Page last updated: 2024-09-03

rb 104 and gamma-aminobutyric acid

rb 104 has been researched along with gamma-aminobutyric acid in 7 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Compound Research Comparison

Studies
(rb 104)
Trials
(rb 104)
Recent Studies (post-2010)
(rb 104)
Studies
(gamma-aminobutyric acid)
Trials
(gamma-aminobutyric acid)
Recent Studies (post-2010) (gamma-aminobutyric acid)
70040,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomyrb 104 (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beaumont, A; Crine, P; Fournié-Zaluski, MC; Laï-Kuen, R; Roques, BP; Soleilhac, JM; Turcaud, S1
Aloyz, RS; Bawab, W; Crine, P; DesGroseillers, L; Roques, BP1
Bawab, W; Crine, P; Fournié-Zaluski, MC; Landry, C; Roques, BP; Santagata, P; Vinay, P1
Ardaillou, R; Dussaule, JC; Ledoux, S; Soleilhac, JM; Stefanski, A; Tharaux, PL1
Burrell, LM; Casely, D; Farina, N; Johnston, CI; Risvanis, J; Woollard, D1
Bawab, W; Castellucci, VF; DesGroseillers, L; Storozhuk, MV; Wickham, L; Yang, XF; Zappulla, JP1
Burrell, LM; Casley, DJ; Hubner, RA; Johnston, CI; Kubota, E1

Other Studies

7 other study(ies) available for rb 104 and gamma-aminobutyric acid

ArticleYear
Development of [125I]RB104, a potent inhibitor of neutral endopeptidase 24.11, and its use in detecting nanogram quantities of the enzyme by "inhibitor gel electrophoresis".
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: Animals; Antigens, Differentiation; Antigens, Neoplasm; Cell Membrane; Electrophoresis, Polyacrylamide Gel; gamma-Aminobutyric Acid; Iodobenzenes; Kidney; Kinetics; Neprilysin; Protease Inhibitors; Rabbits

1992
Identification and characterization of a neutral endopeptidase activity in Aplysia californica.
    The Biochemical journal, 1993, Dec-01, Volume: 296 ( Pt 2)

    Topics: Animals; Aplysia; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Enkephalin, Leucine; gamma-Aminobutyric Acid; Iodobenzenes; Kidney; Neprilysin; Peptide Fragments; Protease Inhibitors; Protein Binding; Rats; Substrate Specificity

1993
Characterization of neutral endopeptidase 24.11 in dog glomeruli.
    The Biochemical journal, 1993, May-01, Volume: 291 ( Pt 3)

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Blotting, Western; Dogs; Enkephalin, Leucine-2-Alanine; gamma-Aminobutyric Acid; Glycopeptides; Glycosylation; Immunoblotting; Iodobenzenes; Kidney Glomerulus; Kidney Tubules, Proximal; Microvilli; Neprilysin; Octoxynol; Polyethylene Glycols; Thiorphan

1993
EGF and TGF-beta regulate neutral endopeptidase expression in renal vascular smooth muscle cells.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Animals; Cell Division; Cell Membrane; Cells, Cultured; Epidermal Growth Factor; Flow Cytometry; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Iodobenzenes; Kidney Cortex; Kinetics; Male; Muscle, Smooth, Vascular; Neprilysin; Protease Inhibitors; Rabbits; Time Factors; Transcription, Genetic; Transforming Growth Factor beta

1997
Inhibition of neutral endopeptidase, the degradative enzyme for natriuretic peptides, in rat kidney after oral SCH 42495.
    Clinical science (London, England : 1979), 1997, Volume: 93, Issue:1

    Topics: Administration, Oral; Animals; Atrial Natriuretic Factor; Binding, Competitive; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Iodine Radioisotopes; Iodobenzenes; Kidney; Methionine; Neprilysin; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Sprague-Dawley; Renin; Time Factors

1997
Cloning and characterization of Aplysia neutral endopeptidase, a metallo-endopeptidase involved in the extracellular metabolism of neuropeptides in Aplysia californica.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-01, Volume: 19, Issue:11

    Topics: Amino Acid Sequence; Animals; Aplysia; Base Sequence; Blotting, Western; Cloning, Molecular; DNA, Complementary; gamma-Aminobutyric Acid; Ganglia, Invertebrate; In Situ Hybridization; Iodine Radioisotopes; Iodobenzenes; Molecular Sequence Data; Neprilysin; Neuropeptides; Protease Inhibitors; Radioligand Assay; Sequence Homology, Nucleic Acid

1999
In-vitro and in-vivo inhibition of rat neutral endopeptidase and angiotensin converting enzyme with the vasopeptidase inhibitor gemopatrilat.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; gamma-Aminobutyric Acid; In Vitro Techniques; Iodine Radioisotopes; Iodobenzenes; Male; Neprilysin; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Time Factors

2001