Page last updated: 2024-09-05

regadenoson and dipyridamole

regadenoson has been researched along with dipyridamole in 18 studies

Compound Research Comparison

Studies
(regadenoson)
Trials
(regadenoson)
Recent Studies (post-2010)
(regadenoson)
Studies
(dipyridamole)
Trials
(dipyridamole)
Recent Studies (post-2010) (dipyridamole)
321532647,826881632

Protein Interaction Comparison

ProteinTaxonomyregadenoson (IC50)dipyridamole (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)21.0682
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)21.0682
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1233
Solute carrier family 22 member 2Homo sapiens (human)2.6
Multidrug resistance-associated protein 4Homo sapiens (human)5.15
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.6333
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.9708
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)5.835
Bile salt export pumpHomo sapiens (human)4
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.956
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.6333
Exopolyphosphatase PRUNE1Homo sapiens (human)0.78
Equilibrative nucleoside transporter 1Homo sapiens (human)0.0537
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6.4

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (11.11)29.6817
2010's14 (77.78)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cerqueira, MD1
Druz, RS1
Bengel, FM; Bravo, P; Fukushima, K; Goudarzi, B; Merrill, J1
Abraham, MR; Abraham, TP; Bengel, FM; Bravo, PE; Merrill, J; Pinheiro, A; Pozios, I; Tsui, BM; Wahl, RL1
Bateman, TM; Case, JA; Courter, SA; Cullom, SJ; McGhie, AI1
Boulanger, L; Friedman, M; Gatt, E; Kothari, S; Spalding, J; Wu, Y1
Breeze, J; Hudgens, S; Spalding, J1
Arai, AE; Bandettini, WP; Booker, OJ; Hsu, LY; Kellman, P; Leung, S; Mancini, C; Shanbhag, SM; Vasu, S; Wilson, J1
Bremerich, J; Kawel-Boehm, N1
Gould, KL; Johnson, NP1
Dilsizian, V; Narula, J1
Amer, KA; Cohen, G; Edwin, SB; Hurren, JR1
Babar, AK; Bui, L; DeGolovine, A; Gould, KL; Johnson, NP; Kitkungvan, D; Kumar, S; Madjid, M; Nacimbene, A; Patel, MB; Roby, AE; Vejpongsa, P1
Al Badarin, F; Bateman, TM; Case, JA; Chan, PS; Courter, S; Heller, GV; Kennedy, KF; McGhie, AI; Patel, KK; Spertus, JA1
Ahmed, A; Ahmed, D; Al-Mallah, M; Alali Alfaris, M; Alharthi, M; Aljizeeri, A; Alsaileek, A; Elneama, A; Farea, J; Suliman, I1
Angoulvant, D; Bailly, M; Brana, Q; Courtehoux, M; Metrard, G; Ribeiro, MJ; Thibault, F1
Carafa, MRP; Flammia, FC; Larici, AR; Lo Piccolo, F; Marano, R; Meduri, A; Merlino, B; Natale, L; Rovere, G; Savino, G1

Reviews

5 review(s) available for regadenoson and dipyridamole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in pharmacologic agents in imaging: new A2A receptor agonists.
    Current cardiology reports, 2006, Volume: 8, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Coronary Vessels; Cyclohexanecarboxylic Acids; Dipyridamole; Heart; Humans; Organotechnetium Compounds; Purines; Pyrazoles; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2006
Current advances in vasodilator pharmacological stress perfusion imaging.
    Seminars in nuclear medicine, 2009, Volume: 39, Issue:3

    Topics: Adenosine; Adult; Contraindications; Coronary Artery Disease; Dipyridamole; Exercise Test; Female; Humans; Myocardial Perfusion Imaging; Purines; Pyrazoles; Radiopharmaceuticals; Vasodilator Agents

2009
Magnetic resonance stress imaging of myocardial perfusion and wall motion.
    Journal of thoracic imaging, 2014, Volume: 29, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Cardiotonic Agents; Coronary Angiography; Dipyridamole; Exercise Test; Humans; Magnetic Resonance Imaging; Myocardial Perfusion Imaging; Purines; Pyrazoles; Vasodilator Agents

2014
Practical instructions for using drugs in CT and MR cardiac imaging.
    La Radiologia medica, 2021, Volume: 126, Issue:3

    Topics: Adenosine; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Atropine; Calcium Channel Blockers; Cardiac Imaging Techniques; Computed Tomography Angiography; Contraindications, Drug; Coronary Angiography; Coronary Vessels; Dipyridamole; Dobutamine; Heart; Humans; Ivabradine; Magnetic Resonance Imaging; Nitroglycerin; Purines; Pyrazoles; Vasodilator Agents

2021

Trials

2 trial(s) available for regadenoson and dipyridamole

ArticleYear
Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity.
    European heart journal. Cardiovascular Imaging, 2019, Jul-01, Volume: 20, Issue:7

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Caffeine; Cardiovascular Diseases; Coronary Circulation; Dipyridamole; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purines; Pyrazoles

2019
Randomized Comparison of Clinical Effectiveness of Pharmacologic SPECT and PET MPI in Symptomatic CAD Patients.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Agents; Comparative Effectiveness Research; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary Stenosis; Dipyridamole; Female; Health Status; Humans; Kansas; Male; Middle Aged; Myocardial Perfusion Imaging; Myocardial Revascularization; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Prospective Studies; Purines; Pyrazoles; Referral and Consultation; Severity of Illness Index; Single Photon Emission Computed Tomography Computed Tomography; Time Factors; Treatment Outcome; Vasodilator Agents

