Page last updated: 2024-08-17

reserpine and probenecid

reserpine has been researched along with probenecid in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199031 (77.50)18.7374
1990's2 (5.00)18.2507
2000's2 (5.00)29.6817
2010's5 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kleinrok, Z; Zebrowska-Lupina, I1
Moussaoui, D1
Moore, KE; Umezu, K1
Beck, O; Sedvall, G; Wiesel, FA1
Bareggi, SR; Genovese, E; Markey, K1
Meyers, D1
Henderson, GB1
Chase, TN2
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
Lycke, E; Roos, BE1
Werdinius, B1
Barkai, A; Glusman, M; Rapport, MM1
Cho, TM; Loh, HH1
Engström, G; Svensson, TH; Waldeck, B1
Kolassa, N; Pfleger, K; Volkmer, I1
Sanders-Bush, E; Sulser, F1
Ahtee, L; Sharman, DF; Vogt, M2
Bowers, MB1
Dresse, A; Gérardy, J; Quinaux, N1
Roffler-Tarlov, S; Sharman, DF; Tegerdine, P1
Sharman, DF1
Brodie, BB; Neef, NH; Tozer, TN1
Downer, RG; Sloley, BD1
Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Pujol, JF; Riou, F1
Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Ponchon, JL; Pujol, JF; Riou, F1
Lamour, Y; Ory-Lavollee, L; Pointis, D; Rivot, JP1
Chiang, CY; Ory-Lavollee, L; Rivot, JP1
Johnston, CA; Moore, KE1
Huff, JW; Reigle, TG1
Azoui, R; Cuche, JL; Dagher, G; Renaud, JF; Safar, M1
SANNER, E1

Reviews

4 review(s) available for reserpine and probenecid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Biochemistry of depression. Literature analysis].
    L'Encephale, 1978, Volume: 4, Issue:3

    Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Dopamine; Humans; Lithium; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Norepinephrine; Probenecid; Reserpine; Serotonin; Synapses; Thyroid Hormones; Tryptophan; Water-Electrolyte Imbalance

1978
Serotonergic mechanisms and extrapyramidal function in man.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extrapyramidal Tracts; Fenclonine; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Imipramine; Levodopa; Muscular Diseases; Paralysis; Parkinson Disease; Parkinson Disease, Secondary; Probenecid; Reserpine; Serotonin; Spinal Cord Diseases; Tetrabenazine; Time Factors

1974
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopamine; Drug-Related Side Effects and Adverse Reactions; Extrapyramidal Tracts; Haloperidol; Humans; Methyltyrosines; Movement Disorders; Phenothiazines; Phenylacetates; Probenecid; Reserpine; Synaptic Transmission; Tetrabenazine; Tranquilizing Agents; Trihexyphenidyl

1972

Other Studies

36 other study(ies) available for reserpine and probenecid

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effect of alpha-adrenolytics on the levels of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in rat's brain.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Adrenergic alpha-Antagonists; Animals; Brain; Brain Chemistry; Butyrophenones; Clonidine; Hydroxyindoleacetic Acid; Levodopa; Male; Phenoxybenzamine; Phentolamine; Probenecid; Rats; Reserpine; Serotonin

1975
Effects of drugs on regional brain concentrations of dopamine and dihydroxyphenylacetic acid.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Brain; Dopamine; Estradiol; Male; Methods; Pargyline; Phenylacetates; Probenecid; Rats; Reserpine

1979
Mass fragmentographic determination of 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid in brain tissue using deuterated internal standards.
    Journal of chromatography, 1977, Apr-11, Volume: 134, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Deuterium; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Male; Microchemistry; Pargyline; Probenecid; Rats; Reserpine; Serotonin; Tryptophan

1977
Short and long-term effects of reserpine on the concentration of 1-(4-hydroxy-3-methoxyphenyl)-ethane-1,2-diol (MOPEG-SO4) in the brain of the rat.
    British journal of pharmacology, 1979, Volume: 65, Issue:4

    Topics: Animals; Brain Chemistry; Electric Stimulation; Glycols; Locus Coeruleus; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Probenecid; Rats; Reserpine; Time Factors

1979
Treatment of calcinosis circumscripta and Raynaud's phenomenon.
    The Medical journal of Australia, 1976, Sep-18, Volume: 2, Issue:12

    Topics: Calcinosis; Female; Humans; Middle Aged; Probenecid; Raynaud Disease; Reserpine

