Page last updated: 2024-09-03

ramatroban and thromboxanes

ramatroban has been researched along with thromboxanes in 21 studies

Compound Research Comparison

Studies
(ramatroban)
Trials
(ramatroban)
Recent Studies (post-2010)
(ramatroban)
Studies
(thromboxanes)
Trials
(thromboxanes)
Recent Studies (post-2010) (thromboxanes)
14210283,202149199

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (90.48)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Darius, H; Meyer, J; Michael-Hepp, J1
Dellweg, H; Gross, R; Perzborn, E; Theis, JG1
Bardin, PG; Harrison, J; Holgate, ST; Johnston, SL; Joubert, JR; Ritter, W1
Cuthbert, NJ; Gardiner, PJ; McKenniff, MG; Norman, P3
Baunack, AR; Boerger, S; Magnussen, H; Templin, K1
Brink, C; Gardiner, PJ; Labat, C; Norel, X1
Francis, HP; Gardiner, PJ; Greenham, SJ; Patel, UP; Thompson, AM1
Fiedler, VB; Perzborn, E; Seuter, F4
Francis, HP; Gardiner, PJ; Morris, TG; Patel, UP; Thompson, AM1
Karasawa, A; Lefer, AM; Ma, XL1
Böshagen, H; Fiedler, VB; Perzborn, E; Rosentreter, U; Sander, E; Seuter, F; Stasch, JP; Weber, H1
Braun, M; Schrör, K1
Freezer, NJ; Howarth, PH; Johnston, SL; O'Toole, S; Ritter, W1
Mazar-Feldman, J; Rimon, G1
Makita, S; Sakairi, T; Shakuto, S; Suzuki, K; Wajima, T; Yaguchi, M; Yoshida, Y1
Abdelazeem, H; Aljesri, K; Norel, X; Ozen, G; Topal, G; Turkyılmaz, G; Turkyılmaz, S1

Trials

3 trial(s) available for ramatroban and thromboxanes

ArticleYear
The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations.
    British journal of clinical pharmacology, 1992, Volume: 34, Issue:5

    Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbazoles; Female; Histamine; Histamine Antagonists; Humans; Male; Middle Aged; Prostaglandin D2; Respiratory Function Tests; Sulfonamides; Thromboxanes

1992
Effects of a thromboxane-receptor antagonist, BAY u 3405, on prostaglandin D2- and exercise-induced bronchoconstriction.
    The Journal of allergy and clinical immunology, 1992, Volume: 89, Issue:6

    Topics: Air; Airway Resistance; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchoconstriction; Carbazoles; Cold Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Forced Expiratory Volume; Humans; Male; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxanes; Time Factors

1992
Prostaglandin D2-induced bronchoconstriction is mediated only in part by the thromboxane prostanoid receptor.
    The European respiratory journal, 1995, Volume: 8, Issue:3

    Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Carbazoles; Double-Blind Method; Forced Expiratory Volume; Humans; Male; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxanes

1995

Other Studies

18 other study(ies) available for ramatroban and thromboxanes

ArticleYear
Receptor binding properties of the new and specific thromboxane receptor antagonist Bay U 3405.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Binding, Competitive; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Fatty Acids, Unsaturated; Humans; Hydrazines; In Vitro Techniques; Kinetics; Membranes; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxanes

1992
pH-dependent binding of the TXA2/PGH2-receptor of human platelet membranes to various ligands.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Carbazoles; Cell Membrane; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ligands; Phenylacetates; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstrictor Agents

1992
The thromboxane receptors of rat and guinea-pig lung.
    European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Sulfonamides; Thromboxanes

1992
Inhibitory effects of BAY u3405 on prostanoid-induced contractions in human isolated bronchial and pulmonary arterial muscle preparations.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bronchi; Carbazoles; Histamine; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Artery; Sulfonamides; Thromboxanes

1991
BAY u3405 an antagonist of thromboxane A2- and prostaglandin D2-induced bronchoconstriction in the guinea-pig.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Aerosols; Animals; Blood Pressure; Bronchoconstriction; Carbazoles; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Serotonin; SRS-A; Sulfonamides; Thromboxane A2; Thromboxanes

