Page last updated: 2024-08-17

reserpine and flupirtine

reserpine has been researched along with flupirtine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Nickel, B; Szelenyi, I2
Borbe, HO; Brune, K; Nickel, B; Szelenyi, I1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

8 other study(ies) available for reserpine and flupirtine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pharmacological profile of flupirtine, a novel centrally acting, non-opioid analgesic drug.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Adrenergic alpha-Antagonists; Aminopyridines; Analgesics; Animals; Dioxanes; Drug Interactions; Electric Stimulation; Idazoxan; Mice; Muscle Relaxation; Muscle Tonus; Pain Measurement; Prazosin; Rats; Rats, Inbred Strains; Reaction Time; Reserpine

1991
Mode of antinociceptive action of flupirtine in the rat.
    British journal of pharmacology, 1989, Volume: 97, Issue:3

    Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Aminopyridines; Analgesics; Animals; Brain Chemistry; Clonidine; Imipramine; Male; Methyltyrosines; Neurotoxins; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Neurotransmitter; Reserpine; Serotonin Antagonists

1989
Putative site(s) and mechanism(s) of action of flupirtine, a novel analgesic compound.
    Postgraduate medical journal, 1987, Volume: 63 Suppl 3

    Topics: Aminopyridines; Analgesics; Animals; Clonidine; Drug Evaluation, Preclinical; Efferent Pathways; Electroencephalography; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Rats; Rats, Inbred Strains; Reserpine; Yohimbine

1987
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009