Page last updated: 2024-08-17

reserpine and clozapine

reserpine has been researched along with clozapine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19908 (29.63)18.7374
1990's6 (22.22)18.2507
2000's6 (22.22)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carroll, BJ; Curtis, GC; Kokmen, E1
Bronzetti, B; Ciriaco, E; Germanà, G; Nisticó, G; Rotiroti, D; Scapagnini, U1
Ljungberg, T1
Palider, W; Przewlocka, B1
Cameron, DS; Deutch, AY1
Christison, GW; Kirch, DG; Wyatt, RJ1
el Mestikawy, S; Glowinski, J; Hamon, M1
Chipkin, RE; Latranyi, MB1
Bronzetti, B; Ciriaco, E; Germanà, G; Nisticò, G1
Gold, R; Lemme, P; Mende, T; Morgenstern, R; Oelssner, W1
Bengtsson, A; Jackson, DM; Malmberg, A; Mohell, N1
Imagawa, Y; Okuyama, S; Tomisawa, K1
Dalack, GW; Healy, DJ; Meador-Woodruff, JH1
Kulkarni, SK; Ninan, I1
Simpson, GM1
Le Pen, G; Moreau, JL1
Ninan, I; Wang, RY1
Crisp, KM; Grupe, RE; Lobsang, TT; Yang, X1

Reviews

3 review(s) available for reserpine and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
When symptoms persist: choosing among alternative somatic treatments for schizophrenia.
    Schizophrenia bulletin, 1991, Volume: 17, Issue:2

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia

1991
The treatment of tardive dyskinesia and tardive dystonia.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 4

    Topics: Adult; Akathisia, Drug-Induced; Algorithms; Antipsychotic Agents; Benzodiazepines; Clozapine; Decision Trees; Drug Administration Schedule; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Male; Olanzapine; Pirenzepine; Probability; Reserpine; Risperidone; Schizophrenia; Substance Withdrawal Syndrome; Tetrabenazine; Treatment Outcome; Vitamin E

2000

Trials

1 trial(s) available for reserpine and clozapine

ArticleYear
When symptoms persist: choosing among alternative somatic treatments for schizophrenia.
    Schizophrenia bulletin, 1991, Volume: 17, Issue:2

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia

1991

Other Studies

24 other study(ies) available for reserpine and clozapine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Paradoxical response to dopamine agonists in tardive dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:7

    Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Apomorphine; Benztropine; Clozapine; Deanol; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Levodopa; Physostigmine; Receptors, Dopamine; Reserpine; Stimulation, Chemical; Thioridazine

1977
Crop-sac response after systemic and intraventricular administration of neuroleptic drugs.
    Neuroendocrinology, 1979, Volume: 29, Issue:6

    Topics: Animals; Antipsychotic Agents; Clozapine; Columbidae; Crop, Avian; Female; Haloperidol; Injections, Intraventricular; Reserpine; Sulpiride

1979
Reliability of two activity boxes commonly used to assess drug induced behavioural changes.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:2

    Topics: Animals; Apomorphine; Clozapine; Dextroamphetamine; Drug Interactions; Evaluation Studies as Topic; Humans; Male; Motor Activity; Phenoxybenzamine; Psychopharmacology; Rats; Reserpine; Stereotyped Behavior

1978
The influence of LSD on the hind limb flexor reflex in the spinal rat.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Animals; Clozapine; Cyproheptadine; Electric Stimulation; Hindlimb; Lysergic Acid Diethylamide; Male; Methyltyrosines; Phenoxybenzamine; Rats; Reflex; Reserpine; Spinal Cord; Time Factors

1975
Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell.
    Neuroscience, 1992, Volume: 46, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Clozapine; Dopamine; Haloperidol; Immobilization; Male; Methyltyrosines; Nucleus Accumbens; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Stress, Psychological; Tyrosine 3-Monooxygenase

