Page last updated: 2024-08-23

raloxifene hydrochloride and thiophenes

raloxifene hydrochloride has been researched along with thiophenes in 80 studies

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.75)18.7374
1990's4 (5.00)18.2507
2000's43 (53.75)29.6817
2010's25 (31.25)24.3611
2020's5 (6.25)2.80

Authors

AuthorsStudies
Boundy, V; Komm, BS; Lyttle, CR; Sundstrom, SA; Xu, Q1
Jordan, VC1
Green, LR; Newboult, E; Valcaccia, B; Wakeling, AE1
Valcaccia, B; Wakeling, AE1
Bryan, N; Zuckerman, SH1
Adrian, MD; Bryant, HU; Rowley, E; Sato, M; Turner, CH; Wang, T1
Bernardi, F; Genazzani, AD; Genazzani, AR; Giardina, L; Luisi, M; Luisi, S; Monteleone, P; Petraglia, F; Rubino, S; Stomati, M1
Berg, DT; Calnek, DS; Ciaccia, AV; Grinnell, BW; Joyce, DE; Richardson, MA1
Bernardi, F; Casarosa, E; Farzati, A; Genazzani, AR; Luisi, M; Luisi, S; Monteleone, P; Petraglia, F; Rubino, S; Stomati, M1
Galid, A; Kubista, E; Seifert, M1
Carlsten, H; Erlandsson, MC; Gömöri, E; Taube, M1
Anderson, PW; Barrett-Connor, E; Cox, DA; Harper, K; Mosca, L; O'Gorman, J; Sarkar, S1
Adachi, K; Hayakawa, J; Hisamoto, K; Kanda, Y; Mabuchi, S; Miyamoto, Y; Murata, Y; Nishio, Y; Ohmichi, M; Takahashi, K; Taniguchi, N; Tasaka, K1
Elit, L; Hirte, H1
Gajdos, C; Jordan, VC1
Bethea, CL; Michelson, D; Mirkes, SJ; Su, A1
Chan, S1
Cox, DA; Hurn, PD; Littleton-Kearney, MT; Ostrowski, NL; Rossberg, MI1
Islamov, R; McMurray, R; Murashov, AK1
Fried, A; Segev, E; Wientroub, S; Zeitlin, L1
Balaguer, P; Bonnet, S; Cavaillès, V; Duong, V; Escande, A; Margueron, R; Vignon, F1
Barone, G; Bollati, A; Bonfanti, C; Burattin, A; Cozzi, R; Giustina, A; Poiesi, C; Tulipano, G; Turazzi, S; Valle, D1
Sporn, MB1
Li, J; Liu, B; Wang, M; Wu, X; Xie, Y; Xu, G; Yan, X; Yang, C1
David, E; Fournier dit Chabert, J; Lemaire, M; Pellet-Rostaing, S; Perrin, J1
Aknin, C; Chalbos, D; Freiss, G; Galtier, F; Maudelonde, T; Puech, C; Vignon, F1
Johansen, AM1
Benjamins, JA; Deighton-Collins, S; Guzmán, CB; Kleerekoper, M; Martinez, A; Skafar, DF; Zhao, C1
Clarke, R; Dai, P; Lou, MA; Lu, JF; Nazarov, V; Wong, LJ1
Kleerekoper, M1
Kaji, H; Sugimoto, T1
Kendler, D1
Roux, C1
Barna, A; Bourgoin, M; Briot, K; Chapurlat, R; Christin-Maitre, S; Cortet, B; Costagliola, D; Diebolt, V; Dumarcet, N; Lacoin, F; Letombe, B; Nouyrigat, E; Oberlin, F; Orcel, P; Ravaud, P; Roux, C; Seret, P; Thomas, T; Veyries, ML; Vogel, JY; Yoldjian, I1
Cremers, S; Garnero, P1
Cherkas, LF; Richards, JB; Spector, TD1
Cooperwood, JS; Khan, MO; Musa, MA1
Bolton, JL; Liu, H; Qin, Z; Thatcher, GR1
Mukherjee, A; Mukherjee, S; Mullick, S; Nagar, S; Saha, A1
Asghodom, RT; Bolton, JL; Frasor, J; Kastrati, I; Lantvit, DD; Overk, CR; Peng, KW; Qin, Z; Thatcher, GR1
Bolton, JL; Dietz, BM; Dunlap, T; Kastrati, I; Lantvit, DD; Overk, CR; Qin, Z; Thatcher, GR; Yao, P; Yu, B1
Inoue, D1
Rizzoli, R1
Carlsten, H; Islander, U; Jochems, C; Kallkopf, A; Lagerquist, M; Ohlsson, C1
Akishita, M; Eto, M; Kozaki, K; Okabe, T; Ouchi, Y; Yu, J1
Laroche, M1
Bolton, JL; Edirisinghe, P; Qin, Z; Thatcher, GR; Wijewickrama, GT; Yu, B1
Carlsten, H; Engdahl, C; Gustafsson, JA; Jochems, C; Lagerquist, MK; van der Saag, PT1
Ahmet-Camcioglu, N; Durmus-Altun, G; Ekuklu, G; Kucuk, M; Okman-Kilic, T1
Cox, DA; Downs, RW; Dowsett, SA; Ghosh, A; Harper, K; Moffett, AM1
Lewiecki, EM1
Mosekilde, L; Pinholt, EM; Rejnmark, L; Schwartz, K; Vestergaard, P2
Abe, Y; Irie, T; Iwasaki, N; Komatsu, M; Majima, T; Minami, A; Takahata, M1
Berthelot, JM; Glémarec, J; Guillot, P; Le Goff, B; Maugars, Y1
Brandi, ML1
Mosekilde, L; Rejnmark, L; Schwartz, F; Vestergaard, P1
Alam, J; Cox, DA; Dowsett, SA; Kendler, DL; Palacios, S; Stock, J; Zanchetta, J1
Arun, B; Brown, PH; Castiglione, M; Cuzick, J; DeCensi, A; Dunn, B; Forbes, JF; Glaus, A; Howell, A; Vogel, V; von Minckwitz, G; Zwierzina, H1
Landfeldt, E; Lang, A; Robbins, S; Ström, O1
Gitlin, M; Jick, S; Li, L; Roddam, A; Shearer, A; Shepherd, S; Taylor, A1
Alam, J; Bhattoa, HP; Cox, DA; Dowsett, SA; Goldstein, SR; Muram, D; Neven, P; Sipos, A1
Bolton, JL; Chandrasena, ER; Choi, J; Edirisinghe, PD; Hemachandra, LP; Kastrati, I; Thatcher, GR; Wang, YT1
Abbas-Chorfa, F; Ambrosi, V; Caillet, P; Chapurlat, R; Jaglal, SB; Reymondier, A; Schott, AM1
Cuzick, J; Sestak, I1
Briongos, L; Dueñas-Laita, A; García-Alonso, M; Pérez-Castrillón, JL; Ruiz-Mambrilla, M; Sañudo, S1
Lopez-Picado, A; Mendoza-Edroso, C; Sánchez Garrido-Lestache, N1
Gallo-Padilla, D; Gallo-Vallejo, JL1
Bolton, JL; Chandrasena, RE; Choi, J; Hemachandra, LP; Michalsen, BT; Patel, H; Piyankarage, SC; Scism, RA; Siklos, MI; Thatcher, GR; Thayer, EN; Wang, S; Wang, Y; Xiong, R1
Bouvet, A; Caruba, T; Pouchot, J; Sabatier, B; Savoldelli, V1
Beaudart, C; Bruyere, O; Dardenne, N; Emonts, P; Neuprez, A; Reginster, JY1
Reid, IR1
Briarava, M; Mocellin, S; Nitti, D; Pilati, P1
Allen, MR; Bivi, N; Burr, DB; Chalmers, MJ; Chavali, B; Dodge, JA; Durst, GL; Hu, H; Reutter, CT; Riley, A; Sato, M1
Burdette, JE; Davis, DA; Dean, M; Moyle-Heyrman, G; Schipma, MJ1
Fervers, F; Henrich, D; Kontradowitz, K; Leiblein, M; Marzi, I; Seebach, C1
Elgebaly, Z; Elliott, J; Naik-Panvelkar, P; Norman, S; Pollack, A; Seibel, MJ; Thistlethwaite, J; Weston, C1
Cherubini, K; de Figueiredo, MAZ; Koth, VS; Salum, FG1
Kosiorowska, J; Szymańska-Chabowska, A; Tański, W1
Hara, T; Hijikata, Y; Matsubara, Y; Watanabe, N1

