Page last updated: 2024-09-05

regadenoson and adenosine

regadenoson has been researched along with adenosine in 54 studies

Compound Research Comparison

Studies
(regadenoson)
Trials
(regadenoson)
Recent Studies (post-2010)
(regadenoson)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
3215326432,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomyregadenoson (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (25.93)29.6817
2010's35 (64.81)24.3611
2020's5 (9.26)2.80

Authors

AuthorsStudies
Deflorian, F; Gao, ZG; Jacobson, KA; Katritch, V; Kumar, TS; Phan, K; Stevens, RC; Wu, H; Xu, F1
de Lera Ruiz, M; Lim, YH; Zheng, J1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fan, S; Li, S; Xie, F; Zhang, M; Zhong, W; Zhou, X1
Baker, SP; Belardinelli, L; Blackburn, B; Elzein, E; Gao, Z; Lasley, RD; Li, Z; Meyer, S; Palle, V; Zablocki, JA1
Belardinelli, L; Belloni, F; Hintze, TH; Linke, A; Ochoa, M; Xu, X; Zhao, G1
Bateman, TM; Blackburn, B; Cerqueira, MD; Hendel, RC; Iskandrian, AE; Leppo, JA; Mahmarian, JJ1
Cerqueira, MD1
Mitka, M1
Botvinick, EH1
Belardinelli, L; Blackburn, B; Franks, B; Hage, FG; Heo, J; Iskandrian, AE; Wang, W1
Druz, RS1
Cerqueira, MD; Iskandrian, AE; Nguyen, P; Staehr, P; Underwood, SR1
Udelson, JE2
Bateman, TM; Cerqueira, MD; Hendel, RC; Iskandrian, AE; Mahmarian, JJ; Moye, LA; Olmsted, AW; Thomas, GS1
Belardinelli, L; Dione, DP; Jadbabaie, F; Mekkaoui, C; Meoli, DF; Purushothaman, K; Sinusas, AJ1
Dilsizian, V1
Curran, MP; Garnock-Jones, KP1
Hage, FG; Heo, J; Iskandrian, AE; Perry, G1
Belardinelli, L; Clarke, KA; Miyamoto, MI; Thomas, GS1
Ananthasubramaniam, K; Barboza, J; Cavalcante, JL1
Adluru, G; Chen, L; DiBella, EV; Fluckiger, JU; Jiji, R; Kim, TH; Kuppahally, S; Litwin, SE; Matthews, B; McGann, C; Pack, NA; Priester, T1
Pijls, NH; Tonino, PA1
Ahmed, A; Dean, PJ; Hage, FG; Heo, J; Iqbal, FM; Iskandrian, AE; Raslan, S1
Arumugham, P; Figueredo, VM; Morris, DL; Patel, PB1
Boulanger, L; Friedman, M; Gatt, E; Kothari, S; Spalding, J; Wu, Y1
Clavijo, LC; Doherty, R; Gopal, A; Matthews, RV; Mehra, A; Prasad, A; Shavelle, DM; Somma, K; Vora, H; Zareh, M1
Biederman, RW; Dishart, MK; Doyle, M; Fakhri, AA; Grant, SB; Nathan, S; Oliva, J; Poydence, J; Reddy, ST; Shah, M; Singh, A; Thai, NL; Tom, KB; Williams, RB; Yamrozik, JA1
Arai, AE; Bandettini, WP; Booker, OJ; Hsu, LY; Kellman, P; Leung, S; Mancini, C; Shanbhag, SM; Vasu, S; Wilson, J1
Dziuk, M; Kocki, J; Pińkowski, R; Tkaczewski, K1
Kinser, CR; Kristy, R; Mahmarian, JJ; Thomas, GS; Xu, J1
Bremerich, J; Kawel-Boehm, N1
Hakeem, A; Uretsky, B1
Bayer, RR; De Cecco, CN; Harris, BS; Krazinski, AW; McWhite, CB; Meinel, FG; Schoepf, UJ; Silverman, JR1
Bateman, TM; Cerqueira, MD; Iskandrian, AE; Mahmarian, JJ; Nabi, F; Peterson, LE; Thomas, GS; Xu, J1
Amano, T; Doh, JH; Kato, D; Kim, HS; Koo, BK; Kurita, A; Lim, WH; Nam, CW; Oi, M; Park, JJ; Park, KW; Pijls, NH; Takashima, H; Toyofuku, M; van Nunen, L; Waseda, K; Yang, HM1
Captur, G; Greenwood, JP; Herrey, AS; Manisty, C; Moon, JC; Peebles, C; Petersen, SE; Plein, S; Ripley, DP; Schelbert, EB; Wong, TC1
Borges-Neto, S; Dunning, A; Farzaneh-Far, A; O'Connor, CM; Oldan, JD; Shaw, LK1
Basu, S1
Brink, HL; Dickerson, JA; Pickworth, KK; Stephens, JA1
Kawaji, K; Kramer, CM; Lang, RM; Mor-Avi, V; Nathan, S; Patel, AR; Patel, MB1
Arumugam, P; Memmott, MJ; Saint, KJ; Tonge, CM1
Kaandorp, TAM; Kuijpers, D; Oudkerk, M; van der Harst, P; van Dijk, R; van Dijkman, PRM; Vliegenthart, R1
Andrikopoulou, E; Bajaj, NS; Brice, L; Doppalapudi, H; Hage, FG; Iskandrian, AE; Morgan, CJ1
Aden, JK; Lisanti, CJ; Minor, MR; Steel, KE; Thomas, DM1
Bober, R; Edward, JA; Lee, JH; Morin, DP; White, CJ1
Aaronson, K; Colvin, M; Corbett, JR; Ghannam, M; Koelling, T; Konerman, MC; Lazarus, JJ; Murthy, VL; Pagani, F; Saleh, A; Weinberg, RL1
Babar, AK; Bui, L; DeGolovine, A; Gould, KL; Johnson, NP; Kitkungvan, D; Kumar, S; Madjid, M; Nacimbene, A; Patel, MB; Roby, AE; Vejpongsa, P1
Borah, P; Deb, PK; Deka, S; Mailavaram, RP1
Carafa, MRP; Flammia, FC; Larici, AR; Lo Piccolo, F; Marano, R; Meduri, A; Merlino, B; Natale, L; Rovere, G; Savino, G1
García Gonzalez, MP; Higueras Ortega, L; Lopez-Lereu, MP; Maceira Gonzalez, AM; Monmeneu Menadas, JV1
Kero, T; Knuuti, J; Lagerqvist, B; Lubberink, M; Pikkarainen, E; Saraste, A; Sörensen, J1
Caobelli, F; Clerc, OF; Frey, SM; Haaf, P; Honegger, U; Zellweger, MJ1

