Page last updated: 2024-08-16

resveratrol and resveratrol-4'-o-glucuronide

resveratrol has been researched along with resveratrol-4'-o-glucuronide in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.70)29.6817
2010's19 (82.61)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Canney, DJ; Iwuchukwu, OF; Nagar, S; Sharan, S; Zimmerman, CL1
Adsool, VA; Cui, YT; Goh, YL; Pendharkar, V1
Andrés-Bilbao, M; Belmonte-Reche, E; Cebrián, R; de Paz, MV; Kuipers, OP; Li, Q; Lucas, R; Morales, JC; Peñalver, P1
Davis, C; Heredia, A; Redfield, R; Song, H; Wang, LX; Yu, B; Zhang, Z1
Andres-Lacueva, C; Covas, MI; Jaeger, W; Jáuregui, O; Lamuela-Raventós, RM; Miksits, M; Urpí-Sardà, M1
Mikulski, D; Molski, M1
Booth, TD; Brenner, DE; Brown, K; Brown, VA; Crowell, JA; Gescher, AJ; Patel, KR; Perloff, M; Piccirilli, G; Schinas, AM; Sen, A; Steward, WP; Vasilinin, G; Viskaduraki, M1
Böhmdorfer, M; Jaeger, W; Maier-Salamon, A; Szekeres, T; Thalhammer, T1
Canney, DJ; Iwuchukwu, OF; Nagar, S; Sharan, S1
Andrés-Lacueva, C; Churruca, I; Eseberri, I; Lasa, A; Portillo, MP1
Aires, V; Cotte, AK; Delmas, D; Ghiringhelli, F; Latruffe, N; Limagne, E1
Carew, MA; Carrington, S; Meira, LB; Modjtahedi, H; Polycarpou, E; Tyrrell, E1
Churruca, I; Eseberri, I; Lasa, A; Portillo, MP1
Bocchi, L; Bresciani, L; Brighenti, F; Calani, L; Del Rio, D; Delucchi, F; Ray, S; Savi, M; Stilli, D1
Böhmdorfer, M; Brenner, S; Giessrigl, B; Jäger, W; Pignitter, M; Riha, J; Schueller, K; Somoza, V; Stieger, B; Szekeres, T; Thalhammer, T1
Storms, DH; Zunino, SJ1
Del Favero, G; Groh, IA; Marko, D; Pignitter, M; Schroeter, A; Schueller, K; Somoza, V1
Gao, S; Ge, S; Hu, M; Xu, B; Yin, T1
Dongari, N; Kubátová, A; Kusler, K; Leadbetter, M; Liyanage, D; Novikov, A; Rousova, J; Sauter, ER; Zhang, KK1
Baron, S; Beaudeux, JL; Bédarida, T; Cottart, CH; Dargère, D; Diestra, R; Laprévote, O; Menet, MC; Nivet-Antoine, V; Taghi, M1
Huang, S; Hwang, DH; Storms, DH; Zunino, SJ1
Böhmdorfer, M; Brenner, S; Jäger, W; Riha, J; Schiestl, RH; Szakmary, A; Szekeres, T; Thalhammer, T; Vaquero, J1
Ames-Sibin, AP; Bersani-Amado, CA; Bracht, A; Bracht, L; Comar, JF; Lima, EP; Mathias, PCF; Pateis, VO; Peralta, RM; Sá-Nakanishi, AB; Simões, MS1

Reviews

1 review(s) available for resveratrol and resveratrol-4'-o-glucuronide

ArticleYear
Chemically Tuning Resveratrol for the Effective Killing of Gram-Positive Pathogens.
    Journal of natural products, 2022, 06-24, Volume: 85, Issue:6

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Resveratrol

2022

Trials

1 trial(s) available for resveratrol and resveratrol-4'-o-glucuronide

ArticleYear
Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis.
    Cancer research, 2010, Nov-15, Volume: 70, Issue:22

