Page last updated: 2024-09-03

reboxetine and mianserin

reboxetine has been researched along with mianserin in 23 studies

Compound Research Comparison

Studies
(reboxetine)
Trials
(reboxetine)
Recent Studies (post-2010)
(reboxetine)
Studies
(mianserin)
Trials
(mianserin)
Recent Studies (post-2010) (mianserin)
6261931842,624539488

Protein Interaction Comparison

ProteinTaxonomyreboxetine (IC50)mianserin (IC50)
5-hydroxytryptamine receptor 3EHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0012
5-hydroxytryptamine receptor 3BHomo sapiens (human)1.4125
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.163
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.078
Muscarinic acetylcholine receptor M4Homo sapiens (human)2.066
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.3981
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)1.9
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.32
Alpha-2A adrenergic receptorHomo sapiens (human)0.0213
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.423
D(2) dopamine receptorHomo sapiens (human)7.0795
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.38
Alpha-2B adrenergic receptorHomo sapiens (human)0.026
Alpha-2C adrenergic receptorHomo sapiens (human)0.0661
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.872
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.21
Muscarinic acetylcholine receptor M3Homo sapiens (human)1.405
D(1A) dopamine receptorHomo sapiens (human)0.543
D(4) dopamine receptorHomo sapiens (human)3.3113
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.21
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.21
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.38
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.163
5-hydroxytryptamine receptor 3AMus musculus (house mouse)1.4125
Histamine H2 receptorHomo sapiens (human)1.008
Alpha-1D adrenergic receptorHomo sapiens (human)0.083
Endothelin-1 receptorHomo sapiens (human)0.1148
5-hydroxytryptamine receptor 1DHomo sapiens (human)0.3802
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.011
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0043
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.872
Sodium-dependent serotonin transporterHomo sapiens (human)2.068
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)2.9
5-hydroxytryptamine receptor 7Homo sapiens (human)0.1148
Alpha-1A adrenergic receptorHomo sapiens (human)0.4074
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.21
Histamine H1 receptorHomo sapiens (human)0.0024
D(3) dopamine receptorHomo sapiens (human)3.8905
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0073
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.19
5-hydroxytryptamine receptor 3AHomo sapiens (human)1.4125
Histamine H2 receptorCavia porcellus (domestic guinea pig)0.88
5-hydroxytryptamine receptor 6Homo sapiens (human)0.085
D(2) dopamine receptorRattus norvegicus (Norway rat)3.5481
5-hydroxytryptamine receptor 3DHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 3CHomo sapiens (human)1.4125
5-hydroxytryptamine receptor 3BMus musculus (house mouse)1.4125
TransporterRattus norvegicus (Norway rat)0.022