1991
Effect of BAY U 3405, a new thromboxane antagonist, on arachidonic acid induced thromboembolism.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchoconstriction; Carbazoles; Death, Sudden; Dose-Response Relationship, Drug; Male; Platelet Aggregation; Rabbits; Sulfonamides; Survival Rate; Thromboembolism; Thromboxane A2; Thromboxanes

1991
The thromboxane receptor antagonist BAY u3405 reverses prostaglandin D2 (PGD2)-induced bronchoconstriction in the anaesthetised guinea pig.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: Animals; Bronchoconstriction; Carbazoles; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung Volume Measurements; Male; Prostaglandin D2; Receptors, Prostaglandin; Receptors, Thromboxane; Sotalol; Sulfonamides; Thromboxanes

1991
BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Ferrets; Guinea Pigs; Humans; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Stereoisomerism; Sulfonamides; Thromboxanes

1991
Mechanism of the protective action of Bay-u-3405, a new specific thromboxane receptor antagonist, in arachidonate-induced sudden death.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bronchi; Carbazoles; Death, Sudden; Electrocardiography; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Radioimmunoassay; Sulfonamides; Thromboxane A2; Thromboxanes

1991
BAY u3405 is a potent and competitive antagonist of U46619, PGD2 and 9 alpha, 11 beta PGF2 alpha-induced contractions of airway smooth muscle.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Thromboxanes; Trachea

1991
Protective effect of a novel thromboxane antagonist, BAY-U3405, on canine myocardial damage after coronary artery occlusion and reperfusion.
    Pharmacotherapy, 1991, Volume: 11, Issue:1

    Topics: Animals; Carbazoles; Coronary Circulation; Dogs; Female; Hemodynamics; Humans; Infusions, Intravenous; Ligation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Sulfonamides; Thromboxanes; Time Factors; Ventricular Fibrillation

1991
Characterization of Bay U 3405, a novel thromboxane A2/endoperoxide receptor antagonist.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Adenosine Diphosphate; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Carbazoles; Cerebrovascular Disorders; Collagen; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred SHR; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboembolism; Thromboxanes; Vasoconstriction

1990
Effect of Bay U 3405, a new thromboxane antagonist, on collagen-induced thromboembolism in rabbits.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: Animals; Blood Pressure; Carbazoles; Collagen; Electrocardiography; Heart Rate; Male; Rabbits; Sulfonamides; Thromboembolism; Thromboxanes

1990
Effects of the novel thromboxane antagonist Bay U 3405 on experimental coronary artery disease.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Hemodynamics; Myocardial Infarction; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Swine; Thromboxanes; Vasoconstriction

1990
Bay U 3405 inhibits cerebral vasospasm induced by authentic thromboxane A2.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Carbazoles; Cattle; Cerebral Arteries; Humans; Ischemic Attack, Transient; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstriction

1990
A common low-affinity binding site for primary prostanoids on bovine aortic endothelial cells.
    Cellular signalling, 1996, Volume: 8, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Binding Sites; Biphenyl Compounds; Carbazoles; Cattle; Cells, Cultured; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Endothelium, Vascular; Epoprostenol; Heptanoic Acids; Iloprost; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxanes; Xanthenes; Xanthones

1996
Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.
    Pharmacology, 2005, Volume: 75, Issue:2

    Topics: Airway Resistance; Animals; Anti-Allergic Agents; Area Under Curve; Carbazoles; Disease Models, Animal; Guinea Pigs; Indoles; Leukotrienes; Male; Ovalbumin; Phenylcarbamates; Pyrilamine; Rhinitis; Sulfonamides; Terfenadine; Thromboxanes; Tosyl Compounds

2005
Comparative study on the effect of aspirin, TP receptor antagonist and TxA
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Arachidonic Acid; Aspirin; Benzofurans; Carbazoles; Enzyme Inhibitors; Female; Humans; Male; Mammary Arteries; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Prostaglandin; Receptors, Thromboxane; Saphenous Vein; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

2021