Compounds > resiquimod
Page last updated: 2024-09-04

resiquimod and cl 075

resiquimod has been researched along with cl 075 in 8 studies

Compound Research Comparison

Studies
(resiquimod)		Trials
(resiquimod)		Recent Studies (post-2010)
(resiquimod)		Studies
(cl 075)		Trials
(cl 075)		Recent Studies (post-2010) (cl 075)
4651431828023

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's7 (87.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horscroft, N; Laxton, C; Myangar, N; Parkinson, T; Rodman, J; Thomas, A1
Bigalke, I; Bürdek, M; Frankenberger, B; Geiger, C; Javorovic, M; Mosetter, B; Schendel, DJ; Spranger, S; Tippmer, S; Wilde, S1
Du, J; Gao, M; Qu, C; Randolph, GJ; Ren, S; Wei, Y; Wu, Z1
Dietsch, GN; Dowling, DJ; Hershberg, RM; Levy, O; Matthews, MA; Palmer, CD; Prokopowicz, ZM; Tan, Z1
Miyake, K; Ohto, U; Shibata, T; Shimizu, T; Tanji, H1
Briercheck, E; Butchar, JP; Byrd, JC; Caligiuri, M; Cheney, C; Dietsch, GN; Elavazhagan, S; Fang, H; Fatehchand, K; Gautam, S; Hershberg, RM; Mo, X; Reader, B; Ren, L; Santhanam, V; Tridandapani, S; Vasilakos, JP1
Chai, HH; Cho, YM; Choi, BH; Lim, D; Suk, JE1
Affandi, AJ; Boes, M; Cossu, M; Radstake, TRDJ; Silva-Cardoso, SC; Spel, L; van Roon, JAG1

Other Studies

8 other study(ies) available for resiquimod and cl 075

ArticleYear
Investigating Toll-like receptor agonists for potential to treat hepatitis C virus infection.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Antiviral Agents; Cell Line, Tumor; Cytokines; Hepacivirus; Hepatitis C; Humans; Leukocytes, Mononuclear; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 9; Toll-Like Receptors

2007
Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075.
    Journal of immunology (Baltimore, Md. : 1950), 2010, Jul-01, Volume: 185, Issue:1

    Topics: Adjuvants, Immunologic; Cancer Vaccines; Cell Differentiation; Cell Movement; Cell Polarity; Cells, Cultured; Coculture Techniques; Cytokines; Dendritic Cells; Humans; Imidazoles; Immunotherapy, Adoptive; Interferon-gamma; Killer Cells, Natural; Ligands; Lymphocyte Activation; Poly I-C; Quinolines; T-Lymphocytes, Cytotoxic; Th1 Cells; Thiazoles; Toll-Like Receptor 3; Toll-Like Receptor 7; Toll-Like Receptor 8

2010
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity.
    Vaccine, 2010, Aug-31, Volume: 28, Issue:38

    Topics: Alum Compounds; Aminoquinolines; Animals; Antibodies, Viral; Antigen-Presenting Cells; Cell Differentiation; Cells, Cultured; Dendritic Cells; Hepatitis B Surface Antigens; Humans; Imidazoles; Immunoglobulin G; Interferon-gamma; Interleukin-5; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Quinolines; Spleen; Thiazoles; Toll-Like Receptor 7; Toll-Like Receptor 8

2010
The ultra-potent and selective TLR8 agonist VTX-294 activates human newborn and adult leukocytes.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Adult; Analysis of Variance; Benzazepines; Dendritic Cells; Flow Cytometry; HEK293 Cells; Humans; Imidazoles; Infant, Newborn; Leukocytes; Lipid A; Quinolines; Thiazoles; Toll-Like Receptor 8

2013
Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands.
    Science (New York, N.Y.), 2013, Mar-22, Volume: 339, Issue:6126

    Topics: Amino Acid Sequence; Crystallography, X-Ray; Humans; Hydrogen Bonding; Imidazoles; Ligands; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Protein Binding; Protein Conformation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Quinolines; Signal Transduction; Thiazoles; Toll-Like Receptor 8

2013
Granzyme B expression is enhanced in human monocytes by TLR8 agonists and contributes to antibody-dependent cellular cytotoxicity.
    Journal of immunology (Baltimore, Md. : 1950), 2015, Mar-15, Volume: 194, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Angiotensinogen; Antibodies, Monoclonal, Humanized; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Agents; Blotting, Western; Cells, Cultured; Cetuximab; Cluster Analysis; Dose-Response Relationship, Drug; Granzymes; Humans; Imidazoles; Interleukin-2; Monocytes; NF-kappa B; Oligonucleotide Array Sequence Analysis; Perforin; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Time Factors; Toll-Like Receptor 8; Transcriptome

2015
Design of anti-BVDV drug based on common chemical features, their interaction, and scaffolds of TLR8 agonists.
    International journal of biological macromolecules, 2016, Volume: 92

    Topics: Amino Acid Sequence; Aminoquinolines; Animals; Antiviral Agents; Binding Sites; Cattle; Diarrhea Virus 1, Bovine Viral; Drug Design; Humans; Imidazoles; Imiquimod; Molecular Docking Simulation; Phylogeny; Protein Binding; Protein Domains; Protein Structure, Secondary; Quinolines; Sequence Alignment; Species Specificity; Structural Homology, Protein; Thiazoles; Toll-Like Receptor 8; Viral Nonstructural Proteins

2016
CXCL4 Exposure Potentiates TLR-Driven Polarization of Human Monocyte-Derived Dendritic Cells and Increases Stimulation of T Cells.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 07-01, Volume: 199, Issue:1

    Topics: Antigens, CD; B7-2 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; CD83 Antigen; Cell Differentiation; Cells, Cultured; Coculture Techniques; Dendritic Cells; Escherichia coli; Escherichia coli Infections; Genes, MHC Class I; Humans; Imidazoles; Immunoglobulins; Interleukin-12; Lymphocyte Activation; Membrane Glycoproteins; Phenotype; Platelet Factor 4; Poly I-C; Quinolines; Thiazoles; Tumor Necrosis Factor-alpha

2017