Page last updated: 2024-08-23

razoxane and sobuzoxane

razoxane has been researched along with sobuzoxane in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (50.00)18.2507
2000's2 (20.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andoh, T; Ikegami, Y; Ishida, R; Tanabe, K1
Hoshino, A; Inaba, M; Komatsu, T; Narita, T; Takase, M; Tsukagoshi, S; Yaguchi, S1
Azuma, Y; Kizaki, H; Onishi, Y1
Furue, H1
Maehara, Y; Sugimachi, K; Yoshida, M1
Ding, J; Hu, CX; Huang, M; Li, MH; Lin, LP; Lu, DY; Lu, W; Tong, LJ; Xu, CH; Yang, WY; Zhang, XW1
Ding, J; Huang, M; Lu, DY; Xu, B; Xu, CH; Zhu, H1
Lu, DY; Lu, TR2
Jirkovská, A; Karabanovich, G; Piskáčková, HB; Reimerová, P; Roh, J; Šimůnek, T; Štěrbová-Kovaříková, P1

Reviews

3 review(s) available for razoxane and sobuzoxane

ArticleYear
[Topoisomerase inhibitors developing in Japan].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzopyrans; Camptothecin; Diketopiperazines; Glycosides; Humans; Irinotecan; Neoplasms; Phenazines; Piperazines; Razoxane; Topotecan

1993
Anticancer activities and mechanisms of bisdioxopiperazine compounds probimane and MST-16.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Humans; Mice; Mice, Inbred C57BL; Piperazines; Razoxane

2010
Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Transformed; Fibrinogen; Humans; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Piperazines; Razoxane

2010

Other Studies

7 other study(ies) available for razoxane and sobuzoxane

ArticleYear
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives.
    Cancer research, 1991, Sep-15, Volume: 51, Issue:18

    Topics: Antineoplastic Agents; Diketopiperazines; DNA; Piperazines; Razoxane; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1991
Antitumor activity of MST-16, a novel derivative of bis(2,6-dioxopiperazine), in murine tumor models.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Leukemia P388; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Piperazines; Razoxane; Structure-Activity Relationship; Tumor Cells, Cultured

1990
bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cells, Cultured; Cycloheximide; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Gene Expression Regulation; Male; Mice; Mice, Inbred BALB C; Nucleic Acid Conformation; Piperazines; Razoxane; Thymus Gland; Topoisomerase I Inhibitors

1994
MST-16, a novel bis-dioxopiperazine anticancer agent, ameliorates doxorubicin-induced acute toxicity while maintaining antitumor efficacy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Digestive System; Doxorubicin; Female; Humans; Lethal Dose 50; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Piperazines; Prodrugs; Razoxane; Survival Analysis; Tumor Cells, Cultured

1999
Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines.
    BMC pharmacology, 2005, Jun-20, Volume: 5

    Topics: Antineoplastic Agents; Chromosome Segregation; G2 Phase; Humans; Piperazines; Razoxane; Tumor Cells, Cultured

2005
Medicinal chemistry of probimane and MST-16: comparison of anticancer effects between bisdioxopiperazines.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2006, Volume: 2, Issue:4

    Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Mice; Mice, Nude; Molecular Structure; Piperazines; Razoxane; Structure-Activity Relationship; Time Factors; Xenograft Model Antitumor Assays

2006
UHPLC-MS/MS method for analysis of sobuzoxane, its active form ICRF-154 and metabolite EDTA-diamide and its application to bioactivation study.
    Scientific reports, 2019, 03-14, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chromatography, High Pressure Liquid; Edetic Acid; Myocytes, Cardiac; Piperazines; Rats; Rats, Wistar; Razoxane; Tandem Mass Spectrometry

2019