavonoids; Glycoside Hydrolase Inhibitors; Kinetics; Mass Spectrometry; Molecular Structure; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Vitis | 2020 |
Effect of methoxy stilbenes-analogs of resveratrol-on the viability and induction of cell cycle arrest and apoptosis in human myeloid leukemia cells.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Cycle Checkpoints; Cell Survival; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Leukemia, Myeloid; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2020 |
Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells.
Topics: Cell Line; Cell Proliferation; CRISPR-Cas Systems; DNA Replication; Drug Resistance; Humans; Hydroxyurea; Jurkat Cells; Nucleotides; Resveratrol; S Phase Cell Cycle Checkpoints; Sirtuin 1; Stilbenes | 2020 |
Effects of grape juice, red wine and resveratrol on liver parameters of rat submitted high-fat diet.
Topics: Animals; Diet, High-Fat; Female; Fruit and Vegetable Juices; Liver; Rats; Rats, Wistar; Resveratrol; Stilbenes; Vitis; Wine | 2020 |
Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts.
Topics: Cell Proliferation; Cells, Cultured; Cellular Senescence; Fibroblasts; Humans; Resveratrol; Sirtuin 1; Stilbenes | 2020 |
Liposomes as carriers of resveratrol and vitamin E: Evaluating ameliorative antioxidant effect using chemical and cellular test systems.
Topics: Antioxidants; Ascorbic Acid; Endothelial Cells; Humans; Hydrogen Peroxide; Liposomes; Luminol; Oxygen; Reactive Oxygen Species; Resveratrol; Stilbenes; Vitamin E; Vitamins | 2022 |
Screening of an Endophyte Transforming Polydatin to Resveratrol from
Topics: Antioxidants; Chromatography, High Pressure Liquid; Endophytes; Glucosides; Mass Spectrometry; Polygonaceae; Resveratrol; Rhizome; RNA, Ribosomal, 16S; Stilbenes | 2020 |
The protective effect of stilbenes resveratrol and pterostilbene individually and combined with mycotoxin citrinin in human adenocarcinoma HT-29 cell line
Topics: Antioxidants; Apoptosis; Cell Membrane; Cell Survival; Citrinin; Dose-Response Relationship, Drug; Drug Interactions; HT29 Cells; Humans; Oxidative Stress; Resveratrol; Stilbenes | 2021 |
Piceatannol protects against cerebral ischemia/reperfusion‑induced apoptosis and oxidative stress via the Sirt1/FoxO1 signaling pathway.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Caspase 3; Forkhead Box Protein O1; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Stroke | 2020 |
Resveratrol: nanocarrier-based delivery systems to enhance its therapeutic potential.
Topics: Administration, Oral; Biological Availability; Drug Delivery Systems; Resveratrol; Solubility; Stilbenes | 2020 |
An approach of fatty acids and resveratrol in the prevention of COVID-19 severity.
Topics: COVID-19; Dietary Supplements; Fatty Acids; Humans; Resveratrol; Stilbenes | 2021 |
One-pot method based on deep eutectic solvent for extraction and conversion of polydatin to resveratrol from Polygonum cuspidatum.
Topics: Chemical Fractionation; Fallopia japonica; Glucosides; Hydrolysis; Resveratrol; Solvents; Stilbenes | 2021 |
Methoxy-stilbenes downregulate the transcription of Wnt/β-catenin-dependent genes and lead to cell cycle arrest and apoptosis in human T98G glioblastoma cells.
Topics: Antioxidants; Apoptosis; beta Catenin; Cell Cycle Checkpoints; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Resveratrol; Stilbenes; Tumor Cells, Cultured; Wnt1 Protein | 2021 |
Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol.
Topics: Antioxidants; Apoptosis; Cell Differentiation; Cell Line; Heme Oxygenase-1; Humans; Mitochondria; Myoblasts; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Stilbenes; Up-Regulation | 2021 |
Production and antimicrobial activity of trans-resveratrol, trans-arachidin-1 and trans-arachidin-3 from elicited peanut hairy root cultures in shake flasks compared with bioreactors.
