rc 3095 has been researched along with gastrin-releasing peptide in 44 studies
| Studies (rc 3095) | Trials (rc 3095) | Recent Studies (post-2010) (rc 3095) | Studies (gastrin-releasing peptide) | Trials (gastrin-releasing peptide) | Recent Studies (post-2010) (gastrin-releasing peptide) |
|---|---|---|---|---|---|
| 108 | 2 | 26 | 1,392 | 18 | 252 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (31.82) | 18.2507 |
| 2000's | 11 (25.00) | 29.6817 |
| 2010's | 19 (43.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, RZ; Jaworek, J; Konturek, PK; Konturek, SJ; Schally, AV | 1 |
| Cai, RZ; Groot, K; Pinski, J; Radulovic, S; Schally, AV; Yano, T | 1 |
| Cai, RZ; Pinski, J; Radulovic, S; Rekasi, Z; Schally, AV; Yano, T | 1 |
| Groot, K; Halmos, G; Radulovic, S; Schally, AV; Szepeshazi, K | 1 |
| Cai, RZ; Groot, K; Horvàth, JE; Schally, AV | 1 |
| Cai, RZ; Ertl, T; Groot, K; Horvàth, JE; Qin, Y; Schally, AV | 1 |
| Groot, K; Halmos, G; Miller, G; Milovanovic, S; Radulovic, S; Reile, H; Schally, AV; Szepeshazi, K; Yano, T | 1 |
| Cai, RZ; Groot, K; Halmos, G; O'Byrne, K; Pinski, J; Schally, AV; Szepeshazi, K | 1 |
| Halmos, G; Pinski, J; Schally, AV | 1 |
| Halmos, G; Pinski, J; Schally, AV; Szepeshazi, K | 1 |
| Groot, K; Halmos, G; Schally, AV; Szepeshazi, K | 1 |
| Arencibia, JM; Halmos, G; Koppán, M; Lamharzi, N; Schally, AV | 1 |
| Armatis, P; Groot, K; Kiaris, H; Schally, AV; Sun, B | 1 |
| Arencibia, JM; Cai, RZ; Groot, K; Halmos, G; Kahán, Z; Schally, AV; Sun, B | 1 |
| Gralla, O; Gröne, HJ; Heuser, M; Nustede, R; Pfaar, O; Post, S | 1 |
| Armatis, P; Chatzistamou, I; Schally, AV; Sun, B; Szepeshazi, K | 1 |
| Arencibia, JM; Chatzistamou, I; Groot, K; Hebert, F; Schally, AV; Szepeshazi, K | 1 |
| Henriques, JA; Kopschina, MI; Meller, CA; Roesler, R; Schwartsmann, G; Souza, DO | 1 |
| Gralla, O; Heuser, M; Nustede, R; Post, S | 1 |
| Cancella, A; da Rocha, AB; De Nucci, G; DiLeone, LP; Horowitz, M; Pereira, AS; Pohlmann, P; Richter, M; Schunemann, D; Schwartsmann, G; Souza, F; Souza, FH | 1 |
| Baregamian, N; Chung, DH; Evers, BM; Ishola, TA; Kang, J; Mourot, JM; Rychahou, PG | 1 |
| Amaral, OB; Luft, T; Roesler, R; Schwartsmann, G | 1 |
| Breedlove, SM; Hongu, H; Jordan, CL; Kawata, M; Matsuda, K; Sakamoto, H; Wada, E; Wada, K; Zuloaga, DG | 1 |
| Anisman, H; Merali, Z; Mountney, C | 1 |
| Dal-Pizzol, F; Mina, F; Pereira, DV; Petronilho, F; Ritter, C; Roesler, R; Schwartsmann, G; Steckert, AV | 1 |
| Abujamra, AL; Brunetto, AL; de Farias, CB; Kapczinski, F; Roesler, R; Schmidt, AL; Schwartsmann, G | 1 |
| Damin, DC; Heck, R; Kliemann, LM; Meurer, L; Roesler, R; Rosito, MA; Santos, FS; Schwartsmann, G | 1 |
| Anisman, H; Kent, P; Merali, Z; Mountney, C | 1 |
| Cao, X; Li, P; Mercaldo, V; Wu, LJ; Zhuo, M | 1 |
| Cowan, A; Dun, NJ; Inan, S | 1 |
| Ko, MC; Su, PY | 1 |
| Abujamra, AL; Bonorino, C; Cunha, Fde Q; Czepielewski, RS; Pinto, LG; Porto, BN; Rizzo, LB; Roesler, R; Schwartsmann, G | 1 |
| Charnock-Jones, DS; Cordeaux, Y; Smith, GC; Tattersall, M | 1 |
| Coolen, LM; Kozyrev, N; Lehman, MN | 1 |