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's17 (73.91)29.6817
2010's4 (17.39)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Gorman, JM; Sullivan, G1
Fava, M1
Kent, JM1
Cohen, NL; Kennedy, SH; Lam, RW; Wan, DD1
Aguglia, E; Amore, M; Delgado, PL; Gastpar, M; Hawley, C; Hirschfeld, RM; Kasper, S; Linden, M; Massana, J; Mendlewicz, J; Möller, HJ; Montgomery, SA; Nemeroff, CB; Saiz, J; Such, P; Torta, R; Versiani, M1
Elger, CE; Falkai, P; Kühn, KU; Maier, W; Quednow, BB; Thiel, M1
Baghai, T; Laakmann, G; Schüle, C1
Di Chiara, G; Frau, R; Valentini, V1
Alamo, C; López-Muñoz, F; Rubio, G; San, L1
Almási, J; Rihmer, Z1
Baumann, P; Engel, R; Fähndrich, E; Greil, W; Hippius, H; Horvath, A; Mayland, G; Rüther, E; Schmidt, LG; Zullino, D1
Amann, B; Hegerl, U; Juckel, G; Mergl, R; Mulert, C; Padberg, F; Pogarell, O; Sterr, A1
Baghai, TC; Buechs, R; Eser, D; Jordan, M; Rupprecht, R; Schüle, C; Zwanzger, P1
Bajbouj, M; Danker-Hopfe, H; Gallinat, J; Hellen, F; Lang, UE; Lisanby, SH; Neu, P; Vesper, J1
Källén, B; Lennestål, R1
Gallwitz, T; Kirch, MH; Messer, T; Rottach, KG; Schaner, BM; Teufel, LM; Zivotofsky, AZ1
Brunnauer, A; David, I; Fric, M; Hermisson, I; Laux, G; Möller, HJ1
Bellodi, L; Calati, R; Chiesa, A; De Ronchi, D; Perna, G; Serretti, A1
Fisar, Z; Hroudová, J; Raboch, J1
Artigas, F; Bortolozzi, A; Castañé, A; Masana, M; Santana, N1
Callado, LF; Díez-Alarcia, R; González-Maeso, J; Meana, JJ; Miranda-Azpiazu, P; Morentin, B; Muguruza, C1
Chmielarz, P; Chorązka, K; Kowalska, M; Kuśmierczyk, J; Nalepa, I; Rafa-Zabłocka, K; Satała, G1
Keidan, L; Pick, CG; Schreiber, S1

Reviews

7 review(s) available for reboxetine and mianserin

ArticleYear
Noradrenergic approaches to antidepressant therapy.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 1

    Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Depressive Disorder; Humans; Mianserin; Mirtazapine; Morpholines; Norepinephrine; Reboxetine; Receptors, Adrenergic; Selective Serotonin Reuptake Inhibitors

2000
New approaches to the treatment of refractory depression.
    The Journal of clinical psychiatry, 2000, Volume: 61 Suppl 1

    Topics: Antidepressive Agents; Buspirone; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Pindolol; Piperazines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thyroxine; Triazoles; Triiodothyronine

2000
SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression.
    Lancet (London, England), 2000, Mar-11, Volume: 355, Issue:9207

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Cyclohexanols; Depressive Disorder; Humans; Mianserin; Mirtazapine; Morpholines; Piperazines; Reboxetine; Structure-Activity Relationship; Treatment Outcome; Triazoles; Venlafaxine Hydrochloride

2000
Combining antidepressants for treatment-resistant depression: a review.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:8

    Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Cyclohexanols; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combination; Humans; Mianserin; Monoamine Oxidase Inhibitors; Morpholines; Psychiatric Status Rating Scales; Reboxetine; Research Design; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Venlafaxine Hydrochloride

2002
Partial response and nonresponse to antidepressant therapy: current approaches and treatment options.
    The Journal of clinical psychiatry, 2002, Volume: 63, Issue:9

    Topics: Antidepressive Agents; Congresses as Topic; Cyclopropanes; Decision Trees; Depressive Disorder; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Evidence-Based Medicine; Humans; Lithium; Mianserin; Milnacipran; Mirtazapine; Morpholines; Practice Patterns, Physicians'; Psychiatric Status Rating Scales; Reboxetine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome

2002
[Review of antidepressants from the TCAs to the third generation drugs].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2004, Volume: 6, Issue:4

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Cyclohexanols; Cyclopropanes; Depressive Disorder, Major; Drug Combinations; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Monoamine Oxidase Inhibitors; Morpholines; Piperazines; Pyrimidines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Thiophenes; Trazodone; Triazoles; Venlafaxine Hydrochloride

2004
Novel antidepressants and panic disorder: evidence beyond current guidelines.
    Neuropsychobiology, 2011, Volume: 63, Issue:1

    Topics: Antidepressive Agents; Clinical Trials as Topic; Cyclopropanes; Duloxetine Hydrochloride; Humans; Mianserin; Milnacipran; Mirtazapine; Morpholines; Panic Disorder; Practice Guidelines as Topic; Reboxetine; Thiophenes