Topics: Anti-Infective Agents; Arachis; Bacterial Outer Membrane Proteins; Bioreactors; Escherichia coli; Escherichia coli Proteins; Plant Roots; Resveratrol; Staphylococcus aureus; Stilbenes | 2021 |
Resveratrol supplementation at old age reverts changes associated with aging in inflammatory, oxidative and apoptotic markers in rat heart.
Topics: Aging; Animals; Antioxidants; Dietary Supplements; Male; Oxidative Stress; Rats; Resveratrol; Stilbenes | 2021 |
Resveratrol: Change of SIRT 1 and AMPK signaling pattern during the aging process.
Topics: Aged; Aging; AMP-Activated Protein Kinases; Humans; Middle Aged; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2021 |
A comparative study on the effects of resveratrol and oxyresveratrol against tyrosinase activity and their inhibitory mechanism.
Topics: Enzyme Inhibitors; Molecular Docking Simulation; Monophenol Monooxygenase; Plant Extracts; Resveratrol; Stilbenes | 2021 |
Pterostilbene and its nicotinate derivative ameliorated vascular endothelial senescence and elicited endothelium-dependent relaxations via activation of sirtuin 1.
Topics: Animals; Cells, Cultured; Cellular Senescence; Endothelial Cells; Humans; Male; Niacin; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes; Vasodilation | 2021 |
Anti-insulin resistance effect of constituents from Senna siamea on zebrafish model, its molecular docking, and structure-activity relationships.
Topics: alpha-Glucosidases; Animals; Anthraquinones; Diabetes Mellitus; Dipeptidyl Peptidase 4; Emodin; Hypoglycemic Agents; Insulin Resistance; Molecular Docking Simulation; Molecular Structure; Plant Extracts; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Resveratrol; Senna Plant; Stilbenes; Structure-Activity Relationship; Thailand; Wood; Zebrafish | 2021 |
SIRT1 attenuates sepsis-induced acute kidney injury via Beclin1 deacetylation-mediated autophagy activation.
Topics: Acetylation; Acute Kidney Injury; Animals; Autophagy; Beclin-1; Cell Line; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Glucosides; Humans; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Resveratrol; Sepsis; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors | 2021 |
Identification of regulated proteins by resveratrol in glutamate-induced cortical injury of newborn rats.
Topics: Animals; Animals, Newborn; Glutamic Acid; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Resveratrol; Rodent Diseases; Stilbenes | 2021 |
Overexpression of VlPRX21 and VlPRX35 genes in Arabidopsis plants leads to bioconversion of trans-resveratrol to δ-viniferin.
Topics: Arabidopsis; Benzofurans; Resorcinols; Resveratrol; Stilbenes; Vitis | 2021 |
Potential neuroprotective of trans-resveratrol a promising agent tempeh and soybean seed coats-derived against beta-amyloid neurotoxicity on primary culture of nerve cells induced by 2-methoxyethanol.
Topics: Amyloid beta-Peptides; Animals; Ethylene Glycols; Glycine max; Mice; Neurons; Resveratrol; Soy Foods; Stilbenes | 2021 |
Resveratrol Derivative, Trans-3, 5, 4'-Trimethoxystilbene Sensitizes Osteosarcoma Cells to Apoptosis via ROS-Induced Caspases Activation.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Osteosarcoma; Poly (ADP-Ribose) Polymerase-1; Proto-Oncogene Proteins; Reactive Oxygen Species; Resveratrol; Stilbenes; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53 | 2021 |
Pterostilbene modifies triglyceride metabolism in hepatic steatosis induced by high-fat high-fructose feeding: a comparison with its analog resveratrol.