Reviews

22 review(s) available for raloxifene hydrochloride and thiophenes

ArticleYear
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
    Breast cancer research and treatment, 1983, Volume: 3 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes

1983
Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer.
    Current opinion in obstetrics & gynecology, 2002, Volume: 14, Issue:1

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Endometrial Neoplasms; Female; Genes, Tumor Suppressor; Humans; Neoplasm Staging; Phosphoric Monoester Hydrolases; Piperidines; Progestins; PTEN Phosphohydrolase; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Survival Rate; Thiophenes; Tumor Suppressor Proteins

2002
Selective estrogen receptor modulators as a new therapeutic drug group: concept to reality in a decade.
    Clinical breast cancer, 2002, Volume: 2, Issue:4

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cinnamates; Drug Design; Forecasting; Humans; Molecular Biology; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Stilbenes; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Toremifene; Treatment Outcome

2002
A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer.
    Seminars in oncology, 2002, Volume: 29, Issue:3 Suppl 11

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes

2002
Selective estrogen receptor modulators: tissue actions and potential for CNS protection.
    CNS drug reviews, 2002,Fall, Volume: 8, Issue:3

    Topics: Animals; Breast Neoplasms; Cardiovascular System; Central Nervous System; Cognition; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Hormone Replacement Therapy; Humans; Hypothalamo-Hypophyseal System; Male; Neuroprotective Agents; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Receptors, Neurotransmitter; Structure-Activity Relationship; Tamoxifen; Thiophenes; Uterus

