Page last updated: 2024-08-23

raloxifene hydrochloride and allopurinol

raloxifene hydrochloride has been researched along with allopurinol in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (33.33)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Obach, RS	1
Choe, J; Han, S; Jeon, WK; Kim, BC; Kim, EY; Lee, SA; Woo, CH	1
Bates, BS; Blobaum, AL; Brewer, KA; Bridges, TM; Byers, FW; Conn, PJ; Corlew, MM; Daniels, JS; Emmitte, KA; Felts, AS; Jones, CK; Lindsley, CW; Manka, J; Morrison, RD; Niswender, CM; Rodriguez, AL; Rush, R; Sanchez-Ponce, R; Santomango, TS; Stec, D; Venable, DF	1
Cantu-Medellin, N; Choughule, KV; Jones, JP; Kelley, EE; Schoenborn, SO; Weidert, ER	1
Adusumalli, S; Akhlaghi, F; Jamwal, R; Leggio, L; Obach, RS; Ryder, TF	1

Trials

1 trial(s) available for raloxifene hydrochloride and allopurinol

Article	Year
Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach. Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:8 Topics: Administration, Oral; Alcoholism; Aldehyde Oxidase; Animals; Azetidines; Biotransformation; Cytosol; Febuxostat; Female; Ghrelin; Hepatocytes; Humans; Liver; Mice; Microsomes, Liver; Molybdenum; Raloxifene Hydrochloride; Receptors, Ghrelin; Spiro Compounds; Xanthine Oxidase	2019

Article

Year

Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.

Drug metabolism and disposition: the biological fate of chemicals, 2019, Volume: 47, Issue:8

Topics: Administration, Oral; Alcoholism; Aldehyde Oxidase; Animals; Azetidines; Biotransformation; Cytosol; Febuxostat; Female; Ghrelin; Hepatocytes; Humans; Liver; Mice; Microsomes, Liver; Molybdenum; Raloxifene Hydrochloride; Receptors, Ghrelin; Spiro Compounds; Xanthine Oxidase

2019

Other Studies

5 other study(ies) available for raloxifene hydrochloride and allopurinol

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Potent inhibition of human liver aldehyde oxidase by raloxifene. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:1 Topics: Aldehyde Oxidase; Benzaldehydes; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Liver; Nicotine; Oxidation-Reduction; Phthalazines; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Xanthine Oxidase	2004
The inhibitory effect of raloxifene on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells is mediated through a ROS/p38 MAPK/CREB pathway to the up-regulation of heme oxygenase-1 independent of estrogen receptor. Biochimie, 2011, Volume: 93, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cyclic AMP Response Element-Binding Protein; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Hydrogen Peroxide; Iron; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Raloxifene Hydrochloride; Reactive Oxygen Species; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Signal Transduction; Up-Regulation; Xanthine; Xanthine Oxidase	2011
The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:9 Topics: Aldehyde Oxidase; Allopurinol; Animals; Benzamides; Biotransformation; Chromatography, Liquid; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hepatocytes; Humans; Hydroxylation; Injections, Intravenous; Liver; Macaca fascicularis; Magnetic Resonance Spectroscopy; Male; Metabolic Clearance Rate; Microsomes, Liver; Models, Biological; Molecular Structure; Oxygen Isotopes; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Species Specificity; Tandem Mass Spectrometry; Thiazoles; Xanthine Oxidase	2012
Inhibition of xanthine oxidase by the aldehyde oxidase inhibitor raloxifene: implications for identifying molybdopterin nitrite reductases. Nitric oxide : biology and chemistry, 2014, Feb-15, Volume: 37 Topics: Aldehyde Oxidase; Coenzymes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Metalloproteins; Molybdenum Cofactors; Nitric Oxide; Nitrite Reductases; Pteridines; Raloxifene Hydrochloride; Structure-Activity Relationship; Xanthine Oxidase	2014