Page last updated: 2024-08-16

resveratrol and srt1720

resveratrol has been researched along with srt1720 in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (9.76)29.6817
2010's30 (73.17)24.3611
2020's7 (17.07)2.80

Authors

AuthorsStudies
Bemis, JE; Boss, O; Carney, DP; Choy, W; Disch, JS; Elliott, PJ; Gagne, DJ; Galonek, H; Iffland, A; Israelian, K; Jin, L; Jirousek, MR; Lambert, PD; Lavu, S; Lynch, AV; Medvedik, O; Milne, JC; Ng, PY; Nunes, JJ; Olefsky, JM; Perni, RB; Schenk, S; Sinclair, DA; Smith, JJ; Vu, CB; Westphal, CH; Xie, R; Yang, H1
Bemis, JE; Carney, DP; Disch, JS; Gagne, DJ; Jirousek, MR; Lambert, PD; Lavu, S; Lynch, AV; Milne, JC; Ng, PY; Nunes, JJ; Olefsky, JM; Perni, RB; Schenk, S; Smith, JJ; Vu, CB1
Chen, D; Chen, K; Chen, L; Chen, X; Jiang, H; Li, J; Liu, D; Liu, H; Ning, C; Wang, J; Wu, J; Yu, N; Zhang, D; Zhao, F1
Altucci, L; Atlante, S; Budriesi, R; Carafa, V; Carnevale, I; Cencioni, C; Del Bufalo, D; Gabellini, C; Gaetano, C; Mai, A; Mellini, P; Moniot, S; Nebbioso, A; Polletta, L; Saladini, S; Spallotta, F; Steegborn, C; Tafani, M; Tardugno, M; Trisciuoglio, D; Valente, S; Zwergel, C1
Tan, Z; Teng, M; Young, DW1
Chen, D; Cole, P; Dentin, R; Guarente, L; Hedrick, S; Liu, Y; Meyers, DJ; Milne, J; Montminy, M; Olefsky, J; Ravnskjaer, K; Schenk, S; Yates, J1
Boss, O; Carney, DP; Elliott, PJ; Elliston, KO; Frushour, BP; Gagne, DJ; Galonek, HL; Iffland, A; Israelian, K; Jirousek, MR; Johnson, RJ; Kenney, RD; Ladd, W; Lambert, PD; Lavu, S; Lynch, AV; Milne, JC; Razvadauskaite, G; Smith, JJ; Song, J1
Baur, JA1
Ahn, K; Bleasdale, JE; Chrunyk, B; Cunningham, D; Flynn, D; Garofalo, RS; Griffith, D; Griffor, M; Loulakis, P; Pabst, B; Pacholec, M; Qiu, X; Stockman, B; Thanabal, V; Varghese, A; Ward, J; Withka, J1
Barker, G; Lappas, M; Lim, R; Mitton, A; Permezel, M; Riley, C1
Birringer, M; Falk, E; Ristow, M; Schmeisser, S; Schmoll, D; Zarse, K1
Alcain, FJ; de Cabo, R; Villalba, JM1
Baur, JA; de Cabo, R; Le Couteur, DG; Minor, RK; Ungvari, Z1
Hayashi, R; Ichikawa, T; Imanishi, S; Inomata, M; Kambara, K; Koshimizu, Y; Matsui, S; Matsuya, Y; Miwa, T; Okazawa, S; Sasahara, M; Suzuki, K; Tobe, K; Urakaze, M; Usui, I; Yamada, T; Yamazaki, Y1