2002
Arzoxifene: a promising new selective estrogen receptor modulator for clinical chemoprevention of breast cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-15, Volume: 10, Issue:16

    Topics: Anticarcinogenic Agents; Breast Neoplasms; Female; Humans; Molecular Structure; Neoplasm Staging; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Thiophenes

2004
Breast cancer chemoprevention: a review of selective estrogen receptor modulators.
    Clinical journal of oncology nursing, 2005, Volume: 9, Issue:3

    Topics: Breast Neoplasms; Female; Humans; Piperidines; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes

2005
Osteoporosis prevention and therapy: preserving and building strength through bone quality.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2006, Volume: 17, Issue:12

    Topics: Bone and Bones; Bone Density; Bone Density Conservation Agents; Calcitonin; Diphosphonates; Estrogen Replacement Therapy; Female; Humans; Male; Organometallic Compounds; Osteoporosis; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes

2006
[Anabolic treatment for osteoporosis: PTH treatment].
    Clinical calcium, 2006, Volume: 16, Issue:9

    Topics: Anabolic Agents; Bone Density; Bone Density Conservation Agents; Diphosphonates; Drug Synergism; Drug Therapy, Combination; Fractures, Bone; Humans; Organometallic Compounds; Osteoporosis; Parathyroid Hormone; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Thiophenes

2006
[Drug treatment of postmenopausal osteoporosis. What's New in 2006].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:10 Pt 2

    Topics: Absorptiometry, Photon; Adult; Age Factors; Aged; Aged, 80 and over; Alendronate; Body Mass Index; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Female; Femoral Fractures; Follow-Up Studies; Fractures, Bone; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Practice Guidelines as Topic; Raloxifene Hydrochloride; Risk Factors; Spinal Fractures; Tablets; Teriparatide; Thiophenes; Time Factors

2006
Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls.
    Drugs, 2006, Volume: 66, Issue:16

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Neoplasms; Bone Remodeling; Bone Resorption; Calcitonin; Cathepsin K; Cathepsins; Collagen Type I; Denosumab; Diphosphonates; Drug Administration Schedule; Drug Design; Female; Humans; Organometallic Compounds; Osteitis Deformans; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Thiophenes

2006
Medicinal chemistry and emerging strategies applied to the development of selective estrogen receptor modulators (SERMs).
    Current medicinal chemistry, 2007, Volume: 14, Issue:11

    Topics: Breast Neoplasms; Drug Design; Estrogen Receptor alpha; Female; Humans; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stilbenes; Structure-Activity Relationship; Tamoxifen; Thiophenes; Toremifene

2007
[Current and future prospects for anti-osteoporotic drugs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 130, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Cholecalciferol; Clinical Trials as Topic; Denosumab; Diphosphonates; Drug Administration Schedule; Drug Design; Humans; Organometallic Compounds; Osteoporosis; Parathyroid Hormone; Patient Compliance; Raloxifene Hydrochloride; RANK Ligand; Selective Estrogen Receptor Modulators; Thiophenes

2007
Treatment of osteoporosis: all the questions we still cannot answer.
    The American journal of medicine, 2008, Volume: 121, Issue:9

    Topics: Age Factors; Bone Density; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; Fractures, Bone; Hormone Replacement Therapy; Humans; Organometallic Compounds; Osteoporosis; Raloxifene Hydrochloride; Teriparatide; Thiophenes; Time Factors

2008
Current and emerging pharmacologic therapies for the management of postmenopausal osteoporosis.
    Journal of women's health (2002), 2009, Volume: 18, Issue:10

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Denosumab; Drug Therapy, Combination; Female; Humans; Indoles; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Piperidines; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; RANK Ligand; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Vitamin D; Women's Health

2009
A comparison between bisphosphonates and other treatments for osteoporosis.
    Current pharmaceutical design, 2010, Volume: 16, Issue:27

    Topics: Bone Density Conservation Agents; Diphosphonates; Drug Costs; Drug Monitoring; Female; France; Humans; Male; Medication Adherence; Organometallic Compounds; Osteoporosis; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Teriparatide; Thiophenes

2010
Sustained vertebral antifracture efficacy of oral anti-osteoporotic therapies in postmenopausal osteoporosis.
    Current medical research and opinion, 2010, Volume: 26, Issue:11

    Topics: Aged; Bone Density Conservation Agents; Cervical Vertebrae; Diphosphonates; Female; Fractures, Bone; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Thiophenes; Treatment Outcome

2010
Preventive therapy for breast cancer: a consensus statement.
    The Lancet. Oncology, 2011, Volume: 12, Issue:5

    Topics: Anastrozole; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Consensus Development Conferences as Topic; Diphosphonates; Estrogen Receptor Modulators; Expert Testimony; Female; Fenretinide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Nitriles; Norpregnenes; Piperidines; Premenopause; Pyrrolidines; Raloxifene Hydrochloride; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Triazoles