Topics: Adipose Tissue; Animals; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Fructose; Lipids; Lipogenesis; Liver; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Triglycerides | 2021 |
Plant-Derived Stilbenoids as DNA-Binding Agents: From Monomers to Dimers.
Topics: Circular Dichroism; DNA; G-Quadruplexes; Molecular Docking Simulation; Resveratrol; Stilbenes | 2021 |
Resveratrol-zinc nanoparticles or pterostilbene-zinc: Potential COVID-19 mono and adjuvant therapy.
Topics: Antiviral Agents; COVID-19 Drug Treatment; Drug Delivery Systems; Humans; Nanoparticles; Resveratrol; Stilbenes; Zinc | 2021 |
Rational Design of Resveratrol O-methyltransferase for the Production of Pinostilbene.
Topics: Metabolic Engineering; Methyltransferases; Models, Molecular; Phylogeny; Plant Proteins; Protein Conformation; Recombinant Proteins; Resveratrol; Stilbenes; Vitis | 2021 |
Cardioprotection stimulated by resveratrol and grape products prevents lethal cardiac arrhythmias in an animal model of ischemia and reperfusion.
Topics: Animals; Arrhythmias, Cardiac; Humans; Ischemia; Male; Rats; Rats, Wistar; Reperfusion; Resveratrol; Stilbenes; Vitis | 2021 |
Resveratrol improved hippocampal neurogenesis following lead exposure in rats through activation of SIRT1 signaling.
Topics: Animals; Hippocampus; Lead; Male; Neurogenesis; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Stilbenes | 2021 |
Glucose-6-phosphate dehydrogenase inhibitor for treatment of severe COVID-19: Polydatin.
Topics: Anti-Inflammatory Agents; Antioxidants; COVID-19; COVID-19 Drug Treatment; Glucosephosphate Dehydrogenase; Glucosides; Humans; Inflammation; Lung; Magnoliopsida; Oxidative Stress; Pandemics; Phytotherapy; Plant Extracts; Resveratrol; SARS-CoV-2; Stilbenes | 2021 |
Gut Microbiota Induced by Pterostilbene and Resveratrol in High-Fat-High-Fructose Fed Rats: Putative Role in Steatohepatitis Onset.
Topics: Animals; Diet, Carbohydrate Loading; Diet, High-Fat; Dietary Fats; Fructose; Gastrointestinal Microbiome; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2021 |
Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays.
Topics: Angiotensin-Converting Enzyme 2; COVID-19; COVID-19 Drug Treatment; Drug Discovery; Drugs, Chinese Herbal; Enzyme Inhibitors; Glucosides; Host-Pathogen Interactions; Humans; Molecular Docking Simulation; Protein Binding; Resveratrol; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Stilbenes | 2021 |
Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells.
Topics: Animals; Antiviral Agents; Bronchi; Cell Line; Cells, Cultured; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Epithelial Cells; Female; Humans; Male; Middle Aged; Resveratrol; SARS-CoV-2; Stilbenes; Vero Cells; Virus Replication | 2021 |
Resveratrol: A Vital Therapeutic Agent with Multiple Health Benefits.
Topics: Antioxidants; Humans; Neoplasms; Resveratrol; Stilbenes | 2022 |
Diversity and characteristics of culturable endophytic bacteria from Passiflora edulis seeds.
Topics: Bacteria; Disease Resistance; Endophytes; Microbial Sensitivity Tests; Passiflora; Resveratrol; Seeds; Stilbenes | 2021 |
Comparison of the Effects of Resveratrol and Its Derivatives on the Radiation Response of MCF-7 Breast Cancer Cells.
Topics: Breast Neoplasms; Female; Glucosides; Humans; MCF-7 Cells; Radiation Tolerance; Radiation, Ionizing; Resveratrol; Stilbenes | 2021 |
Dietary Pterostilbene and Resveratrol Modulate the Gut Microbiota Influenced by Circadian Rhythm Dysregulation.
