Page last updated: 2024-09-03

reboxetine and 8-hydroxy-2-(di-n-propylamino)tetralin

reboxetine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 2 studies

Compound Research Comparison

Studies (reboxetine)	Trials (reboxetine)	Recent Studies (post-2010) (reboxetine)	Studies (8-hydroxy-2-(di-n-propylamino)tetralin)	Trials (8-hydroxy-2-(di-n-propylamino)tetralin)	Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
626	193	184	3,530	7	389

Protein Interaction Comparison

Protein	Taxonomy	8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	0.0012
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	0.0032
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Bos taurus (cattle)	0.8
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.81
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	2.8959
Lysosomal alpha-glucosidase	Bos taurus (cattle)	0.0021

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Connor, TJ; Dredge, K; Harkin, A; Kelly, JP; Leonard, BE; McNamara, M; Redmond, A	1
Blier, P; Szabo, ST	1

Other Studies

2 other study(ies) available for reboxetine and 8-hydroxy-2-(di-n-propylamino)tetralin

Article	Year
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression. European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics; Animals; Antidepressive Agents; Body Temperature; Clonidine; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Morpholines; Motor Activity; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Receptor Agonists; Sertraline; Swimming	1999
Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons. The European journal of neuroscience, 2001, Volume: 13, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Clonidine; Depression; Dose-Response Relationship, Drug; Indophenol; Locus Coeruleus; Male; Morpholines; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin; Serotonin Receptor Agonists	2001

Article

Year

Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.

European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics; Animals; Antidepressive Agents; Body Temperature; Clonidine; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Morpholines; Motor Activity; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Receptor Agonists; Sertraline; Swimming

1999

Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons.

The European journal of neuroscience, 2001, Volume: 13, Issue:11

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Clonidine; Depression; Dose-Response Relationship, Drug; Indophenol; Locus Coeruleus; Male; Morpholines; Norepinephrine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin; Serotonin Receptor Agonists

2001