2011
Efficacy and safety of currently marketed anti-osteoporosis medications.
    Best practice & research. Clinical endocrinology & metabolism, 2014, Volume: 28, Issue:6

    Topics: Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Denosumab; Diphosphonates; Humans; Indoles; Osteoporosis; Parathyroid Hormone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes

2014
Breast Cancer Chemoprevention: A Network Meta-Analysis of Randomized Controlled Trials.
    Journal of the National Cancer Institute, 2016, Volume: 108, Issue:2

    Topics: Adult; Aged; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Norpregnenes; Piperidines; Postmenopause; Primary Prevention; Pyrrolidines; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes

2016
Osteoporosis - risk factors, pharmaceutical and non-pharmaceutical treatment.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:9

    Topics: Cholecalciferol; Denosumab; Dietary Supplements; Diphosphonates; Exercise; Humans; Kinesiology, Applied; Osteoporosis; Raloxifene Hydrochloride; Risk Factors; Teriparatide; Thiophenes

2021
Pharmacological interventions versus placebo, no treatment or usual care for osteoporosis in people with chronic kidney disease stages 3-5D.
    The Cochrane database of systematic reviews, 2021, Jul-07, Volume: 7

    Topics: Antibodies, Monoclonal; Bias; Bone Density; Bone Density Conservation Agents; Denosumab; Female; Femur Neck; Fractures, Spontaneous; Hip; Humans; Indoles; Lumbar Vertebrae; Osteoporosis, Postmenopausal; Parathyroid Hormone-Related Protein; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Renal Dialysis; Renal Insufficiency, Chronic; Spinal Fractures; Teriparatide; Thiophenes; Watchful Waiting

2021

Trials

4 trial(s) available for raloxifene hydrochloride and thiophenes

ArticleYear
Effect of raloxifene on serum triglycerides in postmenopausal women: influence of predisposing factors for hypertriglyceridemia.
    Clinical therapeutics, 2001, Volume: 23, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Causality; Female; Humans; Hypertriglyceridemia; Middle Aged; Osteoporosis; Pancreatitis; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Triglycerides

2001
Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:7

    Topics: Aged; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Dose-Response Relationship, Drug; Double-Blind Method; Endometrium; Female; Humans; Lipids; Middle Aged; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Vasomotor System

2010
Arzoxifene versus raloxifene: effect on bone and safety parameters in postmenopausal women with osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2012, Volume: 23, Issue:3

    Topics: Absorptiometry, Photon; Aged; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Double-Blind Method; Female; Femur Neck; Hip Joint; Hot Flashes; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Thiophenes; Treatment Outcome

2012
Gynecologic effects of arzoxifene in postmenopausal women with osteoporosis or low bone mass.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Endometrial Neoplasms; Endometrium; Female; Genital Diseases, Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Piperidines; Placebos; Polyps; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Uterine Hemorrhage; Vaginitis; Vulvitis

2012

Other Studies

54 other study(ies) available for raloxifene hydrochloride and thiophenes

ArticleYear
The stimulation of uterine complement component C3 gene expression by antiestrogens.
    Endocrinology, 1990, Volume: 126, Issue:3

    Topics: Animals; Complement C3; Drug Interactions; Drug Synergism; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation; Kinetics; Nucleic Acid Hybridization; Piperidines; Progesterone; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; RNA, Messenger; Tamoxifen; Thiophenes; Uterus

1990
Non-steroidal antioestrogens--receptor binding and biological response in rat uterus, rat mammary carcinoma and human breast cancer cells.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Uterus

1984
Antioestrogenic and antitumour activities of a series of non-steroidal antioestrogens.
    The Journal of endocrinology, 1983, Volume: 99, Issue:3

    Topics: Animals; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Organ Size; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen; Thiophenes; Uterus

1983
Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL).
    Atherosclerosis, 1996, Sep-27, Volume: 126, Issue:1

    Topics: Animals; Antioxidants; Copper; Dexamethasone; Estradiol; Estrogen Antagonists; Free Radicals; Horseradish Peroxidase; Humans; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Peroxidase; Phagocytosis; Piperidines; Probucol; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Thiobarbituric Acid Reactive Substances; Thiophenes; Tyrosine

1996
LY353381.HCl: a novel raloxifene analog with improved SERM potency and efficacy in vivo.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Biomechanical Phenomena; Body Weight; Bone and Bones; Cholesterol; Estrogen Antagonists; Female; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Thiophenes; Uterus

1998
Raloxifene analog LY 117018 effects on central and peripheral beta-endorphin.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1999, Volume: 13, Issue:4

    Topics: Animals; beta-Endorphin; Estradiol; Estrogen Antagonists; Female; Hippocampus; Hypothalamus; Nervous System; Ovariectomy; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thiophenes

1999
17beta-estradiol, but not raloxifene, decreases thrombomodulin in the antithrombotic protein C pathway.
    Endocrinology, 2000, Volume: 141, Issue:10

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Estrogen Antagonists; Humans; Protein C; Pyrrolidines; Raloxifene Hydrochloride; Thiophenes; Thrombomodulin; Thrombosis; Umbilical Veins