    Topics: Abdominal Pain; Adult; Antineoplastic Agents, Phytogenic; Area Under Curve; Chromatography, High Pressure Liquid; Diarrhea; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glucuronides; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Metabolic Clearance Rate; Middle Aged; Nausea; Resveratrol; Stilbenes; Young Adult

2010

Other Studies

21 other study(ies) available for resveratrol and resveratrol-4'-o-glucuronide

ArticleYear
In vivo-formed versus preformed metabolite kinetics of trans-resveratrol-3-sulfate and trans-resveratrol-3-glucuronide.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:10

    Topics: Animals; Area Under Curve; Biotransformation; Glucuronides; Half-Life; Injections, Intra-Arterial; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Models, Biological; Resveratrol; Stilbenes; Sulfates

2012
Toward Resolving the Resveratrol Conundrum: Synthesis and
    ACS medicinal chemistry letters, 2017, May-11, Volume: 8, Issue:5

    Topics:

2017
Resveratrol glucuronides as the metabolites of resveratrol in humans: characterization, synthesis, and anti-HIV activity.
    Journal of pharmaceutical sciences, 2004, Volume: 93, Issue:10

    Topics: Administration, Oral; Anti-HIV Agents; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Didanosine; Dose-Response Relationship, Drug; Drug Synergism; Glucuronides; HIV Infections; Humans; Hydrolysis; Leukocytes, Mononuclear; Resveratrol; Stilbenes; Structure-Activity Relationship; Time Factors

2004
Uptake of diet resveratrol into the human low-density lipoprotein. Identification and quantification of resveratrol metabolites by liquid chromatography coupled with tandem mass spectrometry.
    Analytical chemistry, 2005, May-15, Volume: 77, Issue:10

    Topics: Antioxidants; Calibration; Chromatography, Liquid; Diet; Glucosides; Glucuronides; Humans; Lipoproteins, LDL; Reproducibility of Results; Resveratrol; Sensitivity and Specificity; Stilbenes; Tandem Mass Spectrometry

2005
Quantitative structure-antioxidant activity relationship of trans-resveratrol oligomers, trans-4,4'-dihydroxystilbene dimer, trans-resveratrol-3-O-glucuronide, glucosides: trans-piceid, cis-piceid, trans-astringin and trans-resveratrol-4'-O-beta-D-glucopy
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: Dimerization; Free Radical Scavengers; Glucose; Glucosides; Glucuronides; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Quantum Theory; Resveratrol; Stereoisomerism; Stilbenes

2010
Hepatic glucuronidation of resveratrol: interspecies comparison of enzyme kinetic profiles in human, mouse, rat, and dog.
    Drug metabolism and pharmacokinetics, 2011, Volume: 26, Issue:4

    Topics: Animals; Dogs; Enzyme Inhibitors; Glucuronides; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Liver; Male; Mice; Microsomes, Liver; Models, Animal; Models, Theoretical; Rats; Rats, Wistar; Resveratrol; Species Specificity; Stilbenes

2011
Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies.
    Journal of pharmaceutical and biomedical analysis, 2012, Apr-07, Volume: 63

    Topics: Animals; Biological Availability; Biotransformation; Chromatography, Liquid; Glucuronides; Injections, Intra-Arterial; Male; Mice; Mice, Inbred C57BL; Models, Animal; Reference Standards; Reproducibility of Results; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes; Sulfates; Tandem Mass Spectrometry

2012
Delipidating effect of resveratrol metabolites in 3T3-L1 adipocytes.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Fatty Acid Synthases; Gene Expression Regulation; Glucuronides; Lipoprotein Lipase; Mice; PPAR gamma; Real-Time Polymerase Chain Reaction; Resveratrol; RNA, Messenger; Stilbenes; Triglycerides

2012
Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Synergism; Glucuronides; Humans; Resveratrol; Stilbenes

2013
Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:10

    Topics: Adenosine A3 Receptor Antagonists; AMP-Activated Protein Kinases; Apoptosis; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cyclin D1; G1 Phase Cell Cycle Checkpoints; Glucuronides; Hemolysis; Humans; Receptor, Adenosine A3; Resveratrol; Stilbenes