Chong, ZZ; Maiese, K; Shang, YC; Wang, S1
Freiwald, A; Han, CT; Holzhauser, S; Multhaup, G; Sauer, S; Weise, C1
Cao, L; Liu, C; Wang, F; Wang, H1
Kondo, A; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Mizutani, J; Otsuka, T; Tokuda, H1
Chen, J; Cui, Z; Evans, LP; Hatton, CJ; Hurst, CG; Ju, M; Juan, AM; Michan, S; Pei, DT; Sinclair, DA; Smith, LE1
Kondo, A; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Mizutani, J; Otsuka, T; Tokuda, H; Yamamoto, N1
Doser, TA; Ge, J; Hu, N; Mi, SL; Ren, J; Sun, A; Zhang, Y1
Krainc, D; Xiang, Z1
Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Mizutani, J; Nakakami, A; Otsuka, T; Tokuda, H; Yamamoto, N1
Beart, PM; Klugmann, M; Lau, CL; Rae, CD; Rowlands, BD; Ryall, JG; Thomas, DS1
Albert, V; Cardel, B; Handschin, C; Quagliata, L; Schnyder, S; Svensson, K; Terracciano, LM1
Beck, JF; Becker, S; Blümel, L; Blumrich, A; Kahl, M; Krämer, OH; Siranjeevi, PM; Sonnemann, J; Winkler, R; Wittig, S1
Cao, F; Chen, Y; Han, D; Ma, S; Wang, J1
Garg, NJ; Koo, SJ; Liang, LY; Wan, X; Wen, JJ1
Ibdah, JA; Nassir, F1
Cao, W; Fan, Y; Fang, K; Jia, X; Liu, L; Liu, T; Song, Y; Sun, X; Tu, Y; Wan, L; Wang, Y; Xiang, C; Yu, D; Yu, L1
Fujita, K; Kainuma, S; Kawabata, T; Kozawa, O; Matsushima-Nishiwaki, R; Otsuka, T; Sakai, G; Tokuda, H1
Akter, J; An, HJ; Chun, P; Chung, HY; Jeong, HO; Kim, DH; Kim, MJ; Kim, SJ; Lee, B; Lee, EK; Lee, HJ; Moon, HR; Moon, KM; Ullah, S; Yang, J1
Granchi, C; Minutolo, F1
Chen, Y; Chu, L; Guo, S; He, J; Liu, J; Liu, Z; Song, Z; Xu, X; Zhang, A; Zhang, J1
Hodge, G; Hodge, S; Holmes, M; Holmes-Liew, CL; Liu, H; Nguyen, P1
Guo, J; Li, Z; Xu, Y; Yang, Y1
Bozok Cetintas, V; Duzgun, Z; Erdem, C; Eroglu, Z; Oktem, G1
Brieño-Enríquez, MA; Brooks, KE; Diao, RY; Francisco, AB; Libert, S; Nacmias, B; Nicholatos, JW; Ricca, V; Robinette, TM; Sorbi, S1
Mani, BK; Metzger, N; Osborne-Lawrence, S; Zigman, JM1
Du, L; He, LL; Li, CC; Li, XZ; Li, Y; Liu, YQ; Lu, Q; Ma, P; Qian, X; Shu, FL; Xu, L; Yin, XX1
Dong, W; Lei, X; Wang, F; Zhu, X1