Reviews

10 review(s) available for regadenoson and adenosine

ArticleYear
Adenosine A2A receptor as a drug discovery target.
    Journal of medicinal chemistry, 2014, May-08, Volume: 57, Issue:9

    Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction

2014
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Advances in pharmacologic agents in imaging: new A2A receptor agonists.
    Current cardiology reports, 2006, Volume: 8, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Coronary Vessels; Cyclohexanecarboxylic Acids; Dipyridamole; Heart; Humans; Organotechnetium Compounds; Purines; Pyrazoles; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2006
Current methods of pharmacologic stress testing and the potential advantages of new agents.
    Journal of nuclear medicine technology, 2009, Volume: 37, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Coronary Disease; Dobutamine; Exercise Test; Humans; Positron-Emission Tomography; Purines; Pyrazoles; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2009
Current advances in vasodilator pharmacological stress perfusion imaging.
    Seminars in nuclear medicine, 2009, Volume: 39, Issue:3

    Topics: Adenosine; Adult; Contraindications; Coronary Artery Disease; Dipyridamole; Exercise Test; Female; Humans; Myocardial Perfusion Imaging; Purines; Pyrazoles; Radiopharmaceuticals; Vasodilator Agents

2009
[A novel way to induce coronary hyperaemia].
    Postepy higieny i medycyny doswiadczalnej (Online), 2013, Sep-10, Volume: 67

