regadenoson has been researched along with adenosine-5'-(n-ethylcarboxamide) in 4 studies
| Studies (regadenoson) | Trials (regadenoson) | Recent Studies (post-2010) (regadenoson) | Studies (adenosine-5'-(n-ethylcarboxamide)) | Trials (adenosine-5'-(n-ethylcarboxamide)) | Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide)) |
|---|---|---|---|---|---|
| 321 | 53 | 264 | 1,333 | 4 | 133 |
| Protein | Taxonomy | regadenoson (IC50) | adenosine-5'-(n-ethylcarboxamide) (IC50) |
|---|---|---|---|
| Adenosine receptor A3 | Homo sapiens (human) | 0.0097 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.037 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.4498 | |
| Adenosine receptor A2a | Homo sapiens (human) | 0.0336 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.0175 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0007 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0513 | |
| Adenosine receptor A1 | Gallus gallus (chicken) | 0.017 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deflorian, F; Gao, ZG; Jacobson, KA; Katritch, V; Kumar, TS; Phan, K; Stevens, RC; Wu, H; Xu, F | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
| Aghazadeh Tabrizi, M; Baraldi, PG; Baraldi, S; Borea, PA; Bruno, A; Cosconati, S; Novellino, E; Preti, D; Ravani, A; Romagnoli, R; Saponaro, G; Varani, K; Vincenzi, F | 1 |
| Fan, S; Li, S; Xie, F; Zhang, M; Zhong, W; Zhou, X | 1 |
1 review(s) available for regadenoson and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
3 other study(ies) available for regadenoson and adenosine-5'-(n-ethylcarboxamide)
| Article | Year |
|---|---|
Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Amino Acids; Animals; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; Ligands; Models, Molecular; Nucleosides; Phenethylamines; Protein Conformation; Radioligand Assay; Receptor, Adenosine A2A; Stereoisomerism; Structure-Activity Relationship; Thermodynamics | 2012 |
Design, synthesis, and biological evaluation of novel 2-((2-(4-(substituted)phenylpiperazin-1-yl)ethyl)amino)-5'-N-ethylcarboxamidoadenosines as potent and selective agonists of the A2A adenosine receptor.
Topics: Adenosine A2 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Chemistry Techniques, Synthetic; CHO Cells; Cricetulus; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; Humans; Molecular Docking Simulation; Receptor, Adenosine A2A; Structure-Activity Relationship | 2015 |
Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A
Topics: Adenosine; Cyclic AMP; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Hydrazines; Ligands; Molecular Structure; Receptor, Adenosine A2A; Structure-Activity Relationship | 2019 |