| Barbeiro, DF; Block, NL; Constantino, L; da Silva, S; Dal-Pizzol, F; de Souza, CT; Galant, LS; Gelain, DP; Giombelli, VR; Moreira, JC; Pasquali, MA; Petronilho, F; Ritter, C; Roesler, R; Rybarczyk-Filho, JL; Schally, AV; Schwartsmann, G; Soriano, FG; Streck, EL; Tomasi, CD; Vuolo, F; Zanotto-Filho, A | 1 |
| Dal-Pizzol, F; Danielski, LG; Petronilho, F; Roesler, R; Schwartsmann, G | 1 |
| Ko, MC; Sukhtankar, DD | 1 |
| Akiyama, T; Carstens, E; Carstens, MI; Takamori, K; Tominaga, M | 1 |
| Castellone, MD; Laukkanen, MO | 1 |
| Bogo, MR; Campos, MM; Canevese, FF; Cheng, YC; Danesi, GM; Laedermann, C; Lerner, EA; Machado, GD; Pereira, PJ; Pereira, TC; Reddy, VB; Talbot, S | 1 |
| Ding, H; Kiguchi, N; Kishioka, S; Ko, MC; Peters, CM; Sukhtankar, DD; Tanaka, K | 1 |
| Antle, MC; Basu, P; Chan, RK; Chow, SL; Duong, B; Enkhbold, Y; Jeffers, RT; Smith, VM; Sterniczuk, R | 1 |
| Arae, K; Ikeda, T; Kawada, M; Kimura, T; Matsumoto, K; Matsumoto, Y; Nakae, S; Saito, K; Sakurai, H; Yokoi, H | 1 |
| Bae, MK; Bae, SK; Kim, HJ; Kim, MK; Kim, Y; Park, HJ | 1 |
2 review(s) available for rc 3095 and gastrin-releasing peptide
| Article | Year |
|---|---|
Gastrin-releasing peptide as a molecular target for inflammatory diseases: an update.
Topics: Air Pollution; Animals; Anti-Inflammatory Agents; Bombesin; Disease Models, Animal; Gastrin-Releasing Peptide; Gene Expression Regulation, Neoplastic; Humans; Mice; Molecular Targeted Therapy; Neuroimmunomodulation; Peptide Fragments; Receptors, Bombesin; Respiratory Hypersensitivity; Signal Transduction | 2013 |
Gastrin-Releasing Peptide Receptor Targeting in Cancer Treatment: Emerging Signaling Networks and Therapeutic Applications.
Topics: Animals; Antineoplastic Agents; Bombesin; Clinical Trials as Topic; Female; Gastrin-Releasing Peptide; Humans; Indoles; Male; Neoplasms; Peptide Fragments; Receptors, Bombesin; Signal Transduction | 2016 |
2 trial(s) available for rc 3095 and gastrin-releasing peptide
| Article | Year |
|---|---|
A phase I trial of the bombesin/gastrin-releasing peptide (BN/GRP) antagonist RC3095 in patients with advanced solid malignancies.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bombesin; Female; Gastrin-Releasing Peptide; Gastrins; Humans; Injections, Subcutaneous; Male; Middle Aged; Neoplasms; Pain; Peptide Fragments; Skin | 2006 |
Gastrin-releasing peptide receptor antagonism induces protection from lethal sepsis: involvement of toll-like receptor 4 signaling.
Topics: Adult; Animals; Bombesin; Cell Movement; Cell Nucleus; Chemokines; Disease Models, Animal; Female; Gastrin-Releasing Peptide; Gene Expression Regulation; Humans; Interleukin-6; Lipopolysaccharides; Lung; Macrophages; Male; Mice; Middle Aged; Models, Biological; Peptide Fragments; Rats; Receptors, Bombesin; RNA, Messenger; Sepsis; Signal Transduction; Toll-Like Receptor 4; Transcription Factor RelA | 2012 |
40 other study(ies) available for rc 3095 and gastrin-releasing peptide
| Article | Year |
|---|---|
Actions of novel bombesin receptor antagonists on pancreatic secretion in rats.
