Page last updated: 2024-09-03

ramatroban and thromboxane a2

ramatroban has been researched along with thromboxane a2 in 38 studies

Compound Research Comparison

Studies
(ramatroban)
Trials
(ramatroban)
Recent Studies (post-2010)
(ramatroban)
Studies
(thromboxane a2)
Trials
(thromboxane a2)
Recent Studies (post-2010) (thromboxane a2)
14210285,617224429

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19903 (7.89)18.7374
1990's27 (71.05)18.2507
2000's7 (18.42)29.6817
2010's0 (0.00)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Darius, H; Meyer, J; Michael-Hepp, J1
Dellweg, H; Gross, R; Perzborn, E; Theis, JG2
Francis, HP; Gardiner, PJ; Greenham, SJ; Patel, UP; Thompson, AM1
Fiedler, VB; Perzborn, E; Seuter, F1
Karasawa, A; Lefer, AM; Ma, XL1
Braun, M; Schrör, K1
Böshagen, H; Fiedler, VB; Perzborn, E; Rosentreter, U; Seuter, F3
Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Shigyo, M; Takata, S2
Arima, M; Fukuda, T; Makino, S; Yukawa, T1
Altavilla, D; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Sardella, A; Squadrito, F; Squadrito, G; Urna, G1
Itoh, Y1
Badenhorst, PN; Hundt, HK; Lötter, MG; Nel, CJ; Pieters, H; Roodt, JP; Schall, R; van Wyk, V1
Altavilla, D; Campo, GM; Canale, P; Caputi, AP; Faggiotto, A; Ioculano, M; Oriti, S; Saitta, A; Squadrito, F; Zingarelli, B1
Igarashi, A; Iijima, H; Inoue, H; Okada, S; Takishima, T; Tani, N1
Lucchesi, BR; Mu, DX; Rote, WE1
Inagaki, N; Matsuo, A; Nagai, H; Takeda, H; Tanaka, H; Yamaguchi, S1
Gundel, R; Jesmok, G1
Fujimura, M; Kasahara, K; Matsuda, T; Nakatsumi, Y; Nishi, K1
Akiyama, K; Endo, S1
Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Nakano, H1
Mazar-Feldman, J; Rimon, G1
Cui, ZH; Kawikova, I; Lötvall, J; Okazawa, A; Skoogh, BE1
Ahr, HJ; Beckermann, B; Boberg, M; Bühner, K; Hirayama, M; Siefert, HM; Steinke, W; Wünsche, C1
Ahr, HJ; Hirayama, M; Steinke, W1
Abbas, F; Amin, Z; Burk, RM; Krauss, AH; Marshall, K; Senior, J; Woodward, DF1
Diener, M; Schultheiss, G1
Diener, M; Frings, M; Haschke, G; Heinke, B; Schäfer, KH1
Fujisawa, C; Hironaka, T; Itakura, A; Kawamoto, K; Matsuda, H; Mitsuhashi, M; Sawada, S; Takaku, M; Tanaka, A1
Kamei, C; Kayasuga, R; Sugimoto, Y; Watanabe, T1
Benoit, P; de Leval, X; Delarge, J; Dogné, JM; Masereel, B1
Moriwaki, T; Yamamoto, A; Yasui, H1
Dogné, JM; Masereel, B; Rolin, S1
Jiang, S; Kamei, C; Kishi, Y; Nakano, Y; Yatsuzuka, R1
Abdelazeem, H; Aljesri, K; Norel, X; Ozen, G; Topal, G; Turkyılmaz, G; Turkyılmaz, S1

Reviews

3 review(s) available for ramatroban and thromboxane a2

ArticleYear
[Thromboxane A2 receptor antagonist in asthma therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1996, Volume: 54, Issue:11

    Topics: Asthma; Benzoquinones; Bridged Bicyclo Compounds; Bronchi; Bronchial Hyperreactivity; Carbazoles; Fatty Acids, Monounsaturated; Heptanoic Acids; Humans; Prostaglandins; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1996
Thromboxane A2 inhibition: therapeutic potential in bronchial asthma.
    American journal of respiratory medicine : drugs, devices, and other interventions, 2002, Volume: 1, Issue:1

    Topics: Anti-Asthmatic Agents; Asthma; Benzoquinones; Carbazoles; Heptanoic Acids; Humans; Methacrylates; Molecular Structure; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase

2002
Prostanoids as pharmacological targets in COPD and asthma.
    European journal of pharmacology, 2006, Mar-08, Volume: 533, Issue:1-3