Topics: Animals; Circadian Rhythm; Dysbiosis; Gastrointestinal Microbiome; Mice; Resveratrol; Stilbenes | 2021 |
Co-Crystals of Resveratrol and Polydatin with L-Proline: Crystal Structures, Dissolution Properties, and In Vitro Cytotoxicities.
Topics: A549 Cells; Cell Survival; Crystallization; Drug Compounding; Glucosides; HEK293 Cells; Humans; In Vitro Techniques; Molecular Conformation; Proline; Resveratrol; Solubility; Stilbenes | 2021 |
Modifications in the Intestinal Functionality, Morphology and Microbiome Following Intra-Amniotic Administration (
Topics: Amnion; Animals; Chick Embryo; Chickens; Cytokines; Drug Synergism; Fruit; Gastrointestinal Microbiome; Gene Expression; Intestines; Microvilli; Minerals; Resveratrol; Stilbenes; Vitis | 2021 |
Piceatannol, a Structural Analog of Resveratrol, Is an Apoptosis Inducer and a Multidrug Resistance Modulator in HL-60 Human Acute Myeloid Leukemia Cells.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autophagy; Caspase 3; Cell Cycle; Cell Survival; DNA Fragmentation; Drug Resistance, Multiple; HL-60 Cells; Humans; Inhibitory Concentration 50; Leukemia, Myeloid, Acute; Membrane Potential, Mitochondrial; Molecular Structure; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2021 |
Resveratrol and its derivative pterostilbene attenuate oxidative stress-induced intestinal injury by improving mitochondrial redox homeostasis and function via SIRT1 signaling.
Topics: Animals; Apoptosis; Homeostasis; Hydrogen Peroxide; Mitochondria; Oxidation-Reduction; Oxidative Stress; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Swine | 2021 |
Development of a novel UPLC-MS/MS method for the simultaneously quantification of polydatin and resveratrol in plasma: Application to a pharmacokinetic study in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Feces; Glucosides; Male; Plasma; Rats; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2021 |
Effective inhibition of coronavirus replication by
Topics: Antiviral Agents; Cell Line, Tumor; Cell Survival; COVID-19; Drugs, Chinese Herbal; Fallopia japonica; Glucosides; HEK293 Cells; Host-Pathogen Interactions; Humans; Medicine, Chinese Traditional; Pandemics; Protein Binding; Resveratrol; SARS-CoV-2; Stilbenes; Surface Plasmon Resonance; Viral Proteins; Virus Replication | 2021 |
Combination of Trans-Resveratrol and ε-Viniferin Induces a Hepatoprotective Effect in Rats with Severe Acute Liver Failure via Reduction of Oxidative Stress and MMP-9 Expression.
Topics: Animals; Benzofurans; Disease Models, Animal; Liver; Liver Failure, Acute; Matrix Metalloproteinase 9; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Resveratrol; Stilbenes | 2021 |
Topical administration of pterostilbene accelerates burn wound healing in diabetes through activation of the HIF1α signaling pathway.
Topics: Administration, Topical; Animals; Burns; Diabetes Mellitus, Experimental; Human Umbilical Vein Endothelial Cells; Humans; Rats; Resveratrol; Signal Transduction; Stilbenes; Wound Healing | 2022 |
Antioxidant Activity and Mechanism of Resveratrol and Polydatin Isolated from Mulberry (
Topics: Antioxidants; Glucosides; Hep G2 Cells; Humans; Morus; Oxidative Stress; Resveratrol; Stilbenes | 2021 |
Computation-guided asymmetric total syntheses of resveratrol dimers.
Topics: Biological Products; Chemistry Techniques, Synthetic; Density Functional Theory; Dimerization; Drug Design; Heterocyclic Compounds, 4 or More Rings; Humans; Resveratrol; Stereoisomerism; Stilbenes | 2022 |
Molecular encapsulation and bioactivity of gnetol, a resveratrol analogue, for use in foods.
