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remacemide and 1-methyl-1,2-diphenylethylamine monohydrochloride

remacemide has been researched along with 1-methyl-1,2-diphenylethylamine monohydrochloride in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (50.00)18.2507
2000's7 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coenen, AM; van Luijtelaar, EL1
Donevan, SD; Rogawski, MA; Subramaniam, S1
Davies, JA; Richens, A; Srinivasan, J1
Cheung, H; Harris, EW; McLean, MJ; Wamil, AW1
Meldrum, BS1
Davies, JA; Hu, RQ1
King, AE; Norris, SK1
Asghar, AU; Hasan, SS; King, AE2
Schachter, SC; Tarsy, D1
Brodie, MJ; McNeill, C; Santangeli, S; Sills, GJ1
Avanzini, G; Ientile, R; Macaione, V; Oteri, G; Pedale, S; Pisani, F; Torre, V1
Brodie, MJ; Santangeli, S; Sills, GJ; Stone, TW1
Brodie, MJ; Santangeli, S; Sills, GJ; Thompson, GG1

Reviews

2 review(s) available for remacemide and 1-methyl-1,2-diphenylethylamine monohydrochloride

ArticleYear
Update on the mechanism of action of antiepileptic drugs.
    Epilepsia, 1996, Volume: 37 Suppl 6

    Topics: 4-Aminobutyrate Transaminase; Acetamides; Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Ion Channels; Lamotrigine; Membrane Potentials; Mice; Neurotransmitter Agents; Nipecotic Acids; Phenethylamines; Phenylcarbamates; Propylene Glycols; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin

1996
Remacemide: current status and clinical applications.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:4

    Topics: Acetamides; Animals; Anticonvulsants; Brain Ischemia; Epilepsy; Excitatory Amino Acid Antagonists; Humans; Huntington Disease; Intraoperative Complications; Neuroprotective Agents; Parkinson Disease; Phenethylamines; Receptors, N-Methyl-D-Aspartate

2000

Other Studies

12 other study(ies) available for remacemide and 1-methyl-1,2-diphenylethylamine monohydrochloride

ArticleYear
Effects of remacemide and its metabolite FPL 12495 on spike-wave discharges, electroencephalogram and behaviour in rats with absence epilepsy.
    Neuropharmacology, 1995, Volume: 34, Issue:4

    Topics: Acetamides; Action Potentials; Animals; Anticonvulsants; Behavior, Animal; Electroencephalography; Epilepsy, Absence; Male; Phenethylamines; Rats; Rats, Inbred Strains

1995
Block of the N-methyl-D-aspartate receptor by remacemide and its des-glycine metabolite.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Acetamides; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Kinetics; Membrane Potentials; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenethylamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Spermine; Tritium

1996
The effect of the desglycinyl metabolite of remacemide hydrochloride (FPL 12495AA) and dizocilpine (MK-801) on endogenous amino acid release from mouse cortex.
    British journal of pharmacology, 1995, Volume: 116, Issue:8

    Topics: Acetamides; Animals; Anticonvulsants; Aspartic Acid; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Phenethylamines; Potassium; Veratridine

1995
Remacemide HCl and its metabolite, FPL 12495AA, limit action potential firing frequency and block NMDA responses of mouse spinal cord neurons in cell culture.
    Epilepsy research, 1996, Volume: 23, Issue:1

    Topics: Acetamides; Action Potentials; Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Neurons; Phenethylamines; Receptors, N-Methyl-D-Aspartate; Spinal Cord

1996
The effect of the desglycinyl metabolite of remacemide on cortical wedges prepared from DBA/2 mice.
    European journal of pharmacology, 1995, Dec-20, Volume: 287, Issue:3

    Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Anticonvulsants; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Female; Ion Channels; Male; Membrane Potentials; Mice; N-Methylaspartate; Phencyclidine; Phenethylamines; Receptors, N-Methyl-D-Aspartate; Reference Values

1995
Electrophysiological effects of the anticonvulsant remacemide hydrochloride and its metabolite ARL 12495AA on rat CA1 hippocampal neurons in vitro.
    Neuropharmacology, 1997, Volume: 36, Issue:7

    Topics: Acetamides; Action Potentials; Animals; Anticonvulsants; Female; Hippocampus; In Vitro Techniques; Neurons; Phenethylamines; Rats; Rats, Wistar

1997
The anticonvulsant remacemide and its metabolite AR-R12495AA attenuate spinal synaptic transmission and carrageenan-induced inflammation in the young rat.
    European journal of pain (London, England), 2000, Volume: 4, Issue:1

    Topics: Acetamides; Animals; Anterior Horn Cells; Anticonvulsants; Carrageenan; Electrophysiology; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inflammation; Membrane Potentials; Neurons, Afferent; Phenethylamines; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission

2000
Actions of the anticonvulsant remacemide metabolite AR-R12495AA on afferent-evoked spinal synaptic transmission in vitro and on models of acute and chronic inflammation in the rat.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Acetamides; Acute Disease; Afferent Pathways; Animals; Animals, Newborn; Anticonvulsants; Chronic Disease; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Hyperalgesia; In Vitro Techniques; Inflammation; Phenethylamines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission

2000
Simultaneous determination of remacemide hydrochloride and desglycinylremacemide (AR-R12495XX) in brain tissue by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Sep-15, Volume: 746, Issue:2

    Topics: Acetamides; Animals; Brain; Chromatography, High Pressure Liquid; Male; Mice; Mice, Inbred ICR; Phenethylamines; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

2000
Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina.
    Experimental neurology, 2001, Volume: 170, Issue:1

    Topics: Acetamides; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Chick Embryo; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kainic Acid; L-Lactate Dehydrogenase; Lamotrigine; N-Methylaspartate; Necrosis; Neuroprotective Agents; Phenethylamines; Retina; Retinal Ganglion Cells; Triazines

2001
Differential effects of remacemide and desglycinyl-remacemide on epileptiform burst firing in the rat hippocampal slice.
    Neuroscience letters, 2002, Mar-15, Volume: 321, Issue:1-2

    Topics: 4-Aminopyridine; Acetamides; Action Potentials; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Antagonists; Hippocampus; Magnesium Deficiency; Male; Neurons; Phenethylamines; Pyridines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Sodium Channels

2002
Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes.
    European journal of pharmacology, 2002, Mar-01, Volume: 438, Issue:1-2

    Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; Lamotrigine; Male; Phenethylamines; Phenytoin; Rats; Rats, Wistar; Sodium; Sodium Channels; Synaptosomes; Tetrodotoxin; Triazines; Veratridine

2002