Reviews

7 review(s) available for resveratrol and srt1720

ArticleYear
The Pursuit of Enzyme Activation: A Snapshot of the Gold Rush.
    Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

    Topics: Enzyme Activation; Gold; Humans; Phosphoric Monoester Hydrolases; Signal Transduction

2022
Biochemical effects of SIRT1 activators.
    Biochimica et biophysica acta, 2010, Volume: 1804, Issue:8

    Topics: Animals; Cardiotonic Agents; Energy Metabolism; Enzyme Activation; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin Resistance; Learning; Longevity; Memory; Mice; Models, Biological; NAD; Neoplasms; Niacinamide; O-Acetyl-ADP-Ribose; Resveratrol; Silent Information Regulator Proteins, Saccharomyces cerevisiae; Sirtuin 1; Stilbenes

2010
A patent review of sirtuin activators: an update.
    Expert opinion on therapeutic patents, 2012, Volume: 22, Issue:4

    Topics: Animals; Anti-Obesity Agents; Dietary Supplements; Drug Design; Enzyme Activation; Enzyme Activators; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Patents as Topic; Resveratrol; Sirtuin 1; Stilbenes; Structure-Activity Relationship

2012
Are sirtuins viable targets for improving healthspan and lifespan?
    Nature reviews. Drug discovery, 2012, Jun-01, Volume: 11, Issue:6

    Topics: Aging; Animals; Biotransformation; Caloric Restriction; Geriatrics; Health; Heterocyclic Compounds, 4 or More Rings; Humans; Life Expectancy; Mammals; Resveratrol; Sirtuin 1; Sirtuin 3; Sirtuins; Stilbenes

2012
SIRT1 as a Promising Novel Therapeutic Target for Myocardial Ischemia Reperfusion Injury and Cardiometabolic Disease.
    Current drug targets, 2017, Volume: 18, Issue:15

    Topics: Animals; Apoptosis; Disease Models, Animal; Heterocyclic Compounds, 4 or More Rings; Humans; Metabolic Diseases; Molecular Targeted Therapy; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Resveratrol; Sirtuin 1; Stilbenes; Transcriptional Activation

2017
Sirtuins and nonalcoholic fatty liver disease.
    World journal of gastroenterology, 2016, Dec-14, Volume: 22, Issue:46

    Topics: Animals; Down-Regulation; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Non-alcoholic Fatty Liver Disease; Resveratrol; Sirtuins; Stilbenes

2016
Activators of Sirtuin-1 and their Involvement in Cardioprotection.
    Current medicinal chemistry, 2018, Volume: 25, Issue:34

    Topics: Benzimidazoles; Cardiotonic Agents; Cardiovascular Diseases; Cyclooctanes; Ginsenosides; Heterocyclic Compounds, 4 or More Rings; Humans; Lignans; Polycyclic Compounds; Resveratrol; Sirtuin 1

2018

Other Studies

34 other study(ies) available for resveratrol and srt1720

ArticleYear
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
    Nature, 2007, Nov-29, Volume: 450, Issue:7170

    Topics: Acetylation; Allosteric Site; Animals; Blood Glucose; Caloric Restriction; Catalytic Domain; Cell Line; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Drosophila melanogaster; Heterocyclic Compounds, 4 or More Rings; Humans; Insulin; Male; Mice; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Zucker; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes

2007
Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.
    Journal of medicinal chemistry, 2009, Mar-12, Volume: 52, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Enzyme Activators; Hypoglycemic Agents; Imidazoles; Mice; Quinoxalines; Rats; Rats, Zucker; Sirtuin 1; Structure-Activity Relationship; Thiazoles

2009
Discovery and mechanism study of SIRT1 activators that promote the deacetylation of fluorophore-labeled substrate.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Acetylation; Fluorescent Dyes; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Sirtuin 1; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2013
1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells.
    Journal of medicinal chemistry, 2016, Feb-25, Volume: 59, Issue:4

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Dihydropyridines; Enzyme Activation; Humans; Male; Mice; Mitochondria; Neoplasms; Signal Transduction; Sirtuin 1; Skin; Wound Healing

2016
A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.
    Nature, 2008, Nov-13, Volume: 456, Issue:7219

    Topics: Acetylation; Animals; Cell Line, Transformed; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Fasting; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gluconeogenesis; Heterocyclic Compounds, 4 or More Rings; Humans; Liver; Male; Mice; Mice, Knockout; Nuclear Proteins; p300-CBP Transcription Factors; Resveratrol; Sirtuin 1; Sirtuins; Stilbenes; Trans-Activators; Transcription Factors; Ubiquitin-Protein Ligases

2008
Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.
    BMC systems biology, 2009, Mar-10, Volume: 3

    Topics: Animals; Caloric Restriction; Enzyme Activation; Gene Expression Profiling; Heterocyclic Compounds, 4 or More Rings; Mice; Microarray Analysis; Models, Genetic; Molecular Structure; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Stilbenes

2009
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.
    The Journal of biological chemistry, 2010, Mar-12, Volume: 285, Issue:11

    Topics: Acetylation; Allosteric Regulation; Animals; Blood Glucose; Calorimetry; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Activation; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mice, Obese; Nuclear Magnetic Resonance, Biomolecular; Resveratrol; Rhodamines; Sirtuin 1; Stilbenes; Substrate Specificity; Surface Plasmon Resonance; Tumor Suppressor Protein p53