2000
Effects of estradiol and raloxifene analog on brain, adrenal and serum allopregnanolone content in fertile and ovariectomized female rats.
    Neuroendocrinology, 2000, Volume: 72, Issue:3

    Topics: Adrenal Glands; Animals; Brain; Drug Combinations; Drug Interactions; Estradiol; Estrogen Antagonists; Female; Fertility; Hippocampus; Hypothalamus; Ovariectomy; Pituitary Gland; Pregnanolone; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thiophenes

2000
The oestrogen receptor and its selective modulators in gynaecological oncology.
    European journal of cancer (Oxford, England : 1990), 2000, Volume: 36 Suppl 4

    Topics: Antineoplastic Agents, Hormonal; Cinnamates; Estrogen Antagonists; Female; Genital Neoplasms, Female; Humans; Norpregnenes; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Stilbenes; Tamoxifen; Thiophenes; Toremifene

2000
Effects of raloxifene, a selective estrogen receptor modulator, on thymus, T cell reactivity, and inflammation in mice.
    Cellular immunology, 2000, Nov-01, Volume: 205, Issue:2

    Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Estradiol; Estrogen Antagonists; Female; Hypersensitivity, Delayed; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, SCID; Molecular Structure; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Thymus Gland

2000
Induction of endothelial nitric-oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Animals; Cell Line, Transformed; Cells, Cultured; CHO Cells; Cricetinae; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flavonoids; Fulvestrant; Humans; Lung; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estradiol; Thiophenes; Time Factors; Umbilical Veins

2001
Effects of oral estrogen, raloxifene and arzoxifene on gene expression in serotonin neurons of macaques.
    Psychoneuroendocrinology, 2002, Volume: 27, Issue:4

    Topics: Animals; Carrier Proteins; Estradiol; Estrogen Antagonists; Estrogen Replacement Therapy; Female; Gene Expression; Macaca mulatta; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Piperidines; Raloxifene Hydrochloride; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Estrogen Receptor Modulators; Serotonin Plasma Membrane Transport Proteins; Thiophenes; Tryptophan Hydroxylase

2002
Raloxifene analog LY117018 enhances the regeneration of sciatic nerve in ovariectomized female mice.
    Brain research, 2003, Aug-01, Volume: 980, Issue:1

    Topics: Animals; Estrogen Antagonists; Female; Histological Techniques; Mice; Mice, Inbred ICR; Nerve Regeneration; Ovariectomy; Pyrrolidines; Raloxifene Hydrochloride; Sciatic Nerve; Selective Estrogen Receptor Modulators; Thiophenes; Time Factors

2003
Effects of long-term administration of N-3 polyunsaturated fatty acids (PUFA) and selective estrogen receptor modulator (SERM) derivatives in ovariectomized (OVX) mice.
    Journal of cellular biochemistry, 2003, Oct-01, Volume: 90, Issue:2

    Topics: Adipose Tissue; Animals; Body Weight; Bone Marrow Cells; Cholesterol; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Fish Oils; Hypolipidemic Agents; Interleukin-1; Interleukin-10; Interleukin-6; Mice; Mice, Inbred BALB C; Ovariectomy; Ovary; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Skin; Spleen; Thiophenes; Triglycerides; Tumor Necrosis Factor-alpha

2003
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens.
    Journal of molecular endocrinology, 2004, Volume: 32, Issue:2

    Topics: Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Fulvestrant; Genes, Reporter; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Pyrrolidines; Raloxifene Hydrochloride; Response Elements; Tamoxifen; Thiophenes; Transcription, Genetic; Tumor Cells, Cultured

2004
Effects of the selective estrogen receptor modulator LY117018 on growth hormone secretion: In vitro studies.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:5

    Topics: Adenoma; Adult; Aged; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Middle Aged; Pituitary Gland; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Secretory Rate; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes

2004
Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor alpha and their bioactivities in vivo.
    Bioorganic & medicinal chemistry letters, 2005, Mar-01, Volume: 15, Issue:5

    Topics: Animals; Binding, Competitive; Bone Density; Drug Evaluation, Preclinical; Estrogen Receptor alpha; Female; Ligands; Mice; Molecular Structure; Piperazines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Thiophenes; Uterus

2005
Efficient access to 2-aryl-3-substituted benzo[b]thiophenes.
    The Journal of organic chemistry, 2005, Apr-29, Volume: 70, Issue:9

    Topics: Cyclization; Molecular Structure; Oxidation-Reduction; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Thiophenes

2005
Anti-growth factor activities of benzothiophenes in human breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 94, Issue:5

    Topics: Breast Neoplasms; Cell Proliferation; Estrogen Antagonists; Humans; Insulin-Like Growth Factor I; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes; Transcription Factor AP-1; Transcription, Genetic

2005
Activity of estradiol and selective estrogen receptor modulators in the mouse N20.1 oligodendrocyte/astrocytes cell line.
    Neuro endocrinology letters, 2005, Volume: 26, Issue:5

