resiniferatoxin and cyclohexadienone

resiniferatoxin has been researched along with cyclohexadienone* in 1 studies

Other Studies

1 other study(ies) available for resiniferatoxin and cyclohexadienone

Article	Year
Diastereoselective phenol para-alkylation: access to a cross-conjugated cyclohexadienone en route to resiniferatoxin. Organic letters, 2004, Nov-11, Volume: 6, Issue:23 We document a route for the synthesis of a densely functionalized spiro-fused 2,5-cyclohexadienone as an intermediate for the synthesis of resineferatoxin. The strategy is based on an unprecedented diastereoselective, intramolecular phenol para-alkylation to a cross-conjugated cyclohexadienone. In the course of these synthetic studies we developed rapid access to a chiral nitrile possessing a quaternary stereocenter and disclose an unusual acetal rearrangement from a dioxane, which favors the corresponding dioxepane. Topics: Alkylation; Cyclohexanes; Cyclohexenes; Diterpenes; Magnetic Resonance Spectroscopy; Phenol; Stereoisomerism	2004

Article

Year

Diastereoselective phenol para-alkylation: access to a cross-conjugated cyclohexadienone en route to resiniferatoxin.

Organic letters, 2004, Nov-11, Volume: 6, Issue:23

We document a route for the synthesis of a densely functionalized spiro-fused 2,5-cyclohexadienone as an intermediate for the synthesis of resineferatoxin. The strategy is based on an unprecedented diastereoselective, intramolecular phenol para-alkylation to a cross-conjugated cyclohexadienone. In the course of these synthetic studies we developed rapid access to a chiral nitrile possessing a quaternary stereocenter and disclose an unusual acetal rearrangement from a dioxane, which favors the corresponding dioxepane.

Topics: Alkylation; Cyclohexanes; Cyclohexenes; Diterpenes; Magnetic Resonance Spectroscopy; Phenol; Stereoisomerism

2004