2010
SIRT1 is a novel regulator of key pathways of human labor.
    Biology of reproduction, 2011, Volume: 84, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Extraembryonic Membranes; Female; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Humans; Labor, Obstetric; Placenta; Pregnancy; Prostaglandins; Resveratrol; RNA; Sirtuin 1; Sirtuin 2; Stilbenes

2011
Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2010, Volume: 42, Issue:12

    Topics: Animals; Caenorhabditis elegans; Heterocyclic Compounds, 4 or More Rings; Life Expectancy; Longevity; Resveratrol; Stilbenes

2010
Sirtuin 1 activator SRT1720 suppresses inflammation in an ovalbumin-induced mouse model of asthma.
    Respirology (Carlton, Vic.), 2013, Volume: 18, Issue:2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cytokines; Disease Models, Animal; Female; Heterocyclic Compounds, 4 or More Rings; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Pneumonia; Respiratory System; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes

2013
WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1.
    Current neurovascular research, 2013, Volume: 10, Issue:1

    Topics: Androstadienes; Caspase 3; CCN Intercellular Signaling Proteins; Cell Hypoxia; Cell Survival; Chromones; Enzyme Inhibitors; Forkhead Box Protein O3; Forkhead Transcription Factors; Heterocyclic Compounds, 4 or More Rings; Hippocampus; Homeostasis; Humans; Morpholines; Neurons; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Wortmannin

2013
Discovery and characterization of protein-modifying natural products by MALDI mass spectrometry reveal potent SIRT1 and p300 inhibitors.
    Angewandte Chemie (International ed. in English), 2013, May-03, Volume: 52, Issue:19

    Topics: Acetylation; Biological Products; Cells, Cultured; E1A-Associated p300 Protein; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Molecular Structure; Monocytes; Optical Imaging; Peptide Fragments; Resveratrol; Sirtuin 1; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stilbenes

2013
SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2013, Volume: 46, Issue:8

    Topics: Adult; Amyloid beta-Peptides; Antioxidants; Blood-Retinal Barrier; Cell Survival; Enzyme Assays; Gene Silencing; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Interleukin-6; Interleukin-8; Macular Degeneration; Matrix Metalloproteinase 9; NF-kappa B; Primary Cell Culture; Real-Time Polymerase Chain Reaction; Resveratrol; Retinal Pigment Epithelium; RNA Interference; Signal Transduction; Sirtuin 1; Stilbenes

2013
Resveratrol suppresses prostaglandin F(2α)-induced osteoprotegerin synthesis in osteoblasts: inhibition of the MAP kinase signaling.
    Archives of biochemistry and biophysics, 2014, Jan-15, Volume: 542

    Topics: 3T3 Cells; Animals; Dinoprost; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Osteoprotegerin; Phosphorylation; Protein Kinase Inhibitors; Resveratrol; RNA, Messenger; Stilbenes

2014
Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Crosses, Genetic; Disease Models, Animal; Endothelial Cells; Gene Expression; Heterocyclic Compounds, 4 or More Rings; Humans; Integrases; Macrophages; Mice; Neovascularization, Pathologic; Nerve Degeneration; Nestin; Neurons; Oxygen; Receptor, TIE-2; Resveratrol; Retina; Retinal Degeneration; Sirtuin 1; Stilbenes

2014
Resveratrol inhibits BMP-4-stimulated VEGF synthesis in osteoblasts: suppression of S6 kinase.
    International journal of molecular medicine, 2014, Volume: 33, Issue:4

    Topics: Animals; Bone Morphogenetic Protein 4; Cell Line; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Mice; Osteoblasts; Phosphorylation; Resveratrol; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Smad Proteins; Stilbenes; Vascular Endothelial Growth Factor A

2014
Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
    Free radical biology & medicine, 2014, Volume: 71

    Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; AMP-Activated Protein Kinases; Animals; Apoptosis; Atrial Remodeling; Benzamides; Benzodioxoles; Calcium; Cardiomegaly; Fibrosis; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Ion Channels; Mice; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocardial Contraction; Myocardium; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxides; Transcription Factors; Uncoupling Protein 2

2014
Pharmacological upregulation of PGC1α in oligodendrocytes: implications for Huntington's Disease.
    Journal of Huntington's disease, 2013, Volume: 2, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; Heterocyclic Compounds, 4 or More Rings; Huntington Disease; Mice; Mutation; Oligodendroglia; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Serotonin Plasma Membrane Transport Proteins; Sirtuin 1; Stilbenes; Transcription Factors; Up-Regulation

2013
Down-regulation by resveratrol of basic fibroblast growth factor-stimulated osteoprotegerin synthesis through suppression of Akt in osteoblasts.
    International journal of molecular sciences, 2014, Oct-06, Volume: 15, Issue:10

    Topics: 3T3 Cells; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Fibroblast Growth Factor 2; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Proteins; Resveratrol; Stilbenes

2014
Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism.
    Journal of neuroscience research, 2015, Volume: 93, Issue:7

    Topics: Animals; Antioxidants; Area Under Curve; Astrocytes; Brain; Carbazoles; Carbon Isotopes; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heterocyclic Compounds, 4 or More Rings; Lactic Acid; Magnetic Resonance Imaging; Male; Mitochondria; Oxidative Stress; Oxygen Consumption; Resveratrol; Sirtuin 1; Stilbenes

2015
Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α).
    The Journal of biological chemistry, 2015, Jun-26, Volume: 290, Issue:26

    Topics: Adipose Tissue; Animals; Energy Metabolism; Female; Glucose; Heterocyclic Compounds, 4 or More Rings; Lipid Metabolism; Liver; Male; Mice; Mice, Knockout; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Stilbenes; Transcription Factors

2015
Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing's sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity.
    Journal of cancer research and clinical oncology, 2016, Volume: 142, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Caspases; Cell Proliferation; Etoposide; Flow Cytometry; Heterocyclic Compounds, 4 or More Rings; Humans; Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoma, Ewing; Sirtuin 1; Stilbenes; Tumor Cells, Cultured; Vincristine

2016
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.
    PLoS pathogens, 2016, Volume: 12, Issue:10

    Topics: Animals; Antioxidants; Blotting, Western; Chagas Cardiomyopathy; Disease Models, Animal; Heart; Heterocyclic Compounds, 4 or More Rings; Humans; Inflammation; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Transcriptome; Trypanosoma cruzi

2016
Resveratrol Protects Against Pulmonary Arterial Hypertension in Rats via Activation of Silent Information Regulator 1.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 42, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blood Pressure; Cell Hypoxia; Cell Movement; Cell Proliferation; Cells, Cultured; Down-Regulation; Heterocyclic Compounds, 4 or More Rings; Hypertension, Pulmonary; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Wistar; Resveratrol; Sirtuin 1; Stilbenes; Vascular Remodeling

2017
Resveratrol Inhibits the Epidermal Growth Factor-Induced Migration of Osteoblasts: the Suppression of SAPK/JNK and Akt.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:3

    Topics: Animals; Anthracenes; Cell Movement; Cells, Cultured; Epidermal Growth Factor; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; rho-Associated Kinases; Sirtuin 1; Stilbenes

2017
Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice.
    Bioorganic & medicinal chemistry letters, 2018, 02-15, Volume: 28, Issue:4

    Topics: Acetyl-CoA Carboxylase; Animals; Benzoxazoles; Body Weight; Diabetes Mellitus; Enzyme Activators; Fatty Acid Synthases; Fatty Liver; Gene Expression Regulation; Glucose Intolerance; Heterocyclic Compounds, 4 or More Rings; Hypoglycemic Agents; Male; Metabolic Syndrome; Mice, Inbred C57BL; Molecular Docking Simulation; Resveratrol; Sirtuin 1; Sterol Regulatory Element Binding Proteins; Stilbenes