2011

Trials

6 trial(s) available for reboxetine and mianserin

ArticleYear
Antidepressive treatment in patients with temporal lobe epilepsy and major depression: a prospective study with three different antidepressants.
    Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Antidepressive Agents; Chi-Square Distribution; Citalopram; Demography; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Interactions; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Patient Dropouts; Personality Inventory; Prospective Studies; Psychiatric Status Rating Scales; Reboxetine; Time Factors

2003
Mirtazapine decreases stimulatory effects of reboxetine on cortisol, adrenocorticotropin and prolactin secretion in healthy male subjects.
    Neuroendocrinology, 2004, Volume: 79, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Adrenocorticotropic Hormone; Adult; Area Under Curve; Drug Combinations; Drug Interactions; Growth Hormone; Humans; Hydrocortisone; Male; Mianserin; Mirtazapine; Morpholines; Prolactin; Reboxetine; Time Factors

2004
Reboxetine adjunct for partial or nonresponders to antidepressant treatment.
    Journal of affective disorders, 2004, Volume: 81, Issue:1

    Topics: Adult; Antidepressive Agents; Cyclohexanols; Depressive Disorder; Depressive Disorder, Major; Drug Resistance; Drug Therapy, Combination; Dysthymic Disorder; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Personality Inventory; Prospective Studies; Reboxetine; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Venlafaxine Hydrochloride

2004
Time course of hypothalamic-pituitary-adrenocortical axis activity during treatment with reboxetine and mirtazapine in depressed patients.
    Psychopharmacology, 2006, Volume: 186, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Antidepressive Agents; Corticotropin-Releasing Hormone; Depressive Disorder, Major; Dexamethasone; Female; Glucocorticoids; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Pituitary-Adrenal System; Psychiatric Status Rating Scales; Reboxetine; Time Factors

2006
Motor cortex excitability after vagus nerve stimulation in major depression.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:2

    Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Therapy, Combination; Electric Stimulation; Female; Humans; Lamotrigine; Lithium Carbonate; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Motor Cortex; Neural Conduction; Neural Inhibition; Olanzapine; Paroxetine; Psychiatric Status Rating Scales; Reboxetine; Tranylcypromine; Triazines; Vagus Nerve; Valproic Acid

2007
The impact of reboxetine and mirtazapine on driving simulator performance and psychomotor function in depressed patients.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:12

    Topics: Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Attention; Automobile Driving; Computer Simulation; Depressive Disorder; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Personality Inventory; Psychomotor Performance; Reaction Time; Reboxetine

2008

Other Studies

10 other study(ies) available for reboxetine and mianserin

ArticleYear
Noradrenaline transporter blockers raise extracellular dopamine in medial prefrontal but not parietal and occipital cortex: differences with mianserin and clozapine.
    Journal of neurochemistry, 2004, Volume: 88, Issue:4

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Clozapine; Desipramine; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Extracellular Space; Male; Mianserin; Microdialysis; Morpholines; Neural Pathways; Norepinephrine Plasma Membrane Transport Proteins; Oxidopamine; Piperazines; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Antagonists; Symporters; Time Factors

2004
Prescribing practices in German and Swiss psychiatric university and in non-university hospitals: national differences.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Community Mental Health Centers; Drug Prescriptions; Drug Utilization; Female; Germany; Hospitals, Psychiatric; Humans; Mental Disorders; Mianserin; Middle Aged; Mirtazapine; Morpholines; Piperazines; Practice Patterns, Physicians'; Reboxetine; Rural Health Services; Selective Serotonin Reuptake Inhibitors; Sex Factors; Switzerland; Triazoles; Urban Health Services

2005
Electroencephalographic abnormalities associated with antidepressant treatment: a comparison of mirtazapine, venlafaxine, citalopram, reboxetine, and amitriptyline.
    The Journal of clinical psychiatry, 2006, Volume: 67, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Cerebral Cortex; Citalopram; Cyclohexanols; Electroencephalography; Epilepsy; Female; Humans; Male; Mental Disorders; Mianserin; Middle Aged; Mirtazapine; Morpholines; Reboxetine; Venlafaxine Hydrochloride