    Topics: Animals; Asthma; Benzoquinones; Carbazoles; Enzyme Inhibitors; F2-Isoprostanes; Heptanoic Acids; Humans; Methacrylates; Prostaglandin Antagonists; Prostaglandin D2; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase

2006

Trials

2 trial(s) available for ramatroban and thromboxane a2

ArticleYear
Antithrombotic activity of Bay u3405, a thromboxane A2-antagonist, in patients with Dacron aortic grafts: a random controlled clinical trial.
    Thrombosis and haemostasis, 1993, Dec-20, Volume: 70, Issue:6

    Topics: Aged; Aorta; Blood Platelets; Blood Vessel Prosthesis; Carbazoles; Cell Survival; Double-Blind Method; Follow-Up Studies; Humans; Indium Radioisotopes; Male; Middle Aged; Platelet Adhesiveness; Polyethylene Terephthalates; Sulfonamides; Thromboxane A2

1993
Involvement of thromboxane A2 in bronchial hyperresponsiveness of asthma. Kanazawa Asthma Research Group.
    Pulmonary pharmacology, 1995, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Carbazoles; Cross-Over Studies; Double-Blind Method; Fatty Acids, Monounsaturated; Female; Forced Expiratory Volume; Humans; Male; Methacholine Chloride; Middle Aged; Prostaglandin Antagonists; Sulfonamides; Thromboxane A2

1995

Other Studies

33 other study(ies) available for ramatroban and thromboxane a2

ArticleYear
Receptor binding properties of the new and specific thromboxane receptor antagonist Bay U 3405.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Binding, Competitive; Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Fatty Acids, Unsaturated; Humans; Hydrazines; In Vitro Techniques; Kinetics; Membranes; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxanes

1992
pH-dependent binding of the TXA2/PGH2-receptor of human platelet membranes to various ligands.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Carbazoles; Cell Membrane; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ligands; Phenylacetates; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstrictor Agents

1992
Binding characteristics of the new thromboxane A2/prostaglandin H2 receptor antagonist [3H]BAY U 3405 to washed human platelets and platelet membranes.
    Biochemical pharmacology, 1992, Aug-04, Volume: 44, Issue:3

    Topics: Blood Platelets; Carbazoles; Cell Fractionation; Cell Membrane; Humans; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1992
BAY u3405 an antagonist of thromboxane A2- and prostaglandin D2-induced bronchoconstriction in the guinea-pig.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Aerosols; Animals; Blood Pressure; Bronchoconstriction; Carbazoles; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Serotonin; SRS-A; Sulfonamides; Thromboxane A2; Thromboxanes

1991
Effect of BAY U 3405, a new thromboxane antagonist, on arachidonic acid induced thromboembolism.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bronchoconstriction; Carbazoles; Death, Sudden; Dose-Response Relationship, Drug; Male; Platelet Aggregation; Rabbits; Sulfonamides; Survival Rate; Thromboembolism; Thromboxane A2; Thromboxanes

1991
Mechanism of the protective action of Bay-u-3405, a new specific thromboxane receptor antagonist, in arachidonate-induced sudden death.
    Methods and findings in experimental and clinical pharmacology, 1991, Volume: 13, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bronchi; Carbazoles; Death, Sudden; Electrocardiography; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Radioimmunoassay; Sulfonamides; Thromboxane A2; Thromboxanes

1991
Bay U 3405 inhibits cerebral vasospasm induced by authentic thromboxane A2.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Carbazoles; Cattle; Cerebral Arteries; Humans; Ischemic Attack, Transient; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstriction

1990
Synthesis and absolute configuration of the new thromboxane antagonist (3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-carbazolepropan oic acid and comparison with its enantiomer.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Chemical Phenomena; Chemistry; Humans; In Vitro Techniques; Molecular Conformation; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Stereoisomerism; Sulfonamides; Thromboxane A2

1989
Inhibition of platelet aggregation in vitro and ex vivo by the new thromboxane antagonist (3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9- carbazolepropanoic acid.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:12

    Topics: Animals; Carbazoles; Collagen; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Sulfonamides; Thromboxane A2

1989
Reduction of in vivo coronary artery thrombosis by the novel thromboxane antagonist (3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9- carbazolepropanoic acid.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:12

    Topics: Animals; Blood Pressure; Carbazoles; Coronary Circulation; Coronary Disease; Coronary Thrombosis; Dogs; Electric Stimulation; Female; Fibrinolytic Agents; Heart Rate; Humans; In Vitro Techniques; Male; Myocardial Infarction; Sulfonamides; Thromboxane A2

