repinotan hydrochloride has been researched along with glutamic acid in 4 studies
| Studies (repinotan hydrochloride) | Trials (repinotan hydrochloride) | Recent Studies (post-2010) (repinotan hydrochloride) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 35 | 4 | 1 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | repinotan hydrochloride (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krieglstein, J; Semkova, I; Wolz, P | 1 |
| Ahlemeyer, B; Beier, H; Krieglstein, J; Schaper, C; Semkova, I | 1 |
| Fahrig, T; Horváth, E; Jork, R; Mauler, F | 1 |
| Berends, AC; Luiten, PG; Nyakas, C | 1 |
1 review(s) available for repinotan hydrochloride and glutamic acid
| Article | Year |
|---|---|
A review of the neuroprotective properties of the 5-HT1A receptor agonist repinotan HCl (BAYx3702) in ischemic stroke.
Topics: Animals; Benzopyrans; Disease Models, Animal; Glutamic Acid; Humans; Models, Biological; Nerve Growth Factors; Neuroprotective Agents; Piperazines; Pyridines; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serotonin 5-HT1 Receptor Agonists; Signal Transduction; Stroke; Thiazoles | 2005 |
3 other study(ies) available for repinotan hydrochloride and glutamic acid
| Article | Year |
|---|---|
Neuroprotective effect of 5-HT1A receptor agonist, Bay X 3702, demonstrated in vitro and in vivo.
Topics: Animals; Benzopyrans; Brain; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Neurons; Rats; Rats, Inbred F344; Rats, Long-Evans; Serotonin Receptor Agonists; Thiazoles | 1998 |
S-100beta protects cultured neurons against glutamate- and staurosporine-induced damage and is involved in the antiapoptotic action of the 5 HT(1A)-receptor agonist, Bay x 3702.
Topics: Animals; Animals, Newborn; Antibodies; Apoptosis; Astrocytes; Benzopyrans; Cell Survival; Cells, Cultured; Chick Embryo; Coculture Techniques; Corpus Striatum; Cytoprotection; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Nerve Growth Factors; Neurons; Neuroprotective Agents; Piperazines; Pyridines; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Serotonin Antagonists; Staurosporine; Thiazoles | 2000 |
Inhibition of evoked glutamate release by the neuroprotective 5-HT(1A) receptor agonist BAY x 3702 in vitro and in vivo.
Topics: Animals; Aspartic Acid; Benzopyrans; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Male; Microdialysis; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Synaptic Transmission; Thiazoles | 2001 |