Compounds > ramelteon
Page last updated: 2024-09-05

ramelteon and midazolam

ramelteon has been researched along with midazolam in 5 studies

Compound Research Comparison

Studies
(ramelteon)		Trials
(ramelteon)		Recent Studies (post-2010)
(ramelteon)		Studies
(midazolam)		Trials
(midazolam)		Recent Studies (post-2010) (midazolam)
317592049,8343,1913,301

Protein Interaction Comparison

ProteinTaxonomyramelteon (IC50)midazolam (IC50)
Cytochrome P450 3A4Homo sapiens (human)2.7427

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cruź, CM; France, CP; Koek, W; McMahon, LR; Weltman, RH1
Brodney, MA; Obach, RS; Walker, GS1
Iba, Y; Kimura, T; Murai, H; Suzuki, H; Tanji, H1

Reviews

1 review(s) available for ramelteon and midazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for ramelteon and midazolam

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Acute and chronic effects of ramelteon in rhesus monkeys (Macaca mulatta): dependence liability studies.
    Behavioral neuroscience, 2006, Volume: 120, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Benzodiazepines; Conditioning, Classical; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flumazenil; GABA Modulators; Hypnotics and Sedatives; Indenes; Macaca mulatta; Male; Methylcellulose; Midazolam; Neuropsychological Tests; Receptors, Melatonin; Substance-Related Disorders; Time Factors

2006
Biosynthesis of Fluorinated Analogs of Drugs Using Human Cytochrome P450 Enzymes Followed by Deoxyfluorination and Quantitative Nuclear Magnetic Resonance Spectroscopy to Improve Metabolic Stability.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:5

    Topics: Aldehydes; Celecoxib; Cytochrome P-450 Enzyme System; Diethylamines; Fluorine; Halogenation; Humans; Hydroxylation; Indenes; Magnetic Resonance Spectroscopy; Microsomes, Liver; Midazolam; Pharmaceutical Preparations; Risperidone

2016
A simple method using anesthetics to test effects of sleep-inducing substances in mice.
    Journal of pharmacological sciences, 2020, Volume: 142, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Azepines; Butorphanol; Chlorpromazine; Drug Combinations; Imidazoles; Indenes; Isoflurane; Male; Medetomidine; Mice; Mice, Inbred ICR; Midazolam; Orexin Receptor Antagonists; Sleep Aids, Pharmaceutical; Triazoles

2020