Topics: Antioxidants; Cyclodextrins; Resveratrol; Solubility; Stilbenes | 2022 |
Effect of high-dose 290 nm UV-B on resveratrol content in grape skins.
Topics: Fruit; Phenols; Resveratrol; Stilbenes; Ultraviolet Rays; Vitis | 2022 |
Conductive polymer sorbent for extraction and determination of resveratrol and polydatin in Polygonum cuspidatum root samples.
Topics: Chromatography, High Pressure Liquid; Fallopia japonica; Glucosides; Polymers; Resveratrol; Stilbenes | 2022 |
Highly Efficient Bioconversion of
Topics: Benzofurans; Culture Media, Conditioned; Hydrogen Peroxide; Peroxidase; Resorcinols; Resveratrol; Stilbenes; Vitis | 2022 |
Interactions of resveratrol and its metabolites (resveratrol-3-sulfate, resveratrol-3-glucuronide, and dihydroresveratrol) with serum albumin, cytochrome P450 enzymes, and OATP transporters.
Topics: Cytochrome P-450 Enzyme System; Glucuronides; Humans; Organic Anion Transporters; Polyphenols; Resveratrol; Serum Albumin; Serum Albumin, Human; Stilbenes | 2022 |
Identification and structural elucidation of bioactive compounds from Scirpoides holoschoenus.
Topics: Botrytis; Cyperaceae; Diterpenes; Flavonoids; Resveratrol; Stilbenes; Vitis | 2022 |
Resveratrol ameliorates muscle atrophy in chronic kidney disease via the axis of SIRT1/FoxO1.
Topics: Animals; Forkhead Box Protein O1; Mice; Muscular Atrophy; Nerve Tissue Proteins; Rats; Renal Insufficiency, Chronic; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes | 2022 |
Elucidation of the inhibitory effect of (+)-hopeaphenol on polyinosinic-polycytidylic acid-induced innate immunity activation in human cerebral microvascular endothelial cells.
Topics: Chemokine CXCL10; Endothelial Cells; Humans; Immunity, Innate; Interferon-beta; Phenols; Poly I-C; Resveratrol; Stilbenes | 2022 |
Protective effect of pterostilbene in a streptozotocin-induced mouse model of Alzheimer's disease by targeting monoamine oxidase B.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; bcl-2-Associated X Protein; Caspase 3; Disease Models, Animal; Humans; Inflammation; Interleukin-6; Mice; Mice, Inbred C57BL; Monoamine Oxidase; Neurodegenerative Diseases; NF-kappa B; Reactive Oxygen Species; Resveratrol; Stilbenes; Streptozocin; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2022 |
Pterostilbene production of tomato transformed with resveratrol synthase and resveratrol O-methyltransferase genes.
Topics: Acyltransferases; Chromatography, Liquid; Humans; Methyltransferases; Plant Breeding; Plants, Genetically Modified; Resveratrol; Solanum lycopersicum; Stilbenes; Tandem Mass Spectrometry | 2022 |
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Fibrosis; Kidney; Lipids; Mice; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2022 |
Evaluation of Resveratrol and Piceatannol Anticonvulsant Potential in Adult Zebrafish (Danio rerio).
Topics: Animals; Anticonvulsants; Caspase 3; Diazepam; Epilepsy; Interleukin-1beta; Neuroprotective Agents; Pentylenetetrazole; Resveratrol; Seizures; Stilbenes; Zebrafish | 2022 |
Microplate bioassay to examine the effects of grapevine-isolated stilbenoids on survival of root knot nematodes.
Topics: Animals; Biological Assay; Nematoda; Resveratrol; Stilbenes; Vitis | 2022 |
Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications.
Topics: Biological Availability; Fluorescent Dyes; Resveratrol; Stilbenes | 2022 |
Resveratrol as a Promising Polyphenol in Age-Associated Cardiac Alterations.