2018
The resistant effect of SIRT1 in oxidative stress-induced senescence of rat nucleus pulposus cell is regulated by Akt-FoxO1 pathway.
    Bioscience reports, 2019, 05-31, Volume: 39, Issue:5

    Topics: Animals; Antioxidants; Cell Cycle; Cellular Senescence; Chondrocytes; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Hydrogen Peroxide; Nerve Tissue Proteins; Nucleus Pulposus; Oxidative Stress; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Quinolones; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Sirtuin 1

2019
BOS Is Associated With Decreased SIRT1 in Peripheral Blood Proinflammatory T, NK, and NKT-like Lymphocytes.
    Transplantation, 2019, Volume: 103, Issue:11

    Topics: Adult; Age Factors; Bronchiolitis Obliterans; Carbazoles; Case-Control Studies; Curcumin; Cytokines; Female; Graft Survival; Heterocyclic Compounds, 4 or More Rings; Humans; Immunosuppressive Agents; Inflammation; Interferon-gamma; Killer Cells, Natural; Lung Transplantation; Lymphocytes; Male; Middle Aged; Postoperative Complications; Prednisolone; Resveratrol; Sirtuin 1; T-Lymphocytes; Theophylline; Treatment Outcome

2019
Deacetylation of MRTF-A by SIRT1 defies senescence induced down-regulation of collagen type I in fibroblast cells.
    Biochimica et biophysica acta. Molecular basis of disease, 2020, 05-01, Volume: 1866, Issue:5

    Topics: Acetylation; Animals; Benzamides; Carbazoles; Cellular Senescence; Collagen Type I; Down-Regulation; Embryo, Mammalian; Fibroblasts; HEK293 Cells; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Mutation; Naphthols; Primary Cell Culture; Promoter Regions, Genetic; Resveratrol; RNA, Small Interfering; Sirtuin 1; Trans-Activators

2020
Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells.
    Molecular medicine reports, 2020, Volume: 22, Issue:1

    Topics: A549 Cells; AC133 Antigen; Antineoplastic Agents; Apoptosis; Benzamides; Carcinoma, Non-Small-Cell Lung; Heterocyclic Compounds, 4 or More Rings; Humans; Hyaluronan Receptors; Lung Neoplasms; Naphthols; Neoplastic Stem Cells; Resveratrol; Sirtuin 1

2020
SIRT1 accelerates the progression of activity-based anorexia.
    Nature communications, 2020, 06-04, Volume: 11, Issue:1

    Topics: Animals; Anorexia Nervosa; Body Weight; Carbazoles; Disease Models, Animal; Female; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Nuclear Respiratory Factor 1; Phenotype; Receptors, N-Methyl-D-Aspartate; Resveratrol; Sirtuin 1; Stress, Mechanical; Up-Regulation

2020
Lowering oxidative stress in ghrelin cells stimulates ghrelin secretion.
    American journal of physiology. Endocrinology and metabolism, 2020, 08-01, Volume: 319, Issue:2

    Topics: Animals; Antioxidants; Cells, Cultured; Curcumin; Gastric Mucosa; Ghrelin; Glucose; Heterocyclic Compounds, 4 or More Rings; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Resveratrol

2020
Sirt1 inhibits renal tubular cell epithelial-mesenchymal transition through YY1 deacetylation in diabetic nephropathy.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:2

    Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockdown Techniques; Glucose; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Resveratrol; Sirtuin 1; YY1 Transcription Factor

2021
Resveratrol alleviates alveolar epithelial cell injury induced by hyperoxia by reducing apoptosis and mitochondrial dysfunction.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:5

    Topics: Acetylation; Alveolar Epithelial Cells; Apoptosis; Carbazoles; Cell Death; Cell Line; Cell Survival; DNA-Binding Proteins; Down-Regulation; Heterocyclic Compounds, 4 or More Rings; Humans; Hyperoxia; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Models, Biological; Nuclear Respiratory Factor 1; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Reactive Oxygen Species; Resveratrol; Sirtuin 1; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation

2021