2013
Resveratrol metabolites modify adipokine expression and secretion in 3T3-L1 pre-adipocytes and mature adipocytes.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Adiponectin; Animals; Apelin; Cell Differentiation; Gene Expression; Glucuronides; Intercellular Signaling Peptides and Proteins; Leptin; Mice; Nicotinamide Phosphoribosyltransferase; Resveratrol; RNA, Messenger; Stilbenes

2013
Bioaccumulation of resveratrol metabolites in myocardial tissue is dose-time dependent and related to cardiac hemodynamics in diabetic rats.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2014, Volume: 24, Issue:4

    Topics: Animals; Biotransformation; Blood Glucose; Body Weight; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Glucuronides; Heart Diseases; Hemodynamics; Male; Myocardium; Rats, Wistar; Resveratrol; Stilbenes; Sulfates; Time Factors

2014
Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:9

    Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; CHO Cells; Cricetulus; Female; Gene Knockdown Techniques; Glucuronides; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Resveratrol; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Stilbenes

2014
Physiological levels of resveratrol metabolites are ineffective as anti-leukemia agents against Jurkat leukemia cells.
    Nutrition and cancer, 2015, Volume: 67, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Death; Cell Proliferation; Glucuronides; Humans; Jurkat Cells; Membrane Potential, Mitochondrial; Mitochondrial Membranes; Resveratrol; Stilbenes

2015
Inhibition of topoisomerase II by phase II metabolites of resveratrol in human colon cancer cells.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:12

    Topics: Apoptosis; Caco-2 Cells; Cell-Free System; Colonic Neoplasms; Comet Assay; Drug Screening Assays, Antitumor; Glucuronides; HT29 Cells; Humans; Resveratrol; Stilbenes; Topoisomerase II Inhibitors

2015
Curcumin Affects Phase II Disposition of Resveratrol Through Inhibiting Efflux Transporters MRP2 and BCRP.
    Pharmaceutical research, 2016, Volume: 33, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Line, Transformed; Curcumin; Dogs; Glucuronides; Glucuronosyltransferase; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Male; Membrane Transport Proteins; Metabolic Detoxication, Phase II; Mice; Mice, Knockout; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Resveratrol; Stilbenes; UDP-Glucuronosyltransferase 1A9

2016
Determination of trans-resveratrol and its metabolites in rat serum using liquid chromatography with high-resolution time of flight mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016, Dec-15, Volume: 1039

    Topics: Animals; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Chromatography, High Pressure Liquid; Deuterium Exchange Measurement; Female; Glucuronides; Limit of Detection; Rats; Resveratrol; Spectrometry, Mass, Electrospray Ionization; Stilbenes

2016
Distribution of trans-resveratrol and its metabolites after acute or sustained administration in mouse heart, brain, and liver.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:8

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Glucuronides; Heart; Liver; Mass Spectrometry; Mice; Resveratrol; Stilbenes; Tissue Distribution

2017
Resveratrol increases phagocytosis and lipopolysaccharide-induced interleukin-1β production, but decreases surface expression of Toll-like receptor 2 in THP-1 monocytes.
    Cytokine, 2018, Volume: 102

    Topics: Cell Death; Glucuronides; Humans; Interleukin-1beta; Lipopolysaccharides; Monocytes; Phagocytosis; Phytochemicals; Resveratrol; Stilbenes; THP-1 Cells; Toll-Like Receptor 2; Toll-Like Receptor 4

2018
Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice.
    Nutrients, 2017, Dec-12, Volume: 9, Issue:12

    Topics: Animals; Glucuronides; Glucuronosyltransferase; Mice; Resveratrol; Stilbenes; Sulfotransferases; Tissue Distribution

2017
Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats.
    Life sciences, 2022, Dec-01, Volume: 310

    Topics: Animals; Biotransformation; Gluconeogenesis; Glycogen; Liver; Rats; Resveratrol

2022