Topics: Animals; Antioxidants; Female; Glutathione; Heme Oxygenase (Decyclizing); Male; NF-kappa B; Oxidative Stress; Polyphenols; Rats; Rats, Wistar; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2022 |
4-Hydroxydibenzyl: a novel metabolite from the human gut microbiota after consuming resveratrol.
Topics: Antioxidants; Feces; Gastrointestinal Microbiome; Humans; Resveratrol; Stilbenes | 2022 |
Dimer stilbene, a resveratrol analogue exhibits synergy with antibiotics that target protein synthesis in eradicating Staphylococcus aureus infection.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Kanamycin; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Resveratrol; Staphylococcal Infections; Staphylococcus aureus; Stilbenes; Tetracyclines | 2022 |
Enhanced biological activity of liposomal methylated resveratrol analog 3'-hydroxy-3,4,5,4'-tetramethoxystilbene (DMU-214) in 3D patient-derived ovarian cancer model.
Topics: Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Female; Humans; Liposomes; Ovarian Neoplasms; Resveratrol; Stilbenes | 2022 |
Cytotoxic and Antioxidant Activities of Imine Analogs of Trans-Resveratrol towards Murine Neuronal N2a Cells.
Topics: Animals; Antineoplastic Agents; Antioxidants; Imines; Mice; Resveratrol; Stilbenes | 2022 |
Lunularin Producers versus Non-producers: Novel Human Metabotypes Associated with the Metabolism of Resveratrol by the Gut Microbiota.
Topics: Bibenzyls; Female; Gastrointestinal Microbiome; Humans; Phenols; Resveratrol; Stilbenes | 2022 |
Three Australian Lepidosperma Labill. Species as sources of prenylated and oxyprenylated derivatives of piceatannol, resveratrol and pinosylvin: Melatoninergic binding and inhibition of quinone reductase 2.
Topics: Australia; Cyperaceae; Neoprene; Quinone Reductases; Resveratrol; Stilbenes | 2022 |
Distinctive anti-inflammatory effects of resveratrol, dihydroresveratrol, and 3-(4-hydroxyphenyl)-propionic acid on DSS-induced colitis in pseudo-germ-free mice.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bibenzyls; Colitis; Dextran Sulfate; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-kappa B; Phenols; Phenylpropionates; Polyphenols; Propionates; Resveratrol; Stilbenes; Tandem Mass Spectrometry | 2023 |
Resveratrol Carbon Dots Disrupt Mitochondrial Function in Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Calcium; Carbon; Curcumin; Electron Transport Complex IV; Mitochondria; Neoplasms; Polyphenols; Resveratrol; Stilbenes | 2022 |
Differential Protective Effect of Resveratrol and Its Microbial Metabolites on Intestinal Barrier Dysfunction is Mediated by the AMPK Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Caco-2 Cells; Colitis; Humans; Intestinal Mucosa; Mice; Permeability; Resveratrol; Stilbenes; Tight Junction Proteins; Tight Junctions | 2022 |
In Vitro and in Silico Investigation of DNA Interaction, Topoisomerase I and II Inhibitory Properties of Polydatin.
Topics: DNA; DNA Topoisomerases, Type II; Glucosides; Molecular Docking Simulation; Resveratrol; Stilbenes | 2022 |
Exploring the mechanism of stilbenes to quench singlet oxygen based on the key structures of resveratrol and its analogues.
Topics: Carbon; Catechols; Resveratrol; Singlet Oxygen; Stilbenes | 2023 |
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Topics: Animals; Brain Injuries, Traumatic; Cognitive Dysfunction; Mice; Neuroprotective Agents; Peroxisome Proliferator-Activated Receptors; Resveratrol; Sirtuin 1; Stilbenes; Synaptophysin | 2022 |
Computation-Guided Total Synthesis of Vitisinol G.