    Topics: Animals; Astrocytes; Blotting, Western; Cell Line; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation; Ligands; Luciferases; Mice; Neuroglia; Oligodendroglia; Plasmids; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Transfection

2005
AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines.
    BMC cancer, 2006, May-02, Volume: 6

    Topics: Acetyltransferases; Alleles; Breast Neoplasms; Cell Line, Tumor; Cloning, Molecular; Drug Resistance, Neoplasm; Estradiol; Fulvestrant; Histone Acetyltransferases; Humans; Nuclear Receptor Coactivator 3; Oncogene Proteins; Peptides; Polymerase Chain Reaction; Pyrrolidines; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Selective Estrogen Receptor Modulators; Sequence Analysis, DNA; Tamoxifen; Thiophenes; Trans-Activators

2006
Boning up on osteoporosis--current thinking on management. Interview by Emma Buchanan.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2006, Volume: 96, Issue:7

    Topics: Accidental Falls; Age Factors; Bone Density Conservation Agents; Diphosphonates; Humans; Organometallic Compounds; Osteoarthritis; Raloxifene Hydrochloride; Teriparatide; Thiophenes

2006
[Osteoporosis priority: Reduce the number of fractures].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:10 Pt 2

    Topics: Absorptiometry, Photon; Age Factors; Aged; Bone Density; Bone Density Conservation Agents; Diphosphonates; Female; Femoral Fractures; Fractures, Bone; Humans; Male; Middle Aged; Organometallic Compounds; Osteoporosis; Osteoporosis, Postmenopausal; Prospective Studies; Raloxifene Hydrochloride; Risk Factors; Spinal Fractures; Teriparatide; Thiophenes; Time Factors

2006
An analysis of which anti-osteoporosis therapeutic regimen would improve compliance in a population of elderly adults.
    Current medical research and opinion, 2007, Volume: 23, Issue:2

    Topics: Aged; Cohort Studies; Diphosphonates; Drug Administration Schedule; Fasting; Female; Humans; Male; Middle Aged; Organometallic Compounds; Osteoporosis; Patient Compliance; Patient Satisfaction; Posture; Raloxifene Hydrochloride; Registries; Single-Blind Method; Surveys and Questionnaires; Teriparatide; Thiophenes; Twins

2007
Uterine peroxidase-catalyzed formation of diquinone methides from the selective estrogen receptor modulators raloxifene and desmethylated arzoxifene.
    Chemical research in toxicology, 2007, Volume: 20, Issue:11

    Topics: Alkylation; Animals; Catalysis; Female; Glutathione; Horseradish Peroxidase; Indolequinones; Microsomes; Piperidines; Quinones; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators; Thiophenes; Uterus

2007
Pharmacophore mapping of arylbenzothiophene derivatives for MCF cell inhibition using classical and 3D space modeling approaches.
    Journal of molecular graphics & modelling, 2008, Volume: 26, Issue:5

    Topics: Animals; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Molecular; Piperidines; Quantitative Structure-Activity Relationship; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Thiophenes

2008
Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene.
    ChemMedChem, 2007, Volume: 2, Issue:10

    Topics: Animals; Female; Lipids; Organ Size; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Thiophenes; Uterus

2007
Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:9

    Topics: Animals; Antioxidants; Breast Neoplasms; Carcinoma, Hepatocellular; Chemoprevention; Female; Humans; Liver; Liver Neoplasms; Luciferases; Mice; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Peroxides; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Thiophenes; Tumor Cells, Cultured

2007
Osteoporosis: non-hormonal treatment.
    Climacteric : the journal of the International Menopause Society, 2007, Volume: 10 Suppl 2

    Topics: Alendronate; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Calcitonin; Calcium, Dietary; Denosumab; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Female; Fractures, Bone; Humans; Ibandronic Acid; Organometallic Compounds; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; RANK Ligand; Risedronic Acid; Thiophenes; Vitamin D; Women's Health

2007
Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and osteoporosis.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:10

    Topics: Animals; Arthritis; Arthritis, Experimental; Bone Density; Cytokines; Female; Humans; Mice; Osteoporosis, Postmenopausal; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Thiophenes; Treatment Outcome; Tumor Necrosis Factor-alpha

2007
Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidants; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Thiophenes

2008
Comparative methods for analysis of protein covalent modification by electrophilic quinoids formed from xenobiotics.
    Bioconjugate chemistry, 2009, Volume: 20, Issue:4

    Topics: Animals; Azides; Biotinylation; Cell Extracts; Cell Line, Tumor; Hepatocytes; Indicators and Reagents; Ligands; Mass Spectrometry; Oxidation-Reduction; Piperidines; Proteins; Quinones; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Staining and Labeling; Thiophenes; Xenobiotics

2009
In vivo activation of gene transcription via oestrogen response elements by a raloxifene analogue.
    The Journal of endocrinology, 2009, Volume: 203, Issue:3

    Topics: Animals; Bone Density; Estradiol; Estrogen Antagonists; Estrogens; Female; Femur; Luciferases; Mice; Mice, Inbred CBA; Mice, Transgenic; Organ Size; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Response Elements; Thiophenes; Thymus Gland; Transcription, Genetic; Uterus

