raloxifene hydrochloride has been researched along with transforming growth factor beta in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bryant, HU; Galvin, RJ; Glasebrook, AL; Hardikar, S; Sato, M; Termine, JD; Yang, NN | 1 |
| Glasebrook, A; Hardikar, S; Venugopalan, M; Yang, NN | 2 |
| Pennisi, E | 1 |
| Raisz, LG | 1 |
| Bryant, HU; Cho, S; Dodge, JA; Frolik, CA; Glasebrook, AL; Lugar, CW; Martin, MJ; Osborne, JJ; Phillips, DL; Sato, M; Short, LL; Spangle, LA; Yang, NN | 1 |
| Adrian, MD; Bryant, HU; Cole, HW; Fuson, TR; Glasebrook, AL; Grese, TA; Magee, DE; Pennington, LD; Phillips, DL; Rowley, ER; Sato, M; Shetler, PK; Short, LL; Sluka, JP; Venugopalan, M; Yang, NN | 1 |
| Bryant, HU; Fukuyama, T; Nakazawa, T | 1 |
| Choi, YK; Chung, HY; Han, IK; Han, KO; Hwang, CS; Jang, HC; Kang, YS; Moon, IG; Yim, CH; Yoon, HK | 1 |
| de la Piedra, C; García-Moreno, C; Méndez-Dávila, C; Turbì, C | 1 |
| Narayana Murthy, PS; Sengupta, S; Sharma, S; Singh, MM | 1 |
| Cano, A; García-Pérez, MÁ; Hermenegildo, C; Pineda, B; Tarín, JJ | 1 |
| Peek, GW; Tollefsbol, TO | 1 |
| Bu, X; Chen, D; Feng, Y; Liu, Z; Qin, W; Shao, W; Su, H; Wang, Y; Zhou, B | 1 |
| Hioki, T; Kozawa, O; Matsushima-Nishiwaki, R; Tokuda, H | 1 |
| Babaahmadi-Rezaei, H; Mohammadtaghvaei, N; Rashidi, M; Zarezade, V | 1 |
1 review(s) available for raloxifene hydrochloride and transforming growth factor beta
| Article | Year |
|---|---|
[Raloxifene mimics the effect of estrogen on bone].
Topics: Animals; Bone and Bones; Bone Density; Drug Design; Estrogens; Humans; Interleukin-6; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Transforming Growth Factor beta | 2000 |
1 trial(s) available for raloxifene hydrochloride and transforming growth factor beta
| Article | Year |
|---|---|
Effects of administration of hormone therapy or raloxifene on the immune system and on biochemical markers of bone remodeling.
Topics: Bone Density Conservation Agents; Bone Remodeling; Cell Proliferation; Cells, Cultured; Female; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1beta; Interleukin-4; Interleukin-6; Leukocytes, Mononuclear; Lymphocyte Subsets; Middle Aged; Osteoporosis, Postmenopausal; Osteoprotegerin; Raloxifene Hydrochloride; Receptor Activator of Nuclear Factor-kappa B; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2012 |
14 other study(ies) available for raloxifene hydrochloride and transforming growth factor beta
| Article | Year |
|---|---|
Estrogen and raloxifene stimulate transforming growth factor-beta 3 gene expression in rat bone: a potential mechanism for estrogen- or raloxifene-mediated bone maintenance.
Topics: Animals; Base Sequence; Bone and Bones; Cell Differentiation; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation; Molecular Sequence Data; Osteoclasts; Ovariectomy; Piperidines; Promoter Regions, Genetic; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transfection; Transforming Growth Factor beta | 1996 |
Identification of an estrogen response element activated by metabolites of 17beta-estradiol and raloxifene.
Topics: Base Sequence; Estradiol; Estrogen Antagonists; Gene Expression Regulation; Genes, Reporter; Humans; Ligands; Molecular Sequence Data; Piperidines; Promoter Regions, Genetic; Raloxifene Hydrochloride; Receptors, Estrogen; Transfection; Transforming Growth Factor beta; Tumor Cells, Cultured | 1996 |
Drug's link to genes reveals estrogen's many sides.
Topics: Bone and Bones; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Humans; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Regulatory Sequences, Nucleic Acid; Transforming Growth Factor beta; Uterus | 1996 |
Estrogen and bone: new pieces to the puzzle.
