Compounds > rc 3095
Page last updated: 2024-09-03

rc 3095 and gastrins

rc 3095 has been researched along with gastrins in 13 studies

Compound Research Comparison

Studies
(rc 3095)		Trials
(rc 3095)		Recent Studies (post-2010)
(rc 3095)		Studies
(gastrins)		Trials
(gastrins)		Recent Studies (post-2010) (gastrins)
10822612,748659786

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (84.62)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cai, RZ; Groot, K; Pinski, J; Radulovic, S; Schally, AV; Yano, T1
Cai, RZ; Pinski, J; Radulovic, S; Rekasi, Z; Schally, AV; Yano, T1
Banas, M; Cai, RZ; Dembiński, A; Konturek, SJ; Schally, AV; Warzecha, Z1
Cai, RZ; Milovanovic, S; Radulovic, S; Schally, AV; Szepeshazi, K; Szoke, B1
Miller, G; Radulovic, S; Schally, AV1
Groot, K; Halmos, G; Pinski, J; Reile, H; Schally, AV1
Groot, K; Halmos, G; Miller, G; Milovanovic, S; Radulovic, S; Reile, H; Schally, AV; Szepeshazi, K; Yano, T1
Cai, RZ; Groot, K; Halmos, G; O'Byrne, K; Pinski, J; Schally, AV; Szepeshazi, K1
Groot, K; Halmos, G; Pinski, J; Schally, AV; Szepeshazi, K1
Halmos, G; Pinski, J; Schally, AV1
Groot, K; Halmos, G; Schally, AV; Szepeshazi, K1
Bajo, AM; Groot, K; Hebert, F; Krupa, M; Schally, AV; Szepeshazi, K1
Cancella, A; da Rocha, AB; De Nucci, G; DiLeone, LP; Horowitz, M; Pereira, AS; Pohlmann, P; Richter, M; Schunemann, D; Schwartsmann, G; Souza, F; Souza, FH1

Trials

1 trial(s) available for rc 3095 and gastrins

ArticleYear
A phase I trial of the bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC3095 in patients with advanced solid malignancies.
    Investigational new drugs, 2006, Volume: 24, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bombesin; Female; Gastrin-Releasing Peptide; Gastrins; Humans; Injections, Subcutaneous; Male; Middle Aged; Neoplasms; Pain; Peptide Fragments; Skin

2006

Other Studies

12 other study(ies) available for rc 3095 and gastrins

ArticleYear
Endocrine effects of new bombesin/gastrin-releasing peptide antagonists in rats.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 1

    Topics: Amino Acid Sequence; Animals; Blood Glucose; Bombesin; Endocrine Glands; Gastrin-Releasing Peptide; Gastrins; Glucagon; Growth Hormone; Insulin; Male; Molecular Sequence Data; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley

1992
High potency of a new bombesin antagonist (RC-3095) in inhibiting serum gastrin levels; comparison of different routes of administration.
    Regulatory peptides, 1992, Oct-13, Volume: 41, Issue:3

    Topics: Administration, Inhalation; Animals; Bombesin; Gastrin-Releasing Peptide; Gastrins; Injections, Intravenous; Injections, Subcutaneous; Male; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley

1992
The effect of antagonist of receptors for gastrin, cholecystokinin and bombesin on growth of gastroduodenal mucosa and pancreas.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1991, Volume: 42, Issue:3

    Topics: Animals; Benzodiazepinones; Bombesin; Cholecystokinin; Devazepide; DNA; Duodenum; Eating; Fasting; Gastric Mucosa; Gastrins; Intestinal Mucosa; Male; Pancreas; Parietal Cells, Gastric; Peptide Fragments; Phenylurea Compounds; Rats; Rats, Inbred Strains; Receptors, Bombesin; Receptors, Cholecystokinin; Receptors, Neurotransmitter

1991
Inhibitory effect of bombesin/gastrin-releasing peptide antagonist RC-3095 and high dose of somatostatin analogue RC-160 on nitrosamine-induced pancreatic cancers in hamsters.
    Cancer research, 1991, Nov-01, Volume: 51, Issue:21