Topics: Resveratrol; Stilbenes | 2022 |
Is It Possible to Improve the Bioavailability of Resveratrol and Polydatin Derived from
Topics: Antioxidants; Biological Availability; Cyclodextrins; Drugs, Chinese Herbal; Glucosides; Methanol; Nanofibers; Povidone; Resveratrol; Stilbenes | 2022 |
MYB30 and MYB14 form a repressor-activator module with WRKY8 that controls stilbene biosynthesis in grapevine.
Topics: Acyltransferases; Gene Expression Regulation, Plant; Plant Proteins; Promoter Regions, Genetic; Resveratrol; Stilbenes; Vitis | 2023 |
Resveratrol Analogues as Selective Estrogen Signaling Pathway Modulators: Structure-Activity Relationship.
Topics: Antioxidants; Estrogens; Phytoestrogens; Receptors, Estrogen; Resveratrol; Selective Estrogen Receptor Modulators; Signal Transduction; Stilbenes; Structure-Activity Relationship | 2022 |
Temperature and light conditions affect stability of phenolic compounds of stored grape cane extracts.
Topics: Canes; Phenols; Resveratrol; Stilbenes; Temperature; Vitis | 2023 |
Trans-gnetin H isolated from the seeds of Paeonia species induces autophagy via inhibiting mTORC1 signalling through AMPK activation.
Topics: AMP-Activated Protein Kinases; Autophagy; Humans; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Paeonia; Resveratrol; Seeds; Stilbenes | 2023 |
Resveratrol derivatives: Synthesis and their biological activities.
Topics: Adenocarcinoma; Antineoplastic Agents; Antioxidants; Humans; Pancreatic Neoplasms; Resveratrol; Stilbenes | 2023 |
Resveratrol ameliorates the behavioural and molecular changes in rats exposed to uninephrectomy: role of hippocampal SIRT1, BDNF and AChE.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Hippocampus; Male; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Resveratrol; Sirtuin 1; Stilbenes | 2023 |
Resveratrol-like Compounds as SIRT1 Activators.
Topics: Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes | 2022 |
Suffruticosol C-Mediated Autophagy and Cell Cycle Arrest via Inhibition of mTORC1 Signaling.
Topics: Apoptosis; Autophagy; Cell Cycle Checkpoints; Mechanistic Target of Rapamycin Complex 1; Paeonia; Resveratrol; Stilbenes | 2022 |
Preliminary investigation on impact of intergenerational treatment of resveratrol endorses the development of 'super-pups'.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Glutathione; Oxidative Stress; Rats; Resveratrol; Stilbenes | 2023 |
Nutritional epigenomic and DNA-damage modulation effect of natural stilbenoids.
Topics: Caco-2 Cells; Epigenomics; Humans; Resveratrol; Stilbenes; Vitis | 2023 |
Investigation of the Effects of Monomeric and Dimeric Stilbenoids on Bacteria-Induced Cytokines and LPS-Induced ROS Formation in Bone Marrow-Derived Dendritic Cells.
Topics: Animals; Antioxidants; Bone Marrow; Cytokines; Dendritic Cells; Escherichia coli; Interleukin-10; Interleukin-12; Lipopolysaccharides; Mice; Reactive Oxygen Species; Resveratrol; Stilbenes; Tumor Necrosis Factor-alpha | 2023 |
Transthyretin Binding Mode Dichotomy of Fluorescent
Topics: Benzene; Binding Sites; Coloring Agents; Crystallography, X-Ray; Ligands; Models, Molecular; Naphthalenes; Prealbumin; Protein Binding; Resveratrol; Stilbenes | 2023 |
Novel ferrocene-containing triacyl derivative of resveratrol improves viability parameters in ovary cells.