    Topics: Adenosine; Coronary Angiography; Coronary Stenosis; Fractional Flow Reserve, Myocardial; Humans; Hyperemia; Purines; Pyrazoles

2013
Magnetic resonance stress imaging of myocardial perfusion and wall motion.
    Journal of thoracic imaging, 2014, Volume: 29, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Cardiotonic Agents; Coronary Angiography; Dipyridamole; Exercise Test; Humans; Magnetic Resonance Imaging; Myocardial Perfusion Imaging; Purines; Pyrazoles; Vasodilator Agents

2014
Incidence of atrioventricular block with vasodilator stress SPECT: A meta-analysis.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019, Volume: 26, Issue:2

    Topics: Adenosine; Aged; Atrioventricular Block; Coronary Artery Disease; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Purines; Pyrazoles; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2019
P1 Receptor Agonists/Antagonists in Clinical Trials - Potential Drug Candidates of the Future.
    Current pharmaceutical design, 2019, Volume: 25, Issue:26

    Topics: Adenosine; Asthma; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Ligands; Neoplasms; Parkinson Disease; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrazoles; Receptors, Purinergic P1

2019
Practical instructions for using drugs in CT and MR cardiac imaging.
    La Radiologia medica, 2021, Volume: 126, Issue:3

    Topics: Adenosine; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Atropine; Calcium Channel Blockers; Cardiac Imaging Techniques; Computed Tomography Angiography; Contraindications, Drug; Coronary Angiography; Coronary Vessels; Dipyridamole; Dobutamine; Heart; Humans; Ivabradine; Magnetic Resonance Imaging; Nitroglycerin; Purines; Pyrazoles; Vasodilator Agents

2021

Trials

8 trial(s) available for regadenoson and adenosine

ArticleYear
Initial clinical experience with regadenoson, a novel selective A2A agonist for pharmacologic stress single-photon emission computed tomography myocardial perfusion imaging.
    Journal of the American College of Cardiology, 2005, Dec-06, Volume: 46, Issue:11

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Electrocardiography; Heart; Humans; Myocardial Ischemia; Organophosphorus Compounds; Organotechnetium Compounds; Pilot Projects; Purines; Pyrazoles; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tomography, Emission-Computed, Single-Photon

2005
Differences in heart rate response to adenosine and regadenoson in patients with and without diabetes mellitus.
    American heart journal, 2009, Volume: 157, Issue:4

    Topics: Adenosine; Adolescent; Adult; Aged; Coronary Disease; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Middle Aged; Organization and Administration; Prognosis; Purines; Pyrazoles; Vasodilator Agents; Young Adult

2009
Effects of age, gender, obesity, and diabetes on the efficacy and safety of the selective A2A agonist regadenoson versus adenosine in myocardial perfusion imaging integrated ADVANCE-MPI trial results.
    JACC. Cardiovascular imaging, 2008, Volume: 1, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adult; Age Factors; Aged; Aged, 80 and over; Body Mass Index; Coronary Circulation; Diabetes Complications; Double-Blind Method; Female; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Myocardial Ischemia; Myocardial Perfusion Imaging; Myocardium; Obesity; Patient Satisfaction; Predictive Value of Tests; Purines; Pyrazoles; Risk Assessment; Risk Factors; Sex Factors; Tomography, Emission-Computed, Single-Photon

2008
Regadenoson induces comparable left ventricular perfusion defects as adenosine: a quantitative analysis from the ADVANCE MPI 2 trial.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:8

    Topics: Adenosine; Coronary Artery Disease; Coronary Circulation; Double-Blind Method; Heart Ventricles; Humans; Infusions, Intravenous; Linear Models; Myocardial Ischemia; Myocardial Perfusion Imaging; Predictive Value of Tests; Prospective Studies; Purines; Pyrazoles; Severity of Illness Index; Stroke Volume; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents; Ventricular Dysfunction, Left

2009
The effect of obesity on regadenoson-induced myocardial hyperemia: a quantitative magnetic resonance imaging study.
    The international journal of cardiovascular imaging, 2012, Volume: 28, Issue:6