Topics: Amino Acid Sequence; Amylases; Animals; Bombesin; Gastrin-Releasing Peptide; In Vitro Techniques; Molecular Sequence Data; Pancreas; Peptide Fragments; Peptides; Rats; Receptors, Bombesin; Receptors, Neurotransmitter | 1992 |
Endocrine effects of new bombesin/gastrin-releasing peptide antagonists in rats.
Topics: Amino Acid Sequence; Animals; Blood Glucose; Bombesin; Endocrine Glands; Gastrin-Releasing Peptide; Gastrins; Glucagon; Growth Hormone; Insulin; Male; Molecular Sequence Data; Peptide Fragments; Peptides; Rats; Rats, Sprague-Dawley | 1992 |
High potency of a new bombesin antagonist (RC-3095) in inhibiting serum gastrin levels; comparison of different routes of administration.
Topics: Administration, Inhalation; Animals; Bombesin; Gastrin-Releasing Peptide; Gastrins; Injections, Intravenous; Injections, Subcutaneous; Male; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1992 |
Growth inhibition of estrogen-dependent and estrogen-independent MXT mammary cancers in mice by the bombesin and gastrin-releasing peptide antagonist RC-3095.
Topics: Animals; Antineoplastic Agents; Bombesin; ErbB Receptors; Estrogens; Female; Gastrin-Releasing Peptide; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Hormone-Dependent; Peptide Fragments; Peptides | 1992 |
Development of a radioimmunoassay for a pseudononapeptide bombesin/GRP antagonist with antitumor activity.
Topics: Animals; Antineoplastic Agents; Bombesin; Gastrin-Releasing Peptide; Male; Oligopeptides; Peptide Fragments; Peptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity | 1995 |
Antagonists of bombesin/gastrin-releasing peptide inhibit growth of SW-1990 human pancreatic adenocarcinoma and production of cyclic AMP.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bombesin; Cell Division; Cyclic AMP; Gastrin-Releasing Peptide; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms; Peptide Fragments; Peptides; Tumor Cells, Cultured | 1995 |
Inhibitory effects of antagonists of bombesin/gastrin releasing peptide (GRP) and somatostatin analog (RC-160) on growth of HT-29 human colon cancers in nude mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bombesin; Colonic Neoplasms; Drug Screening Assays, Antitumor; ErbB Receptors; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Humans; Insulin-Like Growth Factor I; Liver Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Peptides; Radioligand Assay; Somatostatin | 1994 |
Effects of somatostatin analogue RC-160 and bombesin/gastrin-releasing peptide antagonists on the growth of human small-cell and non-small-cell lung carcinomas in nude mice.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Binding Sites; Body Weight; Bombesin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Gastrin-Releasing Peptide; Gastrins; Gonadotropin-Releasing Hormone; Growth Hormone; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Peptide Fragments; Peptides; Receptors, Somatotropin; Somatostatin; Substrate Specificity; Transplantation, Heterologous | 1994 |
Somatostatin analog RC-160 and bombesin/gastrin-releasing peptide antagonist RC-3095 inhibit the growth of androgen-independent DU-145 human prostate cancer line in nude mice.
Topics: Amino Acid Sequence; Androgens; Animals; Binding Sites; Body Weight; Bombesin; Cell Line; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Humans; Male; Mice; Mice, Nude; Molecular Sequence Data; Peptide Fragments; Peptides; Prostatic Neoplasms; Somatostatin | 1993 |
Antagonists of bombesin/gastrin-releasing peptides as adjuncts to agonists of luteinizing hormone-releasing hormone in the treatment of experimental prostate cancer.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bombesin; Connective Tissue; ErbB Receptors; Gastrin-Releasing Peptide; Gonadotropin-Releasing Hormone; Male; Mitosis; Peptide Fragments; Peptides; Prostatic Neoplasms; Rats; Rats, Inbred F344; Rats, Inbred Strains; Receptor, IGF Type 1; Receptors, Bombesin; Testosterone; Time Factors | 1993 |
Effect of bombesin, gastrin-releasing peptide (GRP)(14-27) and bombesin/GRP receptor antagonist RC-3095 on growth of nitrosamine-induced pancreatic cancers in hamsters.
