razoxane has been researched along with hydroxyl radical in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Myers, CE; Politi, PM; Rajagopalan, S; Sinha, BK | 1 |
| Hasinoff, BB | 1 |
| Hasinoff, BB; Malisza, KL | 1 |
| Buss, JL; Hasinoff, BB | 1 |
| Thomas, C; Vile, GF; Winterbourn, CC | 1 |
5 other study(ies) available for razoxane and hydroxyl radical
| Article | Year |
|---|---|
Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity.
Topics: Animals; Doxorubicin; Free Radicals; Heart; Hydroxides; Hydroxyl Radical; Male; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Razoxane; Superoxide Dismutase | 1988 |
NADPH-cytochrome-P450 reductase promotes hydroxyl radical production by the iron complex of ADR-925, the hydrolysis product of ICRF-187 (dexrazoxane).
Topics: Animals; Catalase; Chelating Agents; Edetic Acid; Electron Spin Resonance Spectroscopy; Ethylenediamines; Glycine; Hydroxyl Radical; Iron Chelating Agents; Models, Chemical; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Razoxane; Spectrophotometry, Ultraviolet | 1995 |
Doxorubicin reduces the iron(III) complexes of the hydrolysis products of the antioxidant cardioprotective agent dexrazoxane (ICRF-187) and produces hydroxyl radicals.
Topics: Aerobiosis; Antibiotics, Antineoplastic; Antioxidants; Chelating Agents; Doxorubicin; Electron Spin Resonance Spectroscopy; Ethylenediamines; Ferric Compounds; Ferrous Compounds; Glycine; Heart; Hydrolysis; Hydroxyl Radical; Mitoxantrone; Models, Chemical; Oxidation-Reduction; Razoxane | 1995 |
Ferrous ion strongly promotes the ring opening of the hydrolysis intermediates of the antioxidant cardioprotective agent dexrazoxane (ICRF-187).
Topics: Chromatography, High Pressure Liquid; Ferric Compounds; Ferrous Compounds; Hydrogen-Ion Concentration; Hydrolysis; Hydroxyl Radical; Models, Molecular; Razoxane; Spectrophotometry | 1995 |
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction.
Topics: Ascorbic Acid; Chelating Agents; Deoxyribose; Dimethyl Sulfoxide; Doxorubicin; Edetic Acid; Ethylenediamines; Ferric Compounds; Glycine; Hydrogen Peroxide; Hydrolysis; Hydroxides; Hydroxyl Radical; Iron; Kinetics; Oxidation-Reduction; Paraquat; Razoxane; Superoxides; Thiobarbituric Acid Reactive Substances; Xanthine Oxidase | 1993 |