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raloxifene hydrochloride and ospemifene

raloxifene hydrochloride has been researched along with ospemifene in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (58.82)29.6817
2010's7 (41.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cockcroft, N; Dahllund, J; Härkönen, P; Hemminki, K; Kangas, L; Koskinen, M; Laine, A; Peng, Z; Qu, Q; Väänänen, K; Zheng, H1
Härkönen, PL; Kangas, L; Zheng, H1
Häyry, P; Kangas, L; Luoto, NM; Savolainen-Peltonen, H1
DeGregorio, MW; Erkkola, R; Härkönen, P; Kivinen, S; Komi, J; Lankinen, KS; Tuimala, R; Vihko, K; Vihtamäki, T; Voipio, S; Ylikorkala, O1
Beckett, LA; Degregorio, MW; Gregg, JP; Marchisano-Karpman, C; Read, KC; Wurz, GT; Yu, Q1
DeGregorio, M; Erkkola, R; Halonen, K; Heikkinen, J; Komi, J; Lammintausta, R; Lankinen, KS; Saarikoski, S; Tuppurainen, M; Väänänen, K; Ylikorkala, O1
Botsis, DC; Christodoulakos, GE; Lambrinoudaki, IV1
Härkönen, PL; Hentunen, TA; Kangas, L; Michael, H; Väänänen, HK1
Guo, T; Härkönen, P; Kallio, A; Kangas, L; Lamminen, E; Seppänen, J; Väänänen, HK1
Lewiecki, EM1
Biserni, A; Caruso, D; Ciana, P; Horner, D; Komm, B; Maggi, A; Ramachandran, B; Rando, G1
Kari, S; Lammintausta, R; Unkila, M; Yatkin, E1
Pinkerton, JV; Stanczyk, FZ1
Pinkerton, JV; Thomas, S1
Komm, BS; Pickar, JH1
Eigeliene, N; Erkkola, R; Härkönen, P1
Eigeliene, N; Erkkola, R; Härkönen, P; Hellmer, C; Kangas, L; Kauko, T1

Reviews

5 review(s) available for raloxifene hydrochloride and ospemifene

ArticleYear
The cardiovascular effects of selective estrogen receptor modulators.
    Annals of the New York Academy of Sciences, 2006, Volume: 1092

    Topics: Cardiovascular System; Estradiol; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Toremifene

2006
Current and emerging pharmacologic therapies for the management of postmenopausal osteoporosis.
    Journal of women's health (2002), 2009, Volume: 18, Issue:10

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bone Density Conservation Agents; Denosumab; Drug Therapy, Combination; Female; Humans; Indoles; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Piperidines; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; RANK Ligand; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Vitamin D; Women's Health

2009
Clinical effects of selective estrogen receptor modulators on vulvar and vaginal atrophy.
    Menopause (New York, N.Y.), 2014, Volume: 21, Issue:3

    Topics: Atrophy; Estrogens; Estrogens, Conjugated (USP); Female; Humans; Indoles; Pelvic Organ Prolapse; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Treatment Outcome; Vagina; Vaginal Diseases; Vulva; Vulvar Diseases

2014
Use of SERMs for treatment in postmenopausal women.
    The Journal of steroid biochemistry and molecular biology, 2014, Volume: 142

    Topics: Breast Neoplasms; Clinical Trials as Topic; Dyspareunia; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Indoles; Osteoporosis; Osteoporosis, Postmenopausal; Postmenopause; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Toremifene

2014
Selective estrogen receptor modulators and the combination therapy conjugated estrogens/bazedoxifene: A review of effects on the breast.
    Post reproductive health, 2015, Volume: 21, Issue:3

    Topics: Animals; Breast; Breast Neoplasms; Drug Therapy, Combination; Estradiol; Estrogen Antagonists; Estrogens; Estrogens, Conjugated (USP); Female; Fulvestrant; Humans; Indoles; Osteoporosis; Postmenopause; Protective Factors; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen; Toremifene