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Adult; Body Mass Index; Contrast Media; Coronary Circulation; Drug Dosage Calculations; Female; Humans; Hyperemia; Infusions, Intravenous; Injections, Intravenous; Magnetic Resonance Imaging, Cine; Male; Meglumine; Middle Aged; Myocardial Perfusion Imaging; Obesity; Organometallic Compounds; Predictive Value of Tests; Purines; Pyrazoles; Time Factors; Utah; Vasodilator Agents

2012
Regadenoson provides perfusion results comparable to adenosine in heterogeneous patient populations: a quantitative analysis from the ADVANCE MPI trials.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015, Volume: 22, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Coronary Artery Disease; Double-Blind Method; Female; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Male; Myocardial Perfusion Imaging; Purines; Pyrazoles; Reproducibility of Results; Sensitivity and Specificity; Stroke Volume; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents; Ventricular Dysfunction, Left

2015
Intravenous regadenoson with aminophylline reversal is safe and equivalent to intravenous adenosine infusion for fractional flow reserve measurements.
    Clinical cardiology, 2018, Volume: 41, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aminophylline; Cardiotonic Agents; Coronary Angiography; Coronary Stenosis; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Fractional Flow Reserve, Myocardial; Humans; Infusions, Intravenous; Male; Middle Aged; Purines; Pyrazoles; Reproducibility of Results; Retrospective Studies; Vasodilator Agents

2018
Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity.
    European heart journal. Cardiovascular Imaging, 2019, Jul-01, Volume: 20, Issue:7

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Caffeine; Cardiovascular Diseases; Coronary Circulation; Dipyridamole; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purines; Pyrazoles

2019

Other Studies

36 other study(ies) available for regadenoson and adenosine

ArticleYear
Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Amino Acids; Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Models, Molecular; Nucleosides; Phenethylamines; Protein Conformation; Radioligand Assay; Receptor, Adenosine A2A; Stereoisomerism; Structure-Activity Relationship; Thermodynamics

2012
Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Adenosine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Hydrazines; Ligands; Molecular Structure; Receptor, Adenosine A2A; Structure-Activity Relationship

2019
Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Adenosine; Animals; Antihypertensive Agents; Coronary Vessels; Corpus Striatum; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Male; PC12 Cells; Phenethylamines; Purinergic P1 Receptor Agonists; Purines; Pyrazoles; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Vasodilation; Vasodilator Agents

2001
Comparative profile of vasodilation by CVT-3146, a novel A2A receptor agonist, and adenosine in conscious dogs.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:1

    Topics: Adenosine; Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Vessels; Dogs; Heart; Heart Rate; Kidney; Mesenteric Arteries; Purinergic P1 Receptor Agonists; Purines; Pyrazoles; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilation; Vasodilator Agents

2003
New stress test agents reduce adverse effects.
    JAMA, 2008, May-14, Volume: 299, Issue:18

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Exercise Test; Humans; Purines; Pyrazoles; Vasodilator Agents

2008
Lessons from the development of new adenosine A2A receptor agonists.
    JACC. Cardiovascular imaging, 2008, Volume: 1, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Coronary Circulation; Humans; Image Interpretation, Computer-Assisted; Myocardial Ischemia; Myocardial Perfusion Imaging; Myocardium; Predictive Value of Tests; Purines; Pyrazoles; Reproducibility of Results; Tomography, Emission-Computed, Single-Photon

2008
Effects of adenosine and a selective A2A adenosine receptor agonist on hemodynamic and thallium-201 and technetium-99m-sestaMIBI biodistribution and kinetics.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:10

    Topics: Acute Disease; Adenosine; Adenosine A2 Receptor Agonists; Animals; Blood Flow Velocity; Chronic Disease; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Dogs; Hyperemia; Infusions, Intravenous; Injections, Intravenous; Metabolic Clearance Rate; Myocardial Perfusion Imaging; Myocardium; Predictive Value of Tests; Purines; Pyrazoles; Radiopharmaceuticals; Receptor, Adenosine A2A; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2009
Connectivity of radiotracers to vasodilators is thallium the missing link?
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:10

