Page last updated: 2024-09-03

reboxetine and metoprolol

reboxetine has been researched along with metoprolol in 2 studies

Compound Research Comparison

Studies (reboxetine)	Trials (reboxetine)	Recent Studies (post-2010) (reboxetine)	Studies (metoprolol)	Trials (metoprolol)	Recent Studies (post-2010) (metoprolol)
626	193	184	5,821	1,743	1,304

Protein Interaction Comparison

Protein	Taxonomy	metoprolol (IC50)
Beta-2 adrenergic receptor	Homo sapiens (human)	2.573
Beta-1 adrenergic receptor	Homo sapiens (human)	0.176
Cytochrome P450 2C9	Homo sapiens (human)	4.87
Cytochrome P450 2J2	Homo sapiens (human)	4.87

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gutzki, FM; Jordan, J; Kayacelebi, AA; Schroeder, C; Stichtenoth, DO; Suchy, MT; Tank, J; Tsikas, D; Zoerner, AA	1
Großhennig, A; Heusser, K; Jordan, J; Luft, FC; May, M; Mehling, H; Schroeder, C; Sweep, FC; Tank, J; Wenzel, D; Zoerner, AA	1

Trials

1 trial(s) available for reboxetine and metoprolol

Article	Year
Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study. Clinical pharmacology and therapeutics, 2014, Volume: 95, Issue:6 Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Benzazepines; Blood Pressure; Cardiotonic Agents; Cross-Over Studies; Double-Blind Method; Endpoint Determination; Heart; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Metoprolol; Morpholines; Muscle Proteins; Norepinephrine; Orthostatic Intolerance; Pacemaker, Artificial; Potassium Channels; Reboxetine; Stroke Volume; Sympathetic Nervous System; Syncope; Young Adult	2014

Article

Year

Pacemaker current inhibition in experimental human cardiac sympathetic activation: a double-blind, randomized, crossover study.

Clinical pharmacology and therapeutics, 2014, Volume: 95, Issue:6

Topics: Adolescent; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Benzazepines; Blood Pressure; Cardiotonic Agents; Cross-Over Studies; Double-Blind Method; Endpoint Determination; Heart; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Metoprolol; Morpholines; Muscle Proteins; Norepinephrine; Orthostatic Intolerance; Pacemaker, Artificial; Potassium Channels; Reboxetine; Stroke Volume; Sympathetic Nervous System; Syncope; Young Adult

2014

Other Studies

1 other study(ies) available for reboxetine and metoprolol

Article	Year
A validated, rapid UPLC-MS/MS method for simultaneous ivabradine, reboxetine, and metoprolol analysis in human plasma and its application to clinical trial samples. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, May-15, Volume: 927 Topics: Benzazepines; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Drug Stability; Humans; Ivabradine; Linear Models; Male; Metoprolol; Morpholines; Randomized Controlled Trials as Topic; Reboxetine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry	2013

Article

Year

A validated, rapid UPLC-MS/MS method for simultaneous ivabradine, reboxetine, and metoprolol analysis in human plasma and its application to clinical trial samples.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2013, May-15, Volume: 927

Topics: Benzazepines; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Drug Stability; Humans; Ivabradine; Linear Models; Male; Metoprolol; Morpholines; Randomized Controlled Trials as Topic; Reboxetine; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry

2013