1989
Effect of BAY u3405, a thromboxane A2 receptor antagonist, on neuro-effector transmission in canine tracheal tissue.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 53, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Atropine; Carbazoles; Dogs; Electric Stimulation; Female; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Synaptic Transmission; Tetrodotoxin; Thromboxane A2; Trachea; Vagus Nerve; Vasoconstrictor Agents

1995
[Effect of BAY u3405-thromboxane A2 receptor antagonist, on biphasic airway responses induced by platelet-activating factor in actively sensitized guinea pigs].
    Arerugi = [Allergy], 1995, Volume: 44, Issue:7

    Topics: Airway Resistance; Animals; Carbazoles; Guinea Pigs; Male; Platelet Activating Factor; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Vaccination

1995
Beneficial effects of BAY u3405, a novel thromboxane A2 receptor antagonist, in splanchnic artery occlusion shock.
    Pharmacology, 1994, Volume: 49, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterial Occlusive Diseases; Blood Pressure; Carbazoles; Macrophages; Male; Myocardial Depressant Factor; Peroxidase; Phagocytosis; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Shock; Splanchnic Circulation; Sulfonamides; Survival Rate; Thromboxane A2; Thromboxane B2

1994
Blockade of thromboxane A2 receptor ameliorates delayed postischemic hypoperfusion of the brain in cats.
    The Keio journal of medicine, 1994, Volume: 43, Issue:2

    Topics: Animals; Carbazoles; Cats; Cerebrovascular Circulation; Ischemic Attack, Transient; Perfusion; Reaction Time; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1994
Reduction of myocardial leukocyte accumulation and myocardial infarct size following administration of BAY u3405, a thromboxane A2 receptor antagonist, in myocardial ischaemia-reperfusion injury.
    Agents and actions, 1993, Volume: 39, Issue:3-4

    Topics: Animals; Carbazoles; Creatine Kinase; Hemodynamics; Leukocytes; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1993
[Effect of thromboxane receptor antagonist, BAY u 3405 on the late phase pulmonary response in guinea pigs].
    Arerugi = [Allergy], 1993, Volume: 42, Issue:3 Pt 1

    Topics: Airway Resistance; Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbazoles; Guinea Pigs; Leukocyte Count; Lung; Male; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1993
Thromboxane antagonism in experimental canine carotid artery thrombosis.
    Stroke, 1993, Volume: 24, Issue:6

    Topics: Animals; Carbazoles; Carotid Artery Thrombosis; Disease Models, Animal; Dogs; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Sulfonamides; Thromboxane A2

1993
The effect of a thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions.
    Prostaglandins, 1995, Volume: 50, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Hyperreactivity; Carbazoles; Dermatitis; Guinea Pigs; Hypersensitivity; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1995
Thromboxane-blocked swine as an experimental model of severe intravascular inflammation and septic shock.
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Bronchoconstriction; Capillary Permeability; Carbazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Inflammation; Leukocytes; Leukopenia; Lung; Platelet Aggregation Inhibitors; Pulmonary Circulation; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha; Vasoconstriction

1995
Thromboxane A2 mimetic (U-46619) induces hyperresponsiveness of smooth muscle in the canine bronchiole, but not in the trachea.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bronchi; Carbazoles; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Trachea; Vasoconstrictor Agents

1996
Thromboxane A2 antagonist inhibits leukotriene D4-induced smooth muscle contraction in guinea-pig lung parenchyma, but not in trachea.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 55, Issue:6

    Topics: Animals; Carbazoles; Female; Guinea Pigs; Leukotriene D4; Lung; Male; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Sulfonamides; Thromboxane A2; Trachea

1996
A common low-affinity binding site for primary prostanoids on bovine aortic endothelial cells.
    Cellular signalling, 1996, Volume: 8, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Binding Sites; Biphenyl Compounds; Carbazoles; Cattle; Cells, Cultured; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Endothelium, Vascular; Epoprostenol; Heptanoic Acids; Iloprost; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxanes; Xanthenes; Xanthones

1996
8-Epi-PGF2alpha induces airflow obstruction and airway plasma exudation in vivo.
    American journal of respiratory and critical care medicine, 1997, Volume: 155, Issue:2

    Topics: Airway Obstruction; Animals; Bronchoalveolar Lavage Fluid; Carbazoles; Dinoprost; Guinea Pigs; Histamine Antagonists; Male; Methacrylates; Platelet Aggregation Inhibitors; Sulfonamides; Thromboxane A2; Thromboxane B2; Vasoconstrictor Agents

1997
Pharmacokinetics and metabolism of the new thromboxane A2 receptor antagonist ramatroban in animals. 1st communication: absorption, concentrations in plasma, metabolism, and excretion after single administration to rats and dogs.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:8