    Topics: Acute Disease; Adenosine; Adenosine A2 Receptor Agonists; Animals; Blood Flow Velocity; Chronic Disease; Coronary Circulation; Coronary Stenosis; Dogs; Humans; Hyperemia; Infusions, Intravenous; Injections, Intravenous; Metabolic Clearance Rate; Myocardial Perfusion Imaging; Myocardium; Predictive Value of Tests; Purines; Pyrazoles; Radiopharmaceuticals; Receptor, Adenosine A2A; Technetium Tc 99m Sestamibi; Thallium Radioisotopes; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2009
Regadenoson.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2010, Volume: 10, Issue:1

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Coronary Artery Disease; Coronary Circulation; Humans; Myocardial Perfusion Imaging; Purines; Pyrazoles

2010
Blunting of the heart rate response to adenosine and regadenoson in relation to hyperglycemia and the metabolic syndrome.
    The American journal of cardiology, 2010, Mar-15, Volume: 105, Issue:6

    Topics: Adenosine; Adolescent; Adult; Aged; Blood Pressure; Diabetes Mellitus; Female; Heart Rate; Humans; Hyperglycemia; Male; Metabolic Syndrome; Middle Aged; Myocardial Perfusion Imaging; Purines; Pyrazoles; Young Adult

2010
An example of the clinical selectivity of regadenoson for the A2a adenosine receptor.
    The American heart hospital journal, 2009,Winter, Volume: 7, Issue:2

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Aged; Biomarkers, Pharmacological; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Exercise Test; Humans; Male; Myocardial Perfusion Imaging; Purines; Pyrazoles; Receptor, Adenosine A2A; Vasodilator Agents

2009
Regadenoson is a safe and well-tolerated pharmacological stress agent for myocardial perfusion imaging in post-heart transplant patients.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2011, Volume: 18, Issue:4

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Female; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Purines; Pyrazoles; Retrospective Studies; Tomography, Emission-Computed, Single-Photon

2011
The crux of maximum hyperemia: the last remaining barrier for routine use of fractional flow reserve.
    JACC. Cardiovascular interventions, 2011, Volume: 4, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Coronary Stenosis; Coronary Vessels; Female; Fractional Flow Reserve, Myocardial; Humans; Male; Purines; Pyrazoles; Vasodilator Agents

2011
Comparison of the prognostic value of normal regadenoson with normal adenosine myocardial perfusion imaging with propensity score matching.
    JACC. Cardiovascular imaging, 2012, Volume: 5, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Cause of Death; Chi-Square Distribution; Female; Heart Diseases; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Myocardial Perfusion Imaging; Myocardial Revascularization; Predictive Value of Tests; Prognosis; Propensity Score; Proportional Hazards Models; Purines; Pyrazoles; Reference Values; Risk Factors; Stroke Volume; Time Factors; Vasodilator Agents; Ventricular Function, Left

2012
Comparing prognostic value of imaging agents and imaging techniques.
    JACC. Cardiovascular imaging, 2012, Volume: 5, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; Female; Heart Diseases; Humans; Male; Myocardial Perfusion Imaging; Purines; Pyrazoles; Vasodilator Agents

2012
Comparison of intravenous adenosine and intravenous regadenoson for the measurement of pressure-derived coronary fractional flow reserve.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2013, Feb-22, Volume: 8, Issue:10

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Blood Pressure; Female; Fractional Flow Reserve, Myocardial; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Purines; Pyrazoles

2013
Myocardial perfusion imaging laboratory efficiency with the use of regadenoson compared to adenosine and dipyridamole.
    Journal of medical economics, 2013, Volume: 16, Issue:4

    Topics: Adenosine; Coronary Artery Disease; Data Collection; Dipyridamole; Health Personnel; Humans; Myocardial Perfusion Imaging; Nuclear Medicine Department, Hospital; Purines; Pyrazoles; Receptor, Adenosine A2A; Time Factors; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