1976
Separation and inhibitor specificity of a second unidirectional efflux route for methotrexate in L1210 cells.
    Biochimica et biophysica acta, 1992, Oct-05, Volume: 1110, Issue:2

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Leukemia L1210; Methotrexate; Mice; Probenecid; Prostaglandins A; Quinidine; Reserpine; Sulfobromophthalein; Tumor Cells, Cultured; Verapamil; Vincristine

1992
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
The monoamine metabolism in viral encephalitides of the mouse. II. Turnover of monoamines in mice infected with herpes simplex virus.
    Brain research, 1972, Sep-29, Volume: 44, Issue:2

    Topics: Animals; Brain; Dihydroxyphenylalanine; Disulfides; Dopamine; Herpes Simplex; Hydroxyindoleacetic Acid; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phenylacetates; Probenecid; Reserpine; Serotonin; Simplexvirus

1972
Effect of probenecid on the level of homovanillic acid in the corpus striatum.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:8

    Topics: Animals; Basal Ganglia; Dopamine; Female; Fluorometry; Haloperidol; Male; Phenylacetates; Probenecid; Rats; Reserpine

1966
Serotonin turnover in the intact cat brain.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:1

    Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Cats; Female; Hydroxyindoleacetic Acid; Kinetics; Male; Methods; Perfusion; Probenecid; Reserpine; Serotonin; Stereotaxic Techniques

1972
Regulation of mouse brain tryptophan hydroxylase activity.
    Pharmacology, 1973, Volume: 10, Issue:4

    Topics: Animals; Brain; Feedback; Hydroxyindoleacetic Acid; Kinetics; Male; Mice; Mixed Function Oxygenases; Norepinephrine; Pargyline; Probenecid; Reserpine; Serotonin; Tryptophan Hydroxylase

1973
Thyroxine and brain catecholamines: increased transmitter synthesis and increased receptor sensitivity.
    Brain research, 1974, Sep-13, Volume: 77, Issue:3

    Topics: Animals; Brain; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Exploratory Behavior; Female; Heart; Homovanillic Acid; Locomotion; Male; Mice; Norepinephrine; Organ Size; Probenecid; Receptors, Adrenergic; Reserpine; Stimulation, Chemical; Thyroxine; Tritium; Tyrosine

1974
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:12

    Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil

1969
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Phenylalanine; Probenecid; Quinolizines; Rats; Reserpine; Serotonin; Tritium; Tryptophan

1970
Acid metabolites of monoamines in avian brain; effects of probenecid and reserpine.
    British journal of pharmacology, 1970, Volume: 38, Issue:1

    Topics: Animals; Behavior, Animal; Biological Transport, Active; Brain; Brain Chemistry; Chickens; Columbidae; Dopamine; Female; Hydroxyindoleacetic Acid; Male; Pargyline; Phenylacetates; Probenecid; Reserpine; Serotonin

1970
5-hydroxyindoleacetic acid in the brain and cerebrospinal fluid of the rabbit following administration of drugs affecting 5-hydroxytryptamine.
    Journal of neurochemistry, 1970, Volume: 17, Issue:6

    Topics: Amino Acids; Animals; Brain; Brain Chemistry; Cerebrospinal Fluid; Hydroxyindoleacetic Acid; Iproniazid; Male; Phenylalanine; Probenecid; Rabbits; Reserpine; Serotonin Antagonists; Tryptophan

1970
[Determination of noradrenaline, of dopamine and dihydroxyphenylacetic acid in certain nuclei of rat brain].
    Experientia, 1971, Jan-15, Volume: 27, Issue:1

    Topics: Animals; Ascorbic Acid; Catecholamines; Caudate Nucleus; Chromatography, Thin Layer; Dihydroxyphenylalanine; Dopamine; Female; Fluorometry; Haloperidol; Hypothalamus; Male; Norepinephrine; Phenylacetates; Probenecid; Rats; Reserpine; Tranylcypromine

1971
3,4-dihydroxyphenylacetic acid and 4-hydroxy-3-methoxyphenylacetic acid in the mouse striatum: a reflection of intra- and extra-neuronal metabolism of dopamine?
    British journal of pharmacology, 1971, Volume: 42, Issue:3

    Topics: Amantadine; Amines; Animals; Basal Ganglia; Cycloparaffins; Dextroamphetamine; Dopamine; Isoquinolines; Ketones; Methyltransferases; Mice; Naphthalenes; Phenylacetates; Probenecid; Reserpine