Topics: Animals; Body Weight; Bombesin; Carcinoma; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Female; Gastrin-Releasing Peptide; Gastrins; Growth Hormone; Insulin-Like Growth Factor I; Mesocricetus; Nitrosamines; Pancreatic Neoplasms; Peptide Fragments; Peptides; Receptors, Bombesin; Receptors, Neurotransmitter | 1993 |
Bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II inhibit tumor growth and decrease the levels and mRNA expression of epidermal growth factor receptors in H-69 small cell lung carcinoma.
Topics: Animals; Anticarcinogenic Agents; Antigens, Neoplasm; Antineoplastic Agents; Blotting, Southern; Bombesin; Carcinoma, Small Cell; ErbB Receptors; Gastrin-Releasing Peptide; Lung Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Nude; Neoplasm Transplantation; Peptide Fragments; Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous; Tumor Cells, Cultured | 1998 |
Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide.
Topics: Animals; Base Sequence; Bombesin; Brain Neoplasms; Cell Division; DNA Primers; Gastrin-Releasing Peptide; Glioblastoma; Humans; Mice; Mice, Nude; Peptide Fragments; Proto-Oncogene Proteins c-fos; RNA, Messenger | 1999 |
Inhibition of growth of MDA-MB-468 estrogen-independent human breast carcinoma by bombesin/gastrin-releasing peptide antagonists RC-3095 and RC-3940-II.
Topics: Animals; Antineoplastic Agents; Bombesin; Breast Neoplasms; Carcinoma; Dose-Response Relationship, Drug; ErbB Receptors; Female; Gastrin-Releasing Peptide; Gene Expression Regulation, Neoplastic; Humans; Injections, Subcutaneous; Mice; Mice, Nude; Neoplasm Transplantation; Neurokinin B; Peptide Fragments; Polymerase Chain Reaction; Receptors, Bombesin; Remission Induction; RNA, Messenger; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Impact of gastrin-releasing peptide on intestinal microcirculation after ischemia-reperfusion in rats.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Bombesin; Female; Gastrin-Releasing Peptide; Injections, Intravenous; Intestines; Ischemia; Microcirculation; Microscopy, Fluorescence; Peptide Fragments; Rats; Rats, Wistar; Reperfusion Injury | 2000 |
Inhibition of growth of OV-1063 human epithelial ovarian cancers and c- jun and c- fos oncogene expression by bombesin antagonists.
Topics: Animals; Antineoplastic Agents; Bombesin; Cell Division; Epithelium; Female; Gastrin-Releasing Peptide; Gene Expression; Genes, fos; Genes, jun; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Peptide Fragments; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Bombesin; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Inhibition of growth of ES-2 human ovarian cancers by bombesin antagonist RC-3095, and luteinizing hormone-releasing hormone antagonist Cetrorelix.
Topics: Adenocarcinoma, Clear Cell; Animals; Antineoplastic Agents, Hormonal; Bombesin; ErbB Receptors; Female; Gastrin-Releasing Peptide; Gene Expression Regulation, Neoplastic; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Mice; Mice, Nude; Neoplasm Proteins; Ovarian Neoplasms; Peptide Fragments; Receptors, Bombesin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Specific Pathogen-Free Organisms; Xenograft Model Antitumor Assays | 2001 |
Intrahippocampal infusion of the bombesin/gastrin-releasing peptide antagonist RC-3095 impairs inhibitory avoidance retention.
Topics: Animals; Avoidance Learning; Bombesin; Catheterization; Dose-Response Relationship, Drug; Gastrin-Releasing Peptide; Hippocampus; Histocytochemistry; Infusion Pumps; Male; Memory; Memory, Short-Term; Peptide Fragments; Rats; Rats, Wistar; Reaction Time; Receptors, Bombesin; Retention, Psychology; Time Factors | 2003 |
[Significance of regulatory peptide GRP for microcirculation of the small intestine after ischemia/reperfusion].
Topics: Animals; Blood Flow Velocity; Bombesin; Gastrin-Releasing Peptide; Intestine, Small; Ischemia; Microcirculation; Peptide Fragments; Rats; Rats, Wistar; Reperfusion Injury | 1998 |
Bombesin induces angiogenesis and neuroblastoma growth.
Topics: Animals; Anticarcinogenic Agents; Bombesin; Cell Line, Tumor; Cell Proliferation; Gastrin-Releasing Peptide; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Neuroblastoma; Peptide Fragments; Receptors, Bombesin; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2007 |
Transient disruption of fear-related memory by post-retrieval inactivation of gastrin-releasing peptide or N-methyl-D-aspartate receptors in the hippocampus.
