renzapride has been researched along with metoclopramide in 11 studies
| Studies (renzapride) | Trials (renzapride) | Recent Studies (post-2010) (renzapride) | Studies (metoclopramide) | Trials (metoclopramide) | Recent Studies (post-2010) (metoclopramide) |
|---|---|---|---|---|---|
| 70 | 12 | 2 | 5,044 | 1,216 | 623 |
| Protein | Taxonomy | renzapride (IC50) | metoclopramide (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.383 | |
| Myeloperoxidase | Homo sapiens (human) | 0.35 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.721 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.8 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.127 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 7.8 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.7 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 3.675 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.383 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 7.8 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 7.8 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.2 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.88 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.63 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 7.8 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.6237 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.88 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Drenth, JP; Engels, LG | 1 |
| Gullikson, GW; Loeffler, RF; Viriña, MA | 1 |
| Pennick, M; Staniforth, DH | 1 |
| Bockaert, J; Dumuis, A; Sebben, M | 1 |
| Rose, D; Staniforth, DH | 1 |
| Cooper, SM; Evans, DF; Ledingham, SJ; Robertson, CS | 1 |
| Gullikson, GW; Nemeth, PR | 1 |
| Miner, WD; Sanger, GJ; Turner, DH | 1 |
| Andrews, PL; Hawthorn, J; Ostler, KJ | 1 |
| Buchheit, KH; Buhl, T | 1 |
| Pilot, MA; Qin, XY; Scott, M; Thompson, H | 1 |
1 review(s) available for renzapride and metoclopramide
| Article | Year |
|---|---|
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes Complications; Domperidone; Double-Blind Method; Erythromycin; Gastric Emptying; Humans; Metoclopramide; Piperidines; Stomach Diseases | 1992 |
4 trial(s) available for renzapride and metoclopramide
| Article | Year |
|---|---|
Diabetic gastroparesis. A critical reappraisal of new treatment strategies.
Topics: Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Diabetes Complications; Domperidone; Double-Blind Method; Erythromycin; Gastric Emptying; Humans; Metoclopramide; Piperidines; Stomach Diseases | 1992 |
Human pharmacology of renzapride: a new gastrokinetic benzamide without dopamine antagonist properties.
Topics: Adult; Benzamides; Breath Tests; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Gastric Emptying; Gastrointestinal Transit; Humans; Lactulose; Male; Metoclopramide; Prolactin; Random Allocation | 1990 |
The variability in oro-cecal transit time assessed using a bean-based test meal and its use in the study of the effect of metoclopramide and BRL 24924 on transit time.
Topics: Adult; Benzamides; Breath Tests; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Fabaceae; Female; Food; Gastrointestinal Transit; Humans; Hydrogen-Ion Concentration; Male; Metoclopramide; Plants, Medicinal; Receptors, Serotonin | 1989 |
A double-blind dose ranging study of BRL 24924 and metoclopramide on lower oesophageal sphincter pressure in healthy volunteers.
Topics: Adult; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Double-Blind Method; Esophagogastric Junction; Humans; Male; Manometry; Metoclopramide; Pressure; Receptors, Serotonin | 1989 |
7 other study(ies) available for renzapride and metoclopramide
| Article | Year |
|---|---|
Relationship of serotonin-3 receptor antagonist activity to gastric emptying and motor-stimulating actions of prokinetic drugs in dogs.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Cisplatin; Dogs; Dose-Response Relationship, Drug; Female; Gastric Emptying; Gastrointestinal Motility; Indoles; Injections, Intravenous; Male; Metoclopramide; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Tropisetron | 1991 |
BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons.
Topics: Adenylyl Cyclases; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cyclic AMP; Embryo, Mammalian; Female; Indoles; Metoclopramide; Mice; Neurons; Pregnancy; Serotonin Antagonists; Tropisetron | 1989 |
Gastrointestinal motility stimulating drugs and 5-HT receptors on myenteric neurons.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Electrophysiology; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Indoles; Male; Metoclopramide; Myenteric Plexus; Neurons; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tropisetron | 1989 |
Evidence that 5-hydroxytryptamine3 receptors mediate cytotoxic drug and radiation-evoked emesis.
Topics: Animals; Antineoplastic Agents; Apomorphine; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Cisplatin; Cyclophosphamide; Domperidone; Doxorubicin; Ferrets; Male; Metoclopramide; Receptors, Serotonin; Vomiting; Whole-Body Irradiation | 1987 |
The role of the abdominal visceral innervation and 5-hydroxytryptamine M-receptors in vomiting induced by the cytotoxic drugs cyclophosphamide and cis-platin in the ferret.
Topics: Animals; Antiemetics; Apomorphine; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Carnivora; Cisplatin; Cyclophosphamide; Female; Ferrets; Male; Metoclopramide; Receptors, Serotonin; Splanchnic Nerves; Vagotomy; Vomiting | 1988 |
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ligands; Male; Metoclopramide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Tetrodotoxin; Tropanes; Tropisetron | 1994 |
Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis.
Topics: Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Dogs; Electromyography; Erythromycin; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Injections, Intravenous; Intestine, Small; Male; Metoclopramide; Muscle Contraction; Muscle, Smooth; Serotonin Antagonists; Tropanes; Vomiting | 1993 |