Page last updated: 2024-09-03

rb 101 and naltrindole

rb 101 has been researched along with naltrindole in 10 studies

Compound Research Comparison

Studies
(rb 101)
Trials
(rb 101)
Recent Studies (post-2010)
(rb 101)
Studies
(naltrindole)
Trials
(naltrindole)
Recent Studies (post-2010) (naltrindole)
57028010139

Protein Interaction Comparison

ProteinTaxonomyrb 101 (IC50)naltrindole (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.0007
Delta-type opioid receptorHomo sapiens (human)0.0006

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fournié-Zaluski, MC; Noble, F; Roques, BP; Turcaud, S1
Blommaert, A; Fournié-Zaluski, MC; Noble, F; Roques, BP1
Corringer, PJ; Dauge, V; Roques, BP1
Noble, F; Roques, BP; Smadja, C1
Krylatov, AV; Lishmanov, IuB; Maslov, LN; Uskina, EV1
Gilbert-Rahola, J; Maldonado, R; Micó, JA; Roques, BP; Smadja, C; Tejedor-Real, P1
Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Fournié-Zaluski, MC; Méen, M; Roques, BP1
Guen, SL; Kieffer, BL; Nieto, MM; Noble, F; Roques, BP1
Folk, JE; Jutkiewicz, EM; Mosberg, HI; Rice, KC; Sobczyk-Kojiro, K; Torregrossa, MM; Watson, SJ; Woods, JH1
Benturquia, N; Bilkei-Gorzo, A; Noble, F; Roques, BP; Zimmer, A1

Other Studies

10 other study(ies) available for rb 101 and naltrindole

ArticleYear
Repeated systemic administration of the mixed inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphine.
    European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1

    Topics: Analgesics; Animals; Disulfides; Dose-Response Relationship, Drug; Drug Tolerance; Indoles; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Phenylalanine; Prodrugs; Reaction Time

1992
A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: Analgesics; Animals; Disulfides; Enkephalins; Formaldehyde; Indoles; Male; Meglumine; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Phenylalanine; Receptors, Cholecystokinin; Receptors, Opioid, delta; Receptors, Opioid, mu

1995
CCKA, but not CCKB, agonists suppress the hyperlocomotion induced by endogenous enkephalins, protected from enzymatic degradation by systemic RB 101.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2

    Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalins; Enzyme Inhibitors; Male; Mice; Molecular Sequence Data; Motor Activity; Naltrexone; Narcotic Antagonists; Peptide Fragments; Phenylalanine; Receptors, Cholecystokinin

1995
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Amino Acid Sequence; Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide

1994
[Opiatergic mechanisms of antiarrhythmic effect of adaptation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:9

    Topics: Adaptation, Physiological; Animals; Arrhythmias, Cardiac; Calcium Chloride; Disulfides; Endorphins; Enzyme Inhibitors; Epinephrine; Male; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Rats; Rats, Wistar; Receptors, Opioid

1996
Involvement of delta-opioid receptors in the effects induced by endogenous enkephalins on learned helplessness model.
    European journal of pharmacology, 1998, Jul-31, Volume: 354, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Disulfides; Drug Interactions; Enkephalins; Helplessness, Learned; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Phenylalanine; Rats; Rats, Wistar; Receptors, Opioid, delta

1998
Enhancement of the effects of a complete inhibitor of enkephalin-catabolizing enzymes, RB 101, by a cholecystokinin-B receptor antagonist in diabetic rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:1

    Topics: Aminopeptidases; Animals; Diabetes Mellitus, Experimental; Disulfides; Drug Synergism; Indoles; Male; Meglumine; Naloxone; Naltrexone; Neprilysin; Pain; Pain Measurement; Phenylalanine; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors; Vocalization, Animal; Weight Loss

2001
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; Emotions; Enkephalins; Enzyme Inhibitors; Exploratory Behavior; Freezing Reaction, Cataleptic; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Phenylalanine; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Swimming; Time Factors

2005
Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Disulfides; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Frontal Lobe; Hippocampus; Injections, Intravenous; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming

2006
Use of preproenkephalin knockout mice and selective inhibitors of enkephalinases to investigate the role of enkephalins in various behaviours.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; CD13 Antigens; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Injections, Intravenous; Mice; Mice, Inbred DBA; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Protein Precursors; Swimming

2008