2019

Other Studies

11 other study(ies) available for regadenoson and dipyridamole

ArticleYear
Comparison of the myocardial blood flow response to regadenoson and dipyridamole: a quantitative analysis in patients referred for clinical 82Rb myocardial perfusion PET.
    European journal of nuclear medicine and molecular imaging, 2011, Volume: 38, Issue:10

    Topics: Coronary Circulation; Dipyridamole; Female; Hemodynamics; Humans; Injections; Male; Middle Aged; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purinergic P1 Receptor Agonists; Purines; Pyrazoles; Retrospective Studies; Rubidium Radioisotopes; Stress, Physiological

2011
Comparison and effectiveness of regadenoson versus dipyridamole on stress electrocardiographic changes during positron emission tomography evaluation of patients with hypertrophic cardiomyopathy.
    The American journal of cardiology, 2012, Oct-01, Volume: 110, Issue:7

    Topics: Adenosine A2 Receptor Antagonists; Cardiomyopathy, Hypertrophic; Coronary Circulation; Dipyridamole; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Humans; Injections, Intravenous; Male; Middle Aged; Positron-Emission Tomography; Purines; Pyrazoles; Reproducibility of Results; Retrospective Studies; ROC Curve; Severity of Illness Index; Stroke Volume; Vasodilator Agents

2012
Regadenoson pharmacologic rubidium-82 PET: a comparison of quantitative perfusion and function to dipyridamole.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013, Volume: 20, Issue:1

    Topics: Aged; Blood Pressure; Body Mass Index; Chlorides; Dipyridamole; Exercise Test; Female; Hemodynamics; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Myocardial Perfusion Imaging; Perfusion; Positron-Emission Tomography; Purines; Pyrazoles; Radiopharmaceuticals; Rubidium; Rubidium Radioisotopes; Ventricular Function, Left

2013
Myocardial perfusion imaging laboratory efficiency with the use of regadenoson compared to adenosine and dipyridamole.
    Journal of medical economics, 2013, Volume: 16, Issue:4

    Topics: Adenosine; Coronary Artery Disease; Data Collection; Dipyridamole; Health Personnel; Humans; Myocardial Perfusion Imaging; Nuclear Medicine Department, Hospital; Purines; Pyrazoles; Receptor, Adenosine A2A; Time Factors; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2013
Patient- and clinician-reported satisfaction with pharmacological stress agents for single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI).
    Journal of medical economics, 2013, Volume: 16, Issue:6

    Topics: Adenosine A2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Dipyridamole; Female; Humans; Male; Medical Staff, Hospital; Middle Aged; Myocardial Perfusion Imaging; Outcome Assessment, Health Care; Patient Satisfaction; Purines; Pyrazoles; Self Report; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2013
Regadenoson and adenosine are equivalent vasodilators and are superior than dipyridamole- a study of first pass quantitative perfusion cardiovascular magnetic resonance.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2013, Sep-24, Volume: 15

    Topics: Adenosine; Coronary Circulation; Dipyridamole; Female; Healthy Volunteers; Heart Rate; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Myocardial Perfusion Imaging; Predictive Value of Tests; Purines; Pyrazoles; Vasodilation; Vasodilator Agents; Young Adult

2013
Regadenoson versus dipyridamole hyperemia for cardiac PET imaging.
    JACC. Cardiovascular imaging, 2015, Volume: 8, Issue:4

    Topics: Adenosine A2 Receptor Agonists; Adult; Aged; Dipyridamole; Female; Heart Diseases; Hemodynamics; Humans; Hyperemia; Male; Middle Aged; Positron-Emission Tomography; Purines; Pyrazoles; Vasodilator Agents

2015
Capturing maximal coronary vasodilation for myocardial perfusion imaging: is timing everything?
    JACC. Cardiovascular imaging, 2015, Volume: 8, Issue:4

    Topics: Adenosine A2 Receptor Agonists; Dipyridamole; Humans; Hyperemia; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purines; Pyrazoles; Sensitivity and Specificity; Time Factors; Tomography, Emission-Computed, Single-Photon; Vasodilation; Vasodilator Agents

2015
Regadenoson versus Dipyridamole: A Comparison of the Frequency of Adverse Events in Patients Undergoing Myocardial Perfusion Imaging.
    Pharmacotherapy, 2017, Volume: 37, Issue:6

    Topics: Adenosine A2 Receptor Agonists; Aged; Cohort Studies; Cost-Benefit Analysis; Dipyridamole; Dyspnea; Female; Gastrointestinal Diseases; Heart Diseases; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Purines; Pyrazoles; Retrospective Studies; Vasodilator Agents

2017
Are Patients With End-Stage Liver Disease Maximally Vasodilated?: Insights From Rubidium-82 PET Dilatory Perfusion.
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:12

    Topics: Aged; Coronary Artery Disease; Dipyridamole; End Stage Liver Disease; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Purines; Pyrazoles; Radiopharmaceuticals; Retrospective Studies; Rubidium Radioisotopes; Vasodilation; Vasodilator Agents

2019
Regadenoson versus dipyridamole: Evaluation of stress myocardial blood flow response on a CZT-SPECT camera.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:1

    Topics: Coronary Circulation; Dipyridamole; Humans; Hyperemia; Myocardial Perfusion Imaging; Purines; Pyrazoles; Retrospective Studies; Tomography, Emission-Computed, Single-Photon

2022