2009
Effects of strontium ranelate, raloxifene and misoprostol on bone mineral density in ovariectomized rats.
    European journal of obstetrics, gynecology, and reproductive biology, 2009, Volume: 147, Issue:2

    Topics: Animals; Bone Density; Bone Density Conservation Agents; Female; Humans; Misoprostol; Organometallic Compounds; Osteoporosis, Postmenopausal; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Thiophenes

2009
Use of bisphosphonates and raloxifene and risk of deep venous thromboembolism and pulmonary embolism.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:9

    Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Denmark; Diphosphonates; Dose-Response Relationship, Drug; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Organometallic Compounds; Osteoporosis; Pulmonary Embolism; Raloxifene Hydrochloride; Thiophenes; Venous Thromboembolism

2010
Effect of selective estrogen receptor modulator/raloxifene analogue on proliferation and collagen metabolism of tendon fibroblast.
    Connective tissue research, 2010, Volume: 51, Issue:3

    Topics: Achilles Tendon; Animals; Bromodeoxyuridine; Cell Proliferation; Cell Survival; Cells, Cultured; Collagen Type I; Collagen Type III; Elastin; Estradiol; Estrogen Antagonists; Extracellular Matrix; Female; Fibroblasts; Fulvestrant; Matrix Metalloproteinase 13; Pyrrolidines; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators; Tetrazolium Salts; Thiophenes

2010
Risk of femoral shaft and subtrochanteric fractures among users of bisphosphonates and raloxifene.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011, Volume: 22, Issue:3

    Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Case-Control Studies; Denmark; Diphosphonates; Female; Femoral Fractures; Hip Fractures; Humans; Male; Middle Aged; Organometallic Compounds; Osteoporosis; Raloxifene Hydrochloride; Risk Factors; Thiophenes

2011
Gastrointestinal tolerability and patterns of switching in patients treated for primary osteoporosis: the Swedish Adherence Register Analysis (SARA).
    Calcified tissue international, 2011, Volume: 89, Issue:3

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Etidronic Acid; Female; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Male; Medication Adherence; Middle Aged; Organometallic Compounds; Osteoporosis; Raloxifene Hydrochloride; Registries; Retrospective Studies; Risedronic Acid; Sweden; Thiophenes

2011
Oral bisphosphonate use increases the risk for inflammatory jaw disease: a cohort study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2012, Volume: 70, Issue:4

    Topics: Administration, Oral; Aged; Alcoholism; Alendronate; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Case-Control Studies; Cohort Studies; Denmark; Diabetes Complications; Diphosphonates; Drug Therapy; Etidronic Acid; Female; Humans; Jaw Diseases; Male; Neoplasms; Organometallic Compounds; Osteitis; Osteomyelitis; Osteoporosis; Parathyroid Hormone; Periostitis; Radiotherapy; Raloxifene Hydrochloride; Risk Factors; Sjogren's Syndrome; Strontium; Thiophenes

2012
Persistence with osteoporosis medications among postmenopausal women in the UK General Practice Research Database.
    Menopause (New York, N.Y.), 2012, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Alendronate; Bone Density Conservation Agents; Databases, Factual; Diphosphonates; Female; General Practice; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Patient Compliance; Postmenopause; Raloxifene Hydrochloride; Thiophenes; Time Factors; United Kingdom

2012
Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Breast; Catechols; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Deoxyguanosine; DNA Adducts; Enzyme Induction; Epithelial Cells; Estrogens; Female; Histone Deacetylase Inhibitors; Horses; Humans; Oxidation-Reduction; Oxidative Stress; Piperidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Thiophenes

2011
MENOPOST--calcium and vitamin D supplementation in postmenopausal osteoporosis treatment: a descriptive cohort study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:2

    Topics: Administration, Oral; Age Distribution; Aged; Aged, 80 and over; Bone Density; Bone Density Conservation Agents; Calcium; Dietary Supplements; Diphosphonates; Drug Administration Schedule; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Female; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Retrospective Studies; Thiophenes; Treatment Outcome; Vitamin D

2013
Preventive therapy for breast cancer.
    Current oncology reports, 2012, Volume: 14, Issue:6

    Topics: Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrial Neoplasms; Female; Humans; Meta-Analysis as Topic; Middle Aged; Piperidines; Preventive Medicine; Pyrrolidines; Raloxifene Hydrochloride; Receptor, ErbB-2; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes

2012
Treatment of osteoporosis and hip fractures in a Spanish health area.
    European review for medical and pharmacological sciences, 2013, Volume: 17, Issue:2

    Topics: Bone Density Conservation Agents; Diphosphonates; Hip Fractures; Humans; Longitudinal Studies; Organometallic Compounds; Osteoporosis; Raloxifene Hydrochloride; Retrospective Studies; Spain; Thiophenes

2013
[Postmenopausal osteoporosis: Primary prevention or excessive use of medications].
    Semergen, 2013, Volume: 39, Issue:3