2015

Trials

3 trial(s) available for raloxifene hydrochloride and ospemifene

ArticleYear
Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women.
    Menopause (New York, N.Y.), 2005, Volume: 12, Issue:2

    Topics: Double-Blind Method; Drug Administration Schedule; Female; Follicle Stimulating Hormone; Hot Flashes; Humans; Lipids; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Sex Hormone-Binding Globulin; Tamoxifen; Treatment Outcome; Uterus; Vagina

2005
Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women.
    Journal of bone and mineral metabolism, 2006, Volume: 24, Issue:4

    Topics: Biomarkers; Bone Remodeling; Collagen; Double-Blind Method; Female; Finland; Humans; Osteoporosis, Postmenopausal; Postmenopause; Raloxifene Hydrochloride; Tamoxifen

2006
Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause.
    The Journal of steroid biochemistry and molecular biology, 2013, Volume: 138

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Ethinyl Estradiol; Female; Humans; Menopause; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tamoxifen; Vagina; Vaginal Diseases; Vulva

2013

Other Studies

9 other study(ies) available for raloxifene hydrochloride and ospemifene

ArticleYear
Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats.
    Endocrinology, 2000, Volume: 141, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone and Bones; Breast Neoplasms; Cholesterol; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organ Size; Osteoporosis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Toremifene; Transplantation, Heterologous; Tumor Cells, Cultured; Uterus

2000
Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus.
    The Journal of steroid biochemistry and molecular biology, 2004, Volume: 88, Issue:2

    Topics: Animals; Base Sequence; DNA Primers; DNA Replication; Estrogen Receptor Modulators; Female; Gene Expression Regulation; Genes, fos; Organ Size; Polymerase Chain Reaction; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tamoxifen; Uterus; Vascular Endothelial Growth Factor A

2004
Selective estrogen receptor modulators prevent neointima formation after vascular injury.
    Molecular and cellular endocrinology, 2004, Nov-30, Volume: 227, Issue:1-2

    Topics: Animals; Aorta; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Estradiol; Estrogens; Female; Fulvestrant; Muscle, Smooth, Vascular; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators; Tamoxifen; Tunica Intima

2004
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 97, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen

2005
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro.
    British journal of pharmacology, 2007, Volume: 151, Issue:3

    Topics: Animals; Apoptosis; Bone Resorption; Cattle; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Lipopolysaccharide Receptors; Macrophage Colony-Stimulating Factor; Monocytes; Osteoclasts; Osteoprotegerin; Raloxifene Hydrochloride; RANK Ligand; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Tumor Necrosis Factor-alpha

2007
Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells.
    Molecular and cellular endocrinology, 2008, Jul-16, Volume: 289, Issue:1-2

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Etoposide; Humans; Interleukin-6; Osteoblasts; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen

2008
An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:4

    Topics: Animals; Blotting, Western; Estradiol; Estrogens, Conjugated (USP); Female; Indoles; Mice; Mice, Inbred C57BL; Ovariectomy; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Transcription, Genetic

2010
Comparison of the Effects of the Selective Estrogen Receptor Modulators Ospemifene, Raloxifene, and Tamoxifen on Breast Tissue in Ex Vivo Culture.
    Methods in molecular biology (Clifton, N.J.), 2016, Volume: 1366

    Topics: Apoptosis; Biomarkers; Breast; Cell Proliferation; Estradiol; Estrogen Receptor alpha; Female; Humans; Immunohistochemistry; Paraffin Embedding; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Tissue Culture Techniques; Tissue Fixation

2016
Effects of ospemifene, a novel selective estrogen-receptor modulator, on human breast tissue ex vivo.
    Menopause (New York, N.Y.), 2016, Volume: 23, Issue:7

    Topics: Aged; Apolipoproteins D; Apoptosis; Breast; Cell Proliferation; Estrogen Receptor alpha; Female; Humans; Middle Aged; Polymorphism, Genetic; Postmenopause; Raloxifene Hydrochloride; Receptors, Androgen; Selective Estrogen Receptor Modulators; Tamoxifen; Trefoil Factor-1

2016