    Topics: Administration, Oral; Animals; Biological Availability; Biotransformation; Carbazoles; Chromatography, High Pressure Liquid; Dogs; Enterohepatic Circulation; Female; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Liver; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Rats; Rats, Wistar; Receptors, Thromboxane; Sex Characteristics; Species Specificity; Spectrophotometry, Ultraviolet; Sulfonamides; Thromboxane A2

1997
Pharmacokinetics and metabolism of the new thromboxane A2 receptor antagonist ramatroban in animals. 2nd communication: distribution to organs and tissues in male, female and pregnant rats, and characteristics of protein binding in plasma.
    Arzneimittel-Forschung, 1997, Volume: 47, Issue:8

    Topics: Administration, Oral; Animals; Area Under Curve; Autoradiography; Blood Proteins; Carbazoles; Dogs; Female; Injections, Intravenous; Male; Mice; Milk; Placenta; Pregnancy; Protein Binding; Rabbits; Rats; Rats, Wistar; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Tissue Distribution

1997
A comparative study of thromboxane (TP) receptor mimetics and antagonists on isolated human umbilical artery and myometrium.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Umbilical Arteries

1997
Inhibition of spontaneous smooth muscle contractions in rat and rabbit intestine by blockers of the thromboxane A2 pathway.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1999, Volume: 46, Issue:2

    Topics: Animals; Benzimidazoles; Benzoxepins; Carbachol; Carbazoles; Colon; Female; In Vitro Techniques; Indomethacin; Intestine, Small; Isometric Contraction; Male; Masoprocol; Muscle, Smooth; Rabbits; Rats; Rats, Wistar; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1999
Spontaneous contractions of intestinal smooth muscle re-aggregates from the new-born rat triggered by thromboxane A2.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2000, Volume: 47, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calcium; Carbachol; Carbazoles; Cell Aggregation; Cholinergic Agonists; Fluorescent Dyes; Fura-2; Intestine, Small; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Rats; Sulfonamides; Tetrodotoxin; Thromboxane A2; Vasoconstrictor Agents; Verapamil

2000
Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: dual activation of platelets and vascular endothelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Platelets; Carbazoles; Cells, Cultured; Dermatitis, Contact; Ear; Endothelium, Vascular; Humans; Immune Sera; Injections, Intradermal; Injections, Intraperitoneal; Injections, Intravenous; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Serotonin; Sulfonamides; Thromboxane A2; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents

2001
Participation of chemical mediators other than histamine in nasal allergy signs: a study using mice lacking histamine H(1) receptors.
    European journal of pharmacology, 2002, Aug-09, Volume: 449, Issue:3

    Topics: Animals; Anti-Allergic Agents; Antigens; Behavior, Animal; Carbazoles; Cetirizine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Immunization; Immunoglobulin E; Indicators and Reagents; Indoles; Leukotriene Antagonists; Mice; Mice, Knockout; Ovalbumin; Passive Cutaneous Anaphylaxis; Phenylcarbamates; Receptors, Histamine H1; Rhinitis, Allergic, Seasonal; Sneezing; Sulfonamides; Thromboxane A2; Tosyl Compounds

2002
Pharmacokinetic analysis of ramatroban using a recirculatory model with enterohepatic circulation by measuring portal and systemic blood concentration difference in Sprague-Dawley and Eisai hyperbilirubinemic rats.
    Pharmaceutical research, 2004, Volume: 21, Issue:6

    Topics: Administration, Oral; Animals; Animals, Genetically Modified; Bile; Carbazoles; Disease Models, Animal; Enterohepatic Circulation; Glucuronides; Hyperbilirubinemia; Injections, Intravenous; Membrane Transport Proteins; Metabolic Clearance Rate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2; Species Specificity; Sulfonamides; Thromboxane A2

2004
Participation in cysteinyl leukotrienes and thromboxane A2 in nasal congestion model in Brown Norway rats.
    International immunopharmacology, 2007, Volume: 7, Issue:11

    Topics: Animals; Benzoquinones; Carbazoles; Chromones; Dose-Response Relationship, Drug; Heptanoic Acids; Indoles; Leukotrienes; Male; Membrane Proteins; Phenylcarbamates; Rats; Rats, Inbred BN; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis; Sneezing; Sulfonamides; Thromboxane A2; Tosyl Compounds

2007
Comparative study on the effect of aspirin, TP receptor antagonist and TxA
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Arachidonic Acid; Aspirin; Benzofurans; Carbazoles; Enzyme Inhibitors; Female; Humans; Male; Mammary Arteries; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Prostaglandin; Receptors, Thromboxane; Saphenous Vein; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

2021