    Topics: Adenocarcinoma; Amino Acid Sequence; Animals; Antineoplastic Agents; Bombesin; Carcinogens; Cell Membrane; Cricetinae; ErbB Receptors; Female; Gastrins; Mesocricetus; Molecular Sequence Data; Nitrosamines; Organ Size; Pancreatic Neoplasms; Peptide Fragments; Receptors, Bombesin; Receptors, Neurotransmitter; Somatostatin

1991
Inhibition of growth of HT-29 human colon cancer xenografts in nude mice by treatment with bombesin/gastrin releasing peptide antagonist (RC-3095).
    Cancer research, 1991, Nov-01, Volume: 51, Issue:21

    Topics: Animals; Antineoplastic Agents; Bombesin; Cell Division; Cell Line; Colonic Neoplasms; Gastrins; Growth Hormone; Humans; Insulin-Like Growth Factor I; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Somatostatin; Transplantation, Heterologous

1991
Inhibitory effects of somatostatin analogue RC-160 and bombesin/gastrin-releasing peptide antagonist RC-3095 on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer.
    Cancer research, 1994, Jan-01, Volume: 54, Issue:1

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Bombesin; Castration; Cell Division; Drug Screening Assays, Antitumor; ErbB Receptors; Gastrins; Growth Hormone; Male; Molecular Sequence Data; Neoplasm Transplantation; Peptide Fragments; Prostatic Neoplasms; Rats; Somatostatin

1994
Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bombesin; Colonic Neoplasms; Drug Screening Assays, Antitumor; ErbB Receptors; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Humans; Insulin-Like Growth Factor I; Liver Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Peptides; Radioligand Assay; Somatostatin

1994
Effects of somatostatin analogue RC-160 and bombesin/gastrin-releasing peptide antagonists on the growth of human small-cell and non-small-cell lung carcinomas in nude mice.
    British journal of cancer, 1994, Volume: 70, Issue:5

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Body Weight; Bombesin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Gastrin-Releasing Peptide; Gastrins; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Peptide Fragments; Peptides; Receptors, Somatotropin; Somatostatin; Substrate Specificity; Transplantation, Heterologous

1994
Somatostatin analogues and bombesin/gastrin-releasing peptide antagonist RC-3095 inhibit the growth of human glioblastomas in vitro and in vivo.
    Cancer research, 1994, Nov-15, Volume: 54, Issue:22

    Topics: Amino Acid Sequence; Animals; Bombesin; Cell Division; Drug Screening Assays, Antitumor; ErbB Receptors; Gastrins; Glioblastoma; Male; Mice; Mice, Nude; Molecular Sequence Data; Peptide Fragments; Receptors, Bombesin; Somatostatin; Tumor Cells, Cultured

1994
Somatostatin analog RC-160 and bombesin/gastrin-releasing peptide antagonist RC-3095 inhibit the growth of androgen-independent DU-145 human prostate cancer line in nude mice.
    Cancer letters, 1993, Jul-30, Volume: 71, Issue:1-3

    Topics: Amino Acid Sequence; Androgens; Animals; Binding Sites; Body Weight; Bombesin; Cell Line; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Humans; Male; Mice; Mice, Nude; Molecular Sequence Data; Peptide Fragments; Peptides; Prostatic Neoplasms; Somatostatin

1993
Effect of bombesin, gastrin-releasing peptide (GRP)(14-27) and bombesin/GRP receptor antagonist RC-3095 on growth of nitrosamine-induced pancreatic cancers in hamsters.
    International journal of cancer, 1993, May-08, Volume: 54, Issue:2

    Topics: Animals; Body Weight; Bombesin; Carcinoma; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Female; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Insulin-Like Growth Factor I; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Peptide Fragments; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter

1993
Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Mar-19, Volume: 99, Issue:6

    Topics: Adult; Animals; Bombesin; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Division; Epidermal Growth Factor; Estrogens; Female; Gastrins; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptor, ErbB-2; RNA, Messenger; Tumor Cells, Cultured

2002