1992
Presynaptic dopamine autoreceptors control tyrosine hydroxylase activation in depolarized striatal dopaminergic terminals.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: Amphetamine; Animals; Bucladesine; Cerebral Cortex; Clozapine; Corpus Striatum; Dopamine; Enzyme Activation; Haloperidol; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Sulpiride; Synapses; Synaptosomes; Tyrosine 3-Monooxygenase; Veratridine

1986
Similarity of clozapine and SCH 23390 in reserpinized rats suggests a common mechanism of action.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Clozapine; Dibenzazepines; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Stereotyped Behavior

1987
Morphological changes of pigeon crop-sac mucosa and pituitary lactotrophs after systemic and intraventricular administration of neuroleptic drugs.
    General and comparative endocrinology, 1980, Volume: 41, Issue:2

    Topics: Animals; Antipsychotic Agents; Clozapine; Columbidae; Crop, Avian; Female; Haloperidol; Mucous Membrane; Pituitary Gland, Anterior; Prolactin; Reserpine; Sulpiride

1980
Drug-induced modulation of locomotor hyperactivity induced by picrotoxin in nucleus accumbens.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:4

    Topics: Animals; Apomorphine; Carbachol; Clozapine; Diazepam; Haloperidol; Lisuride; Lysergic Acid Diethylamide; Male; Motor Activity; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Reserpine; Septal Nuclei; Sulpiride

1984
Why does clozapine stimulate the motor activity of reserpine-pretreated rats when combined with a dopamine D1 receptor agonist?
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Clozapine; Dopamine Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Ergolines; Male; Methyltyrosines; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reserpine; Stimulation, Chemical; Tyrosine 3-Monooxygenase

1995
Behavioral evidence for modulation by sigma ligands of (+)MK-801-induced hyperlocomotion in monoamine-depleted mice.
    Neuropharmacology, 1996, Volume: 35, Issue:4

    Topics: alpha-Methyltyrosine; Animals; Anisoles; Biogenic Monoamines; Brain; Catecholamines; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Methyltyrosines; Mice; Mice, Inbred ICR; Motor Activity; Propylamines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Reserpine; Sulpiride

1996
Clozapine-reserpine combination for refractory psychosis.
    Schizophrenia research, 1997, Jun-20, Volume: 25, Issue:3

    Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Humans; Male; Paranoid Disorders; Psychotic Disorders; Reserpine; Treatment Outcome

1997
Partial agonistic action of clozapine at dopamine D2 receptors in dopamine depleted animals.
    Psychopharmacology, 1998, Volume: 135, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Central Nervous System Depressants; Clozapine; Dopamine; Dopamine Agonists; Enzyme Inhibitors; Mice; Motor Activity; Receptors, Dopamine D2; Reserpine; Stereotyped Behavior; Tyrosine 3-Monooxygenase

1998
Disruption of prepulse inhibition of startle reflex in a neurodevelopmental model of schizophrenia: reversal by clozapine, olanzapine and risperidone but not by haloperidol.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002, Volume: 27, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Disease Models, Animal; Haloperidol; Hippocampus; Male; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Reflex, Startle; Reserpine; Schizophrenia

2002
Modulation of the ability of clozapine to facilitate NMDA- and electrically evoked responses in pyramidal cells of the rat medial prefrontal cortex by dopamine: pharmacological evidence.
    The European journal of neuroscience, 2003, Volume: 17, Issue:6

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Benzazepines; Clozapine; Dopamine; Dopamine Agents; Dopamine Antagonists; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Levodopa; Male; N-Methylaspartate; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Reserpine; Synaptic Transmission; Tyrosine 3-Monooxygenase

2003
Biogenic amines modulate pulse rate in the dorsal blood vessel of Lumbriculus variegatus.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2010, Volume: 151, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Antidepressive Agents, Tricyclic; Biogenic Amines; Blood Vessels; Clozapine; Cyproheptadine; Drug Antagonism; Fluoxetine; Heart Rate; Imines; Octopamine; Oligochaeta; Reserpine; Serotonin; Theophylline

2010