Topics: Antioxidants; Apoptosis; Metallocenes; Reactive Oxygen Species; Resveratrol; Stilbenes | 2023 |
Antifungal Activities of a Grapevine Byproduct Extract Enriched in Complex Stilbenes and Stilbenes Metabolization by
Topics: Antifungal Agents; Plant Extracts; Resveratrol; Stilbenes; Vitis | 2023 |
Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle.
Topics: Animals; Apoptosis; Cell Cycle; Cell Death; Mice; Mitochondria; Reactive Oxygen Species; Resveratrol; S Phase; Stilbenes | 2023 |
Studies on the Anticancer and Antioxidant Activities of Resveratrol and Long-Chain Fatty Acid Esters.
Topics: Adenocarcinoma; Antioxidants; Apoptosis; Esters; Fatty Acids; Humans; Resveratrol; Stilbenes; Superoxide Dismutase | 2023 |
Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice.
Topics: Aging; Animals; Hypertrophy; Mice; Muscle, Skeletal; Myocytes, Cardiac; Resveratrol; Sarcopenia; Sirtuin 1; Stilbenes | 2023 |
Characterization of Some Stilbenoids Extracted from Two Cultivars of Lambrusco-
Topics: Plant Extracts; Resveratrol; Stilbenes; Time; Vitis | 2023 |
Intracellular Redox Behavior of Quercetin and Resveratrol Singly and in Mixtures.
Topics: Antioxidants; HeLa Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Polyphenols; Quercetin; Reactive Oxygen Species; Resveratrol; Stilbenes | 2023 |
Use of Germination to Enhance Resveratrol Content and Its Anti-Inflammatory Activity in Lipopolysaccharide-Stimulated RAW264.7 Cells.
Topics: Animals; Anti-Inflammatory Agents; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Resveratrol; Stilbenes | 2023 |
Caulobacter segnis Dioxygenase CsO2: A Practical Biocatalyst for Stilbenoid Ozonolysis.
Topics: Dioxygenases; Ozone; Resveratrol; Stilbenes | 2023 |
An automated accelerated salting-out assisted solvent extraction (A-ASASE) of stilbenoids from Vitis vinifera L. branches: False proof or a proof of concept?
Topics: Chromatography, High Pressure Liquid; Ethanol; Liquid-Liquid Extraction; Resveratrol; Sodium Chloride; Solvents; Stilbenes; Vitis; Water | 2024 |
Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4'-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model.
Topics: Cholesterol Side-Chain Cleavage Enzyme; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Humans; Liposomes; Multienzyme Complexes; Progesterone; Resveratrol; Stilbenes | 2023 |
Improvement of the Physicochemical Limitations of Rhapontigenin, a Cytotoxic Analogue of Resveratrol against Colon Cancer.
Topics: Antineoplastic Agents; Colonic Neoplasms; Cyclodextrins; Humans; Resveratrol; Stilbenes | 2023 |
Tissue-specific stilbene accumulation is an early response to wounding/grafting as revealed by using spatial and temporal metabolomics.
Topics: Antioxidants; Plants; Resveratrol; Stilbenes; Vitis | 2023 |
Resveratrol, ε-Viniferin, and Vitisin B from Vine: Comparison of Their In Vitro Antioxidant Activities and Study of Their Interactions.
Topics: Antioxidants; Resveratrol; Stilbenes | 2023 |
Polyphenolic Compounds in Extracts from Roasted Grapevine Canes: An Investigation for a Circular Approach to Increase Sustainability in the Viticulture Sectors.
Topics: Chromatography, High Pressure Liquid; Plant Extracts; Polyphenols; Resveratrol; Stilbenes; Temperature; Vitis | 2023 |
Evaluating the antioxidant potential of resveratrol-gold nanoparticles in preventing oxidative stress in endothelium on a chip.
Topics: Antioxidants; Endothelium; Gold; Human Umbilical Vein Endothelial Cells; Humans; Hyperglycemia; Lab-On-A-Chip Devices; Metal Nanoparticles; Oxidative Stress; Resveratrol; Stilbenes | 2023 |