Compounds > raloxifene
Page last updated: 2024-08-16

raloxifene and bazedoxifene

raloxifene has been researched along with bazedoxifene in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Abou-Gharbia, MA; Bender, RH; Collini, MD; Greenberger, LM; Harris, HA; Henderson, RA; Kharode, YP; Komm, BS; Lyttle, CR; Marzolf, JT; Miller, CP; Moran, RA; Tran, BD; Unwalla, RJ; Yardley, JP1
Birzin, ET; Blizzard, TA; Chan, W; DaSilva, CA; Dininno, F; Hammond, ML; Hayes, EC; Morgan, JD; Mosley, RT; Pai, LY; Rohrer, SP; Yang, YT1
Furukawa, T; Hosoya, K; Kadono, K; Moriguchi, H; Nakamori, F; Naritomi, Y; Teramura, T; Terashita, S; Tetsuka, K; Yamano, K1
Jou, D; Kumari, V; Li, C; Li, H; Lin, J; Lin, L; Xiao, H1
Balogh, I; Kim, HY; Koczok, K; Korade, Z; Liu, W; Mirnics, K; Porter, NA; Tallman, KA; Xu, L1
Chen, H; Dubrovyskyii, O; Dye, K; Gordon-Blake, J; Gutgesell, LM; He, D; Hollas, M; Huang, F; Lasek, AW; Lee, S; Li, Y; Lu, Y; Rosales, CI; Shen, Z; Thatcher, GRJ; Tonetti, DA; Wang, Y; Xiong, R; Zhao, H; Zhao, J1
Anantpadma, M; Cheng, H; Cooper, L; Davey, RA; Dye, K; Li, Y; Medegan Fagla, B; Nowar, R; Rong, L; Schafer, A; Shen, Z; Thatcher, GRJ; Xiong, R1

Other Studies

7 other study(ies) available for raloxifene and bazedoxifene

ArticleYear
Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.
    Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11

    Topics: Animals; Bone Density; Cell Line; Estradiol Congeners; Female; Indoles; Models, Molecular; Organ Size; Ovariectomy; Radioligand Assay; Rats; Structure-Activity Relationship; Transfection; Uterus

2001
Estrogen receptor ligands. Part 14: application of novel antagonist side chains to existing platforms.
    Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

    Topics: Animals; Estrogen Receptor alpha; Ligands; Oxathiins; Rats; Selective Estrogen Receptor Modulators

2005
Quantitative prediction of human intestinal glucuronidation effects on intestinal availability of UDP-glucuronosyltransferase substrates using in vitro data.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:9

    Topics: Administration, Oral; Biotransformation; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Glucuronides; Glucuronosyltransferase; Humans; Intestinal Absorption; Intestines; Isoenzymes; Kinetics; Metabolic Clearance Rate; Microsomes; Models, Biological; Pharmaceutical Preparations; Recombinant Proteins; Substrate Specificity

2012
Drug design targeting protein-protein interactions (PPIs) using multiple ligand simultaneous docking (MLSD) and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface.
    Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytokine Receptor gp130; Drug Design; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Indoles; Interleukin-6; Ligands; Molecular Docking Simulation; Phosphorylation; Protein Interaction Domains and Motifs; Protein Multimerization; Raloxifene Hydrochloride; Signal Transduction; STAT3 Transcription Factor

2014
The Effect of Small Molecules on Sterol Homeostasis: Measuring 7-Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts.
    Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3

    Topics: Animals; Cell Line; Dehydrocholesterols; Dose-Response Relationship, Drug; Fibroblasts; Homeostasis; Humans; Mice; Molecular Conformation; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Small Molecule Libraries; Sterols; Structure-Activity Relationship

2016
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
    Journal of medicinal chemistry, 2019, 12-26, Volume: 62, Issue:24

    Topics: Animals; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Mutation; Proteolysis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Thiophenes; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Screening and Reverse-Engineering of Estrogen Receptor Ligands as Potent Pan-Filovirus Inhibitors.
    Journal of medicinal chemistry, 2020, 10-08, Volume: 63, Issue:19

    Topics: Antiviral Agents; Cell Line, Tumor; Drug Evaluation, Preclinical; Filoviridae; Humans; Ligands; Membrane Fusion; Models, Biological; Receptors, Estrogen; Structure-Activity Relationship

2020