Page last updated: 2024-09-03

ramatroban and cay 10471

ramatroban has been researched along with cay 10471 in 2 studies

Compound Research Comparison

Studies (ramatroban)	Trials (ramatroban)	Recent Studies (post-2010) (ramatroban)	Studies (cay 10471)	Trials (cay 10471)	Recent Studies (post-2010) (cay 10471)
142	10	28	22	0	16

Protein Interaction Comparison

Protein	Taxonomy	ramatroban (IC50)	cay 10471 (IC50)
Prostaglandin D2 receptor 2	Homo sapiens (human)		0.0036

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kostenis, E; Ulven, T	1
Beaulieu, C; Berthelette, C; Colucci, J; Crackower, MA; Dalton, C; Denis, D; Ducharme, Y; Friesen, RW; Gallant, M; Gervais, FG; Guay, D; Hamel, M; Houle, R; Kosjek, B; Krawczyk, CM; Lau, S; Leblanc, Y; Lee, EE; Levesque, JF; Mellon, C; Molinaro, C; Mullet, W; O'Neill, GP; O'Shea, P; Sawyer, N; Sillaots, S; Simard, D; Slipetz, D; Stocco, R; Sørensen, D; Truong, VL; Wang, Z; Wong, E; Wu, J; Zaghdane, H	1

Studies

Kostenis, E; Ulven, T

Beaulieu, C; Berthelette, C; Colucci, J; Crackower, MA; Dalton, C; Denis, D; Ducharme, Y; Friesen, RW; Gallant, M; Gervais, FG; Guay, D; Hamel, M; Houle, R; Kosjek, B; Krawczyk, CM; Lau, S; Leblanc, Y; Lee, EE; Levesque, JF; Mellon, C; Molinaro, C; Mullet, W; O'Neill, GP; O'Shea, P; Sawyer, N; Sillaots, S; Simard, D; Slipetz, D; Stocco, R; Sørensen, D; Truong, VL; Wang, Z; Wong, E; Wu, J; Zaghdane, H

Other Studies

2 other study(ies) available for ramatroban and cay 10471

Article	Year
Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist. Journal of medicinal chemistry, 2005, Feb-24, Volume: 48, Issue:4 Topics: Anti-Allergic Agents; Arrestins; beta-Arrestins; Binding, Competitive; Carbazoles; Cyclic AMP; Energy Transfer; Inositol Phosphates; Luminescent Measurements; Molecular Conformation; Protein Transport; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Structure-Activity Relationship; Sulfonamides	2005
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases. Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1 Topics: Animals; Carbolines; Humans; Lung Diseases; Macaca mulatta; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship	2011

Article

Year

Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist.

Journal of medicinal chemistry, 2005, Feb-24, Volume: 48, Issue:4

Topics: Anti-Allergic Agents; Arrestins; beta-Arrestins; Binding, Competitive; Carbazoles; Cyclic AMP; Energy Transfer; Inositol Phosphates; Luminescent Measurements; Molecular Conformation; Protein Transport; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Structure-Activity Relationship; Sulfonamides

2005

Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.

Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

Topics: Animals; Carbolines; Humans; Lung Diseases; Macaca mulatta; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Structure-Activity Relationship

2011