Page last updated: 2024-08-24

ranolazine and simvastatin

ranolazine has been researched along with simvastatin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdallah, H; Chu, N; Huan, BL; Hussein, Z; Jerling, M; Leung, K1
Rifkin, SI1
Ezekiel, TO; Hylton, AC1
Kassardjian, CD; Milone, M; Tian, X; Vladutiu, G; Wong, LJ1

Reviews

1 review(s) available for ranolazine and simvastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for ranolazine and simvastatin

ArticleYear
Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:4

    Topics: Acetanilides; Adolescent; Adult; Diltiazem; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Ketoconazole; Male; Middle Aged; Piperazines; Ranolazine; Simvastatin

2005

Other Studies

5 other study(ies) available for ranolazine and simvastatin

ArticleYear
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: a case report.
    Medscape journal of medicine, 2008, Volume: 10, Issue:11

    Topics: Acetanilides; Adrenergic alpha-Antagonists; Calcium Channel Blockers; Carbazoles; Carvedilol; Diltiazem; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Transplantation; Male; Middle Aged; Piperazines; Propanolamines; Ranolazine; Rhabdomyolysis; Simvastatin

2008
Rhabdomyolysis in a patient receiving ranolazine and simvastatin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2010, Nov-01, Volume: 67, Issue:21

    Topics: Acetanilides; Angina Pectoris; Creatine Kinase; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Male; Middle Aged; Piperazines; Ranolazine; Rhabdomyolysis; Simvastatin

2010
Myopathy during treatment with the antianginal drug ranolazine.
    Journal of the neurological sciences, 2014, Dec-15, Volume: 347, Issue:1-2

    Topics: Acetanilides; Angina Pectoris; Anticholesteremic Agents; Biopsy; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Middle Aged; Muscular Diseases; Piperazines; Ranolazine; Simvastatin; Treatment Outcome

2014