Page last updated: 2024-09-03

reboxetine and olanzapine

reboxetine has been researched along with olanzapine in 11 studies

Compound Research Comparison

Studies
(reboxetine)
Trials
(reboxetine)
Recent Studies (post-2010)
(reboxetine)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
6261931846,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomyreboxetine (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Arnone, D; Hansen, L; Kerr, JS1
Faragian, S; Fuchs, C; Isaacs, I; Poyurovsky, M; Schneidman, M; Weizman, A; Weizman, R1
Faragian, S; Fuchs, C; Gil-Ad, I; Levi, A; Maayan, R; Pashinian, A; Poyurovsky, M1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Faragian, S; Fuchs, C; Pashinian, A; Poyurovsky, M1
Björkholm, C; Jardemark, K; Malmerfelt, A; Marcus, MM; Svensson, TH1
Fisar, Z; Hroudová, J; Raboch, J1
Fuchs, C; Levi, A; Pashinian, A; Poyurovsky, M; Weizman, A; Weizman, R1
Amrami-Weizman, A; Fuchs, C; Gil-Ad, I; Kotler, M; Maayan, R; Pashinian, A; Poyurovsky, M1
Bernardo, M; Caballero, M; Corripio, I; Felipe, AE; Fernandez de Corres, B; González Piqueras, JC; Huerta, R; Ibáñez, A; Iniesta, R; López-Carrilero, R; Oliveira, C; Roca, M; Rodriguez-Jimenez, R; Sindreu, SD; Usall, J1
Koziorowski, M; Mytych, J; Sołek, P; Tabęcka-Łonczyńska, A1

Trials

6 trial(s) available for reboxetine and olanzapine

ArticleYear
Attenuation of olanzapine-induced weight gain with reboxetine in patients with schizophrenia: a double-blind, placebo-controlled study.
    The American journal of psychiatry, 2003, Volume: 160, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Benzodiazepines; Body Mass Index; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Morpholines; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Reboxetine; Schizophrenia; Treatment Outcome; Weight Gain

2003
Attenuating effect of reboxetine on appetite and weight gain in olanzapine-treated schizophrenia patients: a double-blind placebo-controlled study.
    Psychopharmacology, 2007, Volume: 192, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Appetite; Benzodiazepines; Body Mass Index; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines; Olanzapine; Reboxetine; Schizophrenia; Weight Gain

2007
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
Reducing antipsychotic-induced weight gain in schizophrenia: a double-blind placebo-controlled study of reboxetine-betahistine combination.
    Psychopharmacology, 2013, Volume: 226, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Benzodiazepines; Betahistine; Double-Blind Method; Female; Histamine Agonists; Humans; Male; Middle Aged; Morpholines; Olanzapine; Reboxetine; Schizophrenia; Treatment Outcome; Weight Gain; Young Adult

2013
The effect of reboxetine co-administration with olanzapine on metabolic and endocrine profile in schizophrenia patients.
    Psychopharmacology, 2013, Volume: 230, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Morpholines; Olanzapine; Reboxetine; Schizophrenia; Weight Gain; Young Adult

2013
Double-blind, placebo-controlled study of the efficacy of reboxetine and citalopram as adjuncts to atypical antipsychotics for negative symptoms of schizophrenia.
    The Journal of clinical psychiatry, 2014, Volume: 75, Issue:6

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Citalopram; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Olanzapine; Psychiatric Status Rating Scales; Reboxetine; Risperidone; Schizophrenia; Schizophrenic Psychology

2014

Other Studies

5 other study(ies) available for reboxetine and olanzapine

ArticleYear
Acute dystonic reaction in an elderly patient with mood disorder after titration of paroxetine: possible mechanisms and implications for clinical care.
    Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:4

    Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dystonic Disorders; Electroconvulsive Therapy; Humans; Male; Morpholines; Olanzapine; Paroxetine; Pirenzepine; Reboxetine

2002
Effect of the selective norepinephrine reuptake inhibitor reboxetine on cognitive dysfunction in schizophrenia patients: an add-on, double-blind placebo-controlled study.
    The Israel journal of psychiatry and related sciences, 2009, Volume: 46, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Adult; Antipsychotic Agents; Benzodiazepines; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morpholines; Neuropsychological Tests; Olanzapine; Psychiatric Status Rating Scales; Psychotic Disorders; Reboxetine; Schizophrenia; Schizophrenic Psychology; Young Adult

2009
Reboxetine enhances the olanzapine-induced antipsychotic-like effect, cortical dopamine outflow and NMDA receptor-mediated transmission.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:9

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Benzodiazepines; Cerebral Cortex; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Freezing Reaction, Cataleptic; In Vitro Techniques; Male; Membrane Potentials; Microdialysis; Morpholines; N-Methylaspartate; Olanzapine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reboxetine; Receptors, N-Methyl-D-Aspartate

2010
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:5

    Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride

2010
Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects.
    International journal of molecular sciences, 2021, Nov-01, Volume: 22, Issue:21

    Topics: Amitriptyline; Animals; Antidepressive Agents; Antipsychotic Agents; Cell Line; Escitalopram; Fluoxetine; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Imipramine; Male; Mice; Micronuclei, Chromosome-Defective; Mirtazapine; Models, Biological; Olanzapine; Organ Specificity; Reboxetine; Reproduction; Signal Transduction; Spermatogenesis; Telomeric Repeat Binding Protein 1; Telomeric Repeat Binding Protein 2; Time Factors; Venlafaxine Hydrochloride

2021