Page last updated: 2024-09-03

reboxetine and maprotiline

reboxetine has been researched along with maprotiline in 3 studies

Compound Research Comparison

Studies
(reboxetine)
Trials
(reboxetine)
Recent Studies (post-2010)
(reboxetine)
Studies
(maprotiline)
Trials
(maprotiline)
Recent Studies (post-2010) (maprotiline)
62619318493321159

Protein Interaction Comparison

ProteinTaxonomyreboxetine (IC50)maprotiline (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.078
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.03
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.927
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.413
Cytochrome P450 3A4Homo sapiens (human)4.322
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.16
Alpha-2A adrenergic receptorHomo sapiens (human)1.824
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.593
D(2) dopamine receptorHomo sapiens (human)3.463
Alpha-2B adrenergic receptorHomo sapiens (human)0.292
Alpha-2C adrenergic receptorHomo sapiens (human)3.044
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.473
D(1A) dopamine receptorHomo sapiens (human)0.373
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.03
Histamine H2 receptorHomo sapiens (human)0.4
Alpha-1D adrenergic receptorHomo sapiens (human)0.397
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.064
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.078
Histamine H1 receptorHomo sapiens (human)0.0088
D(3) dopamine receptorHomo sapiens (human)0.645
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.336
5-hydroxytryptamine receptor 6Homo sapiens (human)0.892
Voltage-dependent N-type calcium channel subunit alpha-1BHomo sapiens (human)10
Sodium-dependent dopamine transporter Homo sapiens (human)2.91

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertolín-Guillén, JM; Climent-Díaz, B; Navarré-Gimeno, A1
Benveniste, H; Carter, P; Ding, YS; Lin, KS; Logan, J1
Li, B; Li, X; Li, Y; Wang, P; Xue, W; Yang, F; Yao, X; Zheng, G; Zhu, F1

Other Studies

3 other study(ies) available for reboxetine and maprotiline

ArticleYear
Serotonin syndrome due to association of venlafaxine, maprotiline and reboxetine.
    European psychiatry : the journal of the Association of European Psychiatrists, 2004, Volume: 19, Issue:7

    Topics: Cyclohexanols; Depressive Disorder; Emergency Medical Services; Humans; Male; Maprotiline; Middle Aged; Morpholines; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Venlafaxine Hydrochloride

2004
Comparative evaluation of positron emission tomography radiotracers for imaging the norepinephrine transporter: (S,S) and (R,R) enantiomers of reboxetine analogs ([11C]methylreboxetine, 3-Cl-[11C]methylreboxetine and [18F]fluororeboxetine), (R)-[11C]nisox
    Journal of neurochemistry, 2005, Volume: 94, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Autoradiography; Benzopyrans; Binding, Competitive; Brain; Brain Chemistry; Brain Mapping; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Evaluation Studies as Topic; Fluorine Radioisotopes; Fluoxetine; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Maprotiline; Mice; Morpholines; Nordefrin; Norepinephrine Plasma Membrane Transport Proteins; Papio; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Reboxetine; Symporters; Time Factors; Tissue Distribution

2005
Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study.
    Scientific reports, 2016, 05-27, Volume: 6

    Topics: Amino Acid Motifs; Antipsychotic Agents; Atomoxetine Hydrochloride; Binding Sites; Humans; Maprotiline; Molecular Docking Simulation; Molecular Dynamics Simulation; Morpholines; Neurotransmitter Uptake Inhibitors; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Reboxetine; Stereoisomerism; Structural Homology, Protein; Thermodynamics; Viloxazine

2016