Page last updated: 2024-09-05

r 396 and substance p

r 396 has been researched along with substance p in 3 studies

*Substance P: An eleven-amino acid neurotransmitter that appears in both the central and peripheral nervous systems. It is involved in transmission of PAIN, causes rapid contractions of the gastrointestinal smooth muscle, and modulates inflammatory and immune responses. [MeSH]

Compound Research Comparison

Studies (r 396)	Trials (r 396)	Recent Studies (post-2010) (r 396)	Studies (substance p)	Trials (substance p)	Recent Studies (post-2010) (substance p)
7	0	0	17,289	277	2,010

Protein Interaction Comparison

Protein	Taxonomy	substance p (IC50)
Substance-P receptor	Rattus norvegicus (Norway rat)	0.0005
Substance-K receptor	Rattus norvegicus (Norway rat)	0.2
Substance-K receptor	Homo sapiens (human)	0.2455
Substance-P receptor	Homo sapiens (human)	0.0011
Neuromedin-K receptor	Homo sapiens (human)	0.125
Substance-K receptor	Mesocricetus auratus (golden hamster)	0.148

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Breliere, JC; Emonds-Alt, X; Golliot, F; Le Fur, G; Pointeau, P	1
Maggi, CA; Quartara, L; Rovero, P	1
Couture, R; Culman, J; Picard, P; Prat, A; Regoli, D; Tschöpe, C; Unger, T	1

Reviews

1 review(s) available for r 396 and substance p

Article	Year
Peptide-based tachykinin NK2 receptor antagonists. Medicinal research reviews, 1995, Volume: 15, Issue:2 Topics: Animals; Dipeptides; Humans; Neurokinin A; Neurokinin B; Oligopeptides; Peptide Fragments; Peptides; Peptides, Cyclic; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P	1995

Other Studies

2 other study(ies) available for r 396 and substance p

Article	Year
Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor. Biochemical and biophysical research communications, 1993, Mar-31, Volume: 191, Issue:3 Topics: Animals; Benzamides; Binding Sites; Binding, Competitive; Cricetinae; Duodenum; Guinea Pigs; In Vitro Techniques; Kinetics; Mesocricetus; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Urinary Bladder	1993
In vivo characterization of tachykinin receptors responsible for the central cardiovascular effects of substance P and neurokinin A. Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2 Topics: Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Heart Rate; Neurokinin A; Oligopeptides; Peptide Fragments; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stereotyped Behavior; Substance P	1993

Article

Year

Characterization of the binding sites of [3H]SR 48968, a potent nonpeptide radioligand antagonist of the neurokinin-2 receptor.

Biochemical and biophysical research communications, 1993, Mar-31, Volume: 191, Issue:3

Topics: Animals; Benzamides; Binding Sites; Binding, Competitive; Cricetinae; Duodenum; Guinea Pigs; In Vitro Techniques; Kinetics; Mesocricetus; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Urinary Bladder

1993

In vivo characterization of tachykinin receptors responsible for the central cardiovascular effects of substance P and neurokinin A.

Regulatory peptides, 1993, Jul-02, Volume: 46, Issue:1-2

Topics: Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Heart Rate; Neurokinin A; Oligopeptides; Peptide Fragments; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Stereotyped Behavior; Substance P

1993