Topics: Analysis of Variance; Animals; Avoidance Learning; Bombesin; Excitatory Amino Acid Antagonists; Fear; Gastrin-Releasing Peptide; Hippocampus; Male; Mental Recall; Peptide Fragments; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine | 2008 |
Sexually dimorphic gastrin releasing peptide system in the spinal cord controls male reproductive functions.
Topics: Androgen-Insensitivity Syndrome; Animals; Behavior, Animal; Bombesin; Castration; Cholera Toxin; Dose-Response Relationship, Drug; Ejaculation; Female; Gastrin-Releasing Peptide; Horseradish Peroxidase; Male; Nitric Oxide Synthase Type I; Penile Erection; Peptide Fragments; Protein Binding; Rats; Rats, Long-Evans; Rats, Mutant Strains; Rats, Sprague-Dawley; Reaction Time; Receptors, Androgen; Sex Characteristics; Spinal Cord; Testosterone | 2008 |
Effects of gastrin-releasing peptide agonist and antagonist administered to the basolateral nucleus of the amygdala on conditioned fear in the rat.
Topics: Amygdala; Animals; Bombesin; Conditioning, Psychological; Dose-Response Relationship, Drug; Fear; Gastrin-Releasing Peptide; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2008 |
Effects of an antagonist of the gastrin-releasing peptide receptor in an animal model of uveitis.
Topics: Animals; Anticarcinogenic Agents; Aqueous Humor; Bombesin; Chemokine CCL2; Dexamethasone; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Gastrin-Releasing Peptide; Glucocorticoids; Iris; Lipopolysaccharides; Male; Peptide Fragments; Peroxidase; Protein Carbonylation; Rats; Rats, Wistar; Receptors, Bombesin; Thiobarbituric Acid Reactive Substances; Tumor Necrosis Factor-alpha; Uveitis | 2009 |
BDNF and PDE4, but not the GRPR, regulate viability of human medulloblastoma cells.
Topics: Animals; Antineoplastic Agents; Bombesin; Brain-Derived Neurotrophic Factor; Cell Survival; Child; Cyclic Nucleotide Phosphodiesterases, Type 4; Gastrin-Releasing Peptide; Gastrointestinal Agents; Humans; Medulloblastoma; Neurotransmitter Agents; Peptide Fragments; Phosphodiesterase Inhibitors; Receptor, trkB; Receptors, Bombesin; Recombinant Proteins; Rolipram | 2010 |
Effects of the gastrin-releasing peptide antagonist RC-3095 in a rat model of ulcerative colitis.
Topics: Animals; Bombesin; Colitis, Ulcerative; Colon; Female; Gastrin-Releasing Peptide; Immunohistochemistry; Male; Peptide Fragments; Rats; Rats, Wistar | 2010 |
Effects of intracerebral ventricular administration of gastrin-releasing peptide and its receptor antagonist RC-3095 on learned fear responses in the rat.
Topics: Analysis of Variance; Animals; Association Learning; Bombesin; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Gastrin-Releasing Peptide; Hormone Antagonists; Injections, Intraventricular; Male; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Reflex, Startle | 2011 |
Facilitation of the inhibitory transmission by gastrin-releasing peptide in the anterior cingulate cortex.
Topics: Action Potentials; Amygdala; Animals; Bombesin; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Gastrin-Releasing Peptide; Glutamates; Gyrus Cinguli; Inhibitory Postsynaptic Potentials; Interneurons; Mice; Mice, Inbred C57BL; Neural Inhibition; Peptide Fragments; Picrotoxin; Pyramidal Cells; Receptors, Bombesin; Synaptic Transmission | 2010 |
Investigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bombesin; Compulsive Behavior; Ganglia, Spinal; Gastrin-Releasing Peptide; Grooming; Guanidines; Locomotion; Male; Mice; Morphinans; Naltrexone; Nerve Fibers; Peptide Fragments; Pirenzepine; Pruritus; Receptor, Muscarinic M1; Receptors, Bombesin; Receptors, Opioid, kappa; Skin; Spinal Cord; Spiro Compounds | 2011 |
The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats.
Topics: Animals; Bombesin; Dose-Response Relationship, Drug; Gastrin-Releasing Peptide; Indoles; Infusions, Intraventricular; Male; Neurokinin B; Neurotransmitter Agents; Peptide Fragments; Pruritus; Pyridines; Rats; Rats, Wistar; Receptors, Bombesin | 2011 |
Gastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophils.
