Page last updated: 2024-08-16

raloxifene and afimoxifene

raloxifene has been researched along with afimoxifene in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Bischoff, SF; Buhl, T; Floersheim, P; Fournier, B; Halleux, C; Kallen, J; Keller, H; Renaud, J; Schlaeppi, JM; Stark, W1
Akhtar Siddiqui, J; Akhtar, T; Chakravarti, B; Chattopadhyay, N; Datta, D; Dhar Dwivedi, SK; Godbole, MM; Khan, K; Konwar, R; Kumar, A; Kumar, H; Lal, J; Mishra, DP; Pal, S; Rai, B; Rath, SK; Sanyal, S; Singh, AK; Thakur, R; Trivedi, AK; Yadav, M1
Brown, HA; Brown, KA; Cho, CH; Jung, DI; Larock, RC; Lavieri, RR; Lindsley, CW; O'Reilly, MC; Scott, SA; Spencer, CT1
Hashimoto, Y; Makishima, M; Nanjyo, S; Noguchi-Yachide, T; Ohgane, K; Yoshioka, H1
Chen, H; Dubrovyskyii, O; Dye, K; Gordon-Blake, J; Gutgesell, LM; He, D; Hollas, M; Huang, F; Lasek, AW; Lee, S; Li, Y; Lu, Y; Rosales, CI; Shen, Z; Thatcher, GRJ; Tonetti, DA; Wang, Y; Xiong, R; Zhao, H; Zhao, J1
Carlsson, B; Enmark, E; Grandien, K; Gustafsson, JA; Häggblad, J; Kuiper, GG; Nilsson, S1
Bai, C; Luo, G; Ren, S; Wu, S; Xiang, H; Zhu, M2

Other Studies

8 other study(ies) available for raloxifene and afimoxifene

ArticleYear
Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands.
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Administration, Oral; Animals; Binding Sites; Biological Availability; Cell Division; Crystallography, X-Ray; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; HeLa Cells; Humans; Isoquinolines; Ligands; Models, Molecular; Radioligand Assay; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Transcription, Genetic; Tumor Cells, Cultured

2003
Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents.
    Journal of medicinal chemistry, 2014, Oct-09, Volume: 57, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzhydryl Compounds; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; ErbB Receptors; Humans; Mice; Neoplasm Invasiveness; Neoplastic Stem Cells; Oximes; Signal Transduction; Structure-Activity Relationship

2014
Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes.
    ACS chemical biology, 2015, Feb-20, Volume: 10, Issue:2

    Topics: Animals; Cell Line; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Molecular Structure; Phospholipase D; Pseudomonas aeruginosa; Raloxifene Hydrochloride

2015
Structure-activity relationship study of estrogen receptor down-regulators with a diphenylmethane skeleton.
    Bioorganic & medicinal chemistry, 2019, 05-15, Volume: 27, Issue:10

    Topics: Benzhydryl Compounds; Binding Sites; Cyclofenil; Down-Regulation; Estrogen Antagonists; Estrogen Receptor alpha; HEK293 Cells; Humans; Molecular Docking Simulation; Phenols; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship

2019
Design and Synthesis of Basic Selective Estrogen Receptor Degraders for Endocrine Therapy Resistant Breast Cancer.
    Journal of medicinal chemistry, 2019, 12-26, Volume: 62, Issue:24

    Topics: Animals; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Design; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Mutation; Proteolysis; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Thiophenes; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.
    Endocrinology, 1997, Volume: 138, Issue:3

    Topics: Amino Acid Sequence; Animals; Female; Humans; Isomerism; Ligands; Male; Molecular Sequence Data; Rats; Receptors, Estrogen; RNA, Messenger; Tissue Distribution

1997
Design and synthesis of novel benzothiophene analogs as selective estrogen receptor covalent antagonists against breast cancer.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Estrogen Receptor Antagonists; Female; Humans; MCF-7 Cells; Molecular Structure; Receptors, Estrogen; Structure-Activity Relationship; Thiophenes; Tumor Cells, Cultured

2021
Benzothiophene derivatives as selective estrogen receptor covalent antagonists: Design, synthesis and anti-ERα activities.
    Bioorganic & medicinal chemistry, 2021, 10-01, Volume: 47

    Topics: Dose-Response Relationship, Drug; Drug Design; Estrogen Antagonists; Estrogen Receptor alpha; Humans; Molecular Structure; Structure-Activity Relationship; Thiophenes

2021