Topics: Animals; Bone Resorption; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Humans; Mice; Osteoblasts; Osteoclasts; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Tamoxifen; Transforming Growth Factor beta | 1996 |
Correction: raloxifene response needs more than an element.
Topics: Estrogen Antagonists; Gene Expression Regulation; Humans; Piperidines; Promoter Regions, Genetic; Raloxifene Hydrochloride; Transforming Growth Factor beta | 1997 |
Evaluation of the major metabolites of raloxifene as modulators of tissue selectivity.
Topics: Adenocarcinoma; Animals; Bone Resorption; Breast Neoplasms; Cell Division; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; Glucuronates; Humans; Interleukin-6; Organ Specificity; Osteoclasts; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tissue Distribution; Transforming Growth Factor beta; Tumor Cells, Cultured | 1997 |
Synthesis and pharmacology of conformationally restricted raloxifene analogues: highly potent selective estrogen receptor modulators.
Topics: Animals; Bone Density; Cell Division; Cholesterol; Estrogen Antagonists; Female; Gene Expression Regulation; HeLa Cells; Humans; Models, Molecular; Molecular Conformation; Naphthoquinones; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Transforming Growth Factor beta; Tumor Cells, Cultured; Uterus | 1998 |
Identification of a mutation in the human raloxifene response element of the transforming growth factor-beta 3 gene.
Topics: Estrogen Antagonists; Female; Humans; Middle Aged; Mutation; Raloxifene Hydrochloride; Response Elements; Transfection; Transforming Growth Factor beta | 2001 |
Effects of 17beta-estradiol, tamoxifen and raloxifene on the protein and mRNA expression of interleukin-6, transforming growth factor-beta1 and insulin-like growth factor-1 in primary human osteoblast cultures.
Topics: Aged; Antineoplastic Agents, Hormonal; Cell Culture Techniques; Estradiol; Estrogen Antagonists; Female; Humans; Insulin-Like Growth Factor I; Interleukin-6; Middle Aged; Osteoblasts; Osteoporosis; Postmenopause; Raloxifene Hydrochloride; RNA, Messenger; Tamoxifen; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Effect of ormeloxifene on ovariectomy-induced bone resorption, osteoclast differentiation and apoptosis and TGF beta-3 expression.
Topics: Animals; Apoptosis; Benzopyrans; Bone Density; Bone Marrow Cells; Bone Resorption; Calcium; Cell Differentiation; Cells, Cultured; Female; Lumbar Vertebrae; Mice; Mice, Inbred BALB C; Organ Size; Osteoclasts; Ovariectomy; Phosphorus; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta3; Uterus | 2006 |
Down-regulation of hTERT and Cyclin D1 transcription via PI3K/Akt and TGF-β pathways in MCF-7 Cancer cells with PX-866 and Raloxifene.
Topics: Axin Protein; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gonanes; Humans; Immunoblotting; MCF-7 Cells; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Raloxifene Hydrochloride; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad Proteins; Telomerase; Transcription, Genetic; Transforming Growth Factor beta | 2016 |
Raloxifene alleviates amyloid-β-induced cytotoxicity in HT22 neuronal cells via inhibiting oligomeric and fibrillar species formation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Survival; Gene Expression; Hydrophobic and Hydrophilic Interactions; Mice; Microglia; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Domains; Raloxifene Hydrochloride; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2019 |
Selective estrogen receptor modulators, acting as agonists of estrogen receptor α in osteoblasts, reduce the TGF-β-induced synthesis of macrophage colony-stimulating factor via inhibition of JNK signaling pathway.
Topics: Estrogen Receptor alpha; JNK Mitogen-Activated Protein Kinases; Macrophage Colony-Stimulating Factor; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Transforming Growth Factor beta | 2022 |
Cardioprotective effect of tamoxifen and raloxifene: Preventing proteoglycan synthesis by modulating non-canonical TGF-β signalling through NADPH oxidase and ERK phosphorylation.
Topics: Atherosclerosis; Humans; NADPH Oxidases; Phosphorylation; Proteoglycans; Raloxifene Hydrochloride; Reactive Oxygen Species; RNA, Messenger; Selective Estrogen Receptor Modulators; Tamoxifen; Transforming Growth Factor beta | 2023 |