2013
Use of regadenoson for measurement of fractional flow reserve.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2014, Feb-15, Volume: 83, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Aged; Cardiac Catheterization; Coronary Angiography; Coronary Stenosis; Female; Fractional Flow Reserve, Myocardial; Hemodynamics; Humans; Hyperemia; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Predictive Value of Tests; Prognosis; Purines; Pyrazoles; Reproducibility of Results; Severity of Illness Index; Vasodilator Agents

2014
Exploratory use of cardiovascular magnetic resonance imaging in liver transplantation: a one-stop shop for preoperative cardiohepatic evaluation.
    Transplantation, 2013, Nov-15, Volume: 96, Issue:9

    Topics: Adenosine; Adult; Cardiovascular Diseases; Contrast Media; Coronary Angiography; Dobutamine; Feasibility Studies; Female; Humans; Liver Diseases; Liver Transplantation; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Preoperative Care; Purines; Pyrazoles

2013
Regadenoson and adenosine are equivalent vasodilators and are superior than dipyridamole- a study of first pass quantitative perfusion cardiovascular magnetic resonance.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2013, Sep-24, Volume: 15

    Topics: Adenosine; Coronary Circulation; Dipyridamole; Female; Healthy Volunteers; Heart Rate; Humans; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Myocardial Perfusion Imaging; Predictive Value of Tests; Purines; Pyrazoles; Vasodilation; Vasodilator Agents; Young Adult

2013
Is regadenoson an appropriate stressor for MPI in patients with left bundle branch block or pacemakers?
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013, Volume: 20, Issue:6

    Topics: Adenosine; Blood Pressure; Bundle-Branch Block; Exercise Test; Heart Rate; Humans; Myocardial Perfusion Imaging; Pacemaker, Artificial; Purines; Pyrazoles

2013
Regadenoson for FFR: time to say good-bye to adenosine?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2014, Feb-15, Volume: 83, Issue:3

    Topics: Adenosine; Adenosine A2 Receptor Agonists; Cardiac Catheterization; Coronary Stenosis; Female; Fractional Flow Reserve, Myocardial; Humans; Male; Purines; Pyrazoles; Vasodilator Agents

2014
Incremental value of pharmacological stress cardiac dual-energy CT over coronary CT angiography alone for the assessment of coronary artery disease in a high-risk population.
    AJR. American journal of roentgenology, 2014, Volume: 203, Issue:1

    Topics: Adenosine; Cardiac Catheterization; Cardiac-Gated Imaging Techniques; Contrast Media; Coronary Angiography; Coronary Artery Disease; Exercise Test; Female; Humans; Iopamidol; Male; Middle Aged; Prospective Studies; Purines; Pyrazoles; Radiation Dosage; Radiographic Image Interpretation, Computer-Assisted; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed

2014
Variability of fractional flow reserve according to the methods of hyperemia induction.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2015, Volume: 85, Issue:6

    Topics: Adenosine; Aged; Coronary Artery Disease; Coronary Circulation; Female; Fractional Flow Reserve, Myocardial; Hemodynamics; Humans; Hyperemia; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Middle Aged; Nicorandil; Purines; Pyrazoles; Radiography; Reproducibility of Results; Vasodilator Agents

2015
Splenic Switch-off: A Tool to Assess Stress Adequacy in Adenosine Perfusion Cardiac MR Imaging.
    Radiology, 2015, Volume: 276, Issue:3

    Topics: Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Imaging Techniques; Dobutamine; Exercise Test; Humans; Magnetic Resonance Angiography; Middle Aged; Perfusion; Purines; Pyrazoles; Retrospective Studies; Spleen; Young Adult

2015
Comparison of the prognostic value of regadenoson and adenosine myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015, Volume: 22, Issue:4

    Topics: Adenosine; Coronary Artery Disease; Death, Sudden, Cardiac; Exercise Test; Female; Humans; Incidence; Male; Middle Aged; Myocardial Perfusion Imaging; North Carolina; Prevalence; Prognosis; Purines; Pyrazoles; Reproducibility of Results; Retrospective Studies; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Vasodilator Agents

2015
Vasodilator stress with adenosine and the gender preponderance for tolerability and manifestation of adverse symptoms: Is there a physiological basis?
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015, Volume: 22, Issue:5

