ramiprilat and trandolapril

ramiprilat has been researched along with trandolapril* in 1 studies

Other Studies

1 other study(ies) available for ramiprilat and trandolapril

Article	Year
Evidence for two binding sites on membrane-bound angiotensin-converting enzymes (ACE) for exogenous inhibitors except in testis. Life sciences, 1992, Volume: 51, Issue:10 It was possible to assess that ACE inhibitors bound to two different sites on the enzymes which consist in two homologous domains. Accordingly, it was also shown that testis ACE which consists in a single domain exhibits only one site for inhibitors. The common binding site of both enzymes contains Zn2+, bears the enzymatic activity, is less sensitive to added Zn2+ and Cl- and has a lower affinity for inhibitors than the first one, found only in duplicated domain enzymes and highly sensitive to the effect of ions. Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Brain; Captopril; Cell Membrane; Indoles; Lung; Male; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Testis	1992

Article

Year

Evidence for two binding sites on membrane-bound angiotensin-converting enzymes (ACE) for exogenous inhibitors except in testis.

Life sciences, 1992, Volume: 51, Issue:10

It was possible to assess that ACE inhibitors bound to two different sites on the enzymes which consist in two homologous domains. Accordingly, it was also shown that testis ACE which consists in a single domain exhibits only one site for inhibitors. The common binding site of both enzymes contains Zn2+, bears the enzymatic activity, is less sensitive to added Zn2+ and Cl- and has a lower affinity for inhibitors than the first one, found only in duplicated domain enzymes and highly sensitive to the effect of ions.

Topics: Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Brain; Captopril; Cell Membrane; Indoles; Lung; Male; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Rats; Rats, Inbred Strains; Testis

1992