Page last updated: 2024-09-03

ramatroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ramatroban has been researched along with 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid in 24 studies

Compound Research Comparison

Studies
(ramatroban)
Trials
(ramatroban)
Recent Studies (post-2010)
(ramatroban)
Studies
(15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid)
Trials
(15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid)
Recent Studies (post-2010) (15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid)
14210282,57727327

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's16 (66.67)18.2507
2000's7 (29.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dellweg, H; Gross, R; Perzborn, E; Theis, JG1
Cuthbert, NJ; Gardiner, PJ; McKenniff, MG; Norman, P3
Brink, C; Gardiner, PJ; Labat, C; Norel, X1
Francis, HP; Gardiner, PJ; Greenham, SJ; Patel, UP; Thompson, AM1
Fiedler, VB; Perzborn, E; Seuter, F1
Braun, M; Schrör, K1
Böshagen, H; Fiedler, VB; Perzborn, E; Rosentreter, U; Seuter, F1
Aizawa, H; Hara, N; Inoue, H; Koto, H; Matsumoto, K; Shigyo, M; Takata, S2
Inagaki, N; Matsuo, A; Nagai, H; Takeda, H; Tanaka, H; Yamaguchi, S1
Mazar-Feldman, J; Rimon, G1
Abbas, F; Amin, Z; Burk, RM; Krauss, AH; Marshall, K; Senior, J; Woodward, DF1
Bouskela, E; Lavielle, G; Vallez, MO; Verbeuren, TJ1
Albors, M; Bioque, G; Carretero, M; Díaz Ricart, M; Escolar, G; Garrido, M; Ordinas, A1
Biella, G; Buccellati, C; de Curtis, M; Folco, G1
Diener, M; Frings, M; Haschke, G; Heinke, B; Schäfer, KH1
Fujisawa, C; Hironaka, T; Itakura, A; Kawamoto, K; Matsuda, H; Mitsuhashi, M; Sawada, S; Takaku, M; Tanaka, A1
Brink, C; de Montpreville, V; Norel, X; Walch, L1
Imagawa, W; Motobayashi, Y; Saida, K1
Böhm, E; Heinemann, A; Kollroser, M; McNamee, A; Pease, JE; Peskar, BA; Sandig, H; Shichijo, M; Sturm, GJ; Weiglhofer, I1
Bacon, KB; Okano, M; Shichijo, M; Sugimoto, H1
Feletou, M; Jensen, BL; Leung, GP; Man, RY; Skott, O; Tang, EH; Vanhoutte, PM1

Reviews

1 review(s) available for ramatroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
[Ramatroban (Baynas): a review of its pharmacological and clinical profile].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Animals; Capillary Permeability; Carbazoles; Clinical Trials as Topic; Humans; Nasal Cavity; Nasal Mucosa; Nasal Obstruction; Receptors, Thromboxane; Rhinitis, Allergic, Perennial; Sulfonamides

2001

Other Studies

23 other study(ies) available for ramatroban and 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid

ArticleYear
pH-dependent binding of the TXA2/PGH2-receptor of human platelet membranes to various ligands.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Carbazoles; Cell Membrane; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Ligands; Phenylacetates; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Receptors, Prostaglandin; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstrictor Agents

1992
The thromboxane receptors of rat and guinea-pig lung.
    European journal of pharmacology, 1992, Dec-15, Volume: 229, Issue:2-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Sulfonamides; Thromboxanes

1992
Inhibitory effects of BAY u3405 on prostanoid-induced contractions in human isolated bronchial and pulmonary arterial muscle preparations.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bronchi; Carbazoles; Histamine; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Artery; Sulfonamides; Thromboxanes

1991
BAY u3405 an antagonist of thromboxane A2- and prostaglandin D2-induced bronchoconstriction in the guinea-pig.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Oral; Aerosols; Animals; Blood Pressure; Bronchoconstriction; Carbazoles; Guinea Pigs; Histamine; In Vitro Techniques; Injections, Intravenous; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Serotonin; SRS-A; Sulfonamides; Thromboxane A2; Thromboxanes

1991
BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Ferrets; Guinea Pigs; Humans; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Prostaglandin; Receptors, Thromboxane; Species Specificity; Stereoisomerism; Sulfonamides; Thromboxanes

1991
BAY u3405 is a potent and competitive antagonist of U46619, PGD2 and 9 alpha, 11 beta PGF2 alpha-induced contractions of airway smooth muscle.
    Annals of the New York Academy of Sciences, 1991, Volume: 629

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Dinoprost; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Thromboxanes; Trachea

1991
Effects of the novel thromboxane antagonist Bay U 3405 on experimental coronary artery disease.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Hemodynamics; Myocardial Infarction; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Swine; Thromboxanes; Vasoconstriction

1990
Bay U 3405 inhibits cerebral vasospasm induced by authentic thromboxane A2.
    Stroke, 1990, Volume: 21, Issue:12 Suppl

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Platelets; Carbazoles; Cattle; Cerebral Arteries; Humans; Ischemic Attack, Transient; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sulfonamides; Thromboxane A2; Thromboxanes; Vasoconstriction

1990
Synthesis and absolute configuration of the new thromboxane antagonist (3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-carbazolepropan oic acid and comparison with its enantiomer.
    Arzneimittel-Forschung, 1989, Volume: 39, Issue:12

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Chemical Phenomena; Chemistry; Humans; In Vitro Techniques; Molecular Conformation; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Rabbits; Stereoisomerism; Sulfonamides; Thromboxane A2

