rb 101 has been researched along with devazepide in 5 studies
| Studies (rb 101) | Trials (rb 101) | Recent Studies (post-2010) (rb 101) | Studies (devazepide) | Trials (devazepide) | Recent Studies (post-2010) (devazepide) |
|---|---|---|---|---|---|
| 57 | 0 | 2 | 780 | 5 | 42 |
| Protein | Taxonomy | rb 101 (IC50) | devazepide (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.0009 | |
| Gastrin/cholecystokinin type B receptor | Rattus norvegicus (Norway rat) | 0.0008 | |
| Cholecystokinin receptor type A | Homo sapiens (human) | 0.0002 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.245 | |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | 0.27 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corringer, PJ; Dauge, V; Roques, BP | 1 |
| Noble, F; Roques, BP; Smadja, C | 1 |
| Derrien, M; Maldonado, R; Noble, F; Roques, BP | 1 |
| Fournié-Zaluski, MC; Fuentes, JA; Hernando, F; Roques, BP; Ruiz-Gayo, M | 1 |
| Besson, JM; Buritova, J; Fournié-Zaluski, MC; Honore, P; Roques, BP | 1 |
5 other study(ies) available for rb 101 and devazepide
| Article | Year |
|---|---|
CCKA, but not CCKB, agonists suppress the hyperlocomotion induced by endogenous enkephalins, protected from enzymatic degradation by systemic RB 101.
Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalins; Enzyme Inhibitors; Male; Mice; Molecular Sequence Data; Motor Activity; Naltrexone; Narcotic Antagonists; Peptide Fragments; Phenylalanine; Receptors, Cholecystokinin | 1995 |
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
Topics: Amino Acid Sequence; Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide | 1994 |
Association of the peptidase inhibitor RB 101 and a CCK-B antagonist strongly enhances antinociceptive responses.
Topics: Analgesics; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Drug Synergism; Male; Mice; Pain Measurement; Phenylalanine; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Cholecystokinin | 1993 |
Antidepressant-like effects of CCK(B) receptor antagonists: involvement of the opioid system.
Topics: Animals; Antidepressive Agents; Benzodiazepinones; Devazepide; Disulfides; Endorphins; Male; Mice; Naloxone; Naltrexone; Phenylalanine; Phenylurea Compounds; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide | 1996 |
Antinociceptive effects of RB101, a complete inhibitor of enkephalin-catabolizing enzymes, are enhanced by a cholecystokinin type B receptor antagonist, as revealed by noxiously evoked spinal c-Fos expression in rats.
Topics: Analgesics; Animals; Benzodiazepinones; Devazepide; Disulfides; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Indoles; Male; Meglumine; Pain; Phenylalanine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spinal Cord | 1997 |