Topics: Analysis of Variance; Animals; Bombesin; Chemotaxis; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gastrin-Releasing Peptide; Humans; Inflammation; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Neutrophils; Peptide Fragments; Receptors, Bombesin | 2012 |
Expression of gastrin-releasing peptide is increased by prolonged stretch of human myometrium, and antagonists of its receptor inhibit contractility.
Topics: Biopsy; Blotting, Western; Bombesin; Female; Gastrin-Releasing Peptide; Gene Expression Profiling; Hormone Antagonists; Humans; Immunohistochemistry; Indoles; Mechanotransduction, Cellular; Myometrium; Oligonucleotide Array Sequence Analysis; Oxytocics; Oxytocin; Peptide Fragments; Potassium Chloride; Pregnancy; Premature Birth; Receptors, Bombesin; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tissue Culture Techniques; Up-Regulation; Uterine Contraction | 2012 |
Activation of gastrin-releasing peptide receptors in the lumbosacral spinal cord is required for ejaculation in male rats.
Topics: Animals; Bombesin; Dose-Response Relationship, Drug; Ejaculation; Electric Stimulation; Galanin; Gastrin-Releasing Peptide; Infusions, Spinal; Lumbosacral Region; Male; Penis; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Bombesin; Seminal Vesicles; Spinal Cord | 2012 |
Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice.
Topics: Animals; Behavior, Animal; Bombesin; Gastrin-Releasing Peptide; Indoles; Injections, Spinal; Male; Mice; Morphine; Motor Activity; Peptide Fragments; Pruritus; Pyridines; Receptors, Bombesin; Spinal Cord | 2013 |
Roles of glutamate, substance P, and gastrin-releasing peptide as spinal neurotransmitters of histaminergic and nonhistaminergic itch.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Antirheumatic Agents; Bombesin; Chloroquine; Drug Combinations; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gastrin-Releasing Peptide; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Neurokinin-1 Receptor Antagonists; Neurons; Peptide Fragments; Piperidines; Pruritus; Substance P; Vesicular Glutamate Transport Protein 2 | 2014 |
GRPR/PI3Kγ: Partners in Central Transmission of Itch.
Topics: Action Potentials; Animals; Anticarcinogenic Agents; Bombesin; Capsaicin; Central Nervous System; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Gastrin-Releasing Peptide; Indoles; Male; Mice; Neurons; p-Methoxy-N-methylphenethylamine; Pain Threshold; Peptide Fragments; Phosphatidylinositol 3-Kinase; Pruritus; Quinoxalines; Reaction Time; Receptors, Bombesin; Synaptic Transmission; Thiazolidinediones | 2015 |
Spinal Functions of B-Type Natriuretic Peptide, Gastrin-Releasing Peptide, and Their Cognate Receptors for Regulating Itch in Mice.
Topics: Animals; Atrial Natriuretic Factor; Bombesin; Gastrin-Releasing Peptide; Male; Mice; Natriuretic Peptide, Brain; Peptide Fragments; Pruritus; Receptors, Atrial Natriuretic Factor; Receptors, Bombesin; Spinal Cord; Tetrahydroisoquinolines | 2016 |
Phase shifts to light are altered by antagonists to neuropeptide receptors.
Topics: Animals; Bombesin; Circadian Rhythm; Cricetinae; Gastrin-Releasing Peptide; Light; Male; Peptide Fragments; Photic Stimulation; Receptors, Neuropeptide; Suprachiasmatic Nucleus; Vasoactive Intestinal Peptide | 2016 |
Gastrin-Releasing Peptide Is Involved in the Establishment of Allergic Rhinitis in Mice.
Topics: Animals; Bombesin; Disease Models, Animal; Female; Gastrin-Releasing Peptide; Inflammation; Mice; Mice, Inbred BALB C; Nasal Mucosa; Peptide Fragments; Receptors, Bombesin; Rhinitis, Allergic | 2018 |
Involvement of Gastrin-Releasing Peptide Receptor in the Regulation of Adipocyte Differentiation in 3T3-L1 Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Bombesin; Cell Differentiation; Cyclic AMP Response Element-Binding Protein; Diet, High-Fat; Down-Regulation; Gastrin-Releasing Peptide; Gene Knockdown Techniques; Mice; Obesity; Peptide Fragments; Rats; Receptors, Bombesin | 2018 |