Page last updated: 2024-09-05

regadenoson and uk-432097

regadenoson has been researched along with uk-432097 in 2 studies

Compound Research Comparison

Studies (regadenoson)	Trials (regadenoson)	Recent Studies (post-2010) (regadenoson)	Studies (uk-432097)	Trials (uk-432097)	Recent Studies (post-2010) (uk-432097)
321	53	264	9	0	8

Protein Interaction Comparison

Protein	Taxonomy	regadenoson (IC50)	uk-432097 (IC50)
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)		0.004
Adenosine receptor A2a	Homo sapiens (human)		0.004

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Deflorian, F; Gao, ZG; Jacobson, KA; Katritch, V; Kumar, TS; Phan, K; Stevens, RC; Wu, H; Xu, F	1
Aghazadeh Tabrizi, M; Baraldi, PG; Baraldi, S; Borea, PA; Bruno, A; Cosconati, S; Novellino, E; Preti, D; Ravani, A; Romagnoli, R; Saponaro, G; Varani, K; Vincenzi, F	1

Other Studies

2 other study(ies) available for regadenoson and uk-432097

Article	Year
Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Adenosine; Adenosine A2 Receptor Agonists; Amino Acids; Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Models, Molecular; Nucleosides; Phenethylamines; Protein Conformation; Radioligand Assay; Receptor, Adenosine A2A; Stereoisomerism; Structure-Activity Relationship; Thermodynamics	2012
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor. Journal of medicinal chemistry, 2015, Apr-09, Volume: 58, Issue:7 Topics: Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Chemistry Techniques, Synthetic; CHO Cells; Cricetulus; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Docking Simulation; Receptor, Adenosine A2A; Structure-Activity Relationship	2015

Article

Year

Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.

Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

Topics: Adenosine; Adenosine A2 Receptor Agonists; Amino Acids; Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Models, Molecular; Nucleosides; Phenethylamines; Protein Conformation; Radioligand Assay; Receptor, Adenosine A2A; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

2012

Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor.

Journal of medicinal chemistry, 2015, Apr-09, Volume: 58, Issue:7

Topics: Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Chemistry Techniques, Synthetic; CHO Cells; Cricetulus; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Docking Simulation; Receptor, Adenosine A2A; Structure-Activity Relationship

2015