1989
Effect of BAY u3405, a thromboxane A2 receptor antagonist, on neuro-effector transmission in canine tracheal tissue.
    Prostaglandins, leukotrienes, and essential fatty acids, 1995, Volume: 53, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Atropine; Carbazoles; Dogs; Electric Stimulation; Female; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Synaptic Transmission; Tetrodotoxin; Thromboxane A2; Trachea; Vagus Nerve; Vasoconstrictor Agents

1995
The effect of a thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions.
    Prostaglandins, 1995, Volume: 50, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bronchial Hyperreactivity; Carbazoles; Dermatitis; Guinea Pigs; Hypersensitivity; Immunoglobulin E; Male; Mice; Mice, Inbred BALB C; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Thromboxane A2

1995
Thromboxane A2 mimetic (U-46619) induces hyperresponsiveness of smooth muscle in the canine bronchiole, but not in the trachea.
    Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Bronchi; Carbazoles; Dogs; Female; Male; Muscle Contraction; Muscle, Smooth; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Trachea; Vasoconstrictor Agents

1996
A common low-affinity binding site for primary prostanoids on bovine aortic endothelial cells.
    Cellular signalling, 1996, Volume: 8, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Binding Sites; Biphenyl Compounds; Carbazoles; Cattle; Cells, Cultured; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Endothelium, Vascular; Epoprostenol; Heptanoic Acids; Iloprost; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Sulfonamides; Thromboxane A2; Thromboxanes; Xanthenes; Xanthones

1996
A comparative study of thromboxane (TP) receptor mimetics and antagonists on isolated human umbilical artery and myometrium.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Fatty Acids, Unsaturated; Female; Humans; Hydrazines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Myometrium; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Umbilical Arteries

1997
Activation of thromboxane receptors and the induction of vasomotion in the hamster cheek pouch microcirculation.
    British journal of pharmacology, 1997, Volume: 122, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arterioles; Carbazoles; Cheek; Cricetinae; Dose-Response Relationship, Drug; Heptanoic Acids; In Vitro Techniques; Male; Mesocricetus; Microcirculation; Nitric Oxide Synthase; Nitroarginine; Phenylephrine; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents

1997
Inhibition of platelet-vessel wall interactions by thromboxane receptor antagonism in a human in vitro system: potentiation of antiplatelet effects of aspirin.
    European journal of clinical investigation, 1998, Volume: 28, Issue:7

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Aspirin; Blood Platelets; Carbazoles; Drug Synergism; Endothelium, Vascular; Humans; In Vitro Techniques; Perfusion; Platelet Aggregation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Sulfonamides

1998
Simultaneous investigation of the neuronal and vascular compartments in the guinea pig brain isolated in vitro.
    Brain research. Brain research protocols, 1998, Volume: 3, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Basilar Artery; Brain; Carbazoles; Cell Compartmentation; Cerebrovascular Circulation; Cortical Spreading Depression; Guinea Pigs; Ketanserin; Membrane Potentials; Neurons; Organ Culture Techniques; Perfusion; Platelet Aggregation Inhibitors; Serotonin Antagonists; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents

1998
Spontaneous contractions of intestinal smooth muscle re-aggregates from the new-born rat triggered by thromboxane A2.
    Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 2000, Volume: 47, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calcium; Carbachol; Carbazoles; Cell Aggregation; Cholinergic Agonists; Fluorescent Dyes; Fura-2; Intestine, Small; Microscopy, Fluorescence; Muscle Contraction; Muscle, Smooth; Platelet Aggregation Inhibitors; Rats; Sulfonamides; Tetrodotoxin; Thromboxane A2; Vasoconstrictor Agents; Verapamil

2000
Necessity of thromboxane A2 for initiation of platelet-mediated contact sensitivity: dual activation of platelets and vascular endothelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2001, Jan-01, Volume: 166, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; Aorta, Abdominal; Aorta, Thoracic; Blood Platelets; Carbazoles; Cells, Cultured; Dermatitis, Contact; Ear; Endothelium, Vascular; Humans; Immune Sera; Injections, Intradermal; Injections, Intraperitoneal; Injections, Intravenous; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Platelet Activation; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Serotonin; Sulfonamides; Thromboxane A2; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents

2001
Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins.
    British journal of pharmacology, 2001, Volume: 134, Issue:8

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Carbazoles; Culture Techniques; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Iloprost; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Prostaglandins F, Synthetic; Pulmonary Veins; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Xanthenes; Xanthones

2001
11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils.
    The Journal of biological chemistry, 2004, Feb-27, Volume: 279, Issue:9

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Basophils; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Carbazoles; Cell Size; Chemotaxis, Leukocyte; Enzyme Inhibitors; Eosinophils; Fatty Acids, Unsaturated; Flow Cytometry; Humans; Hydrazines; Pertussis Toxin; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides; Thromboxane B2; Transfection; Type C Phospholipases

2004
CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.
    European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Carbazoles; Cell Line; Cell Movement; Cyclic AMP; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; Hydrazines; Indomethacin; Models, Biological; Pentanoic Acids; Prostaglandin D2; Pyridines; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides; Transfection; Tritium

2005
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats.
    Cardiovascular research, 2008, Apr-01, Volume: 78, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Immunohistochemistry; Naphthalenes; Phenylephrine; Potassium Chloride; Propionates; Prostaglandin Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Xanthones

2008