1971
Effect of probenecid on dopamine metabolites of pigeon brain.
    British journal of pharmacology, 1969, Volume: 36, Issue:1

    Topics: Animals; Brain; Columbidae; Dopamine; Phenylacetates; Probenecid; Reserpine

1969
Changes in the metabolism of 3,4-dihydroxyphenylethylamine (dopamine) in the striatum of the mouse induced by drugs.
    British journal of pharmacology and chemotherapy, 1966, Volume: 28, Issue:2

    Topics: Anesthetics; Animals; Behavior, Animal; Brain; Dopamine; Drug Antagonism; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Methylphenidate; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Morphine; Parasympatholytics; Parasympathomimetics; Pargyline; Phencyclidine; Phenylacetates; Pilocarpine; Probenecid; Reserpine; Tolazoline; Tranquilizing Agents; Tyrosine; Zoxazolamine

1966
Application of seady-state kinetics to studies of the transfer of 5-hydroxyindoleacetic acid from brain to plasma.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2

    Topics: Animals; Biological Transport; Brain; Hydroxyindoleacetic Acid; Kidney Tubules; Kinetics; Male; Pargyline; Probenecid; Rats; Reserpine; Serotonin

1967
Distribution of 5-hydroxytryptamine and indolealkylamine metabolites in the American cockroach, Periplaneta americana L.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cockroaches; Dopamine; Ganglia; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Mitochondria; Monoamine Oxidase; Probenecid; Rats; Reserpine; Serotonin; Species Specificity; Succinate Dehydrogenase; Tryptophan

1984
Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindoleacetic acid in the rat striatum.
    Brain research, 1981, Nov-02, Volume: 223, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Benzyl Alcohols; Clorgyline; Corpus Striatum; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan

1981
In vivo measurements by differential pulse voltammetry of extra-cellular 5-hydroxyindoleacetic acid in the rat brain.
    Journal de physiologie, 1981, Volume: 77, Issue:2-3

    Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Reserpine; Tryptophan

1981
Laminar distribution of serotonergic innervation in rat somatosensory cortex, as determined by in vivo electrochemical detection.
    Brain research, 1983, Jan-17, Volume: 259, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Electrochemistry; Fenclonine; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Somatosensory Cortex

1983
Differential pulse voltammetry in the dorsal horn of the spinal cord of the anesthetized rat: are the voltammograms related to 5-HT and/or to 5-HIAA?
    Brain research, 1983, Sep-26, Volume: 275, Issue:2

    Topics: Animals; Benserazide; Clorgyline; Dose-Response Relationship, Drug; Electric Conductivity; Hydrazines; Hydroxyindoleacetic Acid; Male; Microelectrodes; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Spinal Cord

1983
Measurement of 5-hydroxytryptamine synthesis and metabolism in selected discrete regions of the rat brain using high performance liquid chromatography and electrochemical detection: pharmacological manipulations.
    Journal of neural transmission, 1983, Volume: 57, Issue:1-2

    Topics: Animals; Brain; Corpus Striatum; Hydrazines; Hypothalamus; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan

1983
Effects of morphine and other centrally acting drugs on 3,4-dihydroxyphenylethylene glycol sulfate (DOPEG-SO4) in rat brain.
    Life sciences, 1980, Oct-20, Volume: 27, Issue:16

    Topics: Animals; Brain; Brain Chemistry; Desipramine; Dextroamphetamine; Glycols; Male; Methoxyhydroxyphenylglycol; Morphine; Norepinephrine; Probenecid; Rats; Reserpine; Spectrometry, Fluorescence

1980
A dopamine transporter in human erythrocytes: modulation by insulin.
    Experimental physiology, 1996, Volume: 81, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport; Carrier Proteins; Catecholamines; Choline; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epinephrine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Insulin; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Probenecid; Reserpine; Time Factors

1996
STUDIES ON THE EXCRETION MECHANISM OF SEROTONIN (5-HYDROXYTRYPTAMINE) IN THE CHICKEN KIDNEY.
    Acta physiologica Scandinavica, 1963, Volume: 58

    Topics: Animals; Biological Transport; Chickens; Coloring Agents; Kidney; Kidney Tubules; Physiology; Poultry; Probenecid; Research; Reserpine; Serotonin; Tolazoline; Urine

1963