2006
Delivery outcome in relation to maternal use of some recently introduced antidepressants.
    Journal of clinical psychopharmacology, 2007, Volume: 27, Issue:6

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adrenergic Uptake Inhibitors; Antidepressive Agents; Birth Weight; Cyclohexanols; Databases, Factual; Delivery, Obstetric; Female; Gestational Age; Humans; Infant Mortality; Infant, Newborn; Mianserin; Mirtazapine; Morpholines; Pregnancy; Pregnancy Trimester, First; Prenatal Exposure Delayed Effects; Reboxetine; Registries; Selective Serotonin Reuptake Inhibitors; Smoking; Sweden; Venlafaxine Hydrochloride

2007
Restless legs syndrome as side effect of second generation antidepressants.
    Journal of psychiatric research, 2008, Volume: 43, Issue:1

    Topics: Acute Disease; Adult; Antidepressive Agents; Citalopram; Depressive Disorder; Depressive Disorder, Major; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Prospective Studies; Reboxetine; Restless Legs Syndrome; Selective Serotonin Reuptake Inhibitors

2008
Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:5

    Topics: Affect; Amitriptyline; Animals; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Cerebral Cortex; Citalopram; Clorgyline; Cocaine; Cyclohexanols; Desipramine; Fluoxetine; Imipramine; In Vitro Techniques; Iproniazid; Lithium; Mianserin; Mirtazapine; Mitochondria; Moclobemide; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morpholines; Olanzapine; Pargyline; Reboxetine; Swine; Thiazepines; Valproic Acid; Venlafaxine Hydrochloride

2010
Noradrenergic antidepressants increase cortical dopamine: potential use in augmentation strategies.
    Neuropharmacology, 2012, Volume: 63, Issue:4

    Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Brain-Derived Neurotrophic Factor; Depression; Dopamine; Drug Synergism; Drug Therapy, Combination; Extracellular Fluid; Gene Expression Regulation; Male; Mianserin; Mirtazapine; Morpholines; Organ Specificity; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reboxetine; RNA, Messenger

2012
Evaluation of 5-HT2A and mGlu2/3 receptors in postmortem prefrontal cortex of subjects with major depressive disorder: effect of antidepressant treatment.
    Neuropharmacology, 2014, Volume: 86

    Topics: Amino Acids; Animals; Antidepressive Agents; Citalopram; Depressive Disorder, Major; Down-Regulation; Female; Humans; Ketanserin; Male; Mianserin; Middle Aged; Mirtazapine; Morpholines; Prefrontal Cortex; Radioligand Assay; Rats, Sprague-Dawley; Reboxetine; Receptor, Serotonin, 5-HT2A; Receptors, Metabotropic Glutamate; RNA, Messenger; Tritium; Xanthenes

2014
Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro.
    International journal of molecular sciences, 2021, May-01, Volume: 22, Issue:9

    Topics: Animals; Antidepressive Agents; Citalopram; Depression; Desipramine; Fluoxetine; Gene Expression Regulation; Humans; Imipramine; Mianserin; Mice; PC12 Cells; Rats; Reboxetine; Receptors, Adrenergic, alpha-1; Signal Transduction

2021
Treatment-Resistant Depression (TRD): Is the Opioid System Involved?
    International journal of molecular sciences, 2023, Jul-06, Volume: 24, Issue:13

    Topics: Analgesics, Opioid; Animals; Antidepressive Agents; Depression; Dose-Response Relationship, Drug; Fluoxetine; Fluvoxamine; Mianserin; Mice; Mirtazapine; Moclobemide; Naloxone; Reboxetine; Trazodone; Venlafaxine Hydrochloride

2023