Page last updated: 2024-08-17

reserpine and idazoxan

reserpine has been researched along with idazoxan in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19907 (24.14)18.7374
1990's15 (51.72)18.2507
2000's4 (13.79)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Nickel, B; Szelenyi, I1
Berlan, M; Estan, L; Montastruc, JL; Senard, JM; Tran, MA1
Hey, JA; Ito, T; Koss, MC1
Hicks, PE; Langer, SZ; Macrae, AD1
Bond, RA; Charlton, KG; Clarke, DE1
Carlsson, M; Eriksson, E; Nilsson, C; Söderpalm, B1
Clark, D; Eriksson, E; Svensson, K1
Paciorek, PM; Shepperson, NB1
Langer, SZ; Pimoule, C; Scatton, B1
Thomas, GP1
Beleslin, DB; Jovanović-Mićić, D; Samardzić, R1
García-Sevilla, JA; Garro, MA; Giralt, MT; Menargues, A; Miralles, A; Obach, R; Olmos, G; Pineda, J; Ugedo, L1
Amabeoku, G; Chandomba, R1
Barturen, F; García-Sevilla, JA; García-Vallejo, P1
Kulkarni, SK; Sharma, A1
Grenhoff, J; Svensson, TH1
Amabeoku, GJ1
O'Farrell, M; Slaughter, M; Ziogas, J1
Aguerre, S; Chaouloff, F; Mormede, P1
Penner, SB; Smyth, DD1
Farley, JT; Klimek, V; Ordway, GA; Zhang, W; Zhu, MY1
Arnsten, AF; Franowicz, JS1
Church, JE; Hodgson, WC1
Busquets, X; García-Sevilla, JA; Miralles, A; Ribas, C1
Brotchie, JM; Fox, SH; Gomez-Ramirez, J; Johnston, TH; Lee, J1
Hashimoto, M; Ono, H; Tanabe, M1
Li, JX; Seaman, RW; Shang, L; Siemian, JN; Zhang, Y; Zhu, Q1

Other Studies

29 other study(ies) available for reserpine and idazoxan

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pharmacological profile of flupirtine, a novel centrally acting, non-opioid analgesic drug.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Adrenergic alpha-Antagonists; Aminopyridines; Analgesics; Animals; Dioxanes; Drug Interactions; Electric Stimulation; Idazoxan; Mice; Muscle Relaxation; Muscle Tonus; Pain Measurement; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Reserpine

1991
Reserpine induces vascular alpha 2-adrenergic supersensitivity and platelet alpha 2-adrenoceptor up-regulation in dog.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: Adipose Tissue; Animals; Blood Platelets; Blood Pressure; Cardiovascular System; Catecholamines; Cell Membrane; Clonidine; Dioxanes; Dogs; Heart Rate; Idazoxan; Male; Norepinephrine; Posture; Prazosin; Receptors, Adrenergic, alpha; Reserpine; Up-Regulation; Yohimbine

1990
Mechanism of dexamphetamine-induced mydriasis in the anaesthetized rat.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Denervation; Dextroamphetamine; Dioxanes; Female; Idazoxan; Male; Methyltyrosines; Oculomotor Nerve; Phenoxybenzamine; Pupil; Rats; Reserpine; Tyrosine 3-Monooxygenase; Urethane; Yohimbine

1989
Differential blocking actions of idazoxan against the inhibitory effects of 6-fluoronoradrenaline and clonidine in the rat vas deferens.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Cocaine; Dioxanes; Dioxins; Electric Stimulation; Idazoxan; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Pargyline; Rats; Reserpine; Vas Deferens

1985
Responses to norepinephrine resistant to inhibition by alpha and beta adrenoceptor antagonists.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Resistance; Guinea Pigs; Idazoxan; Ileum; In Vitro Techniques; Male; Nordefrin; Norepinephrine; Receptors, Adrenergic; Reserpine; Yohimbine

1986
Does alprazolam, in contrast to diazepam, activate alpha 2-adrenoceptors involved in the regulation of rat growth hormone secretion?
    Life sciences, 1986, Apr-21, Volume: 38, Issue:16