    Topics: Aged; Cross-Sectional Studies; Diphosphonates; Drug Utilization; Female; Humans; Middle Aged; Organometallic Compounds; Osteoporosis, Postmenopausal; Primary Prevention; Raloxifene Hydrochloride; Thiophenes

2013
[As regards "Post-menopausal osteoporosis: primary prevention or excessive medication"].
    Semergen, 2014, Volume: 40, Issue:2

    Topics: Diphosphonates; Drug Utilization; Female; Humans; Organometallic Compounds; Osteoporosis, Postmenopausal; Primary Prevention; Raloxifene Hydrochloride; Thiophenes

2014
SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites.
    Cancer prevention research (Philadelphia, Pa.), 2014, Volume: 7, Issue:5

    Topics: Cell Transformation, Neoplastic; Cells, Cultured; Cytoprotection; Estradiol; Humans; Inactivation, Metabolic; Indoles; Mammary Glands, Human; MCF-7 Cells; Oxidants; Oxidative Stress; Piperidines; Raloxifene Hydrochloride; Reactive Oxygen Species; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Up-Regulation

2014
Evaluation of the prescription of osteoporosis treatment after a major osteoporotic fracture.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2014, Volume: 20, Issue:6

    Topics: Aged; Aged, 80 and over; Bone Density Conservation Agents; Calcium; Dietary Supplements; Diphosphonates; Female; Follow-Up Studies; Fractures, Bone; France; Hip Fractures; Humans; Imidazoles; Male; Middle Aged; Osteoporosis; Osteoporotic Fractures; Prescriptions; Raloxifene Hydrochloride; Retrospective Studies; Thiophenes; Treatment Outcome; Vitamin D; Wrist Injuries; Zoledronic Acid

2014
Efficacy, effectiveness and side effects of medications used to prevent fractures.
    Journal of internal medicine, 2015, Volume: 277, Issue:6

    Topics: Alendronate; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Calcium Compounds; Denosumab; Diphosphonates; Etidronic Acid; Evidence-Based Medicine; Hip Fractures; Humans; Ibandronic Acid; Imidazoles; Osteoporosis; Osteoporotic Fractures; Raloxifene Hydrochloride; Risedronic Acid; Risk Assessment; Spinal Fractures; Teriparatide; Thiophenes; Treatment Outcome; Vitamin D; Zoledronic Acid

2015
Structural features underlying raloxifene's biophysical interaction with bone matrix.
    Bioorganic & medicinal chemistry, 2016, 02-15, Volume: 24, Issue:4

    Topics: Animals; Bone Matrix; Collagen; Dogs; Durapatite; Femur; Hydrophobic and Hydrophilic Interactions; Male; Piperidines; Polylysine; Protein Binding; Raloxifene Hydrochloride; Receptors, Estrogen; Static Electricity; Structure-Activity Relationship; Thiophenes

2016
Genome-wide transcriptional regulation of estrogen receptor targets in fallopian tube cells and the role of selective estrogen receptor modulators.
    Journal of ovarian research, 2016, Feb-15, Volume: 9

    Topics: Animals; Antineoplastic Agents, Hormonal; Carcinoma in Situ; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogen Antagonists; Estrogens; Fallopian Tubes; Female; Gene Expression Regulation, Neoplastic; Genome; Humans; Mice; Neoplasms, Cystic, Mucinous, and Serous; Ovarian Neoplasms; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Thiophenes; Transcriptome

2016
Do antiosteoporotic drugs improve bone regeneration in vivo?
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2020, Volume: 46, Issue:2

    Topics: Absorptiometry, Photon; Alendronate; Alkaline Phosphatase; Animals; Biomechanical Phenomena; Blotting, Western; Bone Density; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Bone Regeneration; Bony Callus; Calcium-Regulating Hormones and Agents; Collagen Type I; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-6; Macrophage Colony-Stimulating Factor; Osteocalcin; Osteogenesis; Osteogenesis, Distraction; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Rats; Reverse Transcriptase Polymerase Chain Reaction; Simvastatin; Thiophenes; Tomography, X-Ray Computed

2020
Osteoporosis management in Australian general practice: an analysis of current osteoporosis treatment patterns and gaps in practice.
    BMC family practice, 2020, 02-12, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Attitude of Health Personnel; Australia; Bone Density Conservation Agents; Denosumab; Deprescriptions; Diphosphonates; Drug Substitution; Female; General Practice; General Practitioners; Humans; Longitudinal Studies; Male; Middle Aged; Norpregnenes; Osteoporosis; Osteoporotic Fractures; Practice Patterns, Physicians'; Raloxifene Hydrochloride; Retrospective Studies; Teriparatide; Thiophenes

2020
Morphological and immunohistochemical features of tooth extraction sites in rats treated with alendronate, raloxifene, or strontium ranelate.
    Clinical oral investigations, 2021, Volume: 25, Issue:5

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Humans; Raloxifene Hydrochloride; Rats; Rats, Wistar; Thiophenes; Tooth Extraction

2021