    Topics: Adenosine; Cardiology; Exercise Test; Female; Humans; Image Processing, Computer-Assisted; Male; Nuclear Medicine; Purines; Pyrazoles; Sex Factors; Vasodilator Agents

2015
Comparison of the Safety of Adenosine and Regadenoson in Patients Undergoing Outpatient Cardiac Stress Testing.
    Pharmacotherapy, 2015, Volume: 35, Issue:12

    Topics: Adenosine; Cohort Studies; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Purines; Pyrazoles; Retrospective Studies

2015
Role of Perfusion at Rest in the Diagnosis of Myocardial Infarction Using Vasodilator Stress Cardiovascular Magnetic Resonance.
    The American journal of cardiology, 2016, Apr-01, Volume: 117, Issue:7

    Topics: Adenosine; Aged; Chronic Disease; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardial Perfusion Imaging; Purines; Pyrazoles; Rest; Retrospective Studies; Vasodilator Agents

2016
Impact of pharmacological stress agent on patient motion during rubidium-82 myocardial perfusion PET/CT.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018, Volume: 25, Issue:4

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Coronary Circulation; Female; Humans; Male; Middle Aged; Motion; Myocardial Perfusion Imaging; Positron Emission Tomography Computed Tomography; Purines; Pyrazoles; Respiration; Retrospective Studies; Rubidium Radioisotopes

2018
Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping.
    The international journal of cardiovascular imaging, 2017, Volume: 33, Issue:11

    Topics: Adenosine; Aged; Caffeine; Coffee; Coronary Artery Disease; Coronary Circulation; Female; Humans; Hyperemia; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Perfusion Imaging; Predictive Value of Tests; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrazoles; Reproducibility of Results; Time Factors; Vasodilator Agents

2017
Effects of adenosine and regadenoson on hemodynamics measured using cardiovascular magnetic resonance imaging.
    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017, Dec-04, Volume: 19, Issue:1

    Topics: Adenosine; Adult; Coronary Circulation; Female; Healthy Volunteers; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Magnetic Resonance Imaging, Cine; Male; Predictive Value of Tests; Prospective Studies; Purines; Pyrazoles; Stroke Volume; Time Factors; Vasodilator Agents; Ventricular Function, Left; Ventricular Function, Right

2017
Safety of regadenoson positron emission tomography stress testing in orthotopic heart transplant patients.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020, Volume: 27, Issue:3

    Topics: Adenosine; Aged; Blood Pressure; Electrocardiography; Exercise Test; Female; Heart Transplantation; Hemodynamics; Humans; Male; Middle Aged; Myocardial Perfusion Imaging; Patient Safety; Positron-Emission Tomography; Purines; Pyrazoles; Retrospective Studies; Risk Factors; Stress, Mechanical; Transplant Recipients; Vascular Diseases

2020
Safety and tolerability of regadenoson in comparison with adenosine stress cardiovascular magnetic resonance: Data from a multicentre prospective registry.
    The international journal of cardiovascular imaging, 2022, Volume: 38, Issue:1

    Topics: Adenosine; Humans; Magnetic Resonance Spectroscopy; Myocardial Perfusion Imaging; Predictive Value of Tests; Purines; Pyrazoles; Registries; Vasodilator Agents

2022
Quantitative myocardial perfusion response to adenosine and regadenoson in patients with suspected coronary artery disease.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:1

    Topics: Adenosine; Arteries; Coronary Artery Disease; Coronary Circulation; Humans; Hyperemia; Myocardial Perfusion Imaging; Perfusion; Positron-Emission Tomography; Purines; Pyrazoles; Water

2022
Left ventricular ejection fraction, myocardial blood flow and hemodynamic variables in adenosine and regadenoson vasodilator 82-Rubidium PET.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:3

    Topics: Adenosine; Coronary Artery Disease; Coronary Circulation; Hemodynamics; Humans; Myocardial Perfusion Imaging; Positron-Emission Tomography; Purines; Pyrazoles; Rubidium; Stroke Volume; Vasodilator Agents; Ventricular Function, Left

2022