    Topics: Adrenergic alpha-Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Clonidine; Diazepam; Dioxanes; Growth Hormone; Idazoxan; Kinetics; Male; Rats; Receptors, Adrenergic, alpha; Reserpine; Yohimbine

1986
The putative dopamine autoreceptor agonist B-HT 920 decreases nigral dopamine cell firing rate and prolactin release in rat.
    Life sciences, 1985, May-13, Volume: 36, Issue:19

    Topics: Action Potentials; Animals; Azepines; Dioxanes; Dopamine; Haloperidol; Idazoxan; Iontophoresis; Male; Neurons; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Substantia Nigra; Trifluoperazine

1985
alpha 1-Adrenoceptor agonist activity of alpha 2-adrenoceptor antagonists in the pithed rat preparation.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxins; Female; Idazoxan; Norepinephrine; Prazosin; Quinolizines; Rats; Rats, Inbred Strains; Reserpine; Spinal Cord

1983
[3H]RX 781094: a new antagonist ligand labels alpha 2-adrenoceptors in the rat brain cortex.
    European journal of pharmacology, 1983, Nov-11, Volume: 95, Issue:1-2

    Topics: Adrenergic alpha-Antagonists; Animals; Benzylamines; Binding, Competitive; Cerebral Cortex; Dioxins; Hydroxydopamines; Idazoxan; Male; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Reserpine

1983
Studies on the protective effect of azepexole on ouabain-induced cardiac arrhythmias and lethality in guinea-pig.
    European journal of pharmacology, 1995, Apr-04, Volume: 276, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Azepines; Blood Pressure; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Dioxanes; Female; Guinea Pigs; Heart Rate; Idazoxan; In Vitro Techniques; Male; Ouabain; Reserpine; Yohimbine

1995
The role of alpha-adrenergic mechanisms within the area postrema in dopamine-induced emesis.
    European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1

    Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Atropine; Cats; Cerebral Ventricles; Dioxanes; Disease Models, Animal; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Hemicholinium 3; Idazoxan; Injections, Intraventricular; Male; Mecamylamine; Methyltyrosines; Methysergide; Naloxone; Oxidopamine; Prazosin; Reserpine; Tolazoline; Tyrosine 3-Monooxygenase; Vomiting; Yohimbine

1995
Acute and chronic effects of reserpine on biochemical and functional parameters of central and peripheral alpha 2-adrenoceptors.
    European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding Sites; Brain; Brimonidine Tartrate; Clonidine; Dihydroxyphenylalanine; Dioxanes; Idazoxan; Injections, Subcutaneous; Male; Mydriasis; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Reserpine; Tyrosine 3-Monooxygenase; Vas Deferens

1993
Strychnine-induced seizures in mice: the role of noradrenaline.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Disulfiram; Droxidopa; Idazoxan; Imipramine; Male; Mice; Pargyline; Phentolamine; Prazosin; Propranolol; Receptors, Adrenergic; Reserpine; Seizures; Strychnine

1994
Modulation by central postsynaptic alpha 2-adrenoceptors of the jaw-opening reflex induced by orofacial stimulation in rats.
    British journal of pharmacology, 1994, Volume: 111, Issue:4

    Topics: Amphetamine; Animals; Brain; Clonidine; Dioxanes; Electric Stimulation; Idazoxan; Jaw; Male; Morphine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex; Reserpine

1994
On the characterization of dopamine-induced contractile response of rat anococcygeus muscle preparation.
    Indian journal of experimental biology, 1994, Volume: 32, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Azepines; Benzazepines; Desipramine; Dioxanes; Dopamine; Female; Haloperidol; Idazoxan; Male; Muscle Contraction; Prazosin; Rats; Receptors, Adrenergic; Receptors, Dopamine; Reserpine; Sulpiride; Yohimbine

1994
Prazosin modulates the firing pattern of dopamine neurons in rat ventral tegmental area.
    European journal of pharmacology, 1993, Mar-16, Volume: 233, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Dioxanes; Dopamine; Idazoxan; In Vitro Techniques; Male; Neural Pathways; Neurons; Norepinephrine; Prazosin; Rats; Rats, Sprague-Dawley; Reserpine; Tegmentum Mesencephali

1993
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
    Experientia, 1993, Oct-15, Volume: 49, Issue:10

    Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Droxidopa; Drug Synergism; Idazoxan; Imipramine; Male; Methyltyrosines; Mice; Norepinephrine; Pargyline; Phentolamine; Physostigmine; Prazosin; Reserpine; Seizures; Serotonin

1993
Caffeine enhances sympathetic purinergic and noradrenergic transmission in the guinea-pig isolated vas deferens.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Caffeine; Dioxanes; Electric Stimulation; Evoked Potentials; Guinea Pigs; Idazoxan; Imidazoles; In Vitro Techniques; Male; Norepinephrine; Receptors, Purinergic; Reserpine; Tritium; Vas Deferens

1995
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
    Neuropharmacology, 1998, Volume: 37, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase

1998
Imidazoline receptor mediated natriuresis: central and/or peripheral effect?
    Journal of the autonomic nervous system, 1998, Oct-15, Volume: 72, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antihypertensive Agents; Brain; Idazoxan; Imidazoles; Imidazoline Receptors; Injections; Injections, Intravenous; Injections, Intraventricular; Kidney; Male; Natriuresis; Peripheral Nervous System; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Drug; Reserpine; Sodium; Sympathectomy

1998
alpha2C adrenoceptors inhibit adenylyl cyclase in mouse striatum: potential activation by dopamine.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Cell Line; Colforsin; Corpus Striatum; Crosses, Genetic; Cyclic AMP; Dopamine; Enzyme Activation; Homozygote; Idazoxan; In Vitro Techniques; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Norepinephrine; Rats; Receptors, Adrenergic, alpha-2; Recombinant Proteins; Reserpine; Transfection

1999
Treatment with the noradrenergic alpha-2 agonist clonidine, but not diazepam, improves spatial working memory in normal young rhesus monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Clonidine; Cognition; Diazepam; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Idazoxan; Macaca mulatta; Memory; Reaction Time; Receptors, Adrenergic, alpha-2; Reserpine; Space Perception

1999
Dose-dependent cardiovascular and neuromuscular effects of stonefish (Synanceja trachynis) venom.
    Toxicon : official journal of the International Society on Toxinology, 2000, Volume: 38, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Atropine; Blood Pressure; Cardiovascular System; Chickens; Coronary Vessels; Fish Venoms; Fishes, Poisonous; Freeze Drying; Heart; Idazoxan; In Vitro Techniques; Muscarinic Antagonists; Muscle, Smooth, Vascular; Neuromuscular Blocking Agents; Propranolol; Quinolines; Rats; Reserpine; Swine

2000
Brain alpha(2)-adrenoceptors in monoamine-depleted rats: increased receptor density, G coupling proteins, receptor turnover and receptor mRNA.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Brain; Brimonidine Tartrate; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Gene Expression Regulation; GTP-Binding Proteins; Idazoxan; Male; Membranes; Norepinephrine; Quinolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reserpine; RNA, Messenger; Tritium

2001
A simple rodent assay for the in vivo identification of agents with potential to reduce levodopa-induced dyskinesia in Parkinson's disease.
    Experimental neurology, 2005, Volume: 191, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amantadine; Animals; Anti-Dyskinesia Agents; Antiparkinson Agents; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Haloperidol; Idazoxan; Levodopa; Male; Motor Activity; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reserpine

2005
Imidazoline I(1) receptor-mediated reduction of muscle rigidity in the reserpine-treated murine model of Parkinson's disease.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Benzazepines; Benzofurans; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Electromyography; Idazoxan; Imidazoles; Imidazoline Receptors; Injections, Intraperitoneal; Ligands; Male; Mice; Muscle Rigidity; Muscle, Skeletal; Parkinsonian Disorders; Reserpine; Time Factors; Yohimbine

2008
Effects of imidazoline I2 receptor agonists on reserpine-induced hyperalgesia and depressive-like behavior in rats.
    Behavioural pharmacology, 2019, Volume: 30, Issue:5

    Topics: Analgesics; Animals; Benzofurans; Depression; Disease Models, Animal; Fibromyalgia; Hyperalgesia; Idazoxan; Imidazoles; Imidazoline Receptors; Imidazolines; Male; Pain; Pain Measurement; Quinazolines; Rats; Rats, Sprague-Dawley; Reserpine

2019