raloxifene hydrochloride has been researched along with cysteine in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baer, BR; Rock, DA; Wienkers, LC | 1 |
| Dickmann, LJ; Foti, RS; Halpert, JR; Kumar, S; Pearson, JT; Rock, DA; Wahlstrom, JL; Wienkers, LC | 1 |
| Davis, JA; Foti, RS; Pearson, JT; Rock, DA; VandenBrink, BM; Wienkers, LC | 1 |
3 other study(ies) available for raloxifene hydrochloride and cysteine
| Article | Year |
|---|---|
Time-dependent inactivation of P450 3A4 by raloxifene: identification of Cys239 as the site of apoprotein alkylation.
Topics: Alkylating Agents; Alkylation; Apoproteins; Binding Sites; Cysteine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endopeptidase K; Enzyme Inhibitors; Estrogen Antagonists; Glutathione; Iodoacetamide; Kinetics; Midazolam; Molecular Structure; Quinolines; Raloxifene Hydrochloride; Recombinant Proteins; Sequence Analysis, Protein; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Time Factors | 2007 |
Differential time-dependent inactivation of P450 3A4 and P450 3A5 by raloxifene: a key role for C239 in quenching reactive intermediates.
Topics: Cloning, Molecular; Cysteine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Escherichia coli; Humans; Models, Molecular; Mutation; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Time Factors | 2007 |
Cytochrome p450 architecture and cysteine nucleophile placement impact raloxifene-mediated mechanism-based inactivation.
Topics: Catalytic Domain; Computer Simulation; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Kinetics; Models, Molecular; Raloxifene Hydrochloride | 2012 |